Triple #22116
high ConfidenceKnowledge triple
RPS14
Ribosomal proteins
Level 2
→
inhibits
Negative regulatory relationship
→
CDK4
Kinase
Level 2
Original triple： RPS14#acts as#a CDK4/6 inhibitor linking ribosome biogenesis defects to cell cycle progression
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | experiment |
| Condition Dependency: | ribosome_biogenesis_defect |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Cell cycle regulation |
Other Info
| PMID: | 30706966 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | RPS14/CDK4/CDK6 |