Triple #6536

middle Confidence

Knowledge triple

BRF1

Transcription Factors

Level 2

depletion_restores

causation

TP53_pathway_activation

Signaling pathway activation

Level 5

Original triple: Derepression of small RNA transcripts and p53 pathway activation by GCN2 depletion#is restored by#BRF1 depletion

Evidence and Confidence

Confidence: middle
Evidence Strength: experiment
Condition Dependency: EIF2AK4_depletion
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: not_specified

Other Info

PMID: 28189689
Knowledge Particle: KP4
Value Leadboard: 7
Gene Symbol: eIF2AK4/BRF1