Triple #6411
middle ConfidenceKnowledge triple
Cisplatin
Chemotherapy drugs
Level 11
→
induces
causation
→
relocalization_of_BER_components
DNA repair protein localization
Level 4
Original triple： Cisplatin treatment#leads to#relocalization of NPM1 and BER components from nucleoli to nucleoplasm
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Treatment response |
Other Info
| PMID: | 24648491 ↗ |
| Knowledge Particle: | KP3 |
| Value Leadboard: | 6 |
| Gene Symbol: | NPM1 |
| Treatment: | Cisplatin |
| Pathway: | BER |