Triple #22127

high Confidence

Knowledge triple

5_fluorouracil

Small molecule drugs

Level 11

activates

Positive regulatory relationship

p53

Transcription Factors

Level 2

Original triple: 5-fluorouracil#activates#p53 by inducing ribosomal stress

Evidence and Confidence

Confidence: high
Evidence Strength: experiment
Condition Dependency: Drug treatment
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Response to treatment

Other Info

PMID: 17110929
Knowledge Particle: KP4
Value Leadboard: 7
Gene Symbol: TP53
Treatment: 5-fluorouracil