Triple #22113
high ConfidenceKnowledge triple
TP53
Tumor suppressor genes
Level 1
→
acts_as
Functional relationship
→
tumor_suppressor
Tumor suppressor function
Level 10
Original triple： p14ARF/ARF#acts as#a tumor suppressor through a p53/MDM2-dependent pathway
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Experimental + Clinical |
| Condition Dependency: | MDM2_pathway |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Cancer Prevention |
Other Info
| PMID: | 27323397 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | CDKN2A/TP53/MDM2 |
| Disease: | Cancer |