Triple #6454

middle Confidence

Knowledge triple

CDH1

Adhesion proteins

Level 2

shows

Positioning relationship

aberrant_cytoplasmic_localization

Abnormal cytoplasmic localization

Level 3

Original triple: E-cadherin/ β-catenin/ and EMA#showed#aberrant cytoplasmic localization with focal aggregation in rhabdoid cells

Evidence and Confidence

Confidence: middle
Evidence Strength: experiment
Condition Dependency: rhabdoid_cells
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Loss of cell polarity

Other Info

PMID: 25031015
Knowledge Particle: KP3
Value Leadboard: 6
Gene Symbol: CDH1/ CTNNB1
Disease: Rhabdoid cells