Triple #22115
high ConfidenceKnowledge triple
Nutlin-3
Small molecule drugs
Level 11
→
activates
Positive regulatory relationship
→
p53
Tumor suppressor proteins
Level 2
Original triple： Nutlin-3#impairs#erythropoiesis by activating p53
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Experimental + Clinical |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Drug targeting mechanism |
Other Info
| PMID: | 21068437 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | TP53 |
| Disease: | Erythropoiesis defect |
| Treatment: | Nutlin-3 |