临床相关性：Diagnostic significance
A total of 3097 records found
#22234
high Confidence
Subject:
Burkitt's_lymphoma
(Tumor)
→
diagnosed_through
→
Object:
aspiration_cytology
(Diagnostic techniques)
Original: Burkitt's lymphoma#is diagnosed through#aspiration cytology
#22194
high Confidence
Subject:
NUT_locus_rearrangement
(Gene rearrangement)
→
is_associated_with
→
Object:
NUT_midline_carcinoma
(Tumor type)
Original: NUT locus rearrangements#are associated with#NUT midline carcinoma
#22191
high Confidence
Subject:
Immunohistochemistry
(Histological detection technology)
→
is_widely_used_in
→
Object:
clinical_diagnosis_of_prostatic_carcinoma
(Clinical diagnostic behavior)
Original: Immunohistochemistry#is widely used in#pathology and clinical diagnosis of prostatic carcinoma
#22190
high Confidence
Subject:
Immunohistochemistry
(Histological detection technology)
→
is_widely_used_in
→
Object:
pathology
(Pathology)
Original: Immunohistochemistry#is widely used in#pathology and clinical diagnosis of prostatic carcinoma
#22184
high Confidence
Subject:
S100_protein
(protein)
→
was_positive_in
→
Object:
all_cases
(Sample Collection)
Original: S-100 protein#was positive in#all cases
#22180
high Confidence
Subject:
Rosai-Dorfman_disease
(disease)
→
presents_as
→
Object:
painless_lymphadenopathy
(Clinical symptoms)
Original: Rosai-Dorfman disease (RDD)#presents as#painless lymphadenopathy
#22147
high Confidence
Subject:
Tumor
(Tumor tissue)
→
was_diagnosed_as
→
Object:
gangliocytoma
(Tumor type)
Original: Tumor#was diagnosed as#gangliocytoma originated from pineal body
#22146
high Confidence
Subject:
next-generation_sequencing
(Detection Technology)
→
revealed
→
Object:
EWSR1-PATZ1_fusion
(Gene fusion)
Original: Next-generation sequencing#revealed#EWSR1-PATZ1 fusion
#22141
high Confidence
Subject:
lymphocytes
(Lymphocytes)
→
negative_for
→
Object:
CD3
(Molecular markers)
Original: Lymphocytes#were positive for#CD79a and negative for CD3
#22140
high Confidence
Subject:
lymphocytes
(Lymphocytes)
→
positive_for
→
Object:
CD79a
(Molecular markers)
Original: Lymphocytes#were positive for#CD79a and negative for CD3
#22139
high Confidence
Subject:
SALL4
(Transcription Factors)
→
is
→
Object:
immunocytochemical_marker
(Molecular markers)
Original: SALL4#is#a new immunocytochemical marker
#22138
high Confidence
Subject:
Fine_needle_aspiration_cytology
(Diagnostic techniques)
→
is_used_for
→
Object:
fibrolamellar_hepatocellular_carcinoma
(Hepatocellular carcinoma subtypes)
Original: Fine needle aspiration cytology#is used for#fibrolamellar hepatocellular carcinoma
#22034
high Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic techniques)
→
distinguishes
→
Object:
follicular_variant_of_papillary_carcinoma_of_the_thyroid
(Thyroid tumor subtypes)
Original: Fine-needle aspiration cytology diagnosis#distinguishes#colloid nodule from follicular variant of papillary carcinoma of the thyroid
#22033
high Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic techniques)
→
distinguishes
→
Object:
colloid_nodule
(Thyroid nodules)
Original: Fine-needle aspiration cytology diagnosis#distinguishes#colloid nodule from follicular variant of papillary carcinoma of the thyroid
#22032
high Confidence
Subject:
AMACR
(Protein markers)
→
is_used_in
→
Object:
partial_atrophy_cases
(Pathological cases)
Original: A triple cocktail stain [p63/ HMWCK/ AMACR]#was used for#partial atrophy cases
#22031
high Confidence
Subject:
HMWCK
(Protein markers)
→
is_used_in
→
Object:
partial_atrophy_cases
(Pathological cases)
Original: A triple cocktail stain [p63/ HMWCK/ AMACR]#was used for#partial atrophy cases
#22030
high Confidence
Subject:
p63
(Protein markers)
→
is_used_in
→
Object:
partial_atrophy_cases
(Pathological cases)
Original: A triple cocktail stain [p63/ HMWCK/ AMACR]#was used for#partial atrophy cases
#22029
high Confidence
Subject:
UCHL-1
(T cell surface molecules)
→
is_expressed_on
→
Object:
T_cells
(Immune cells)
Original: Immunohistochemical stains#demonstrated#expression of the T-cell markers CD3 and UCHL-1
#22028
high Confidence
Subject:
CD3
(T cell surface molecules)
→
is_expressed_on
→
Object:
T_cells
(Immune cells)
Original: Immunohistochemical stains#demonstrated#expression of the T-cell markers CD3 and UCHL-1
#22025
high Confidence
Subject:
patient
(patient)
→
was_diagnosed_with
→
Object:
prostatic_adenocarcinoma_Gleason_3_3_6
(Tumor grade)
Original: two patients#were diagnosed with#prostatic adenocarcinoma Gleason grade 3+3=6
#22008
high Confidence
Subject:
Tumor
(Tumor)
→
was_diagnosed_as
→
Object:
myoepithelial_carcinoma
(Tumor type)
Original: Tumor#was diagnosed as#a myoepithelial carcinoma with focal rhabdoid features
#21961
high Confidence
Subject:
Immunohistochemical_stains
(Immunohistochemistry)
→
assist_in
→
Object:
tumor_diagnosis
(Tumor Diagnosis)
Original: Histochemical and immunohistochemical stains#assist in#diagnosis of this tumor
#21960
high Confidence
Subject:
Histochemical_stains
(Histological techniques)
→
assist_in
→
Object:
tumor_diagnosis
(Tumor Diagnosis)
Original: Histochemical and immunohistochemical stains#assist in#diagnosis of this tumor
#21952
high Confidence
Subject:
Urinary_cytology
(Diagnostic Methods)
→
is_useful_for
→
Object:
collecting_duct_carcinoma
(Tumor diseases)
Original: Urinary cytology#is useful for#diagnosing rare entities like collecting duct carcinoma
#21941
high Confidence
Subject:
tumor
(Tumor)
→
was_diagnosed_as
→
Object:
LELC
(disease)
Original: Tumor#was diagnosed as#LELC
#21940
high Confidence
Subject:
lymphoepithelioma
(Tumor)
→
originates_from
→
Object:
nasopharynx
(Anatomical location)
Original: Lymphoepithelioma#is#a poorly differentiated/ non-keratinizing squamous cell carcinoma of the nasopharynx
#21939
high Confidence
Subject:
lymphoepithelioma
(Tumor)
→
is
→
Object:
non-keratinizing_squamous_cell_carcinoma
(Tumor type)
Original: Lymphoepithelioma#is#a poorly differentiated/ non-keratinizing squamous cell carcinoma of the nasopharynx
#21938
high Confidence
Subject:
lymphoepithelioma
(Tumor)
→
is
→
Object:
poorly_differentiated_squamous_cell_carcinoma
(Tumor type)
Original: Lymphoepithelioma#is#a poorly differentiated/ non-keratinizing squamous cell carcinoma of the nasopharynx
#21929
high Confidence
Subject:
presence_of_two_cytologic_criteria
(Diagnostic criteria)
→
achieves
→
Object:
specificity_of_96_percent
(Diagnostic performance indicators)
Original: Presence of two cytologic criteria#achieves#a sensitivity of 85% and specificity of 96%
#21928
high Confidence
Subject:
presence_of_two_cytologic_criteria
(Diagnostic criteria)
→
achieves
→
Object:
sensitivity_of_85_percent
(Diagnostic performance indicators)
Original: Presence of two cytologic criteria#achieves#a sensitivity of 85% and specificity of 96%
#21925
high Confidence
Subject:
diagnosis_of_metastatic_clear_cell_renal_cell_carcinoma
(Diagnostic Process)
→
is_based_on
→
Object:
immunohistochemical_staining_pattern
(Immunohistochemical characteristics)
Original: Diagnosis of metastatic clear cell renal cell carcinoma#is based on#morphologic features and immunohistochemical staining pattern
#21924
high Confidence
Subject:
diagnosis_of_metastatic_clear_cell_renal_cell_carcinoma
(Diagnostic Process)
→
is_based_on
→
Object:
morphologic_features
(Morphological characteristics)
Original: Diagnosis of metastatic clear cell renal cell carcinoma#is based on#morphologic features and immunohistochemical staining pattern
#21923
high Confidence
Subject:
Ovarian_or_tubal_HGSC
(Tumor diseases)
→
can_be_detected_using
→
Object:
cervical_liquid-based_cytology
(Diagnostic techniques)
Original: Ovarian or tubal HGSC#can be detected using#cervical liquid-based cytology
#21917
high Confidence
Subject:
ETV6
(Protein coding genes)
→
translocation_confirmed_by_FISH
→
Object:
MASC
(Tumor type)
Original: Superficial parotidectomy#revealed#MASC confirmed by FISH studies for ETV6 translocation
#21912
high Confidence
Subject:
ALK-rearranged_lung_adenocarcinoma
(Molecular classification of tumors)
→
is_associated_with
→
Object:
distinctive_morphologic_patterns
(Histological phenotype)
Original: ALK-rearranged lung adenocarcinoma#is associated with#distinctive morphologic patterns
#21901
high Confidence
Subject:
IHC_slides
(Immunohistochemistry)
→
confirms
→
Object:
amelanotic_melanoma_diagnosis
(Disease diagnosis)
Original: IHC slides#confirmed#amelanotic melanoma diagnosis
#21900
high Confidence
Subject:
CD56
(Cell adhesion molecules)
→
confirms_diagnosis_of
→
Object:
large_cell_neuroendocrine_carcinoma
(disease)
Original: CD56 expression#was#a reliable marker in confirming a diagnosis of large cell neuroendocrine carcinoma
#21887
high Confidence
Subject:
Soluble_adenylyl_cyclase
(Adenylate cyclase)
→
is
→
Object:
diagnostic_marker_for_pigmented_skin_lesions
(Diagnostic markers)
Original: Soluble adenylyl cyclase (sAC)#is#a diagnostic marker for pigmented skin lesions
#21885
high Confidence
Subject:
histopathological_analysis
(Diagnostic Methods)
→
revealed
→
Object:
positive_H3_K27M_mutant_protein
(Protein modification)
Original: histopathological analysis#revealed#positive H3 K27M mutant protein and diffusely infiltrating growth
#21884
high Confidence
Subject:
Immunohistochemical analysis
(Molecular detection technology)
→
confirmed
→
Object:
diagnosis_of_intravascular_large_B-cell_lymphoma
(Disease diagnosis)
Original: immunohistochemical analysis#confirmed#diagnosis of intravascular large B-cell lymphoma
#21883
high Confidence
Subject:
renal_biopsy
(Histological examination)
→
diagnosed
→
Object:
intravascular_large_B-cell_lymphoma
(Disease diagnosis)
Original: a 41-year-old Chinese woman#was diagnosed with#intravascular large B-cell lymphoma by renal biopsy
#21882
high Confidence
Subject:
FNAB
(Imaging diagnostic technology)
→
is
→
Object:
diagnostic_technique_for_breast
(Diagnostic techniques)
Original: Fine-needle aspiration biopsy (FNAB)#is#a diagnostic technique for the breast
#21881
high Confidence
Subject:
BRG1_loss
(Loss of protein expression)
→
diagnoses
→
Object:
SMARCA4_deficient_esophageal_carcinoma
(Tumor type)
Original: SMARCA4 deficient esophageal carcinoma#was diagnosed based on#loss of BRG1 by immunostain and deep deletion confirmed by next-generation sequencing
#21870
high Confidence
Subject:
CD163
(Molecular markers)
→
is_useful_for
→
Object:
diagnosis_of_histiocytic_sarcoma
(diagnosis)
Original: CD163#is very useful for#diagnosis of histiocytic sarcoma
#21869
high Confidence
Subject:
Fine_needle_aspiration_cytology
(Diagnostic techniques)
→
provides
→
Object:
diagnostic_approach
(Diagnostic Methods)
Original: Fine needle aspiration cytology#provides#a convenient/ safe and effective diagnostic approach
#21868
high Confidence
Subject:
Eccrine_porocarcinoma
(Tumor type)
→
is_a
→
Object:
adenocarcinoma_of_eccrine_sweat_gland
(Tumor type)
Original: Eccrine porocarcinoma#is#an adenocarcinoma of the eccrine sweat gland
#21848
high Confidence
Subject:
seminoma_cells
(Tumor cells)
→
stained_positive_for
→
Object:
PLAP
(Diagnostic markers)
Original: seminoma cells#stained positive for#placental alkaline phosphatase (PLAP)
#21847
high Confidence
Subject:
MCNs
(Cystic tumors)
→
are_characterized_by
→
Object:
KRAS_mutation
(Gene mutation)
Original: IPMNs and MCNs#are characterized by#driver mutations in KRAS/GNAS (IPMNs) and KRAS (MCNs)
#21846
high Confidence
Subject:
IPMNs
(Cystic tumors)
→
are_characterized_by
→
Object:
KRAS_mutation
(Gene mutation)
Original: IPMNs and MCNs#are characterized by#driver mutations in KRAS/GNAS (IPMNs) and KRAS (MCNs)
#21841
high Confidence
Subject:
patient
(Patient characteristics)
→
diagnosed_with
→
Object:
ALCL
(Disease Type)
Original: Patient#was diagnosed with#ALCL with a rare peripheral leukemic presentation
#21840
high Confidence
Subject:
RT-PCR
(Molecular detection technology)
→
indicated
→
Object:
fusion_gene_product_of_NPM1
(Fusion gene product)
Original: RT-PCR#indicated#fusion gene product of ALK and nucleophosmin
#21839
high Confidence
Subject:
RT-PCR
(Molecular detection technology)
→
indicated
→
Object:
fusion_gene_product_of_ALK
(Fusion gene product)
Original: RT-PCR#indicated#fusion gene product of ALK and nucleophosmin
#21833
high Confidence
Subject:
Cells
(cell)
→
are_strongly_positive_for
→
Object:
CD43
(Membrane Protein)
Original: Cells#were strongly positive for#myeloperoxidase/ CD68/ lysozyme/ CD45/ CD117/ and CD43
#21832
high Confidence
Subject:
Cells
(cell)
→
are_strongly_positive_for
→
Object:
CD117
(Membrane Protein)
Original: Cells#were strongly positive for#myeloperoxidase/ CD68/ lysozyme/ CD45/ CD117/ and CD43
#21831
high Confidence
Subject:
Cells
(cell)
→
are_strongly_positive_for
→
Object:
CD45
(Membrane Protein)
Original: Cells#were strongly positive for#myeloperoxidase/ CD68/ lysozyme/ CD45/ CD117/ and CD43
#21830
high Confidence
Subject:
Cells
(cell)
→
are_strongly_positive_for
→
Object:
Lysozyme
(Enzymes)
Original: Cells#were strongly positive for#myeloperoxidase/ CD68/ lysozyme/ CD45/ CD117/ and CD43
#21829
high Confidence
Subject:
Cells
(cell)
→
are_strongly_positive_for
→
Object:
CD68
(Membrane Protein)
Original: Cells#were strongly positive for#myeloperoxidase/ CD68/ lysozyme/ CD45/ CD117/ and CD43
#21828
high Confidence
Subject:
Cells
(cell)
→
are_strongly_positive_for
→
Object:
myeloperoxidase
(Enzymes)
Original: Cells#were strongly positive for#myeloperoxidase/ CD68/ lysozyme/ CD45/ CD117/ and CD43
#21827
high Confidence
Subject:
high-molecular-weight_cytokeratin
(Cytoskeletal proteins)
→
confirms
→
Object:
presence_of_basal_cell_layer
(Organizational Structure)
Original: Immunohistochemical stains for high-molecular-weight cytokeratin#confirm#the presence of a basal cell layer
#21818
high Confidence
Subject:
Cytological_examination
(Cytology)
→
is_used_to_screen_for
→
Object:
intraepithelial_neoplasms
(Tumor)
Original: Cytological examination#is used to screen for#squamous cell carcinoma or intraepithelial neoplasms
#21817
high Confidence
Subject:
Cytological_examination
(Cytology)
→
is_used_to_screen_for
→
Object:
squamous_cell_carcinoma
(Tumor)
Original: Cytological examination#is used to screen for#squamous cell carcinoma or intraepithelial neoplasms
#21816
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_negative_for
→
Object:
CD103
(Integrin αE chain)
Original: Immunophenotyping#was negative for#CD5/ CD10/ CD11c/ CD23/ CD25/ CD38/ and CD103
#21815
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_negative_for
→
Object:
CD38
(Cell surface antigens)
Original: Immunophenotyping#was negative for#CD5/ CD10/ CD11c/ CD23/ CD25/ CD38/ and CD103
#21814
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_negative_for
→
Object:
CD25
(IL-2 receptor alpha chain)
Original: Immunophenotyping#was negative for#CD5/ CD10/ CD11c/ CD23/ CD25/ CD38/ and CD103
#21813
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_negative_for
→
Object:
CD23
(Low affinity IgE receptor)
Original: Immunophenotyping#was negative for#CD5/ CD10/ CD11c/ CD23/ CD25/ CD38/ and CD103
#21812
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_negative_for
→
Object:
CD11c
(Integrin family proteins)
Original: Immunophenotyping#was negative for#CD5/ CD10/ CD11c/ CD23/ CD25/ CD38/ and CD103
#21811
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_negative_for
→
Object:
CD10
(Cell surface antigens)
Original: Immunophenotyping#was negative for#CD5/ CD10/ CD11c/ CD23/ CD25/ CD38/ and CD103
#21810
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_negative_for
→
Object:
CD5
(T cell differentiation antigen)
Original: Immunophenotyping#was negative for#CD5/ CD10/ CD11c/ CD23/ CD25/ CD38/ and CD103
#21809
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_positive_for
→
Object:
HLA-DR
(Human Leukocyte Antigen)
Original: Immunophenotyping#was positive for#CD19/ CD20/ IgG/ kappa/ and HLA-DR
#21808
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_positive_for
→
Object:
kappa
(Immunoglobulin light chain)
Original: Immunophenotyping#was positive for#CD19/ CD20/ IgG/ kappa/ and HLA-DR
#21807
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_positive_for
→
Object:
IgG
(Immunoglobulins)
Original: Immunophenotyping#was positive for#CD19/ CD20/ IgG/ kappa/ and HLA-DR
#21806
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_positive_for
→
Object:
CD20
(B cell differentiation antigen)
Original: Immunophenotyping#was positive for#CD19/ CD20/ IgG/ kappa/ and HLA-DR
#21805
high Confidence
Subject:
Immunophenotyping
(Immunophenotyping)
→
was_positive_for
→
Object:
CD19
(B cell differentiation antigen)
Original: Immunophenotyping#was positive for#CD19/ CD20/ IgG/ kappa/ and HLA-DR
#21801
high Confidence
Subject:
Immunohistochemical_analysis
(Diagnostic Methods)
→
is_essential_for
→
Object:
definitive_diagnosis
(Diagnosis conclusion)
Original: Microscopic evaluation/ immunohistochemical analysis/ and serological tests#are essential for#reaching a definitive diagnosis
#21800
high Confidence
Subject:
Microscopic_evaluation
(Diagnostic Methods)
→
is_essential_for
→
Object:
definitive_diagnosis
(Diagnosis conclusion)
Original: Microscopic evaluation/ immunohistochemical analysis/ and serological tests#are essential for#reaching a definitive diagnosis
#21797
high Confidence
Subject:
adenocarcinoma in situ (AIS)
(Tumor type)
→
reveals
→
Object:
precursor_lesions
(Precursor lesions)
Original: AIS#reveals#a range of precursor lesions
#21791
high Confidence
Subject:
masses
(Tumor tissue)
→
identified_as
→
Object:
meningotheliomatous_meningiomas
(Tumor type)
Original: masses#identified as#meningotheliomatous meningiomas with atypical features
#21790
high Confidence
Subject:
tumor
(Tumor tissue)
→
reveals
→
Object:
SMARCA4_deep_deletion
(Gene deletion)
Original: tumor#revealed#SMARCA4 deep deletion
#21780
high Confidence
Subject:
Extraskeletal_myxoid_chondrosarcoma
(Neoplastic diseases)
→
is_characterized_by
→
Object:
recurrent_chromosomal_translocation_involving_NR4A3
(Genomic abnormalities)
Original: Extraskeletal myxoid chondrosarcoma (EMC)#is characterized by#recurrent chromosomal translocation involving NR4A3
#21765
high Confidence
Subject:
fine_needle_aspiration_cytology
(Pathological diagnosis technology)
→
was_performed_in
→
Object:
intra_abdominal_tumor
(Tumor)
Original: fine-needle aspiration cytology#was performed in#intra-abdominal tumors
#21758
high Confidence
Subject:
HMB45
(Antibody)
→
marks
→
Object:
tumor_cases
(Tumor Cases)
Original: HMB45#marked#29/31 cases
#21757
high Confidence
Subject:
S100_protein
(protein)
→
is_expressed_in
→
Object:
tumor_cases
(Tumor Cases)
Original: S100 protein#was expressed in#33/36 cases
#21756
high Confidence
Subject:
polygonal_acidophilic_cells
(Tumor cells)
→
show
→
Object:
intense_cytoplasmic_staining_for_alpha-fetoprotein
(Protein expression characteristics)
Original: hepatoid areas#are characterized by#nests and cords of polygonal acidophilic cells with prominent nucleoli and intense cytoplasmic staining for alpha-fetoprotein
#21744
high Confidence
Subject:
tumoral_cell
(Tumor cells)
→
stained_positive_with
→
Object:
CD56
(Protein markers)
Original: tumoral cells#stained strongly positive with#synaptophysin/ chromogranin/ and CD56
#21743
high Confidence
Subject:
tumoral_cell
(Tumor cells)
→
stained_positive_with
→
Object:
Chromogranin
(Protein markers)
Original: tumoral cells#stained strongly positive with#synaptophysin/ chromogranin/ and CD56
#21742
high Confidence
Subject:
tumoral_cell
(Tumor cells)
→
stained_positive_with
→
Object:
synaptophysin
(Protein markers)
Original: tumoral cells#stained strongly positive with#synaptophysin/ chromogranin/ and CD56
#21737
high Confidence
Subject:
cells
(cell)
→
are_positive_for
→
Object:
leukocyte_common_antigen
(Immune markers)
Original: Cells#were positive for#leukocyte common antigen (LCA)
#21736
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
negative_for
→
Object:
CD56
(Differentiation antigen)
Original: Lymphoma cells#were negative for#CD4/ CD19/ CD20/ CD103/ and CD56
#21735
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
negative_for
→
Object:
CD103
(Differentiation antigen)
Original: Lymphoma cells#were negative for#CD4/ CD19/ CD20/ CD103/ and CD56
#21734
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
negative_for
→
Object:
CD20
(Differentiation antigen)
Original: Lymphoma cells#were negative for#CD4/ CD19/ CD20/ CD103/ and CD56
#21733
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
negative_for
→
Object:
CD19
(Differentiation antigen)
Original: Lymphoma cells#were negative for#CD4/ CD19/ CD20/ CD103/ and CD56
#21732
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
negative_for
→
Object:
CD4
(Differentiation antigen)
Original: Lymphoma cells#were negative for#CD4/ CD19/ CD20/ CD103/ and CD56
#21731
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
positive_for
→
Object:
TCR_beta_F1
(cell receptor)
Original: Lymphoma cells#were positive for#CD2/ CD3/ CD5/ CD8/ and TCR beta F1
#21730
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
positive_for
→
Object:
CD8
(Differentiation antigen)
Original: Lymphoma cells#were positive for#CD2/ CD3/ CD5/ CD8/ and TCR beta F1
#21729
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
positive_for
→
Object:
CD5
(Differentiation antigen)
Original: Lymphoma cells#were positive for#CD2/ CD3/ CD5/ CD8/ and TCR beta F1
#21728
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
positive_for
→
Object:
CD3
(Differentiation antigen)
Original: Lymphoma cells#were positive for#CD2/ CD3/ CD5/ CD8/ and TCR beta F1
#21727
high Confidence
Subject:
lymphoma_cells
(Tumor cells)
→
positive_for
→
Object:
CD2
(Differentiation antigen)
Original: Lymphoma cells#were positive for#CD2/ CD3/ CD5/ CD8/ and TCR beta F1
#21726
high Confidence
Subject:
biopsy_specimens
(Tissue specimens)
→
revealed
→
Object:
malignant_lymphoma_of_diffuse_pleomorphic_type
(disease)
Original: Biopsy specimens#revealed#malignant lymphoma of diffuse pleomorphic type
#21723
high Confidence
Subject:
Cytological_grading_system
(Cytological grading system)
→
evaluates
→
Object:
chromatin_pattern
(Chromatin pattern)
Original: Cytological grading system#evaluates#cellular arrangement/ pleomorphism/ anisonucleosis/ myoepithelial cells/ nucleoli/ and chromatin pattern
#21722
high Confidence
Subject:
Cytological_grading_system
(Cytological grading system)
→
evaluates
→
Object:
nucleoli
(Nucleolus)
Original: Cytological grading system#evaluates#cellular arrangement/ pleomorphism/ anisonucleosis/ myoepithelial cells/ nucleoli/ and chromatin pattern
#21721
high Confidence
Subject:
Cytological_grading_system
(Cytological grading system)
→
evaluates
→
Object:
myoepithelial_cells
(Myoepithelial cells)
Original: Cytological grading system#evaluates#cellular arrangement/ pleomorphism/ anisonucleosis/ myoepithelial cells/ nucleoli/ and chromatin pattern
#21720
high Confidence
Subject:
Cytological_grading_system
(Cytological grading system)
→
evaluates
→
Object:
anisonucleosis
(Nuclear heterogeneity)
Original: Cytological grading system#evaluates#cellular arrangement/ pleomorphism/ anisonucleosis/ myoepithelial cells/ nucleoli/ and chromatin pattern
#21719
high Confidence
Subject:
Cytological_grading_system
(Cytological grading system)
→
evaluates
→
Object:
Pleomorphism
(Polymorphism)
Original: Cytological grading system#evaluates#cellular arrangement/ pleomorphism/ anisonucleosis/ myoepithelial cells/ nucleoli/ and chromatin pattern
#21718
high Confidence
Subject:
Cytological_grading_system
(Cytological grading system)
→
evaluates
→
Object:
cellular_arrangement
(Cell Arrangement)
Original: Cytological grading system#evaluates#cellular arrangement/ pleomorphism/ anisonucleosis/ myoepithelial cells/ nucleoli/ and chromatin pattern
#21716
high Confidence
Subject:
CA19-9
(Tumor markers)
→
exhibited
→
Object:
positive_expression_in_mucinous_material_in_dilated_glands
(Expression characteristics)
Original: CA19-9#exhibited#a focal/ not diffuse/ positive expression in hyperplastic epithelium and mucinous material in dilated glands
#21715
high Confidence
Subject:
CA19-9
(Tumor markers)
→
exhibited
→
Object:
focal_positive_expression_in_hyperplastic_epithelium
(Expression characteristics)
Original: CA19-9#exhibited#a focal/ not diffuse/ positive expression in hyperplastic epithelium and mucinous material in dilated glands
#21713
high Confidence
Subject:
findings
(Histological findings)
→
are_highly_suggestive_of
→
Object:
ductal_carcinoma_in_biopsy_specimens
(Tumor Diagnosis)
Original: findings#are highly suggestive of#ductal carcinoma in biopsy specimens
#21700
high Confidence
Subject:
Follicular_cells
(Tumor cells)
→
expresses
→
Object:
TTF-1
(Transcription Factors)
Original: These cells#were immunoreactive for#thyroglobulin and TTF-1
#21699
high Confidence
Subject:
Follicular_cells
(Tumor cells)
→
expresses
→
Object:
Thyroglobulin
(protein)
Original: These cells#were immunoreactive for#thyroglobulin and TTF-1
#21691
high Confidence
Subject:
fluorescence_in_situ_hybridization
(Detection Technology)
→
revealed
→
Object:
rearrangement_at_EWSR1_locus
(Gene rearrangement)
Original: Fluorescence in situ hybridization#revealed#rearrangement at EWSR1 locus
#21687
high Confidence
Subject:
CD31
(Cell surface molecules)
→
is_positive_in
→
Object:
EHE_case
(Disease Cases)
Original: CD31#is positive in#88.9% of EHE cases
#21686
high Confidence
Subject:
ERG
(Transcription Factors)
→
is_positive_in
→
Object:
EHE_case
(Disease Cases)
Original: ERG#is most frequently positive in#EHE cases
#21682
high Confidence
Subject:
intracranial_germinomas
(Tumor)
→
were_diagnosed_with
→
Object:
smear_technique
(Pathological technology)
Original: intracranial germinomas#were diagnosed with#the smear technique
#21681
high Confidence
Subject:
SMARCB1
(Protein coding genes)
→
expression_is_deficient_in
→
Object:
tumor_samples
(Tumor samples)
Original: SMARCB1 expression#was deficient in#all cases
#21680
high Confidence
Subject:
loss of immunohistochemical expression
(Loss of immunohistochemical expression)
→
diagnoses
→
Object:
FH deficiency
(Genetic metabolic defects)
Original: loss of immunohistochemical expression#diagnoses#FH deficiency
#21674
high Confidence
Subject:
Granular_cell_tumor
(Tumor type)
→
was_diagnosed_by
→
Object:
core_needle_biopsy
(Diagnostic Methods)
Original: Granular cell tumour#was diagnosed by#core needle biopsy
#21670
high Confidence
Subject:
diagnosis_of_prostate_carcinoma
(diagnosis)
→
is_based_on
→
Object:
cytoplasmic_features
(Cytoplasmic characteristics)
Original: Diagnosis of prostate carcinoma#is based on#a constellation of architectural/ nuclear/ cytoplasmic/ and ancillary features
#21669
high Confidence
Subject:
diagnosis_of_prostate_carcinoma
(diagnosis)
→
is_based_on
→
Object:
nuclear_features
(Nuclear characteristics)
Original: Diagnosis of prostate carcinoma#is based on#a constellation of architectural/ nuclear/ cytoplasmic/ and ancillary features
#21668
high Confidence
Subject:
diagnosis_of_prostate_carcinoma
(diagnosis)
→
is_based_on
→
Object:
architectural_features
(Organizational structure characteristics)
Original: Diagnosis of prostate carcinoma#is based on#a constellation of architectural/ nuclear/ cytoplasmic/ and ancillary features
#21667
high Confidence
Subject:
invasive_lung_carcinomas
(Tumor type)
→
were_classified_by
→
Object:
IASLC_system
(Classification system)
Original: Invasive lung carcinomas#were classified by#IASLC system
#21641
high Confidence
Subject:
SDHB
(Protein coding genes)
→
involved_in
→
Object:
SDH_deficient_RCC
(Disease phenotype)
Original: Gene alterations#involve#SDHB subunit in SDH-deficient RCC
#21639
high Confidence
Subject:
MKI67
(Cell proliferation marker protein)
→
is_upregulated
→
Object:
PHE_tissues
(Tissue samples)
Original: Proliferation index of Ki-67#is#10-35%
#21638
high Confidence
Subject:
FGF2
(Growth factor protein)
→
is_expressed_in
→
Object:
gliomas
(Tumor tissue)
Original: Basic FGF mRNA#is expressed in#more than 90% of human gliomas
#21603
high Confidence
Subject:
Nucleic_acid_binding_domains
(Protein domain)
→
are_targeted_by
→
Object:
autoantibodies_in_SLE
(Autoantibodies)
Original: Nucleic acid-binding domains#are targeted by#autoantibodies in SLE
#21600
high Confidence
Subject:
nucleolar_number
(Cellular substructure)
→
is_recognized_as
→
Object:
tumor_hallmark
(Disease phenotype)
Original: Larger nucleolar size and number#are recognized as#hallmark features of many tumor types
#21599
high Confidence
Subject:
nucleolar_size
(Cellular substructure)
→
is_recognized_as
→
Object:
tumor_hallmark
(Disease phenotype)
Original: Larger nucleolar size and number#are recognized as#hallmark features of many tumor types
#21559
high Confidence
Subject:
Ki-67
(Cell proliferation markers)
→
parallels
→
Object:
cell_proliferation
(Cellular Processes)
Original: Ki-67 expression#paralleled#cell proliferation in fibroblasts and lymphocytes
#21558
high Confidence
Subject:
Ki-67
(Cell proliferation markers)
→
parallels
→
Object:
cell_proliferation
(Cellular Processes)
Original: Ki-67 expression#paralleled#cell proliferation in fibroblasts and lymphocytes
#21548
high Confidence
Subject:
EMP3
(Membrane Protein)
→
expression_verified_by
→
Object:
qPCR
(Detection Technology)
Original: Western blot and qPCR#verified#expression of EMP3 in ccRCC tissues and cell lines
#21547
high Confidence
Subject:
EMP3
(Membrane Protein)
→
expression_verified_by
→
Object:
Western_blot
(Detection Technology)
Original: Western blot and qPCR#verified#expression of EMP3 in ccRCC tissues and cell lines
#21536
high Confidence
Subject:
prostate_cancers
(Tumor)
→
are_classified_by
→
Object:
Gleason's_histological_grades
(Pathological grading)
Original: Prostate cancers#are classified by#Gleason's histological grades
#21534
high Confidence
Subject:
Immunohistochemical staining
(Histological techniques)
→
labels
→
Object:
Tumor cell nucleus
(Cellular substructure)
Original: Immunohistochemical staining with Ki-67#produced#clear labeling of tumor cell nuclei
#21530
high Confidence
Subject:
FDG-PET
(Molecular imaging technology)
→
has_diagnostic_significance_in
→
Object:
oral_squamous_cell_carcinoma
(disease)
Original: FDG-PET and AgNORs#have diagnostic significance in#oral squamous cell carcinoma
#21511
high Confidence
Subject:
tumor
(Tumor tissue)
→
shows
→
Object:
papillary_RCC_type_2
(Tumor classification)
Original: The tumor#typically shows#papillary RCC/ type 2/ with eosinophilic large nucleoli and perinuclear clearing/haloes
#21495
high Confidence
Subject:
Immunostains
(Diagnostic techniques)
→
showed_reactivity_with
→
Object:
Thyroglobulin
(Thyroglobulin)
Original: immunostains#showed reactivity with#thyroglobulin
#21480
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
positive_for
→
Object:
synaptophysin
(Neuroendocrine markers)
Original: Tumor cells#were positive for#EMA/ CK AE1/AE3/ chromogranin/ synaptophysin
#21479
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
positive_for
→
Object:
Chromogranin
(Neuroendocrine markers)
Original: Tumor cells#were positive for#EMA/ CK AE1/AE3/ chromogranin/ synaptophysin
#21478
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
positive_for
→
Object:
CK_AE1/AE3
(Cytokeratin)
Original: Tumor cells#were positive for#EMA/ CK AE1/AE3/ chromogranin/ synaptophysin
#21477
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
positive_for
→
Object:
EMA
(Epithelial membrane antigen)
Original: Tumor cells#were positive for#EMA/ CK AE1/AE3/ chromogranin/ synaptophysin
#21476
high Confidence
Subject:
tissue
(organize)
→
expressed
→
Object:
CD79a
(Membrane Protein)
Original: Tissue#expressed#vimentin/ LCA/ CD10/ CD20/ CD38/ Bcl-2/ MUC-1/ CD79a
#21475
high Confidence
Subject:
tissue
(organize)
→
expressed
→
Object:
MUC-1
(Glycoprotein)
Original: Tissue#expressed#vimentin/ LCA/ CD10/ CD20/ CD38/ Bcl-2/ MUC-1/ CD79a
#21474
high Confidence
Subject:
tissue
(organize)
→
expressed
→
Object:
Bcl-2
(Anti-apoptotic proteins)
Original: Tissue#expressed#vimentin/ LCA/ CD10/ CD20/ CD38/ Bcl-2/ MUC-1/ CD79a
#21473
high Confidence
Subject:
tissue
(organize)
→
expressed
→
Object:
CD38
(Membrane Protein)
Original: Tissue#expressed#vimentin/ LCA/ CD10/ CD20/ CD38/ Bcl-2/ MUC-1/ CD79a
#21472
high Confidence
Subject:
tissue
(organize)
→
expressed
→
Object:
CD20
(Membrane Protein)
Original: Tissue#expressed#vimentin/ LCA/ CD10/ CD20/ CD38/ Bcl-2/ MUC-1/ CD79a
#21471
high Confidence
Subject:
tissue
(organize)
→
expressed
→
Object:
CD10
(Membrane Protein)
Original: Tissue#expressed#vimentin/ LCA/ CD10/ CD20/ CD38/ Bcl-2/ MUC-1/ CD79a
#21470
high Confidence
Subject:
tissue
(organize)
→
expressed
→
Object:
LCA
(common leukocyte antigen)
Original: Tissue#expressed#vimentin/ LCA/ CD10/ CD20/ CD38/ Bcl-2/ MUC-1/ CD79a
#21469
high Confidence
Subject:
tissue
(organize)
→
expressed
→
Object:
vimentin
(Intermediate filament protein)
Original: Tissue#expressed#vimentin/ LCA/ CD10/ CD20/ CD38/ Bcl-2/ MUC-1/ CD79a
#21468
high Confidence
Subject:
biopsy
(Tissue biopsy)
→
facilitates
→
Object:
definite_diagnosis
(Diagnosis conclusion)
Original: Biopsy#is recommended for#suspected cases to facilitate definite diagnosis
#21467
high Confidence
Subject:
biopsy
(Tissue biopsy)
→
is_recommended_for
→
Object:
suspected_cases
(Clinical Cases)
Original: Biopsy#is recommended for#suspected cases to facilitate definite diagnosis
#21466
high Confidence
Subject:
HMWCK
(Protein markers)
→
is_analyzed_by
→
Object:
Immunohistochemistry
(Molecular detection technology)
Original: Immunohistochemistry for high-molecular-weight cytokeratin (HMWCK)#was performed on#cases with available material
#21464
high Confidence
Subject:
TCV
(Tumor subtype)
→
can_be_diagnosed_by
→
Object:
thyroid_FNA
(Cytology)
Original: TCV#can be effectively diagnosed#on thyroid fine-needle aspiration (FNA)
#21463
high Confidence
Subject:
partial_atrophy
(Histopathological changes)
→
is_diagnosed_as
→
Object:
atypical_glands
(Pathological structure)
Original: 170 cases with partial atrophy#were diagnosed as#atypical glands by outside pathologists
#21462
high Confidence
Subject:
CD8
(T cell surface molecules)
→
is_expressed_on
→
Object:
T_cells
(Immune cells)
Original: Flow cytometry#showed#surface expression of CD2/ CD3/ CD7 (dim)/ CD8/ and CD56
#21461
high Confidence
Subject:
CD3
(T cell surface molecules)
→
is_expressed_on
→
Object:
T_cells
(Immune cells)
Original: Flow cytometry#showed#surface expression of CD2/ CD3/ CD7 (dim)/ CD8/ and CD56
#21460
high Confidence
Subject:
CD2
(T cell surface molecules)
→
is_expressed_on
→
Object:
T_cells
(Immune cells)
Original: Flow cytometry#showed#surface expression of CD2/ CD3/ CD7 (dim)/ CD8/ and CD56
#21459
high Confidence
Subject:
excisional_biopsy
(Diagnostic techniques)
→
is_recommended_to_rule_out
→
Object:
invasive_carcinoma
(Invasive carcinoma)
Original: Excisional biopsy#is recommended to rule out#ductal carcinoma in situ and/or invasive carcinoma
#21458
high Confidence
Subject:
excisional_biopsy
(Diagnostic techniques)
→
is_recommended_to_rule_out
→
Object:
ductal_carcinoma_in_situ
(Ductal carcinoma in situ)
Original: Excisional biopsy#is recommended to rule out#ductal carcinoma in situ and/or invasive carcinoma
#21457
high Confidence
Subject:
TRUS-guided_prostate_needle_core_biopsies
(Tissue biopsy sample)
→
were_diagnosed_as
→
Object:
acinar_type_adenocarcinoma
(Acinar adenocarcinoma)
Original: 251 of 863 TRUS-guided prostate needle core biopsies#were diagnosed as#acinar type adenocarcinoma
#21456
high Confidence
Subject:
Foamy_gland_carcinoma
(Tumor type)
→
is_characterized_by
→
Object:
infiltrative_pattern
(Invasive growth)
Original: Foamy gland carcinoma#is characterized by#foamy appearance/ large cytoplasm/ pyknotic nuclei/ inconspicuous nucleoli/ and infiltrative pattern
#21455
high Confidence
Subject:
Foamy_gland_carcinoma
(Tumor type)
→
is_characterized_by
→
Object:
inconspicuous_nucleoli
(Inconspicuous nucleolus)
Original: Foamy gland carcinoma#is characterized by#foamy appearance/ large cytoplasm/ pyknotic nuclei/ inconspicuous nucleoli/ and infiltrative pattern
#21454
high Confidence
Subject:
Foamy_gland_carcinoma
(Tumor type)
→
is_characterized_by
→
Object:
pyknotic_nuclei
(Pyknotic nucleus)
Original: Foamy gland carcinoma#is characterized by#foamy appearance/ large cytoplasm/ pyknotic nuclei/ inconspicuous nucleoli/ and infiltrative pattern
#21453
high Confidence
Subject:
Foamy_gland_carcinoma
(Tumor type)
→
is_characterized_by
→
Object:
large_cytoplasm
(Cytoplasmic characteristics)
Original: Foamy gland carcinoma#is characterized by#foamy appearance/ large cytoplasm/ pyknotic nuclei/ inconspicuous nucleoli/ and infiltrative pattern
#21452
high Confidence
Subject:
Foamy_gland_carcinoma
(Tumor type)
→
is_characterized_by
→
Object:
foamy_appearance
(Foamy appearance)
Original: Foamy gland carcinoma#is characterized by#foamy appearance/ large cytoplasm/ pyknotic nuclei/ inconspicuous nucleoli/ and infiltrative pattern
#21450
high Confidence
Subject:
histologic_grade
(Histological grading)
→
is_based_on
→
Object:
mitotic_frequency
(Splitting frequency)
Original: histologic grade#is based on#tubule formation/ nuclear pleomorphism/ and mitotic frequency
#21449
high Confidence
Subject:
histologic_grade
(Histological grading)
→
is_based_on
→
Object:
nuclear_pleomorphism
(Nuclear heterogeneity)
Original: histologic grade#is based on#tubule formation/ nuclear pleomorphism/ and mitotic frequency
#21448
high Confidence
Subject:
histologic_grade
(Histological grading)
→
is_based_on
→
Object:
tubule_formation
(Organizational structure characteristics)
Original: histologic grade#is based on#tubule formation/ nuclear pleomorphism/ and mitotic frequency
#21435
high Confidence
Subject:
AFP
(protein)
→
shows_strong_intracytoplasmic_positivity_in
→
Object:
tumor_cells_with_hepatic_and_bile_duct_epithelium_differentiation
(Cell differentiation characteristics)
Original: Immunohistochemistry for AFP#shows#strong intra cytoplasmic positivity in tumor cells with hepatic and bile duct epithelium differentiation
#21433
high Confidence
Subject:
Hürthle_cells
(Cell Type)
→
are_found_in
→
Object:
fine_needle_aspirates_of_thyroid_lesions
(Organizational Positioning)
Original: Hürthle cells#are found in#fine needle aspirates of thyroid lesions
#21432
high Confidence
Subject:
Adenomatoid_tumor
(Tumor type)
→
is
→
Object:
benign_neoplasm
(Benign or malignant tumor)
Original: adenomatoid tumor#is#benign neoplasm
#21423
high Confidence
Subject:
ribosomal_protein_genes_haploinsufficiency
(Gene dosage abnormalities)
→
is_implicated_in
→
Object:
5q-syndrome
(Genetic disorders)
Original: Haploinsufficiency of ribosomal protein genes#is implicated in#Diamond-Blackfan anemia and 5q-syndrome
#21422
high Confidence
Subject:
ribosomal_protein_genes_haploinsufficiency
(Gene dosage abnormalities)
→
is_implicated_in
→
Object:
Diamond-Blackfan_anemia
(Genetic disorders)
Original: Haploinsufficiency of ribosomal protein genes#is implicated in#Diamond-Blackfan anemia and 5q-syndrome
#21419
high Confidence
Subject:
Peptide_RS
(Peptides)
→
enables
→
Object:
delineation_from_noncancerous_tissues
(Tissue typing)
Original: Peptide RS#enables#improved HCC micrometastasis discrimination and delineation from noncancerous tissues
#21418
high Confidence
Subject:
Peptide_RS
(Peptides)
→
enables
→
Object:
HCC_micrometastasis_discrimination
(Disease phenotype)
Original: Peptide RS#enables#improved HCC micrometastasis discrimination and delineation from noncancerous tissues
#21390
high Confidence
Subject:
carcinoma_AgNOR_area
(Cell morphology index)
→
is_larger_than
→
Object:
adenoma_AgNOR_area
(Cell morphology index)
Original: Cross-sectional area of carcinoma AgNORs#was significantly larger than#that of adenoma
#21385
high Confidence
Subject:
argyrophilic_nucleolar_organizer_region_staining
(Silver staining of nucleolar organizer region)
→
correlates_with
→
Object:
brain_tumor_grading
(Brain tumor grading)
Original: argyrophilic nucleolar organizer region staining#correlates with#brain tumor classification and grading
#21384
high Confidence
Subject:
argyrophilic_nucleolar_organizer_region_staining
(Silver staining of nucleolar organizer region)
→
correlates_with
→
Object:
brain_tumor_classification
(Brain tumor classification)
Original: argyrophilic nucleolar organizer region staining#correlates with#brain tumor classification and grading
#21376
high Confidence
Subject:
AgNOR_count
(Molecular markers)
→
is_used_as
→
Object:
index_of_malignancy_grade
(Tumor grade)
Original: AgNOR count#was used as#an index of malignancy grade
#21370
high Confidence
Subject:
Intratubular_embryonal_carcinoma
(Histopathological entities)
→
is_variety_of
→
Object:
germ_cell_tumor
(Histopathological entities)
Original: Intratubular embryonal carcinoma#is referred to as#a variety of germ cell tumors
#21352
high Confidence
Subject:
Pemphigus_vulgaris
(disease)
→
diagnosed_by
→
Object:
immunofluorescence
(Diagnostic Methods)
Original: Pemphigus vulgaris#was diagnosed by#histological examination and immunofluorescence
#21351
high Confidence
Subject:
Pemphigus_vulgaris
(disease)
→
diagnosed_by
→
Object:
histological_examination
(Diagnostic Methods)
Original: Pemphigus vulgaris#was diagnosed by#histological examination and immunofluorescence
#21350
high Confidence
Subject:
Scrape_cytology
(Cytology)
→
suggests
→
Object:
Paget disease of the nipple
(disease)
Original: Scrape cytology#suggested#Paget's disease of the nipple
#21349
high Confidence
Subject:
Pemphigus_vulgaris
(disease)
→
confirmed_by
→
Object:
immunocytochemical_examination
(Diagnostic Methods)
Original: Pemphigus vulgaris#was confirmed by#histological and immunocytochemical examination
#21348
high Confidence
Subject:
Pemphigus_vulgaris
(disease)
→
confirmed_by
→
Object:
histological_examination
(Diagnostic Methods)
Original: Pemphigus vulgaris#was confirmed by#histological and immunocytochemical examination
#21341
high Confidence
Subject:
Transbronchial_lung_biopsy
(Diagnostic techniques)
→
is_effective_method_for
→
Object:
diagnosis_of_Pulmonary_intravascular_large_B_cell_lymphoma
(Disease diagnosis)
Original: Transbronchial lung biopsy#is#an effective method to confirm the diagnosis
#21338
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
express
→
Object:
CD79A
(Surface antigen)
Original: Tumor cells#expressed#mature B cell-associated antigens CD20 and CD79a
#21337
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
express
→
Object:
CD20
(Surface antigen)
Original: Tumor cells#expressed#mature B cell-associated antigens CD20 and CD79a
#21329
high Confidence
Subject:
Mucoepidermoid_carcinoma_of_submandibular_gland
(Tumor type)
→
is_observed_in
→
Object:
pleural_fluid
(Body fluid specimens)
Original: Mucoepidermoid carcinoma of submandibular gland origin#is observed in#pleural fluid
#21327
high Confidence
Subject:
correct_diagnosis
(Diagnosis conclusion)
→
was_made_by
→
Object:
open_biopsy_revealing_necrosis_due_to_infarction_of_intraductal_papilloma
(Histological evidence)
Original: Correct diagnosis#was made by#open biopsy revealing necrosis due to infarction of intraductal papilloma
#21326
high Confidence
Subject:
cellular_features
(Cell characteristics)
→
are_considered_as
→
Object:
evidence_of_ductal_carcinoma_of_the_breast
(Breast ductal carcinoma evidence)
Original: Cellular features#were considered as#evidence of ductal carcinoma of the breast
#21318
high Confidence
Subject:
FUS::TFCP2_fusion_transcript
(Fusion gene)
→
confirms
→
Object:
RMS_diagnosis
(Diagnosis conclusion)
Original: Molecular studies#revealed#a FUS::TFCP2 fusion transcript confirming RMS diagnosis
#21311
high Confidence
Subject:
polypoid_tumor_of_cervical_trachea
(Tumor)
→
was_recognized_by
→
Object:
fiberoptic_bronchoscopy
(Endoscopic techniques)
Original: Polypoid tumor of the cervical trachea#was recognized by#neck X-ray/ CT scan/ and fiberoptic bronchoscopy
#21310
high Confidence
Subject:
polypoid_tumor_of_cervical_trachea
(Tumor)
→
was_recognized_by
→
Object:
CT_scan
(Imaging Technology)
Original: Polypoid tumor of the cervical trachea#was recognized by#neck X-ray/ CT scan/ and fiberoptic bronchoscopy
#21309
high Confidence
Subject:
polypoid_tumor_of_cervical_trachea
(Tumor)
→
was_recognized_by
→
Object:
neck_X-ray
(Imaging Technology)
Original: Polypoid tumor of the cervical trachea#was recognized by#neck X-ray/ CT scan/ and fiberoptic bronchoscopy
#21308
high Confidence
Subject:
LELCs
(Tumor)
→
are_designated_as
→
Object:
tumors_arising_outside_nasopharynx
(Tumor type)
Original: Lymphoepithelioma-like carcinomas (LELCs)#are designated as#tumors arising outside the nasopharynx
#21307
high Confidence
Subject:
FNAC
(Detection Technology)
→
allows
→
Object:
diagnosis_of_specific_renal_tumors_in_infancy
(Disease diagnosis)
Original: FNAC#allows#diagnosis of specific renal tumors in infancy
#21306
high Confidence
Subject:
parachordoma
(Tumor)
→
is
→
Object:
benign_tumor
(Tumor nature)
Original: parachordoma#is#a benign tumor with cytological features of malignancy
#21305
high Confidence
Subject:
extrarenal_malignant_rhabdoid_tumors
(Tumor type)
→
were_confirmed_by
→
Object:
electron_microscopic_examination
(Ultrastructural examination)
Original: extrarenal malignant rhabdoid tumors#were confirmed by#histologic and electron microscopic examination
#21304
high Confidence
Subject:
extrarenal_malignant_rhabdoid_tumors
(Tumor type)
→
were_confirmed_by
→
Object:
histologic_examination
(Pathology testing)
Original: extrarenal malignant rhabdoid tumors#were confirmed by#histologic and electron microscopic examination
#21272
high Confidence
Subject:
well-demarcated_tumor
(Tumor tissue)
→
diagnostic_of
→
Object:
seminoma
(Tumor type)
Original: left testis#has#a well-demarcated tumor diagnostic of seminoma
#21267
high Confidence
Subject:
bladder_cytology
(Cytology)
→
is_used_to_monitor
→
Object:
early_stage_bladder_cancer
(Disease phenotype)
Original: Bladder cytology#is used to#detect and monitor early stage bladder cancer
#21266
high Confidence
Subject:
bladder_cytology
(Cytology)
→
is_used_to_detect
→
Object:
early_stage_bladder_cancer
(Disease phenotype)
Original: Bladder cytology#is used to#detect and monitor early stage bladder cancer
#21255
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_immunoreactive_with
→
Object:
CD10
(Protein molecules)
Original: Neoplastic cells#are immunoreactive with#CD10
#21252
high Confidence
Subject:
High-grade_serous_carcinoma
(Tumor diseases)
→
is
→
Object:
most_common_epithelial_carcinoma_of_tubo-ovarian_region
(Disease Definition)
Original: High-grade serous carcinoma (HGSC)#is#the most common epithelial carcinoma of the tubo-ovarian region
#21239
high Confidence
Subject:
adenosquamous_carcinoma
(Tumor type)
→
classified_as
→
Object:
adenosquamous_carcinoma
(Tumor type)
Original: 143 cases#included#endocervical adenocarcinoma/ combined adenocarcinoma-squamous carcinoma/ and adenosquamous carcinoma
#21238
high Confidence
Subject:
combined_adenocarcinoma-squamous_carcinoma
(Tumor type)
→
classified_as
→
Object:
adenosquamous_carcinoma
(Tumor type)
Original: 143 cases#included#endocervical adenocarcinoma/ combined adenocarcinoma-squamous carcinoma/ and adenosquamous carcinoma
#21237
high Confidence
Subject:
endocervical_adenocarcinoma
(Tumor type)
→
classified_as
→
Object:
adenocarcinoma
(Tumor type)
Original: 143 cases#included#endocervical adenocarcinoma/ combined adenocarcinoma-squamous carcinoma/ and adenosquamous carcinoma
#21236
high Confidence
Subject:
squash_cytologic_preparation
(Slice Cytology Preparation)
→
diagnoses
→
Object:
metastatic_HCC_of_brain
(Disease diagnosis)
Original: A case of metastatic HCC of brain#was diagnosed by#squash cytologic preparation
#21235
high Confidence
Subject:
FNA
(Fine needle aspiration)
→
diagnoses
→
Object:
low-grade_lymphoma_of_MALT
(Disease diagnosis)
Original: Low-grade lymphoma of MALT#was diagnosed by#FNA
#21234
high Confidence
Subject:
histology
(Histological examination)
→
confirms
→
Object:
cytologic_diagnosis
(Cytological diagnosis)
Original: Histology and gene rearrangement studies#confirmed#cytologic diagnosis
#21233
high Confidence
Subject:
immunophenotyping_study
(Immunophenotyping)
→
suggests
→
Object:
diagnosis_of_low-grade_B-cell_lymphoma_of_MALT
(Disease diagnosis)
Original: Cytomorphology coupled with immunophenotyping study#suggested#diagnosis of low-grade B-cell lymphoma of MALT
#21218
high Confidence
Subject:
Fine-needle_aspiration
(Diagnostic techniques)
→
is_routinely_performed_in
→
Object:
osseous_lesions
(Bone lesions)
Original: Fine-needle aspiration (FNA)#is routinely performed in#osseous lesions
#21208
high Confidence
Subject:
histology
(Histological detection technology)
→
Reports
→
Object:
amelanotic_malignant_melanoma
(disease)
Original: histology#reported#amelanotic malignant melanoma
#21207
high Confidence
Subject:
fine-needle_aspiration_cytology
(Cytological detection technology)
→
diagnoses
→
Object:
amelanotic_melanoma_recurrence
(Disease recurrence)
Original: amelanotic melanoma recurrence#was diagnosed by#fine-needle aspiration cytology
#21182
high Confidence
Subject:
Anaplastic_carcinoma_of_the_thyroid
(Tumor type)
→
is_diagnosed_in
→
Object:
thyroid_aspirates
(Clinical samples)
Original: Anaplastic carcinoma of the thyroid#is diagnosed in#1/519 thyroid aspirates
#21169
high Confidence
Subject:
EWSR1
(Protein coding genes)
→
undergoes
→
Object:
gene_rearrangement
(Genetic variation)
Original: EWSR1 gene#undergoes#a rearrangement
#21164
high Confidence
Subject:
Calculation
(Pathological characteristics)
→
supports
→
Object:
diagnosis_of_pilomatrixoma
(Disease diagnosis)
Original: presence of foreign body-type giant cells/ nucleated squamous cells/ and calcification#supported#a diagnosis of pilomatrixoma
#21163
high Confidence
Subject:
nucleated_squamous_cells
(Epithelial cells)
→
supports
→
Object:
diagnosis_of_pilomatrixoma
(Disease diagnosis)
Original: presence of foreign body-type giant cells/ nucleated squamous cells/ and calcification#supported#a diagnosis of pilomatrixoma
#21162
high Confidence
Subject:
foreign_body-type_giant_cells
(Histiocytes)
→
supports
→
Object:
diagnosis_of_pilomatrixoma
(Disease diagnosis)
Original: presence of foreign body-type giant cells/ nucleated squamous cells/ and calcification#supported#a diagnosis of pilomatrixoma
#21158
high Confidence
Subject:
CD17
(Cell surface molecules)
→
exhibits
→
Object:
negative_immunohistochemical_finding
(Immunohistochemical characteristics)
Original: CD 17#exhibits#negative immunohistochemical findings
#21157
high Confidence
Subject:
AE1/AE3
(Cytokeratin complex)
→
exhibits
→
Object:
negative_immunohistochemical_finding
(Immunohistochemical characteristics)
Original: AE1/AE3#exhibits#negative immunohistochemical findings
#21156
high Confidence
Subject:
HMB-45
(protein)
→
exhibits
→
Object:
positive_immunohistochemical_finding
(Immunohistochemical characteristics)
Original: HMB-45#exhibits#positive immunohistochemical findings
#21155
high Confidence
Subject:
Melan_A
(protein)
→
exhibits
→
Object:
positive_immunohistochemical_finding
(Immunohistochemical characteristics)
Original: Melan A#exhibits#positive immunohistochemical findings
#21154
high Confidence
Subject:
protein_S-100
(protein)
→
exhibits
→
Object:
positive_immunohistochemical_finding
(Immunohistochemical characteristics)
Original: protein S-100#exhibits#positive immunohistochemical findings
#21153
high Confidence
Subject:
vimentin
(Intermediate filament protein)
→
exhibits
→
Object:
positive_immunohistochemical_finding
(Immunohistochemical characteristics)
Original: vimentin#exhibits#positive immunohistochemical findings
#21152
high Confidence
Subject:
Burkitt's_lymphoma
(Malignant tumors)
→
is_characterized_as
→
Object:
highly_aggressive_mature_B-cell_neoplasm
(Tumor phenotype)
Original: Burkitt's lymphoma#is characterized as#a highly aggressive mature B-cell neoplasm
#21139
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD138
(Membrane protein markers)
Original: Tumor cells#were positive for#CD79a and CD138
#21138
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD79A
(Membrane protein markers)
Original: Tumor cells#were positive for#CD79a and CD138
#21132
high Confidence
Subject:
intranuclear_inclusions
(Nuclear inclusions)
→
is_associated_with
→
Object:
papillary_carcinoma
(Tumor type)
Original: Intranuclear inclusions/ papillary and/or sheet arrangements/ nuclear grooves/ powdery chromatin/ nuclear molding/ high cellularity/ and small nucleoli#were significantly associated with#papillary carcinoma
#21104
high Confidence
Subject:
fine-needle_aspiration_biopsy
(Diagnostic Tools)
→
is_used_for
→
Object:
diagnosis_of_high-grade_pulmonary_neuroendocrine_carcinoma
(Disease diagnosis)
Original: fine-needle aspiration biopsy#is used for#diagnosis of high-grade pulmonary neuroendocrine carcinoma
#21075
high Confidence
Subject:
seminoma_cells
(Tumor cells)
→
stained_negative_for
→
Object:
cytokeratin
(Diagnostic markers)
Original: seminoma cells#stained negative for#low molecular and broad-spectrum cytokeratin
#21074
high Confidence
Subject:
IPMNs
(Cystic tumors)
→
are_characterized_by
→
Object:
GNAS_mutation
(Gene mutation)
Original: IPMNs and MCNs#are characterized by#driver mutations in KRAS/GNAS (IPMNs) and KRAS (MCNs)
#21071
high Confidence
Subject:
criteria
(Diagnostic criteria)
→
permit
→
Object:
distinction_between_repair_atypia_and_carcinoma
(Diagnostic differentiation)
Original: Criteria#permit#distinction between repair atypia and carcinoma
#21069
high Confidence
Subject:
abnormal_cells
(Tumor cell type)
→
strongly_positive_for
→
Object:
CD30
(Membrane receptor protein)
Original: Abnormal cells#were strongly positive for#CD30
#21068
high Confidence
Subject:
Polycythemia_Vera
(disease)
→
can_be_diagnosed_by
→
Object:
Cytology
(Cytology)
Original: PV#can be diagnosed by#cytology
#21067
high Confidence
Subject:
Blasts
(Hematopoietic cells)
→
express
→
Object:
CD34
(Cell surface markers)
Original: Blasts#express#CD45 and CD34
#21066
high Confidence
Subject:
Blasts
(Hematopoietic cells)
→
express
→
Object:
CD45
(Cell surface markers)
Original: Blasts#express#CD45 and CD34
#21060
high Confidence
Subject:
neuroectodermal_cells
(Neuroectodermal cells)
→
diagnosed_as
→
Object:
Ewing's_sarcoma
(Tumor type)
Original: It#was diagnosed as#Ewing's sarcoma
#21055
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_immunoreactive_to
→
Object:
ERG
(Transcription Factors)
Original: The tumor cells#are immunoreactive to#CD99 and ERG
#21054
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_immunoreactive_to
→
Object:
CD99
(Cell surface proteins)
Original: The tumor cells#are immunoreactive to#CD99 and ERG
#21039
high Confidence
Subject:
atypical_glandular_cell_lesions
(Cytopathological abnormalities)
→
are_diagnosed_by
→
Object:
cervical_cytological_examination
(Cytology)
Original: atypical glandular cell lesions#are diagnosed by#cervical cytological examination
#21030
high Confidence
Subject:
cytological_features
(Cytological characteristics)
→
are_confirmed_by
→
Object:
Immunohistochemistry
(Immunohistochemistry)
Original: cytological features#are confirmed by#histopathology and immunohistochemistry
#21029
high Confidence
Subject:
cytological_features
(Cytological characteristics)
→
are_confirmed_by
→
Object:
histopathology
(Histopathology)
Original: cytological features#are confirmed by#histopathology and immunohistochemistry
#21028
high Confidence
Subject:
Serological_tests
(Diagnostic Methods)
→
is_essential_for
→
Object:
definitive_diagnosis
(Diagnosis conclusion)
Original: Microscopic evaluation/ immunohistochemical analysis/ and serological tests#are essential for#reaching a definitive diagnosis
#21015
high Confidence
Subject:
Cells
(cell)
→
are_strongly_positive_for
→
Object:
leukocyte_common_antigen
(Diagnostic molecular markers)
Original: Cells#were strongly positive for#leukocyte common antigen
#21000
high Confidence
Subject:
adenocarcinoma in situ (AIS)
(Tumor type)
→
shows
→
Object:
moderate_to_coarse_granularity
(Cell morphology)
Original: adenocarcinoma in situ (AIS)#shows#nuclear enlargement/ oval nuclear shape/ hyperchromasia/ and moderate-to-coarse granularity
#20999
high Confidence
Subject:
adenocarcinoma in situ (AIS)
(Tumor type)
→
shows
→
Object:
hyperchromasia
(Cell morphology)
Original: adenocarcinoma in situ (AIS)#shows#nuclear enlargement/ oval nuclear shape/ hyperchromasia/ and moderate-to-coarse granularity
#20998
high Confidence
Subject:
adenocarcinoma in situ (AIS)
(Tumor type)
→
shows
→
Object:
oval_nuclear_shape
(Cell morphology)
Original: adenocarcinoma in situ (AIS)#shows#nuclear enlargement/ oval nuclear shape/ hyperchromasia/ and moderate-to-coarse granularity
#20997
high Confidence
Subject:
adenocarcinoma in situ (AIS)
(Tumor type)
→
shows
→
Object:
nuclear_enlargement
(Cell morphology)
Original: adenocarcinoma in situ (AIS)#shows#nuclear enlargement/ oval nuclear shape/ hyperchromasia/ and moderate-to-coarse granularity
#20995
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD79A
(B cell markers)
Original: tumor cells#are#positive for CD20 and CD79a
#20994
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD20
(B cell markers)
Original: tumor cells#are#positive for CD20 and CD79a
#20989
high Confidence
Subject:
orbital_meningiomas
(Tumor type)
→
are_diagnosed_by
→
Object:
fine-needle_aspiration_cytology
(Diagnostic techniques)
Original: orbital meningiomas#are diagnosed by#fine-needle aspiration cytology (FNAC)
#20987
high Confidence
Subject:
absence_of_basal_cells
(Histological characteristics)
→
confirms
→
Object:
diagnosis_of_cancer
(Disease diagnosis)
Original: absence of basal cells#confirms#the diagnosis of cancer
#20986
high Confidence
Subject:
background_intestinal_metaplasia
(Changes in tissue morphology)
→
is_present_in
→
Object:
Barrett_esophagus
(disease)
Original: Background intestinal metaplasia#was present in#Barrett esophagus
#20985
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
express
→
Object:
CD123
(Protein markers)
Original: Malignant cells#express#bright CD45/ HLA-DR/ and CD33/ dim CD4/ heterogeneous CD56/ and partial CD123
#20984
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
express
→
Object:
CD56
(Protein markers)
Original: Malignant cells#express#bright CD45/ HLA-DR/ and CD33/ dim CD4/ heterogeneous CD56/ and partial CD123
#20983
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
express
→
Object:
CD4
(Protein markers)
Original: Malignant cells#express#bright CD45/ HLA-DR/ and CD33/ dim CD4/ heterogeneous CD56/ and partial CD123
#20982
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
express
→
Object:
CD33
(Protein markers)
Original: Malignant cells#express#bright CD45/ HLA-DR/ and CD33/ dim CD4/ heterogeneous CD56/ and partial CD123
#20981
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
express
→
Object:
HLA-DR
(Protein markers)
Original: Malignant cells#express#bright CD45/ HLA-DR/ and CD33/ dim CD4/ heterogeneous CD56/ and partial CD123
#20980
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
express
→
Object:
CD45
(Protein markers)
Original: Malignant cells#express#bright CD45/ HLA-DR/ and CD33/ dim CD4/ heterogeneous CD56/ and partial CD123
#20979
high Confidence
Subject:
tumor
(Tumor tissue)
→
are_positive_for
→
Object:
FOSB
(Transcription Factors)
Original: Tumors#are positive for#nuclear and cytoplasmic FOSB
#20963
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
NSE
(Protein markers)
Original: Tumor cells#are positive for#synaptophysin/ GFAP/ CD117/ S100/ Cam5.2/ and NSE
#20962
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
Cam5.2
(Protein markers)
Original: Tumor cells#are positive for#synaptophysin/ GFAP/ CD117/ S100/ Cam5.2/ and NSE
#20961
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
S100
(Protein markers)
Original: Tumor cells#are positive for#synaptophysin/ GFAP/ CD117/ S100/ Cam5.2/ and NSE
#20960
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD117
(Protein markers)
Original: Tumor cells#are positive for#synaptophysin/ GFAP/ CD117/ S100/ Cam5.2/ and NSE
#20959
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
GFAP
(Protein markers)
Original: Tumor cells#are positive for#synaptophysin/ GFAP/ CD117/ S100/ Cam5.2/ and NSE
#20958
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
synaptophysin
(Protein markers)
Original: Tumor cells#are positive for#synaptophysin/ GFAP/ CD117/ S100/ Cam5.2/ and NSE
#20928
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD34
(Diagnostic markers)
Original: tumor cells#are positive for#CD34
#20927
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD31
(Diagnostic markers)
Original: tumor cells#are positive for#CD31
#20920
high Confidence
Subject:
pleomorphic_cells
(Tumor cells)
→
showed
→
Object:
black_pigments
(Cell morphology)
Original: infilating nests of pleomorphic cells#showed#prominent nucleoli and black pigments
#20919
high Confidence
Subject:
pleomorphic_cells
(Tumor cells)
→
showed
→
Object:
prominent_nucleoli
(Cell morphology)
Original: infilating nests of pleomorphic cells#showed#prominent nucleoli and black pigments
#20918
high Confidence
Subject:
rhabdoid_component
(Organizational structure)
→
shows
→
Object:
prominent_nucleoli
(Cell morphology)
Original: rhabdoid component#shows#abundant eosinophilic cytoplasm/ eccentric nuclei/ and prominent nucleoli
#20917
high Confidence
Subject:
rhabdoid_component
(Organizational structure)
→
shows
→
Object:
eccentric_nuclei
(Cell morphology)
Original: rhabdoid component#shows#abundant eosinophilic cytoplasm/ eccentric nuclei/ and prominent nucleoli
#20916
high Confidence
Subject:
rhabdoid_component
(Organizational structure)
→
shows
→
Object:
abundant_eosinophilic_cytoplasm
(Cell morphology)
Original: rhabdoid component#shows#abundant eosinophilic cytoplasm/ eccentric nuclei/ and prominent nucleoli
#20911
high Confidence
Subject:
anaplastic_lymphoma_kinase
(Protein kinase)
→
overexpression_helps_distinguish
→
Object:
IMT
(Tumor)
Original: overexpression of anaplastic lymphoma kinase#helps distinguish#IMT from malignant mimics
#20896
high Confidence
Subject:
initial_pathological_diagnosis
(Diagnosis conclusion)
→
was
→
Object:
benign_pleomorphic_adenoma
(Benign tumors)
Original: Initial pathological diagnosis#was#benign pleomorphic adenoma
#20895
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
Melan-A
(Protein markers)
Original: Tumor cells#stain positive for#Mic-2 (CD-99 antigen)/ vimentin/ synaptophysin/ and Melan-A
#20894
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
synaptophysin
(Protein markers)
Original: Tumor cells#stain positive for#Mic-2 (CD-99 antigen)/ vimentin/ synaptophysin/ and Melan-A
#20893
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
vimentin
(Protein markers)
Original: Tumor cells#stain positive for#Mic-2 (CD-99 antigen)/ vimentin/ synaptophysin/ and Melan-A
#20892
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
Mic-2_(CD-99_antigen)
(Protein markers)
Original: Tumor cells#stain positive for#Mic-2 (CD-99 antigen)/ vimentin/ synaptophysin/ and Melan-A
#20842
high Confidence
Subject:
tumor
(Tumor)
→
was_positive_for
→
Object:
vimentin
(Protein markers)
Original: tumor#was positive for#neuroendocrine markers and vimentin
#20841
high Confidence
Subject:
tumor
(Tumor)
→
was_positive_for
→
Object:
neuroendocrine_markers
(Protein markers)
Original: tumor#was positive for#neuroendocrine markers and vimentin
#20838
high Confidence
Subject:
NUT_protein_expression
(Protein expression)
→
is_detected_by
→
Object:
immunohistochemistry_with_C52B1
(Detection Technology)
Original: NUT protein expression#is detected by#immunohistochemistry using rabbit monoclonal antibody C52B1
#20837
high Confidence
Subject:
calretinin
(Calcium Binding Protein)
→
shows_expression_in
→
Object:
granular_cell_tumor
(Tumor type)
Original: Granular cell tumor#shows expression of#CD56/ CD68/ S-100 protein/ inhibin/ and calretinin
#20836
high Confidence
Subject:
inhibin
(Glycoprotein hormones)
→
shows_expression_in
→
Object:
granular_cell_tumor
(Tumor type)
Original: Granular cell tumor#shows expression of#CD56/ CD68/ S-100 protein/ inhibin/ and calretinin
#20835
high Confidence
Subject:
S-100_protein
(Calcium Binding Protein)
→
shows_expression_in
→
Object:
granular_cell_tumor
(Tumor type)
Original: Granular cell tumor#shows expression of#CD56/ CD68/ S-100 protein/ inhibin/ and calretinin
#20834
high Confidence
Subject:
CD68
(Lysosome-associated proteins)
→
shows_expression_in
→
Object:
granular_cell_tumor
(Tumor type)
Original: Granular cell tumor#shows expression of#CD56/ CD68/ S-100 protein/ inhibin/ and calretinin
#20833
high Confidence
Subject:
CD56
(Cell membrane glycoprotein)
→
shows_expression_in
→
Object:
granular_cell_tumor
(Tumor type)
Original: Granular cell tumor#shows expression of#CD56/ CD68/ S-100 protein/ inhibin/ and calretinin
#20829
high Confidence
Subject:
adipophilin
(Protein markers)
→
detected_in
→
Object:
cases
(Case)
Original: Expression of epithelial membrane antigen/ perilipin and adipophilin#were detected#in all cases
#20828
high Confidence
Subject:
perilipin
(Protein markers)
→
detected_in
→
Object:
cases
(Case)
Original: Expression of epithelial membrane antigen/ perilipin and adipophilin#were detected#in all cases
#20827
high Confidence
Subject:
epithelial_membrane_antigen
(Protein markers)
→
detected_in
→
Object:
cases
(Case)
Original: Expression of epithelial membrane antigen/ perilipin and adipophilin#were detected#in all cases
#20826
high Confidence
Subject:
Cytodiagnostic_criteria
(Diagnostic criteria)
→
distinguish
→
Object:
thyroid_neoplasms
(disease)
Original: Cytodiagnostic criteria#distinguish#Hashimoto's thyroiditis from thyroid neoplasms
#20825
high Confidence
Subject:
Cytodiagnostic_criteria
(Diagnostic criteria)
→
distinguish
→
Object:
Hashimoto's_thyroiditis
(disease)
Original: Cytodiagnostic criteria#distinguish#Hashimoto's thyroiditis from thyroid neoplasms
#20824
high Confidence
Subject:
histopathologic_diagnoses
(Pathological diagnosis)
→
are_grouped_as
→
Object:
malignant
(Malignant)
Original: Histopathologic diagnoses#are grouped as#benign/ follicular neoplasm/ and malignant
#20823
high Confidence
Subject:
histopathologic_diagnoses
(Pathological diagnosis)
→
are_grouped_as
→
Object:
follicular_neoplasm
(Follicular tumor)
Original: Histopathologic diagnoses#are grouped as#benign/ follicular neoplasm/ and malignant
#20822
high Confidence
Subject:
histopathologic_diagnoses
(Pathological diagnosis)
→
are_grouped_as
→
Object:
benign
(benign)
Original: Histopathologic diagnoses#are grouped as#benign/ follicular neoplasm/ and malignant
#20821
high Confidence
Subject:
thyroid_FNA_cytology_samples
(Fine needle aspiration cytology specimen)
→
are_examined_for
→
Object:
preoperative_evaluation_of_thyroid_nodules
(Preoperative evaluation)
Original: thyroid FNA cytology samples#are examined for#preoperative evaluation of thyroid nodules
#20820
high Confidence
Subject:
HER2+_neoplasms
(Tumor subtype)
→
demonstrate
→
Object:
centered_macronucleoli
(Cell morphology)
Original: HER2+ neoplasms#demonstrate#centered macronucleoli
#20819
high Confidence
Subject:
cytology_smears
(Cytology samples)
→
are_scored_for
→
Object:
morphological_features
(Cell morphology)
Original: cytology smears#are scored for#morphological features
#20810
high Confidence
Subject:
PRNRP
(Tumor subtype)
→
is_a_subtype_of
→
Object:
papillary_renal_cell_carcinoma
(Tumor type)
Original: PRNRP#is a subtype of#papillary renal cell carcinoma with characteristic morphological/ immunophenotypic/ and molecular features
#20804
high Confidence
Subject:
malignant cells
(Tumor cells)
→
are_positive_for
→
Object:
prostatic-specific antigen
(Tumor markers)
Original: malignant cells#were positive for#prostatic-specific antigen
#20803
high Confidence
Subject:
malignant cells
(Tumor cells)
→
are_consistent_with
→
Object:
prostatic adenocarcinoma
(Malignant tumors)
Original: cytologic preparations#revealed#cells consistent with prostatic adenocarcinoma
#20802
high Confidence
Subject:
Prominent_nucleoli
(Nucleolar characteristics)
→
had
→
Object:
practical_significance_in_pathologic_diagnosis
(Significance of pathological diagnosis)
Original: Prominent nucleoli#had#practical significance in pathologic diagnosis
#20801
high Confidence
Subject:
Prostatic_needle_biopsy
(Histological samples)
→
included
→
Object:
adenocarcinoma_case
(Adenocarcinoma Cases)
Original: 250 cases of prostatic needle biopsy#included#100 cases of adenocarcinoma
#20799
high Confidence
Subject:
atypical_lymphoid_cells
(Abnormal lymphocytes)
→
are_identified_as
→
Object:
T-cell_nature
(Cell type characteristics)
Original: atypical lymphoid cells#are identified as#t-cell nature
#20796
high Confidence
Subject:
FNA_smear
(Cytology)
→
combined_with
→
Object:
HMCK_immunohistochemistry
(Immunohistochemistry)
Original: FNA smears#together with#HMCK immunohistochemistry can be useful for the cytologic differential diagnosis of renal tumors
#20793
high Confidence
Subject:
Meningiomas
(Meningioma)
→
are_classified_as
→
Object:
malignant_meningioma
(Malignant meningioma)
Original: 120 meningiomas#are classified as#101 benign/ 15 atypical/ and 4 malignant meningiomas
#20792
high Confidence
Subject:
Meningiomas
(Meningioma)
→
are_classified_as
→
Object:
atypical_meningioma
(Atypical meningioma)
Original: 120 meningiomas#are classified as#101 benign/ 15 atypical/ and 4 malignant meningiomas
#20791
high Confidence
Subject:
Meningiomas
(Meningioma)
→
are_classified_as
→
Object:
benign_meningioma
(Benign meningioma)
Original: 120 meningiomas#are classified as#101 benign/ 15 atypical/ and 4 malignant meningiomas
#20790
high Confidence
Subject:
Primary_lesion_of_bulbar_conjunctiva
(Lesions)
→
is_classified_as
→
Object:
Stage_IB_acquired_melanosis
(Stage IB Acquired Melanosis)
Original: Primary lesion of bulbar conjunctiva#is classified as#Stage IB acquired melanosis
#20789
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
show_positive_expression_for
→
Object:
CK8/18
(Cell markers)
Original: tumor cells#showed positive expression for#CK7/ CD117/ EMA/ vimentin/ and CK8/18
#20788
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
show_positive_expression_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: tumor cells#showed positive expression for#CK7/ CD117/ EMA/ vimentin/ and CK8/18
#20787
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
show_positive_expression_for
→
Object:
EMA
(Cell markers)
Original: tumor cells#showed positive expression for#CK7/ CD117/ EMA/ vimentin/ and CK8/18
#20786
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
show_positive_expression_for
→
Object:
CD117
(Cell markers)
Original: tumor cells#showed positive expression for#CK7/ CD117/ EMA/ vimentin/ and CK8/18
#20785
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
show_positive_expression_for
→
Object:
CK7
(Cell markers)
Original: tumor cells#showed positive expression for#CK7/ CD117/ EMA/ vimentin/ and CK8/18
#20782
high Confidence
Subject:
KRAS_mutation
(Gene mutation)
→
is_identified_in
→
Object:
lymph_node_fine-needle_aspiration_specimen
(Clinical sample type)
Original: Advanced pulmonary adenocarcinoma harboring KRAS mutation#is identified in#lymph node fine-needle aspiration specimens
#20781
high Confidence
Subject:
clear_cell_papillary_renal_cell_carcinoma
(Tumor type)
→
shows
→
Object:
calcium_oxalate_crystal_deposition
(Tissue composition characteristics)
Original: Histology of clear cell papillary renal cell carcinoma#is distinctive for#sieve-like architecture/ eosinophilic cytoplasm/ large nuclei with prominent nucleoli/ and calcium oxalate crystal deposition
#20780
high Confidence
Subject:
clear_cell_papillary_renal_cell_carcinoma
(Tumor type)
→
shows
→
Object:
prominent_nucleolus
(Cell morphology)
Original: Histology of clear cell papillary renal cell carcinoma#is distinctive for#sieve-like architecture/ eosinophilic cytoplasm/ large nuclei with prominent nucleoli/ and calcium oxalate crystal deposition
#20779
high Confidence
Subject:
clear_cell_papillary_renal_cell_carcinoma
(Tumor type)
→
shows
→
Object:
large_nucleus
(Cell morphology)
Original: Histology of clear cell papillary renal cell carcinoma#is distinctive for#sieve-like architecture/ eosinophilic cytoplasm/ large nuclei with prominent nucleoli/ and calcium oxalate crystal deposition
#20778
high Confidence
Subject:
clear_cell_papillary_renal_cell_carcinoma
(Tumor type)
→
shows
→
Object:
eosinophilic_cytoplasm
(Cell morphology)
Original: Histology of clear cell papillary renal cell carcinoma#is distinctive for#sieve-like architecture/ eosinophilic cytoplasm/ large nuclei with prominent nucleoli/ and calcium oxalate crystal deposition
#20777
high Confidence
Subject:
clear_cell_papillary_renal_cell_carcinoma
(Tumor type)
→
shows
→
Object:
sieve-like_architecture
(Tissue morphology)
Original: Histology of clear cell papillary renal cell carcinoma#is distinctive for#sieve-like architecture/ eosinophilic cytoplasm/ large nuclei with prominent nucleoli/ and calcium oxalate crystal deposition
#20776
high Confidence
Subject:
melanoma
(Malignant tumors)
→
shows
→
Object:
dermal_naevocytic_differentiation
(Cell differentiation characteristics)
Original: Histopathological criteria to distinguish naevi from melanoma#include#lack of pagetoid lateral spread/ absence of mitotic activity in deep dermal component/ and dermal naevocytic differentiation
#20775
high Confidence
Subject:
melanoma
(Malignant tumors)
→
shows
→
Object:
absence_of_mitotic_activity_in_deep_dermal_component
(Tissue morphology)
Original: Histopathological criteria to distinguish naevi from melanoma#include#lack of pagetoid lateral spread/ absence of mitotic activity in deep dermal component/ and dermal naevocytic differentiation
#20774
high Confidence
Subject:
melanoma
(Malignant tumors)
→
shows
→
Object:
lack_of_pagetoid_lateral_spread
(Tissue morphology)
Original: Histopathological criteria to distinguish naevi from melanoma#include#lack of pagetoid lateral spread/ absence of mitotic activity in deep dermal component/ and dermal naevocytic differentiation
#20773
high Confidence
Subject:
acral-lentiginous_naevus
(Benign pigmented nevus)
→
shows
→
Object:
prominent_nucleolus
(Cell morphology)
Original: Acral-lentiginous naevi#are distinguished by#elongation of rete ridges/ melanocyte proliferation/ and hyperchromatic nuclei with prominent nucleoli
#20772
high Confidence
Subject:
acral-lentiginous_naevus
(Benign pigmented nevus)
→
shows
→
Object:
hyperchromatic_nucleus
(Cell morphology)
Original: Acral-lentiginous naevi#are distinguished by#elongation of rete ridges/ melanocyte proliferation/ and hyperchromatic nuclei with prominent nucleoli
#20771
high Confidence
Subject:
acral-lentiginous_naevus
(Benign pigmented nevus)
→
shows
→
Object:
melanocyte_proliferation
(Cell proliferation characteristics)
Original: Acral-lentiginous naevi#are distinguished by#elongation of rete ridges/ melanocyte proliferation/ and hyperchromatic nuclei with prominent nucleoli
#20770
high Confidence
Subject:
acral-lentiginous_naevus
(Benign pigmented nevus)
→
shows
→
Object:
elongation_of_rete_ridges
(Tissue morphology)
Original: Acral-lentiginous naevi#are distinguished by#elongation of rete ridges/ melanocyte proliferation/ and hyperchromatic nuclei with prominent nucleoli
#20769
high Confidence
Subject:
acral-lentiginous_naevus
(Benign pigmented nevus)
→
is_classified_as
→
Object:
special_entity
(Histological entity)
Original: Acral-lentiginous naevus#is classified as#a special entity distinct from other acral naevi
#20768
high Confidence
Subject:
classic_medulloblastoma
(Tumor type)
→
shows
→
Object:
fine_chromatin
(Cell morphology)
Original: Cytologic features of classic medulloblastoma#include#small cells with rounded/ uniform nuclei with fine chromatin
#20767
high Confidence
Subject:
classic_medulloblastoma
(Tumor type)
→
shows
→
Object:
uniform_nucleus
(Cell morphology)
Original: Cytologic features of classic medulloblastoma#include#small cells with rounded/ uniform nuclei with fine chromatin
#20766
high Confidence
Subject:
classic_medulloblastoma
(Tumor type)
→
shows
→
Object:
rounded_nucleus
(Cell morphology)
Original: Cytologic features of classic medulloblastoma#include#small cells with rounded/ uniform nuclei with fine chromatin
#20765
high Confidence
Subject:
classic_medulloblastoma
(Tumor type)
→
shows
→
Object:
small_cell
(Cell morphology)
Original: Cytologic features of classic medulloblastoma#include#small cells with rounded/ uniform nuclei with fine chromatin
#20764
high Confidence
Subject:
malignant_cell
(Tumor cells)
→
shows
→
Object:
visible_nucleolus
(Cell morphology)
Original: Malignant cells#had#high nucleocytoplasmic ratios/ highly pleomorphic and frequently polylobated nuclei with coarse chromatin and 1-3 visible nucleoli
#20763
high Confidence
Subject:
malignant_cell
(Tumor cells)
→
shows
→
Object:
coarse_chromatin
(Cell morphology)
Original: Malignant cells#had#high nucleocytoplasmic ratios/ highly pleomorphic and frequently polylobated nuclei with coarse chromatin and 1-3 visible nucleoli
#20762
high Confidence
Subject:
malignant_cell
(Tumor cells)
→
shows
→
Object:
polylobated_nucleus
(Cell morphology)
Original: Malignant cells#had#high nucleocytoplasmic ratios/ highly pleomorphic and frequently polylobated nuclei with coarse chromatin and 1-3 visible nucleoli
#20761
high Confidence
Subject:
malignant_cell
(Tumor cells)
→
shows
→
Object:
pleomorphic_nucleus
(Cell morphology)
Original: Malignant cells#had#high nucleocytoplasmic ratios/ highly pleomorphic and frequently polylobated nuclei with coarse chromatin and 1-3 visible nucleoli
#20760
high Confidence
Subject:
malignant_cell
(Tumor cells)
→
shows
→
Object:
high_nucleocytoplasmic_ratio
(Cell morphology)
Original: Malignant cells#had#high nucleocytoplasmic ratios/ highly pleomorphic and frequently polylobated nuclei with coarse chromatin and 1-3 visible nucleoli
#20741
high Confidence
Subject:
ultrastructural_examination
(Diagnostic techniques)
→
provides
→
Object:
diagnosis_of_myofibrosarcoma
(Diagnosis conclusion)
Original: Ultrastructural examination#provides#the most confident diagnosis of myofibrosarcoma
#20729
high Confidence
Subject:
trypsin
(Enzymes)
→
stains_positive_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#stain positive for#BCL10 and trypsin
#20728
high Confidence
Subject:
BCL10
(protein)
→
stains_positive_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#stain positive for#BCL10 and trypsin
#20727
high Confidence
Subject:
BCL10
(protein)
→
is_biomarker_for
→
Object:
pancreatic_acinar_cell_carcinoma
(Neoplastic diseases)
Original: BCL10#is#biomarker for pancreatic acinar cell carcinoma
#20709
high Confidence
Subject:
MIB1
(Cell proliferation markers)
→
helps_to_differentiate_from
→
Object:
high-grade_primary_squamous_cell_carcinoma_of_thyroid
(Tumor type)
Original: Intermediate proliferation index (MIB-1 labeling index is usually less than 20%)#helps to differentiate it from#high-grade primary squamous cell carcinoma of the thyroid
#20708
high Confidence
Subject:
CD5
(Cell surface antigens)
→
is_key_feature_to_differentiate_from
→
Object:
high-grade_squamous_cell_carcinoma
(Tumor type)
Original: Positive immunoreactivity for CD5#is a key feature to differentiate it from#undifferentiated carcinoma/ poorly differentiated carcinoma/ medullary carcinoma/ and high-grade squamous cell carcinoma
#20707
high Confidence
Subject:
CD5
(Cell surface antigens)
→
is_key_feature_to_differentiate_from
→
Object:
medullary_carcinoma
(Tumor type)
Original: Positive immunoreactivity for CD5#is a key feature to differentiate it from#undifferentiated carcinoma/ poorly differentiated carcinoma/ medullary carcinoma/ and high-grade squamous cell carcinoma
#20706
high Confidence
Subject:
CD5
(Cell surface antigens)
→
is_key_feature_to_differentiate_from
→
Object:
poorly_differentiated_carcinoma
(Tumor type)
Original: Positive immunoreactivity for CD5#is a key feature to differentiate it from#undifferentiated carcinoma/ poorly differentiated carcinoma/ medullary carcinoma/ and high-grade squamous cell carcinoma
#20705
high Confidence
Subject:
CD5
(Cell surface antigens)
→
is_key_feature_to_differentiate_from
→
Object:
undifferentiated_carcinoma
(Tumor type)
Original: Positive immunoreactivity for CD5#is a key feature to differentiate it from#undifferentiated carcinoma/ poorly differentiated carcinoma/ medullary carcinoma/ and high-grade squamous cell carcinoma
#20704
high Confidence
Subject:
cell_of_origin
(Cell Type)
→
enables
→
Object:
accurate_classification_of_thyroid_lesions
(Diagnostic Process)
Original: Cell of origin#enables#accurate classification of thyroid lesions
#20703
high Confidence
Subject:
neoplastic_nuclei
(Nucleus)
→
reacted_with
→
Object:
FLI1
(Transcription Factors)
Original: Neoplastic nuclei#reacted with#Fli-1
#20702
high Confidence
Subject:
neoplastic_cell_membranes
(Cell membrane)
→
reacted_with
→
Object:
CD99
(Cell surface proteins)
Original: Neoplastic cell membranes#reacted with#CD99 (MIC2)
#20701
high Confidence
Subject:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
→
is_valuable_for
→
Object:
preoperative_diagnosis_of_benign_tumor
(Diagnosis conclusion)
Original: Fine-needle aspiration biopsy#is valuable for#establishing the preoperative diagnosis of benign tumor
#20693
high Confidence
Subject:
Patients
(patient)
→
underwent
→
Object:
axillary_sentinel_node_biopsy
(Tissue biopsy)
Original: Patients#underwent#breast conserving surgery and axillary sentinel node biopsy
#20686
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_negative_for
→
Object:
keratin
(Cytoskeletal proteins)
Original: Tumors#were negative for#keratin
#20685
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_positive_for
→
Object:
GFAP
(glial fibrillary acid protein)
Original: Tumors#were positive for#CD99/ desmin/ myogenin/ MyoD1/ S100/ Sox10/ CD34/ GFAP
#20684
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_positive_for
→
Object:
CD34
(Cell surface proteins)
Original: Tumors#were positive for#CD99/ desmin/ myogenin/ MyoD1/ S100/ Sox10/ CD34/ GFAP
#20683
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_positive_for
→
Object:
Sox10
(Transcription Factors)
Original: Tumors#were positive for#CD99/ desmin/ myogenin/ MyoD1/ S100/ Sox10/ CD34/ GFAP
#20682
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_positive_for
→
Object:
S100
(Calcium Binding Protein)
Original: Tumors#were positive for#CD99/ desmin/ myogenin/ MyoD1/ S100/ Sox10/ CD34/ GFAP
#20681
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_positive_for
→
Object:
MyoD1
(Transcription Factors)
Original: Tumors#were positive for#CD99/ desmin/ myogenin/ MyoD1/ S100/ Sox10/ CD34/ GFAP
#20680
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_positive_for
→
Object:
myogenin
(Transcription Factors)
Original: Tumors#were positive for#CD99/ desmin/ myogenin/ MyoD1/ S100/ Sox10/ CD34/ GFAP
#20679
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_positive_for
→
Object:
desmin
(Cytoskeletal proteins)
Original: Tumors#were positive for#CD99/ desmin/ myogenin/ MyoD1/ S100/ Sox10/ CD34/ GFAP
#20678
high Confidence
Subject:
tumors
(Tumor diseases)
→
were_positive_for
→
Object:
CD99
(Cell surface proteins)
Original: Tumors#were positive for#CD99/ desmin/ myogenin/ MyoD1/ S100/ Sox10/ CD34/ GFAP
#20666
high Confidence
Subject:
CD34
(Cell surface molecules)
→
is_positive_in
→
Object:
EHE_case
(Disease Cases)
Original: CD34#is positive in#77.8% of EHE cases
#20665
high Confidence
Subject:
cancer_associated_fibroblasts
(Fibroblasts)
→
are
→
Object:
useful_cytological_finding_for_diagnosing_pancreatic_ductal_adenocarcinoma
(Diagnostic markers)
Original: cancer-associated fibroblasts#are#a useful cytological finding for diagnosing pancreatic ductal adenocarcinoma
#20644
high Confidence
Subject:
diagnosis
(Diagnostic Process)
→
is
→
Object:
primary_gastric_Hodgkin_lymphoma
(disease)
Original: diagnosis#is#primary gastric Hodgkin lymphoma
#20643
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
show_nuclear_positivity_for
→
Object:
SALL4
(Transcription Factors)
Original: Tumor cells#show nuclear positivity for#SALL4
#20642
high Confidence
Subject:
EUS-FNA
(Diagnostic techniques)
→
is
→
Object:
useful_method_for_evaluation_of_gastrointestinal_lesions
(Diagnostic Methods)
Original: EUS-FNA#is#a useful method for evaluation of gastrointestinal lesions
#20641
high Confidence
Subject:
cytogenetic_studies
(Genetic analysis)
→
were_consistent_with
→
Object:
t(15;19)(q13;p13.1)
(Chromosomal translocation)
Original: cytogenetic studies#were consistent with#t(15;19)(q13;p13.1) in both cases
#20640
high Confidence
Subject:
cytologic_smear_preparations
(Pathological technology)
→
have_been_used_in
→
Object:
intraoperative_diagnosis_of_CNS_tumors
(Diagnostic techniques)
Original: Cytologic smear preparations#have been used in#the intraoperative diagnosis of central nervous system tumors
#20633
high Confidence
Subject:
Fine_needle_aspiration_cytology
(Diagnostic techniques)
→
is_diagnostic_for
→
Object:
cutaneous_cystic_lesions
(Cystic skin lesions)
Original: Fine needle aspiration cytology#is diagnostic for#cutaneous cystic lesions
#20632
high Confidence
Subject:
Fine_needle_aspiration_cytology
(Diagnostic techniques)
→
is_used_for
→
Object:
cutaneous_lesions
(Skin lesions)
Original: Fine needle aspiration cytology#is used for#cutaneous lesions
#20625
high Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
synaptophysin
(Synaptophysin)
Original: Neoplastic cells#are positive for#CD99 and synaptophysin
#20624
high Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD99
(Cell surface proteins)
Original: Neoplastic cells#are positive for#CD99 and synaptophysin
#20612
high Confidence
Subject:
BCOR-CCNB3-positive_sarcomas
(Tumor diseases)
→
show
→
Object:
CCNB3_immunostaining
(Molecular markers)
Original: BCOR-CCNB3-positive sarcomas#show#CCNB3 immunostaining
#20611
high Confidence
Subject:
tumor
(Tumor tissue)
→
was_labeled_as
→
Object:
malignant_epithelioid_hemangioendothelioma
(Disease phenotype)
Original: tumor#was labeled as#malignant EHE due to spindle cell morphology/ marked cellularity/ and necrosis
#20608
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD68
(Surface markers)
Original: Tumor cells#are positive for#myeloperoxidase and CD68
#20607
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
myeloperoxidase
(Enzymes)
Original: Tumor cells#are positive for#myeloperoxidase and CD68
#20606
high Confidence
Subject:
correct_diagnosis
(Diagnosis conclusion)
→
applies_to
→
Object:
fibrolamellar_hepatocellular_carcinoma
(Tumor diseases)
Original: Cytologic findings of FL-HCC#permit#a correct diagnosis of this liver malignancy
#20605
high Confidence
Subject:
cytologic_findings
(Cytological characteristics)
→
permit
→
Object:
correct_diagnosis
(Diagnosis conclusion)
Original: Cytologic findings of FL-HCC#permit#a correct diagnosis of this liver malignancy
#20604
high Confidence
Subject:
Fine needle aspiration
(Fine needle aspiration)
→
reveals
→
Object:
epithelial cells with high nuclear/cytoplasmic ratio
(Cell morphology)
Original: Fine needle aspiration#reveals#epithelial cells with high nuclear/cytoplasmic ratio
#20603
high Confidence
Subject:
Ultrastructural examination
(Cell ultrastructure detection)
→
distinguishes
→
Object:
Hairy cell leukemia
(disease)
Original: Ultrastructural examination#distinguishes#splenic lymphoma with circulating lymphocytes from hairy cell leukemia
#20602
high Confidence
Subject:
Ultrastructural examination
(Cell ultrastructure detection)
→
distinguishes
→
Object:
splenic lymphoma with circulating lymphocytes
(disease)
Original: Ultrastructural examination#distinguishes#splenic lymphoma with circulating lymphocytes from hairy cell leukemia
#20600
high Confidence
Subject:
CA19-9
(Carbohydrate antigen)
→
shows
→
Object:
diffuse_membranous_staining
(Protein expression characteristics)
Original: tumor cells#show#diffuse and strong membranous staining for CK(AE1/AE3)/ CK7/ and CA19-9
#20599
high Confidence
Subject:
CK7
(Cytokeratin)
→
shows
→
Object:
diffuse_membranous_staining
(Protein expression characteristics)
Original: tumor cells#show#diffuse and strong membranous staining for CK(AE1/AE3)/ CK7/ and CA19-9
#20598
high Confidence
Subject:
CK_AE1/AE3
(Cytokeratin)
→
shows
→
Object:
diffuse_membranous_staining
(Protein expression characteristics)
Original: tumor cells#show#diffuse and strong membranous staining for CK(AE1/AE3)/ CK7/ and CA19-9
#20596
high Confidence
Subject:
diagnosis_of_prostate_carcinoma
(diagnosis)
→
is_based_on
→
Object:
ancillary_features
(Auxiliary Features)
Original: Diagnosis of prostate carcinoma#is based on#a constellation of architectural/ nuclear/ cytoplasmic/ and ancillary features
#20595
high Confidence
Subject:
apoptotic_bodies
(apoptotic body)
→
should_be_added_to
→
Object:
diagnostic_features_for_prostate_cancer
(Diagnostic features)
Original: Presence of apoptotic bodies#should be added to#diagnostic features for prostate cancer on needle biopsy
#20573
high Confidence
Subject:
PTEN
(Protein coding genes)
→
mutation_results_in
→
Object:
benign_hamartomas
(Benign hamartoma)
Original: Germline PTEN mutations#result in#cancer predisposition/ macrocephaly/ and benign hamartomas
#20572
high Confidence
Subject:
PTEN
(Protein coding genes)
→
mutation_results_in
→
Object:
macrocephaly
(Clinical phenotype - macrocephaly)
Original: Germline PTEN mutations#result in#cancer predisposition/ macrocephaly/ and benign hamartomas
#20535
high Confidence
Subject:
CST1
(Caspase inhibitors)
→
is_significantly_elevated_in
→
Object:
serum
(serum)
Original: CST1 expression#was significantly elevated in#ESCC tissues and serum
#20534
high Confidence
Subject:
CST1
(Caspase inhibitors)
→
is_significantly_elevated_in
→
Object:
ESCC_tissues
(Tumor tissue)
Original: CST1 expression#was significantly elevated in#ESCC tissues and serum
#20516
high Confidence
Subject:
PHE_tissues
(Tissue samples)
→
expresses
→
Object:
ERG
(Transcription Factors)
Original: PHE tissues#expressed#CD31 and ERG
#20515
high Confidence
Subject:
PHE_tissues
(Tissue samples)
→
expresses
→
Object:
CD31
(Endothelial marker protein)
Original: PHE tissues#expressed#CD31 and ERG
#20353
high Confidence
Subject:
fibrillarin
(Ribosome-associated proteins)
→
is_overexpressed_in
→
Object:
prostate_adenocarcinomas
(Tumor tissue)
Original: fibrillarin#is overexpressed in#PIN lesions and prostate adenocarcinomas
#20352
high Confidence
Subject:
fibrillarin
(Ribosome-associated proteins)
→
is_overexpressed_in
→
Object:
PIN_lesions
(Preneoplastic lesions)
Original: fibrillarin#is overexpressed in#PIN lesions and prostate adenocarcinomas
#20351
high Confidence
Subject:
adenocarcinoma_in_situ_area
(Tumor tissue)
→
shows
→
Object:
AgNOR_staining_dots
(Histological markers)
Original: Areas of adenocarcinoma in situ#show#significantly more AgNOR staining dots than normal areas
#20347
high Confidence
Subject:
Ki-67-positive_nuclei
(Nuclear markers)
→
supports
→
Object:
diagnosis_of_parathyroid_carcinoma
(Disease phenotype)
Original: Ki-67-positive nuclei#support#diagnosis of parathyroid carcinoma
#20346
high Confidence
Subject:
Ki-67
(Protein markers)
→
is_a_marker_of
→
Object:
malignancy_in_parathyroid_tumors
(Disease phenotype)
Original: Ki-67#is#a valuable marker of malignancy in parathyroid tumors
#20345
high Confidence
Subject:
Ki-67
(Cell proliferation markers)
→
is_useful_for
→
Object:
diagnostic_malignant_parathyroid_tumors
(Diagnosis of malignant parathyroid tumors)
Original: Ki-67 immunostaining#is useful for#diagnosing malignant parathyroid tumors
#20330
high Confidence
Subject:
MKI67
(Cell proliferation-related proteins)
→
is_expressed_in
→
Object:
advanced_gastric_cancer_patients
(patient)
Original: Ki-67 antigen expression#was studied in#advanced gastric cancer patients
#20323
high Confidence
Subject:
invasive_adenocarcinoma
(Adenocarcinoma)
→
shows
→
Object:
increased_signal
(molecular signaling)
Original: Precursor lesion (high-grade PIN) and invasive adenocarcinoma lesions#showed#marked increase in signal compared to non-neoplastic luminal epithelium
#20322
high Confidence
Subject:
high-grade_PIN
(Precursor lesions)
→
shows
→
Object:
increased_signal
(molecular signaling)
Original: Precursor lesion (high-grade PIN) and invasive adenocarcinoma lesions#showed#marked increase in signal compared to non-neoplastic luminal epithelium
#20319
high Confidence
Subject:
cytological_examination
(Cytology)
→
helps_in
→
Object:
early_detection_of_malignant_oral_lesions
(Early detection of oral malignant lesions)
Original: Cytological examination#helps in#early detection of malignant oral lesions
#20299
high Confidence
Subject:
T-cell_receptor_gamma_gene
(TCR Gene)
→
shows
→
Object:
monoclonal_rearrangement
(Gene rearrangement)
Original: Molecular evaluation#demonstrated#monoclonal rearrangement of the T-cell receptor gamma gene
#20298
high Confidence
Subject:
Molecular_detection
(Diagnostic Tests)
→
is_used_in
→
Object:
diagnosis_of_fumarate_hydratase-deficient_uterine_leiomyomas
(Disease diagnosis)
Original: Clinicopathological/ immunohistochemistry/ and molecular detection#are used in#diagnosis of fumarate hydratase-deficient uterine leiomyomas
#20297
high Confidence
Subject:
Immunohistochemistry_detection
(Diagnostic Tests)
→
is_used_in
→
Object:
diagnosis_of_fumarate_hydratase-deficient_uterine_leiomyomas
(Disease diagnosis)
Original: Clinicopathological/ immunohistochemistry/ and molecular detection#are used in#diagnosis of fumarate hydratase-deficient uterine leiomyomas
#20296
high Confidence
Subject:
Clinicopathological_detection
(Diagnostic Tests)
→
is_used_in
→
Object:
diagnosis_of_fumarate_hydratase-deficient_uterine_leiomyomas
(Disease diagnosis)
Original: Clinicopathological/ immunohistochemistry/ and molecular detection#are used in#diagnosis of fumarate hydratase-deficient uterine leiomyomas
#20283
high Confidence
Subject:
IGCN
(Histopathological entities)
→
is_recognized_with
→
Object:
abundant_cytoplasm
(Cell morphology)
Original: IGCN#is recognized with#large cells/ hyperchromatic nuclei/ nucleoli/ and abundant cytoplasm
#20282
high Confidence
Subject:
IGCN
(Histopathological entities)
→
is_recognized_with
→
Object:
nucleoli
(Cell morphology)
Original: IGCN#is recognized with#large cells/ hyperchromatic nuclei/ nucleoli/ and abundant cytoplasm
#20281
high Confidence
Subject:
IGCN
(Histopathological entities)
→
is_recognized_with
→
Object:
hyperchromatic_nuclei
(Cell morphology)
Original: IGCN#is recognized with#large cells/ hyperchromatic nuclei/ nucleoli/ and abundant cytoplasm
#20280
high Confidence
Subject:
IGCN
(Histopathological entities)
→
is_recognized_with
→
Object:
large_cells
(Cell morphology)
Original: IGCN#is recognized with#large cells/ hyperchromatic nuclei/ nucleoli/ and abundant cytoplasm
#20273
high Confidence
Subject:
NUT
(Protein coding genes)
→
shows
→
Object:
strong_positivity_in_IHC
(Immunohistochemical expression)
Original: Immunohistochemical staining#demonstrated#strong positivity for vimentin and NUT
#20262
high Confidence
Subject:
computed_tomography_scan
(Imaging tests)
→
confirms
→
Object:
3-cm_nodule_in_right_parietal_lobe_of_brain
(Image Discovery)
Original: Computed tomography scan#confirmed#a 3-cm nodule in the right parietal lobe of the brain
#20261
high Confidence
Subject:
gene_rearrangement_study
(Gene rearrangement analysis)
→
confirms
→
Object:
cytologic_diagnosis
(Cytological diagnosis)
Original: Histology and gene rearrangement studies#confirmed#cytologic diagnosis
#20251
high Confidence
Subject:
immunohistochemical_staining
(Detection Technology)
→
revealed
→
Object:
no_reactivity_for_TTF-1
(Protein expression)
Original: immunohistochemical staining#revealed#strong expression of GATA3 and mammaglobin with no reactivity for thyroglobulin or TTF-1
#20250
high Confidence
Subject:
immunohistochemical_staining
(Detection Technology)
→
revealed
→
Object:
no_reactivity_for_thyroglobulin
(Protein expression)
Original: immunohistochemical staining#revealed#strong expression of GATA3 and mammaglobin with no reactivity for thyroglobulin or TTF-1
#20249
high Confidence
Subject:
immunohistochemical_staining
(Detection Technology)
→
revealed
→
Object:
strong_expression_of_mammaglobin
(Protein expression)
Original: immunohistochemical staining#revealed#strong expression of GATA3 and mammaglobin with no reactivity for thyroglobulin or TTF-1
#20248
high Confidence
Subject:
immunohistochemical_staining
(Detection Technology)
→
revealed
→
Object:
strong_expression_of_GATA3
(Protein expression)
Original: immunohistochemical staining#revealed#strong expression of GATA3 and mammaglobin with no reactivity for thyroglobulin or TTF-1
#20247
high Confidence
Subject:
Cytologic_diagnosis
(Diagnosis conclusion)
→
was
→
Object:
LCNEC
(Neoplastic diseases)
Original: Original cytologic diagnosis#was#LCNEC in nine cases
#20244
high Confidence
Subject:
malignant_rhabdoid_tumors_of_the_spine
(Tumor)
→
are_classified_as
→
Object:
rare_pediatric_neoplasms
(disease)
Original: Malignant rhabdoid tumors of the spine#are classified as#rare pediatric neoplasms
#20243
high Confidence
Subject:
this_tumour
(Tumor)
→
is_classified_as
→
Object:
undifferentiated_malignant_lymphoma
(disease)
Original: This tumour#is classified as#an undifferentiated malignant lymphoma
#20242
high Confidence
Subject:
alkaline_phosphatase_activity
(Enzyme activity)
→
distinguishes
→
Object:
Telangiectatic_osteosarcoma
(Tumor diseases)
Original: alkaline phosphatase activity#distinguishes#TOS from other osteolytic bone tumors
#20241
high Confidence
Subject:
FNA_biopsy
(Cytological detection technology)
→
demonstrates_value_in
→
Object:
osteosarcoma_diagnosis_in_adrenal_gland
(Diagnosis conclusion)
Original: FNA biopsy combined with immunocytochemistry#demonstrated value in#diagnosing osteosarcoma from an unusual location such as the adrenal gland
#20234
high Confidence
Subject:
VIN_3
(Disease classification)
→
is_defined_by
→
Object:
abnormal_mitotic_figures_throughout_epithelium
(Abnormal cell division phase)
Original: VIN 3#is defined by#nuclear abnormalities and abnormal mitotic figures throughout most or all of the epithelium
#20233
high Confidence
Subject:
VIN_3
(Disease classification)
→
is_defined_by
→
Object:
nuclear_abnormalities
(Nuclear abnormalities)
Original: VIN 3#is defined by#nuclear abnormalities and abnormal mitotic figures throughout most or all of the epithelium
#20232
high Confidence
Subject:
VIN_2
(Disease classification)
→
is_defined_by
→
Object:
mitotic_figures_confined_to_basal_half_of_epithelium
(Cell division phase positioning)
Original: VIN 2#is defined by#nuclear atypia and mitotic figures confined to the basal half of the epithelium
#20231
high Confidence
Subject:
VIN_2
(Disease classification)
→
is_defined_by
→
Object:
nuclear_atypia
(Nuclear abnormalities)
Original: VIN 2#is defined by#nuclear atypia and mitotic figures confined to the basal half of the epithelium
#20230
high Confidence
Subject:
refractile_keratin_clumps
(Cell morphology)
→
provides_clue_for
→
Object:
diagnosis_of_pilomatrixoma
(Disease diagnosis)
Original: prominent nucleoli in basaloid cells and refractile keratin clumps#were useful clues in#diagnosis of pilomatrixoma
#20229
high Confidence
Subject:
prominent_nucleoli_in_basaloid_cells
(Cell morphology)
→
provides_clue_for
→
Object:
diagnosis_of_pilomatrixoma
(Disease diagnosis)
Original: prominent nucleoli in basaloid cells and refractile keratin clumps#were useful clues in#diagnosis of pilomatrixoma
#20226
high Confidence
Subject:
Tumor
(Tumor tissue)
→
showed_immunoreactivity_with
→
Object:
cytokeratin_8/18
(Cell markers)
Original: Tumor#showed immunoreactivity with#cytokeratin 8/18/ cytokeratin 18/ cytokeratin 19/ vimentin
#20225
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
were_positive_for
→
Object:
cytokeratin_19
(Cell markers)
Original: Tumor cells#were positive for#cytokeratin 19 but negative for glypican 3
#20220
high Confidence
Subject:
severe_nuclear_atypia
(Abnormal nuclear morphology)
→
is_diagnosed_as
→
Object:
carcinoma_in_situ
(Tumor type)
Original: Severe nuclear atypia in the mucosa#is diagnosed as#carcinoma in situ (CIS)
#20218
high Confidence
Subject:
abnormal_cells
(Tumor cell type)
→
have
→
Object:
chromosomal_translocation_t(2;5)(p23;q35)
(Chromosomal mutations)
Original: Abnormal cells#have#a characteristic chromosomal translocation t(2;5)(p23;q35)
#20217
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
showed_positive_staining_with
→
Object:
ALK
(Protein markers)
Original: Malignant cells#showed#positive staining with CD30/ ALK/ epithelial membrane antigen/ and beta-HCG
#20216
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
showed_positive_staining_with
→
Object:
CD30
(Protein markers)
Original: Malignant cells#showed#positive staining with CD30/ ALK/ epithelial membrane antigen/ and beta-HCG
#20210
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CD3
(T cell markers)
Original: tumor cells#are#negative for CD3
#20209
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
contain
→
Object:
visible_nucleoli
(Cell morphology)
Original: tumor cells#contain#visible nucleoli
#20208
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
significant_atypia
(Cell morphology)
Original: tumor cells#exhibit#large nuclei/ prominent nucleoli/ and significant atypia
#20207
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
prominent_nucleoli
(Cell morphology)
Original: tumor cells#exhibit#large nuclei/ prominent nucleoli/ and significant atypia
#20206
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
large_nuclei
(Cell morphology)
Original: tumor cells#exhibit#large nuclei/ prominent nucleoli/ and significant atypia
#20203
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
exhibit
→
Object:
atypical_mitotic_figures
(Cell morphology)
Original: neoplastic cells#exhibit#prominent nucleoli/ hyperchromatic nuclei/ and atypical mitotic figures
#20202
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
exhibit
→
Object:
hyperchromatic_nuclei
(Cell morphology)
Original: neoplastic cells#exhibit#prominent nucleoli/ hyperchromatic nuclei/ and atypical mitotic figures
#20201
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
exhibit
→
Object:
prominent_nucleoli
(Cell morphology)
Original: neoplastic cells#exhibit#prominent nucleoli/ hyperchromatic nuclei/ and atypical mitotic figures
#20200
high Confidence
Subject:
pseudohyperplastic_areas
(Histological structure)
→
lack
→
Object:
basal_cells
(Cell Type)
Original: pseudohyperplastic areas#lack#basal cells
#20199
high Confidence
Subject:
Intravascular_lymphomatosis
(Tumor)
→
presents_with
→
Object:
dermatologic_involvement
(Skin involvement)
Original: Intravascular lymphomatosis#presents with#central nervous system and dermatologic involvement
#20198
high Confidence
Subject:
Intravascular_lymphomatosis
(Tumor)
→
presents_with
→
Object:
central_nervous_system_involvement
(Nervous system involvement)
Original: Intravascular lymphomatosis#presents with#central nervous system and dermatologic involvement
#20197
high Confidence
Subject:
RDD_histiocytes
(Histiocytes)
→
show_positive_immunostaining_for
→
Object:
S100
(Protein markers)
Original: RDD histiocytes#show positive immunostaining for#CD68/ CD163/ S100/ OCT-2/ Cyclin D1
#20196
high Confidence
Subject:
RDD_histiocytes
(Histiocytes)
→
show_positive_immunostaining_for
→
Object:
CD163
(Protein markers)
Original: RDD histiocytes#show positive immunostaining for#CD68/ CD163/ S100/ OCT-2/ Cyclin D1
#20195
high Confidence
Subject:
RDD_histiocytes
(Histiocytes)
→
show_positive_immunostaining_for
→
Object:
CD68
(Protein markers)
Original: RDD histiocytes#show positive immunostaining for#CD68/ CD163/ S100/ OCT-2/ Cyclin D1
#20178
high Confidence
Subject:
spherical_hyaline_cytoplasmic_inclusions
(Cellular substructure)
→
are_immunoreactive_for
→
Object:
sarcomeric_actin
(Cytoskeletal proteins)
Original: Spherical hyaline cytoplasmic inclusions#are immunoreactive for#vimentin and sarcomeric actin
#20177
high Confidence
Subject:
spherical_hyaline_cytoplasmic_inclusions
(Cellular substructure)
→
are_immunoreactive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Spherical hyaline cytoplasmic inclusions#are immunoreactive for#vimentin and sarcomeric actin
#20170
high Confidence
Subject:
tumor_cell
(Tumor cells)
→
shows
→
Object:
strong_diffuse_cytoplasmic_immunolabeling_for_vimentin
(Protein expression)
Original: tumor cells#show#strong and diffuse cytoplasmic immunolabeling for vimentin and other markers
#20169
high Confidence
Subject:
fine-needle_aspiration_cytology
(Detection Methods)
→
is_useful_for
→
Object:
diagnosis_of_distal_extremity_lesions
(Disease diagnosis)
Original: Fine-needle aspiration cytology#has been shown to be useful in#diagnosis of distal extremity lesions
#20168
high Confidence
Subject:
Histologic_diagnosis
(Histological diagnosis)
→
revealed
→
Object:
sclerosing_ductal_papilloma_with_atypical_apocrine_metaplasia
(Disease diagnosis)
Original: Histologic diagnosis#revealed#sclerosing ductal papilloma with atypical apocrine metaplasia
#20167
high Confidence
Subject:
hyperbasophilic_cells
(Cell Type)
→
confirms
→
Object:
PPBL
(disease)
Original: presence of monocytoid or hyperbasophilic cells#confirms#PPBL
#20166
high Confidence
Subject:
monocytoid_cells
(Cell Type)
→
confirms
→
Object:
PPBL
(disease)
Original: presence of monocytoid or hyperbasophilic cells#confirms#PPBL
#20164
high Confidence
Subject:
malignant cells
(Tumor cells)
→
indicate
→
Object:
prostatic origin
(Organization Source)
Original: cytologic features#indicated#prostatic origin by large and often multiple nucleoli
#20163
high Confidence
Subject:
FNA_biopsy_smears
(Cytology specimens)
→
were_reviewed_in
→
Object:
fibrocystic_disease
(Benign lesions)
Original: FNA biopsy smears#were reviewed from#62 fibroadenoma/ 60 ductal carcinoma/ and 42 fibrocystic disease subjects
#20162
high Confidence
Subject:
FNA_biopsy_smears
(Cytology specimens)
→
were_reviewed_in
→
Object:
ductal_carcinoma
(Malignant tumors)
Original: FNA biopsy smears#were reviewed from#62 fibroadenoma/ 60 ductal carcinoma/ and 42 fibrocystic disease subjects
#20161
high Confidence
Subject:
FNA_biopsy_smears
(Cytology specimens)
→
were_reviewed_in
→
Object:
fibroadenoma
(Benign tumors)
Original: FNA biopsy smears#were reviewed from#62 fibroadenoma/ 60 ductal carcinoma/ and 42 fibrocystic disease subjects
#20156
high Confidence
Subject:
lymphoid_cells
(Lymphocytes)
→
are_immunoreactive_to
→
Object:
Ki-67
(Proliferation markers)
Original: lymphoid cells#are immunoreactive to#CD20/ CD3/ CD4/ CD56/ TIA-1/ EBER/ Ki-67
#20155
high Confidence
Subject:
lymphoid_cells
(Lymphocytes)
→
are_immunoreactive_to
→
Object:
EBER
(Nucleic acid markers)
Original: lymphoid cells#are immunoreactive to#CD20/ CD3/ CD4/ CD56/ TIA-1/ EBER/ Ki-67
#20154
high Confidence
Subject:
lymphoid_cells
(Lymphocytes)
→
are_immunoreactive_to
→
Object:
TIA-1
(Immune markers)
Original: lymphoid cells#are immunoreactive to#CD20/ CD3/ CD4/ CD56/ TIA-1/ EBER/ Ki-67
#20153
high Confidence
Subject:
lymphoid_cells
(Lymphocytes)
→
are_immunoreactive_to
→
Object:
CD56
(Immune markers)
Original: lymphoid cells#are immunoreactive to#CD20/ CD3/ CD4/ CD56/ TIA-1/ EBER/ Ki-67
#20152
high Confidence
Subject:
lymphoid_cells
(Lymphocytes)
→
are_immunoreactive_to
→
Object:
CD4
(Immune markers)
Original: lymphoid cells#are immunoreactive to#CD20/ CD3/ CD4/ CD56/ TIA-1/ EBER/ Ki-67
#20151
high Confidence
Subject:
lymphoid_cells
(Lymphocytes)
→
are_immunoreactive_to
→
Object:
CD3
(Immune markers)
Original: lymphoid cells#are immunoreactive to#CD20/ CD3/ CD4/ CD56/ TIA-1/ EBER/ Ki-67
#20150
high Confidence
Subject:
lymphoid_cells
(Lymphocytes)
→
are_immunoreactive_to
→
Object:
CD20
(Immune markers)
Original: lymphoid cells#are immunoreactive to#CD20/ CD3/ CD4/ CD56/ TIA-1/ EBER/ Ki-67
#20149
high Confidence
Subject:
HS-SY-II_cells
(Human tumor cell lines)
→
express
→
Object:
cytokeratin
(Cytokeratin)
Original: HS-SY-II cells#express#vimentin and cytokeratin by immunohistochemistry
#20148
high Confidence
Subject:
HS-SY-II_cells
(Human tumor cell lines)
→
express
→
Object:
vimentin
(Intermediate filament protein)
Original: HS-SY-II cells#express#vimentin and cytokeratin by immunohistochemistry
#20145
high Confidence
Subject:
FNA_smear
(Cytology)
→
is_useful_for
→
Object:
cytologic_differential_diagnosis
(Diagnostic Process)
Original: FNA smears#together with#HMCK immunohistochemistry can be useful for the cytologic differential diagnosis of renal tumors
#20144
high Confidence
Subject:
all_cases
(Case Collection)
→
had
→
Object:
histologic_confirmation_of_diagnosis
(Diagnostic Process)
Original: all cases#had#histologic confirmation of the diagnosis
#20143
high Confidence
Subject:
SPTCL
(disease)
→
presents_with
→
Object:
hemophagocytic_lymphohistiocytosis
(disease)
Original: SPTCL#presents with#hemophagocytic lymphohistiocytosis and skin lesions
#20141
high Confidence
Subject:
stereotactic_biopsy
(Diagnostic techniques)
→
diagnosed
→
Object:
lymphoma
(disease)
Original: Stereotactic biopsy#diagnosed#lymphoma
#20132
high Confidence
Subject:
Tumor
(Tumor tissue)
→
is_diagnosed_as
→
Object:
acinar_cell_carcinoma_of_pancreas
(Neoplastic diseases)
Original: Tumor#is diagnosed as#acinar cell carcinoma of the pancreas
#20124
high Confidence
Subject:
congenital_malignant_extrarenal_rhabdoid_tumor
(Tumor)
→
is_located_in
→
Object:
right_paratesticular_area
(Anatomical location)
Original: congenital malignant extrarenal rhabdoid tumor#is located in#right paratesticular area
#20120
high Confidence
Subject:
Resected_tumor_tissue
(Tumor tissue)
→
showed
→
Object:
immunoreactivity_for_somatostatin
(Protein expression characteristics)
Original: Resected tumor tissue#showed#immunoreactivity for alpha-fetoprotein/ neuron-specific enolase/ and somatostatin
#20119
high Confidence
Subject:
Resected_tumor_tissue
(Tumor tissue)
→
showed
→
Object:
immunoreactivity_for_neuron_specific_enolase
(Protein expression characteristics)
Original: Resected tumor tissue#showed#immunoreactivity for alpha-fetoprotein/ neuron-specific enolase/ and somatostatin
#20118
high Confidence
Subject:
Resected_tumor_tissue
(Tumor tissue)
→
showed
→
Object:
immunoreactivity_for_alpha_fetoprotein
(Protein expression characteristics)
Original: Resected tumor tissue#showed#immunoreactivity for alpha-fetoprotein/ neuron-specific enolase/ and somatostatin
#20111
high Confidence
Subject:
peripheral_primitive_neuroectodermal_tumor
(Rare tumors)
→
is
→
Object:
rare_diagnostically_challenging_tumor_in_CNS
(Rare tumor characteristics)
Original: Meningeal Ewing Sarcoma (ES)/peripheral primitive neuroectodermal tumor (pPNET)#is#a rare diagnostically challenging tumor in the CNS
#20110
high Confidence
Subject:
meningeal_ewing_sarcoma
(Rare tumors)
→
is
→
Object:
rare_diagnostically_challenging_tumor_in_CNS
(Rare tumor characteristics)
Original: Meningeal Ewing Sarcoma (ES)/peripheral primitive neuroectodermal tumor (pPNET)#is#a rare diagnostically challenging tumor in the CNS
#20106
high Confidence
Subject:
morphologic_features
(Histological characteristics)
→
are_consistent_with
→
Object:
rhabdoid_meningioma
(Disease diagnosis)
Original: Morphologic features#are consistent with#diagnosis of rhabdoid meningioma
#20104
high Confidence
Subject:
gastric_glomus_tumor
(Tumor type)
→
is_diagnosed_by
→
Object:
fine_needle_aspiration_of_stomach
(Diagnostic Methods)
Original: gastric glomus tumor#is diagnosed by#fine needle aspiration of the stomach
#20100
high Confidence
Subject:
neoplastic_cell
(Tumor cells)
→
is_positive_for
→
Object:
epithelial_membrane_antigen
(protein)
Original: neoplastic cells#are positive for#cytokeratin and epithelial membrane antigen
#20099
high Confidence
Subject:
neoplastic_cell
(Tumor cells)
→
is_positive_for
→
Object:
cytokeratin
(protein)
Original: neoplastic cells#are positive for#cytokeratin and epithelial membrane antigen
#20045
high Confidence
Subject:
LC3_proteins
(Autophagy-related proteins)
→
are_used_as
→
Object:
major_markers_of_autophagy
(Molecular markers)
Original: endogenous LC3 proteins#are used as#major markers of autophagy
#20021
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
showed_positive_staining_with
→
Object:
beta-HCG
(Hormone markers)
Original: Malignant cells#showed#positive staining with CD30/ ALK/ epithelial membrane antigen/ and beta-HCG
#20020
high Confidence
Subject:
malignant_cells
(Tumor cells)
→
showed_positive_staining_with
→
Object:
epithelial_membrane_antigen
(Protein markers)
Original: Malignant cells#showed#positive staining with CD30/ ALK/ epithelial membrane antigen/ and beta-HCG
#20009
high Confidence
Subject:
SPTCL
(disease)
→
presents_with
→
Object:
skin_lesions
(Clinical symptoms)
Original: SPTCL#presents with#hemophagocytic lymphohistiocytosis and skin lesions
#19967
middle Confidence
Subject:
cytofluorometric_DNA_analysis
(Molecular detection technology)
→
is_useful_for
→
Object:
malignant_grade_evaluation
(Tumor grade assessment)
Original: Combined cytofluorometric DNA analysis/ AgNOR count/ and p53 immunoreactivity#might be useful for#evaluating malignant grade of salivary gland tumors
#19962
middle Confidence
Subject:
lactate_dehydrogenase
(Enzymes)
→
increased_in
→
Object:
serum_of_Pulmonary_intravascular_large_B_cell_lymphoma_patients
(serum)
Original: Serum lactate dehydrogenase level#increased#in 7/8 patients
#19953
middle Confidence
Subject:
Brush_technique
(Cytobrush technique)
→
is_accurate_for
→
Object:
cytodiagnosis_of_lung_cancer
(Cytological diagnosis of lung cancer)
Original: Brush technique#is accurate for#cytodiagnosis of lung cancer
#19952
middle Confidence
Subject:
diagnostic_criteria
(Diagnostic criteria)
→
diagnose
→
Object:
schwannoma
(Tumor type)
Original: 5 criteria#diagnose#schwannoma with sensitivity/ specificity/ positive predictive value/ and negative predictive value
#19951
middle Confidence
Subject:
cytological_findings
(Cytological characteristics)
→
aids_in
→
Object:
preoperative_diagnosis_of_adenosarcoma
(Diagnostic Process)
Original: Cytological findings#aid in#correct preoperative diagnosis of adenosarcoma
#19950
middle Confidence
Subject:
intraoperative_squash_cytologic_examination
(Intraoperative compression cytology)
→
is_suggested_as
→
Object:
useful_initial_approach_in_metastatic_brain_tumor_diagnosis
(Diagnostic strategy)
Original: Intraoperative squash cytologic examination#was suggested as#a useful initial approach in metastatic brain tumor diagnosis
#19949
middle Confidence
Subject:
cytopathological_features
(Cytopathological characteristics)
→
favor
→
Object:
CASTLE_diagnosis
(Disease diagnosis)
Original: Cytopathological features#favored#CASTLE diagnosis
#19947
middle Confidence
Subject:
clinical_features
(Clinical characteristics)
→
may_give_clues_to
→
Object:
detection_of_ALK-positive_cases
(Detection behavior)
Original: Clinical features#may give clues to#detection of ALK-positive cases
#19945
middle Confidence
Subject:
Fine-needle_aspiration
(Cytology)
→
plays_vital_role_in
→
Object:
detection_of_melanoma
(Diagnostic Process)
Original: Fine-needle aspiration (FNA)#plays#a vital role in detection of melanoma
#19937
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
factor_VIII-related_antigen
(Diagnostic markers)
Original: tumor cells#are positive for#factor VIII-related antigen
#19922
middle Confidence
Subject:
enlarged_nucleoli
(Organelles)
→
are
→
Object:
important_cytological_criteria_for_malignant_changes
(Diagnostic criteria)
Original: enlarged nucleoli#are#important cytological criteria for defining malignant changes
#19915
middle Confidence
Subject:
SDHD
(Protein coding genes)
→
involved_less_in
→
Object:
SDH_deficient_RCC
(Disease phenotype)
Original: Gene alterations#involve less#SDHC/ SDHA/ and SDHD subunits in SDH-deficient RCC
#19914
middle Confidence
Subject:
SDHA
(Protein coding genes)
→
involved_less_in
→
Object:
SDH_deficient_RCC
(Disease phenotype)
Original: Gene alterations#involve less#SDHC/ SDHA/ and SDHD subunits in SDH-deficient RCC
#19913
middle Confidence
Subject:
SDHC
(Protein coding genes)
→
involved_less_in
→
Object:
SDH_deficient_RCC
(Disease phenotype)
Original: Gene alterations#involve less#SDHC/ SDHA/ and SDHD subunits in SDH-deficient RCC
#19906
middle Confidence
Subject:
p53
(Tumor suppressor proteins)
→
is_biomarker_for
→
Object:
del(5q)_syndrome
(Chromosomal abnormality syndrome)
Original: Nuclear p53 staining#accumulates in#erythroid progenitor cells in DBA or del(5q) patients
#19905
middle Confidence
Subject:
p53
(Tumor suppressor proteins)
→
is_biomarker_for
→
Object:
Diamond-Blackfan_anemia
(Hereditary anemia)
Original: Nuclear p53 staining#accumulates in#erythroid progenitor cells in DBA or del(5q) patients
#19858
middle Confidence
Subject:
SNORA68
(Small nuclear RNA)
→
is_highly_expressed_in
→
Object:
TNBC
(disease)
Original: SNORA68#exhibited#high expression in TNBC and correlated with tumor size/ ki-67 level/ and TNM stage
#19845
middle Confidence
Subject:
Silver-NOR_number
(Silver stained nucleoli number)
→
differs_significantly_between
→
Object:
melanomas
(Melanoma)
Original: Silver-NOR numbers#differ significantly between#benign lesions and melanomas
#19844
middle Confidence
Subject:
Silver-NOR_number
(Silver stained nucleoli number)
→
differs_significantly_between
→
Object:
benign_lesions
(Benign lesions)
Original: Silver-NOR numbers#differ significantly between#benign lesions and melanomas
#19840
middle Confidence
Subject:
CEA
(CEA)
→
is_positive_in
→
Object:
adenoma_malignum_histologic_specimen
(Tumor tissue specimens)
Original: HIK-1083 and CEA#are positive in#histologic specimens of adenoma malignum
#19839
middle Confidence
Subject:
HIK-1083
(Glycoprotein antigen)
→
is_positive_in
→
Object:
adenoma_malignum_histologic_specimen
(Tumor tissue specimens)
Original: HIK-1083 and CEA#are positive in#histologic specimens of adenoma malignum
#19838
middle Confidence
Subject:
tumor
(Tumor tissue)
→
shows
→
Object:
perinuclear_clearing
(Perinuclear clear cells)
Original: The tumor#typically shows#papillary RCC/ type 2/ with eosinophilic large nucleoli and perinuclear clearing/haloes
#19837
middle Confidence
Subject:
tumor
(Tumor tissue)
→
shows
→
Object:
eosinophilic_large_nucleoli
(Nuclear morphology)
Original: The tumor#typically shows#papillary RCC/ type 2/ with eosinophilic large nucleoli and perinuclear clearing/haloes
#19820
middle Confidence
Subject:
Cytological_features
(Cytological characteristics)
→
are_important_for
→
Object:
diagnosis_of_deciduoid_mesothelioma
(Disease diagnosis)
Original: Cytological features#are important for#diagnosis of deciduoid mesothelioma
#19812
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
melan-A
(Protein markers)
Original: Tumor cells#were positive for#vimentin/ SF-1/ inhibin α/ and melan-A
#19811
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
inhibin_α
(Protein markers)
Original: Tumor cells#were positive for#vimentin/ SF-1/ inhibin α/ and melan-A
#19810
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
SF-1
(Protein markers)
Original: Tumor cells#were positive for#vimentin/ SF-1/ inhibin α/ and melan-A
#19809
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
vimentin
(Protein markers)
Original: Tumor cells#were positive for#vimentin/ SF-1/ inhibin α/ and melan-A
#19805
middle Confidence
Subject:
cytologic_morphometric_parameters
(Diagnostic parameters)
→
assist_in
→
Object:
diagnosis_of_thyroid_lesions
(Diagnostic Process)
Original: 18 cytologic morphometric parameters#assist in#diagnosis of thyroid lesions
#19803
middle Confidence
Subject:
2SC
(Protein modification markers)
→
overexpressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#show#overexpression for 2SC and reduced expression of FH
#19789
middle Confidence
Subject:
Neoplasia
(Disease Entity)
→
classified_as
→
Object:
multicentric_lymphohistiocytic_lymphoma
(Disease Entity)
Original: The neoplasia#is classified as#multicentric lymphohistiocytic lymphoma
#19788
middle Confidence
Subject:
Synovial_sarcoma_cases
(Tumor Cases)
→
are_initially_diagnosed_as
→
Object:
adult_rhabdoid_tumors
(Tumor type)
Original: Synovial sarcoma cases#are initially diagnosed as#adult rhabdoid tumors
#19771
middle Confidence
Subject:
MPNSTs
(Tumor type)
→
distinguished_from
→
Object:
neurofibromas
(Tumor type)
Original: MPNSTs#are distinguished from#benign schwannomas and neurofibromas based on quantitative parameters
#19770
middle Confidence
Subject:
MPNSTs
(Tumor type)
→
distinguished_from
→
Object:
benign_schwannomas
(Tumor type)
Original: MPNSTs#are distinguished from#benign schwannomas and neurofibromas based on quantitative parameters
#19769
middle Confidence
Subject:
AgNOR_technique
(Molecular detection methods)
→
correlates_with
→
Object:
histological_malignancy_grade
(Malignancy grading)
Original: AgNOR technique#correlates with#histological malignancy grade in bone NHL
#19756
middle Confidence
Subject:
AgNOR_analysis
(Nucleolar organizer region analysis)
→
aids_in
→
Object:
diagnosis_of_hydatidiform_mole
(Diagnosis of hydatidiform mole)
Original: AgNOR analyses#aid in#diagnosis and classification of hydatidiform moles
#19743
middle Confidence
Subject:
p53
(Tumor suppressor proteins)
→
identifies
→
Object:
residual_atypical_intraepithelial_cells
(Abnormal cells)
Original: p53#identifies#residual atypical intraepithelial cells
#19731
middle Confidence
Subject:
p53_immunoreactivity
(Protein expression phenotype)
→
is_useful_for
→
Object:
malignant_grade_evaluation
(Tumor grade assessment)
Original: Combined cytofluorometric DNA analysis/ AgNOR count/ and p53 immunoreactivity#might be useful for#evaluating malignant grade of salivary gland tumors
#19730
middle Confidence
Subject:
AgNOR_count
(Molecular detection indicators)
→
is_useful_for
→
Object:
malignant_grade_evaluation
(Tumor grade assessment)
Original: Combined cytofluorometric DNA analysis/ AgNOR count/ and p53 immunoreactivity#might be useful for#evaluating malignant grade of salivary gland tumors
#19716
middle Confidence
Subject:
telomerase_activity
(Telomerase activity)
→
differentiates_between
→
Object:
malignant_tumors_in_dogs
(Malignant tumors)
Original: telomerase activity#differentiates between#benign and malignant tumors in dogs but requires additional markers
#19715
middle Confidence
Subject:
telomerase_activity
(Telomerase activity)
→
differentiates_between
→
Object:
benign_tumors_in_dogs
(Benign tumors)
Original: telomerase activity#differentiates between#benign and malignant tumors in dogs but requires additional markers
#19697
middle Confidence
Subject:
proliferative_activity_marker
(Molecular markers)
→
shows
→
Object:
statistically_significant_difference_between_benign_tumors
(Tumor type)
Original: proliferative activity markers#show#statistically significant difference between malignant and benign tumors
#19696
middle Confidence
Subject:
proliferative_activity_marker
(Molecular markers)
→
shows
→
Object:
statistically_significant_difference_between_malignant_tumors
(Tumor type)
Original: proliferative activity markers#show#statistically significant difference between malignant and benign tumors
#19694
middle Confidence
Subject:
Papillary_tumors
(Tumor type)
→
exhibit
→
Object:
no_histological_evidence_of_malignancy
(Histological phenotype)
Original: Papillary tumors#exhibit#no histological evidence of malignancy
#19689
middle Confidence
Subject:
nucleolar_staining
(Histological features)
→
correlates_with
→
Object:
nuclear_grade
(Pathological grading)
Original: Nucleolar staining#correlated with#nuclear grade
#19672
middle Confidence
Subject:
excisional_biopsy
(Tissue biopsy)
→
demonstrated
→
Object:
metastatic_Merkel_cell_carcinoma
(disease)
Original: Excisional biopsy#demonstrated#metastatic Merkel cell carcinoma (MCC)
#19660
middle Confidence
Subject:
ancillary_studies
(Testing)
→
exclude
→
Object:
myxoid_neural_tumors
(disease)
Original: ancillary studies#exclude#myxoid neural tumors
#19659
middle Confidence
Subject:
ancillary_studies
(Testing)
→
exclude
→
Object:
myxoid_liposarcoma
(disease)
Original: ancillary studies#exclude#myxoid liposarcoma
#19658
middle Confidence
Subject:
ancillary_studies
(Testing)
→
exclude
→
Object:
myxoid_rhabdomyosarcoma
(disease)
Original: ancillary studies#exclude#myxoid rhabdomyosarcoma
#19655
middle Confidence
Subject:
sarcomatoid_appearance_of_cardiac_lesion
(Tumor tissue characteristics)
→
raises_differential_diagnosis_with
→
Object:
primary_cardiac_sarcoma
(Tumor)
Original: The sarcomatoid appearance of the cardiac lesion#raises#the problem of differential diagnosis with primary cardiac sarcoma
#19654
middle Confidence
Subject:
Tumors
(Tumor tissue)
→
show
→
Object:
Intense_nuclear_positivity_for_TFE3
(Protein expression)
Original: Tumors#show#strong cytoplasmic expression of HMB-45 and intense nuclear positivity for TFE3
#19653
middle Confidence
Subject:
Tumors
(Tumor tissue)
→
show
→
Object:
Strong_cytoplasmic_expression_of_HMB-45
(Protein expression)
Original: Tumors#show#strong cytoplasmic expression of HMB-45 and intense nuclear positivity for TFE3
#19641
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
prominent_nucleoli
(Cell morphology)
Original: tumor cells#had#clear or eosinophilic cytoplasm and prominent nucleoli/ arranged in alveolar structures surrounded by delicate blood sinuses
#19640
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
eosinophilic_cytoplasm
(Cell morphology)
Original: tumor cells#had#clear or eosinophilic cytoplasm and prominent nucleoli/ arranged in alveolar structures surrounded by delicate blood sinuses
#19639
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
clear_cytoplasm
(Cell morphology)
Original: tumor cells#had#clear or eosinophilic cytoplasm and prominent nucleoli/ arranged in alveolar structures surrounded by delicate blood sinuses
#19635
middle Confidence
Subject:
MMCA
(Molecular detection technology)
→
was_applied_for
→
Object:
early_detection_of_cancer
(Diagnostic Applications)
Original: MMCA#was applied for#early detection of cancer cases with a limited number of suspicious cells
#19633
middle Confidence
Subject:
AgNOR_distribution_score
(Molecular staining scores)
→
distinguishes
→
Object:
follicular_carcinoma
(Tumor tissue)
Original: AgNOR distribution score#proved the most valuable diagnostic criterion for#cytomorphological differentiation between follicular adenoma and carcinoma of the thyroid
#19632
middle Confidence
Subject:
AgNOR_distribution_score
(Molecular staining scores)
→
distinguishes
→
Object:
follicular_adenoma
(Tumor tissue)
Original: AgNOR distribution score#proved the most valuable diagnostic criterion for#cytomorphological differentiation between follicular adenoma and carcinoma of the thyroid
#19631
middle Confidence
Subject:
AgNOR_distribution_score
(Molecular staining scores)
→
serves_as
→
Object:
diagnostic_criterion_for_cytomorphological_differentiation
(Diagnostic criteria)
Original: AgNOR distribution score#proved the most valuable diagnostic criterion for#cytomorphological differentiation between follicular adenoma and carcinoma of the thyroid
#19623
middle Confidence
Subject:
cervical_smears
(Cytology samples)
→
are_helpful_for
→
Object:
early_diagnosis_of_VGA
(Early diagnosis)
Original: cervical smears#are helpful for#early diagnosis of VGA
#19620
middle Confidence
Subject:
Targeted_next-generation_sequencing
(Molecular detection technology)
→
revealed
→
Object:
ARID1B-TFE3_gene_fusion
(Gene fusion events)
Original: Targeted next-generation sequencing#revealed#ARID1B-TFE3 gene fusion
#19619
middle Confidence
Subject:
uterine_cytology
(Cytology)
→
suggested
→
Object:
intravascular_lymphomatosis
(disease)
Original: intravascular lymphomatosis#was suspected from#uterine cytology
#19612
middle Confidence
Subject:
low-grade_squamous_lesion
(Pathological morphology)
→
detected_in
→
Object:
case
(Case)
Original: Low-grade glandular and/or squamous lesions#were detected in#nine cases
#19611
middle Confidence
Subject:
low-grade_glandular_lesion
(Pathological morphology)
→
detected_in
→
Object:
case
(Case)
Original: Low-grade glandular and/or squamous lesions#were detected in#nine cases
#19610
middle Confidence
Subject:
Cytomorphology
(Cell morphology)
→
coupled_with
→
Object:
immunophenotyping_study
(Immunophenotyping)
Original: Cytomorphology coupled with immunophenotyping study#suggested#diagnosis of low-grade B-cell lymphoma of MALT
#19591
middle Confidence
Subject:
Cytological_findings
(Cytology results)
→
correlate_with
→
Object:
histopathological_observations
(Histopathological results)
Original: Cytological findings#were correlated with#histopathological observations
#19590
middle Confidence
Subject:
Cementoblastoma
(Neoplastic diseases)
→
is_characterized_by
→
Object:
formation_of_osteocementum-like_tissue
(Tumor tissue morphology)
Original: Cementoblastoma#is characterized by#formation of osteocementum-like tissue on a tooth root
#19575
middle Confidence
Subject:
endometrial_cytology_findings
(Cytological analysis)
→
suggests
→
Object:
histological_diagnosis_of_UPSC
(Histological diagnosis)
Original: Endometrial cytology findings#accurately suggested#the histological diagnosis of UPSC
#19561
middle Confidence
Subject:
histopathological_analysis
(Diagnostic Methods)
→
revealed
→
Object:
diffusely_infiltrating_growth
(Tumor morphology)
Original: histopathological analysis#revealed#positive H3 K27M mutant protein and diffusely infiltrating growth
#19556
middle Confidence
Subject:
bone_marrow_biopsy
(Histological examination)
→
revealed
→
Object:
myeloproliferative_disorder
(Disease diagnosis)
Original: bone marrow biopsy#revealed#a myeloproliferative disorder
#19529
middle Confidence
Subject:
Cervical smear findings
(Cytology test results)
→
have_been_reported_in
→
Object:
uterine MMMT
(Tumor type)
Original: Cervical smear findings#have been reported in#uterine MMMT
#19527
middle Confidence
Subject:
focal_reactivity_with_anti-chromogranin_antibody_and_neurosecretory_granules
(Immunohistochemistry and ultrastructural examination)
→
supports
→
Object:
neuroendocrine_differentiation_for_small_neoplastic_cells
(Cell differentiation phenotype)
Original: focal reactivity with anti-chromogranin antibody and neurosecretory granules#supports#neuroendocrine differentiation for small neoplastic cells
#19515
middle Confidence
Subject:
small_medium_cell_clusters
(Cell clusters)
→
improves
→
Object:
diagnostic_specificity_for_adenocarcinoma
(Diagnostic specificity)
Original: Presence of nucleoli and small/medium cell clusters#improves#diagnostic sensitivity and specificity for adenocarcinoma
#19514
middle Confidence
Subject:
presence_of_nucleoli
(Nucleolus)
→
improves
→
Object:
diagnostic_sensitivity_for_adenocarcinoma
(Diagnostic sensitivity)
Original: Presence of nucleoli and small/medium cell clusters#improves#diagnostic sensitivity and specificity for adenocarcinoma
#19502
middle Confidence
Subject:
recurrent_alterations_in_cysts
(Molecular abnormalities)
→
provide
→
Object:
diagnosis_opportunity_using_aspirated_cyst_fluid
(Diagnostic opportunities)
Original: recurrent alterations in cysts#provide#an opportunity for diagnosis using aspirated cyst fluid
#19484
middle Confidence
Subject:
Histologic_findings_and_clinical_data
(Diagnostic Information)
→
are_consistent_with
→
Object:
splenic_lymphoma_with_circulating_villous_lymphocytes
(Disease phenotype)
Original: Histologic findings and clinical data#are consistent with#splenic lymphoma with circulating villous lymphocytes
#19474
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contained
→
Object:
IgG_gamma-type_immunoglobulin
(Immunoglobulins)
Original: Tumor cells#contained#IgG gamma-type immunoglobulin in their cytoplasm
#19473
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
showed
→
Object:
atypical_plasma_cell_morphology
(Cell morphology)
Original: Tumor cells#showed#morphology of atypical plasma cells
#19462
middle Confidence
Subject:
fine-needle_aspiration_biopsy
(Diagnostic techniques)
→
evaluates
→
Object:
breast_masses
(Disease phenotype)
Original: fine-needle aspiration biopsy#evaluates#breast masses in pregnant and lactating women
#19461
middle Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic techniques)
→
is_used_for
→
Object:
breast_masses
(Disease phenotype)
Original: fine-needle aspiration cytology#is used for#breast masses in pregnant and lactating women
#19460
middle Confidence
Subject:
tumor_cells
(Cell Type)
→
show
→
Object:
diffuse_positivity_for_vimentin
(Protein expression characteristics)
Original: tumor cells#show#diffuse positivity for vimentin
#19456
middle Confidence
Subject:
malignant_melanoma
(Malignant tumors)
→
is_diagnosed_by
→
Object:
proliferation_of_large_polygonal_cells_with_distinct_nucleoli
(Histological diagnostic features)
Original: malignant melanoma#is diagnosed by#proliferation of large polygonal cells with distinct nucleoli
#19418
middle Confidence
Subject:
Urinary_bladder_IMT
(Tumor)
→
can_mimic
→
Object:
malignancy
(Disease phenotype)
Original: Urinary bladder IMT#can mimic#malignancy
#19390
middle Confidence
Subject:
Hurthle_cells
(Tumor cell subtype)
→
exhibits
→
Object:
nuclear_features_suspicious_of_papillary_carcinoma
(Nuclear morphology)
Original: Hurthle cells#exhibit#nuclear features suspicious of papillary carcinoma
#19376
middle Confidence
Subject:
ultrasound-guided_fine_needle_aspiration
(Imaging diagnostic technology)
→
differentiations
→
Object:
hepatoblastoma
(disease)
Original: Ultrasound-guided fine needle aspiration#differentiates#pediatric HCC from hepatoblastoma
#19375
middle Confidence
Subject:
ultrasound-guided_fine_needle_aspiration
(Imaging diagnostic technology)
→
differentiations
→
Object:
pediatric_HCC
(disease)
Original: Ultrasound-guided fine needle aspiration#differentiates#pediatric HCC from hepatoblastoma
#19374
middle Confidence
Subject:
cytomorphological_features
(Cell morphological characteristics)
→
are_evaluated_in
→
Object:
pediatric_HCC
(disease)
Original: Study#evaluates#cytomorphological features of pediatric HCC
#19362
middle Confidence
Subject:
Cytologic_diagnosis
(Diagnostic Methods)
→
is_used_for
→
Object:
acute_nonlymphoid_leukemias
(Disease phenotype)
Original: Cytologic diagnosis#is used for#acute nonlymphoid leukemias
#19359
middle Confidence
Subject:
endometrial_carcinoma
(Tumor)
→
exhibits
→
Object:
prominent_nucleoli
(Nuclear morphology)
Original: Endometrial carcinoma#exhibits#nuclear enlargement/ anisokaryosis/ irregular chromatin distribution/ and prominent nucleoli
#19358
middle Confidence
Subject:
endometrial_carcinoma
(Tumor)
→
exhibits
→
Object:
irregular_chromatin_distribution
(Abnormal chromatin distribution)
Original: Endometrial carcinoma#exhibits#nuclear enlargement/ anisokaryosis/ irregular chromatin distribution/ and prominent nucleoli
#19357
middle Confidence
Subject:
endometrial_carcinoma
(Tumor)
→
exhibits
→
Object:
anisokaryosis
(Nuclear pleomorphism)
Original: Endometrial carcinoma#exhibits#nuclear enlargement/ anisokaryosis/ irregular chromatin distribution/ and prominent nucleoli
#19356
middle Confidence
Subject:
endometrial_carcinoma
(Tumor)
→
exhibits
→
Object:
nuclear_enlargement
(Nuclear morphology)
Original: Endometrial carcinoma#exhibits#nuclear enlargement/ anisokaryosis/ irregular chromatin distribution/ and prominent nucleoli
#19339
middle Confidence
Subject:
AgNOR_mean_value_�?
(Molecular marker threshold)
→
is_used_as
→
Object:
malignant_male_breast_lesions
(Malignant breast lesions)
Original: AgNOR mean value �?3#is used as#a cut-off value between benign and malignant male breast lesions
#19338
middle Confidence
Subject:
AgNOR_mean_value_�?
(Molecular marker threshold)
→
is_used_as
→
Object:
benign_male_breast_lesions
(Benign breast lesions)
Original: AgNOR mean value �?3#is used as#a cut-off value between benign and malignant male breast lesions
#19336
middle Confidence
Subject:
USP6_gene_rearrangement
(Genomic abnormalities)
→
serves_as
→
Object:
diagnostic_adjunct_in_CF
(Diagnostic Tools)
Original: USP6 gene rearrangement#may prove helpful as#a diagnostic adjunct in CF
#19334
middle Confidence
Subject:
Sequential_bronchial_brushing_smears
(Diagnostic techniques)
→
are_studied_for
→
Object:
diagnosis_of_lung_cancer
(Diagnosis conclusion)
Original: Sequential bronchial brushing smears#are studied for#diagnosis of lung cancer
#19330
middle Confidence
Subject:
clear_cell_papillary_renal_cell_carcinoma
(Tumor type)
→
resembles
→
Object:
papillary_renal_cell_carcinoma
(Tumor type)
Original: Clear cell papillary renal cell carcinoma#resembles#clear cell renal cell carcinoma and papillary renal cell carcinoma
#19329
middle Confidence
Subject:
clear_cell_papillary_renal_cell_carcinoma
(Tumor type)
→
resembles
→
Object:
clear_cell_renal_cell_carcinoma
(Tumor type)
Original: Clear cell papillary renal cell carcinoma#resembles#clear cell renal cell carcinoma and papillary renal cell carcinoma
#19328
middle Confidence
Subject:
benign_acral_naevus
(Benign pigmented nevus)
→
identification_is_important_to_avoid
→
Object:
overtreatment_of_acral_skin_lesion
(Overtreatment)
Original: Identification of benign acral naevus#is important to avoid#misdiagnoses and over-treatment of acral skin lesions
#19327
middle Confidence
Subject:
benign_acral_naevus
(Benign pigmented nevus)
→
identification_is_important_to_avoid
→
Object:
misdiagnosis_of_acral_skin_lesion
(Clinical misdiagnosis)
Original: Identification of benign acral naevus#is important to avoid#misdiagnoses and over-treatment of acral skin lesions
#19326
middle Confidence
Subject:
dysplastic_naevus
(Benign pigmented nevus)
→
shows
→
Object:
absence_of_lamellar_fibroplasia
(Tissue morphology)
Original: Histological features of acral-lentiginous naevi#are similar to#those of dysplastic naevi except for absence of anastomosing rete ridges/ cytological atypia/ and lamellar fibroplasia
#19325
middle Confidence
Subject:
dysplastic_naevus
(Benign pigmented nevus)
→
shows
→
Object:
absence_of_cytological_atypia
(Cell morphology)
Original: Histological features of acral-lentiginous naevi#are similar to#those of dysplastic naevi except for absence of anastomosing rete ridges/ cytological atypia/ and lamellar fibroplasia
#19324
middle Confidence
Subject:
dysplastic_naevus
(Benign pigmented nevus)
→
shows
→
Object:
absence_of_anastomosing_rete_ridges
(Tissue morphology)
Original: Histological features of acral-lentiginous naevi#are similar to#those of dysplastic naevi except for absence of anastomosing rete ridges/ cytological atypia/ and lamellar fibroplasia
#19323
middle Confidence
Subject:
acral-lentiginous_naevus
(Benign pigmented nevus)
→
shows
→
Object:
absence_of_lamellar_fibroplasia
(Tissue morphology)
Original: Histological features of acral-lentiginous naevi#are similar to#those of dysplastic naevi except for absence of anastomosing rete ridges/ cytological atypia/ and lamellar fibroplasia
#19322
middle Confidence
Subject:
acral-lentiginous_naevus
(Benign pigmented nevus)
→
shows
→
Object:
absence_of_cytological_atypia
(Cell morphology)
Original: Histological features of acral-lentiginous naevi#are similar to#those of dysplastic naevi except for absence of anastomosing rete ridges/ cytological atypia/ and lamellar fibroplasia
#19321
middle Confidence
Subject:
acral-lentiginous_naevus
(Benign pigmented nevus)
→
shows
→
Object:
absence_of_anastomosing_rete_ridges
(Tissue morphology)
Original: Histological features of acral-lentiginous naevi#are similar to#those of dysplastic naevi except for absence of anastomosing rete ridges/ cytological atypia/ and lamellar fibroplasia
#19320
middle Confidence
Subject:
cytologic_feature_awareness
(Diagnostic knowledge)
→
is_important_for
→
Object:
accurate_diagnosis_of_anaplastic_medulloblastoma
(Diagnostic Accuracy)
Original: Awareness of cytologic features#is important for#accurate diagnosis of anaplastic medulloblastomas in CSF specimens
#19304
middle Confidence
Subject:
FH-RCC
(Neoplastic diseases)
→
has
→
Object:
clinicopathologic_characteristics
(Disease phenotype)
Original: Study#investigated#clinicopathologic characteristics/ molecular and genetic features/ differential diagnoses/ and prognosis of fumarate hydratase-deficient renal cell carcinoma (FH-RCC)
#19295
middle Confidence
Subject:
Preoperative_Amipaque_ventriculogram
(Imaging tests)
→
showed
→
Object:
tumor_shadow_bulging_into_third_ventricle
(Imaging findings)
Original: Preoperative Amipaque ventriculogram#showed#dilation of lateral ventricles and tumor shadow bulging into third ventricle
#19294
middle Confidence
Subject:
Preoperative_Amipaque_ventriculogram
(Imaging tests)
→
showed
→
Object:
dilation_of_lateral_ventricles
(Imaging findings)
Original: Preoperative Amipaque ventriculogram#showed#dilation of lateral ventricles and tumor shadow bulging into third ventricle
#19292
middle Confidence
Subject:
Primary_thyroid-like_follicular_carcinoma
(Tumor)
→
is_a_distinctive_neoplasm_of
→
Object:
adult_renal_epithelial_cells
(Epithelial cells)
Original: Primary thyroid-like follicular carcinoma#is a distinctive neoplasm of#adult renal epithelial cells
#19288
middle Confidence
Subject:
immunocytochemistry_of_Ad4BP
(Immunohistochemistry)
→
aided_in
→
Object:
differential_diagnosis_of_carcinomas
(Diagnostic Process)
Original: immunocytochemistry of 3 beta-hydroxysteroid dehydrogenase and Ad4BP#aided in#differential diagnosis of these carcinomas
#19287
middle Confidence
Subject:
immunocytochemistry_of_3_beta-hydroxysteroid_dehydrogenase
(Immunohistochemistry)
→
aided_in
→
Object:
differential_diagnosis_of_carcinomas
(Diagnostic Process)
Original: immunocytochemistry of 3 beta-hydroxysteroid dehydrogenase and Ad4BP#aided in#differential diagnosis of these carcinomas
#19274
middle Confidence
Subject:
Cytologic_and_immunocytochemical_findings
(Test results)
→
correlated_with
→
Object:
histologic_features_of_neoplasm
(Histological characteristics)
Original: Cytologic and immunocytochemical findings#correlated with#histologic features of the neoplasm
#19273
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Cytology)
→
is_useful_for
→
Object:
diagnosis_of_mediastinal_tumors
(Disease diagnosis)
Original: Fine-needle aspiration cytology#is useful for#diagnosis of mediastinal tumors
#19265
middle Confidence
Subject:
Fine_needle_aspiration_cytology
(Diagnostic techniques)
→
is_applied_to
→
Object:
young_patients_with_noncirrhotic_livers
(Patient characteristics)
Original: Fine needle aspiration cytology#is used for#fibrolamellar hepatocellular carcinoma
#19264
middle Confidence
Subject:
radiologic_finding
(Imaging findings)
→
suggests
→
Object:
malignancy
(Disease phenotype)
Original: Radiologic findings#suggested#malignancy in 5 lesions
#19256
middle Confidence
Subject:
BCOR-CCNB3_positive_sarcoma
(Molecular classification of tumors)
→
comprises
→
Object:
angulated_nuclei
(Nuclear characteristics)
Original: BCOR-CCNB3-positive sarcomas#comprise#diffusely arranged/ round to oval to short spindly cells with angulated nuclei
#19255
middle Confidence
Subject:
Lymphoepithelial_carcinoma
(Tumor type)
→
is_common_in
→
Object:
nasopharynx
(Anatomical location)
Original: Lymphoepithelial carcinoma#is common in#nasopharynx
#19252
middle Confidence
Subject:
Preoperative_diagnosis_of_malignant_hepatic_vascular_tumor
(Diagnostic Process)
→
is_possible_by
→
Object:
aspiration_cytology
(Diagnostic Methods)
Original: Preoperative diagnosis of malignant hepatic vascular tumor#is possible by#aspiration cytology
#19251
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_diagnosed_by
→
Object:
Pleomorphism
(Cytological characteristics)
Original: Malignancy#is diagnosed by#presence of high mitotic rate/ large nucleoli/ necrosis/ spindling and pleomorphism
#19250
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_diagnosed_by
→
Object:
spindling
(Cytological characteristics)
Original: Malignancy#is diagnosed by#presence of high mitotic rate/ large nucleoli/ necrosis/ spindling and pleomorphism
#19249
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_diagnosed_by
→
Object:
Necrosis
(Histological characteristics)
Original: Malignancy#is diagnosed by#presence of high mitotic rate/ large nucleoli/ necrosis/ spindling and pleomorphism
#19248
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_diagnosed_by
→
Object:
large_nucleoli
(Cytological characteristics)
Original: Malignancy#is diagnosed by#presence of high mitotic rate/ large nucleoli/ necrosis/ spindling and pleomorphism
#19247
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_diagnosed_by
→
Object:
high_mitotic_rate
(Cytological characteristics)
Original: Malignancy#is diagnosed by#presence of high mitotic rate/ large nucleoli/ necrosis/ spindling and pleomorphism
#19246
middle Confidence
Subject:
Cells_with_round_nuclei_and_prominent_nucleoli
(Cell morphology)
→
were_helpful_in_detecting
→
Object:
yolk_sac_tumor
(Tumor type)
Original: Cells with round nuclei and prominent nucleoli#were helpful in detecting#dysgerminoma and yolk sac tumours
#19245
middle Confidence
Subject:
Cells_with_round_nuclei_and_prominent_nucleoli
(Cell morphology)
→
were_helpful_in_detecting
→
Object:
dysgerminoma
(Tumor type)
Original: Cells with round nuclei and prominent nucleoli#were helpful in detecting#dysgerminoma and yolk sac tumours
#19242
middle Confidence
Subject:
medium_sized_lymphocytes
(Lymphocytes)
→
show_follicular_neoplastic_proliferation
→
Object:
follicular_lymphoma_medium_sized_cell_type
(Disease phenotype)
Original: Follicular neoplastic proliferation of medium-sized lymphocytes#is observed in#follicular lymphoma/ medium-sized cell type
#19241
middle Confidence
Subject:
medium_sized_lymphocytes
(Lymphocytes)
→
show_diffuse_neoplastic_proliferation
→
Object:
diffuse_lymphoma_medium_sized_cell_type
(Disease phenotype)
Original: Diffuse neoplastic proliferation of medium-sized lymphocytes#is observed in#diffuse lymphoma/ medium-sized cell type
#19240
middle Confidence
Subject:
Ultrastructural features
(Ultrastructural characteristics of cells)
→
characterize
→
Object:
splenic lymphoma with circulating lymphocytes
(disease)
Original: Ultrastructural features#characterize#splenic lymphoma with circulating lymphocytes
#19174
middle Confidence
Subject:
CD2
(Immune receptor proteins)
→
might_be
→
Object:
novel_biomarker_for_immune_efficacy
(Biomarkers)
Original: CD2#might be#a novel biomarker to predict immune efficacy
#19063
middle Confidence
Subject:
ALK1
(Monoclonal antibodies)
→
labels
→
Object:
CD30+_ALCL_cases
(Tumor Cases)
Original: Antibody ALK1#labeled#53.4% of CD30+ ALCL cases
#18917
middle Confidence
Subject:
AgNOR
(Nucleolar Organizing Region-associated Protein)
→
is_used_as
→
Object:
indicator_of_cell_proliferation
(Cell proliferation markers)
Original: AgNOR#is used as#indicator of cell proliferation in rat colon carcinogenesis
#18916
middle Confidence
Subject:
PIN_changes
(Prostatic intraepithelial neoplasia)
→
provides
→
Object:
prostate_biomarkers
(Diagnostic markers)
Original: PIN changes#provide#prostate biomarkers with high correlation to cancer
#18915
middle Confidence
Subject:
argyrophilic_proteins_from_NORs
(Nucleolar Organizing Region-associated Protein)
→
is_used_as
→
Object:
index_of_maturity_degree
(Organizational Maturity Indicators)
Original: expression of argyrophilic proteins from NORs#is used as#index of maturity degree of adrenal tumors
#18901
middle Confidence
Subject:
AgNOR morphometric analysis
(Molecular detection technology)
→
is_used_for
→
Object:
Differential diagnosis of ovarian tumors
(Diagnostic Process)
Original: AgNOR morphometry analysis#was used for#differential diagnosis of ovarian tumors
#18898
middle Confidence
Subject:
AgNORs
(Nucleolar organizing region)
→
shows_significant_difference_between
→
Object:
malignant_tumors
(Malignant tumors)
Original: Difference in AgNORs#was significant between#benign and malignant tumors
#18897
middle Confidence
Subject:
AgNORs
(Nucleolar organizing region)
→
shows_significant_difference_between
→
Object:
benign_tumors
(Benign tumors)
Original: Difference in AgNORs#was significant between#benign and malignant tumors
#18819
middle Confidence
Subject:
features
(Pathological characteristics)
→
discriminate
→
Object:
tubular_carcinoma
(Tumor diseases)
Original: features#discriminate#tubular carcinoma from benign conditions
#18813
middle Confidence
Subject:
CD5_positive_diffuse_large_B-cell_lymphoma
(Disease subtype)
→
involves
→
Object:
bone_marrow
(organ)
Original: CD5 positive diffuse large B-cell lymphomas#involved#bone marrow in Korean patients
#18809
middle Confidence
Subject:
TFE3_gene_fusion
(Gene fusion)
→
can_arise_in
→
Object:
kidney
(organ)
Original: Pathologists#should recognize#PEComa with TFE3 gene fusion can arise in the kidney
#18808
middle Confidence
Subject:
TFE3
(Transcription Factors)
→
gene_break_detected_in
→
Object:
renal_eAML/PEComa
(Tumor type)
Original: This case#is#the first reported renal eAML/PEComa with a TFE3 gene break
#18780
middle Confidence
Subject:
CD99_staining_pattern
(Protein expression characteristics)
→
indicates
→
Object:
virus_status_of_Merkel_cell_carcinoma
(Disease classification)
Original: CD99 staining pattern#indicates#virus status of Merkel cell carcinoma
#18773
middle Confidence
Subject:
tumor
(Tumor)
→
is_recognized_in
→
Object:
mesenchymal_tumor
(Tumor type)
Original: tumors#are recognized in#a wide heterogeneous group of carcinoma/ melanoma/ mesothelioma/ and mesenchymal tumors
#18772
middle Confidence
Subject:
tumor
(Tumor)
→
is_recognized_in
→
Object:
mesothelioma
(Tumor type)
Original: tumors#are recognized in#a wide heterogeneous group of carcinoma/ melanoma/ mesothelioma/ and mesenchymal tumors
#18771
middle Confidence
Subject:
tumor
(Tumor)
→
is_recognized_in
→
Object:
melanoma
(Tumor type)
Original: tumors#are recognized in#a wide heterogeneous group of carcinoma/ melanoma/ mesothelioma/ and mesenchymal tumors
#18770
middle Confidence
Subject:
tumor
(Tumor)
→
is_recognized_in
→
Object:
carcinoma
(Tumor type)
Original: tumors#are recognized in#a wide heterogeneous group of carcinoma/ melanoma/ mesothelioma/ and mesenchymal tumors
#18758
middle Confidence
Subject:
cohesive_epithelioid_cells
(Cell Type)
→
show
→
Object:
ovoid_nuclei
(Nuclear morphology)
Original: Smear characteristics#include#cohesive epithelioid cells with moderate cytoplasm and ovoid nuclei
#18757
middle Confidence
Subject:
cohesive_epithelioid_cells
(Cell Type)
→
show
→
Object:
moderate_cytoplasm
(Cell morphology)
Original: Smear characteristics#include#cohesive epithelioid cells with moderate cytoplasm and ovoid nuclei
#18756
middle Confidence
Subject:
smear_characteristics
(Morphological characteristics)
→
include
→
Object:
cohesive_epithelioid_cells
(Cell Type)
Original: Smear characteristics#include#cohesive epithelioid cells with moderate cytoplasm and ovoid nuclei
#18753
middle Confidence
Subject:
high-grade_prostatic_intraepithelial_neoplasia
(Histopathological entities)
→
shows
→
Object:
flat_pattern
(Histological morphology)
Original: In 39% of cases/ high-grade PIN#had#a predominantly flat pattern
#18751
middle Confidence
Subject:
HIV_RNA
(Viral RNA)
→
is_detected_by
→
Object:
in_situ_hybridization
(Molecular detection technology)
Original: Epstein-Barr virus early RNA and human immunodeficiency virus RNA#were demonstrated by#in situ hybridization
#18750
middle Confidence
Subject:
Epstein-Barr_virus_early_RNA
(Viral RNA)
→
is_detected_by
→
Object:
in_situ_hybridization
(Molecular detection technology)
Original: Epstein-Barr virus early RNA and human immunodeficiency virus RNA#were demonstrated by#in situ hybridization
#18745
middle Confidence
Subject:
fine-needle_aspirations
(Diagnostic techniques)
→
analyze
→
Object:
nucleoli
(Nucleolus)
Original: fine-needle aspirations#analyze#nucleoli
#18744
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
vimentin
(protein)
Original: tumor cells#are positive for#S-100/ GFAP/ and vimentin
#18743
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
GFAP
(protein)
Original: tumor cells#are positive for#S-100/ GFAP/ and vimentin
#18742
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
S-100
(protein)
Original: tumor cells#are positive for#S-100/ GFAP/ and vimentin
#18732
middle Confidence
Subject:
FH
(Metabolic enzymes)
→
downregulated_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#show#overexpression for 2SC and reduced expression of FH
#18720
middle Confidence
Subject:
diagnosis_of_adenoid_cystic_carcinoma
(Diagnosis conclusion)
→
was_confirmed_by
→
Object:
histopathologic_examination
(Histopathological examination)
Original: diagnosis of adenoid cystic carcinoma#was confirmed#by histopathologic examination
#18712
middle Confidence
Subject:
Hepatoid_carcinoma
(Disease Entity)
→
associated_with
→
Object:
hepatic_differentiation
(Cell differentiation characteristics)
Original: Hepatoid carcinoma#is associated with#hepatic differentiation
#18711
middle Confidence
Subject:
cytologic_evaluation
(Cytological analysis)
→
indicated
→
Object:
malignant_epithelial_tumor
(Tumor phenotype)
Original: cytologic evaluation#indicated#a malignant epithelial tumor with round cells/ prominent nucleoli/ and mitoses
#18710
middle Confidence
Subject:
characteristic_immunophenotypic_features
(Immunophenotypic characteristics)
→
allow
→
Object:
identification_from_unclassified_RCC
(Disease classification)
Original: characteristic morphologic and immunophenotypic features#allow#identification and separation from unclassified RCC
#18709
middle Confidence
Subject:
characteristic_morphologic_features
(Histological characteristics)
→
allow
→
Object:
identification_from_unclassified_RCC
(Disease classification)
Original: characteristic morphologic and immunophenotypic features#allow#identification and separation from unclassified RCC
#18708
middle Confidence
Subject:
follicular_cells
(Follicular cells)
→
must_be_added_to
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Follicular cells#must be added to#the differential diagnosis when Hürthle-like features are seen
#18705
middle Confidence
Subject:
Myoepithelial_carcinoma_of_the_breast
(Tumor type)
→
is
→
Object:
extremely_rare
(Disease phenotype characteristics)
Original: Myoepithelial carcinoma of the breast#is#extremely rare
#18704
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_observed_in
→
Object:
adenocarcinoma_of_apocrine_gland_of_anal_sac
(Anal sac gland adenocarcinoma)
Original: Adenocarcinoma of the apocrine gland of the anal sac#should be included as#a cytologic differential diagnosis when spindle cells and typical epithelial cells are observed
#18703
middle Confidence
Subject:
spindle_cells
(Spindle cells)
→
are_observed_in
→
Object:
adenocarcinoma_of_apocrine_gland_of_anal_sac
(Anal sac gland adenocarcinoma)
Original: Adenocarcinoma of the apocrine gland of the anal sac#should be included as#a cytologic differential diagnosis when spindle cells and typical epithelial cells are observed
#18702
middle Confidence
Subject:
papillary_cystadenocarcinoma_of_salivary_glands
(Papillary cystadenocarcinoma of salivary glands)
→
are
→
Object:
uncommon_lesions_with_low-grade_clinical_features
(Low-grade clinical features)
Original: Papillary cystadenocarcinoma of salivary glands#are#uncommon lesions with low-grade histological and clinical features
#18701
middle Confidence
Subject:
papillary_cystadenocarcinoma_of_salivary_glands
(Papillary cystadenocarcinoma of salivary glands)
→
are
→
Object:
uncommon_lesions_with_low-grade_histological_features
(Low-grade histologic features)
Original: Papillary cystadenocarcinoma of salivary glands#are#uncommon lesions with low-grade histological and clinical features
#18697
middle Confidence
Subject:
urothelial_lesions_with_moderate_cytological_atypia
(Urothelial lesions)
→
exhibit
→
Object:
AgNOR_values_of_well-differentiated_papillary_carcinomas
(AgNOR value (papillary carcinoma control))
Original: Flat urothelial lesions with moderate cytological atypia#exhibit#AgNOR values in the range of well-differentiated papillary carcinomas
#18696
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
display
→
Object:
irregular_nuclear_membranes
(Nuclear membrane abnormalities)
Original: Neoplastic cells#displayed#high-grade nuclear atypia with prominent nucleoli and irregular nuclear membranes
#18695
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
display
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: Neoplastic cells#displayed#high-grade nuclear atypia with prominent nucleoli and irregular nuclear membranes
#18694
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
display
→
Object:
high-grade_nuclear_atypia
(Abnormal nuclear morphology)
Original: Neoplastic cells#displayed#high-grade nuclear atypia with prominent nucleoli and irregular nuclear membranes
#18638
middle Confidence
Subject:
interactive_image_analysis_system
(Digital health tools)
→
is_applied_to
→
Object:
measurement_of_cytological_parameters
(Cell morphology measurements)
Original: Interactive image analysis system#is applied to#measure cytological parameters of adenocarcinoma of the pancreas
#18619
middle Confidence
Subject:
nucleolar_organizer_regions_count
(Molecular markers)
→
differentiations
→
Object:
malignant_mesothelial_cells
(Cell Type)
Original: Morphometry and nucleolar organizer regions count#differentiate#reactive and malignant mesothelial cells in pleural effusions
#18618
middle Confidence
Subject:
nucleolar_organizer_regions_count
(Molecular markers)
→
differentiations
→
Object:
reactive_mesothelial_cells
(Cell Type)
Original: Morphometry and nucleolar organizer regions count#differentiate#reactive and malignant mesothelial cells in pleural effusions
#18617
middle Confidence
Subject:
morphometry
(Morphological analysis)
→
differentiations
→
Object:
malignant_mesothelial_cells
(Cell Type)
Original: Morphometry and nucleolar organizer regions count#differentiate#reactive and malignant mesothelial cells in pleural effusions
#18616
middle Confidence
Subject:
morphometry
(Morphological analysis)
→
differentiations
→
Object:
reactive_mesothelial_cells
(Cell Type)
Original: Morphometry and nucleolar organizer regions count#differentiate#reactive and malignant mesothelial cells in pleural effusions
#18608
middle Confidence
Subject:
AgNOR_score
(Nuclear Organism Markers)
→
correlates_with
→
Object:
clinical_stage
(Clinical staging)
Original: AgNOR score#correlates with#outcome of the disease/ clinical stage/ and OS
#18589
middle Confidence
Subject:
p53
(Tumor suppressor proteins)
→
supplements
→
Object:
diagnosis_of_infiltrative_tumors
(Disease diagnosis)
Original: p53 and vesicular granular adipophilin positivity#supplement#diagnosis of infiltrative tumors
#18569
middle Confidence
Subject:
AgNOR_area
(Molecular detection indicators)
→
is_lower_in
→
Object:
HNPCC
(Tumor tissue)
Original: Higher AgNOR counts and areas#were observed in#sporadic tumors compared to HNPCC
#18568
middle Confidence
Subject:
AgNOR_count
(Molecular detection indicators)
→
is_lower_in
→
Object:
HNPCC
(Tumor tissue)
Original: Higher AgNOR counts and areas#were observed in#sporadic tumors compared to HNPCC
#18567
middle Confidence
Subject:
AgNOR_area
(Molecular detection indicators)
→
is_higher_in
→
Object:
sporadic_tumors
(Tumor tissue)
Original: Higher AgNOR counts and areas#were observed in#sporadic tumors compared to HNPCC
#18566
middle Confidence
Subject:
AgNOR_count
(Molecular detection indicators)
→
is_higher_in
→
Object:
sporadic_tumors
(Tumor tissue)
Original: Higher AgNOR counts and areas#were observed in#sporadic tumors compared to HNPCC
#18557
middle Confidence
Subject:
mean_AgNOR_count
(Molecular pathology indicators)
→
is_higher_in
→
Object:
abnormal_interphase_cells
(Cell phenotype)
Original: Mean AgNOR count#is higher in#abnormal interphase cells than in normal interphase cells
#18555
middle Confidence
Subject:
RCA-1_receptor_expression
(RCA-1 receptor expression)
→
is_heterogeneous_in
→
Object:
high-grade_gliomas
(Glioma)
Original: combined RCA-1 histochemical and Ag-NOR silver colloid staining#reveals#heterogeneous expression of RCA-1 receptor in high-grade gliomas
#18548
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region-associated protein)
→
is_useful_in
→
Object:
evaluation_of_neoplastic_and_preneoplastic_colon_lesions
(Evaluation of colon tumors and precancerous lesions)
Original: AgNOR counts#are useful in#the evaluation of neoplastic and preneoplastic lesions of the colon
#18547
middle Confidence
Subject:
AgNOR_protein
(Nucleolar organizer region-associated protein)
→
is_elevated_in
→
Object:
malignant_cells
(Malignant cells)
Original: AgNOR protein expression#is elevated in#malignant cells compared to normal cells
#18541
middle Confidence
Subject:
Ki67_immunoreactivity
(Ki67 immunoreactivity)
→
measured_in
→
Object:
vertical_growth_phase_melanoma
(Vertical growth phase melanoma)
Original: AgNOR staining and Ki-67 immunoreactivity#were determined in#ordinary nevi/ dysplastic nevi/ radial growth phase melanomas/ and vertical growth phase melanomas
#18540
middle Confidence
Subject:
Ki67_immunoreactivity
(Ki67 immunoreactivity)
→
measured_in
→
Object:
radial_growth_phase_melanoma
(Radial growth phase melanoma)
Original: AgNOR staining and Ki-67 immunoreactivity#were determined in#ordinary nevi/ dysplastic nevi/ radial growth phase melanomas/ and vertical growth phase melanomas
#18539
middle Confidence
Subject:
Ki67_immunoreactivity
(Ki67 immunoreactivity)
→
measured_in
→
Object:
dysplastic_nevi
(Atypical mole)
Original: AgNOR staining and Ki-67 immunoreactivity#were determined in#ordinary nevi/ dysplastic nevi/ radial growth phase melanomas/ and vertical growth phase melanomas
#18538
middle Confidence
Subject:
Ki67_immunoreactivity
(Ki67 immunoreactivity)
→
measured_in
→
Object:
ordinary_nevi
(Common mole)
Original: AgNOR staining and Ki-67 immunoreactivity#were determined in#ordinary nevi/ dysplastic nevi/ radial growth phase melanomas/ and vertical growth phase melanomas
#18537
middle Confidence
Subject:
AgNOR_staining
(Nucleolar organizer region staining)
→
measured_in
→
Object:
vertical_growth_phase_melanoma
(Vertical growth phase melanoma)
Original: AgNOR staining and Ki-67 immunoreactivity#were determined in#ordinary nevi/ dysplastic nevi/ radial growth phase melanomas/ and vertical growth phase melanomas
#18536
middle Confidence
Subject:
AgNOR_staining
(Nucleolar organizer region staining)
→
measured_in
→
Object:
radial_growth_phase_melanoma
(Radial growth phase melanoma)
Original: AgNOR staining and Ki-67 immunoreactivity#were determined in#ordinary nevi/ dysplastic nevi/ radial growth phase melanomas/ and vertical growth phase melanomas
#18535
middle Confidence
Subject:
AgNOR_staining
(Nucleolar organizer region staining)
→
measured_in
→
Object:
dysplastic_nevi
(Atypical mole)
Original: AgNOR staining and Ki-67 immunoreactivity#were determined in#ordinary nevi/ dysplastic nevi/ radial growth phase melanomas/ and vertical growth phase melanomas
#18534
middle Confidence
Subject:
AgNOR_staining
(Nucleolar organizer region staining)
→
measured_in
→
Object:
ordinary_nevi
(Common mole)
Original: AgNOR staining and Ki-67 immunoreactivity#were determined in#ordinary nevi/ dysplastic nevi/ radial growth phase melanomas/ and vertical growth phase melanomas
#18515
middle Confidence
Subject:
nuclear_image_histometry_combined_with_morphometric_analysis_of_AgNORs
(Analytical methods)
→
enabled
→
Object:
discrimination_of_nonmetastatic_tumors
(Diagnosis)
Original: nuclear image histometry in combination with morphometric analysis of AgNORs#enabled#discrimination between metastatic and nonmetastatic tumors
#18514
middle Confidence
Subject:
nuclear_image_histometry_combined_with_morphometric_analysis_of_AgNORs
(Analytical methods)
→
enabled
→
Object:
discrimination_of_metastatic_tumors
(Diagnosis)
Original: nuclear image histometry in combination with morphometric analysis of AgNORs#enabled#discrimination between metastatic and nonmetastatic tumors
#18487
middle Confidence
Subject:
High-grade_squamous_intraepithelial_lesion
(Pathological entity)
→
found_in
→
Object:
SMILE_case
(Disease phenotype)
Original: High-grade squamous intraepithelial lesion#was found in#77% of SMILE cases
#18485
middle Confidence
Subject:
proliferating_cells
(Proliferating cells)
→
were_positive_for
→
Object:
CD207
(Protein markers)
Original: proliferating cells#were positive for#S100/ CD1a/ and CD207 (langerin)
#18484
middle Confidence
Subject:
proliferating_cells
(Proliferating cells)
→
were_positive_for
→
Object:
CD1A
(Protein markers)
Original: proliferating cells#were positive for#S100/ CD1a/ and CD207 (langerin)
#18483
middle Confidence
Subject:
proliferating_cells
(Proliferating cells)
→
were_positive_for
→
Object:
S100
(Protein markers)
Original: proliferating cells#were positive for#S100/ CD1a/ and CD207 (langerin)
#18480
middle Confidence
Subject:
Fine_needle_aspiration
(Diagnostic techniques)
→
showed
→
Object:
highly_cellular_smear_with_dispersed_single_cells_and_clusters
(Cytological manifestations)
Original: Fine needle aspiration#showed#a highly cellular smear with dispersed single cells and clusters
#18451
middle Confidence
Subject:
TFE3_gene_rearrangement
(Gene rearrangement)
→
is_present_in
→
Object:
tumor
(Tumor tissue)
Original: TFE3 gene rearrangement#was present in#all four tumors
#18447
middle Confidence
Subject:
Histopathology
(Diagnostic Methods)
→
shows
→
Object:
sheets_of_monotonously_small_to_medium_sized_neoplastic_cells
(Cell morphological characteristics)
Original: Histopathology#showed#sheets of monotonously small-to-medium-sized neoplastic cells with uniform round-to-oval nuclei and inconspicuous nucleoli
#18446
middle Confidence
Subject:
Cytologic_examination
(Diagnostic Methods)
→
shows
→
Object:
glandlike_clusters_of_large_cells_with_granular_cytoplasm_and_prominent_nucleoli
(Cell morphological characteristics)
Original: Cytologic examination#showed#glandlike clusters of large cells with granular cytoplasm and prominent nucleoli
#18442
middle Confidence
Subject:
cytologic_results
(Cytology results)
→
are_consistent_with
→
Object:
carcinoma
(Tumor phenotype)
Original: Cytologic results#were consistent with#epithelial neoplasia/ likely carcinoma
#18441
middle Confidence
Subject:
cytologic_results
(Cytology results)
→
are_consistent_with
→
Object:
epithelial_neoplasia
(Tumor phenotype)
Original: Cytologic results#were consistent with#epithelial neoplasia/ likely carcinoma
#18433
middle Confidence
Subject:
ALK
(Tyrosine kinase)
→
is_positive_in
→
Object:
entity_with_aggressive_clinical_course
(Tumor Entities)
Original: This entity#has#distinctive clinicopathologic features: aggressive clinical course/ craniofacial bone preference/ spindle and epithelioid histomorphology/ positive immunohistochemistry for epithelial markers/ ALK/ and myogenic markers
#18432
middle Confidence
Subject:
tumor_structure
(Tumor structure)
→
is_typical_of
→
Object:
extraskeletal_myxoid_chondrosarcoma
(Tumor)
Original: tumor structure#is typical of#extraskeletal myxoid chondrosarcoma
#18431
middle Confidence
Subject:
chordoid_glioma
(Tumor)
→
is_described_on
→
Object:
crush_cytology
(Diagnostic techniques)
Original: chordoid glioma#is described on#crush cytology
#18430
middle Confidence
Subject:
rhabdoid_areas
(Histological morphology)
→
represent
→
Object:
phenotypic_variant_of_gastric_adenocarcinoma
(Disease phenotype)
Original: rhabdoid areas#represent#a phenotypic variant of gastric adenocarcinoma
#18429
middle Confidence
Subject:
metastases_of_extramammary_tumors
(Tumor metastasis)
→
occur_in
→
Object:
breast
(organ)
Original: Metastases of tumors of extramammary origin#to the breast#are extremely uncommon
#18420
middle Confidence
Subject:
Large_epithelioid_cells
(Cell Type)
→
are_surrounded_by
→
Object:
Fibrovascular_stroma
(Organizational Structure)
Original: Tumors#consist of#nests of large epithelioid cells surrounded by fibrovascular stroma
#18419
middle Confidence
Subject:
Nests
(Organizational Structure)
→
contain
→
Object:
Large_epithelioid_cells
(Cell Type)
Original: Tumors#consist of#nests of large epithelioid cells surrounded by fibrovascular stroma
#18418
middle Confidence
Subject:
Tumors
(Tumor tissue)
→
consist_of
→
Object:
Nests
(Organizational Structure)
Original: Tumors#consist of#nests of large epithelioid cells surrounded by fibrovascular stroma
#18404
middle Confidence
Subject:
Immunostaining
(Histological detection technology)
→
may_resolve
→
Object:
atypical small acinar proliferation diagnoses
(Tumor diagnosis events)
Original: Immunostaining#may resolve#atypical small acinar proliferation diagnoses using cytoplasmic keratin 34betaE12 or nuclear p63
#18403
middle Confidence
Subject:
high-grade prostatic intraepithelial neoplasia
(Preneoplastic lesions)
→
predictions
→
Object:
cancer on repeat biopsy
(Tumor diagnosis events)
Original: Isolated high-grade prostatic intraepithelial neoplasia#predicts#cancer on repeat biopsy in 23% of cases
#18380
middle Confidence
Subject:
Frameshift_mutation
(Gene mutation)
→
caused
→
Object:
loss_of_FH_staining
(Molecular markers)
Original: Frameshift mutation#caused#loss of FH staining
#18370
middle Confidence
Subject:
alveolar_structures
(Organizational Structure)
→
surrounded_by
→
Object:
delicate_blood_sinuses
(Microvascular)
Original: tumor cells#had#clear or eosinophilic cytoplasm and prominent nucleoli/ arranged in alveolar structures surrounded by delicate blood sinuses
#18369
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
arranged_in
→
Object:
alveolar_structures
(Organizational Structure)
Original: tumor cells#had#clear or eosinophilic cytoplasm and prominent nucleoli/ arranged in alveolar structures surrounded by delicate blood sinuses
#18362
middle Confidence
Subject:
computed_tomography_scans
(Medical Imaging)
→
show
→
Object:
mass_with_smooth_border
(Image characteristics)
Original: computed tomography scans#show#a mass with a smooth border invading the thoracic wall
#18360
middle Confidence
Subject:
epithelioid_cells
(Cell Type)
→
shows
→
Object:
large_nucleoli
(Nuclear characteristics)
Original: epithelioid cells#show#pronounced nuclear pleomorphism and atypia with central large nucleoli
#18359
middle Confidence
Subject:
epithelioid_cells
(Cell Type)
→
shows
→
Object:
cellular_atypia
(Cell morphology)
Original: epithelioid cells#show#pronounced nuclear pleomorphism and atypia with central large nucleoli
#18358
middle Confidence
Subject:
epithelioid_cells
(Cell Type)
→
shows
→
Object:
nuclear_pleomorphism
(Cell morphology)
Original: epithelioid cells#show#pronounced nuclear pleomorphism and atypia with central large nucleoli
#18356
middle Confidence
Subject:
morphologic_criteria
(Morphological criteria)
→
classifies
→
Object:
atypical_form_of_Ewing_sarcoma
(Disease phenotype)
Original: Morphologic criteria#classify#typical and atypical forms of ES
#18355
middle Confidence
Subject:
morphologic_criteria
(Morphological criteria)
→
classifies
→
Object:
typical_form_of_Ewing_sarcoma
(Disease phenotype)
Original: Morphologic criteria#classify#typical and atypical forms of ES
#18354
middle Confidence
Subject:
Brushings_and_washings
(Cytoscopy and flushing specimens)
→
achieved
→
Object:
accuracy_in_diagnosing_bronchogenic_carcinoma
(Diagnostic Accuracy)
Original: Brushings and washings during fiberoptic bronchoscopy#achieved#76% accuracy in diagnosing bronchogenic carcinoma
#18351
middle Confidence
Subject:
abnormal_cells
(Cell phenotype)
→
positive_for
→
Object:
glial_fibrillary_acidic_protein
(Structural proteins)
Original: Abnormal cells#are positive for#glial fibrillary acidic protein (GFAP)/ Nissl/ and Holzer's stains
#18347
middle Confidence
Subject:
histologic_changes_in_VIN1
(Pathological changes)
→
are_described_as
→
Object:
HPV_effect
(Virus infection characteristics)
Original: Histologic changes in VIN 1#are described as#flat condyloma or HPV effect
#18346
middle Confidence
Subject:
histologic_changes_in_VIN1
(Pathological changes)
→
are_described_as
→
Object:
flat_condyloma
(Pathological characteristics)
Original: Histologic changes in VIN 1#are described as#flat condyloma or HPV effect
#18338
middle Confidence
Subject:
diagnosis_of_adenosis
(Disease diagnosis)
→
is_confirmed_with
→
Object:
antibodies_to_high-molecular-weight_cytokeratin
(Antibody markers)
Original: diagnosis of adenosis#is confirmed with#antibodies to high-molecular-weight cytokeratin
#18337
middle Confidence
Subject:
villoglandular_adenocarcinoma
(Adenocarcinoma)
→
is_observed_in
→
Object:
uterine_cervix
(Organ tissue)
Original: villoglandular adenocarcinoma#is observed in#uterine cervix
#18334
middle Confidence
Subject:
Melanotic_Xp11_renal_cell_carcinoma
(Tumor diseases)
→
is_associated_with
→
Object:
SFPQ-TFE3_gene_fusion
(Gene fusion events)
Original: Melanotic Xp11 renal cell carcinoma#is associated with#SFPQ-TFE3 gene fusion
#18323
middle Confidence
Subject:
positive_transrectal_ultrasound
(Imaging tests)
→
predictions
→
Object:
carcinoma
(Tumor diseases)
Original: Positive transrectal ultrasound#predicted#carcinoma on follow-up
#18322
middle Confidence
Subject:
positive_DRE
(Clinical examination)
→
predictions
→
Object:
carcinoma
(Tumor diseases)
Original: Positive DRE#predicted#carcinoma on follow-up
#18321
middle Confidence
Subject:
repeat_biopsy
(Pathological operation)
→
diagnosed
→
Object:
cancer
(Tumor diseases)
Original: Repeat biopsy#diagnosed#cancer in 10 of 22 men
#18314
middle Confidence
Subject:
brain_lesion_biopsy_specimen
(Tissue samples)
→
showed
→
Object:
proliferation_of_large_lymphoid_cells_in_small_vessels
(Cellular Processes)
Original: biopsy specimens from brain lesion#showed#proliferation of large lymphoid cells filling lumina of small vessels
#18313
middle Confidence
Subject:
EUS_and_imaging_findings
(Imaging findings)
→
were_suspicious_for
→
Object:
invasion
(Disease phenotype)
Original: EUS and imaging findings#were suspicious for#invasion
#18312
middle Confidence
Subject:
FNAB
(Diagnostic techniques)
→
is_used_as
→
Object:
diagnostic_modality_for_Ewing's_sarcoma
(Diagnostic Methods)
Original: FNAB#is used as#diagnostic modality for Ewing's sarcoma
#18303
middle Confidence
Subject:
glandular_cells
(Cell Type)
→
present_in
→
Object:
endocervical_adenocarcinoma
(Tumor type)
Original: Numerous glandular cells#were present in#51 cases
#18284
middle Confidence
Subject:
Clear_cell_adenocarcinoma
(Tumor diseases)
→
shows
→
Object:
clear_cytoplasm
(Cell morphology)
Original: Clear cell adenocarcinomas#showed#marked nuclear pleomorphism/ prominent nucleoli/ clear cytoplasm/ and necrosis
#18283
middle Confidence
Subject:
Clear_cell_adenocarcinoma
(Tumor diseases)
→
shows
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Clear cell adenocarcinomas#showed#marked nuclear pleomorphism/ prominent nucleoli/ clear cytoplasm/ and necrosis
#18282
middle Confidence
Subject:
Clear_cell_adenocarcinoma
(Tumor diseases)
→
shows
→
Object:
nuclear_pleomorphism
(Cell morphology)
Original: Clear cell adenocarcinomas#showed#marked nuclear pleomorphism/ prominent nucleoli/ clear cytoplasm/ and necrosis
#18270
middle Confidence
Subject:
Immunohistochemistry
(Molecular detection technology)
→
helps_in_excluding
→
Object:
morphologic_mimics
(Morphological artifacts)
Original: Immunohistochemistry#helps in excluding#morphologic mimics
#18269
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
produces
→
Object:
Thyroglobulin
(protein)
Original: Immunochemical findings#confirmed#thyroglobulin production by neoplastic cells
#18262
middle Confidence
Subject:
Tumor_cells
(cancer cell)
→
weakly_expresses
→
Object:
CD56
(Cell adhesion molecules)
Original: Tumor cells#weakly expressed#synaptophysin and CD56
#18261
middle Confidence
Subject:
Tumor_cells
(cancer cell)
→
weakly_expresses
→
Object:
synaptophysin
(Neuroendocrine markers)
Original: Tumor cells#weakly expressed#synaptophysin and CD56
#18259
middle Confidence
Subject:
cytologic_studies
(Cytology)
→
are_evaluated_for
→
Object:
diagnostic_significance_in_pancreatic_tumors
(Diagnostic significance)
Original: Cytologic studies#are evaluated for#diagnostic significance in pancreatic tumors
#18258
middle Confidence
Subject:
metastasis_from_malignant_ameloblastoma
(Disease process)
→
is_described_with
→
Object:
histological_confirmation
(Diagnostic techniques)
Original: metastasis from malignant ameloblastoma#is described with#histological confirmation
#18252
middle Confidence
Subject:
tumors
(Tumor)
→
to_be_distinguished_from
→
Object:
lobular_carcinoma
(Malignant tumors)
Original: tumors#to be distinguished from#glassy cell carcinoma/ large cell/ non-keratinizing squamous cell carcinoma/ and lobular type carcinoma
#18251
middle Confidence
Subject:
tumors
(Tumor)
→
to_be_distinguished_from
→
Object:
squamous_cell_carcinoma
(Malignant tumors)
Original: tumors#to be distinguished from#glassy cell carcinoma/ large cell/ non-keratinizing squamous cell carcinoma/ and lobular type carcinoma
#18250
middle Confidence
Subject:
tumors
(Tumor)
→
to_be_distinguished_from
→
Object:
large_cell_carcinoma
(Malignant tumors)
Original: tumors#to be distinguished from#glassy cell carcinoma/ large cell/ non-keratinizing squamous cell carcinoma/ and lobular type carcinoma
#18249
middle Confidence
Subject:
tumors
(Tumor)
→
to_be_distinguished_from
→
Object:
glassy_cell_carcinoma
(Malignant tumors)
Original: tumors#to be distinguished from#glassy cell carcinoma/ large cell/ non-keratinizing squamous cell carcinoma/ and lobular type carcinoma
#18248
middle Confidence
Subject:
enlarged_nuclei_and_nucleoli
(Cell morphology)
→
are_characteristic_for
→
Object:
Spitzoid_melanoma
(Malignant tumors)
Original: Spitzoid melanomas#are distinguished from#Spitz nevi and atypical Spitz tumors by enlarged nuclei and nucleoli
#18247
middle Confidence
Subject:
Spitzoid_melanoma
(Malignant tumors)
→
are_distinguished_from
→
Object:
atypical_Spitz_tumor
(Tumor phenotype)
Original: Spitzoid melanomas#are distinguished from#Spitz nevi and atypical Spitz tumors by enlarged nuclei and nucleoli
#18246
middle Confidence
Subject:
Spitzoid_melanoma
(Malignant tumors)
→
are_distinguished_from
→
Object:
Spitz_nevus
(Benign tumors)
Original: Spitzoid melanomas#are distinguished from#Spitz nevi and atypical Spitz tumors by enlarged nuclei and nucleoli
#18245
middle Confidence
Subject:
cytologic_features_of_SMCC_cells
(Cell morphology)
→
are_characteristic_for
→
Object:
specific_diagnosis_of_SMCC
(Disease diagnosis)
Original: cytologic features of SMCC cells#are characteristic for#specific diagnosis
#18244
middle Confidence
Subject:
Cytologic_features
(Cytological characteristics)
→
may_be_helpful_in
→
Object:
diagnosis_of_MPNSTs
(Diagnosis of Malignant Peripheral Nerve Sheath Tumor)
Original: Cytologic features#may be helpful in#diagnosis of MPNSTs
#18242
middle Confidence
Subject:
rhabdoid_renal_tumor
(Tumor)
→
shows
→
Object:
large_nucleoli
(Cell structure characteristics)
Original: Conspicuous filamentous cytoplasmic inclusions or large nucleoli#were#typical findings in rhabdoid renal tumors
#18241
middle Confidence
Subject:
rhabdoid_renal_tumor
(Tumor)
→
shows
→
Object:
filamentous_cytoplasmic_inclusions
(Cell structure characteristics)
Original: Conspicuous filamentous cytoplasmic inclusions or large nucleoli#were#typical findings in rhabdoid renal tumors
#18239
middle Confidence
Subject:
osteocementum-like_tissue
(Tumor tissue morphology)
→
is_rimmed_by
→
Object:
polygonal_or_plump_tumor_cells
(Tumor cells)
Original: Lesion#consisted of#osteocementum-like tissue rimmed with polygonal or plump tumor cells
#18238
middle Confidence
Subject:
Lesion
(Tumor tissue)
→
consists_of
→
Object:
osteocementum-like_tissue
(Tumor tissue morphology)
Original: Lesion#consisted of#osteocementum-like tissue rimmed with polygonal or plump tumor cells
#18233
middle Confidence
Subject:
characteristics
(Disease phenotype characteristics)
→
correspond_to
→
Object:
Burkitt's_Lymphoma
(disease)
Original: characteristics#correspond to#human Burkitt's Lymphoma
#18230
middle Confidence
Subject:
osteonectin
(Extracellular matrix proteins)
→
shows_positivity_in
→
Object:
Tumor cells
(Tumor cells)
Original: Tumor cells#revealed positivity for#vimentin and osteonectin
#18229
middle Confidence
Subject:
vimentin
(Cytoskeletal proteins)
→
shows_positivity_in
→
Object:
Tumor cells
(Tumor cells)
Original: Tumor cells#revealed positivity for#vimentin and osteonectin
#18200
middle Confidence
Subject:
Tumor
(Tumor)
→
expresses
→
Object:
S-100
(S-100 protein)
Original: Tumor#expresses#EMA/ ER/ c-erbB-2/ p53/ and S-100
#18197
middle Confidence
Subject:
Tumor
(Tumor)
→
expresses
→
Object:
ER
(Estrogen receptor)
Original: Tumor#expresses#EMA/ ER/ c-erbB-2/ p53/ and S-100
#18196
middle Confidence
Subject:
Tumor
(Tumor)
→
expresses
→
Object:
EMA
(Epithelial membrane antigen)
Original: Tumor#expresses#EMA/ ER/ c-erbB-2/ p53/ and S-100
#18195
middle Confidence
Subject:
Soluble_adenylyl_cyclase
(Adenylate cyclase)
→
is_expressed_in
→
Object:
acral_melanomas
(Tumor type)
Original: Soluble adenylyl cyclase#is expressed in#acral melanomas
#18194
middle Confidence
Subject:
Nonepitheliotropic_lymphoma
(Tumor type)
→
is_characterized_by
→
Object:
extensive_dermal_necrosis
(Tissue necrosis phenotype)
Original: Nonepitheliotropic lymphoma#is characterized by#unusual tumor cells with irregularly shaped nuclei and extensive dermal necrosis
#18193
middle Confidence
Subject:
Nonepitheliotropic_lymphoma
(Tumor type)
→
is_characterized_by
→
Object:
tumor_cells_with_irregular_nuclei
(Abnormal tumor cell phenotype)
Original: Nonepitheliotropic lymphoma#is characterized by#unusual tumor cells with irregularly shaped nuclei and extensive dermal necrosis
#18188
middle Confidence
Subject:
tumor
(Tumor)
→
was_diagnosed_as
→
Object:
sacrococcygeal_mature_teratoma_with_malignant_steroidogenic_transformation
(Type of diagnosis)
Original: tumor#was diagnosed as#sacrococcygeal mature teratoma with malignant steroidogenic transformation
#18186
middle Confidence
Subject:
ulcerative_colitis_case
(Case)
→
shows
→
Object:
regenerative_reparative_features
(Histopathological characteristics)
Original: ulcerative colitis case#showed#widespread ulcers and regenerative/reparative features
#18185
middle Confidence
Subject:
ulcerative_colitis_case
(Case)
→
shows
→
Object:
widespread_ulcers
(Histopathological characteristics)
Original: ulcerative colitis case#showed#widespread ulcers and regenerative/reparative features
#18173
middle Confidence
Subject:
Abnormal_phenotype
(Cell phenotype)
→
is_consistent_with
→
Object:
plasma_cell_tumor
(Tumor)
Original: Monoclonal plasma cell#had#abnormal phenotype consistent with plasma cell tumor
#18170
middle Confidence
Subject:
primary_cutaneous_B-cell_lymphoma
(Tumor type)
→
manifests_as
→
Object:
erythematous_indurated_nodules
(Clinical phenotype)
Original: A female patient 85 years of age#manifested#primary cutaneous B-cell lymphoma with multiple firm erythematous indurated nodules
#18161
middle Confidence
Subject:
AIDS-related_primary_CNS_lymphoma_tumor
(Tumor tissue)
→
were_evaluated_for
→
Object:
EBV_presence
(Virus Detection)
Original: Tumors from AIDS-related primary CNS lymphoma patients#were evaluated for#EBV presence
#18160
middle Confidence
Subject:
Blastic_plasmacytoid_dendritic_cell_neoplasm
(disease)
→
is_associated_with
→
Object:
cytopathologic_findings
(Cytological characteristics)
Original: Blastic plasmacytoid dendritic cell neoplasm#is associated with#cytopathologic findings
#18159
middle Confidence
Subject:
immunohistochemical_findings
(Immunohistochemical characteristics)
→
suggested
→
Object:
pseudomyogenic_hemangioendothelioma
(disease)
Original: Pathological and immunohistochemical findings#suggested#pseudomyogenic hemangioendothelioma (PHE)
#18158
middle Confidence
Subject:
pathological_findings
(Pathological characteristics)
→
suggested
→
Object:
pseudomyogenic_hemangioendothelioma
(disease)
Original: Pathological and immunohistochemical findings#suggested#pseudomyogenic hemangioendothelioma (PHE)
#18156
middle Confidence
Subject:
imprint_cytology_findings
(Cytological morphological characteristics)
→
classified_into
→
Object:
YST_cytology_pattern
(Cytological subtype)
Original: Imprint cytology findings of YST#were classified into#4 patterns
#18134
middle Confidence
Subject:
tumor_cells
(Cell Type)
→
expressed
→
Object:
alkaline_phosphatase
(Enzymes)
Original: tumor cells#expressed#vimentin/ osteopontin/ vascular endothelial growth factor/ CD10/ and alkaline phosphatase
#18133
middle Confidence
Subject:
tumor_cells
(Cell Type)
→
expressed
→
Object:
CD10
(Cell surface molecules)
Original: tumor cells#expressed#vimentin/ osteopontin/ vascular endothelial growth factor/ CD10/ and alkaline phosphatase
#18132
middle Confidence
Subject:
tumor_cells
(Cell Type)
→
expressed
→
Object:
VEGFA
(Angiogenic Factors)
Original: tumor cells#expressed#vimentin/ osteopontin/ vascular endothelial growth factor/ CD10/ and alkaline phosphatase
#18131
middle Confidence
Subject:
tumor_cells
(Cell Type)
→
expressed
→
Object:
osteopontin
(Extracellular matrix proteins)
Original: tumor cells#expressed#vimentin/ osteopontin/ vascular endothelial growth factor/ CD10/ and alkaline phosphatase
#18130
middle Confidence
Subject:
tumor_cells
(Cell Type)
→
expressed
→
Object:
vimentin
(Intermediate filament protein)
Original: tumor cells#expressed#vimentin/ osteopontin/ vascular endothelial growth factor/ CD10/ and alkaline phosphatase
#18129
middle Confidence
Subject:
spindle_shaped_cells
(Cell Type)
→
expressed
→
Object:
vimentin
(Intermediate filament protein)
Original: spindle shaped cells#expressed#GFAP and vimentin
#18128
middle Confidence
Subject:
spindle_shaped_cells
(Cell Type)
→
expressed
→
Object:
GFAP
(glial fibrillary acid protein)
Original: spindle shaped cells#expressed#GFAP and vimentin
#18127
middle Confidence
Subject:
perivascular_epithelioid_tumors
(Tumor)
→
demonstrate
→
Object:
melanocytic_immunomarkers
(Molecular markers)
Original: Perivascular epithelioid tumors (PEComa)#demonstrate#positivity for muscular and melanocytic immuno-markers
#18126
middle Confidence
Subject:
perivascular_epithelioid_tumors
(Tumor)
→
demonstrate
→
Object:
muscular_immunomarkers
(Molecular markers)
Original: Perivascular epithelioid tumors (PEComa)#demonstrate#positivity for muscular and melanocytic immuno-markers
#18122
middle Confidence
Subject:
oncocytic_carcinoma
(Tumor diseases)
→
is_found_as
→
Object:
lymphadenectasis
(Swollen lymph nodes)
Original: Oncocytic carcinoma#is found as#painless/ irregular-shaped mass or lymphadenectasis in head and neck
#18121
middle Confidence
Subject:
oncocytic_carcinoma
(Tumor diseases)
→
is_found_as
→
Object:
painless_irregular_shaped_mass
(Painless irregular lump)
Original: Oncocytic carcinoma#is found as#painless/ irregular-shaped mass or lymphadenectasis in head and neck
#18116
middle Confidence
Subject:
oncocytic_carcinoma_of_salivary_gland
(Tumor diseases)
→
is_studied_for
→
Object:
diagnosis
(diagnosis)
Original: Oncocytic carcinoma of salivary gland#is studied for#clinicopathological features/ diagnosis/ treatment/ and prognosis
#18114
middle Confidence
Subject:
large_cell_clusters
(Cell clusters)
→
improves
→
Object:
diagnostic_specificity_for_squamous_cell_carcinoma
(Diagnostic specificity)
Original: Presence of necrosis >10% and large cell clusters#improves#diagnostic sensitivity and specificity for squamous cell carcinoma
#18113
middle Confidence
Subject:
presence_of_necrosis_>10%
(Necrosis > 10%)
→
improves
→
Object:
diagnostic_sensitivity_for_squamous_cell_carcinoma
(Diagnostic sensitivity)
Original: Presence of necrosis >10% and large cell clusters#improves#diagnostic sensitivity and specificity for squamous cell carcinoma
#18080
middle Confidence
Subject:
keratin_labeling_of_filaments
(Protein expression)
→
correlates_with
→
Object:
immunohistochemical_staining_at_light-microscopic_level
(Immunohistochemistry)
Original: Positive keratin labeling of filaments arranged in paranuclear aggregates#correlates with#immunohistochemical staining at the light-microscopic level
#18079
middle Confidence
Subject:
RCC
(Tumor type)
→
shows_positive_expression_of
→
Object:
MAK-6
(Cytokeratin)
Original: Both TCC and RCC#were positive for#EMA and cytokeratins CAM-5.2/ AE1/AE3/ MAK-6
#18078
middle Confidence
Subject:
RCC
(Tumor type)
→
shows_positive_expression_of
→
Object:
AE1/AE3
(Cytokeratin)
Original: Both TCC and RCC#were positive for#EMA and cytokeratins CAM-5.2/ AE1/AE3/ MAK-6
#18077
middle Confidence
Subject:
RCC
(Tumor type)
→
shows_positive_expression_of
→
Object:
CAM-5.2
(Cytokeratin)
Original: Both TCC and RCC#were positive for#EMA and cytokeratins CAM-5.2/ AE1/AE3/ MAK-6
#18076
middle Confidence
Subject:
RCC
(Tumor type)
→
shows_positive_expression_of
→
Object:
EMA
(epithelial cell differentiation antigen)
Original: Both TCC and RCC#were positive for#EMA and cytokeratins CAM-5.2/ AE1/AE3/ MAK-6
#18075
middle Confidence
Subject:
TCC
(Tumor type)
→
shows_positive_expression_of
→
Object:
MAK-6
(Cytokeratin)
Original: Both TCC and RCC#were positive for#EMA and cytokeratins CAM-5.2/ AE1/AE3/ MAK-6
#18074
middle Confidence
Subject:
TCC
(Tumor type)
→
shows_positive_expression_of
→
Object:
AE1/AE3
(Cytokeratin)
Original: Both TCC and RCC#were positive for#EMA and cytokeratins CAM-5.2/ AE1/AE3/ MAK-6
#18073
middle Confidence
Subject:
TCC
(Tumor type)
→
shows_positive_expression_of
→
Object:
CAM-5.2
(Cytokeratin)
Original: Both TCC and RCC#were positive for#EMA and cytokeratins CAM-5.2/ AE1/AE3/ MAK-6
#18072
middle Confidence
Subject:
TCC
(Tumor type)
→
shows_positive_expression_of
→
Object:
EMA
(epithelial cell differentiation antigen)
Original: Both TCC and RCC#were positive for#EMA and cytokeratins CAM-5.2/ AE1/AE3/ MAK-6
#18066
middle Confidence
Subject:
sharply_angulated_nuclear_rims
(Nuclear morphology)
→
included_in
→
Object:
criteria_for_malignancy
(Diagnostic criteria)
Original: Criteria for malignancy#included#sharply angulated nuclear rims
#18062
middle Confidence
Subject:
patient
(Patient characteristics)
→
diagnosed_with
→
Object:
rare_peripheral_leukemic_presentation
(Disease phenotype)
Original: Patient#was diagnosed with#ALCL with a rare peripheral leukemic presentation
#18061
middle Confidence
Subject:
AML_with_erythroid_differentiation
(Tumor subtype)
→
highlights
→
Object:
need_for_immunohistochemical_profiles
(Immunohistochemistry analysis requirements)
Original: AMLs with erythroid differentiation#highlight#the need for differential diagnosis and immunohistochemical profiles
#18060
middle Confidence
Subject:
AML_with_erythroid_differentiation
(Tumor subtype)
→
highlights
→
Object:
need_for_differential_diagnosis
(Clinical diagnostic needs)
Original: AMLs with erythroid differentiation#highlight#the need for differential diagnosis and immunohistochemical profiles
#18059
middle Confidence
Subject:
Hematopoietic neoplasm
(Tumor type)
→
is_involved_in
→
Object:
pleural_effusion_cases
(Clinical Cases)
Original: Hematopoietic neoplasm#is involved in#a minority of pleural effusion cases
#18010
middle Confidence
Subject:
42-year-old_woman
(Patient characteristics)
→
presented_with
→
Object:
rhinorrhea
(Clinical symptoms)
Original: A 42-year-old woman#presented with#nasal obstruction and rhinorrhea
#18009
middle Confidence
Subject:
42-year-old_woman
(Patient characteristics)
→
presented_with
→
Object:
nasal_obstruction
(Clinical symptoms)
Original: A 42-year-old woman#presented with#nasal obstruction and rhinorrhea
#18002
middle Confidence
Subject:
fibrolamellar_carcinoma
(Fibrolamellar carcinoma of the liver)
→
is_characterized_by
→
Object:
large_polygonal_cells
(Tumor cell morphology)
Original: fibrolamellar carcinoma#is characterized by#large polygonal cells with oncocytic cytoplasm and prominent nucleoli
#17992
middle Confidence
Subject:
cytologic_findings
(Cytological manifestations)
→
were_retrospectively_examined_in
→
Object:
well-differentiated_villoglandular_adenocarcinoma
(Tumor type)
Original: Cytologic findings#were retrospectively examined in#well-differentiated villoglandular adenocarcinoma
#17959
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
stain_positively_for
→
Object:
EMA
(Epithelial membrane antigen)
Original: neoplastic cells#stain positively for#MUM1/ CD138/ CD45/ and EMA
#17958
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
stain_positively_for
→
Object:
CD45
(Membrane Protein)
Original: neoplastic cells#stain positively for#MUM1/ CD138/ CD45/ and EMA
#17957
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
stain_positively_for
→
Object:
CD138
(Membrane Protein)
Original: neoplastic cells#stain positively for#MUM1/ CD138/ CD45/ and EMA
#17956
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
stain_positively_for
→
Object:
MUM1
(protein)
Original: neoplastic cells#stain positively for#MUM1/ CD138/ CD45/ and EMA
#17955
middle Confidence
Subject:
nuclear_atypia
(Nuclear abnormalities)
→
is_associated_with
→
Object:
mucinous_adenocarcinoma
(Adenocarcinoma)
Original: nuclear atypia#is associated with#mucinous adenocarcinoma
#17954
middle Confidence
Subject:
cells
(cell)
→
are_positive_for
→
Object:
CD35
(Membrane Protein)
Original: cells#are positive for#CD21/ CD35/ and desmosomes ultrastructurally
#17953
middle Confidence
Subject:
cells
(cell)
→
are_positive_for
→
Object:
CD21
(Membrane Protein)
Original: cells#are positive for#CD21/ CD35/ and desmosomes ultrastructurally
#17942
middle Confidence
Subject:
melanoma_cells
(Tumor cells)
→
show
→
Object:
markedly_prominent_cellular_and_nuclear_atypia
(Cytological characteristics)
Original: melanoma cells#show#markedly prominent cellular and nuclear atypia
#17940
middle Confidence
Subject:
cytologic_criteria_of_synovial_sarcoma
(Diagnostic criteria)
→
were_defined_by
→
Object:
retrospective_examination
(Research Methods)
Original: Cytologic criteria of synovial sarcoma in fine-needle aspirates#were defined by#retrospective examination of 37 primary tumors
#17939
middle Confidence
Subject:
Patient
(patient)
→
presented_with
→
Object:
pericardial_effusion
(Clinical phenotype)
Original: A 35-year-old male#presented with#a mediastinal mass/ peripheral lymphadenopathy/ and pleural/pericardial effusion
#17938
middle Confidence
Subject:
Patient
(patient)
→
presented_with
→
Object:
pleural_effusion
(Clinical phenotype)
Original: A 35-year-old male#presented with#a mediastinal mass/ peripheral lymphadenopathy/ and pleural/pericardial effusion
#17937
middle Confidence
Subject:
Patient
(patient)
→
presented_with
→
Object:
peripheral_lymphadenopathy
(Clinical phenotype)
Original: A 35-year-old male#presented with#a mediastinal mass/ peripheral lymphadenopathy/ and pleural/pericardial effusion
#17936
middle Confidence
Subject:
Patient
(patient)
→
presented_with
→
Object:
mediastinal_mass
(Clinical phenotype)
Original: A 35-year-old male#presented with#a mediastinal mass/ peripheral lymphadenopathy/ and pleural/pericardial effusion
#17934
middle Confidence
Subject:
SSA
(Pathological type)
→
showed
→
Object:
architectural_abnormality_in_crypts
(Abnormal tissue structure)
Original: Major histological features in SSA#were#architectural abnormality in crypts
#17916
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
suggested
→
Object:
metastatic_tumor
(Tumor type)
Original: cytologic findings#suggested#rhabdomyosarcoma/ teratoma/ neuroblastoma/ malignant mesenchymoma/ pleuropulmonary blastoma/ and metastatic tumor
#17915
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
suggested
→
Object:
pleuropulmonary_blastoma
(Tumor type)
Original: cytologic findings#suggested#rhabdomyosarcoma/ teratoma/ neuroblastoma/ malignant mesenchymoma/ pleuropulmonary blastoma/ and metastatic tumor
#17914
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
suggested
→
Object:
malignant_mesenchymoma
(Tumor type)
Original: cytologic findings#suggested#rhabdomyosarcoma/ teratoma/ neuroblastoma/ malignant mesenchymoma/ pleuropulmonary blastoma/ and metastatic tumor
#17913
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
suggested
→
Object:
neuroblastoma
(Tumor type)
Original: cytologic findings#suggested#rhabdomyosarcoma/ teratoma/ neuroblastoma/ malignant mesenchymoma/ pleuropulmonary blastoma/ and metastatic tumor
#17912
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
suggested
→
Object:
teratoma
(Tumor type)
Original: cytologic findings#suggested#rhabdomyosarcoma/ teratoma/ neuroblastoma/ malignant mesenchymoma/ pleuropulmonary blastoma/ and metastatic tumor
#17911
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
suggested
→
Object:
rhabdomyosarcoma
(Tumor type)
Original: cytologic findings#suggested#rhabdomyosarcoma/ teratoma/ neuroblastoma/ malignant mesenchymoma/ pleuropulmonary blastoma/ and metastatic tumor
#17910
middle Confidence
Subject:
primary_cutaneous_mucoepidermoid_carcinoma
(Tumor type)
→
should_be_evaluated_for
→
Object:
possible_metastases
(Tumor metastasis)
Original: patients with primary cutaneous mucoepidermoid carcinoma#should be evaluated for#possible metastases
#17909
middle Confidence
Subject:
findings
(Test results)
→
are_compatible_with
→
Object:
metastatic_adenocarcinoma
(Tumor type)
Original: findings#are compatible with#metastatic adenocarcinoma
#17908
middle Confidence
Subject:
atypical_epithelioid_cells
(Cell Type)
→
demonstrate
→
Object:
scattered_mucin_deposition
(Cell morphology)
Original: atypical epithelioid cells#demonstrate#pleomorphism/ medium to prominent nucleoli/ and scattered mucin deposition
#17907
middle Confidence
Subject:
atypical_epithelioid_cells
(Cell Type)
→
demonstrate
→
Object:
medium_to_prominent_nucleoli
(Cell morphology)
Original: atypical epithelioid cells#demonstrate#pleomorphism/ medium to prominent nucleoli/ and scattered mucin deposition
#17906
middle Confidence
Subject:
atypical_epithelioid_cells
(Cell Type)
→
demonstrate
→
Object:
Pleomorphism
(Cell morphology)
Original: atypical epithelioid cells#demonstrate#pleomorphism/ medium to prominent nucleoli/ and scattered mucin deposition
#17902
middle Confidence
Subject:
cytologic_criteria
(Cytological criteria)
→
predictions
→
Object:
adenocarcinoma_in_situ
(Tumor diseases)
Original: adenocarcinoma in situ (AIS)#is predicted by#cytologic criteria
#17901
middle Confidence
Subject:
liver_cells
(Hepatocytes)
→
in_hepatocellular_carcinoma
→
Object:
small_cytoplasmic_vacuoles
(Cell phenotype)
Original: Liver cells in hepatocellular carcinoma#are characterized by#a high nucleus/cytoplasm ratio/ large cell diameters/ increased nucleoli/ and small cytoplasmic vacuoles
#17900
middle Confidence
Subject:
liver_cells
(Hepatocytes)
→
in_hepatocellular_carcinoma
→
Object:
increased_nucleoli
(Cell phenotype)
Original: Liver cells in hepatocellular carcinoma#are characterized by#a high nucleus/cytoplasm ratio/ large cell diameters/ increased nucleoli/ and small cytoplasmic vacuoles
#17899
middle Confidence
Subject:
liver_cells
(Hepatocytes)
→
in_hepatocellular_carcinoma
→
Object:
large_cell_diameters
(Cell phenotype)
Original: Liver cells in hepatocellular carcinoma#are characterized by#a high nucleus/cytoplasm ratio/ large cell diameters/ increased nucleoli/ and small cytoplasmic vacuoles
#17898
middle Confidence
Subject:
liver_cells
(Hepatocytes)
→
in_hepatocellular_carcinoma
→
Object:
high_nucleus_cytoplasm_ratio
(Cell phenotype)
Original: Liver cells in hepatocellular carcinoma#are characterized by#a high nucleus/cytoplasm ratio/ large cell diameters/ increased nucleoli/ and small cytoplasmic vacuoles
#17893
middle Confidence
Subject:
tumor_cells
(Cell Type)
→
show
→
Object:
focal_immunoreactivity_for_desmin
(Protein expression characteristics)
Original: tumor cells#show#focal immunoreactivity for desmin
#17889
middle Confidence
Subject:
orbital_meningiomas
(Tumor type)
→
present_with
→
Object:
orbital_mass
(Disease phenotype)
Original: orbital meningiomas#present with#orbital mass
#17888
middle Confidence
Subject:
malignancy
(Disease status)
→
is_associated_with
→
Object:
adjacent_high-grade_prostatic_intraepithelial_neoplasia
(Pathological conditions)
Original: malignancy#is associated with#adjacent high-grade prostatic intraepithelial neoplasia
#17887
middle Confidence
Subject:
Intravascular_lymphomatosis
(Tumor)
→
is_diagnosed_at
→
Object:
postmortem_examination
(Pathological examination)
Original: Intravascular lymphomatosis#is diagnosed at#postmortem examination
#17886
middle Confidence
Subject:
73-year-old_woman
(Patient characteristics)
→
presents_with
→
Object:
chest_wall_nodule
(Tumor phenotype)
Original: 73-year-old woman#presented with#chest wall nodule near site of prior mastectomy
#17885
middle Confidence
Subject:
RDD_histiocytes
(Histiocytes)
→
show_positive_immunostaining_for
→
Object:
CCND1
(Cell cycle proteins)
Original: RDD histiocytes#show positive immunostaining for#CD68/ CD163/ S100/ OCT-2/ Cyclin D1
#17884
middle Confidence
Subject:
RDD_histiocytes
(Histiocytes)
→
show_positive_immunostaining_for
→
Object:
2-Oct
(Transcription Factors)
Original: RDD histiocytes#show positive immunostaining for#CD68/ CD163/ S100/ OCT-2/ Cyclin D1
#17812
middle Confidence
Subject:
Preoperative_FNA
(Diagnostic techniques)
→
was_performed_on
→
Object:
CVPTC_patients
(patient)
Original: Preoperative FNA#was performed on#5 patients diagnosed with CVPTC
#17790
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
p53_protein
(Tumor suppressor proteins)
Original: tumor cells#are positive for#p53 protein
#17782
middle Confidence
Subject:
cyclin_staining
(Cell cycle markers)
→
may_facilitate
→
Object:
cytologic_diagnosis
(Cytological diagnosis)
Original: selective use of cyclin staining#may facilitate#cytologic diagnoses
#17777
middle Confidence
Subject:
large_cell_neuroendocrine_carcinoma
(Tumor type)
→
diagnosed_by
→
Object:
bronchial_brush_cytology
(Pathology Detection Technology)
Original: Large cell neuroendocrine carcinomas#can be diagnosed preoperatively by#bronchial brush cytology using reliable parameters
#17750
middle Confidence
Subject:
clear_cell_sarcoma
(Tumor type)
→
is_distinguished_from
→
Object:
metastatic_melanoma
(Tumor type)
Original: Distinction of clear cell sarcoma#from#metastatic melanoma
#17737
middle Confidence
Subject:
Hurthle_cells
(Tumor cell subtype)
→
are_encountered_in
→
Object:
thyroid_FNAC_smears
(Clinical test samples)
Original: Hurthle cells#are encountered in#thyroid fine needle aspiration cytology (FNAC) smears
#17732
middle Confidence
Subject:
pulmonary_carcinoid_tumor
(Tumor type)
→
diagnosed_by
→
Object:
immunohistochemical_method
(Diagnostic Methods)
Original: Pulmonary carcinoid tumors#are diagnosed by#morphologic and immunohistochemical methods
#17731
middle Confidence
Subject:
pulmonary_carcinoid_tumor
(Tumor type)
→
diagnosed_by
→
Object:
morphologic_method
(Diagnostic Methods)
Original: Pulmonary carcinoid tumors#are diagnosed by#morphologic and immunohistochemical methods
#17704
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
shows
→
Object:
immunolabeling_for_other_markers
(Protein expression)
Original: tumor cells#show#strong and diffuse cytoplasmic immunolabeling for vimentin and other markers
#17677
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_associated_with
→
Object:
large_thoracic_mass
(Tumor phenotype)
Original: NUT carcinoma#is associated with#large thoracic mass/ lymph nodes/ bone/ or pleural metastases
#17649
middle Confidence
Subject:
Immunohistochemistry
(Detection Technology)
→
helpful_for
→
Object:
sebaceous_differentiation
(Differentiation phenotype)
Original: To detect sebaceous differentiation#it would be helpful#to focus on holocrine secretion and immunohistochemistry
#17648
middle Confidence
Subject:
holocrine_secretion
(Secretion method)
→
helpful_for
→
Object:
sebaceous_differentiation
(Differentiation phenotype)
Original: To detect sebaceous differentiation#it would be helpful#to focus on holocrine secretion and immunohistochemistry
#17641
middle Confidence
Subject:
Ultrastructural_features
(Ultrastructural characteristics)
→
are_used_for
→
Object:
acute_leukemia_evaluation
(Disease diagnosis)
Original: Morphologic/ cytochemical/ and ultrastructural features#are used for#acute leukemia evaluation
#17640
middle Confidence
Subject:
Cytochemical_features
(Cytochemical characteristics)
→
are_used_for
→
Object:
acute_leukemia_evaluation
(Disease diagnosis)
Original: Morphologic/ cytochemical/ and ultrastructural features#are used for#acute leukemia evaluation
#17639
middle Confidence
Subject:
Morphologic_features
(Cell morphology)
→
are_used_for
→
Object:
acute_leukemia_evaluation
(Disease diagnosis)
Original: Morphologic/ cytochemical/ and ultrastructural features#are used for#acute leukemia evaluation
#17636
middle Confidence
Subject:
Cytological_features_of_melanoma
(Cell morphology)
→
aids_in
→
Object:
cytological_diagnosis
(Cytological diagnosis)
Original: Prior clinical history and cytological features of melanoma#aids in#cytological diagnoses
#17635
middle Confidence
Subject:
Prior_clinical_history
(Clinical history)
→
aids_in
→
Object:
cytological_diagnosis
(Cytological diagnosis)
Original: Prior clinical history and cytological features of melanoma#aids in#cytological diagnoses
#17634
middle Confidence
Subject:
nuclear_irregularity
(Nuclear irregularity)
→
were_recorded_and_scored
→
Object:
LP_slide_review
(Technical Process)
Original: Nucleoli/ nuclear grooving/ overlapping/ intranuclear inclusion/ and nuclear irregularity#were recorded and scored#on each case based on LP slide review
#17633
middle Confidence
Subject:
intranuclear_inclusion
(Intranuclear inclusion bodies)
→
were_recorded_and_scored
→
Object:
LP_slide_review
(Technical Process)
Original: Nucleoli/ nuclear grooving/ overlapping/ intranuclear inclusion/ and nuclear irregularity#were recorded and scored#on each case based on LP slide review
#17632
middle Confidence
Subject:
overlapping
(Nuclear overlap)
→
were_recorded_and_scored
→
Object:
LP_slide_review
(Technical Process)
Original: Nucleoli/ nuclear grooving/ overlapping/ intranuclear inclusion/ and nuclear irregularity#were recorded and scored#on each case based on LP slide review
#17631
middle Confidence
Subject:
nuclear_grooving
(Nuclear groove)
→
were_recorded_and_scored
→
Object:
LP_slide_review
(Technical Process)
Original: Nucleoli/ nuclear grooving/ overlapping/ intranuclear inclusion/ and nuclear irregularity#were recorded and scored#on each case based on LP slide review
#17630
middle Confidence
Subject:
nucleoli
(Nucleolus)
→
were_recorded_and_scored
→
Object:
LP_slide_review
(Technical Process)
Original: Nucleoli/ nuclear grooving/ overlapping/ intranuclear inclusion/ and nuclear irregularity#were recorded and scored#on each case based on LP slide review
#17629
middle Confidence
Subject:
atypical_cells
(Abnormal cells)
→
contain
→
Object:
single_macronucleolus
(Nucleolus)
Original: atypical cells#contain#a single macronucleolus with coarsely granular chromatin
#17628
middle Confidence
Subject:
cytological_parameters
(Cytological parameters)
→
are_related_to
→
Object:
marker_expression
(Molecular marker expression)
Original: cytological parameters#are related to#markers' expression
#17607
middle Confidence
Subject:
histologic_examination_of_uterus
(Histological examination)
→
revealed
→
Object:
typical_histologic_findings_of_LESS
(Histological characteristics)
Original: histologic examination of the uterus#revealed#typical histologic findings of LESS
#17606
middle Confidence
Subject:
Peripheral_blood_smears
(Blood smear)
→
were_reviewed_in
→
Object:
patients_with_BNLs
(patient)
Original: Peripheral blood smears#were reviewed in#patients affected by PPBL or harboring BNLs
#17605
middle Confidence
Subject:
Peripheral_blood_smears
(Blood smear)
→
were_reviewed_in
→
Object:
patients_with_PPBL
(patient)
Original: Peripheral blood smears#were reviewed in#patients affected by PPBL or harboring BNLs
#17603
middle Confidence
Subject:
Nodal lymphoma cells
(Tumor cells)
→
expresses
→
Object:
B-cell monotypic kappa light chain
(Immunoglobulin light chain)
Original: Nodal lymphoma cells#expressed#B-cell monotypic kappa light chain
#17598
middle Confidence
Subject:
Atypical_lymphoid_cells
(Abnormal lymphocytes)
→
show
→
Object:
pleomorphic_nuclei
(Nuclear abnormalities)
Original: Atypical lymphoid cells#show#large mitotic cells with pleomorphic nuclei
#17597
middle Confidence
Subject:
Atypical_lymphoid_cells
(Abnormal lymphocytes)
→
show
→
Object:
large_mitotic_cells
(Cell morphology)
Original: Atypical lymphoid cells#show#large mitotic cells with pleomorphic nuclei
#17594
middle Confidence
Subject:
lesions
(Lesions)
→
were_excluded_with
→
Object:
cytoarchitectural_patterns_of_intraductal_carcinoma
(Organizational structure characteristics)
Original: lesions#were excluded with#cytoarchitectural patterns of intraductal carcinoma
#17593
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed
→
Object:
diffuse_staining_of_vimentin
(Protein expression)
Original: tumor cells#showed#diffuse staining of vimentin
#17568
middle Confidence
Subject:
female_patient
(Patient characteristics)
→
presented_with
→
Object:
rapidly_increasing_breast_mass
(Clinical symptoms)
Original: patient#presented with#a mass in her right breast that rapidly increased in size over 2 months
#17561
middle Confidence
Subject:
Fine_needle_aspirate
(Diagnostic techniques)
→
presents_cytologic_findings_of
→
Object:
functioning_parathyroid_carcinoma
(Tumor diseases)
Original: Fine needle aspirate#presents cytologic findings of#a functioning parathyroid carcinoma
#17560
middle Confidence
Subject:
Cytologic_features
(Cytological characteristics)
→
are_reported_for
→
Object:
functioning_parathyroid_carcinoma
(Tumor diseases)
Original: Cytologic features#are reported for#a functioning parathyroid carcinoma
#17558
middle Confidence
Subject:
Atypical_meningiomas
(Tumor subtype)
→
are_defined_by
→
Object:
cytologic_findings
(Cytological characteristics)
Original: Atypical meningiomas#are defined by#high cellularity/ focal necrosis/ uninterrupted growth pattern/ and certain cytologic findings
#17557
middle Confidence
Subject:
Atypical_meningiomas
(Tumor subtype)
→
are_defined_by
→
Object:
uninterrupted_growth_pattern
(Cell behavior characteristics)
Original: Atypical meningiomas#are defined by#high cellularity/ focal necrosis/ uninterrupted growth pattern/ and certain cytologic findings
#17556
middle Confidence
Subject:
Atypical_meningiomas
(Tumor subtype)
→
are_defined_by
→
Object:
focal_necrosis
(Cell morphology)
Original: Atypical meningiomas#are defined by#high cellularity/ focal necrosis/ uninterrupted growth pattern/ and certain cytologic findings
#17555
middle Confidence
Subject:
Atypical_meningiomas
(Tumor subtype)
→
are_defined_by
→
Object:
high_cellularity
(Cell morphology)
Original: Atypical meningiomas#are defined by#high cellularity/ focal necrosis/ uninterrupted growth pattern/ and certain cytologic findings
#17552
middle Confidence
Subject:
specific_features
(Tissue morphology)
→
correlated_with
→
Object:
pathological_aspects_of_adrenals
(Disease phenotype)
Original: Specific features#correlated with#pathological aspects of the adrenals
#17551
middle Confidence
Subject:
cytomorphological_features
(Cell morphology)
→
are_enough_to
→
Object:
diagnose_MCC
(Disease diagnosis)
Original: cytomorphological features and ICC panel#are enough to#diagnose MCC
#17534
middle Confidence
Subject:
preoperative_FNAC
(Cytology)
→
showed
→
Object:
high_cellularity_with_clusters_of_tumor_cells_on_abundant_necrotic_background
(Cytological manifestations)
Original: Preoperative FNAC#showed#high cellularity with clusters of tumor cells on an abundant necrotic background
#17533
middle Confidence
Subject:
surgical_resection
(Surgery)
→
showed
→
Object:
atypical_proliferation_of_plasmacytoid_cells
(Cytological manifestations)
Original: Surgical resection#showed#markedly atypical/ large singly dispersed or cohesive proliferation of plasmacytoid cells
#17532
middle Confidence
Subject:
MRI
(Imaging tests)
→
shows
→
Object:
multiple_lesions_in_right_cerebral_hemisphere
(Imaging findings)
Original: MRI#showed#multiple lesions in the right cerebral hemisphere
#17531
middle Confidence
Subject:
antibody_panel
(Antibody Combination)
→
serves_as
→
Object:
diagnosis_of_myofibrosarcoma
(Diagnosis conclusion)
Original: A panel of antibodies including �?smooth muscle actin/ desmin/ and h-caldesmon#serves as#a practical way of diagnosing myofibrosarcoma
#17527
middle Confidence
Subject:
immunohistochemical_staining
(Detection Technology)
→
shows
→
Object:
CD56_positive
(Protein markers)
Original: Immunohistochemical staining#showed#at least three neuroendocrine markers (NSE/ CgA/ Syn and CD56) were positive
#17526
middle Confidence
Subject:
immunohistochemical_staining
(Detection Technology)
→
shows
→
Object:
Syn_positive
(Protein markers)
Original: Immunohistochemical staining#showed#at least three neuroendocrine markers (NSE/ CgA/ Syn and CD56) were positive
#17525
middle Confidence
Subject:
immunohistochemical_staining
(Detection Technology)
→
shows
→
Object:
CgA_positive
(Protein markers)
Original: Immunohistochemical staining#showed#at least three neuroendocrine markers (NSE/ CgA/ Syn and CD56) were positive
#17524
middle Confidence
Subject:
immunohistochemical_staining
(Detection Technology)
→
shows
→
Object:
NSE_positive
(Protein markers)
Original: Immunohistochemical staining#showed#at least three neuroendocrine markers (NSE/ CgA/ Syn and CD56) were positive
#17485
middle Confidence
Subject:
CEA
(Tumor markers)
→
is_detected_in
→
Object:
gastric_carcinoma
(disease)
Original: Gastric carcinoma biopsy specimens#compared for#abnormal histologic features/ type of intestinal metaplasia/ and presence of CEA
#17466
middle Confidence
Subject:
CD133
(Cell surface markers)
→
is_known_marker_for
→
Object:
Prostatic_stem_cells
(Stem Cells)
Original: Prostatic stem cells#were studied for#their known marker CD133 in tissue sections
#17435
middle Confidence
Subject:
immunophenotype_analysis
(Diagnostic analysis)
→
showed
→
Object:
negativity_for_cytokeratin_20
(Protein marker expression)
Original: immunophenotype analysis#showed#positivity for cytokeratin but negative cytokeratin 20 stains
#17434
middle Confidence
Subject:
immunophenotype_analysis
(Diagnostic analysis)
→
showed
→
Object:
positivity_for_cytokeratin
(Protein marker expression)
Original: immunophenotype analysis#showed#positivity for cytokeratin but negative cytokeratin 20 stains
#17433
middle Confidence
Subject:
epithelioid_appearance_of_neoplastic_cells
(Cell morphology)
→
suggested
→
Object:
recurrence_of_primary_carcinoma
(Tumor recurrence)
Original: The epithelioid appearance of neoplastic cells#suggested#a recurrence of primary carcinoma
#17431
middle Confidence
Subject:
EWSR1-PATZ1_fusion_positive_sarcomas
(Tumor disease subtype)
→
exhibit
→
Object:
overlapping_histologic_features
(Histological characteristics)
Original: EWSR1-PATZ1 fusion positive sarcomas#exhibit#overlapping histologic features
#17427
middle Confidence
Subject:
Nuclei
(Nucleus)
→
affect
→
Object:
cytological_diagnosis
(Diagnostic Process)
Original: Nuclear findings#affect#cytological diagnosis and prognostic significance
#17425
middle Confidence
Subject:
metastatic_tumor_cells
(Tumor cells)
→
express
→
Object:
CD44
(protein)
Original: Metastatic tumor cells#express#bcl-2 and CD44
#17424
middle Confidence
Subject:
metastatic_tumor_cells
(Tumor cells)
→
express
→
Object:
BCL2
(protein)
Original: Metastatic tumor cells#express#bcl-2 and CD44
#17412
middle Confidence
Subject:
papillae
(Organizational Structure)
→
proliferate_in
→
Object:
nephrogenic_adenoma
(disease)
Original: Nephrogenic adenoma#is characterized by#a circumscribed proliferation of tubules/ cysts/ and papillae lined by low cuboidal to columnar epithelium
#17411
middle Confidence
Subject:
cysts
(Organizational Structure)
→
proliferate_in
→
Object:
nephrogenic_adenoma
(disease)
Original: Nephrogenic adenoma#is characterized by#a circumscribed proliferation of tubules/ cysts/ and papillae lined by low cuboidal to columnar epithelium
#17410
middle Confidence
Subject:
tubules
(Organizational Structure)
→
proliferate_in
→
Object:
nephrogenic_adenoma
(disease)
Original: Nephrogenic adenoma#is characterized by#a circumscribed proliferation of tubules/ cysts/ and papillae lined by low cuboidal to columnar epithelium
#17408
middle Confidence
Subject:
CD34
(Cell markers)
→
is_positive_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: Neoplastic cells#were positive for#Ulex Europaeus/ Factor VIII-related antigen/ and CD34
#17390
middle Confidence
Subject:
bone_marrow_biopsy
(Histological examination)
→
shows_involvement_of
→
Object:
infiltration_pattern
(Tissue microenvironment characteristics)
Original: Bone marrow biopsy#shows involvement of#different degree and pattern
#17389
middle Confidence
Subject:
epithelioid_angiosarcoma_of_the_skin
(Tumor)
→
shows
→
Object:
unusual_morphologic_features
(Tumor cell morphology)
Original: epithelioid angiosarcoma of the skin#shows#a clinicopathologic spectrum and unusual morphologic features
#17388
middle Confidence
Subject:
epithelioid_angiosarcoma_of_the_skin
(Tumor)
→
shows
→
Object:
clinicopathologic_spectrum
(Disease phenotype)
Original: epithelioid angiosarcoma of the skin#shows#a clinicopathologic spectrum and unusual morphologic features
#17387
middle Confidence
Subject:
cytologic_features_of_SMARCA4_deficient_thoracic_sarcoma
(Tumor cell morphology)
→
may_promote
→
Object:
molecular_testing
(Molecular testing)
Original: cytologic features of SMARCA4-deficient thoracic sarcoma#may promote#additional immunological or molecular testing
#17386
middle Confidence
Subject:
cytologic_features_of_SMARCA4_deficient_thoracic_sarcoma
(Tumor cell morphology)
→
may_promote
→
Object:
immunological_testing
(Molecular testing)
Original: cytologic features of SMARCA4-deficient thoracic sarcoma#may promote#additional immunological or molecular testing
#17378
middle Confidence
Subject:
pancreatic_juice_cytology_during_ERP_or_surgery
(Cytology)
→
is_useful_in
→
Object:
diagnosing_pancreatic_cancers
(diagnosis)
Original: Pancreatic juice cytology during ERP or surgery#is useful in#diagnosing pancreatic cancers
#17371
middle Confidence
Subject:
classification_schemes
(Diagnostic criteria)
→
evaluate
→
Object:
lymph_nodes_in_CTCL_patients
(Lymph nodes)
Original: classification schemes#evaluate#lymph nodes in CTCL patients
#17370
middle Confidence
Subject:
fine_needle_aspiration
(Cytological techniques)
→
reveals
→
Object:
primitive_neoplastic_cells_with_high_NC_ratio
(Cell morphological characteristics)
Original: fine needle aspiration#reveals#primitive neoplastic cells with high nuclear-cytoplasmic ratio
#17360
middle Confidence
Subject:
Diagnosis_of_metanephric_adenoma
(Diagnostic behavior)
→
depends_on
→
Object:
molecular_features
(Molecular characteristics)
Original: Diagnosis of metanephric adenoma#depends on#morphological/ immunohistochemical/ and molecular features
#17359
middle Confidence
Subject:
Diagnosis_of_metanephric_adenoma
(Diagnostic behavior)
→
depends_on
→
Object:
immunohistochemical_features
(Immunohistochemical characteristics)
Original: Diagnosis of metanephric adenoma#depends on#morphological/ immunohistochemical/ and molecular features
#17358
middle Confidence
Subject:
Diagnosis_of_metanephric_adenoma
(Diagnostic behavior)
→
depends_on
→
Object:
morphological_features
(Morphological characteristics)
Original: Diagnosis of metanephric adenoma#depends on#morphological/ immunohistochemical/ and molecular features
#17357
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
is_associated_with
→
Object:
molecular_pathological_characteristics
(Molecular markers)
Original: Metanephric adenoma#is associated with#immunohistochemical and molecular pathological characteristics
#17356
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
is_associated_with
→
Object:
immunohistochemical_characteristics
(Molecular markers)
Original: Metanephric adenoma#is associated with#immunohistochemical and molecular pathological characteristics
#17355
middle Confidence
Subject:
Rhabdoid tumor of the kidney
(Tumor type)
→
is_characterized_by
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Rhabdoid tumor of the kidney#is characterized by#monomorphic cells with abundant cytoplasm/ eccentric nuclei/ and prominent nucleoli
#17354
middle Confidence
Subject:
Rhabdoid tumor of the kidney
(Tumor type)
→
is_characterized_by
→
Object:
eccentric_nuclei
(Cell morphology)
Original: Rhabdoid tumor of the kidney#is characterized by#monomorphic cells with abundant cytoplasm/ eccentric nuclei/ and prominent nucleoli
#17353
middle Confidence
Subject:
Rhabdoid tumor of the kidney
(Tumor type)
→
is_characterized_by
→
Object:
abundant_cytoplasm
(Cell morphology)
Original: Rhabdoid tumor of the kidney#is characterized by#monomorphic cells with abundant cytoplasm/ eccentric nuclei/ and prominent nucleoli
#17352
middle Confidence
Subject:
Rhabdoid tumor of the kidney
(Tumor type)
→
is_characterized_by
→
Object:
monomorphic_cells
(Cell Type)
Original: Rhabdoid tumor of the kidney#is characterized by#monomorphic cells with abundant cytoplasm/ eccentric nuclei/ and prominent nucleoli
#17350
middle Confidence
Subject:
mediastinal_seminoma
(Tumor tissue)
→
is_diagnosed_by
→
Object:
cytological_examination_of_cystic_fluid
(Detection Methods)
Original: Mediastinal seminoma#is diagnosed by#cytological examination of cystic fluid
#17336
middle Confidence
Subject:
axillary_tumor_location
(Anatomical location of tumor)
→
is_associated_with
→
Object:
apocrine_carcinoma_characteristics
(Disease phenotype)
Original: Tumor location in axilla#matched#apocrine carcinoma characteristics
#17326
middle Confidence
Subject:
moderately_differentiated_tumor
(Tumor grade)
→
reveals
→
Object:
wider_range_of_nucleus_size
(Nuclear characteristics)
Original: moderately differentiated tumor#reveals#a wider range of nucleus size and large nucleoli
#17325
middle Confidence
Subject:
moderately_differentiated_tumor
(Tumor grade)
→
reveals
→
Object:
large_nucleoli
(Histological characteristics)
Original: moderately differentiated tumor#reveals#a wider range of nucleus size and large nucleoli
#17287
middle Confidence
Subject:
cytological_findings
(Cytological characteristics)
→
were_closely_related_with
→
Object:
differentiation_degree_of_endocervical_adenocarcinoma
(Tumor grade)
Original: Cytological findings#were closely related with#differentiation degree of endocervical adenocarcinoma
#17244
middle Confidence
Subject:
Apoptosis
(Cellular Processes)
→
is_evaluated_by
→
Object:
activated_caspase-3_examination
(Detection Technology)
Original: Apoptosis#is evaluated by#Hoechst 33258 staining and activated caspase-3 examination
#17243
middle Confidence
Subject:
Apoptosis
(Cellular Processes)
→
is_evaluated_by
→
Object:
Hoechst_33258_staining
(Detection Technology)
Original: Apoptosis#is evaluated by#Hoechst 33258 staining and activated caspase-3 examination
#17201
middle Confidence
Subject:
MKI67
(Cell proliferation markers)
→
is_upregulated_in
→
Object:
mitotic_cells
(Splinter Cell)
Original: Highest Ki-67 levels#were revealed in#mitotic cells
#17170
middle Confidence
Subject:
p120
(Cell adhesion proteins)
→
is_evaluated_in
→
Object:
lung_cancer_tissues
(Tumor tissue)
Original: p120 expression levels#are evaluated in#human lung cancer tissues
#17132
middle Confidence
Subject:
ORF-2p
(Transposon protein)
→
has_been_detected_in
→
Object:
human_cancers
(Tumor)
Original: ORF-1p and ORF-2p#have been detected in#human cancers
#17131
middle Confidence
Subject:
ORF-1p
(Transposon protein)
→
has_been_detected_in
→
Object:
human_cancers
(Tumor)
Original: ORF-1p and ORF-2p#have been detected in#human cancers
#17083
middle Confidence
Subject:
Cyclin_D1
(Cell cycle proteins)
→
is_expressed_in
→
Object:
SACC_patient_specimens
(Clinical samples)
Original: Cyclin D1#is expressed in#SACC patient specimens
#17082
middle Confidence
Subject:
Beta-catenin
(Signal transduction proteins)
→
is_expressed_in
→
Object:
SACC_patient_specimens
(Clinical samples)
Original: Beta-catenin#is expressed in#SACC patient specimens
#17081
middle Confidence
Subject:
PIN1
(Isomerase)
→
is_expressed_in
→
Object:
SACC_patient_specimens
(Clinical samples)
Original: Pin1#is expressed in#SACC patient specimens
#16943
middle Confidence
Subject:
prominent_nucleoli_in_melanoma_cells
(Cellular substructure)
→
are_observed_in
→
Object:
nodular_melanoma
(Disease phenotype)
Original: melanoma cells with prominent nucleoli#are observed in#nodular melanoma
#16911
middle Confidence
Subject:
immunostaining_of_biopsy_material
(Diagnostic techniques)
→
is_feasible_for
→
Object:
ALK
(Receptor tyrosine kinases)
Original: Immunostaining of biopsy material#is feasible for#NPM-ALK and ALK proteins
#16910
middle Confidence
Subject:
immunostaining_of_biopsy_material
(Diagnostic techniques)
→
is_feasible_for
→
Object:
NPM-ALK
(Fusion Protein)
Original: Immunostaining of biopsy material#is feasible for#NPM-ALK and ALK proteins
#16741
middle Confidence
Subject:
Anaplastic_large_cell_lymphoma
(Tumor diseases)
→
is_a
→
Object:
neoplasm_of_activated_lymphocytes
(Tumor cell type)
Original: Anaplastic large cell lymphoma (ALCL)#is#a neoplasm of activated lymphocytes
#16728
middle Confidence
Subject:
5'ETS_rRNA_signal
(Molecular markers)
→
is_present_in
→
Object:
all_pathologic_stages
(Pathological staging)
Original: Increase in 5'ETS rRNA signal#is present in#all Gleason scores and pathologic stages
#16727
middle Confidence
Subject:
5'ETS_rRNA_signal
(Molecular markers)
→
is_present_in
→
Object:
all_Gleason_scores
(Pathological grading)
Original: Increase in 5'ETS rRNA signal#is present in#all Gleason scores and pathologic stages
#16689
middle Confidence
Subject:
AgNOR_staining
(Molecular detection technology)
→
distinguishes
→
Object:
cervical_intraepithelial_neoplasia
(Preneoplastic lesions)
Original: Ag-NOR staining technique for nucleolar organizer regions#distinguishes#benign proliferative reactions from cervical intra-epithelial neoplasia (CIN)
#16688
middle Confidence
Subject:
AgNOR_staining
(Molecular detection technology)
→
distinguishes
→
Object:
benign_proliferative_reactions
(Benign cell proliferation)
Original: Ag-NOR staining technique for nucleolar organizer regions#distinguishes#benign proliferative reactions from cervical intra-epithelial neoplasia (CIN)
#16683
middle Confidence
Subject:
Ag-NOR_staining_technique
(Histochemical analysis techniques)
→
differentiations
→
Object:
well_differentiated_carcinoma
(disease)
Original: Ag-NOR staining technique#is performed on#cases of different endometrial lesions to differentiate atypical hyperplasia from well-differentiated carcinoma
#16682
middle Confidence
Subject:
Ag-NOR_staining_technique
(Histochemical analysis techniques)
→
differentiations
→
Object:
atypical_hyperplasia
(disease)
Original: Ag-NOR staining technique#is performed on#cases of different endometrial lesions to differentiate atypical hyperplasia from well-differentiated carcinoma
#16681
middle Confidence
Subject:
Ag-NOR_staining_technique
(Histochemical analysis techniques)
→
is_performed_on
→
Object:
endometrial_lesions
(disease)
Original: Ag-NOR staining technique#is performed on#cases of different endometrial lesions to differentiate atypical hyperplasia from well-differentiated carcinoma
#16678
middle Confidence
Subject:
AgNOR_morphometric_analysis
(Histochemical analysis techniques)
→
is_applied_to
→
Object:
non-Hodgkin's_lymphomas
(disease)
Original: AgNOR morphometric analysis#is applied to#non-Hodgkin's lymphomas
#16662
middle Confidence
Subject:
C_EBPbeta
(Transcription Factors)
→
is_immunostained_in
→
Object:
radical_prostatectomy_slides
(Tissue sections)
Original: cytokeratin 5/ GSTP1/ c-MET/ C/EBPbeta/ Ki-67#are immunostained in#radical prostatectomy slides
#16661
middle Confidence
Subject:
c_MET
(Receptor tyrosine kinases)
→
is_immunostained_in
→
Object:
radical_prostatectomy_slides
(Tissue sections)
Original: cytokeratin 5/ GSTP1/ c-MET/ C/EBPbeta/ Ki-67#are immunostained in#radical prostatectomy slides
#16660
middle Confidence
Subject:
GSTP1
(Glutathione S-transferase)
→
is_immunostained_in
→
Object:
radical_prostatectomy_slides
(Tissue sections)
Original: cytokeratin 5/ GSTP1/ c-MET/ C/EBPbeta/ Ki-67#are immunostained in#radical prostatectomy slides
#16659
middle Confidence
Subject:
cytokeratin_5
(Cytoskeletal proteins)
→
is_immunostained_in
→
Object:
radical_prostatectomy_slides
(Tissue sections)
Original: cytokeratin 5/ GSTP1/ c-MET/ C/EBPbeta/ Ki-67#are immunostained in#radical prostatectomy slides
#16658
middle Confidence
Subject:
AgNORs_enumeration
(Molecular analysis parameters)
→
differentiations
→
Object:
malignant_testicular_teratoma
(Malignant tumor tissue)
Original: AgNORs enumeration#differentiates#benign and malignant testicular teratoma
#16657
middle Confidence
Subject:
AgNORs_enumeration
(Molecular analysis parameters)
→
differentiations
→
Object:
benign_testicular_teratoma
(Benign tumor tissue)
Original: AgNORs enumeration#differentiates#benign and malignant testicular teratoma
#16656
middle Confidence
Subject:
AgNORs_enumeration
(Molecular analysis parameters)
→
distinguishes
→
Object:
malignant_cells
(Tumor cells)
Original: AgNORs enumeration#distinguishes#reactive mesothelial cells from malignant cells
#16655
middle Confidence
Subject:
AgNORs_enumeration
(Molecular analysis parameters)
→
distinguishes
→
Object:
reactive_mesothelial_cells
(Mesothelial cells)
Original: AgNORs enumeration#distinguishes#reactive mesothelial cells from malignant cells
#16654
middle Confidence
Subject:
in_situ_carcinomas
(Histopathological type)
→
are_positive_for
→
Object:
GCDFP15
(Secretory proteins)
Original: in situ carcinomas#are positive for#ERs/ p53/ GCDFP-15
#16653
middle Confidence
Subject:
in_situ_carcinomas
(Histopathological type)
→
are_positive_for
→
Object:
p53
(Transcription Factors)
Original: in situ carcinomas#are positive for#ERs/ p53/ GCDFP-15
#16652
middle Confidence
Subject:
in_situ_carcinomas
(Histopathological type)
→
are_positive_for
→
Object:
ER
(Nuclear receptor proteins)
Original: in situ carcinomas#are positive for#ERs/ p53/ GCDFP-15
#16651
middle Confidence
Subject:
4.5_AgNORs_threshold
(Molecular analysis parameters)
→
identifies
→
Object:
carcinoma_cells
(Tumor cells)
Original: thresholds of 2.5 and 4.5 AgNORs#identify#mesothelioma and carcinoma cells
#16650
middle Confidence
Subject:
2.5_AgNORs_threshold
(Molecular analysis parameters)
→
identifies
→
Object:
mesothelioma_cells
(Tumor cells)
Original: thresholds of 2.5 and 4.5 AgNORs#identify#mesothelioma and carcinoma cells
#16631
middle Confidence
Subject:
immunostaining_markers
(Molecular diagnostic tools)
→
are_supportive_tools_for
→
Object:
histological_diagnosis
(Diagnostic Process)
Original: Immunostaining markers#are supportive tools for#histological diagnosis of GAFG
#16626
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
contributes_to
→
Object:
diagnosis_of_SGC_by_staining_for_AR441
(AR441 staining for diagnosis of SGC)
Original: immunohistochemistry#contributes to#diagnosis of SGC by staining for adipophilin or AR441
#16625
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
contributes_to
→
Object:
diagnosis_of_SGC_by_staining_for_adipophilin
(Diagnosis of SGC by lipoglobulin staining)
Original: immunohistochemistry#contributes to#diagnosis of SGC by staining for adipophilin or AR441
#16623
middle Confidence
Subject:
carcinomatous_tissue
(Cancer tissue)
→
shows
→
Object:
positive_reaction_of_ER
(ER positive reaction)
Original: Carcinomatous tissues#show#higher DNA content/ AgNOR content/ and positive reaction of CEA and ER than normal tissue
#16622
middle Confidence
Subject:
carcinomatous_tissue
(Cancer tissue)
→
shows
→
Object:
positive_reaction_of_CEA
(CEA positive reaction)
Original: Carcinomatous tissues#show#higher DNA content/ AgNOR content/ and positive reaction of CEA and ER than normal tissue
#16619
middle Confidence
Subject:
NORA_values
(Nucleolar organizer region related parameters)
→
confirm
→
Object:
parathyroid_lesions
(Parathyroid disease)
Original: NORA values#confirm#AgNOR analysis as an additional tool for parathyroid lesions
#16617
middle Confidence
Subject:
p53_staining
(Protein expression status)
→
is_positive_in
→
Object:
dysplasia_controls
(Control group)
Original: p53 staining#is positive in#100% of dysplasia controls
#16614
middle Confidence
Subject:
protein_over-expression
(Protein expression status)
→
is_found_in
→
Object:
carcinomas
(Tumor diseases)
Original: protein over-expression#is found in#carcinomas by A0485 and CB11 antibodies
#16605
middle Confidence
Subject:
transitional_papillomas_of_the_nose_with_malignant_change
(Disease phenotype)
→
are_distinguished_from
→
Object:
benign_counterparts
(Disease phenotype)
Original: Transitional papillomas of the nose showing malignant change#are distinguished from#benign counterparts using AgNOR counts
#16604
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
are_observed_in
→
Object:
oral_squamous_cell_carcinoma
(Disease phenotype)
Original: AgNORs#are observed in#hyperplasia/ papilloma/ and oral squamous cell carcinoma
#16603
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
are_observed_in
→
Object:
papilloma
(Disease phenotype)
Original: AgNORs#are observed in#hyperplasia/ papilloma/ and oral squamous cell carcinoma
#16602
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
are_observed_in
→
Object:
hyperplasia
(Disease phenotype)
Original: AgNORs#are observed in#hyperplasia/ papilloma/ and oral squamous cell carcinoma
#16598
middle Confidence
Subject:
AgNOR protein
(Nucleolus-associated protein)
→
is_detected_in
→
Object:
meningiomas
(Tumor tissue)
Original: AgNOR proteins#were demonstrated in#astrocytomas/ glioblastomas/ and meningiomas
#16597
middle Confidence
Subject:
AgNOR protein
(Nucleolus-associated protein)
→
is_detected_in
→
Object:
Glioblastomas
(Tumor tissue)
Original: AgNOR proteins#were demonstrated in#astrocytomas/ glioblastomas/ and meningiomas
#16596
middle Confidence
Subject:
AgNOR protein
(Nucleolus-associated protein)
→
is_detected_in
→
Object:
astrocytomas
(Tumor tissue)
Original: AgNOR proteins#were demonstrated in#astrocytomas/ glioblastomas/ and meningiomas
#16584
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizing region)
→
are_used_as
→
Object:
proliferation_markers
(Proliferation markers)
Original: Nucleolar organizer regions#are used as#markers in proliferation
#16581
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Fine needle aspiration biopsy)
→
was_performed_on
→
Object:
patients_with_SFT_of_pleura
(Patients with pleural SFT)
Original: Fine-needle aspiration biopsies#were performed on#patients with SFT of the pleura
#16560
middle Confidence
Subject:
AgNOR
(Nucleolar organizer region-associated silver stain)
→
was_studied_in
→
Object:
cutaneous_melanocytic_lesions
(Melanocytic skin lesions)
Original: AgNOR and Ki-67 immunoreactivity#were studied in#cutaneous melanocytic lesions
#16544
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
are_present_in
→
Object:
xanthogranulomatous_pyelonephritis
(Xanthogranulomatous pyelonephritis)
Original: Nucleolar organizer regions#are present in#kidney tumors and xanthogranulomatous pyelonephritis
#16543
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
are_present_in
→
Object:
kidney_tumors
(Kidney tumors)
Original: Nucleolar organizer regions#are present in#kidney tumors and xanthogranulomatous pyelonephritis
#16535
middle Confidence
Subject:
AgNOR
(Nucleolar Organizing Region-associated Protein)
→
is_a_marker_for
→
Object:
prostatic_carcinoma
(Prostate cancer)
Original: Nucleolar organizer regions (AgNORs)#are a marker for#prostatic carcinoma
#16529
middle Confidence
Subject:
gastric_carcinoma
(Tumor)
→
is_correlated_with
→
Object:
EGFR_expression
(Receptor protein expression)
Original: gastric carcinoma#is correlated with#prognostic indicators like AgNORs/ Ki 67 Labelling Index/ and EGFR expression
#16528
middle Confidence
Subject:
gastric_carcinoma
(Tumor)
→
is_correlated_with
→
Object:
Ki67_labelling_index
(Cell proliferation markers)
Original: gastric carcinoma#is correlated with#prognostic indicators like AgNORs/ Ki 67 Labelling Index/ and EGFR expression
#16527
middle Confidence
Subject:
gastric_carcinoma
(Tumor)
→
is_correlated_with
→
Object:
AgNORs
(Nucleolar organizing region)
Original: gastric carcinoma#is correlated with#prognostic indicators like AgNORs/ Ki 67 Labelling Index/ and EGFR expression
#16521
middle Confidence
Subject:
AgNORs
(Nucleolar Organizing Region-associated Protein)
→
has_diagnostic_significance_in
→
Object:
oral_squamous_cell_carcinoma
(disease)
Original: FDG-PET and AgNORs#have diagnostic significance in#oral squamous cell carcinoma
#16516
middle Confidence
Subject:
lymphocytes with satellite nucleoli
(Special phenotype lymphocytes)
→
were_found_in
→
Object:
leukemic_patients
(Patient population)
Original: lymphocytes with satellite nucleoli#were found in#leukemic patients
#16514
middle Confidence
Subject:
tumor_metabolism
(Tumor metabolism)
→
contributes_to
→
Object:
temperature_differences
(Temperature Difference)
Original: Tumor metabolism#contributes to#temperature differences
#16513
middle Confidence
Subject:
number_of_mitoses_and_nucleolar_size_staining
(Cell division and nucleolar characteristics)
→
correlate_with
→
Object:
thermographic_results
(Thermal imaging results)
Original: Number of mitoses/ size and staining of nucleoli#correlate with#thermographic results
#16512
middle Confidence
Subject:
cyto- and_histomorphological_characteristics
(Cell and tissue morphology)
→
correlate_with
→
Object:
thermographical_results_of_breast_carcinomas
(Thermal imaging diagnosis results)
Original: Metric/ cyto- and histomorphological characteristics#correlate with#thermographical results of 119 carcinomas of the breast
#16499
middle Confidence
Subject:
pleomorphic_adenomas_with_bizarre_neoplastic_cells
(Adenoma mutant cells)
→
should_be_distinguished_from
→
Object:
malignant_transformation
(Malignant transformation)
Original: Pleomorphic adenomas with bizarre neoplastic cells#should be distinguished from#malignant transformation
#16498
middle Confidence
Subject:
AgNORs
(Silver-stained nucleolar organizing region)
→
have
→
Object:
diagnostic_value_in_thyroid_nodules
(Diagnostic value of thyroid nodules)
Original: Argyrophilic nucleolar organizing regions (AgNORs)#have#diagnostic value in thyroid nodules
#16497
middle Confidence
Subject:
NOR_number
(NOR)
→
should_be_defined_by
→
Object:
histologic_pattern_discrimination
(Histological pattern identification)
Original: Number of NORs in pleomorphic adenomas#should be defined by#discriminating between histologic patterns
#16482
middle Confidence
Subject:
Non-hematopoietic_cells
(Parenchymal cells)
→
lacks_expression_of
→
Object:
CD45
(Cell markers)
Original: Neoplastic cells#were identified as#non-hematopoietic cells positive for CD56 and negative for CD45
#16481
middle Confidence
Subject:
Non-hematopoietic_cells
(Parenchymal cells)
→
expresses
→
Object:
CD56
(Cell markers)
Original: Neoplastic cells#were identified as#non-hematopoietic cells positive for CD56 and negative for CD45
#16480
middle Confidence
Subject:
syncytial_giant_cells
(Tumor cells)
→
lacks_expression_of
→
Object:
mucin
(Cell markers)
Original: SGCs#were positive for#AE1/AE3/ vimentin/ and epithelial membrane antigen and negative for CD68/ beta-human chorionic gonadotropin/ and mucin
#16479
middle Confidence
Subject:
syncytial_giant_cells
(Tumor cells)
→
lacks_expression_of
→
Object:
beta_human_chorianic_gonadotropin
(Cell markers)
Original: SGCs#were positive for#AE1/AE3/ vimentin/ and epithelial membrane antigen and negative for CD68/ beta-human chorionic gonadotropin/ and mucin
#16478
middle Confidence
Subject:
syncytial_giant_cells
(Tumor cells)
→
lacks_expression_of
→
Object:
CD68
(Cell markers)
Original: SGCs#were positive for#AE1/AE3/ vimentin/ and epithelial membrane antigen and negative for CD68/ beta-human chorionic gonadotropin/ and mucin
#16477
middle Confidence
Subject:
syncytial_giant_cells
(Tumor cells)
→
expresses
→
Object:
epithelial_membrane_antigen
(Cell markers)
Original: SGCs#were positive for#AE1/AE3/ vimentin/ and epithelial membrane antigen and negative for CD68/ beta-human chorionic gonadotropin/ and mucin
#16476
middle Confidence
Subject:
syncytial_giant_cells
(Tumor cells)
→
expresses
→
Object:
vimentin
(Cell markers)
Original: SGCs#were positive for#AE1/AE3/ vimentin/ and epithelial membrane antigen and negative for CD68/ beta-human chorionic gonadotropin/ and mucin
#16475
middle Confidence
Subject:
syncytial_giant_cells
(Tumor cells)
→
expresses
→
Object:
AE1/AE3
(Cell markers)
Original: SGCs#were positive for#AE1/AE3/ vimentin/ and epithelial membrane antigen and negative for CD68/ beta-human chorionic gonadotropin/ and mucin
#16443
middle Confidence
Subject:
Polymorphous_low_grade_adenocarcinoma
(Adenocarcinoma subtype)
→
was_described_as
→
Object:
clinicopathologic_entity
(Clinical pathological entities)
Original: Polymorphous low-grade adenocarcinoma (PLGA)#was initially described as#an established clinicopathologic entity
#16442
middle Confidence
Subject:
serous_neoplasm
(Serous tumors)
→
is_identified_in
→
Object:
peritoneal_fluid
(Body fluid specimens)
Original: serous neoplasms#are identified in#peritoneal fluids
#16441
middle Confidence
Subject:
nuclear_findings
(Nuclear manifestations)
→
are_diagnostic_for
→
Object:
adenoma_malignum
(Tumor type)
Original: nuclear findings#are thought to be#diagnostic characteristics of adenoma malignum
#16440
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
showed
→
Object:
budlike_nuclei
(budding nucleus)
Original: tumor cells#showed#intranuclear cytoplasmic inclusion bodies and lobate or budlike nuclei
#16439
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
showed
→
Object:
lobate_nuclei
(lobulated nuclei)
Original: tumor cells#showed#intranuclear cytoplasmic inclusion bodies and lobate or budlike nuclei
#16438
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
showed
→
Object:
intranuclear_cytoplasmic_inclusion_bodies
(Intracellular inclusion bodies)
Original: tumor cells#showed#intranuclear cytoplasmic inclusion bodies and lobate or budlike nuclei
#16437
middle Confidence
Subject:
tumor
(Tumor tissue)
→
is_characterized_by
→
Object:
large_epithelioid_melanocytes
(Cell Type)
Original: tumors#are characterized by#a nevus-like silhouette and cytologic composition of large epithelioid melanocytes
#16436
middle Confidence
Subject:
tumor
(Tumor tissue)
→
is_characterized_by
→
Object:
nevus_like_silhouette
(Pathological morphology)
Original: tumors#are characterized by#a nevus-like silhouette and cytologic composition of large epithelioid melanocytes
#16435
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
shows
→
Object:
granular_cytoplasm
(Granular cytoplasm)
Original: tumor cells#show#discohesion/ binucleation/ and granular cytoplasm
#16434
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
shows
→
Object:
binucleation
(Dual-core phenomenon)
Original: tumor cells#show#discohesion/ binucleation/ and granular cytoplasm
#16433
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
shows
→
Object:
discohesion
(Loss of cell connections)
Original: tumor cells#show#discohesion/ binucleation/ and granular cytoplasm
#16413
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD43
(Protein markers)
Original: tumor cells#were positive for#CD10/ Bcl-2/ Bcl-6/ and CD43
#16412
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
BCL6
(Protein markers)
Original: tumor cells#were positive for#CD10/ Bcl-2/ Bcl-6/ and CD43
#16411
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
BCL2
(Protein markers)
Original: tumor cells#were positive for#CD10/ Bcl-2/ Bcl-6/ and CD43
#16410
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD10
(Protein markers)
Original: tumor cells#were positive for#CD10/ Bcl-2/ Bcl-6/ and CD43
#16409
middle Confidence
Subject:
cutaneous_epithelioid_angiomatous_nodule
(Benign vascular lesions)
→
usually_presents_as
→
Object:
solitary_fast-growing_small_reddish_papulous_or_nodular_lesion
(Clinical phenotype)
Original: Cutaneous epithelioid angiomatous nodule#usually presents as#a solitary/ fast-growing/ small reddish papulous or nodular lesion on the trunk or limbs of adults
#16408
middle Confidence
Subject:
cutaneous_epithelioid_angiomatous_nodule
(Benign vascular lesions)
→
is
→
Object:
uncommon_benign_vascular_proliferation
(Pathological diagnosis)
Original: Cutaneous epithelioid angiomatous nodule#is#an uncommon benign vascular proliferation
#16407
middle Confidence
Subject:
tubular_carcinoma_of_the_breast
(Tumor diseases)
→
has
→
Object:
neoplastic_mimics
(Tumor artifact)
Original: tubular carcinoma of the breast#has#reactive and neoplastic mimics
#16406
middle Confidence
Subject:
tubular_carcinoma_of_the_breast
(Tumor diseases)
→
has
→
Object:
reactive_mimics
(Pathological reactive artifact)
Original: tubular carcinoma of the breast#has#reactive and neoplastic mimics
#16354
middle Confidence
Subject:
rectal_gland
(Glandular structure)
→
mimics
→
Object:
prostatic_adenocarcinoma
(Adenocarcinoma)
Original: Distorted rectal glands#can mimic#prostatic adenocarcinoma
#16353
middle Confidence
Subject:
malignant_cell
(Cell Type)
→
were_identifiable_in
→
Object:
effusion
(body fluid)
Original: Malignant cells#were identifiable in#effusion in all noncirrhotic cases
#16347
middle Confidence
Subject:
cytological_assessment_of_fluid
(Diagnostic techniques)
→
valuable_for
→
Object:
breast_implant_related_complications
(Disease phenotype)
Original: This case#emphasises#the value of cytological assessment of fluid around breast implants
#16345
middle Confidence
Subject:
Small_cell_morphology
(Cell morphology)
→
suggests
→
Object:
small_cell_neuroendocrine_tumor
(Tumor type)
Original: Small cell morphology#suggested#a possibility of small cell neuroendocrine tumor
#16318
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
inconspicuous_nucleolus
(Nuclear morphology)
Original: Tumors#showed#a sinusoidal and/or cohesive pattern with condensed chromatin and inconspicuous nucleolus
#16317
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
condensed_chromatin
(Nuclear morphology)
Original: Tumors#showed#a sinusoidal and/or cohesive pattern with condensed chromatin and inconspicuous nucleolus
#16316
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
cohesive_pattern
(Tumor tissue morphology)
Original: Tumors#showed#a sinusoidal and/or cohesive pattern with condensed chromatin and inconspicuous nucleolus
#16315
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
sinusoidal_pattern
(Tumor tissue morphology)
Original: Tumors#showed#a sinusoidal and/or cohesive pattern with condensed chromatin and inconspicuous nucleolus
#16314
middle Confidence
Subject:
metaplastic_proliferations
(Cellular Processes)
→
should_be_distinguished_from
→
Object:
aggressive_malignant_neoplasms
(Malignant tumors)
Original: metaplastic proliferations#should be distinguished from#aggressive malignant neoplasms
#16307
middle Confidence
Subject:
Southern_blotting
(Molecular detection technology)
→
revealed
→
Object:
TCR_rearrangement
(Gene rearrangement)
Original: Southern blotting#revealed#rearrangement of TCR
#16301
middle Confidence
Subject:
CD56
(NK cell markers)
→
is_expressed_on
→
Object:
T_cells
(Immune cells)
Original: Flow cytometry#showed#surface expression of CD2/ CD3/ CD7 (dim)/ CD8/ and CD56
#16300
middle Confidence
Subject:
CD7
(T cell surface molecules)
→
is_dimly_expressed_on
→
Object:
T_cells
(Immune cells)
Original: Flow cytometry#showed#surface expression of CD2/ CD3/ CD7 (dim)/ CD8/ and CD56
#16294
middle Confidence
Subject:
histologic_grade
(Histological grading)
→
is_determined_by
→
Object:
fine-needle_aspiration_of_breast
(Diagnostic techniques)
Original: histologic grade#is determined by#fine-needle aspiration of the breast
#16285
middle Confidence
Subject:
tumor
(Tumor cell population)
→
shows
→
Object:
large_nucleoli
(Nucleolus)
Original: tumor#shows#nuclear pleomorphism/ tumor cell spindling/ vesicular nuclei with large nucleoli
#16284
middle Confidence
Subject:
tumor
(Tumor cell population)
→
shows
→
Object:
vesicular_nuclei
(Nuclear structure)
Original: tumor#shows#nuclear pleomorphism/ tumor cell spindling/ vesicular nuclei with large nucleoli
#16283
middle Confidence
Subject:
tumor
(Tumor cell population)
→
shows
→
Object:
tumor_cell_spindling
(Cell morphological characteristics)
Original: tumor#shows#nuclear pleomorphism/ tumor cell spindling/ vesicular nuclei with large nucleoli
#16282
middle Confidence
Subject:
tumor
(Tumor cell population)
→
shows
→
Object:
nuclear_pleomorphism
(Changes in nuclear morphology)
Original: tumor#shows#nuclear pleomorphism/ tumor cell spindling/ vesicular nuclei with large nucleoli
#16260
middle Confidence
Subject:
epithelial_component_of_lesions
(Tissue composition)
→
positive_for
→
Object:
racemase
(Enzymes)
Original: Epithelial component of lesions#is positive for#pancytokeratin (AE1/3) and racemase
#16259
middle Confidence
Subject:
epithelial_component_of_lesions
(Tissue composition)
→
positive_for
→
Object:
pancytokeratin_(AE1/3)
(Protein markers)
Original: Epithelial component of lesions#is positive for#pancytokeratin (AE1/3) and racemase
#16190
middle Confidence
Subject:
FISH analysis
(Molecular detection technology)
→
shows
→
Object:
NTRK2_gene_break-apart
(Abnormal gene structure)
Original: FISH analysis#shows#NTRK1 gene break-apart in 1 case and NTRK2 gene break-apart in 2 cases
#16189
middle Confidence
Subject:
FISH analysis
(Molecular detection technology)
→
shows
→
Object:
NTRK1_gene_break-apart
(Abnormal gene structure)
Original: FISH analysis#shows#NTRK1 gene break-apart in 1 case and NTRK2 gene break-apart in 2 cases
#16155
middle Confidence
Subject:
polygonal_cells_with_eosinophilic_cytoplasm_distinct_cell_borders_round_vesicular_nuclei_and_prominent_nucleoli
(Cell morphology)
→
present_in
→
Object:
gallbladder_tumor
(Disease Entity)
Original: Tumor#contains#polygonal cells with eosinophilic cytoplasm/ distinct cell borders/ round vesicular nuclei/ and prominent nucleoli
#16154
middle Confidence
Subject:
discohesive_cells_with_vacuolated_cytoplasm_and_prominent_nucleoli
(Cell morphology)
→
included_in
→
Object:
cytomorphologic_characteristics
(Cell morphological characteristics)
Original: Cytomorphologic characteristics#included#discohesive cells with vacuolated cytoplasm and prominent nucleoli
#16089
middle Confidence
Subject:
anti-RPI_antibody
(Antibody)
→
visualize
→
Object:
chromosomal_distribution_of_NORs
(chromosomal region)
Original: anti-RPI antibody#visualizes#chromosomal distribution of NORs in mammalian species and human tumor cells
#16051
middle Confidence
Subject:
tumor
(Tumor tissue)
→
shows
→
Object:
proliferation_of_medium_to_large_monomorphic_lymphocytes
(Cell proliferation phenomenon)
Original: tumor#shows#a proliferation of medium- to large-sized monomorphic lymphocytes
#16005
middle Confidence
Subject:
prominent_nucleoli
(Cellular substructure)
→
are_assessed_as_parameter_in
→
Object:
SCLC_cases
(disease)
Original: Prominent nucleoli#are assessed as a parameter in#LCNEC and SCLC cases
#16004
middle Confidence
Subject:
prominent_nucleoli
(Cellular substructure)
→
are_assessed_as_parameter_in
→
Object:
LCNEC_cases
(disease)
Original: Prominent nucleoli#are assessed as a parameter in#LCNEC and SCLC cases
#16003
middle Confidence
Subject:
imprint_smears
(Pathological technology)
→
are_reviewed_for
→
Object:
SCLC_cases
(disease)
Original: Aspiration cytologic and imprint smears#are reviewed for#LCNEC and SCLC cases
#16002
middle Confidence
Subject:
imprint_smears
(Pathological technology)
→
are_reviewed_for
→
Object:
LCNEC_cases
(disease)
Original: Aspiration cytologic and imprint smears#are reviewed for#LCNEC and SCLC cases
#16001
middle Confidence
Subject:
aspiration_cytologic_smears
(Pathological technology)
→
are_reviewed_for
→
Object:
SCLC_cases
(disease)
Original: Aspiration cytologic and imprint smears#are reviewed for#LCNEC and SCLC cases
#16000
middle Confidence
Subject:
aspiration_cytologic_smears
(Pathological technology)
→
are_reviewed_for
→
Object:
LCNEC_cases
(disease)
Original: Aspiration cytologic and imprint smears#are reviewed for#LCNEC and SCLC cases
#15995
middle Confidence
Subject:
nucleoli_perimeter
(Cellular substructure parameters)
→
shows_greatest_difference_between
→
Object:
cancerous_pancreas
(Diseased tissue)
Original: Nucleoli area and perimeter#show#greatest differences between cancerous and normal pancreas
#15994
middle Confidence
Subject:
nucleoli_area
(Cellular substructure parameters)
→
shows_greatest_difference_between
→
Object:
cancerous_pancreas
(Diseased tissue)
Original: Nucleoli area and perimeter#show#greatest differences between cancerous and normal pancreas
#15993
middle Confidence
Subject:
digital_cell_image_analysis
(Digital health tools)
→
is_carried_out_on
→
Object:
haematoxylin_and_eosin_stained_slides
(Pathological sections)
Original: Digital cell image analysis#is carried out on#haematoxylin and eosin-stained slides of cancer patients
#15992
middle Confidence
Subject:
measurement_of_cytological_parameters
(Cell morphology measurements)
→
is_applied_in
→
Object:
adenocarcinoma_of_the_pancreas
(disease)
Original: Interactive image analysis system#is applied to#measure cytological parameters of adenocarcinoma of the pancreas
#15986
middle Confidence
Subject:
Atypical_epithelioid_trophoblastic_lesion
(Histopathological entities)
→
has
→
Object:
unique_histological_features
(Histological characteristics)
Original: Atypical epithelioid trophoblastic lesion#has#unique histological features
#15953
middle Confidence
Subject:
Ph-F
(Fluorescent probes)
→
becomes_reactive_with
→
Object:
apoptotic_cells
(Apoptosis)
Original: cells#become reactive with#Ph-F during apoptosis triggered by TPT or H2O2
#15929
middle Confidence
Subject:
Ag-NORs
(Molecular markers)
→
are_studied_in
→
Object:
non-Hodgkin's_lymphomas
(disease)
Original: Ag-NORs#are studied in#non-Hodgkin's lymphomas/ palatine tonsils/ and reactive lymph nodes
#15924
middle Confidence
Subject:
mean_AgNOR_count
(Average AgNOR count)
→
is_lower_in
→
Object:
normal_endocervical_cell
(Normal cervical cells)
Original: Mean AgNOR counts#are higher in#AIS and invasive adenocarcinoma compared to normal endocervical cells
#15923
middle Confidence
Subject:
mean_AgNOR_count
(Average AgNOR count)
→
is_higher_in
→
Object:
invasive_adenocarcinoma
(Invasive adenocarcinoma)
Original: Mean AgNOR counts#are higher in#AIS and invasive adenocarcinoma compared to normal endocervical cells
#15922
middle Confidence
Subject:
mean_AgNOR_count
(Average AgNOR count)
→
is_higher_in
→
Object:
AIS
(Intraepithelial adenocarcinoma)
Original: Mean AgNOR counts#are higher in#AIS and invasive adenocarcinoma compared to normal endocervical cells
#15921
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
is_lower_in
→
Object:
fibrocystic_change
(Benign breast disease)
Original: AgNOR counts#are higher in#malignant lesions compared to fibroadenomas or fibrocystic changes
#15920
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
is_lower_in
→
Object:
fibroadenoma
(Benign breast tumors)
Original: AgNOR counts#are higher in#malignant lesions compared to fibroadenomas or fibrocystic changes
#15919
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
is_higher_in
→
Object:
malignant_lesion
(Malignant tumors)
Original: AgNOR counts#are higher in#malignant lesions compared to fibroadenomas or fibrocystic changes
#15916
middle Confidence
Subject:
Pleural_effusions
(Pleural effusion)
→
are_studied_in
→
Object:
Benign_disease
(Benign diseases)
Original: Pleural effusions#are studied in#malignant and benign diseases using silver staining
#15915
middle Confidence
Subject:
Pleural_effusions
(Pleural effusion)
→
are_studied_in
→
Object:
Malignant_disease
(Tumor diseases)
Original: Pleural effusions#are studied in#malignant and benign diseases using silver staining
#15914
middle Confidence
Subject:
Bone_marrow_cells
(Bone marrow cells)
→
are_studied_in
→
Object:
AML
(Tumor diseases)
Original: Peripheral blood and bone marrow cells#are studied in#patients with T-ALL/ B-precursor ALL/ and AML
#15913
middle Confidence
Subject:
Bone_marrow_cells
(Bone marrow cells)
→
are_studied_in
→
Object:
B-precursor_ALL
(Tumor diseases)
Original: Peripheral blood and bone marrow cells#are studied in#patients with T-ALL/ B-precursor ALL/ and AML
#15912
middle Confidence
Subject:
Bone_marrow_cells
(Bone marrow cells)
→
are_studied_in
→
Object:
T-ALL
(Tumor diseases)
Original: Peripheral blood and bone marrow cells#are studied in#patients with T-ALL/ B-precursor ALL/ and AML
#15911
middle Confidence
Subject:
Peripheral_blood_cells
(Peripheral blood cells)
→
are_studied_in
→
Object:
AML
(Tumor diseases)
Original: Peripheral blood and bone marrow cells#are studied in#patients with T-ALL/ B-precursor ALL/ and AML
#15910
middle Confidence
Subject:
Peripheral_blood_cells
(Peripheral blood cells)
→
are_studied_in
→
Object:
B-precursor_ALL
(Tumor diseases)
Original: Peripheral blood and bone marrow cells#are studied in#patients with T-ALL/ B-precursor ALL/ and AML
#15909
middle Confidence
Subject:
Peripheral_blood_cells
(Peripheral blood cells)
→
are_studied_in
→
Object:
T-ALL
(Tumor diseases)
Original: Peripheral blood and bone marrow cells#are studied in#patients with T-ALL/ B-precursor ALL/ and AML
#15908
middle Confidence
Subject:
NORs
(Nucleolar organizing region)
→
is_studied_in
→
Object:
Papanicolaou_preparations_of_cervical_smears
(Cytology slide preparation)
Original: Distribution of NORs#is studied in#Papanicolaou preparations of cervical smears
#15900
middle Confidence
Subject:
AgNOR_protein_values
(Protein expression)
→
correlate_between
→
Object:
cytological_smears
(Cytology samples)
Original: AgNOR protein values#correlate between#histological sections and cytological smears
#15899
middle Confidence
Subject:
AgNOR_protein_values
(Protein expression)
→
correlate_between
→
Object:
histological_sections
(Histological samples)
Original: AgNOR protein values#correlate between#histological sections and cytological smears
#15897
middle Confidence
Subject:
AgNOR_proteins
(Nuclear Organism Markers)
→
correlate_with
→
Object:
nuclear_grade
(Nuclear grade)
Original: AgNOR proteins#correlate with#nuclear grade and prognostic value in endometrial adenocarcinomas
#15894
middle Confidence
Subject:
AgNOR_count
(Nuclear Organism Markers)
→
helps_in
→
Object:
malignant_mesothelial_cells
(Mesothelial cells)
Original: AgNOR count#helps in#distinguishing benign from malignant mesothelial cells in pleural fluids
#15893
middle Confidence
Subject:
AgNOR_count
(Nuclear Organism Markers)
→
helps_in
→
Object:
benign_mesothelial_cells
(Mesothelial cells)
Original: AgNOR count#helps in#distinguishing benign from malignant mesothelial cells in pleural fluids
#15889
middle Confidence
Subject:
AgNOR_calculation
(AgNOR Count)
→
distinguishes
→
Object:
NHL_high_grade
(High-grade non-Hodgkin lymphoma)
Original: Ag-NOR calculation#distinguishes#NHL of low grade from high grade based on Ag-grains per nucleus
#15888
middle Confidence
Subject:
AgNOR_calculation
(AgNOR Count)
→
distinguishes
→
Object:
NHL_low_grade
(Low-grade non-Hodgkin lymphoma)
Original: Ag-NOR calculation#distinguishes#NHL of low grade from high grade based on Ag-grains per nucleus
#15887
middle Confidence
Subject:
Non_Hodgkins_lymphoma
(Non-Hodgkin's lymphoma)
→
are_evaluated_with
→
Object:
AgNOR
(Nucleolar organizer region)
Original: NHL of low and high grades#are evaluated with#Ag-NOR and mitotic regimen
#15885
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
increase_to
→
Object:
CIN_III
(Cervical intraepithelial neoplasia grade III)
Original: Mean numbers of AgNORs#increase from#CIN I to CIN III
#15884
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
increase_from
→
Object:
CIN_I
(Cervical intraepithelial neoplasia grade I)
Original: Mean numbers of AgNORs#increase from#CIN I to CIN III
#15870
middle Confidence
Subject:
malignant_epithelial_odontogenic_tumor
(Malignant epithelial odontogenic tumor)
→
exhibits
→
Object:
mitotic_activity
(Mitotic activity)
Original: Malignant epithelial odontogenic tumor#exhibits#cytologic features of malignancy/ like atypia and mitotic activity
#15869
middle Confidence
Subject:
malignant_epithelial_odontogenic_tumor
(Malignant epithelial odontogenic tumor)
→
exhibits
→
Object:
atypia
(Cellular atypia)
Original: Malignant epithelial odontogenic tumor#exhibits#cytologic features of malignancy/ like atypia and mitotic activity
#15862
middle Confidence
Subject:
AgNOR_score
(Nucleolar organizer region-related silver staining fraction)
→
is_downregulated_in
→
Object:
adenoma
(Adenoma)
Original: AgNOR scores in carcinomas#were found to be higher than#adenomas
#15861
middle Confidence
Subject:
AgNOR_score
(Nucleolar organizer region-related silver staining fraction)
→
is_upregulated_in
→
Object:
carcinoma
(Malignant tumors)
Original: AgNOR scores in carcinomas#were found to be higher than#adenomas
#15857
middle Confidence
Subject:
p53_positivity
(Tumor suppressor protein positive)
→
is_found_in
→
Object:
cells_in_intraepithelial_spread
(Abnormal cells)
Original: EMA and p53 positivity#is found in#cells in intraepithelial spread
#15856
middle Confidence
Subject:
EMA_positivity
(Epithelial membrane antigen positive)
→
is_found_in
→
Object:
cells_in_intraepithelial_spread
(Abnormal cells)
Original: EMA and p53 positivity#is found in#cells in intraepithelial spread
#15855
middle Confidence
Subject:
Ki-67
(Cell proliferation antigen)
→
demonstrates
→
Object:
nuclear_positivity
(Molecular test results)
Original: EMA/ p53/ Ki-67#demonstrate#positivity in nuclei
#15854
middle Confidence
Subject:
p53
(Tumor suppressor proteins)
→
demonstrates
→
Object:
nuclear_positivity
(Molecular test results)
Original: EMA/ p53/ Ki-67#demonstrate#positivity in nuclei
#15853
middle Confidence
Subject:
EMA
(Epithelial membrane antigen)
→
demonstrates
→
Object:
nuclear_positivity
(Molecular test results)
Original: EMA/ p53/ Ki-67#demonstrate#positivity in nuclei
#15816
middle Confidence
Subject:
mean_AgNOR_per_nucleus
(Molecular detection indicators)
→
is_found_in
→
Object:
NPC
(Tumor tissue)
Original: Mean value of Ag-NOR per nucleus#was found in#NPC/ chronic nasopharyngitis/ and benign hyperplasia of mucosal epithelial
#15814
middle Confidence
Subject:
silver_staining_particle_count
(Molecular detection indicators)
→
has_limited_value_in
→
Object:
grading_bladder_tumors
(Tumor grade assessment)
Original: Counting of silver staining particles#is of limited value in#grading bladder tumors
#15813
middle Confidence
Subject:
Argyrophilic proteins of NORs
(Molecular markers)
→
are_studied_in
→
Object:
bladder_tumors
(Tumor tissue)
Original: Argyrophilic proteins of NORs#were studied in#bladder tumors
#15812
middle Confidence
Subject:
AgNOR_technique
(Molecular detection technology)
→
is_applied_to
→
Object:
colorectal_epithelial_neoplasia_lesions
(Tumor tissue)
Original: AgNOR technique#was applied to#colorectal epithelial neoplasia lesions
#15811
middle Confidence
Subject:
Nuclear_p53_accumulation
(Protein expression phenotype)
→
is_upregulated_in
→
Object:
salivary_gland_tumors
(Tumor tissue)
Original: Nuclear p53 accumulation#was observed in#15 tumors/ 10 of which showed DNA aneuploidy
#15780
middle Confidence
Subject:
AgNOR_score
(Molecular pathology indicators)
→
is_indicator_of
→
Object:
tumor_size
(Tumor phenotype)
Original: AgNOR score#is an indicator of#tumor size
#15779
middle Confidence
Subject:
TNM_staging
(Clinical staging)
→
correlated_to
→
Object:
AgNOR_score
(Nucleus-associated molecules)
Original: TNM staging#was correlated to#AgNOR score
#15778
middle Confidence
Subject:
AgNOR_score
(Nucleus-associated molecules)
→
related_to
→
Object:
estrogen_receptor_status
(Receptor status)
Original: AgNOR score#was related to#clinical staging and estrogen receptor status in breast carcinoma
#15777
middle Confidence
Subject:
AgNOR_score
(Nucleus-associated molecules)
→
related_to
→
Object:
clinical_staging
(Clinical staging)
Original: AgNOR score#was related to#clinical staging and estrogen receptor status in breast carcinoma
#15772
middle Confidence
Subject:
AgNOR_count
(AgNOR Count)
→
distinguishes
→
Object:
R-phase_of_CTVT
(CTVT cell R phase)
Original: AgNOR count#distinguishes#P-and R-phases of CTVT
#15771
middle Confidence
Subject:
AgNOR_count
(AgNOR Count)
→
distinguishes
→
Object:
P-phase_of_CTVT
(CTVT cell P phase)
Original: AgNOR count#distinguishes#P-and R-phases of CTVT
#15770
middle Confidence
Subject:
silver-stained_nucleolar_organizer_regions
(Silver-stained nucleolar organizer region)
→
are_studied_in
→
Object:
patients_with_non-invasive_papillary_bladder_tumor
(Patients with bladder papilloma)
Original: silver-stained nucleolar organizer regions (AgNORs)#are studied in#patients with non-invasive papillary bladder tumor
#15769
middle Confidence
Subject:
glandular_basal_cells_staining
(Glandular basal cell staining)
→
is_performed_on
→
Object:
prostate_biopsy_tissue
(Prostate biopsy)
Original: combined histochemical-immunohistochemical staining for AgNORs and glandular basal cells#is performed on#prostate biopsy tissue
#15768
middle Confidence
Subject:
AgNORs_staining
(AgNORs staining)
→
is_performed_on
→
Object:
prostate_biopsy_tissue
(Prostate biopsy)
Original: combined histochemical-immunohistochemical staining for AgNORs and glandular basal cells#is performed on#prostate biopsy tissue
#15767
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
are_identified_by
→
Object:
micro-imaging_analyzer
(Imaging Analyzer)
Original: nucleolar organizer regions (NORs)#are identified by#silver-staining and micro-imaging analyzer techniques in vaginal aspirate-smears
#15766
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
are_identified_by
→
Object:
silver-staining
(Dyeing technology)
Original: nucleolar organizer regions (NORs)#are identified by#silver-staining and micro-imaging analyzer techniques in vaginal aspirate-smears
#15757
middle Confidence
Subject:
AgNOR_morphometric_analysis
(Morphological analysis techniques)
→
assessed_in
→
Object:
malignant_breast_lesions
(Malignant breast lesions)
Original: Diagnostic value of AgNOR morphometric analysis#was assessed in#benign and malignant breast lesions
#15756
middle Confidence
Subject:
AgNOR_morphometric_analysis
(Morphological analysis techniques)
→
assessed_in
→
Object:
benign_breast_lesions
(Benign breast lesions)
Original: Diagnostic value of AgNOR morphometric analysis#was assessed in#benign and malignant breast lesions
#15753
middle Confidence
Subject:
AgNOR_staining
(Molecular marker detection)
→
identified
→
Object:
ITGCN
(Germ cell tumor in situ)
Original: PLAP and AgNOR staining#identified#ITGCN in 84% of cases adjacent to invasive tumors
#15752
middle Confidence
Subject:
PLAP_staining
(Molecular marker detection)
→
identified
→
Object:
ITGCN
(Germ cell tumor in situ)
Original: PLAP and AgNOR staining#identified#ITGCN in 84% of cases adjacent to invasive tumors
#15709
middle Confidence
Subject:
AgNOR
(Nucleolar organizer region-associated protein)
→
was_measured_in
→
Object:
malignant_urothelial_cells
(Tumor cells)
Original: Argyrophilic NOR (AgNOR)#was measured in#benign and malignant urothelial cells in human urinary bladder
#15708
middle Confidence
Subject:
AgNOR
(Nucleolar organizer region-associated protein)
→
was_measured_in
→
Object:
urothelial_cells
(Epithelial cells)
Original: Argyrophilic NOR (AgNOR)#was measured in#benign and malignant urothelial cells in human urinary bladder
#15692
middle Confidence
Subject:
nucleolus_organizer_regions
(Molecular markers)
→
is_associated_with
→
Object:
increased_tumor_differentiation
(Tumor differentiation ability)
Original: Greater number of nucleolus organizer regions#was associated with#increased tumor differentiation
#15691
middle Confidence
Subject:
growth_fraction_of_nucleolus_organizer_regions
(Molecular markers)
→
is_higher_in
→
Object:
undifferentiated_carcinomas
(Tumor grade)
Original: Higher growth fraction of nucleolus organizer regions#was noted in#undifferentiated carcinomas
#15689
middle Confidence
Subject:
DNA_analysis
(Molecular detection methods)
→
correlates_with
→
Object:
histologic_tumor_type
(Disease phenotype)
Original: DNA analysis#correlated with#histologic tumor type
#15681
middle Confidence
Subject:
Nucleolar_organizer_regions_per_cell
(Nuclear structure index)
→
correlates_with
→
Object:
histological_grading_techniques
(Pathological grading method)
Original: Nucleolar organizer regions per cell#correlate with#histological grading techniques for neoplasms
#15651
middle Confidence
Subject:
DNA_ploidy_estimation
(Molecular analysis methods)
→
evaluated_in
→
Object:
FNA_from_Wilms_tumor
(Disease samples)
Original: Cytomorphologic features and DNA ploidy estimation#were evaluated in#FNAs from Wilms' tumors
#15650
middle Confidence
Subject:
Cytomorphologic_features
(Cell morphological characteristics)
→
evaluated_in
→
Object:
FNA_from_Wilms_tumor
(Disease samples)
Original: Cytomorphologic features and DNA ploidy estimation#were evaluated in#FNAs from Wilms' tumors
#15647
middle Confidence
Subject:
Pap_test
(Cytological testing methods)
→
assessed_for
→
Object:
background_features
(Cell morphology)
Original: Pap tests#were assessed for#architectural/ cellular/ and background features
#15646
middle Confidence
Subject:
Pap_test
(Cytological testing methods)
→
assessed_for
→
Object:
cellular_features
(Cell morphology)
Original: Pap tests#were assessed for#architectural/ cellular/ and background features
#15645
middle Confidence
Subject:
Pap_test
(Cytological testing methods)
→
assessed_for
→
Object:
architectural_features
(Cell morphology)
Original: Pap tests#were assessed for#architectural/ cellular/ and background features
#15640
middle Confidence
Subject:
BNLs_with_hyperbasophilic_lymphocytes
(B cells)
→
is_predictive_of
→
Object:
diagnosis_of_PPBL
(Disease diagnosis)
Original: BNLs with monocytoid and/or hyperbasophilic lymphocytes#is predictive of#diagnosis of PPBL
#15639
middle Confidence
Subject:
BNLs_with_monocytoid_lymphocytes
(B cells)
→
is_predictive_of
→
Object:
diagnosis_of_PPBL
(Disease diagnosis)
Original: BNLs with monocytoid and/or hyperbasophilic lymphocytes#is predictive of#diagnosis of PPBL
#15620
middle Confidence
Subject:
Lesion
(Pathological morphological entity)
→
appeared_as
→
Object:
extraparenchymal_hemorrhage_on_MRI
(Imaging phenotype)
Original: Lesion#appeared as#extraparenchymal hemorrhage on MRI
#15611
middle Confidence
Subject:
inguinal_lymphadenopathy
(Clinical manifestations)
→
was_suspicious_for
→
Object:
metastatic_disease
(disease)
Original: Left inguinal lymphadenopathy#was suspicious for#metastatic disease by ultrasound examination
#15610
middle Confidence
Subject:
tissue_diagnosis
(Histological diagnosis)
→
was_obtained_in
→
Object:
case
(Case)
Original: Tissue diagnosis#was obtained in#173 cases
#15586
middle Confidence
Subject:
cytologic_features_of_individual_cells
(Cytological characteristics)
→
may_distinguish
→
Object:
NC-DCIS
(Tumor diseases)
Original: DCIS#is#morphologically diverse and cytologic features of individual cells on FNAB may distinguish C-DCIS from NC-DCIS
#15585
middle Confidence
Subject:
cytologic_features_of_individual_cells
(Cytological characteristics)
→
may_distinguish
→
Object:
C-DCIS
(Tumor diseases)
Original: DCIS#is#morphologically diverse and cytologic features of individual cells on FNAB may distinguish C-DCIS from NC-DCIS
#15582
middle Confidence
Subject:
epithelioid_leiomyoma
(Tumor diseases)
→
presents
→
Object:
differential_diagnosis
(Differential Diagnosis)
Original: This article#presents#the pathologic features and differential diagnosis of an example of epithelioid leiomyoma
#15581
middle Confidence
Subject:
epithelioid_leiomyoma
(Tumor diseases)
→
presents
→
Object:
pathologic_features
(Pathological characteristics)
Original: This article#presents#the pathologic features and differential diagnosis of an example of epithelioid leiomyoma
#15567
middle Confidence
Subject:
Pleural_fluid
(Body fluid specimens)
→
contained_predominantly
→
Object:
mesothelial_cells
(Mesothelial cells)
Original: The pleural fluid#contained predominantly#atypical spheroid cell clusters and numerous mesothelial cells
#15566
middle Confidence
Subject:
Pleural_fluid
(Body fluid specimens)
→
contained_predominantly
→
Object:
atypical_spheroid_cell_clusters
(Cell morphology)
Original: The pleural fluid#contained predominantly#atypical spheroid cell clusters and numerous mesothelial cells
#15564
middle Confidence
Subject:
PI3KCB
(Protein coding genes)
→
may_be_exploited_as
→
Object:
potential_diagnostic_target
(Potential diagnostic targets)
Original: Metabolic pathway-related genes#may be exploited as#potential targets for diagnosis and treatment
#15562
middle Confidence
Subject:
PIK3R5
(Protein coding genes)
→
may_be_exploited_as
→
Object:
potential_diagnostic_target
(Potential diagnostic targets)
Original: Metabolic pathway-related genes#may be exploited as#potential targets for diagnosis and treatment
#15561
middle Confidence
Subject:
aspirate
(Cytology samples)
→
reveals
→
Object:
atypical_cells_with_prominent_nucleoli
(Abnormal cells)
Original: Aspirate#revealed#atypical cells with high nuclear-cytoplasmic ratio/ coarsely granular chromatin/ and prominent nucleoli
#15560
middle Confidence
Subject:
aspirate
(Cytology samples)
→
reveals
→
Object:
atypical_cells_with_coarsely_granular_chromatin
(Abnormal cells)
Original: Aspirate#revealed#atypical cells with high nuclear-cytoplasmic ratio/ coarsely granular chromatin/ and prominent nucleoli
#15559
middle Confidence
Subject:
aspirate
(Cytology samples)
→
reveals
→
Object:
atypical_cells_with_high_nuclear_cytoplasmic_ratio
(Abnormal cells)
Original: Aspirate#revealed#atypical cells with high nuclear-cytoplasmic ratio/ coarsely granular chromatin/ and prominent nucleoli
#15558
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
shows
→
Object:
variable_expressivity_of_melanocytic_markers
(Molecular marker expression)
Original: Immunohistochemistry#shows#variable expressivity of melanocytic markers
#15557
middle Confidence
Subject:
tumor_nests
(Tumor tissue structure)
→
are_arranged_as
→
Object:
glandular_structures
(Tumor tissue structure)
Original: Histopathological examination#showed#tumor nests near the necrotic foci arranged as angulated tubules/ tubulopapillary/ and glandular structures
#15556
middle Confidence
Subject:
tumor_nests
(Tumor tissue structure)
→
are_arranged_as
→
Object:
tubulopapillary_structures
(Tumor tissue structure)
Original: Histopathological examination#showed#tumor nests near the necrotic foci arranged as angulated tubules/ tubulopapillary/ and glandular structures
#15555
middle Confidence
Subject:
tumor_nests
(Tumor tissue structure)
→
are_arranged_as
→
Object:
angulated_tubules
(Tumor tissue structure)
Original: Histopathological examination#showed#tumor nests near the necrotic foci arranged as angulated tubules/ tubulopapillary/ and glandular structures
#15550
middle Confidence
Subject:
systematic_review
(Research Methods)
→
describes
→
Object:
clinicopathologic_features_of_PGM
(Disease phenotype)
Original: A systematic review#describes#clinicopathologic features of PGM
#15547
middle Confidence
Subject:
CD43
(Cell surface molecules)
→
serves_as
→
Object:
diagnostic_marker_for_SCLC
(Diagnostic markers)
Original: This report#highlights#a potential diagnostic pitfall in the diagnosis of SCLC/ urges caution in cases of LCA and CD43 positivity
#15507
middle Confidence
Subject:
CBC_findings
(Blood routine test results)
→
include
→
Object:
atypical_mononuclear_cells_on_blood_film
(Cytological abnormalities)
Original: CBC findings#included#mild nonregenerative anemia/ marked thrombocytopenia/ and a few atypical mononuclear cells on the blood film
#15506
middle Confidence
Subject:
CBC_findings
(Blood routine test results)
→
include
→
Object:
marked_thrombocytopenia
(Disease phenotype)
Original: CBC findings#included#mild nonregenerative anemia/ marked thrombocytopenia/ and a few atypical mononuclear cells on the blood film
#15505
middle Confidence
Subject:
CBC_findings
(Blood routine test results)
→
include
→
Object:
mild_nonregenerative_anemia
(Disease phenotype)
Original: CBC findings#included#mild nonregenerative anemia/ marked thrombocytopenia/ and a few atypical mononuclear cells on the blood film
#15504
middle Confidence
Subject:
fine-needle_cytology
(Cytology)
→
diagnoses
→
Object:
eccrine_spiradenoma_of_the_breast
(Tumor phenotype)
Original: Fine-needle cytology#diagnosed#eccrine spiradenoma of the breast
#15496
middle Confidence
Subject:
clinicopathologic_features_of_patients
(Clinicopathological characteristics)
→
were_reviewed_for
→
Object:
supratentorial_oligodendroglioma
(disease)
Original: Clinicopathologic features of patients#were reviewed for#supratentorial oligodendroglioma
#15488
middle Confidence
Subject:
tumor_histopathology
(Histological characteristics)
→
revealed
→
Object:
melanin_granules
(Cell structure characteristics)
Original: Tumor histopathology#revealed#characteristics including tumor cells in nests/ sheets/ cords/ with melanin granules/ heterogeneous nuclei/ and pathological mitosis
#15487
middle Confidence
Subject:
tumor_histopathology
(Histological characteristics)
→
revealed
→
Object:
tumor_cells_in_nests
(Cell structure characteristics)
Original: Tumor histopathology#revealed#characteristics including tumor cells in nests/ sheets/ cords/ with melanin granules/ heterogeneous nuclei/ and pathological mitosis
#15486
middle Confidence
Subject:
tumor_cell_nuclei
(Nucleus)
→
showed
→
Object:
moderate_nuclear_atypia
(Cell morphology)
Original: Tumor cell nuclei#showed#moderate nuclear atypia and pleomorphism with inconspicuous nucleoli
#15485
middle Confidence
Subject:
tumor
(Tumor Entities)
→
shows
→
Object:
hybrid_spindle_cell_and_epithelioid_cytomorphology
(Cell morphology)
Original: Histopathologic examination#revealed#tumor with hybrid spindle cell and epithelioid cytomorphology/ high-grade features/ prominent nucleoli/ and atypical mitosis
#15484
middle Confidence
Subject:
ALK
(Tyrosine kinase)
→
is_positive_in
→
Object:
entity_with_myogenic_markers
(Tumor Entities)
Original: This entity#has#distinctive clinicopathologic features: aggressive clinical course/ craniofacial bone preference/ spindle and epithelioid histomorphology/ positive immunohistochemistry for epithelial markers/ ALK/ and myogenic markers
#15483
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_identified_by
→
Object:
abnormal_morphological_features
(Cell morphology)
Original: Tumor cells#were identifiable by#at least 20 abnormal cells with specific morphological features
#15482
middle Confidence
Subject:
Primary_cutaneous_LELC
(Tumor Entities)
→
shares_histopathologic_features_with
→
Object:
nasopharyngeal_carcinoma
(Tumor Entities)
Original: Primary cutaneous LELC#is#cutaneous neoplasm with histopathologic features identical to undifferentiated subtype of nasopharyngeal carcinoma
#15478
middle Confidence
Subject:
ETV6_NTRK3_fusion
(Gene fusion)
→
is_associated_with
→
Object:
mammary_analog_secretory_carcinoma
(Tumor type)
Original: mammary analog secretory carcinoma (MASC)#arises in#thyroid
#15475
middle Confidence
Subject:
prostatic_adenocarcinoma
(Tumor type)
→
is_associated_with
→
Object:
bilateral_palpable_mammary_masses
(Tumor manifestations)
Original: An 81-year-old man with a history of prostatic adenocarcinoma#presented with#bilateral palpable mammary masses
#15454
middle Confidence
Subject:
Resected_tumor
(Tumor tissue)
→
reveals
→
Object:
Solid_proliferation_of_large_undifferentiated_cells
(Cell proliferation characteristics)
Original: Resected tumor#reveals#nested and solid proliferation of large undifferentiated cells
#15453
middle Confidence
Subject:
Resected_tumor
(Tumor tissue)
→
reveals
→
Object:
Nested_proliferation_of_large_undifferentiated_cells
(Cell proliferation characteristics)
Original: Resected tumor#reveals#nested and solid proliferation of large undifferentiated cells
#15396
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
were_positive_for
→
Object:
epithelial_membrane_antigen
(Protein markers)
Original: Tumor cells#were positive for#epithelial membrane antigen
#15395
middle Confidence
Subject:
Loss_of_FH_staining
(Molecular markers)
→
was_seen_in
→
Object:
2_of_5_cases
(Diagnosis)
Original: Loss of FH staining#was seen in#2 of the 5 cases
#15394
middle Confidence
Subject:
Cytologic_diagnosis_of_SCTATs
(Diagnostic Methods)
→
was_first_reported_by
→
Object:
endoscopic_ultrasound_guided_fine_needle_aspiration
(Diagnostic techniques)
Original: Cytologic diagnosis of SCTATs#was first reported by#endoscopic ultrasound-guided fine needle aspiration
#15360
middle Confidence
Subject:
diagnostic_criterion
(Diagnostic criteria)
→
assessed_by
→
Object:
likelihood_ratio
(Statistical indicators)
Original: The diagnostic power of each criterion#was assessed by#the likelihood ratio (LR)
#15359
middle Confidence
Subject:
AgNOR_staining
(Molecular staining technology)
→
analyzed_in
→
Object:
neoplastic_follicular_lesions_of_thyroid
(Histopathological features)
Original: Argyrophil staining of nucleolar organizer regions (AgNOR)#was studied in#95 nonneoplastic and neoplastic follicular lesions of the thyroid
#15358
middle Confidence
Subject:
AgNOR_staining
(Molecular staining technology)
→
analyzed_in
→
Object:
nonneoplastic_follicular_lesions_of_thyroid
(Histopathological features)
Original: Argyrophil staining of nucleolar organizer regions (AgNOR)#was studied in#95 nonneoplastic and neoplastic follicular lesions of the thyroid
#15357
middle Confidence
Subject:
AgNOR_staining
(Molecular staining technology)
→
analyzed_in
→
Object:
follicular_cell_neoplasms_of_thyroid
(Tumor tissue)
Original: Diagnostic value of AgNOR staining#was studied in#follicular cell neoplasms of the thyroid
#15352
middle Confidence
Subject:
patient_age
(Patient characteristics)
→
is_not_predictive_of
→
Object:
cancer_on_follow_up_biopsy
(Disease phenotype)
Original: Serum prostate-specific antigen/ digital rectal examination result/ and patient age#were not predictive of#cancer on follow-up biopsy
#15351
middle Confidence
Subject:
digital_rectal_examination_result
(Clinical examination)
→
is_not_predictive_of
→
Object:
cancer_on_follow_up_biopsy
(Disease phenotype)
Original: Serum prostate-specific antigen/ digital rectal examination result/ and patient age#were not predictive of#cancer on follow-up biopsy
#15350
middle Confidence
Subject:
serum_prostate_specific_antigen
(Tumor markers)
→
is_not_predictive_of
→
Object:
cancer_on_follow_up_biopsy
(Disease phenotype)
Original: Serum prostate-specific antigen/ digital rectal examination result/ and patient age#were not predictive of#cancer on follow-up biopsy
#15346
middle Confidence
Subject:
cytologic_criteria
(Cytological criteria)
→
includes
→
Object:
irregular_nuclear_borders
(Morphological characteristics)
Original: Cytologic criteria#include#increased nuclear/cytoplasmic ratios and irregular nuclear borders
#15345
middle Confidence
Subject:
cytologic_criteria
(Cytological criteria)
→
includes
→
Object:
increased_nuclear_to_cytoplasmic_ratio
(Morphological characteristics)
Original: Cytologic criteria#include#increased nuclear/cytoplasmic ratios and irregular nuclear borders
#15344
middle Confidence
Subject:
Cytologic_features
(Cytological characteristics)
→
predict
→
Object:
mucoepidermoid_carcinoma
(Mucoepidermoid carcinoma)
Original: Cytologic features#predict#mucoepidermoid carcinoma
#15315
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
express
→
Object:
CD68
(protein)
Original: neoplastic cells#express#S100 and CD68
#15314
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
express
→
Object:
S100
(protein)
Original: neoplastic cells#express#S100 and CD68
#15306
middle Confidence
Subject:
vascular_neoplasm
(Tumor type)
→
included_in
→
Object:
clinical_differential_diagnosis
(Clinical diagnosis)
Original: Clinical differential diagnosis#includes#epithelial and vascular neoplasms
#15305
middle Confidence
Subject:
epithelial_neoplasm
(Tumor type)
→
included_in
→
Object:
clinical_differential_diagnosis
(Clinical diagnosis)
Original: Clinical differential diagnosis#includes#epithelial and vascular neoplasms
#15302
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_negative_for
→
Object:
Iba1
(Protein markers)
Original: Atypical cells#are negative for#CD3/ CD79a/ Iba1
#15301
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_negative_for
→
Object:
CD79a
(Protein markers)
Original: Atypical cells#are negative for#CD3/ CD79a/ Iba1
#15300
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_negative_for
→
Object:
CD3
(Protein markers)
Original: Atypical cells#are negative for#CD3/ CD79a/ Iba1
#15299
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_positive_for
→
Object:
Pax5
(Protein markers)
Original: Atypical cells#are positive for#FeLV/ CD20/ BLA36/ vimentin/ p16/ p53/ Pax5
#15298
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_positive_for
→
Object:
p53
(Protein markers)
Original: Atypical cells#are positive for#FeLV/ CD20/ BLA36/ vimentin/ p16/ p53/ Pax5
#15297
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_positive_for
→
Object:
p16
(Protein markers)
Original: Atypical cells#are positive for#FeLV/ CD20/ BLA36/ vimentin/ p16/ p53/ Pax5
#15296
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_positive_for
→
Object:
vimentin
(Protein markers)
Original: Atypical cells#are positive for#FeLV/ CD20/ BLA36/ vimentin/ p16/ p53/ Pax5
#15295
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_positive_for
→
Object:
BLA36
(Protein markers)
Original: Atypical cells#are positive for#FeLV/ CD20/ BLA36/ vimentin/ p16/ p53/ Pax5
#15294
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_positive_for
→
Object:
CD20
(Protein markers)
Original: Atypical cells#are positive for#FeLV/ CD20/ BLA36/ vimentin/ p16/ p53/ Pax5
#15293
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_positive_for
→
Object:
FeLV
(Virus)
Original: Atypical cells#are positive for#FeLV/ CD20/ BLA36/ vimentin/ p16/ p53/ Pax5
#15289
middle Confidence
Subject:
frozen_section_diagnosis
(Frozen section diagnosis)
→
identifies
→
Object:
signet_ring_cell_adenocarcinoma
(Tumor diseases)
Original: frozen section diagnosis#identifies#gastrointestinal poorly cohesive and signet-ring cell adenocarcinoma
#15288
middle Confidence
Subject:
frozen_section_diagnosis
(Frozen section diagnosis)
→
identifies
→
Object:
gastrointestinal_poorly_cohesive_adenocarcinoma
(Tumor diseases)
Original: frozen section diagnosis#identifies#gastrointestinal poorly cohesive and signet-ring cell adenocarcinoma
#15264
middle Confidence
Subject:
cytological_findings
(Cytology results)
→
are_compared_with
→
Object:
pathological_findings_in_FNA_series
(Pathological results)
Original: cytological findings#are compared with#pathological findings in FNA series
#15263
middle Confidence
Subject:
false-negative_smears
(Cytology samples)
→
are_reviewed_to_reveal
→
Object:
frequent_error_causes
(Diagnose the cause of the error)
Original: false-negative smears#are reviewed to reveal#frequent error causes
#15237
middle Confidence
Subject:
Immunohistochemical_stains
(Detection Methods)
→
play_important_role_in
→
Object:
differentiation_between_lesions
(Pathological diagnosis process)
Original: Immunohistochemical stains#play#an important role in differentiating between lesions
#15236
middle Confidence
Subject:
Carcinomas
(Tumor diseases)
→
were_identified_on
→
Object:
screening_radiographs
(Imaging tests)
Original: Carcinomas#were#frequently identified on screening radiographs
#15234
middle Confidence
Subject:
Molecular_findings
(Molecular test results)
→
presented_in
→
Object:
Cystic_fibrosis_case
(Disease clinical cases)
Original: Molecular findings#presented in#three cases of CF
#15218
middle Confidence
Subject:
papillary-mucinous_carcinoma
(Tumor diseases)
→
originates_in
→
Object:
pancreas
(organ)
Original: Papillary-mucinous carcinoma#originated in#the pancreas based on immunohistochemical findings
#15201
middle Confidence
Subject:
MIC2
(Cell surface proteins)
→
shows_strongly_positive_immunocytochemical_labeling
→
Object:
six_cases
(Case)
Original: six cases#showed#strongly positive immunocytochemical labeling for MIC2
#15199
middle Confidence
Subject:
SDHB
(Mitochondrial enzyme subunits)
→
shows_negative_staining
→
Object:
tumor_cells
(Tumor cells)
Original: Six tumors#showed#negative immunohistochemical staining for SDHA and SDHB
#15198
middle Confidence
Subject:
SDHA
(Mitochondrial enzyme subunits)
→
shows_negative_staining
→
Object:
tumor_cells
(Tumor cells)
Original: Six tumors#showed#negative immunohistochemical staining for SDHA and SDHB
#15191
middle Confidence
Subject:
tumor_cells
(Cell Type)
→
were_stained_positively_for
→
Object:
keratin
(protein)
Original: Tumor cells#were stained positively for#keratin but not for calcitonin or thyroglobulin
#15190
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
mammographic_calcifications
(Imaging findings)
Original: 31 patients#presented with#mammographic calcifications
#15144
middle Confidence
Subject:
Tumor_cells
(Cell Type)
→
are_positive_for
→
Object:
Vimentin
(Intermediate filament protein)
Original: Tumor cells#were immunohistochemically positive for#vimentin
#15115
middle Confidence
Subject:
study
(Research)
→
was_undertaken_to_specify
→
Object:
cytomorphological_criteria_for_PDAC
(Diagnostic criteria)
Original: Study#was undertaken to specify#cytomorphological criteria for PDAC
#15048
middle Confidence
Subject:
tumor
(Tumor)
→
has
→
Object:
cellular_monomorphism
(Cell morphology)
Original: Tumor#has#infiltrative growth/ variable architectural patterns/ neurotropism/ and cellular monomorphism
#15047
middle Confidence
Subject:
tumor
(Tumor)
→
has
→
Object:
Neurotropism
(Biological characteristics)
Original: Tumor#has#infiltrative growth/ variable architectural patterns/ neurotropism/ and cellular monomorphism
#15046
middle Confidence
Subject:
tumor
(Tumor)
→
has
→
Object:
variable_architectural_patterns
(Organizational structure characteristics)
Original: Tumor#has#infiltrative growth/ variable architectural patterns/ neurotropism/ and cellular monomorphism
#15045
middle Confidence
Subject:
tumor
(Tumor)
→
has
→
Object:
infiltrative_growth
(Biological Process)
Original: Tumor#has#infiltrative growth/ variable architectural patterns/ neurotropism/ and cellular monomorphism
#15044
middle Confidence
Subject:
HSTCL
(Tumor)
→
is_main_cause_of
→
Object:
misdiagnosis
(Misdiagnosis)
Original: Acute leukemia or MDS-like appearance#are#main causes of misdiagnosis of HSTCL 纬未 type
#15043
middle Confidence
Subject:
MDS_like_appearance
(Tumor phenotype)
→
is_main_cause_of
→
Object:
misdiagnosis_of_HSTCL
(Misdiagnosis)
Original: Acute leukemia or MDS-like appearance#are#main causes of misdiagnosis of HSTCL 纬未 type
#15042
middle Confidence
Subject:
acute_leukemia_appearance
(Tumor phenotype)
→
is_main_cause_of
→
Object:
misdiagnosis_of_HSTCL
(Misdiagnosis)
Original: Acute leukemia or MDS-like appearance#are#main causes of misdiagnosis of HSTCL 纬未 type
#15041
middle Confidence
Subject:
malignant_lymphocytes_of_HSTCL
(Malignant lymphocytes)
→
show
→
Object:
mature_lymphocytic_neoplasm_morphology
(Cell morphology)
Original: Malignant cells of HSTCL 纬未 type#have#distinct morphological features of mature lymphocytic neoplasm
#15040
middle Confidence
Subject:
tumor
(Tumor)
→
consists_of
→
Object:
bland_spindle_cells_with_oval_nuclei_and_small_prominent_nucleoli
(Cell morphology)
Original: Majority of tumors#consisted of#bland spindle cells with oval nuclei and small prominent nucleoli
#15039
middle Confidence
Subject:
tumor_cell_ultrastructure
(Cell ultrastructure)
→
shows
→
Object:
irregular_intercellular_lumina_with_microvilli
(Cell morphology)
Original: Ultrastructure of tumor cells#showed#irregular intercellular lumina with some microvilli
#15038
middle Confidence
Subject:
Cytokeratin_14
(protein)
→
is_negative_in
→
Object:
Carcinoma
(Neoplastic diseases)
Original: Cytokeratin 14#was#negative
#15037
middle Confidence
Subject:
Carcinoma
(Neoplastic diseases)
→
shows_positive_for
→
Object:
S100_protein
(protein)
Original: Immunohistological positivity of carcinoma#concerned#S-100 protein/ slightly CEA/ focally cytokeratin 7 and 18
#15032
middle Confidence
Subject:
Cytological_findings
(Cytology results)
→
were_discordant_with
→
Object:
immunohistochemical_results
(Immunohistochemistry results)
Original: Cytological findings#were discordant with#immunohistochemical results in two cases
#15031
middle Confidence
Subject:
Case
(Case)
→
was_misdiagnosed_as
→
Object:
Small-cell_lung_carcinoma
(Neoplastic diseases)
Original: Remaining two cases#were misdiagnosed as#small-cell lung carcinoma
#14986
middle Confidence
Subject:
4-stain_immunopanel
(Immunohistochemistry)
→
subclassifies
→
Object:
pulmonary_large_cell_carcinoma
(disease)
Original: A 4-stain immunopanel#was used to subclassify#pulmonary large cell carcinomas
#14982
middle Confidence
Subject:
bare_nuclei
(Cell morphology)
→
is_prominent_in
→
Object:
UPSC
(Disease subtype)
Original: Anisonucleosis#and#bare nuclei were prominent
#14981
middle Confidence
Subject:
anisonucleosis
(Nuclear abnormalities)
→
is_prominent_in
→
Object:
UPSC
(Disease subtype)
Original: Anisonucleosis#and#bare nuclei were prominent
#14921
middle Confidence
Subject:
Tumor
(Tumor Entities)
→
is_diagnosed_as
→
Object:
vasotropic_and_vasoinvasive_nonepitheliotropic_lymphoma
(Tumor diseases)
Original: Tumor#is diagnosed as#vasotropic and vasoinvasive nonepitheliotropic lymphoma
#14919
middle Confidence
Subject:
Cytomorphologic_features
(Cell morphology)
→
are_observed_in
→
Object:
fine-needle_aspiration_of_metastatic_and_recurrent_melanoma
(Cytology test samples)
Original: Cytomorphologic features#are observed in#fine-needle aspiration of metastatic and recurrent melanoma
#14912
middle Confidence
Subject:
adenocarcinoma
(Tumor type)
→
shows
→
Object:
prominent_central_nucleoli
(Cell morphology)
Original: adenocarcinomas diagnosed as benign#showed#occasional malignant cell with thickened nuclear borders and prominent central nucleoli
#14911
middle Confidence
Subject:
adenocarcinoma
(Tumor type)
→
shows
→
Object:
thickened_nuclear_borders
(Cell morphology)
Original: adenocarcinomas diagnosed as benign#showed#occasional malignant cell with thickened nuclear borders and prominent central nucleoli
#14910
middle Confidence
Subject:
invasive_carcinoma
(Tumor type)
→
has_associated
→
Object:
in_situ_component
(Tumor pathological components)
Original: invasive carcinomas in women younger than 35#have#an associated in situ component
#14909
middle Confidence
Subject:
TBrC
(Tumor subtype)
→
has_characteristic
→
Object:
syncytial_growth_pattern
(Organizing student leaders)
Original: TNBrCa#have characteristic histologic features including#higher tumor grade/ pushing tumor border/ geographic necrosis/ syncytial growth pattern
#14908
middle Confidence
Subject:
TBrC
(Tumor subtype)
→
has_characteristic
→
Object:
geographic_necrosis
(Tissue necrosis)
Original: TNBrCa#have characteristic histologic features including#higher tumor grade/ pushing tumor border/ geographic necrosis/ syncytial growth pattern
#14907
middle Confidence
Subject:
TBrC
(Tumor subtype)
→
has_characteristic
→
Object:
pushing_tumor_border
(Histological characteristics)
Original: TNBrCa#have characteristic histologic features including#higher tumor grade/ pushing tumor border/ geographic necrosis/ syncytial growth pattern
#14893
middle Confidence
Subject:
nuclear_hyperchromatism
(Nuclear phenotype)
→
is_associated_with
→
Object:
malignancy
(Tumor phenotype)
Original: nuclear hyperchromatism#is associated with#malignancy
#14888
middle Confidence
Subject:
Primary_plasma_cell_leukemia
(disease)
→
was_analyzed_using
→
Object:
laboratory_characteristics
(Laboratory characteristics)
Original: Case of primary plasma cell leukemia#was analyzed using#clinical and laboratory characteristics
#14887
middle Confidence
Subject:
Primary_plasma_cell_leukemia
(disease)
→
was_analyzed_using
→
Object:
clinical_characteristics
(Clinical characteristics)
Original: Case of primary plasma cell leukemia#was analyzed using#clinical and laboratory characteristics
#14879
middle Confidence
Subject:
findings
(Diagnosis conclusion)
→
indicate
→
Object:
plasmacytoma
(Tumor type)
Original: Findings#indicated#plasmacytoma
#14875
middle Confidence
Subject:
CK5
(Cytokeratin)
→
is_expressed_in
→
Object:
HGPIN
(Prostate pathology)
Original: Clusters of atypical cells meeting criteria for HGPIN#still expressed#CK5 and were adjacent to focal chronic inflammation
#14869
middle Confidence
Subject:
Laparotomy
(Diagnostic techniques)
→
reveals
→
Object:
adrenal_mass_with_intact_capsule
(Tumor morphology)
Original: Laparotomy#revealed#a lobulated left adrenal mass with intact capsule
#14846
middle Confidence
Subject:
amyloid
(protein)
→
is_positive_for
→
Object:
Congo_red_staining
(Staining characteristics)
Original: Amyloid#was positive for#Congo red staining in three cases
#14845
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
display
→
Object:
prominent_nucleoli
(Nucleolar characteristics)
Original: The neoplastic cells#had#moderate to marked nuclear pleomorphism and prominent nucleoli
#14844
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
display
→
Object:
nuclear_pleomorphism
(Nuclear morphology)
Original: The neoplastic cells#had#moderate to marked nuclear pleomorphism and prominent nucleoli
#14826
middle Confidence
Subject:
Malignant mixed Müllerian tumor
(Tumor type)
→
is_characterized_by
→
Object:
mesenchymal component
(Mesenchymal components)
Original: Malignant mixed Müllerian tumor (MMMT)#is characterized by#a mixture of epithelial and mesenchymal components
#14825
middle Confidence
Subject:
Malignant mixed Müllerian tumor
(Tumor type)
→
is_characterized_by
→
Object:
epithelial component
(Epithelial component)
Original: Malignant mixed Müllerian tumor (MMMT)#is characterized by#a mixture of epithelial and mesenchymal components
#14809
middle Confidence
Subject:
physical_examination
(Clinical examination)
→
revealed
→
Object:
polypoid_reddish_mass_in_mandibular_gingiva
(Clinical manifestations)
Original: physical examination#revealed#a polypoid reddish mass measuring 1.5 × 1.5 × 1 cm in the mandibular gingiva posterior to the front tooth
#14805
middle Confidence
Subject:
lesional_cells
(Tumor-associated cells)
→
are_negative_for
→
Object:
anaplastic_lymphoma_kinase_1
(Receptor tyrosine kinases)
Original: lesional cells#are negative for#CD21/ smooth muscle actin/ ckit/ cytokeratins/ and anaplastic lymphoma kinase 1
#14804
middle Confidence
Subject:
lesional_cells
(Tumor-associated cells)
→
are_negative_for
→
Object:
cytokeratins
(Cytoskeletal proteins)
Original: lesional cells#are negative for#CD21/ smooth muscle actin/ ckit/ cytokeratins/ and anaplastic lymphoma kinase 1
#14803
middle Confidence
Subject:
lesional_cells
(Tumor-associated cells)
→
are_negative_for
→
Object:
c-KIT
(Receptor tyrosine kinases)
Original: lesional cells#are negative for#CD21/ smooth muscle actin/ ckit/ cytokeratins/ and anaplastic lymphoma kinase 1
#14802
middle Confidence
Subject:
lesional_cells
(Tumor-associated cells)
→
are_negative_for
→
Object:
smooth_muscle_actin
(Cytoskeletal proteins)
Original: lesional cells#are negative for#CD21/ smooth muscle actin/ ckit/ cytokeratins/ and anaplastic lymphoma kinase 1
#14801
middle Confidence
Subject:
lesional_cells
(Tumor-associated cells)
→
are_negative_for
→
Object:
CD21
(Surface markers)
Original: lesional cells#are negative for#CD21/ smooth muscle actin/ ckit/ cytokeratins/ and anaplastic lymphoma kinase 1
#14797
middle Confidence
Subject:
Adenoid_squamous_cell_carcinoma
(Tumor type)
→
is_described_as
→
Object:
poorly_differentiated_variant
(Tumor morphological subtypes)
Original: Adenoid squamous cell carcinoma#is described as#a poorly differentiated variant of the tumor with aggressive behavior
#14796
middle Confidence
Subject:
immunocytochemistry
(Diagnostic techniques)
→
is_useful_for
→
Object:
fluorescent_marker_expression
(Protein expression)
Original: Immunocytochemistry#is#a useful diagnostic technique for determining fluorescent marker expression
#14795
middle Confidence
Subject:
immunocytochemistry
(Diagnostic techniques)
→
is
→
Object:
diagnostic_technique
(Diagnostic Methods)
Original: Immunocytochemistry#is#a useful diagnostic technique for determining fluorescent marker expression
#14787
middle Confidence
Subject:
cytoplasm_of_rhabdoid_cells
(Cellular substructure)
→
shows
→
Object:
positivity_for_cytokeratin
(Protein expression)
Original: cytoplasm of rhabdoid cells#shows#positivity for vimentin and/or cytokeratin
#14786
middle Confidence
Subject:
cytoplasm_of_rhabdoid_cells
(Cellular substructure)
→
shows
→
Object:
positivity_for_vimentin
(Protein expression)
Original: cytoplasm of rhabdoid cells#shows#positivity for vimentin and/or cytokeratin
#14778
middle Confidence
Subject:
MCRERs
(Molecular markers)
→
have_diagnostic_value_for
→
Object:
pancreatic_cancer
(Tumor)
Original: Cytodiagnostic pitfalls of pancreatic cancer#are discussed with#diagnostic value of MCRERs
#14777
middle Confidence
Subject:
epithelioid_cells_with_uniform_nuclei_and_inconspicuous_nucleoli
(Epithelioid cells)
→
suggests
→
Object:
benign_myoepithelioma
(Benign myoepithelioma)
Original: Spindle cells and epithelioid cells with uniform nuclei and inconspicuous nucleoli#suggest#benign myoepithelioma
#14776
middle Confidence
Subject:
spindle_cells
(Spindle cells)
→
suggests
→
Object:
benign_myoepithelioma
(Benign myoepithelioma)
Original: Spindle cells and epithelioid cells with uniform nuclei and inconspicuous nucleoli#suggest#benign myoepithelioma
#14775
middle Confidence
Subject:
presence_of_single_cells
(Single Cell)
→
improves
→
Object:
diagnostic_accuracy_for_small_cell_carcinoma
(Diagnostic Accuracy)
Original: Moderate necrosis (<50%) and presence of single cells#improves#diagnostic accuracy for small cell carcinoma
#14774
middle Confidence
Subject:
moderate_necrosis_<50%
(Moderate necrosis <50%)
→
improves
→
Object:
diagnostic_accuracy_for_small_cell_carcinoma
(Diagnostic Accuracy)
Original: Moderate necrosis (<50%) and presence of single cells#improves#diagnostic accuracy for small cell carcinoma
#14747
middle Confidence
Subject:
histology
(Histological examination)
→
is_difficult_for
→
Object:
differentiation_of_carcinoma
(Malignant tumors)
Original: differentiation between parathyroid adenoma/ atypical adenoma and carcinoma#is difficult on#histology
#14746
middle Confidence
Subject:
histology
(Histological examination)
→
is_difficult_for
→
Object:
differentiation_of_atypical_adenoma
(Benign tumors)
Original: differentiation between parathyroid adenoma/ atypical adenoma and carcinoma#is difficult on#histology
#14745
middle Confidence
Subject:
histology
(Histological examination)
→
is_difficult_for
→
Object:
differentiation_of_parathyroid_adenoma
(Benign tumors)
Original: differentiation between parathyroid adenoma/ atypical adenoma and carcinoma#is difficult on#histology
#14727
middle Confidence
Subject:
A1AAT
(Tumor markers)
→
is_positive_in
→
Object:
hepatoid_tumor_cells
(Tumor cells)
Original: Tumor cells in hepatoid areas#were positive with#AFP/ alpha-1-antitrypsin (A1AAT)/ and albumin antisera
#14726
middle Confidence
Subject:
AFP
(Tumor markers)
→
is_positive_in
→
Object:
hepatoid_tumor_cells
(Tumor cells)
Original: Tumor cells in hepatoid areas#were positive with#AFP/ alpha-1-antitrypsin (A1AAT)/ and albumin antisera
#14725
middle Confidence
Subject:
clinical_characteristics_of_CPE_adenomas
(Clinical characteristics)
→
may_be_helpful_for
→
Object:
differentiation_from_ciliary_body_malignant_melanomas
(Diagnostic Process)
Original: Clinical characteristics of CPE adenomas#may be helpful for#differentiation from ciliary body malignant melanomas
#14724
middle Confidence
Subject:
ciliary_pigment_epithelium_adenomas
(Benign tumors)
→
are_differentiated_from
→
Object:
ciliary_body_melanomas
(Malignant tumors)
Original: Adenomas of the ciliary pigment epithelium (CPE)#are rare benign tumours#differentiated from malignant ciliary body melanomas
#14723
middle Confidence
Subject:
Immunohistochemistry
(Detection Technology)
→
distinguishes
→
Object:
CIS
(Tumor type)
Original: The present study#aimed to distinguish#ASE from CIS using immunohistochemistry
#14722
middle Confidence
Subject:
Immunohistochemistry
(Detection Technology)
→
distinguishes
→
Object:
ASE
(Histological subtype)
Original: The present study#aimed to distinguish#ASE from CIS using immunohistochemistry
#14721
middle Confidence
Subject:
CD44
(Cell adhesion molecules)
→
shows_differential_expression_in
→
Object:
carcinoma_in_situ
(Tumor type)
Original: Differential immunohistochemical expression#of DEC1/ CK/ and CD44#in oral atypical squamous epithelium and carcinoma in situ
#14720
middle Confidence
Subject:
CD44
(Cell adhesion molecules)
→
shows_differential_expression_in
→
Object:
oral_atypical_squamous_epithelium
(Organization Type)
Original: Differential immunohistochemical expression#of DEC1/ CK/ and CD44#in oral atypical squamous epithelium and carcinoma in situ
#14719
middle Confidence
Subject:
CK
(Cytokeratin)
→
shows_differential_expression_in
→
Object:
carcinoma_in_situ
(Tumor type)
Original: Differential immunohistochemical expression#of DEC1/ CK/ and CD44#in oral atypical squamous epithelium and carcinoma in situ
#14718
middle Confidence
Subject:
CK
(Cytokeratin)
→
shows_differential_expression_in
→
Object:
oral_atypical_squamous_epithelium
(Organization Type)
Original: Differential immunohistochemical expression#of DEC1/ CK/ and CD44#in oral atypical squamous epithelium and carcinoma in situ
#14717
middle Confidence
Subject:
1-Dec
(Transcription Factors)
→
shows_differential_expression_in
→
Object:
carcinoma_in_situ
(Tumor type)
Original: Differential immunohistochemical expression#of DEC1/ CK/ and CD44#in oral atypical squamous epithelium and carcinoma in situ
#14716
middle Confidence
Subject:
1-Dec
(Transcription Factors)
→
shows_differential_expression_in
→
Object:
oral_atypical_squamous_epithelium
(Organization Type)
Original: Differential immunohistochemical expression#of DEC1/ CK/ and CD44#in oral atypical squamous epithelium and carcinoma in situ
#14715
middle Confidence
Subject:
Nucleoli
(Nuclear components)
→
are_invariably_present_in
→
Object:
rhabdoid_tumors
(Tumor type)
Original: Nucleoli#are invariably present#in rhabdoid tumors
#14676
middle Confidence
Subject:
Chromogranin
(Chromogranin)
→
exemplifies
→
Object:
neuroendocrine_differentiation
(Cellular Processes)
Original: Cytoplasmic synaptophysin and chromogranin positivity#exemplify#neuroendocrine differentiation in Merkel cell carcinoma
#14675
middle Confidence
Subject:
synaptophysin
(Synaptophysin)
→
exemplifies
→
Object:
neuroendocrine_differentiation
(Cellular Processes)
Original: Cytoplasmic synaptophysin and chromogranin positivity#exemplify#neuroendocrine differentiation in Merkel cell carcinoma
#14668
middle Confidence
Subject:
FNA_cytology
(Cytology)
→
revealed
→
Object:
clusters_of_malignant_oval-to-polygonal-shaped_cells
(Cell morphology)
Original: FNA cytology#revealed#clusters of malignant oval-to-polygonal-shaped cells
#14656
middle Confidence
Subject:
tumor_tissue_infiltrating_lymphatics
(Tumor-related tissue)
→
shows_positive_expression_of
→
Object:
MAK-6
(Cytokeratin)
Original: Tumor tissue infiltrating lymphatics#demonstrated#positive staining for EMA and keratins CAM-5.2/ AE1/AE3/ MAK-6
#14655
middle Confidence
Subject:
tumor_tissue_infiltrating_lymphatics
(Tumor-related tissue)
→
shows_positive_expression_of
→
Object:
AE1/AE3
(Cytokeratin)
Original: Tumor tissue infiltrating lymphatics#demonstrated#positive staining for EMA and keratins CAM-5.2/ AE1/AE3/ MAK-6
#14654
middle Confidence
Subject:
tumor_tissue_infiltrating_lymphatics
(Tumor-related tissue)
→
shows_positive_expression_of
→
Object:
CAM-5.2
(Cytokeratin)
Original: Tumor tissue infiltrating lymphatics#demonstrated#positive staining for EMA and keratins CAM-5.2/ AE1/AE3/ MAK-6
#14653
middle Confidence
Subject:
tumor_tissue_infiltrating_lymphatics
(Tumor-related tissue)
→
shows_positive_expression_of
→
Object:
EMA
(epithelial cell differentiation antigen)
Original: Tumor tissue infiltrating lymphatics#demonstrated#positive staining for EMA and keratins CAM-5.2/ AE1/AE3/ MAK-6
#14652
middle Confidence
Subject:
TCC
(Tumor type)
→
shows_focal_expression_of
→
Object:
keratin_34_beta_E12
(Cytokeratin)
Original: TCC#was focally positive for#keratin detectable by antibody 34 beta E12
#14647
middle Confidence
Subject:
MFH_of_the_lung
(Tumor type)
→
must_be_carefully_evaluated_to
→
Object:
rule_out_lung_tumor
(Diagnostic workup)
Original: MFH of the lung#must be carefully evaluated#to rule out a metastatic origin
#14646
middle Confidence
Subject:
MFH_of_the_lung
(Tumor type)
→
must_be_carefully_evaluated_to
→
Object:
rule_out_metastatic_origin
(Diagnostic workup)
Original: MFH of the lung#must be carefully evaluated#to rule out a metastatic origin
#14584
middle Confidence
Subject:
overall_features
(Histological characteristics)
→
were_identical_to
→
Object:
low-grade_papillary_Schneiderian_carcinoma
(Disease Type)
Original: The overall features#were identical to#those of a recent report of a low-grade papillary Schneiderian carcinoma
#14564
middle Confidence
Subject:
ectopic_pancreas
(Ectopic pancreas)
→
is_characterized_by
→
Object:
cystically_dilated_duct_structures
(Cystic dilatation catheter structure)
Original: ectopic pancreas#is characterized by#cystically dilated duct structures
#14560
middle Confidence
Subject:
cytological_smears
(Cytology specimens)
→
were_found_in
→
Object:
hyperplasia
(Hyperplasia)
Original: Cytological smears#were found in#28 cases/ with 21 cases surgically resected
#14559
middle Confidence
Subject:
cytological_smears
(Cytology specimens)
→
were_found_in
→
Object:
carcinomas
(cancer)
Original: Cytological smears#were found in#28 cases/ with 21 cases surgically resected
#14558
middle Confidence
Subject:
cytological_smears
(Cytology specimens)
→
were_found_in
→
Object:
adenomas
(Adenoma)
Original: Cytological smears#were found in#28 cases/ with 21 cases surgically resected
#14545
middle Confidence
Subject:
Histopathological_studies
(Histological examination)
→
demonstrated
→
Object:
diffuse_proliferation_of_large-sized_lymphocytes
(Organizational form)
Original: Histopathological studies#demonstrated#diffuse proliferation of large-sized lymphocytes
#14544
middle Confidence
Subject:
Adenosis of the prostate
(Organizational form)
→
is_characterized_by
→
Object:
proliferation_of_benign_glands
(Organizational form)
Original: Adenosis of the prostate#is characterized by#a well-circumscribed proliferation of benign glands
#14534
middle Confidence
Subject:
AIS_smears
(Cytology samples)
→
show
→
Object:
increased_nuclear_to_cytoplasmic_ratio
(Cell structure)
Original: AIS smears#show#increased nuclear to cytoplasmic ratios
#14527
middle Confidence
Subject:
FDC_tumors
(Tumor)
→
arise_in
→
Object:
liver
(Anatomical location)
Original: FDC tumors#arise in#lymph nodes and extranodal sites including oral cavity/ tonsil/ gastrointestinal tract/ and liver
#14526
middle Confidence
Subject:
FDC_tumors
(Tumor)
→
arise_in
→
Object:
gastrointestinal_tract
(Anatomical location)
Original: FDC tumors#arise in#lymph nodes and extranodal sites including oral cavity/ tonsil/ gastrointestinal tract/ and liver
#14525
middle Confidence
Subject:
FDC_tumors
(Tumor)
→
arise_in
→
Object:
tonsil
(Anatomical location)
Original: FDC tumors#arise in#lymph nodes and extranodal sites including oral cavity/ tonsil/ gastrointestinal tract/ and liver
#14524
middle Confidence
Subject:
FDC_tumors
(Tumor)
→
arise_in
→
Object:
oral_cavity
(Anatomical location)
Original: FDC tumors#arise in#lymph nodes and extranodal sites including oral cavity/ tonsil/ gastrointestinal tract/ and liver
#14523
middle Confidence
Subject:
FDC_tumors
(Tumor)
→
arise_in
→
Object:
lymph_nodes
(Anatomical location)
Original: FDC tumors#arise in#lymph nodes and extranodal sites including oral cavity/ tonsil/ gastrointestinal tract/ and liver
#14522
middle Confidence
Subject:
follicular_dendritic_cell_sarcoma
(Rare tumors)
→
occurs_in
→
Object:
lymph_nodes
(Anatomical location)
Original: follicular dendritic cell sarcoma#is a rare entity in#lymph nodes
#14521
middle Confidence
Subject:
follicular_dendritic_cell_sarcoma
(Rare tumors)
→
is_a
→
Object:
rare_entity
(Disease phenotype)
Original: follicular dendritic cell sarcoma#is a rare entity in#lymph nodes
#14513
middle Confidence
Subject:
adenosis
(Benign glandular lesions)
→
is_characterized_by
→
Object:
merging_of_small_crowded_glands_with_surrounding_benign_glands
(Organizational structure characteristics)
Original: adenosis#is characterized by#merging of small crowded glands with surrounding benign glands
#14510
middle Confidence
Subject:
criteria
(Diagnostic criteria)
→
distinguish
→
Object:
reactive_benign_changes
(Benign reactive changes)
Original: criteria#distinguish#clinically significant lesions from reactive benign changes
#14509
middle Confidence
Subject:
criteria
(Diagnostic criteria)
→
distinguish
→
Object:
clinically_significant_lesions
(Disease phenotype)
Original: criteria#distinguish#clinically significant lesions from reactive benign changes
#14475
middle Confidence
Subject:
FNA_smears
(Cytology samples)
→
showed
→
Object:
prominent_nucleoli
(Cytological characteristics)
Original: FNA smears from CFA cases#showed#discohesiveness/ enlarged nuclei/ and prominent nucleoli
#14474
middle Confidence
Subject:
FNA_smears
(Cytology samples)
→
showed
→
Object:
enlarged_nuclei
(Cytological characteristics)
Original: FNA smears from CFA cases#showed#discohesiveness/ enlarged nuclei/ and prominent nucleoli
#14473
middle Confidence
Subject:
FNA_smears
(Cytology samples)
→
showed
→
Object:
Discohesiveness
(Cytological characteristics)
Original: FNA smears from CFA cases#showed#discohesiveness/ enlarged nuclei/ and prominent nucleoli
#14435
middle Confidence
Subject:
malignant_signet-ring_cells
(Tumor cells)
→
stain_with
→
Object:
melanoma_cocktail
(Protein complex)
Original: malignant signet-ring cells#stain with#S100/ vimentin/ and melanoma cocktail
#14434
middle Confidence
Subject:
malignant_signet-ring_cells
(Tumor cells)
→
stain_with
→
Object:
vimentin
(protein)
Original: malignant signet-ring cells#stain with#S100/ vimentin/ and melanoma cocktail
#14433
middle Confidence
Subject:
malignant_signet-ring_cells
(Tumor cells)
→
stain_with
→
Object:
S100
(protein)
Original: malignant signet-ring cells#stain with#S100/ vimentin/ and melanoma cocktail
#14432
middle Confidence
Subject:
FNA_smears
(Test samples)
→
are_cellular_with
→
Object:
small_ovoid_to_spindled_cells
(Cell morphology)
Original: FNA smears#are cellular with#small ovoid to spindled cells
#14431
middle Confidence
Subject:
fine_needle_aspiration
(Detection Methods)
→
reveals
→
Object:
malignant_cells_from_poorly_differentiated_carcinoma
(Tumor cells)
Original: fine needle aspiration#reveals#malignant cells from a poorly differentiated carcinoma
#14429
middle Confidence
Subject:
nuclear_enlargement
(Cell morphology)
→
is_associated_with
→
Object:
finely_granular_chromatin
(Cell morphology)
Original: nuclear enlargement#is associated with#oval-to-round shape/ prominent nucleoli/ and finely granular chromatin
#14428
middle Confidence
Subject:
nuclear_enlargement
(Cell morphology)
→
is_associated_with
→
Object:
prominent_nucleoli
(Cell morphology)
Original: nuclear enlargement#is associated with#oval-to-round shape/ prominent nucleoli/ and finely granular chromatin
#14427
middle Confidence
Subject:
nuclear_enlargement
(Cell morphology)
→
is_associated_with
→
Object:
oval_to_round_shape
(Cell morphology)
Original: nuclear enlargement#is associated with#oval-to-round shape/ prominent nucleoli/ and finely granular chromatin
#14426
middle Confidence
Subject:
increased_inflammatory_cells
(Immune cell infiltration)
→
support
→
Object:
diagnosis_of_reactive_hepatitis
(Diagnosis conclusion)
Original: Reactive hepatitis#is diagnosed based on#moderate reactive nuclear patterns and increased inflammatory cells
#14425
middle Confidence
Subject:
moderate_reactive_nuclear_patterns
(Nuclear reaction characteristics)
→
support
→
Object:
diagnosis_of_reactive_hepatitis
(Diagnosis conclusion)
Original: Reactive hepatitis#is diagnosed based on#moderate reactive nuclear patterns and increased inflammatory cells
#14424
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_associated_with
→
Object:
metastatic_carcinoma
(Tumor diseases)
Original: Clusters of epithelial cells#intermix with#normal hepatocytes/ indicative of metastatic or cholangiocellular carcinoma
#14423
middle Confidence
Subject:
Aspirate
(Clinical operation samples)
→
yields
→
Object:
highly_cellular_smears
(Cytological phenotype)
Original: Aspirate#yields#highly cellular smears with small/ slightly atypical cells in multilayered groups
#14421
middle Confidence
Subject:
CZ_epithelium
(Cell Type)
→
is_recognized_as
→
Object:
benign_constituent_of_prostate_cytology
(Histological characteristics)
Original: CZ epithelium#is recognized as#a benign constituent of prostate cytology
#14417
middle Confidence
Subject:
cytomorphological_features
(Cytological characteristics)
→
are_presented_in
→
Object:
histopathologically_confirmed_SCNEC_cases
(Pathological diagnosis cases)
Original: cytomorphological features#are presented#in histopathologically confirmed cases of cervical SCNEC
#14416
middle Confidence
Subject:
magnetic_resonance_imaging
(Imaging technology)
→
revealed
→
Object:
brain_nodular_lesions
(Pathological changes in the brain)
Original: magnetic resonance imaging#revealed#multiple nodular lesions in the brain
#14415
middle Confidence
Subject:
bland_epithelial_cells
(Epithelial cells)
→
exhibit
→
Object:
inconspicuous_nucleoli
(Cell morphology)
Original: tumor#composed of#bland epithelial cells with round nuclei/ delicate chromatin/ and inconspicuous nucleoli
#14414
middle Confidence
Subject:
bland_epithelial_cells
(Epithelial cells)
→
exhibit
→
Object:
delicate_chromatin
(Cell morphology)
Original: tumor#composed of#bland epithelial cells with round nuclei/ delicate chromatin/ and inconspicuous nucleoli
#14413
middle Confidence
Subject:
bland_epithelial_cells
(Epithelial cells)
→
exhibit
→
Object:
round_nuclei
(Cell morphology)
Original: tumor#composed of#bland epithelial cells with round nuclei/ delicate chromatin/ and inconspicuous nucleoli
#14412
middle Confidence
Subject:
tumor
(Tumor tissue)
→
composed_of
→
Object:
bland_epithelial_cells
(Epithelial cells)
Original: tumor#composed of#bland epithelial cells with round nuclei/ delicate chromatin/ and inconspicuous nucleoli
#14398
middle Confidence
Subject:
Reed-Sternberg-like_large_cells
(Tumor cells)
→
are_labeled_by
→
Object:
antibodies_against_CD30_antigen
(Antibody)
Original: Reed-Sternberg-like large cells#are labeled by#antibodies against CD30 antigen
#14395
middle Confidence
Subject:
endocervical_adenocarcinoma_in_situ_(AIS)
(Tumor tissue)
→
shows
→
Object:
cytologic_features_in_ThinPrep_slides
(Cell morphology)
Original: endocervical adenocarcinoma in situ (AIS)#shows#cytologic features in ThinPrep slides
#14385
middle Confidence
Subject:
clinical_history_of_treatment_with_radioactive_iodine
(Medical history information)
→
is_a_clue_to
→
Object:
benign_nature_of_nodules
(Disease status)
Original: clinical history of treatment with radioactive iodine#is a clue to#benign nature of nodules
#14384
middle Confidence
Subject:
benign_nodules
(Disease status)
→
exhibit
→
Object:
Hürthle_cells
(Special cell types)
Original: benign nodules#exhibit#presence of lymphocytes/ histiocytes/ colloid/ cytoplasmic vacuoles/ and Hürthle cells
#14383
middle Confidence
Subject:
benign_nodules
(Disease status)
→
exhibit
→
Object:
histiocytes
(Immune cells)
Original: benign nodules#exhibit#presence of lymphocytes/ histiocytes/ colloid/ cytoplasmic vacuoles/ and Hürthle cells
#14382
middle Confidence
Subject:
benign_nodules
(Disease status)
→
exhibit
→
Object:
lymphocytes
(Immune cells)
Original: benign nodules#exhibit#presence of lymphocytes/ histiocytes/ colloid/ cytoplasmic vacuoles/ and Hürthle cells
#14381
middle Confidence
Subject:
benign_nodules
(Disease status)
→
are_characterized_by
→
Object:
flat_sheets
(Histological characteristics)
Original: benign nodules#are characterized by#architectural arrangement of cells in cohesive clusters and flat sheets
#14380
middle Confidence
Subject:
benign_nodules
(Disease status)
→
are_characterized_by
→
Object:
architectural_arrangement_of_cells_in_cohesive_clusters
(Histological characteristics)
Original: benign nodules#are characterized by#architectural arrangement of cells in cohesive clusters and flat sheets
#14379
middle Confidence
Subject:
malignancy
(Disease status)
→
is_associated_with
→
Object:
blue-tinged_mucin
(Extracellular substances)
Original: malignancy#is associated with#mitoses and blue-tinged mucin
#14378
middle Confidence
Subject:
malignancy
(Disease status)
→
is_associated_with
→
Object:
Mitoses
(Cellular Processes)
Original: malignancy#is associated with#mitoses and blue-tinged mucin
#14377
middle Confidence
Subject:
pseudohyperplastic_foci
(Histological structure)
→
exhibit
→
Object:
crystalloids
(Intracellular structure)
Original: pseudohyperplastic foci#exhibit#crystalloids in 45% of cases
#14373
middle Confidence
Subject:
Primary_tumor
(Tumor)
→
shows
→
Object:
Necrosis
(Cell morphology)
Original: Primary tumor#highlighted#microcystic/ papillary/ and solid architecture with eosinophilic cytoplasm/ vesicular nuclei/ prominent nucleoli/ abundant mitotic figures/ and necrosis
#14372
middle Confidence
Subject:
Primary_tumor
(Tumor)
→
shows
→
Object:
abundant_mitotic_figures
(Cell morphology)
Original: Primary tumor#highlighted#microcystic/ papillary/ and solid architecture with eosinophilic cytoplasm/ vesicular nuclei/ prominent nucleoli/ abundant mitotic figures/ and necrosis
#14371
middle Confidence
Subject:
Primary_tumor
(Tumor)
→
shows
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Primary tumor#highlighted#microcystic/ papillary/ and solid architecture with eosinophilic cytoplasm/ vesicular nuclei/ prominent nucleoli/ abundant mitotic figures/ and necrosis
#14370
middle Confidence
Subject:
Primary_tumor
(Tumor)
→
shows
→
Object:
vesicular_nuclei
(Cell morphology)
Original: Primary tumor#highlighted#microcystic/ papillary/ and solid architecture with eosinophilic cytoplasm/ vesicular nuclei/ prominent nucleoli/ abundant mitotic figures/ and necrosis
#14369
middle Confidence
Subject:
Primary_tumor
(Tumor)
→
shows
→
Object:
eosinophilic_cytoplasm
(Cell morphology)
Original: Primary tumor#highlighted#microcystic/ papillary/ and solid architecture with eosinophilic cytoplasm/ vesicular nuclei/ prominent nucleoli/ abundant mitotic figures/ and necrosis
#14368
middle Confidence
Subject:
Primary_tumor
(Tumor)
→
shows
→
Object:
solid_architecture
(Organizational structure characteristics)
Original: Primary tumor#highlighted#microcystic/ papillary/ and solid architecture with eosinophilic cytoplasm/ vesicular nuclei/ prominent nucleoli/ abundant mitotic figures/ and necrosis
#14367
middle Confidence
Subject:
Primary_tumor
(Tumor)
→
shows
→
Object:
papillary_architecture
(Organizational structure characteristics)
Original: Primary tumor#highlighted#microcystic/ papillary/ and solid architecture with eosinophilic cytoplasm/ vesicular nuclei/ prominent nucleoli/ abundant mitotic figures/ and necrosis
#14366
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
variable_hyperchromasia
(Cell morphology)
Original: Tumor cells#had#high nuclear:cytoplasmic ratios/ irregular nuclei/ prominent nucleoli/ and variable hyperchromasia
#14365
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Tumor cells#had#high nuclear:cytoplasmic ratios/ irregular nuclei/ prominent nucleoli/ and variable hyperchromasia
#14364
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
irregular_nuclei
(Cell morphology)
Original: Tumor cells#had#high nuclear:cytoplasmic ratios/ irregular nuclei/ prominent nucleoli/ and variable hyperchromasia
#14363
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
high_nuclear_cytoplasmic_ratio
(Cell morphology)
Original: Tumor cells#had#high nuclear:cytoplasmic ratios/ irregular nuclei/ prominent nucleoli/ and variable hyperchromasia
#14360
middle Confidence
Subject:
atypical_cells
(Abnormal cells)
→
expresses
→
Object:
CD20
(Leukocyte differentiation antigen)
Original: atypical cells#displayed immunoreactivity for#CD45RB and CD20
#14359
middle Confidence
Subject:
atypical_cells
(Abnormal cells)
→
expresses
→
Object:
CD45RB
(Leukocyte differentiation antigen)
Original: atypical cells#displayed immunoreactivity for#CD45RB and CD20
#14358
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
expresses
→
Object:
PAX8
(Transcription Factors)
Original: neoplastic cells#were immunoreactive for#CD10/ PR/ ER/ and PAX8
#14357
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
expresses
→
Object:
ESR1
(Hormone receptor proteins)
Original: neoplastic cells#were immunoreactive for#CD10/ PR/ ER/ and PAX8
#14356
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
expresses
→
Object:
PGR
(Hormone receptor proteins)
Original: neoplastic cells#were immunoreactive for#CD10/ PR/ ER/ and PAX8
#14355
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
expresses
→
Object:
CD10
(Cell surface molecules)
Original: neoplastic cells#were immunoreactive for#CD10/ PR/ ER/ and PAX8
#14354
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
expresses
→
Object:
synaptophysin
(Synaptic proteins)
Original: Tumor cells#were focally positive for#pankeratin/ keratin 7/ synaptophysin
#14353
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
expresses
→
Object:
keratin_7
(Cytoskeletal proteins)
Original: Tumor cells#were focally positive for#pankeratin/ keratin 7/ synaptophysin
#14352
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
expresses
→
Object:
pankeratin
(Cytoskeletal proteins)
Original: Tumor cells#were focally positive for#pankeratin/ keratin 7/ synaptophysin
#14345
middle Confidence
Subject:
hyaline_cytoplasmic_globules
(Cell structure)
→
appear_diagnostic_of
→
Object:
BCH
(disease)
Original: Hyaline cytoplasmic globules#appear diagnostic of#BCH
#14344
middle Confidence
Subject:
RDD
(disease)
→
is_considered_in
→
Object:
differential_diagnosis_of_pancreatic_masses
(Clinical diagnostic process)
Original: RDD#is considered in#differential diagnosis of pancreatic masses
#14340
middle Confidence
Subject:
histopathological_evaluation
(Histopathological evaluation)
→
revealed
→
Object:
pancreatic_mass_with_RDD_features
(Disease phenotype)
Original: Histopathological evaluation#revealed#a pancreatic mass with characteristic features of RDD
#14293
middle Confidence
Subject:
Prominent_nucleoli
(Nuclear characteristics)
→
is_characteristic_finding_of
→
Object:
GAS
(Tumor subtype)
Original: Characteristic cytologic findings of GAS#include#vesicular nuclei with prominent nucleoli
#14292
middle Confidence
Subject:
Vesicular_nuclei
(Nuclear characteristics)
→
is_characteristic_finding_of
→
Object:
GAS
(Tumor subtype)
Original: Characteristic cytologic findings of GAS#include#vesicular nuclei with prominent nucleoli
#14291
middle Confidence
Subject:
Intracytoplasmic_neutrophil_entrapment
(Intracellular structure)
→
is_characteristic_finding_of
→
Object:
GAS
(Tumor subtype)
Original: Characteristic cytologic findings of GAS#include#intracytoplasmic neutrophil entrapment
#14290
middle Confidence
Subject:
Foamy_cytoplasm
(Cytoplasmic characteristics)
→
is_characteristic_finding_of
→
Object:
GAS
(Tumor subtype)
Original: Characteristic cytologic findings of GAS#include#vacuolar and/or foamy cytoplasm
#14289
middle Confidence
Subject:
Vacuolar_cytoplasm
(Cytoplasmic characteristics)
→
is_characteristic_finding_of
→
Object:
GAS
(Tumor subtype)
Original: Characteristic cytologic findings of GAS#include#vacuolar and/or foamy cytoplasm
#14288
middle Confidence
Subject:
Honeycomb_sheets
(Cell morphology)
→
is_characteristic_finding_of
→
Object:
GAS
(Tumor subtype)
Original: Characteristic cytologic findings of GAS#include#monolayered and honeycomb sheets
#14287
middle Confidence
Subject:
Monolayered_sheets
(Cell morphology)
→
is_characteristic_finding_of
→
Object:
GAS
(Tumor subtype)
Original: Characteristic cytologic findings of GAS#include#monolayered and honeycomb sheets
#14286
middle Confidence
Subject:
Conspicuous_nucleoli
(Nuclear characteristics)
→
is_present_in
→
Object:
GAS
(Tumor subtype)
Original: Conspicuous nucleoli#were present in#nine patients with GAS
#14285
middle Confidence
Subject:
Vesicular_nuclei
(Nuclear characteristics)
→
is_present_in
→
Object:
GAS
(Tumor subtype)
Original: Nuclei#were vesicular in#eight patients with GAS
#14284
middle Confidence
Subject:
Intracytoplasmic_mucin
(Cell components)
→
is_present_in
→
Object:
GAS
(Tumor subtype)
Original: Intracytoplasmic mucin#was present in#eight patients with GAS
#14184
middle Confidence
Subject:
CT-guided_biopsy
(Diagnostic techniques)
→
suggested
→
Object:
mesothelioma_of_epithelioid_type
(Disease classification)
Original: CT-guided biopsy#suggested#mesothelioma of epithelioid type
#14164
middle Confidence
Subject:
fibroadenoma
(Benign tumors)
→
exhibited
→
Object:
very_cellular_smears_with_marked_discohesiveness
(Cytological characteristics)
Original: Fibroadenomas#exhibited#very cellular smears with marked discohesiveness/ occasional nuclear atypia/ and prominent nucleoli
#14139
middle Confidence
Subject:
cervical_smears_of_UPSC_patients
(Pathological samples)
→
revealed
→
Object:
papillary_clusters_composed_of_large_pleomorphic_tumor_cells
(Tumor cell morphology)
Original: cervical smears of patients with UPSC#revealed#papillary clusters composed of large pleomorphic tumor cells
#14138
middle Confidence
Subject:
large_eosinophilic_epithelioid_cells
(Tumor cell morphology)
→
showed
→
Object:
prominent_eosinophilic_nucleoli
(Nucleolar morphology)
Original: Lesions#showed#large eosinophilic epithelioid cells with irregular ovoid nuclei and prominent eosinophilic nucleoli
#14137
middle Confidence
Subject:
large_eosinophilic_epithelioid_cells
(Tumor cell morphology)
→
showed
→
Object:
irregular_ovoid_nuclei
(Nuclear morphology)
Original: Lesions#showed#large eosinophilic epithelioid cells with irregular ovoid nuclei and prominent eosinophilic nucleoli
#14133
middle Confidence
Subject:
β-catenin_immunocytochemistry
(Immunocytochemistry)
→
is_biomarker_for
→
Object:
CVPTC
(disease)
Original: Preoperative diagnosis of CVPTC#can be made by#cytologic features and β-catenin immunocytochemistry
#14132
middle Confidence
Subject:
cytologic_features
(Morphological characteristics)
→
are_biomarker_for
→
Object:
CVPTC
(disease)
Original: Preoperative diagnosis of CVPTC#can be made by#cytologic features and β-catenin immunocytochemistry
#14128
middle Confidence
Subject:
carcinomas_of_the_breast
(Tumor)
→
are_commonly_associated_with
→
Object:
lymphoplasmacytic_background_in_cytology
(Tissue Microenvironment)
Original: Carcinomas of the breast#are commonly associated with#lymphoplasmacytic background in cytology
#14117
middle Confidence
Subject:
ascitic_fluid
(Body fluid samples)
→
reveals
→
Object:
clusters_of_round_plump_cells_with_hyperchromatic_nuclei_and_prominent_nucleoli
(Tumor cell morphology)
Original: ascitic fluid#reveals#clusters of round plump cells with hyperchromatic nuclei and prominent nucleoli
#14116
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: tumor cells#are positive for#vimentin
#14096
middle Confidence
Subject:
42_year_old_woman
(Patient characteristics)
→
presented_with
→
Object:
abdominal_pain
(Clinical symptoms)
Original: 42-year-old woman#presented with#abdominal pain
#14085
middle Confidence
Subject:
cytology_samples
(Sample Type)
→
are_compared_for
→
Object:
cytomorphologic_features
(Cell morphology)
Original: cytology samples#are compared for#cytomorphologic features including nucleoli
#14082
middle Confidence
Subject:
diagnostic_cytologic_features
(Cytological characteristics)
→
include
→
Object:
basaloid_cells
(Cell Type)
Original: diagnostic cytologic features#include#basaloid cells with high nuclear-cytoplasmic ratio and nucleoli
#14067
middle Confidence
Subject:
AT/RT_cells
(Tumor cells)
→
have_morphology
→
Object:
large_cells_with_pleomorphic_nuclei_prominent_nucleoli_cytoplasmic_inclusions
(Cell morphology)
Original: The CSF cytomorphologic findings of AT/RT cells#are#large cells with pleomorphic nuclei/ prominent nucleoli/ and cytoplasmic inclusions
#14042
middle Confidence
Subject:
bone_epithelioid_angiosarcoma
(Tumor diseases)
→
is_characterized_by
→
Object:
pleomorphic_epithelioid_cells
(Cell morphology)
Original: bone epithelioid angiosarcoma#is characterized by#pleomorphic epithelioid cells
#14027
middle Confidence
Subject:
EAML
(Tumor type)
→
differential_diagnosis_with
→
Object:
FH-deficient_RCC
(Tumor type)
Original: findings#are discussed in#the context of differential diagnosis of EAML and FH-deficient RCC
#14025
middle Confidence
Subject:
adenocarcinoma
(Malignant tumors)
→
arises_in
→
Object:
pleomorphic_adenoma
(Benign tumors)
Original: Histological examination#revealed#tumor composed of benign pleomorphic adenoma and adenocarcinomatous component
#14024
middle Confidence
Subject:
pleomorphic_adenoma
(Benign tumors)
→
coexists_with
→
Object:
adenocarcinoma
(Malignant tumors)
Original: Histological examination#revealed#tumor composed of benign pleomorphic adenoma and adenocarcinomatous component
#13958
middle Confidence
Subject:
naked_nuclei
(Nuclear characteristics)
→
is_shown_in
→
Object:
JGCT
(disease)
Original: AGCTs and JGCT#showed#hypercellularity/ clusters/ sheets/ and naked nuclei
#13957
middle Confidence
Subject:
naked_nuclei
(Nuclear characteristics)
→
is_shown_in
→
Object:
AGCT
(disease)
Original: AGCTs and JGCT#showed#hypercellularity/ clusters/ sheets/ and naked nuclei
#13956
middle Confidence
Subject:
sheets
(Cytological characteristics)
→
is_shown_in
→
Object:
JGCT
(disease)
Original: AGCTs and JGCT#showed#hypercellularity/ clusters/ sheets/ and naked nuclei
#13955
middle Confidence
Subject:
sheets
(Cytological characteristics)
→
is_shown_in
→
Object:
AGCT
(disease)
Original: AGCTs and JGCT#showed#hypercellularity/ clusters/ sheets/ and naked nuclei
#13954
middle Confidence
Subject:
clusters
(Cytological characteristics)
→
is_shown_in
→
Object:
JGCT
(disease)
Original: AGCTs and JGCT#showed#hypercellularity/ clusters/ sheets/ and naked nuclei
#13953
middle Confidence
Subject:
clusters
(Cytological characteristics)
→
is_shown_in
→
Object:
AGCT
(disease)
Original: AGCTs and JGCT#showed#hypercellularity/ clusters/ sheets/ and naked nuclei
#13952
middle Confidence
Subject:
hypercellularity
(Cytological characteristics)
→
is_shown_in
→
Object:
JGCT
(disease)
Original: AGCTs and JGCT#showed#hypercellularity/ clusters/ sheets/ and naked nuclei
#13951
middle Confidence
Subject:
hypercellularity
(Cytological characteristics)
→
is_shown_in
→
Object:
AGCT
(disease)
Original: AGCTs and JGCT#showed#hypercellularity/ clusters/ sheets/ and naked nuclei
#13950
middle Confidence
Subject:
Necrosis
(Pathological characteristics)
→
is_evaluated_in
→
Object:
AGCT
(disease)
Original: Imprints and fluids#were evaluated for#hypercellularity/ Call-Exner bodies/ nuclear grooves/ and necrosis in AGCT
#13949
middle Confidence
Subject:
nuclear_grooves
(Nuclear characteristics)
→
is_evaluated_in
→
Object:
AGCT
(disease)
Original: Imprints and fluids#were evaluated for#hypercellularity/ Call-Exner bodies/ nuclear grooves/ and necrosis in AGCT
#13948
middle Confidence
Subject:
Call-Exner_bodies
(Cell structure characteristics)
→
is_evaluated_in
→
Object:
AGCT
(disease)
Original: Imprints and fluids#were evaluated for#hypercellularity/ Call-Exner bodies/ nuclear grooves/ and necrosis in AGCT
#13947
middle Confidence
Subject:
hypercellularity
(Cytological characteristics)
→
is_evaluated_in
→
Object:
AGCT
(disease)
Original: Imprints and fluids#were evaluated for#hypercellularity/ Call-Exner bodies/ nuclear grooves/ and necrosis in AGCT
#13946
middle Confidence
Subject:
ultrasound-guided_fine_needle_aspiration_cytology
(Imaging diagnostic technology)
→
retrieves_cases_of
→
Object:
HCC
(disease)
Original: Cases diagnosed with HCC#were retrieved from#ultrasound-guided fine needle aspiration cytology
#13940
middle Confidence
Subject:
fine-needle_aspiration
(Diagnostic techniques)
→
diagnoses
→
Object:
recurrent_esthesioneuroblastoma
(Tumor)
Original: Recurrent esthesioneuroblastoma#was diagnosed by#fine-needle aspiration of a midcervical mass
#13913
middle Confidence
Subject:
tumor
(Tumor tissue)
→
expresses
→
Object:
synaptophysin
(Neuroendocrine markers)
Original: tumor#expresses#neuroendocrine markers (chromogranin/ synaptophysin)
#13912
middle Confidence
Subject:
tumor
(Tumor tissue)
→
expresses
→
Object:
Chromogranin
(Neuroendocrine markers)
Original: tumor#expresses#neuroendocrine markers (chromogranin/ synaptophysin)
#13911
middle Confidence
Subject:
inclusion_bodies
(Cellular substructure)
→
are_immunohistochemically_positive_for
→
Object:
vimentin
(Intermediate filament protein)
Original: inclusion bodies#are immunohistochemically positive for#vimentin
#13895
middle Confidence
Subject:
Breast_imagers
(Medical imaging doctor)
→
should_be_aware_of
→
Object:
breast_cancer
(Tumor diseases)
Original: Breast imagers#should be aware of#GCT of the breast as a differential for breast cancer
#13894
middle Confidence
Subject:
Breast_imagers
(Medical imaging doctor)
→
should_be_aware_of
→
Object:
GCT_of_the_breast
(Tumor diseases)
Original: Breast imagers#should be aware of#GCT of the breast as a differential for breast cancer
#13888
middle Confidence
Subject:
atypical_spermatogonia
(Germ cells)
→
were_described_in
→
Object:
testicular_biopsies
(organize)
Original: atypical spermatogonia#were described in#testicular biopsies performed for fertility disturbances
#13859
middle Confidence
Subject:
radiologic_study
(Imaging tests)
→
revealed
→
Object:
large_anterior_mediastinal_mass
(Tumor phenotype)
Original: Radiologic studies#revealed#a large anterior mediastinal mass
#13858
middle Confidence
Subject:
thymic_carcinoma
(Tumor type)
→
shows
→
Object:
rhabdoid_differentiation
(Cell differentiation)
Original: A case of thymic carcinoma#is presented with#rhabdoid differentiation
#13855
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_composed_of
→
Object:
central_nucleolus
(Cell morphology)
Original: NUT carcinoma#is composed of#poorly differentiated sheets of small cells with scant cytoplasm/ round nucleus/ and central nucleolus
#13854
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_composed_of
→
Object:
round_nucleus
(Cell morphology)
Original: NUT carcinoma#is composed of#poorly differentiated sheets of small cells with scant cytoplasm/ round nucleus/ and central nucleolus
#13853
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_composed_of
→
Object:
scant_cytoplasm
(Cell morphology)
Original: NUT carcinoma#is composed of#poorly differentiated sheets of small cells with scant cytoplasm/ round nucleus/ and central nucleolus
#13852
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_composed_of
→
Object:
poorly_differentiated_small_cells
(Cell morphology)
Original: NUT carcinoma#is composed of#poorly differentiated sheets of small cells with scant cytoplasm/ round nucleus/ and central nucleolus
#13846
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
positive_for
→
Object:
epithelial_membrane_antigen
(Membrane Protein)
Original: Tumor cells#were positive for#cytokeratin and epithelial membrane antigen
#13845
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
positive_for
→
Object:
cytokeratin
(Structural proteins)
Original: Tumor cells#were positive for#cytokeratin and epithelial membrane antigen
#13843
middle Confidence
Subject:
IPMC
(Tumor type)
→
exhibits
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: Noninvasive IPMCs#exhibited#clearly defined cytoplasmic boundaries and prominent nucleoli
#13842
middle Confidence
Subject:
IPMC
(Tumor type)
→
exhibits
→
Object:
clearly_defined_cytoplasmic_boundaries
(Cell morphology)
Original: Noninvasive IPMCs#exhibited#clearly defined cytoplasmic boundaries and prominent nucleoli
#13841
middle Confidence
Subject:
tumor_sample
(Tissue samples)
→
diagnosed_as
→
Object:
mucin-producing_tumor
(Tumor type)
Original: Tumor samples from 23 patients#were examined#cytologically for mucin-producing tumors
#13833
middle Confidence
Subject:
Ki-1_lymphoma
(Tumor type)
→
shows
→
Object:
weak_leukocyte_common_antigen_expression
(Protein expression characteristics)
Original: A case of Ki-1 lymphoma#is presented with#weak leukocyte common antigen expression
#13832
middle Confidence
Subject:
endocervical_cell_clusters
(Cell structure)
→
lack
→
Object:
honeycomb_appearance_of_normal_cells
(Cell morphology)
Original: Clusters of endocervical cells#lacked#honeycomb appearance of normal cells
#13831
middle Confidence
Subject:
endocervical_cells
(Cell Type)
→
appear_as
→
Object:
cell_clusters_with_mucin_filled_cytoplasm
(Cell morphology)
Original: Endocervical cells#appeared as#single cells and clusters with mucin-filled cytoplasm
#13830
middle Confidence
Subject:
endocervical_cells
(Cell Type)
→
appear_as
→
Object:
single_cells
(Cell morphology)
Original: Endocervical cells#appeared as#single cells and clusters with mucin-filled cytoplasm
#13826
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
vesicular_nuclei_with_prominent_nucleoli
(Nuclear characteristics)
Original: Tumor cells#showed#granular cytoplasm and vesicular nuclei with prominent nucleoli
#13825
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
granular_cytoplasm
(Cell morphology)
Original: Tumor cells#showed#granular cytoplasm and vesicular nuclei with prominent nucleoli
#13824
middle Confidence
Subject:
Askanazy_cells
(Cell Type)
→
lack
→
Object:
macronucleoli
(Nuclear characteristics)
Original: Macronucleoli#were present in#Hürthle cell tumors but not in Askanazy cells of Hashimoto's thyroiditis
#13823
middle Confidence
Subject:
Hürthle_cells
(Cell Type)
→
contain
→
Object:
macronucleoli
(Nuclear characteristics)
Original: Macronucleoli#were present in#Hürthle cell tumors but not in Askanazy cells of Hashimoto's thyroiditis
#13822
middle Confidence
Subject:
Askanazy_cells
(Cell Type)
→
shows
→
Object:
bland_and_even_nuclear_chromatin
(Nuclear characteristics)
Original: Nuclear chromatin of Askanazy cells#was#bland and even in Hashimoto's thyroiditis
#13821
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
forms
→
Object:
cell_clusters
(Cell morphology)
Original: Hashimoto's thyroiditis#was characterized by#flat sheets and clusters of epithelial cells with oncocytic changes
#13820
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
forms
→
Object:
flat_sheets
(Cell morphology)
Original: Hashimoto's thyroiditis#was characterized by#flat sheets and clusters of epithelial cells with oncocytic changes
#13819
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
shows_morphology_of
→
Object:
oncocytic_change
(Cell morphology)
Original: Hashimoto's thyroiditis#was characterized by#flat sheets and clusters of epithelial cells with oncocytic changes
#13815
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Fine needle aspiration cytology)
→
finds
→
Object:
pilomatrixoma
(Tumor type)
Original: Fine needle aspiration cytology#finds#four cases of pilomatrixoma
#13814
middle Confidence
Subject:
ghost_cells
(Cell Type)
→
help_in
→
Object:
FNA_diagnosis_of_pilomatrixoma
(Diagnostic Process)
Original: Ghost cells#help in#FNA diagnosis of pilomatrixoma
#13809
middle Confidence
Subject:
multinucleated_giant_cells
(Cell subtype)
→
support
→
Object:
cytologic_diagnosis_of_pilomatrixoma
(Diagnosis conclusion)
Original: Ghost cells and multinucleated giant cells#support#cytologic diagnosis of pilomatrixoma
#13808
middle Confidence
Subject:
ghost_cells
(Cell subtype)
→
support
→
Object:
cytologic_diagnosis_of_pilomatrixoma
(Diagnosis conclusion)
Original: Ghost cells and multinucleated giant cells#support#cytologic diagnosis of pilomatrixoma
#13807
middle Confidence
Subject:
statistical_analysis
(Statistical analysis methods)
→
found
→
Object:
significant_cytologic_features
(Cytological characteristics)
Original: Statistical analysis#found#significant cytologic features for low-grade spindle cell lesions
#13806
middle Confidence
Subject:
logistic_regression_analysis
(Statistical analysis methods)
→
identifies
→
Object:
variables_predictive_of_malignant_lesions
(Predictor variables)
Original: Logistic regression analysis#identifies#variables predictive of malignant lesions
#13805
middle Confidence
Subject:
ultrastructural_studies
(Ultrastructural examination)
→
aid_in
→
Object:
classification_of_leukemia
(Disease classification)
Original: Histochemical or ultrastructural studies#aid in#proper classification of leukemia
#13804
middle Confidence
Subject:
histochemical_studies
(Histochemical testing)
→
aid_in
→
Object:
classification_of_leukemia
(Disease classification)
Original: Histochemical or ultrastructural studies#aid in#proper classification of leukemia
#13799
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
contain
→
Object:
small_nucleoli
(Nucleolus)
Original: Tumor cells#were composed of#large cells with abundant slightly eosinophilic vacuolated cytoplasm and ovoid or reniform nuclei with a few small nucleoli
#13798
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
have
→
Object:
ovoid_or_reniform_nuclei
(Nuclear morphology)
Original: Tumor cells#were composed of#large cells with abundant slightly eosinophilic vacuolated cytoplasm and ovoid or reniform nuclei with a few small nucleoli
#13797
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
have
→
Object:
abundant_slightly_eosinophilic_vacuolated_cytoplasm
(Cytoplasmic characteristics)
Original: Tumor cells#were composed of#large cells with abundant slightly eosinophilic vacuolated cytoplasm and ovoid or reniform nuclei with a few small nucleoli
#13796
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_composed_of
→
Object:
large_cells
(Cell characteristics)
Original: Tumor cells#were composed of#large cells with abundant slightly eosinophilic vacuolated cytoplasm and ovoid or reniform nuclei with a few small nucleoli
#13795
middle Confidence
Subject:
cytologic_hallmark
(Cytological signs)
→
is
→
Object:
inconspicuous_nucleoli
(Nucleolus)
Original: cytologic hallmark#is#presence of medium-sized cells with inconspicuous nucleoli
#13794
middle Confidence
Subject:
cytologic_hallmark
(Cytological signs)
→
is
→
Object:
presence_of_medium_sized_cells
(Cell characteristics)
Original: cytologic hallmark#is#presence of medium-sized cells with inconspicuous nucleoli
#13793
middle Confidence
Subject:
atypical_cells
(Abnormal cells)
→
exhibit
→
Object:
multiple_conspicuous_nucleoli
(Nucleolus)
Original: atypical cells#exhibit#multiple conspicuous nucleoli
#13792
middle Confidence
Subject:
atypical_cells
(Abnormal cells)
→
have
→
Object:
coarsely_granular_chromatin
(Chromatin morphology)
Original: atypical cells#contain#a single macronucleolus with coarsely granular chromatin
#13791
middle Confidence
Subject:
cells
(cell)
→
exhibit
→
Object:
anaplasia
(Cellular atypia)
Original: cells#exhibit#prominent nucleoli and anaplasia
#13790
middle Confidence
Subject:
cells
(cell)
→
exhibit
→
Object:
prominent_nucleoli
(Nucleolus)
Original: cells#exhibit#prominent nucleoli and anaplasia
#13789
middle Confidence
Subject:
nuclei
(Nucleus)
→
lack
→
Object:
nucleoli
(Nucleolus)
Original: nuclei#are#oval with clumped chromatin and absent nucleoli in most cells
#13788
middle Confidence
Subject:
nuclei
(Nucleus)
→
have
→
Object:
clumped_chromatin
(Chromatin morphology)
Original: nuclei#are#oval with clumped chromatin and absent nucleoli in most cells
#13787
middle Confidence
Subject:
nuclei
(Nucleus)
→
are
→
Object:
oval_shape
(Nuclear morphology)
Original: nuclei#are#oval with clumped chromatin and absent nucleoli in most cells
#13760
middle Confidence
Subject:
large_histiocytes
(Histiocytes)
→
resemble
→
Object:
Hodgkin_cells
(Cell Type)
Original: Lymph node biopsy#revealed#large histiocytes resembling Hodgkin cells with round or stellate shape/ abundant cytoplasm/ and distinct nucleoli
#13759
middle Confidence
Subject:
dyskeratotic_cells
(Cell morphology)
→
is_associated_with
→
Object:
invasive_neoplasia
(Tumor type)
Original: Increased nuclear/cytoplasmic ratio and dyskeratotic cells#are associated with#intraepithelial or invasive neoplasia
#13758
middle Confidence
Subject:
dyskeratotic_cells
(Cell morphology)
→
is_associated_with
→
Object:
intraepithelial_neoplasia
(Tumor type)
Original: Increased nuclear/cytoplasmic ratio and dyskeratotic cells#are associated with#intraepithelial or invasive neoplasia
#13757
middle Confidence
Subject:
increased_nuclear_cytoplasmic_ratio
(Cell morphology)
→
is_associated_with
→
Object:
invasive_neoplasia
(Tumor type)
Original: Increased nuclear/cytoplasmic ratio and dyskeratotic cells#are associated with#intraepithelial or invasive neoplasia
#13756
middle Confidence
Subject:
increased_nuclear_cytoplasmic_ratio
(Cell morphology)
→
is_associated_with
→
Object:
intraepithelial_neoplasia
(Tumor type)
Original: Increased nuclear/cytoplasmic ratio and dyskeratotic cells#are associated with#intraepithelial or invasive neoplasia
#13749
middle Confidence
Subject:
abdominal_sonography
(Imaging tests)
→
revealed
→
Object:
pleural_fluid
(Imaging phenotype)
Original: Abdominal sonography and CT scan#revealed#hepatosplenomegaly/ intrahepatic mass/ celiac lymph node enlargement/ ascites/ and pleural fluid
#13748
middle Confidence
Subject:
abdominal_sonography
(Imaging tests)
→
revealed
→
Object:
ascites
(Imaging phenotype)
Original: Abdominal sonography and CT scan#revealed#hepatosplenomegaly/ intrahepatic mass/ celiac lymph node enlargement/ ascites/ and pleural fluid
#13747
middle Confidence
Subject:
abdominal_sonography
(Imaging tests)
→
revealed
→
Object:
celiac_lymph_node_enlargement
(Imaging phenotype)
Original: Abdominal sonography and CT scan#revealed#hepatosplenomegaly/ intrahepatic mass/ celiac lymph node enlargement/ ascites/ and pleural fluid
#13746
middle Confidence
Subject:
abdominal_sonography
(Imaging tests)
→
revealed
→
Object:
intrahepatic_mass
(Imaging phenotype)
Original: Abdominal sonography and CT scan#revealed#hepatosplenomegaly/ intrahepatic mass/ celiac lymph node enlargement/ ascites/ and pleural fluid
#13745
middle Confidence
Subject:
abdominal_sonography
(Imaging tests)
→
revealed
→
Object:
hepatosplenomegaly
(Imaging phenotype)
Original: Abdominal sonography and CT scan#revealed#hepatosplenomegaly/ intrahepatic mass/ celiac lymph node enlargement/ ascites/ and pleural fluid
#13741
middle Confidence
Subject:
Paget's_cells
(Tumor cells)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: Paget's cells#are characterized by#large round cells with abundant pale or granular/dusty cytoplasm/ pleomorphic vesicular nuclei/ and prominent nucleoli
#13740
middle Confidence
Subject:
Paget's_cells
(Tumor cells)
→
are_characterized_by
→
Object:
pleomorphic_vesicular_nuclei
(Nuclear characteristics)
Original: Paget's cells#are characterized by#large round cells with abundant pale or granular/dusty cytoplasm/ pleomorphic vesicular nuclei/ and prominent nucleoli
#13739
middle Confidence
Subject:
Paget's_cells
(Tumor cells)
→
are_characterized_by
→
Object:
large_round_cells_with_abundant_pale_or_granular_cytoplasm
(Cell morphology)
Original: Paget's cells#are characterized by#large round cells with abundant pale or granular/dusty cytoplasm/ pleomorphic vesicular nuclei/ and prominent nucleoli
#13718
middle Confidence
Subject:
CD10
(Protease)
→
revealed
→
Object:
cytoplasmic_positivity_in_these_cells
(Protein expression characteristics)
Original: CD10 immunostaining#revealed#cytoplasmic positivity in these cells
#13710
middle Confidence
Subject:
biopsy specimens
(Tissue samples)
→
show
→
Object:
transitional forms with type B features
(Histological type)
Original: biopsy specimens#showed#transitional forms with histological features of type A and type B
#13709
middle Confidence
Subject:
biopsy specimens
(Tissue samples)
→
show
→
Object:
transitional forms with type A features
(Histological type)
Original: biopsy specimens#showed#transitional forms with histological features of type A and type B
#13708
middle Confidence
Subject:
biopsies
(Tissue samples)
→
reveal
→
Object:
type B histology
(Histological type)
Original: biopsies#revealed#two histological types (type A and type B)
#13707
middle Confidence
Subject:
biopsies
(Tissue samples)
→
reveal
→
Object:
type A histology
(Histological type)
Original: biopsies#revealed#two histological types (type A and type B)
#13706
middle Confidence
Subject:
blastoid cells
(Tumor cells)
→
exhibit
→
Object:
IgM-positive phenotype
(Surface markers)
Original: blasts#exhibited#a CD20-/ CD19-/ IgM-positive phenotype
#13705
middle Confidence
Subject:
blastoid cells
(Tumor cells)
→
exhibit
→
Object:
CD19-positive phenotype
(Surface markers)
Original: blasts#exhibited#a CD20-/ CD19-/ IgM-positive phenotype
#13704
middle Confidence
Subject:
blastoid cells
(Tumor cells)
→
exhibit
→
Object:
CD20-positive phenotype
(Surface markers)
Original: blasts#exhibited#a CD20-/ CD19-/ IgM-positive phenotype
#13690
middle Confidence
Subject:
cytologic_differential_diagnosis
(Diagnostic Process)
→
gives
→
Object:
adenocarcinoma
(Tumor type)
Original: Cytologic differential diagnosis#gives#clear cell carcinoma/ microglandular hyperplasia/ diffuse laminar glandular hyperplasia/ tubal metaplasia/ and adenocarcinoma
#13689
middle Confidence
Subject:
cytologic_differential_diagnosis
(Diagnostic Process)
→
gives
→
Object:
clear_cell_carcinoma
(Tumor type)
Original: Cytologic differential diagnosis#gives#clear cell carcinoma/ microglandular hyperplasia/ diffuse laminar glandular hyperplasia/ tubal metaplasia/ and adenocarcinoma
#13687
middle Confidence
Subject:
apocrine_cells
(Glandular cells)
→
may_represent
→
Object:
apocrine_carcinoma
(Glandular cancer)
Original: atypical apocrine adenosis#may represent#in situ apocrine carcinomas
#13686
middle Confidence
Subject:
atypical_apocrine_adenosis
(Abnormal gland structure)
→
may_represent
→
Object:
in_situ_apocrine_carcinomas
(Glandular cancer)
Original: atypical apocrine adenosis#may represent#in situ apocrine carcinomas
#13685
middle Confidence
Subject:
epithelioid_cells
(Epithelioid cells)
→
are_characterized_by
→
Object:
eosinophilic_cytoplasm
(Cytoplasmic morphology)
Original: epithelioid cells#are characterized by#vesicular nuclei/ prominent nucleoli/ and eosinophilic cytoplasm
#13684
middle Confidence
Subject:
epithelioid_cells
(Epithelioid cells)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear morphology)
Original: epithelioid cells#are characterized by#vesicular nuclei/ prominent nucleoli/ and eosinophilic cytoplasm
#13683
middle Confidence
Subject:
epithelioid_cells
(Epithelioid cells)
→
are_characterized_by
→
Object:
vesicular_nuclei
(Nuclear morphology)
Original: epithelioid cells#are characterized by#vesicular nuclei/ prominent nucleoli/ and eosinophilic cytoplasm
#13641
middle Confidence
Subject:
cranial_fasciitis
(disease)
→
presents_as
→
Object:
rapidly_expanding_painless_nodule
(Clinical symptoms)
Original: clinical presentation of CF#is#rapidly expanding/ painless nodule
#13637
middle Confidence
Subject:
histologic_features
(Histological characteristics)
→
are_essentially_the_same_as
→
Object:
original_sarcoma_monophasic_spindle_cell_variant
(Tumor tissue morphology)
Original: histologic features#are essentially the same as#original sarcoma corresponding to monophasic spindle cell variant
#13627
middle Confidence
Subject:
bone_marrow_biopsy
(Histological examination)
→
performed_to_obtain
→
Object:
definite_diagnosis
(Diagnosis conclusion)
Original: excisional lymph node biopsy and bone marrow biopsy#are performed to obtain#a definite diagnosis
#13626
middle Confidence
Subject:
excisional_lymph_node_biopsy
(Histological examination)
→
performed_to_obtain
→
Object:
definite_diagnosis
(Diagnosis conclusion)
Original: excisional lymph node biopsy and bone marrow biopsy#are performed to obtain#a definite diagnosis
#13616
middle Confidence
Subject:
cytological_recognition
(Cytological evaluation)
→
emphasizes
→
Object:
inclusion_of_BPDCN-specific_immunophenotypic_markers
(Diagnostic markers)
Original: Clinical suspicion and cytological recognition#are emphasized for#including BPDCN-specific immunophenotypic markers
#13615
middle Confidence
Subject:
clinical_suspicion
(Clinical evaluation)
→
emphasizes
→
Object:
inclusion_of_BPDCN-specific_immunophenotypic_markers
(Diagnostic markers)
Original: Clinical suspicion and cytological recognition#are emphasized for#including BPDCN-specific immunophenotypic markers
#13614
middle Confidence
Subject:
BPDCN
(disease)
→
is_identified_in
→
Object:
cerebrospinal_fluid
(body fluid)
Original: BPDCN#is identified in#cerebrospinal fluid with cytomorphological and immunophenotypic features
#13613
middle Confidence
Subject:
Myeloperoxidase
(Enzymes)
→
is_expressed_in
→
Object:
LMA-MO
(disease)
Original: Myeloperoxidase#is expressed in#three cases of LMA-MO
#13612
middle Confidence
Subject:
lymphoid_antigens
(Cell surface antigens)
→
is_not_expressed_in
→
Object:
LMA-MO
(disease)
Original: Immunophenotyping#shows#expression of CD13 and CD33/ negative for lymphoid antigens
#13611
middle Confidence
Subject:
CD33
(Cell surface antigens)
→
is_expressed_in
→
Object:
LMA-MO
(disease)
Original: Immunophenotyping#shows#expression of CD13 and CD33/ negative for lymphoid antigens
#13610
middle Confidence
Subject:
CD13
(Cell surface antigens)
→
is_expressed_in
→
Object:
LMA-MO
(disease)
Original: Immunophenotyping#shows#expression of CD13 and CD33/ negative for lymphoid antigens
#13602
middle Confidence
Subject:
findings
(Histological findings)
→
favor
→
Object:
invasive_carcinoma
(Malignant tumors)
Original: findings#favor#benign process over invasive carcinoma
#13601
middle Confidence
Subject:
findings
(Histological findings)
→
favor
→
Object:
benign_process
(Benign process)
Original: findings#favor#benign process over invasive carcinoma
#13600
middle Confidence
Subject:
findings
(Histological findings)
→
include
→
Object:
hyperchromatic_raisinoid_nucleoli
(Histological characteristics)
Original: findings#include#intraluminal necrotic cellular debris and hyperchromatic raisinoid nucleoli
#13599
middle Confidence
Subject:
findings
(Histological findings)
→
include
→
Object:
intraluminal_necrotic_cellular_debris
(Histological characteristics)
Original: findings#include#intraluminal necrotic cellular debris and hyperchromatic raisinoid nucleoli
#13597
middle Confidence
Subject:
prominent_nucleoli
(Cell morphology)
→
is_associated_with
→
Object:
suspicion_of_malignancy_in_fibroadenomas
(Diagnostic categories)
Original: Cellular dyscohesion and prominent nucleoli#are associated with#suspicion of malignancy in fibroadenomas
#13596
middle Confidence
Subject:
cellular_dyscohesion
(Cell biological characteristics)
→
is_associated_with
→
Object:
suspicion_of_malignancy_in_fibroadenomas
(Diagnostic categories)
Original: Cellular dyscohesion and prominent nucleoli#are associated with#suspicion of malignancy in fibroadenomas
#13595
middle Confidence
Subject:
Epithelial_atypia
(Pathological conditions)
→
is_distinguished_from
→
Object:
superficial_cancer
(Pathological conditions)
Original: Epithelial atypia#is distinguished from#superficial cancer by epithelial maturation/ preserved nuclear/cytoplasmic ratio/ and smooth nuclear contours
#13594
middle Confidence
Subject:
Polyhedral_epithelial_cells
(Epithelial cells)
→
have
→
Object:
prominent_nucleoli
(Prominent nucleoli)
Original: Tumor cells#show#clusters of polyhedral epithelial cells with cyanophilic vacuolated cytoplasm/ hyperchromatic nuclei/ and prominent nucleoli
#13593
middle Confidence
Subject:
Polyhedral_epithelial_cells
(Epithelial cells)
→
have
→
Object:
hyperchromatic_nuclei
(Darkly stained nuclei)
Original: Tumor cells#show#clusters of polyhedral epithelial cells with cyanophilic vacuolated cytoplasm/ hyperchromatic nuclei/ and prominent nucleoli
#13592
middle Confidence
Subject:
Polyhedral_epithelial_cells
(Epithelial cells)
→
have
→
Object:
cyanophilic_vacuolated_cytoplasm
(Cyanophilic vacuolated cytoplasm)
Original: Tumor cells#show#clusters of polyhedral epithelial cells with cyanophilic vacuolated cytoplasm/ hyperchromatic nuclei/ and prominent nucleoli
#13591
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
clusters_of_polyhedral_epithelial_cells
(Polygonal epithelial cell clusters)
Original: Tumor cells#show#clusters of polyhedral epithelial cells with cyanophilic vacuolated cytoplasm/ hyperchromatic nuclei/ and prominent nucleoli
#13583
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
shows
→
Object:
fine_chromatin
(Fine granular chromatin)
Original: FNAC of tumor cells#shows#eosinophilic granular cytoplasm/ ill-defined cell borders/ round to oval nuclei/ solitary round eosinophilic nucleoli/ and fine chromatin
#13582
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
shows
→
Object:
solitary_round_eosinophilic_nucleoli
(Isolated round eosinophilic nucleoli)
Original: FNAC of tumor cells#shows#eosinophilic granular cytoplasm/ ill-defined cell borders/ round to oval nuclei/ solitary round eosinophilic nucleoli/ and fine chromatin
#13581
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
shows
→
Object:
round_to_oval_nuclei
(Round to oval nuclei)
Original: FNAC of tumor cells#shows#eosinophilic granular cytoplasm/ ill-defined cell borders/ round to oval nuclei/ solitary round eosinophilic nucleoli/ and fine chromatin
#13580
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
shows
→
Object:
ill_defined_cell_borders
(Unclear cell boundaries)
Original: FNAC of tumor cells#shows#eosinophilic granular cytoplasm/ ill-defined cell borders/ round to oval nuclei/ solitary round eosinophilic nucleoli/ and fine chromatin
#13579
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
shows
→
Object:
eosinophilic_granular_cytoplasm
(Eosinophilic granular cytoplasm)
Original: FNAC of tumor cells#shows#eosinophilic granular cytoplasm/ ill-defined cell borders/ round to oval nuclei/ solitary round eosinophilic nucleoli/ and fine chromatin
#13575
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
displays
→
Object:
rhabdoid_morphology
(Rhabdoid morphology)
Original: Tumor cells#display#moderate to marked nuclear pleomorphism with prominent nucleoli/ eosinophilic to vacuolated cytoplasm/ rhabdoid morphology/ interspersed mitotic figures/ focal necrosis/ and inflammatory cells
#13574
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
displays
→
Object:
vacuolated_cytoplasm
(Vacuolated cytoplasm)
Original: Tumor cells#display#moderate to marked nuclear pleomorphism with prominent nucleoli/ eosinophilic to vacuolated cytoplasm/ rhabdoid morphology/ interspersed mitotic figures/ focal necrosis/ and inflammatory cells
#13573
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
displays
→
Object:
eosinophilic_cytoplasm
(Eosinophilic cytoplasm)
Original: Tumor cells#display#moderate to marked nuclear pleomorphism with prominent nucleoli/ eosinophilic to vacuolated cytoplasm/ rhabdoid morphology/ interspersed mitotic figures/ focal necrosis/ and inflammatory cells
#13572
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
displays
→
Object:
prominent_nucleoli
(Prominent nucleoli)
Original: Tumor cells#display#moderate to marked nuclear pleomorphism with prominent nucleoli/ eosinophilic to vacuolated cytoplasm/ rhabdoid morphology/ interspersed mitotic figures/ focal necrosis/ and inflammatory cells
#13571
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
displays
→
Object:
nuclear_pleomorphism
(Nuclear pleomorphism)
Original: Tumor cells#display#moderate to marked nuclear pleomorphism with prominent nucleoli/ eosinophilic to vacuolated cytoplasm/ rhabdoid morphology/ interspersed mitotic figures/ focal necrosis/ and inflammatory cells
#13565
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Cytology)
→
reviewed
→
Object:
medical_carcinoma_of_thyroid
(Tumor type)
Original: fine needle aspiration cytology#reviewed#medullary carcinomas of thyroid
#13564
middle Confidence
Subject:
endometrial_currettings
(Tissue samples)
→
showed
→
Object:
malignant_non-Hodgkin's_lymphoma_diffuse_large_cell_type
(Tumor phenotype)
Original: endometrial currettings#showed#malignant non-Hodgkin's lymphoma/ diffuse/ large cell type
#13562
middle Confidence
Subject:
MTSCC-K
(Tumor type)
→
is_described_as
→
Object:
rare_low-grade_malignancy
(Disease classification)
Original: MTSCC-K#is described as#a rare low-grade malignancy with unique histological and immunohistochemical characteristics
#13561
middle Confidence
Subject:
recognition_of_clinicopathological_features
(Diagnostic Process)
→
is_important_to
→
Object:
improve_clinical_and_differential_diagnosis
(Diagnostic Process)
Original: recognition of clinicopathological features of MTSCC-K#is important to#improve its clinical and differential diagnosis
#13560
middle Confidence
Subject:
infiltrates
(Immune cell infiltration)
→
are_expression_of
→
Object:
stage_4_disease_of_extracutaneous_B-cell_lymphoma
(Disease Stage)
Original: infiltrates#are an expression of#stage 4 disease of extracutaneous B-cell lymphoma
#13559
middle Confidence
Subject:
SPTCL
(disease)
→
is_characterized_by
→
Object:
subcutaneous_infiltration_with_benign_macrophages
(Cell infiltration)
Original: SPTCL#is characterized by#subcutaneous infiltration with pleomorphic T-cells and benign macrophages
#13558
middle Confidence
Subject:
SPTCL
(disease)
→
is_characterized_by
→
Object:
subcutaneous_infiltration_with_pleomorphic_T-cells
(Cell infiltration)
Original: SPTCL#is characterized by#subcutaneous infiltration with pleomorphic T-cells and benign macrophages
#13557
middle Confidence
Subject:
Right_thyroidectomy
(Surgical Procedure)
→
shows
→
Object:
histologic_features_diagnostic_for_SMECE
(Histological characteristics)
Original: Right thyroidectomy#shows#histologic features diagnostic for SMECE
#13555
middle Confidence
Subject:
steroidogenic_activity
(Cell Function)
→
can_be_assessed_using
→
Object:
ultrastructural_picture_of_mitochondria
(Cellular substructure)
Original: Steroidogenic activity#can be assessed using#ultrastructural picture of agranular endoplasmic reticulum and mitochondria
#13554
middle Confidence
Subject:
steroidogenic_activity
(Cell Function)
→
can_be_assessed_using
→
Object:
ultrastructural_picture_of_agranular_endoplasmic_reticulum
(Cellular substructure)
Original: Steroidogenic activity#can be assessed using#ultrastructural picture of agranular endoplasmic reticulum and mitochondria
#13553
middle Confidence
Subject:
histological_examination
(Histological examination)
→
diagnosed
→
Object:
bladder_cancer
(disease)
Original: Histological examination#diagnosed#LG-UCs from bladder cancer
#13552
middle Confidence
Subject:
histological_examination
(Histological examination)
→
diagnosed
→
Object:
LG-UCs
(Tumor type)
Original: Histological examination#diagnosed#LG-UCs from bladder cancer
#13511
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
describe
→
Object:
FNA_breast_lesion_with_adenoid_cystic_carcinoma_histology
(Histological characteristics)
Original: cytologic findings#describe#FNA breast lesion with adenoid cystic carcinoma histology
#13480
middle Confidence
Subject:
vascular_structures_in_smears
(Morphological characteristics)
→
suggested
→
Object:
liposarcoma
(Tumor type)
Original: Vascular structures in smears#suggested#angiosarcoma or liposarcoma
#13479
middle Confidence
Subject:
vascular_structures_in_smears
(Morphological characteristics)
→
suggested
→
Object:
angiosarcoma
(Tumor type)
Original: Vascular structures in smears#suggested#angiosarcoma or liposarcoma
#13461
middle Confidence
Subject:
MRI_of_brain
(Imaging tests)
→
revealed
→
Object:
hyperdense_enhancing_mass_in_left_frontal_parietal_lobe
(Imaging findings)
Original: MRI of the brain#revealed#a well-defined hyperdense and enhancing mass in the left frontal-parietal lobe
#13431
middle Confidence
Subject:
CD99
(Cell surface antigens)
→
is_observed_in
→
Object:
malignancy
(Disease phenotype)
Original: Positive rates for myeloperoxidase/ CD43/ CD34/ CD117/ CD68/ Lysozyme/ CD99/ and naphthol AS-D chloroacetate esterase#were observed in#malignancy
#13430
middle Confidence
Subject:
Lysozyme
(Enzymes)
→
is_observed_in
→
Object:
malignancy
(Disease phenotype)
Original: Positive rates for myeloperoxidase/ CD43/ CD34/ CD117/ CD68/ Lysozyme/ CD99/ and naphthol AS-D chloroacetate esterase#were observed in#malignancy
#13429
middle Confidence
Subject:
CD68
(Lysosome-associated proteins)
→
is_observed_in
→
Object:
malignancy
(Disease phenotype)
Original: Positive rates for myeloperoxidase/ CD43/ CD34/ CD117/ CD68/ Lysozyme/ CD99/ and naphthol AS-D chloroacetate esterase#were observed in#malignancy
#13428
middle Confidence
Subject:
CD117
(Receptor tyrosine kinases)
→
is_observed_in
→
Object:
malignancy
(Disease phenotype)
Original: Positive rates for myeloperoxidase/ CD43/ CD34/ CD117/ CD68/ Lysozyme/ CD99/ and naphthol AS-D chloroacetate esterase#were observed in#malignancy
#13427
middle Confidence
Subject:
CD34
(Cell surface antigens)
→
is_observed_in
→
Object:
malignancy
(Disease phenotype)
Original: Positive rates for myeloperoxidase/ CD43/ CD34/ CD117/ CD68/ Lysozyme/ CD99/ and naphthol AS-D chloroacetate esterase#were observed in#malignancy
#13426
middle Confidence
Subject:
CD43
(Membrane Protein)
→
is_observed_in
→
Object:
malignancy
(Disease phenotype)
Original: Positive rates for myeloperoxidase/ CD43/ CD34/ CD117/ CD68/ Lysozyme/ CD99/ and naphthol AS-D chloroacetate esterase#were observed in#malignancy
#13425
middle Confidence
Subject:
myeloperoxidase
(Enzymes)
→
is_observed_in
→
Object:
malignancy
(Disease phenotype)
Original: Positive rates for myeloperoxidase/ CD43/ CD34/ CD117/ CD68/ Lysozyme/ CD99/ and naphthol AS-D chloroacetate esterase#were observed in#malignancy
#13364
middle Confidence
Subject:
IDC
(Disease name)
→
is_similar_to
→
Object:
ductal_carcinoma_in_situ_of_the_breast
(Disease name)
Original: IDC#is similar to#ductal carcinoma in-situ of the breast
#13359
middle Confidence
Subject:
CD133
(Cell surface markers)
→
positively_identifies
→
Object:
Stem_cells
(Stem Cells)
Original: Staining for CD133#positively identified#stem cells in benign prostatic hyperplasia/ benign prostate/ and prostate cancer cells
#13358
middle Confidence
Subject:
Lymphocytic_infiltration_in_stroma
(Organizational characteristics)
→
is_characteristic_of
→
Object:
this_tumor
(Tumor type)
Original: Lymphocytic infiltration in the stroma#is one of#the most characteristic features of this tumor
#13356
middle Confidence
Subject:
Nucleoli
(Nuclear structure)
→
are_not_prominent_in
→
Object:
Fuhrman_grade_1_or_2
(Tumor grade)
Original: Nucleoli#were not#prominent (Fuhrman grade 1 or 2)
#13332
middle Confidence
Subject:
Adenocarcinoma_cells
(Tumor cells)
→
exhibit
→
Object:
conspicuous_nucleoli
(Nuclear structure)
Original: Cells of induced adenocarcinomas#exhibited#conspicuous nucleoli
#13331
middle Confidence
Subject:
Adenocarcinoma_cells
(Tumor cells)
→
exhibit
→
Object:
large_irregular_nuclei_with_heavily_marginated_chromatin
(Nuclear structure)
Original: Cells of induced adenocarcinomas#exhibited#large irregular nuclei with heavily marginated chromatin
#13330
middle Confidence
Subject:
Adenocarcinoma_cells
(Tumor cells)
→
exhibit
→
Object:
large_nuclear_to_cytoplasmic_ratio
(Cell morphology)
Original: Cells of induced adenocarcinomas#exhibited#large nuclear to cytoplasmic ratio
#13329
middle Confidence
Subject:
Follicular_cells
(Tumor cells)
→
display
→
Object:
nuclear_features_of_papillary_thyroid_carcinoma
(Nuclear phenotype)
Original: Scattered follicles#were detected with#nuclear features of papillary thyroid carcinoma
#13321
middle Confidence
Subject:
Tumor
(Disease phenotype)
→
is_distinguished_from
→
Object:
mesenchymal_lesions
(Organization Type)
Original: Tumor#is distinguished from#reactive or neoplastic mesenchymal lesions
#13316
middle Confidence
Subject:
ASC-H_cases
(Case)
→
showed
→
Object:
CIN1+
(Pathological grading)
Original: 22 ASC-H cases#showed#CIN1+
#13315
middle Confidence
Subject:
immunohistochemical_studies
(Detection Methods)
→
reflect
→
Object:
ultrastructural_findings
(Cell ultrastructure)
Original: Immunohistochemical studies#reflected#ultrastructural findings
#13314
middle Confidence
Subject:
thyroid_pathology
(Pathological process)
→
requires
→
Object:
thoughtful_investigation_for_accurate_diagnosis
(Diagnostic Process)
Original: Thyroid pathology#requires#thoughtful investigation for accurate diagnosis
#13313
middle Confidence
Subject:
oncocytic_change
(Cell morphology)
→
occurs_in
→
Object:
malignant_thyroid_tumors
(disease)
Original: Oncocytic change#occurs in#nontumorous thyroid disorders/ benign and malignant thyroid tumors
#13312
middle Confidence
Subject:
oncocytic_change
(Cell morphology)
→
occurs_in
→
Object:
benign_thyroid_tumors
(disease)
Original: Oncocytic change#occurs in#nontumorous thyroid disorders/ benign and malignant thyroid tumors
#13311
middle Confidence
Subject:
oncocytic_change
(Cell morphology)
→
occurs_in
→
Object:
nontumorous_thyroid_disorders
(disease)
Original: Oncocytic change#occurs in#nontumorous thyroid disorders/ benign and malignant thyroid tumors
#13258
middle Confidence
Subject:
Papanicolaou-stained_cervicovaginal_smears
(Tissue samples)
→
are_correlated_with
→
Object:
tissue_sections_of_endocervical_curettage
(Tissue samples)
Original: Papanicolaou-stained cervicovaginal smears#are correlated with#tissue sections of endocervical curettage
#13250
middle Confidence
Subject:
vimentin
(Intermediate filament protein)
→
shows_strong_immunoreactivity
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#show#strong immunoreactivity for vimentin
#13249
middle Confidence
Subject:
presence_of_two_cell_populations_with_moderate_pleomorphism
(Cell morphology)
→
differentiations
→
Object:
basal_cell_adenocarcinoma
(Adenoid basal cell carcinoma)
Original: Basal cell adenocarcinoma#was differentiated by#presence of two cell populations with moderate pleomorphism
#13248
middle Confidence
Subject:
polymorphic_naked_nuclei_with_prominent_nucleoli
(Nuclear morphology)
→
indicates
→
Object:
recurrence_of_adenocarcinoma
(Adenocarcinoma recurrence)
Original: Recurrence of adenocarcinoma#was indicated by#polymorphic naked nuclei with prominent nucleoli
#13238
middle Confidence
Subject:
FNA_smears
(Cytology)
→
revealed
→
Object:
isolated_cells_with_acinus_pattern
(Tumor cells)
Original: FNA smears#revealed#small tumor cells in cohesive groups and isolated cells with rosette or acinus pattern
#13237
middle Confidence
Subject:
FNA_smears
(Cytology)
→
revealed
→
Object:
isolated_cells_with_rosette_pattern
(Tumor cells)
Original: FNA smears#revealed#small tumor cells in cohesive groups and isolated cells with rosette or acinus pattern
#13236
middle Confidence
Subject:
FNA_smears
(Cytology)
→
revealed
→
Object:
small_tumor_cells_in_cohesive_groups
(Tumor cells)
Original: FNA smears#revealed#small tumor cells in cohesive groups and isolated cells with rosette or acinus pattern
#13233
middle Confidence
Subject:
cytological_diagnosis
(Diagnosis)
→
requires
→
Object:
SMA_expression
(Protein expression)
Original: cytological diagnosis of EMC#requires#definite expression of SMA
#13232
middle Confidence
Subject:
biopsy
(Tissue biopsy)
→
revealed
→
Object:
features_consistent_with_metastatic_eccrine_porocarcinoma
(Pathological diagnostic features)
Original: biopsy#revealed#features consistent with metastatic eccrine porocarcinoma
#13231
middle Confidence
Subject:
other_markers
(Molecular markers)
→
rule_out
→
Object:
morphologically_similar_neoplasms
(Tumor type)
Original: Other markers#ruled out#morphologically similar neoplasms
#13230
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
identify
→
Object:
angiosarcoma
(Tumor type)
Original: Cytologic features#identified#the neoplasm as an angiosarcoma
#13229
middle Confidence
Subject:
cytomorphologic_features
(Cell morphological characteristics)
→
are_useful_in
→
Object:
distinguishing_recurrent_carcinoma
(Tumor Diagnosis Process)
Original: Cytomorphologic features and cell block immunohistochemistry#were useful in#distinguishing recurrent carcinoma
#13196
middle Confidence
Subject:
FISH_techniques
(Molecular detection technology)
→
showed_no_rearrangement_of
→
Object:
EWSR1
(Protein coding genes)
Original: FISH techniques#showed no rearrangement of#NTRK1 or EWSR1
#13195
middle Confidence
Subject:
FISH_techniques
(Molecular detection technology)
→
showed_no_rearrangement_of
→
Object:
NTRK1
(Protein coding genes)
Original: FISH techniques#showed no rearrangement of#NTRK1 or EWSR1
#13193
middle Confidence
Subject:
FNAB_of_mass
(Cytology samples)
→
showed
→
Object:
hypercellular_smear_with_cohesive_branching_clusters_of_spindle_cells
(Cell morphology)
Original: FNAB of the mass#showed#a hypercellular smear with cohesive/ branching clusters of spindle cells
#13192
middle Confidence
Subject:
smears
(Cytology samples)
→
showed
→
Object:
giant_cells_with_osteoclastic-type_multinucleated_giant_cells
(Cell Type)
Original: smears#showed#giant cells with osteoclastic-type multinucleated giant cells
#13191
middle Confidence
Subject:
Immunohistochemical_stains
(Immunohistochemistry)
→
showed
→
Object:
biliary_phenotype
(Phenotypic characteristics)
Original: immunohistochemical stains#showed#a biliary phenotype (positive for biliary cytokeratins/ negative for alpha-fetoprotein)
#13188
middle Confidence
Subject:
large_nuclei
(Nuclear morphology)
→
were_observed_in
→
Object:
adrenocortical_neoplasms
(Tumor type)
Original: large nuclei#were observed predominantly in#adrenocortical neoplasms
#13135
middle Confidence
Subject:
MASC
(Tumor)
→
can_be_mistaken_for
→
Object:
Papillary_thyroid_carcinoma
(Tumor)
Original: MASC#can be mistaken for#papillary thyroid carcinoma
#13134
middle Confidence
Subject:
cohesive_groups_of_tumor_cells
(Cell morphology)
→
are_observed_in
→
Object:
Tumor_cells
(Tumor cells)
Original: Squash preparations#reveal#cohesive groups of tumor cells
#13133
middle Confidence
Subject:
Squash preparations
(Cytology samples)
→
reveal
→
Object:
cohesive_groups_of_tumor_cells
(Cell morphology)
Original: Squash preparations#reveal#cohesive groups of tumor cells
#13121
middle Confidence
Subject:
small_cell_anaplastic_neoplasms
(disease)
→
present
→
Object:
diagnostic_challenges_in_pathology
(Clinical diagnostic features)
Original: small cell anaplastic neoplasms#present#diagnostic challenges in pathology
#13119
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic techniques)
→
is_used_for
→
Object:
undifferentiated_sarcoma_of_the_liver
(Disease Type)
Original: Fine needle aspiration cytology#is used for#undifferentiated sarcoma of the liver
#13118
middle Confidence
Subject:
biphasic_synovial_sarcoma
(Tumor type)
→
is_characterized_by
→
Object:
myoepithelial_features
(Tissue phenotype)
Original: Biphasic synovial sarcoma#is characterized by#myoepithelial features
#13113
middle Confidence
Subject:
differential_diagnosis_with_other_chronic_lymphoproliferative_disorders
(Diagnostic Process)
→
is_based_on
→
Object:
immunocytomorphologic_criteria
(Cellular immune morphology standard)
Original: differential diagnosis with other chronic lymphoproliferative disorders#is based on#clinical and immunocytomorphologic criteria
#13112
middle Confidence
Subject:
differential_diagnosis_with_other_chronic_lymphoproliferative_disorders
(Diagnostic Process)
→
is_based_on
→
Object:
clinical_criteria
(Clinical diagnostic criteria)
Original: differential diagnosis with other chronic lymphoproliferative disorders#is based on#clinical and immunocytomorphologic criteria
#13109
middle Confidence
Subject:
cytological_features_of_CAFs
(Tumor cell morphology)
→
were_evaluated_in
→
Object:
pancreatic_duct_brushing_cytology
(Cytology)
Original: cytological features of CAFs#were evaluated in#pancreatic duct brushing cytology
#13108
middle Confidence
Subject:
cytologic_smears
(Cytology specimens)
→
revealed
→
Object:
atypical_round_to_polygonal_cells
(Tumor cell morphology)
Original: cytologic smears#revealed#numerous atypical round-to-polygonal cells
#13074
middle Confidence
Subject:
effusion_cytology
(Cytological techniques)
→
analyzes
→
Object:
renal_cell_carcinoma
(Tumor)
Original: effusion cytology#analyzes#renal cell carcinoma
#13073
middle Confidence
Subject:
metastatic_lung_adenocarcinoma
(Tumor)
→
has
→
Object:
distinct_cytomorphologic_findings_in_urine
(Cell morphology)
Original: metastatic lung adenocarcinoma#has#distinct cytomorphologic findings in urine
#13067
middle Confidence
Subject:
cytologic_smears_of_metastatic_adenocarcinomas
(Cytology specimens)
→
were_studied_for
→
Object:
morphologic_parameters_to_suggest_primary_sites
(Morphological parameters)
Original: Cytologic smears of metastatic adenocarcinomas#were studied for#morphologic parameters to suggest primary sites
#13063
middle Confidence
Subject:
Rapid onsite staining
(Dyeing technology)
→
helps_to_diagnose
→
Object:
rare cases of salivary gland tumor
(Disease Type)
Original: Rapid onsite staining and cytology#help to diagnose#rare cases of subcutaneous tumor in the absence of primary salivary gland tumors
#13062
middle Confidence
Subject:
Rapid onsite staining
(Dyeing technology)
→
helps_to_diagnose
→
Object:
rare cases of subcutaneous tumor
(Disease Type)
Original: Rapid onsite staining and cytology#help to diagnose#rare cases of subcutaneous tumor in the absence of primary salivary gland tumors
#13060
middle Confidence
Subject:
Epithelial membrane antigen
(Cell markers)
→
was_positive_in
→
Object:
some large intraepithelial cells
(Cell Type)
Original: Epithelial membrane antigen#was positive in#some large intraepithelial cells
#13056
middle Confidence
Subject:
Fine_needle_aspiration_biopsy
(Medical testing technology)
→
revealed
→
Object:
plump_spindle_cells
(Cell morphology)
Original: Fine needle aspiration biopsy (FNAB)#revealed#plump spindle cells in aggregates
#13040
middle Confidence
Subject:
Spindle-stellate_cells
(Cell Type)
→
are_interspersed_in
→
Object:
myxoid_matrix
(Organizational Structure)
Original: FNAB cytology#revealed#spindle-stellate shaped cells interspersed in a myxoid matrix
#13033
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
shows_no_abnormality_in
→
Object:
CDKN2A
(Gene)
Original: FISH study#revealed#no abnormalities in chromosomes 3/ 7/ 17/ and P16 gene of chromosome 9
#13032
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
shows_no_abnormality_in
→
Object:
chromosome_17
(chromosome)
Original: FISH study#revealed#no abnormalities in chromosomes 3/ 7/ 17/ and P16 gene of chromosome 9
#13031
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
shows_no_abnormality_in
→
Object:
chromosome_7
(chromosome)
Original: FISH study#revealed#no abnormalities in chromosomes 3/ 7/ 17/ and P16 gene of chromosome 9
#13030
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
shows_no_abnormality_in
→
Object:
chromosome_3
(chromosome)
Original: FISH study#revealed#no abnormalities in chromosomes 3/ 7/ 17/ and P16 gene of chromosome 9
#13029
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
exhibits
→
Object:
glomeruloid_architecture
(Organizational Structure)
Original: Tumors#exhibit#tubular/ papillary/ or glomeruloid architectures composed of cells with uniform round nuclei and inconspicuous nucleoli
#13028
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
exhibits
→
Object:
papillary_architecture
(Organizational Structure)
Original: Tumors#exhibit#tubular/ papillary/ or glomeruloid architectures composed of cells with uniform round nuclei and inconspicuous nucleoli
#13027
middle Confidence
Subject:
Metanephric_adenoma
(Tumor type)
→
exhibits
→
Object:
tubular_architecture
(Organizational Structure)
Original: Tumors#exhibit#tubular/ papillary/ or glomeruloid architectures composed of cells with uniform round nuclei and inconspicuous nucleoli
#13026
middle Confidence
Subject:
Specimen
(Clinical specimens)
→
were_stained_for
→
Object:
RCC_marker
(Protein markers)
Original: Specimens#were stained for#WT1/ vimentin/ S-100 protein/ CK7/ P504s/ CD10/ and RCC marker
#13025
middle Confidence
Subject:
Specimen
(Clinical specimens)
→
were_stained_for
→
Object:
CD10
(Protein markers)
Original: Specimens#were stained for#WT1/ vimentin/ S-100 protein/ CK7/ P504s/ CD10/ and RCC marker
#13024
middle Confidence
Subject:
Specimen
(Clinical specimens)
→
were_stained_for
→
Object:
P504s
(Protein markers)
Original: Specimens#were stained for#WT1/ vimentin/ S-100 protein/ CK7/ P504s/ CD10/ and RCC marker
#13023
middle Confidence
Subject:
Specimen
(Clinical specimens)
→
were_stained_for
→
Object:
CK7
(Protein markers)
Original: Specimens#were stained for#WT1/ vimentin/ S-100 protein/ CK7/ P504s/ CD10/ and RCC marker
#13022
middle Confidence
Subject:
Specimen
(Clinical specimens)
→
were_stained_for
→
Object:
S-100_protein
(Protein markers)
Original: Specimens#were stained for#WT1/ vimentin/ S-100 protein/ CK7/ P504s/ CD10/ and RCC marker
#13021
middle Confidence
Subject:
Specimen
(Clinical specimens)
→
were_stained_for
→
Object:
vimentin
(Protein markers)
Original: Specimens#were stained for#WT1/ vimentin/ S-100 protein/ CK7/ P504s/ CD10/ and RCC marker
#13020
middle Confidence
Subject:
Specimen
(Clinical specimens)
→
were_stained_for
→
Object:
WT1
(Protein markers)
Original: Specimens#were stained for#WT1/ vimentin/ S-100 protein/ CK7/ P504s/ CD10/ and RCC marker
#13007
middle Confidence
Subject:
microscopic_appearance
(Histological features)
→
suggests
→
Object:
malignant_neoplasm
(Tumor)
Original: microscopic appearance#suggests#malignant neoplasm due to pseudo-infiltration of fat and atypia of reactive cells
#12994
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD68
(Lysosome-associated proteins)
Original: Neoplastic cells#are positive for#CD68
#12993
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
neuron_specific_enolase
(Enzyme Protein)
Original: Neoplastic cells#are positive for#neuron-specific enolase (NSE)
#12992
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
S100_protein
(Calcium Binding Protein)
Original: Neoplastic cells#are positive for#S100 protein
#12991
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Neoplastic cells#are positive for#vimentin
#12990
middle Confidence
Subject:
Small_cell_component
(Histiocyte subtype)
→
stains_for
→
Object:
Leu_7
(Cell surface molecules)
Original: Small cell component#stains for#Leu-7
#12989
middle Confidence
Subject:
Small_cell_component
(Histiocyte subtype)
→
stains_for
→
Object:
Chromogranin
(Secretory granule protein)
Original: Small cell component#stains for#chromogranin
#12988
middle Confidence
Subject:
Small_cell_component
(Histiocyte subtype)
→
stains_for
→
Object:
neuron_specific_enolase
(Enzyme Protein)
Original: Small cell component#stains for#neuron-specific enolase
#12987
middle Confidence
Subject:
Small_cell_component
(Histiocyte subtype)
→
stains_for
→
Object:
epithelial_membrane_antigen
(Membrane Protein)
Original: Small cell component#stains for#epithelial membrane antigen
#12982
middle Confidence
Subject:
principal_differential_diagnostic_consideration
(Diagnostic considerations)
→
includes
→
Object:
ependymoma
(Tumor type)
Original: principal differential diagnostic considerations#include#gemistocytic astrocytoma/ giant cell glioblastoma/ and ependymoma
#12981
middle Confidence
Subject:
principal_differential_diagnostic_consideration
(Diagnostic considerations)
→
includes
→
Object:
giant_cell_glioblastoma
(Tumor type)
Original: principal differential diagnostic considerations#include#gemistocytic astrocytoma/ giant cell glioblastoma/ and ependymoma
#12980
middle Confidence
Subject:
principal_differential_diagnostic_consideration
(Diagnostic considerations)
→
includes
→
Object:
gemistocytic_astrocytoma
(Tumor type)
Original: principal differential diagnostic considerations#include#gemistocytic astrocytoma/ giant cell glioblastoma/ and ependymoma
#12975
middle Confidence
Subject:
tumor
(Tumor)
→
were_diagnosed_as
→
Object:
carcinoma
(Tumor)
Original: tumors#were diagnosed as#carcinoma with suggested thymus/ lung/ or germ cell origin
#12964
middle Confidence
Subject:
Hepatocellular carcinoma
(Tumor type)
→
can_be_differentiated_from
→
Object:
metastatic_carcinoma
(Tumor type)
Original: Hepatocellular carcinoma#can be differentiated from#metastatic carcinoma by its tendency to recapitulate characteristics of normal hepatocytes
#12938
middle Confidence
Subject:
FNAC
(Diagnostic techniques)
→
revealed
→
Object:
cells_with_distinct_nucleoli
(Cell nucleolus characteristics)
Original: FNAC#revealed#cells with abundant cytoplasm/ small to large nuclei/ and distinct nucleoli
#12937
middle Confidence
Subject:
FNAC
(Diagnostic techniques)
→
revealed
→
Object:
cells_with_small_to_large_nuclei
(Nuclear morphology)
Original: FNAC#revealed#cells with abundant cytoplasm/ small to large nuclei/ and distinct nucleoli
#12936
middle Confidence
Subject:
FNAC
(Diagnostic techniques)
→
revealed
→
Object:
cells_with_abundant_cytoplasm
(Cell morphology)
Original: FNAC#revealed#cells with abundant cytoplasm/ small to large nuclei/ and distinct nucleoli
#12935
middle Confidence
Subject:
A_77-year-old_female
(patient)
→
presented_with
→
Object:
slightly_elevated_nodule_in_skin_on_left_elbow
(Skin nodules)
Original: A 77-year-old female#presented with#a slightly elevated nodule in the skin on her left elbow
#12905
middle Confidence
Subject:
histologic_diagnosis
(Diagnostic Process)
→
includes
→
Object:
lichen_planus_mucosae
(Histological lesions)
Original: histologic diagnoses#include#squamous cell carcinomas/ hyperkeratotic leukoplakias/ and lichen planus mucosae
#12904
middle Confidence
Subject:
histologic_diagnosis
(Diagnostic Process)
→
includes
→
Object:
hyperkeratotic_leukoplakia
(Histological lesions)
Original: histologic diagnoses#include#squamous cell carcinomas/ hyperkeratotic leukoplakias/ and lichen planus mucosae
#12903
middle Confidence
Subject:
histologic_diagnosis
(Diagnostic Process)
→
includes
→
Object:
squamous_cell_carcinoma
(Tumor type)
Original: histologic diagnoses#include#squamous cell carcinomas/ hyperkeratotic leukoplakias/ and lichen planus mucosae
#12902
middle Confidence
Subject:
tumoral_component
(Tumor tissue)
→
shows
→
Object:
lymphocytic_background
(Tissue Microenvironment)
Original: tumoral component#shows#numerous Sternberg-like cells scattered within a lymphocytic background
#12901
middle Confidence
Subject:
tumoral_component
(Tumor tissue)
→
shows
→
Object:
Sternberg-like_cells
(Cell Type)
Original: tumoral component#shows#numerous Sternberg-like cells scattered within a lymphocytic background
#12897
middle Confidence
Subject:
tumor
(Tumor tissue)
→
consists_of
→
Object:
well-circumscribed_dermal-hypodermal_nodules
(Organizational Structure)
Original: tumors#consist of#multiple well-circumscribed dermal-hypodermal nodules
#12896
middle Confidence
Subject:
poorly_differentiated_carcinoma
(Tumor grade)
→
shows
→
Object:
increased_cells_with_large_nuclei
(Nuclear characteristics)
Original: poorly differentiated carcinomas#appear#more pleomorphic due to increased number of cells containing large nuclei
#12895
middle Confidence
Subject:
poorly_differentiated_carcinoma
(Tumor grade)
→
appears
→
Object:
Pleomorphism
(Cellular heterogeneity)
Original: poorly differentiated carcinomas#appear#more pleomorphic due to increased number of cells containing large nuclei
#12894
middle Confidence
Subject:
polygonal_tumour_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD117
(Receptor tyrosine kinases)
Original: Polygonal tumour cells#are positive for#Oct4/ PLAP/ SALL4/ and CD117
#12893
middle Confidence
Subject:
polygonal_tumour_cells
(Tumor cells)
→
are_positive_for
→
Object:
SALL4
(Transcription Factors)
Original: Polygonal tumour cells#are positive for#Oct4/ PLAP/ SALL4/ and CD117
#12892
middle Confidence
Subject:
polygonal_tumour_cells
(Tumor cells)
→
are_positive_for
→
Object:
PLAP
(Enzymes)
Original: Polygonal tumour cells#are positive for#Oct4/ PLAP/ SALL4/ and CD117
#12891
middle Confidence
Subject:
polygonal_tumour_cells
(Tumor cells)
→
are_positive_for
→
Object:
4-Oct
(Transcription Factors)
Original: Polygonal tumour cells#are positive for#Oct4/ PLAP/ SALL4/ and CD117
#12890
middle Confidence
Subject:
tumor
(Tumor tissue)
→
expressed
→
Object:
vascular_markers
(Vascular markers)
Original: tumor#expressed#vascular markers
#12863
middle Confidence
Subject:
adenosquamous_carcinoma
(Tumor diseases)
→
lacks
→
Object:
characteristic_cytology_findings
(Cytological characteristics)
Original: Adenosquamous carcinoma#is proved to have#morphological diversity without characteristic cytology findings
#12862
middle Confidence
Subject:
adenosquamous_carcinoma
(Tumor diseases)
→
is_proved_to_have
→
Object:
morphological_diversity
(Histological diversity)
Original: Adenosquamous carcinoma#is proved to have#morphological diversity without characteristic cytology findings
#12861
middle Confidence
Subject:
cervical_adenocarcinoma_cases
(Tumor diseases)
→
were_classified_by
→
Object:
WHO_classification_based_on_cellular_arrangement
(Clinical classification)
Original: Cervical adenocarcinoma cases#were classified by#WHO classification based on cellular arrangement/ shape/ chromatin pattern/ and nucleolus
#12842
middle Confidence
Subject:
Fibrolamellar_carcinoma
(Tumor type)
→
incorporates
→
Object:
Malaise
(Clinical symptoms)
Original: FLC#frequently incorporates#stomach pain/ weight loss/ and malaise in clinical signs and symptoms
#12841
middle Confidence
Subject:
Fibrolamellar_carcinoma
(Tumor type)
→
incorporates
→
Object:
weight_loss
(Clinical symptoms)
Original: FLC#frequently incorporates#stomach pain/ weight loss/ and malaise in clinical signs and symptoms
#12840
middle Confidence
Subject:
Fibrolamellar_carcinoma
(Tumor type)
→
incorporates
→
Object:
stomach_pain
(Clinical symptoms)
Original: FLC#frequently incorporates#stomach pain/ weight loss/ and malaise in clinical signs and symptoms
#12834
middle Confidence
Subject:
low_grade_transitional_cell_carcinoma
(Tumor type)
→
often_has
→
Object:
difficulty_in_being_separated_from_benign_urothelial_cells
(Difficulties in diagnosis)
Original: Low grade transitional cell carcinomas (TCCs)#often have#great difficulty in being separated from benign urothelial cells
#12809
middle Confidence
Subject:
mucin
(Secretory proteins)
→
distinguishes
→
Object:
squamous_cell_carcinoma_in_situ
(disease)
Original: Protein CEA or mucin#distinguishes#Paget's disease from melanoma or squamous cell carcinoma in-situ
#12808
middle Confidence
Subject:
mucin
(Secretory proteins)
→
distinguishes
→
Object:
melanoma
(disease)
Original: Protein CEA or mucin#distinguishes#Paget's disease from melanoma or squamous cell carcinoma in-situ
#12807
middle Confidence
Subject:
mucin
(Secretory proteins)
→
distinguishes
→
Object:
Paget's_disease
(disease)
Original: Protein CEA or mucin#distinguishes#Paget's disease from melanoma or squamous cell carcinoma in-situ
#12806
middle Confidence
Subject:
CEA
(Secretory proteins)
→
distinguishes
→
Object:
squamous_cell_carcinoma_in_situ
(disease)
Original: Protein CEA or mucin#distinguishes#Paget's disease from melanoma or squamous cell carcinoma in-situ
#12805
middle Confidence
Subject:
CEA
(Secretory proteins)
→
distinguishes
→
Object:
melanoma
(disease)
Original: Protein CEA or mucin#distinguishes#Paget's disease from melanoma or squamous cell carcinoma in-situ
#12804
middle Confidence
Subject:
CEA
(Secretory proteins)
→
distinguishes
→
Object:
Paget's_disease
(disease)
Original: Protein CEA or mucin#distinguishes#Paget's disease from melanoma or squamous cell carcinoma in-situ
#12803
middle Confidence
Subject:
nipple_scrape_cytology
(Cytological methods)
→
diagnoses
→
Object:
mammary_Paget's_disease
(disease)
Original: Nipple scrape cytology#diagnoses#mammary Paget's disease
#12802
middle Confidence
Subject:
scrape_smears
(Cytological methods)
→
diagnoses
→
Object:
Paget's_disease
(disease)
Original: Cytological diagnosis of Paget's disease#was performed by#scrape smears
#12788
middle Confidence
Subject:
abundant_inflammatory_cells
(Immune cells)
→
could_obscure
→
Object:
neoplastic_histiocytes
(Tumor cells)
Original: abundant inflammatory cells#could obscure#neoplastic histiocytes in distinguishing inflammatory conditions
#12785
middle Confidence
Subject:
cytopathological_features_of_CLCC_of_the_lung
(Cytopathological characteristics)
→
are_emphasized_in
→
Object:
differential_diagnostic_considerations
(Diagnostic Process)
Original: cytopathological features of CLCC of the lung#are emphasized in#differential diagnostic considerations
#12782
middle Confidence
Subject:
nucleoli
(Nuclear structure)
→
increases
→
Object:
diagnostic_probability_of_endometrial_hyperplasia
(Clinical diagnosis probability)
Original: presence of nucleoli#increases#diagnostic probability of endometrial hyperplasias
#12725
middle Confidence
Subject:
AgNOR_counts
(Nucleolus-associated organic silver stain count)
→
were_higher_in
→
Object:
ameloblastoma
(Disease phenotype)
Original: AgNOR counts#were higher in#KCOT and ameloblastoma than dentigerous cyst
#12724
middle Confidence
Subject:
AgNOR_counts
(Nucleolus-associated organic silver stain count)
→
were_higher_in
→
Object:
KCOT
(Disease phenotype)
Original: AgNOR counts#were higher in#KCOT and ameloblastoma than dentigerous cyst
#12723
middle Confidence
Subject:
AgNOR
(Nucleolus-associated organic silver staining structures)
→
are_used_to_study
→
Object:
cell_proliferation
(Cellular Processes)
Original: AgNOR#are used to study#cell proliferation in tumors
#12550
middle Confidence
Subject:
ORF2
(Transposon protein)
→
is_expressed_early_in
→
Object:
pre-neoplastic_lesions
(Precancerous lesions)
Original: RT-encoding ORF2#is expressed early in#pre-neoplastic lesions
#12549
middle Confidence
Subject:
CCND1
(Protein coding genes)
→
facilitates
→
Object:
accurate_diagnosis_of_CCND1_abnormality
(Diagnostic Process)
Original: Cytogenetic studies#facilitate#accurate diagnosis of BCL-1/cyclin D1 abnormalities
#12548
middle Confidence
Subject:
BCL1
(Protein coding genes)
→
facilitates
→
Object:
accurate_diagnosis_of_BCL1_abnormality
(Diagnostic Process)
Original: Cytogenetic studies#facilitate#accurate diagnosis of BCL-1/cyclin D1 abnormalities
#12546
middle Confidence
Subject:
BCL1_gene_rearrangement
(Gene rearrangement)
→
is_identified_by
→
Object:
PCR_or_Southern_blot
(Molecular diagnostic technology)
Original: BCL-1 gene rearrangements#were identified by#PCR or Southern blot analysis in two cases
#12545
middle Confidence
Subject:
t(11;14)(q13;q32)_karyotype
(Chromosomal translocation)
→
is_documented_in
→
Object:
tumor
(Tumor cells)
Original: Karyotypic t(11;14)(q13;q32)#was documented in#one tumor
#12541
middle Confidence
Subject:
Hodgkinoid_histiocytosis
(Disease phenotype)
→
mimics
→
Object:
classic_Hodgkin_lymphoma
(Disease phenotype)
Original: Hodgkinoid histiocytosis#mimics#morphologically classic Hodgkin lymphoma
#12530
middle Confidence
Subject:
CD30
(Membrane Protein)
→
is_expressed_in
→
Object:
T-cell_lineage
(Immune cell types)
Original: All cases#showed evidence of#T-cell lineage with CD30+ expression
#12523
middle Confidence
Subject:
AgNOR
(Nucleolar Organizing Region-associated Protein)
→
correlates_with
→
Object:
intestinal_metaplasia
(Disease phenotype)
Original: Results of PCNA and AgNOR#significantly correlated with#intestinal metaplasia group
#12522
middle Confidence
Subject:
PCNA
(Cell cycle proteins)
→
correlates_with
→
Object:
intestinal_metaplasia
(Disease phenotype)
Original: Results of PCNA and AgNOR#significantly correlated with#intestinal metaplasia group
#12309
middle Confidence
Subject:
lymphoid_hemopathies
(Disease phenotype)
→
are_characterized_by
→
Object:
lymphoid_cells_with_irregular_nucleus
(Abnormal cell morphology)
Original: Lymphoid hemopathies#are characterized by#lymphoid cells with irregular nucleus and prominent nucleolus
#12082
middle Confidence
Subject:
Anaplastic_large_cell_lymphoma
(Tumor diseases)
→
accompanied_by
→
Object:
B_symptoms
(Clinical symptoms)
Original: ALCL#presents in#advanced clinical stages with B symptoms
#12052
middle Confidence
Subject:
prostatic_stem_cells
(Stem Cells)
→
requires
→
Object:
characterization_techniques
(Technical methods)
Original: Identification of prostatic stem cells#requires#techniques for characterization of stem cells for patient treatment
#12047
middle Confidence
Subject:
Electron_microscopical_morphometry
(Imaging technology)
→
analyzes
→
Object:
ACTH_secreting_adenomas
(Adenoma)
Original: Electron microscopical morphometry#analyzes#ACTH-secreting adenomas in Cushing's disease and Nelson's syndrome
#12046
middle Confidence
Subject:
Raman_spectra
(Molecular spectroscopy)
→
discriminates
→
Object:
Cytoplasm
(Cytoplasm)
Original: Raman spectra#discriminates#nucleoli/ nuclei/ and cytoplasm in oral epithelial cancer and dysplastic cell lines
#12045
middle Confidence
Subject:
Raman_spectra
(Molecular spectroscopy)
→
discriminates
→
Object:
nuclei
(Nucleus)
Original: Raman spectra#discriminates#nucleoli/ nuclei/ and cytoplasm in oral epithelial cancer and dysplastic cell lines
#12044
middle Confidence
Subject:
Raman_spectra
(Molecular spectroscopy)
→
discriminates
→
Object:
nucleoli
(Nucleolus)
Original: Raman spectra#discriminates#nucleoli/ nuclei/ and cytoplasm in oral epithelial cancer and dysplastic cell lines
#12043
middle Confidence
Subject:
Precursor_rRNA_assay
(Molecular detection technology)
→
detects
→
Object:
increased_rRNA_production
(Molecular products)
Original: Precursor rRNA assay#detects#increased rRNA production in various tumor types
#12041
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
showed
→
Object:
division_of_nuclei
(Nuclear division)
Original: Tumor cells#showed#irregular shape/ chromatin clumps/ and division of nuclei
#12040
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
showed
→
Object:
chromatin_clumps
(Chromatin condensation)
Original: Tumor cells#showed#irregular shape/ chromatin clumps/ and division of nuclei
#12039
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
showed
→
Object:
irregular_shape
(Abnormal cell morphology)
Original: Tumor cells#showed#irregular shape/ chromatin clumps/ and division of nuclei
#11958
middle Confidence
Subject:
normal_colonic_mucosa
(Normal colon mucosa)
→
were_assessed_with
→
Object:
AgNOR_technique
(Silver staining technique)
Original: colonic adenocarcinomas and normal colonic mucosae#were assessed with#AgNOR technique
#11957
middle Confidence
Subject:
colonic_adenocarcinoma
(Adenocarcinoma tissue)
→
were_assessed_with
→
Object:
AgNOR_technique
(Silver staining technique)
Original: colonic adenocarcinomas and normal colonic mucosae#were assessed with#AgNOR technique
#11956
middle Confidence
Subject:
AgNOR_precipitates
(Silver-stained nucleolar-associated granules)
→
were_studied_in
→
Object:
colonscopic_biopsy_specimens_of_UC
(Colonoscopic biopsy specimen)
Original: specific intranuclear AgNOR silver precipitates (AgNORs)#were studied in#colonscopic biopsy specimens of ulcerative colitis (UC)
#11949
middle Confidence
Subject:
nuclear_p16
(Nuclear protein)
→
produces
→
Object:
positive_result_in_melanocyte_hyperplasia
(Histopathological results)
Original: nuclear p16#produced#positive results in melanocytosis and melanocyte hyperplasia components
#11948
middle Confidence
Subject:
nuclear_p16
(Nuclear protein)
→
produces
→
Object:
positive_result_in_melanocytosis
(Histopathological results)
Original: nuclear p16#produced#positive results in melanocytosis and melanocyte hyperplasia components
#11932
middle Confidence
Subject:
proliferating_tubules
(Tissue morphology)
→
negative_for
→
Object:
prostate_acid_phosphatase
(Enzymes)
Original: Proliferating tubules#reacted with#keratin 903 and were negative for prostate-specific antigen and prostate acid phosphatase
#11931
middle Confidence
Subject:
proliferating_tubules
(Tissue morphology)
→
negative_for
→
Object:
prostate_specific_antigen
(protein)
Original: Proliferating tubules#reacted with#keratin 903 and were negative for prostate-specific antigen and prostate acid phosphatase
#11930
middle Confidence
Subject:
proliferating_tubules
(Tissue morphology)
→
reacted_with
→
Object:
keratin_903
(protein)
Original: Proliferating tubules#reacted with#keratin 903 and were negative for prostate-specific antigen and prostate acid phosphatase
#11925
middle Confidence
Subject:
histological_features
(Histological characteristics)
→
leads_to
→
Object:
understanding_of_malignant_transformation_factors
(Mechanisms of tumor transformation)
Original: p80/ALK overexpression#is associated with#a good prognosis in t(2:5)-positive tumors
#11924
middle Confidence
Subject:
clinical_features
(Clinical characteristics)
→
leads_to
→
Object:
understanding_of_malignant_transformation_factors
(Mechanisms of tumor transformation)
Original: Lymphoid cells#infiltrate#multiple lymph nodes/ liver/ lung/ and spleen
#11915
middle Confidence
Subject:
basement_membrane
(Organizational Structure)
→
is_disrupted_in
→
Object:
carcinoma
(Tumor tissue)
Original: intact basement membrane#is present in#AAH compared to carcinoma
#11914
middle Confidence
Subject:
basement_membrane
(Organizational Structure)
→
is_intact_in
→
Object:
AAH
(Benign tissue)
Original: intact basement membrane#is present in#AAH compared to carcinoma
#11913
middle Confidence
Subject:
mean_nucleolar_diameter
(Cell morphological characteristics)
→
is_smaller_in
→
Object:
AAH
(Benign tissue)
Original: mean nucleolar diameter#is larger in#carcinoma compared to AAH
#11912
middle Confidence
Subject:
mean_nucleolar_diameter
(Cell morphological characteristics)
→
is_larger_in
→
Object:
carcinoma
(Tumor tissue)
Original: mean nucleolar diameter#is larger in#carcinoma compared to AAH
#11880
middle Confidence
Subject:
AgNOR
(Nucleolar organizing region)
→
is_useful_for
→
Object:
proliferative_activity_estimation
(Cellular Processes)
Original: AgNOR#is useful for#estimation of proliferative activity in soft tissue sarcoma
#11874
middle Confidence
Subject:
Histological_markers
(Histological markers)
→
are_used_to
→
Object:
distinguish_malignant_parathyroid_tumors
(Differentiation of malignant parathyroid tumors)
Original: Histological markers#are used to#distinguish benign and malignant parathyroid tumors
#11873
middle Confidence
Subject:
Histological_markers
(Histological markers)
→
are_used_to
→
Object:
distinguish_benign_parathyroid_tumors
(Differentiation of benign parathyroid tumors)
Original: Histological markers#are used to#distinguish benign and malignant parathyroid tumors
#11871
middle Confidence
Subject:
AgNOR_technique
(Molecular detection technology)
→
detects
→
Object:
argyrophilic_proteins_in_NOR
(Silver affinity protein)
Original: AgNOR technique#detects#argyrophilic proteins in nucleolar organizer region
#11854
middle Confidence
Subject:
BCL2
(Apoptosis regulatory proteins)
→
is_upregulated_in
→
Object:
basal_cell_proliferative_lesions
(Histological phenotype)
Original: Elevated expression of bcl-2 and higher Ki-67 index#may aid in#diagnosis of basal cell proliferative lesions
#11850
middle Confidence
Subject:
Argyrophilic_Nucleolar_Organizer_Region
(Nucleolar organizer region)
→
was_studied_in
→
Object:
metastatic_lymph_nodes
(Metastatic lymph nodes)
Original: Argyrophilic Nucleolar Organizer Region (AgNOR)#was studied in#laryngeal cancer and metastatic lymph nodes
#11849
middle Confidence
Subject:
Argyrophilic_Nucleolar_Organizer_Region
(Nucleolar organizer region)
→
was_studied_in
→
Object:
laryngeal_cancer
(Laryngeal cancer)
Original: Argyrophilic Nucleolar Organizer Region (AgNOR)#was studied in#laryngeal cancer and metastatic lymph nodes
#11845
middle Confidence
Subject:
Alpha-SMA_expression
(Smooth muscle actin expression)
→
is_found_only_in
→
Object:
stromal_part_of_ameloblastoma
(Tumor stroma)
Original: Alpha-SMA expression#is found only in#stromal part of ameloblastoma
#11844
middle Confidence
Subject:
AgNOR_counts
(Nucleolar organizer region count)
→
may_be_useful_for
→
Object:
diagnosis_of_cellular_activity
(Cell viability diagnosis)
Original: AgNOR counts#may be useful for#diagnosis of cellular activity in uterine myomatous tumors
#11843
middle Confidence
Subject:
p53_staining
(Protein expression status)
→
is_absent_in
→
Object:
study_cases
(Study Sample)
Original: p53 staining#is absent in#14 of 15 study cases
#11842
middle Confidence
Subject:
gastric_dysplasia-like_epithelial_atypia
(Abnormal epithelial morphology)
→
is_associated_with
→
Object:
gland_involvement
(Involvement of glandular structures)
Original: gastric dysplasia-like epithelial atypia#is associated with#a flat gross appearance/ patchy distribution/ foveolar and gland involvement
#11841
middle Confidence
Subject:
gastric_dysplasia-like_epithelial_atypia
(Abnormal epithelial morphology)
→
is_associated_with
→
Object:
foveolar_involvement
(Involvement of crypt structures)
Original: gastric dysplasia-like epithelial atypia#is associated with#a flat gross appearance/ patchy distribution/ foveolar and gland involvement
#11840
middle Confidence
Subject:
gastric_dysplasia-like_epithelial_atypia
(Abnormal epithelial morphology)
→
is_associated_with
→
Object:
patchy_distribution
(Tissue distribution characteristics)
Original: gastric dysplasia-like epithelial atypia#is associated with#a flat gross appearance/ patchy distribution/ foveolar and gland involvement
#11839
middle Confidence
Subject:
gastric_dysplasia-like_epithelial_atypia
(Abnormal epithelial morphology)
→
is_associated_with
→
Object:
flat_gross_appearance
(Macroscopic morphological characteristics)
Original: gastric dysplasia-like epithelial atypia#is associated with#a flat gross appearance/ patchy distribution/ foveolar and gland involvement
#11823
middle Confidence
Subject:
histopathology
(Histopathology)
→
correlates_with
→
Object:
tumor_ploidy
(Tumor ploidy)
Original: Histopathology of 66 cases#correlates with#tumor ploidy
#11821
middle Confidence
Subject:
NSE
(Neuron-specific enolase)
→
shows_positive_reactivity_in
→
Object:
tumors
(Tumor)
Original: Immunostaining#reveals#positive NSE reactivity in 10/10 tumors and weak CgA staining in 4/10 tumors
#11817
middle Confidence
Subject:
mean_number_of_nucleolar_organizer_regions
(Molecular markers)
→
assists_in
→
Object:
distinguishing_malignant_transitional_tumors_of_the_nose
(Disease phenotype)
Original: Mean numbers of nucleolar organizer regions#assist in#distinguishing benign and malignant transitional tumors of the nose
#11816
middle Confidence
Subject:
mean_number_of_nucleolar_organizer_regions
(Molecular markers)
→
assists_in
→
Object:
distinguishing_benign_transitional_tumors
(Disease phenotype)
Original: Mean numbers of nucleolar organizer regions#assist in#distinguishing benign and malignant transitional tumors of the nose
#11797
middle Confidence
Subject:
Immunohistochemical_study
(Detection Methods)
→
showed_positive_staining_for
→
Object:
CD68
(protein)
Original: Immunohistochemical study#showed positive staining for#CD68
#11796
middle Confidence
Subject:
Immunohistochemical_study
(Detection Methods)
→
showed_positive_staining_for
→
Object:
neuron-specific_enolase
(protein)
Original: Immunohistochemical study#showed positive staining for#neuron-specific enolase
#11795
middle Confidence
Subject:
Immunohistochemical_study
(Detection Methods)
→
showed_positive_staining_for
→
Object:
S-100_protein
(protein)
Original: Immunohistochemical study#showed positive staining for#S-100 protein
#11784
middle Confidence
Subject:
NORs
(Nucleolar organizing region)
→
was_examined_in
→
Object:
smooth_muscle_tumors
(disease)
Original: Smooth muscle tumors#were examined for#vimentin/ desmin/ S100/ fibronectin/ cytokeratin/ and NORs
#11783
middle Confidence
Subject:
cytokeratin
(Cytokeratin)
→
was_examined_in
→
Object:
smooth_muscle_tumors
(disease)
Original: Smooth muscle tumors#were examined for#vimentin/ desmin/ S100/ fibronectin/ cytokeratin/ and NORs
#11782
middle Confidence
Subject:
fibronectin
(Extracellular matrix proteins)
→
was_examined_in
→
Object:
smooth_muscle_tumors
(disease)
Original: Smooth muscle tumors#were examined for#vimentin/ desmin/ S100/ fibronectin/ cytokeratin/ and NORs
#11781
middle Confidence
Subject:
S100
(Calcium Binding Protein)
→
was_examined_in
→
Object:
smooth_muscle_tumors
(disease)
Original: Smooth muscle tumors#were examined for#vimentin/ desmin/ S100/ fibronectin/ cytokeratin/ and NORs
#11780
middle Confidence
Subject:
desmin
(Intermediate filament protein)
→
was_examined_in
→
Object:
smooth_muscle_tumors
(disease)
Original: Smooth muscle tumors#were examined for#vimentin/ desmin/ S100/ fibronectin/ cytokeratin/ and NORs
#11779
middle Confidence
Subject:
vimentin
(Intermediate filament protein)
→
was_examined_in
→
Object:
smooth_muscle_tumors
(disease)
Original: Smooth muscle tumors#were examined for#vimentin/ desmin/ S100/ fibronectin/ cytokeratin/ and NORs
#11778
middle Confidence
Subject:
AgNORs
(Nucleolar organizing region)
→
are_implicated_in
→
Object:
malignant_lesions_of_oropharynx
(Malignant lesions)
Original: AgNORs#are implicated in#benign and malignant lesions of oral cavity and oropharynx
#11777
middle Confidence
Subject:
AgNORs
(Nucleolar organizing region)
→
are_implicated_in
→
Object:
benign_lesions_of_oropharynx
(Benign lesions)
Original: AgNORs#are implicated in#benign and malignant lesions of oral cavity and oropharynx
#11776
middle Confidence
Subject:
AgNORs
(Nucleolar organizing region)
→
are_implicated_in
→
Object:
malignant_lesions_of_oral_cavity
(Malignant lesions)
Original: AgNORs#are implicated in#benign and malignant lesions of oral cavity and oropharynx
#11775
middle Confidence
Subject:
AgNORs
(Nucleolar organizing region)
→
are_implicated_in
→
Object:
benign_lesions_of_oral_cavity
(Benign lesions)
Original: AgNORs#are implicated in#benign and malignant lesions of oral cavity and oropharynx
#11750
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
serve_as
→
Object:
diagnostic_clues
(Diagnostic Tips)
Original: AgNORs#serve as#diagnostic and prognostic clues in tumors
#11749
middle Confidence
Subject:
morphometric_evaluation_of_AgNOR
(Morphometric analysis)
→
detects
→
Object:
epithelial_foci_in_malignant_transformation
(Malignant transformation)
Original: Morphometric evaluation of AgNOR#detects#epithelial foci in malignant transformation
#11748
middle Confidence
Subject:
CD34
(Receptor protein)
→
is_demonstrated_in
→
Object:
histologic_samples
(Histological samples)
Original: CD34 staining pattern#is demonstrated in#histologic samples
#11747
middle Confidence
Subject:
Silver_staining
(Dyeing technology)
→
is_used_for
→
Object:
cell_proliferation_measurement
(Cellular Processes)
Original: Silver staining#is used for#measuring cell proliferation in tissue specimens
#11739
middle Confidence
Subject:
PCNA
(Proliferating cell nuclear antigen)
→
immunoreactivity_was_determined_in
→
Object:
breast_samples
(Breast samples)
Original: interphasic NOR modifications and PCNA immunoreactivity#were determined in#breast samples
#11738
middle Confidence
Subject:
interphasic_NOR_modifications
(Nucleolar organizer compartment modification)
→
were_determined_in
→
Object:
breast_samples
(Breast samples)
Original: interphasic NOR modifications and PCNA immunoreactivity#were determined in#breast samples
#11737
middle Confidence
Subject:
AgNOR
(Nucleolar organizer region-associated silver stain)
→
was_evaluated_in
→
Object:
uveal_malignant_melanomas
(Uveal melanoma)
Original: AgNOR#was evaluated in#uveal malignant melanomas
#11735
middle Confidence
Subject:
Ki-67
(Cell proliferation-related proteins)
→
was_studied_in
→
Object:
cutaneous_melanocytic_lesions
(Melanocytic skin lesions)
Original: AgNOR and Ki-67 immunoreactivity#were studied in#cutaneous melanocytic lesions
#11704
middle Confidence
Subject:
SNORA68
(Small nuclear RNA)
→
expression_was_evaluated_in
→
Object:
breast_cancer_tissues
(Tumor tissue)
Original: SNORA68 expression#was evaluated in#breast cancer tissues by in situ hybridization and qRT-PCR
#11700
middle Confidence
Subject:
AgNOR
(Nucleolar Organizing Region-associated Protein)
→
is_important_for
→
Object:
diagnostic_purposes
(Diagnostic effect)
Original: Distribution of AgNORs#is important for#diagnostic and prognostic purposes in tumor pathology
#11699
middle Confidence
Subject:
AgNOR
(Nucleolar Organizing Region-associated Protein)
→
is_counted_in
→
Object:
malignant_tumors_of_minor_salivary_glands
(Malignant tumors)
Original: AgNORs#were counted in#benign and malignant tumors of minor salivary glands
#11698
middle Confidence
Subject:
AgNOR
(Nucleolar Organizing Region-associated Protein)
→
is_counted_in
→
Object:
benign_tumors_of_minor_salivary_glands
(Benign tumors)
Original: AgNORs#were counted in#benign and malignant tumors of minor salivary glands
#11686
middle Confidence
Subject:
AgNOR_staining
(Staining method)
→
is_tested_for
→
Object:
well_differentiated_carcinomas
(Tumor)
Original: AgNOR staining#is tested for#diagnosing borderline tumors and well-differentiated carcinomas
#11685
middle Confidence
Subject:
AgNOR_staining
(Staining method)
→
is_tested_for
→
Object:
borderline_tumors
(Tumor)
Original: AgNOR staining#is tested for#diagnosing borderline tumors and well-differentiated carcinomas
#11672
middle Confidence
Subject:
AgNOR_counts_in_OSCC
(AgNOR Count)
→
are_higher_than
→
Object:
AgNOR_counts_in_other_lesions
(AgNOR Count)
Original: Control oral squamous cell carcinoma tissues#had#significantly higher AgNOR counts than other lesions tested
#11654
middle Confidence
Subject:
grade_III_ductal_breast_carcinoma
(Tumor grade)
→
were_distinguished_from
→
Object:
grade_I_ductal_breast_carcinoma
(Tumor grade)
Original: grades II and III ductal breast carcinoma#were distinguished from#grade I tumors
#11653
middle Confidence
Subject:
grade_II_ductal_breast_carcinoma
(Tumor grade)
→
were_distinguished_from
→
Object:
grade_I_ductal_breast_carcinoma
(Tumor grade)
Original: grades II and III ductal breast carcinoma#were distinguished from#grade I tumors
#11652
middle Confidence
Subject:
antigen_retrieval_methods
(Antigen retrieval technology)
→
produced
→
Object:
cytoplasmic_and_nuclear_staining_of_tumor_cells
(Histological staining)
Original: antigen retrieval methods#produced#tumor cell cytoplasmic and nuclear staining
#11651
middle Confidence
Subject:
carcinomas_with_high_mitoses_large_nuclei_increased_NC_ratio_large_nucleoli
(Tumors with specific pathological phenotypes)
→
exhibit
→
Object:
thermographically_suspect_pictures
(Suspicious thermal imaging performance)
Original: Carcinomas with numerous mitoses/ large cell nuclei/ increased N/C ratio/ and large nucleoli#exhibit#thermographically suspect pictures
#11614
middle Confidence
Subject:
PEComa
(Tumor type)
→
can_arise_in
→
Object:
kidney
(organ)
Original: Pathologists#should recognize#PEComa with TFE3 gene fusion can arise in the kidney
#11610
middle Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
co-expresses
→
Object:
vimentin
(Intermediate filament protein)
Original: Neoplastic cells#co-express#CK and vimentin
#11609
middle Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
co-expresses
→
Object:
CK
(Cytoskeletal proteins)
Original: Neoplastic cells#co-express#CK and vimentin
#11605
middle Confidence
Subject:
FNA_smear
(Diagnostic techniques)
→
showed
→
Object:
plasmacytoid_cell
(Cell Type)
Original: FNA smears#showed#large plasmacytoid cells with eccentrically placed nuclei/ prominent nucleoli/ and moderate amounts of basophilic cytoplasm
#11600
middle Confidence
Subject:
neurofilament
(Cytoskeletal proteins)
→
is_downregulated_in
→
Object:
virus-negative_cases
(Disease classification)
Original: neurofilament#exhibits#frequent lack of expression in virus-negative cases
#11582
middle Confidence
Subject:
psammomatous_calcifications
(Calcification deposits)
→
identified_in
→
Object:
peritoneal_washings
(Peritoneal lavage fluid)
Original: search#identified#37 cases of peritoneal washings with psammomatous calcifications
#11581
middle Confidence
Subject:
FDCT
(Disease name)
→
is_characterized_by
→
Object:
spindle_to_ovoid_cells_with_distinct_nucleoli
(Cell morphology)
Original: FDCT#is characterized by#spindle to ovoid cells with distinct nucleoli
#11578
middle Confidence
Subject:
epithelioid_angiosarcoma
(Tumor tissue)
→
shows
→
Object:
mitotic_activity
(Cell division)
Original: epithelioid angiosarcomas#show#marked cytologic atypia and mitotic activity
#11577
middle Confidence
Subject:
epithelioid_angiosarcoma
(Tumor tissue)
→
shows
→
Object:
marked_cytologic_atypia
(Abnormal cell morphology)
Original: epithelioid angiosarcomas#show#marked cytologic atypia and mitotic activity
#11576
middle Confidence
Subject:
epithelioid_angiosarcoma
(Tumor tissue)
→
is_characterized_by
→
Object:
neoplastic_cellular_proliferation
(Cellular Processes)
Original: epithelioid angiosarcomas#are characterized by#neoplastic cellular proliferation with round to oval nuclei and prominent nucleoli
#11575
middle Confidence
Subject:
bone_marrow_biopsy
(Histological examination)
→
showed
→
Object:
typical_features_of_T-LBL
(Disease phenotype)
Original: bone marrow biopsy#showed#typical features of T-LBL
#11571
middle Confidence
Subject:
imprint_cytology
(Impression cytology)
→
revealed
→
Object:
round_to_ovoid_tumor_cells_with_mild_pleomorphism
(Tumor cell morphology)
Original: Imprint cytology#revealed#round-to-ovoid tumor cells with mild pleomorphism
#11519
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
display
→
Object:
rounded_astrocytic_giant_cells_with_prominent_nucleoli
(Cell morphology)
Original: Tumor cells#displayed#a population of rounded astrocytic giant cells with prominent nucleoli
#11507
middle Confidence
Subject:
haematoxylin_and_eosin_stained_slides
(Pathological sections)
→
are_from
→
Object:
cancer_patients
(patient)
Original: Digital cell image analysis#is carried out on#haematoxylin and eosin-stained slides of cancer patients
#11497
middle Confidence
Subject:
AgNOR_protein_quantity
(Protein expression)
→
aids
→
Object:
cytological_diagnosis
(Diagnostic Process)
Original: AgNOR protein quantity#reflects#cervical epithelium in situ and aids cytological diagnosis
#11496
middle Confidence
Subject:
AgNOR_protein_quantity
(Protein expression)
→
reflects
→
Object:
cervical_epithelium_in_situ
(Tissue phenotype)
Original: AgNOR protein quantity#reflects#cervical epithelium in situ and aids cytological diagnosis
#11495
middle Confidence
Subject:
AgNOR_PI
(Nuclear Organism Markers)
→
is_significantly_higher_in
→
Object:
patients_with_HBsAg_positivity
(Patients with HBsAg positive)
Original: AgNOR-PI#is significantly higher in#patients with liver cell dysplasia and HBsAg positivity
#11494
middle Confidence
Subject:
AgNOR_PI
(Nuclear Organism Markers)
→
is_significantly_higher_in
→
Object:
patients_with_liver_cell_dysplasia
(Patients with hepatocellular abnormalities)
Original: AgNOR-PI#is significantly higher in#patients with liver cell dysplasia and HBsAg positivity
#11490
middle Confidence
Subject:
vesicular_granular_adipophilin_positivity
(Lipoprotein positive)
→
supplements
→
Object:
diagnosis_of_infiltrative_tumors
(Disease diagnosis)
Original: p53 and vesicular granular adipophilin positivity#supplement#diagnosis of infiltrative tumors
#11489
middle Confidence
Subject:
adipophilin_positivity
(Lipoprotein positive)
→
is_detected_in
→
Object:
paraffin_sections_in_invasive_tumors
(Tissue specimens)
Original: Adipophilin positivity#is detected in#paraffin sections in invasive tumors
#11479
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region-associated molecule)
→
correlates_with
→
Object:
ESR1
(Nuclear receptor proteins)
Original: estrogen receptors (ER)#correlate with#argyrophilic nucleolar organizer regions (AgNORs) in breast cancer cells
#11478
middle Confidence
Subject:
ESR1
(Nuclear receptor proteins)
→
correlates_with
→
Object:
AgNORs
(Nucleolar organizer region-associated molecule)
Original: estrogen receptors (ER)#correlate with#argyrophilic nucleolar organizer regions (AgNORs) in breast cancer cells
#11466
middle Confidence
Subject:
Pancreatic_lesions_in_children
(Disease phenotype)
→
have
→
Object:
wide_range_of_histopathological_types
(Histological type)
Original: Pancreatic lesions in children#have#a wide range of histopathological types
#11456
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
was_discussed_with
→
Object:
other_metastatic_small_cell_tumors
(Tumor subtype)
Original: The differential diagnosis#was discussed#with other metastatic small cell tumors
#11446
middle Confidence
Subject:
histology
(Pathological characteristics)
→
suggested
→
Object:
high-grade_lymphoma
(Tumor diseases)
Original: The histology#suggested#a high-grade lymphoma despite indolent clinical evolution
#11443
middle Confidence
Subject:
PLCG2
(Protein coding genes)
→
may_be_exploited_as
→
Object:
potential_diagnostic_target
(Potential diagnostic targets)
Original: Metabolic pathway-related genes#may be exploited as#potential targets for diagnosis and treatment
#11441
middle Confidence
Subject:
PLCB4
(Protein coding genes)
→
may_be_exploited_as
→
Object:
potential_diagnostic_target
(Potential diagnostic targets)
Original: Metabolic pathway-related genes#may be exploited as#potential targets for diagnosis and treatment
#11439
middle Confidence
Subject:
PLA2G6
(Protein coding genes)
→
may_be_exploited_as
→
Object:
potential_diagnostic_target
(Potential diagnostic targets)
Original: Metabolic pathway-related genes#may be exploited as#potential targets for diagnosis and treatment
#11437
middle Confidence
Subject:
PLA2G2A
(Protein coding genes)
→
may_be_exploited_as
→
Object:
potential_diagnostic_target
(Potential diagnostic targets)
Original: Metabolic pathway-related genes#may be exploited as#potential targets for diagnosis and treatment
#11435
middle Confidence
Subject:
PLA2G4E
(Protein coding genes)
→
may_be_exploited_as
→
Object:
potential_diagnostic_target
(Potential diagnostic targets)
Original: Metabolic pathway-related genes#may be exploited as#potential targets for diagnosis and treatment
#11432
middle Confidence
Subject:
histological_examination
(Pathological examination method)
→
shows
→
Object:
tumor_with_large_or_pleomorphic_epithelioid_cells
(Tumor cells)
Original: Histological examination#showed#tumor with numerous large or pleomorphic epithelioid cells with large vesicular nuclei and prominent nucleoli
#11431
middle Confidence
Subject:
histopathological_examination
(Pathological examination method)
→
shows
→
Object:
tumor_nests
(Tumor tissue structure)
Original: Histopathological examination#showed#tumor nests near the necrotic foci arranged as angulated tubules/ tubulopapillary/ and glandular structures
#11404
middle Confidence
Subject:
mammary_analog_secretory_carcinoma
(Tumor type)
→
arises_in
→
Object:
thyroid
(organ)
Original: mammary analog secretory carcinoma (MASC)#arises in#thyroid
#11398
middle Confidence
Subject:
Cytoplasm
(Cytoplasm)
→
shows
→
Object:
Fine_to_coarse_granularity
(Cell morphology)
Original: Cytoplasm#is#eosinophilic with fine to coarse granularity
#11397
middle Confidence
Subject:
Cytoplasm
(Cytoplasm)
→
is
→
Object:
Eosinophilic
(Cell morphology)
Original: Cytoplasm#is#eosinophilic with fine to coarse granularity
#11396
middle Confidence
Subject:
Nuclei
(Nucleus)
→
have
→
Object:
Prominent_centrally_located_nucleoli
(Cell morphology)
Original: Nuclei#are#large and vesicular with prominent centrally located nucleoli
#11395
middle Confidence
Subject:
Nuclei
(Nucleus)
→
are
→
Object:
Large_and_vesicular
(Cell morphology)
Original: Nuclei#are#large and vesicular with prominent centrally located nucleoli
#11376
middle Confidence
Subject:
ERRT
(Tumor type)
→
was_diagnosed_by
→
Object:
Immunohistochemistry
(Diagnostic techniques)
Original: A case of ERRT with intraspinal extension#was diagnosed by#fine needle aspiration cytology (FNAC) and immunohistochemistry
#11375
middle Confidence
Subject:
ERRT
(Tumor type)
→
was_diagnosed_by
→
Object:
fine needle aspiration cytology
(Diagnostic techniques)
Original: A case of ERRT with intraspinal extension#was diagnosed by#fine needle aspiration cytology (FNAC) and immunohistochemistry
#11374
middle Confidence
Subject:
histopathology
(Histological detection technology)
→
was_compatible_with
→
Object:
LCLC
(Tumor type)
Original: Tru-cut biopsy from the lung lesion#was performed#and histopathology was compatible with LCLC
#11362
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contained
→
Object:
alpha_1_antitrypsin
(Protease inhibitors)
Original: Some tumor cells#contained#cytokeratin CAM5.2/ vimentin/ neurofilament/ neuron-specific enolase/ alpha-1 antitrypsin
#11361
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contained
→
Object:
neuron_specific_enolase
(Glycolytic enzymes)
Original: Some tumor cells#contained#cytokeratin CAM5.2/ vimentin/ neurofilament/ neuron-specific enolase/ alpha-1 antitrypsin
#11360
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contained
→
Object:
neurofilament
(Neural cytoskeleton proteins)
Original: Some tumor cells#contained#cytokeratin CAM5.2/ vimentin/ neurofilament/ neuron-specific enolase/ alpha-1 antitrypsin
#11359
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contained
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Some tumor cells#contained#cytokeratin CAM5.2/ vimentin/ neurofilament/ neuron-specific enolase/ alpha-1 antitrypsin
#11358
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contained
→
Object:
cytokeratin_CAM5.2
(Cytoskeletal proteins)
Original: Some tumor cells#contained#cytokeratin CAM5.2/ vimentin/ neurofilament/ neuron-specific enolase/ alpha-1 antitrypsin
#11357
middle Confidence
Subject:
SCTATs
(Tumor type)
→
feature
→
Object:
rosette_like_structures
(Histological characteristics)
Original: SCTATs#feature#highly cellular aspirates forming rosette-like structures
#11356
middle Confidence
Subject:
SCTATs
(Tumor type)
→
feature
→
Object:
highly_cellular_aspirates
(Histological characteristics)
Original: SCTATs#feature#highly cellular aspirates forming rosette-like structures
#11355
middle Confidence
Subject:
Cytologic_findings
(Cytological characteristics)
→
describe
→
Object:
paratracheal_metastasis
(Disease phenotype)
Original: Cytologic findings#describe#paratracheal metastasis from malignant SCTAT
#11352
middle Confidence
Subject:
left_testis
(organ)
→
has
→
Object:
well-demarcated_tumor
(Tumor tissue)
Original: left testis#has#a well-demarcated tumor diagnostic of seminoma
#11349
middle Confidence
Subject:
64-year-old_white_female_patient
(patient)
→
presented_with
→
Object:
Leukocytosis
(Clinical symptoms)
Original: 64-year-old white female patient#presented with#symptomatic anemia/ thrombocytopenia/ and leukocytosis
#11348
middle Confidence
Subject:
64-year-old_white_female_patient
(patient)
→
presented_with
→
Object:
thrombocytopenia
(Clinical symptoms)
Original: 64-year-old white female patient#presented with#symptomatic anemia/ thrombocytopenia/ and leukocytosis
#11347
middle Confidence
Subject:
64-year-old_white_female_patient
(patient)
→
presented_with
→
Object:
symptomatic_anemia
(Clinical symptoms)
Original: 64-year-old white female patient#presented with#symptomatic anemia/ thrombocytopenia/ and leukocytosis
#11338
middle Confidence
Subject:
schwannoma
(Tumor type)
→
are_compared_with
→
Object:
low_grade_spindle_cell_lesions
(Benign tumors)
Original: 58 schwannomas#are compared with#98 benign and low-grade spindle cell lesions
#11337
middle Confidence
Subject:
schwannoma
(Tumor type)
→
are_compared_with
→
Object:
benign_spindle_cell_lesions
(Benign tumors)
Original: 58 schwannomas#are compared with#98 benign and low-grade spindle cell lesions
#11324
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
NSE
(Protein markers)
Original: tumor cells and normal centroacinar cells#stain positive for#alpha-antitrypsin (alpha-AT)/ CD10/ cyclin D1/ and NSE
#11323
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
cyclin_D1
(Protein markers)
Original: tumor cells and normal centroacinar cells#stain positive for#alpha-antitrypsin (alpha-AT)/ CD10/ cyclin D1/ and NSE
#11322
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
CD10
(Protein markers)
Original: tumor cells and normal centroacinar cells#stain positive for#alpha-antitrypsin (alpha-AT)/ CD10/ cyclin D1/ and NSE
#11321
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
alpha-antitrypsin
(Protein markers)
Original: tumor cells and normal centroacinar cells#stain positive for#alpha-antitrypsin (alpha-AT)/ CD10/ cyclin D1/ and NSE
#11320
middle Confidence
Subject:
tumors
(Tumor tissue)
→
stain_positive_for
→
Object:
pseudo-smooth_muscle_actin
(Protein markers)
Original: tumors#stain positive for#�?smooth muscle actin
#11319
middle Confidence
Subject:
uterine_cytologic_examination
(Cytology)
→
revealed
→
Object:
large_cells_in_noncohesive_pattern
(Cell morphology)
Original: uterine cytologic examination#revealed#large cells distributed in a noncohesive pattern
#11318
middle Confidence
Subject:
cytomorphologic_characteristics
(Cell morphology)
→
included
→
Object:
three-dimensional_fragments_of_columnar_epithelium
(Cell morphology)
Original: cytomorphologic characteristics#included#large crowded sheets and three-dimensional fragments of columnar epithelium
#11317
middle Confidence
Subject:
cytomorphologic_characteristics
(Cell morphology)
→
included
→
Object:
large_crowded_sheets
(Cell morphology)
Original: cytomorphologic characteristics#included#large crowded sheets and three-dimensional fragments of columnar epithelium
#11316
middle Confidence
Subject:
aspirate
(Sample Type)
→
revealed
→
Object:
oncocytic_cells
(Cell Type)
Original: aspirate#revealed#cells with moderately abundant oncocytic cytoplasm
#11315
middle Confidence
Subject:
nuclei
(Cell structure)
→
show
→
Object:
monotonous_with_fine_chromatin
(Cell morphology)
Original: nuclei#were#monotonous with fine chromatin
#11314
middle Confidence
Subject:
cytologic_findings
(Cell morphology)
→
includes
→
Object:
cohesive_clusters_of_round_uniform_cells
(Cell morphology)
Original: cytologic findings#include#cohesive clusters of round/ uniform cells
#11313
middle Confidence
Subject:
smear_pattern
(Cell morphology)
→
shows
→
Object:
acute_inflammatory_background
(Cellular Processes)
Original: smear pattern#had#acute inflammatory background
#11310
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show_varied_histologic_organization
→
Object:
pleomorphic_tumor_structure
(Organizational Structure)
Original: histologic organization#varied from#normal to tubule-like structures to pleomorphic tumor cells
#11302
middle Confidence
Subject:
Carcinoma
(Neoplastic diseases)
→
shows_focal_positive_for
→
Object:
Cytokeratin_18
(protein)
Original: Immunohistological positivity of carcinoma#concerned#S-100 protein/ slightly CEA/ focally cytokeratin 7 and 18
#11301
middle Confidence
Subject:
Carcinoma
(Neoplastic diseases)
→
shows_focal_positive_for
→
Object:
Cytokeratin_7
(protein)
Original: Immunohistological positivity of carcinoma#concerned#S-100 protein/ slightly CEA/ focally cytokeratin 7 and 18
#11300
middle Confidence
Subject:
Carcinoma
(Neoplastic diseases)
→
shows_slightly_positive_for
→
Object:
CEA
(protein)
Original: Immunohistological positivity of carcinoma#concerned#S-100 protein/ slightly CEA/ focally cytokeratin 7 and 18
#11296
middle Confidence
Subject:
histological_specimens
(Tissue specimens)
→
were_checked_for
→
Object:
atypical_spermatogonia
(Germ cells)
Original: Histological specimens#were checked for#atypical spermatogonia
#11286
middle Confidence
Subject:
endometrial_cytology
(Cytological analysis)
→
compared_with
→
Object:
endometrioid_adenocarcinoma
(Disease subtype)
Original: Cytological findings of endometrium#were compared between#UPSC and endometrioid adenocarcinoma
#11285
middle Confidence
Subject:
endometrial_cytology
(Cytological analysis)
→
compared_with
→
Object:
UPSC
(Disease subtype)
Original: Cytological findings of endometrium#were compared between#UPSC and endometrioid adenocarcinoma
#11278
middle Confidence
Subject:
reparative_regenerative_changes_in_IBD
(Organizational response)
→
are
→
Object:
pitfalls_in_cytology_diagnosis_of_malignancy
(Diagnostic Mistakes)
Original: reparative/regenerative changes in IBD#are#pitfalls in cytology diagnosis of malignancy
#11275
middle Confidence
Subject:
Monoclonal_plasma_cell
(Cell Type)
→
shows
→
Object:
abnormal_phenotype
(Cell phenotype)
Original: Monoclonal plasma cell#had#abnormal phenotype consistent with plasma cell tumor
#11272
middle Confidence
Subject:
increased_nuclear_cytoplasmic_ratio
(Nuclear-cytoplasmic ratio)
→
classified_as
→
Object:
criteria_in_cervical_smears
(Diagnostic criteria)
Original: increased nuclear/cytoplasmic ratio#is classified as#criteria in cervical smears
#11271
middle Confidence
Subject:
irregular_nuclear_membranes
(Nuclear morphology)
→
classified_as
→
Object:
criteria_in_cervical_smears
(Diagnostic criteria)
Original: irregular nuclear membranes#are classified as#criteria in cervical smears
#11270
middle Confidence
Subject:
uterine_cytologic_examination
(Cytology)
→
used_for
→
Object:
IVL
(disease)
Original: uterine cytologic examinations#are used for#diagnosis of IVL
#11269
middle Confidence
Subject:
smooth_muscle_actin_expression
(Protein expression)
→
is_detected_by
→
Object:
Immunohistochemistry
(Diagnostic techniques)
Original: Immunohistochemistry#revealed#strong diffuse vimentin and smooth muscle actin positivity
#11268
middle Confidence
Subject:
vimentin_expression
(Protein expression)
→
is_detected_by
→
Object:
Immunohistochemistry
(Diagnostic techniques)
Original: Immunohistochemistry#revealed#strong diffuse vimentin and smooth muscle actin positivity
#11244
middle Confidence
Subject:
SMA
(Smooth muscle actin)
→
is_detected_by
→
Object:
Immunohistochemistry
(Detection Technology)
Original: Immunohistochemical studies#were positive for#GFAP/ vimentin/ S-100/ CK/ EMA/ and SMA
#11243
middle Confidence
Subject:
EMA
(Epithelial membrane antigen)
→
is_detected_by
→
Object:
Immunohistochemistry
(Detection Technology)
Original: Immunohistochemical studies#were positive for#GFAP/ vimentin/ S-100/ CK/ EMA/ and SMA
#11242
middle Confidence
Subject:
CK
(Cytokeratin)
→
is_detected_by
→
Object:
Immunohistochemistry
(Detection Technology)
Original: Immunohistochemical studies#were positive for#GFAP/ vimentin/ S-100/ CK/ EMA/ and SMA
#11241
middle Confidence
Subject:
S-100
(Calcium Binding Protein)
→
is_detected_by
→
Object:
Immunohistochemistry
(Detection Technology)
Original: Immunohistochemical studies#were positive for#GFAP/ vimentin/ S-100/ CK/ EMA/ and SMA
#11240
middle Confidence
Subject:
vimentin
(Intermediate filament protein)
→
is_detected_by
→
Object:
Immunohistochemistry
(Detection Technology)
Original: Immunohistochemical studies#were positive for#GFAP/ vimentin/ S-100/ CK/ EMA/ and SMA
#11239
middle Confidence
Subject:
GFAP
(Intermediate filament protein)
→
is_detected_by
→
Object:
Immunohistochemistry
(Detection Technology)
Original: Immunohistochemical studies#were positive for#GFAP/ vimentin/ S-100/ CK/ EMA/ and SMA
#11238
middle Confidence
Subject:
RCC
(Tumor type)
→
shows_no_expression_of
→
Object:
keratin_34_beta_E12
(Cytokeratin)
Original: RCC#was not positive for#keratin detectable by antibody 34 beta E12
#11232
middle Confidence
Subject:
subtle_histologic_clues
(Histopathological characteristics)
→
suggest
→
Object:
possibility_of_metastatic_carcinoma
(Disease phenotype)
Original: Subtle histologic clues#suggest#the possibility of metastatic carcinoma
#11216
middle Confidence
Subject:
cells
(cell)
→
show
→
Object:
desmosomes_ultrastructurally
(Cell junction structure)
Original: cells#are positive for#CD21/ CD35/ and desmosomes ultrastructurally
#11194
middle Confidence
Subject:
hepatocytes
(Hepatocytes)
→
are_associated_with
→
Object:
cholangiocellular_carcinoma
(Tumor diseases)
Original: Clusters of epithelial cells#intermix with#normal hepatocytes/ indicative of metastatic or cholangiocellular carcinoma
#11193
middle Confidence
Subject:
hepatocytes
(Hepatocytes)
→
are_associated_with
→
Object:
metastatic_carcinoma
(Tumor diseases)
Original: Clusters of epithelial cells#intermix with#normal hepatocytes/ indicative of metastatic or cholangiocellular carcinoma
#11192
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_associated_with
→
Object:
cholangiocellular_carcinoma
(Tumor diseases)
Original: Clusters of epithelial cells#intermix with#normal hepatocytes/ indicative of metastatic or cholangiocellular carcinoma
#11190
middle Confidence
Subject:
difficult_differential_diagnosis
(Diagnostic Process)
→
with
→
Object:
pleomorphic_adenoma
(Tumor diseases)
Original: Cytomorphology#presents#a difficult differential diagnosis with pleomorphic adenoma
#11189
middle Confidence
Subject:
highly_cellular_smears
(Cytological phenotype)
→
contain
→
Object:
small_slightly_atypical_cells
(Cell phenotype)
Original: Aspirate#yields#highly cellular smears with small/ slightly atypical cells in multilayered groups
#11178
middle Confidence
Subject:
lymphoid_cells
(Lymphocytes)
→
were_positive_for
→
Object:
CD3
(T cell markers)
Original: Lymphoid cells#were positive for#CD3 but negative for CD21/ kappa/ and lambda immunoglobulin light chains
#11159
middle Confidence
Subject:
tumor
(Tumor)
→
revealed
→
Object:
prominent_nucleoli
(Nucleolar morphology)
Original: tumor#revealed#clusters of large pleomorphic cells with vesicular nuclei and prominent nucleoli
#11158
middle Confidence
Subject:
tumor
(Tumor)
→
revealed
→
Object:
vesicular_nuclei
(Nuclear morphology)
Original: tumor#revealed#clusters of large pleomorphic cells with vesicular nuclei and prominent nucleoli
#11157
middle Confidence
Subject:
tumor
(Tumor)
→
revealed
→
Object:
clusters_of_large_pleomorphic_cells
(Tumor cell morphology)
Original: tumor#revealed#clusters of large pleomorphic cells with vesicular nuclei and prominent nucleoli
#11156
middle Confidence
Subject:
tumor
(Tumor)
→
was_composed_of
→
Object:
severely_atypical_melanocytoid_cells
(Tumor cell morphology)
Original: tumor#was composed of#severely atypical melanocytoid cells
#11155
middle Confidence
Subject:
tumor
(Tumor)
→
consisted_of
→
Object:
prominent_nucleoli
(Nucleolar morphology)
Original: Tumor#consisted of#solid sheets of round and polygonal cells with homogeneously eosinophilic cytoplasm and pleomorphic nuclei with prominent nucleoli
#11154
middle Confidence
Subject:
tumor
(Tumor)
→
consisted_of
→
Object:
pleomorphic_nuclei
(Nuclear morphology)
Original: Tumor#consisted of#solid sheets of round and polygonal cells with homogeneously eosinophilic cytoplasm and pleomorphic nuclei with prominent nucleoli
#11153
middle Confidence
Subject:
tumor
(Tumor)
→
consisted_of
→
Object:
homogeneously_eosinophilic_cytoplasm
(Cytoplasmic morphology)
Original: Tumor#consisted of#solid sheets of round and polygonal cells with homogeneously eosinophilic cytoplasm and pleomorphic nuclei with prominent nucleoli
#11152
middle Confidence
Subject:
tumor
(Tumor)
→
consisted_of
→
Object:
solid_sheets_of_polygonal_cells
(Tumor cell morphology)
Original: Tumor#consisted of#solid sheets of round and polygonal cells with homogeneously eosinophilic cytoplasm and pleomorphic nuclei with prominent nucleoli
#11151
middle Confidence
Subject:
tumor
(Tumor)
→
consisted_of
→
Object:
solid_sheets_of_round_cells
(Tumor cell morphology)
Original: Tumor#consisted of#solid sheets of round and polygonal cells with homogeneously eosinophilic cytoplasm and pleomorphic nuclei with prominent nucleoli
#11150
middle Confidence
Subject:
tumor
(Tumor)
→
was_composed_of
→
Object:
small_variable_amounts_of_indistinct_pink_cytoplasm
(Cytoplasmic morphology)
Original: Tumor#was composed of#small cells with round to oval dark nuclei/ clumped chromatin/ one to two nucleoli/ and small/ variable amounts of indistinct pink cytoplasm
#11149
middle Confidence
Subject:
tumor
(Tumor)
→
was_composed_of
→
Object:
one_to_two_nucleoli
(Nucleolar morphology)
Original: Tumor#was composed of#small cells with round to oval dark nuclei/ clumped chromatin/ one to two nucleoli/ and small/ variable amounts of indistinct pink cytoplasm
#11148
middle Confidence
Subject:
tumor
(Tumor)
→
was_composed_of
→
Object:
clumped_chromatin
(Chromatin state)
Original: Tumor#was composed of#small cells with round to oval dark nuclei/ clumped chromatin/ one to two nucleoli/ and small/ variable amounts of indistinct pink cytoplasm
#11147
middle Confidence
Subject:
tumor
(Tumor)
→
was_composed_of
→
Object:
small_cells_with_round_to_oval_dark_nuclei
(Tumor cell morphology)
Original: Tumor#was composed of#small cells with round to oval dark nuclei/ clumped chromatin/ one to two nucleoli/ and small/ variable amounts of indistinct pink cytoplasm
#11144
middle Confidence
Subject:
EPSC
(Cytological detection technology)
→
reveals
→
Object:
large_tumor_cells_with_prominent_nucleoli
(Tumor cell morphology)
Original: EPSC#reveals#large tumor cells with prominent nucleoli
#11137
middle Confidence
Subject:
pathologists
(Medical professionals)
→
need_to_recognize
→
Object:
cytomorphologic_features_of_AT/RT_in_CSF
(Cell morphology)
Original: Pathologists#need to recognize#the cytomorphologic features of AT/RT in CSF to determine prognosis and disease progression
#11125
middle Confidence
Subject:
Fine-needle_aspiration_biopsy
(Diagnostic techniques)
→
was_performed_on
→
Object:
FA_patients
(Disease patients)
Original: Fine-needle aspiration biopsy#was performed on#4 women with FA
#11124
middle Confidence
Subject:
Fine-needle_aspiration_cytology
(Diagnostic techniques)
→
revealed
→
Object:
glycogen-containing_cells
(Cell Type)
Original: Fine-needle aspiration cytology#revealed#a dual population of cells including polyhedral eosinophilic cells and glycogen-containing cells
#11123
middle Confidence
Subject:
Fine-needle_aspiration_cytology
(Diagnostic techniques)
→
revealed
→
Object:
polyhedral_eosinophilic_cells
(Cell Type)
Original: Fine-needle aspiration cytology#revealed#a dual population of cells including polyhedral eosinophilic cells and glycogen-containing cells
#11122
middle Confidence
Subject:
retinoblastoma_tumor
(Tumor tissue)
→
shows
→
Object:
typical_histologic_features
(Histological characteristics)
Original: Tumors#showed#typical histologic features of retinoblastoma with primitive round cells
#11121
middle Confidence
Subject:
retinoblastoma_tumor
(Tumor tissue)
→
shows
→
Object:
primitive_round_cells
(Cell morphology)
Original: Tumors#showed#typical histologic features of retinoblastoma with primitive round cells
#11082
middle Confidence
Subject:
undifferentiated_cell
(Tumor cells)
→
shows
→
Object:
numerous_mitoses
(Cell division)
Original: tumors#show#syncytial growth pattern of undifferentiated cells with ill-defined cytoplasmic borders/ prominent nucleoli/ and numerous mitoses
#11081
middle Confidence
Subject:
undifferentiated_cell
(Tumor cells)
→
shows
→
Object:
prominent_nucleolus
(Nucleolus)
Original: tumors#show#syncytial growth pattern of undifferentiated cells with ill-defined cytoplasmic borders/ prominent nucleoli/ and numerous mitoses
#11080
middle Confidence
Subject:
undifferentiated_cell
(Tumor cells)
→
shows
→
Object:
ill-defined_cytoplasmic_borders
(Cytoplasm)
Original: tumors#show#syncytial growth pattern of undifferentiated cells with ill-defined cytoplasmic borders/ prominent nucleoli/ and numerous mitoses
#11079
middle Confidence
Subject:
undifferentiated_cell
(Tumor cells)
→
shows
→
Object:
syncytial_growth_pattern
(Cell growth pattern)
Original: tumors#show#syncytial growth pattern of undifferentiated cells with ill-defined cytoplasmic borders/ prominent nucleoli/ and numerous mitoses
#11078
middle Confidence
Subject:
epithelioid_cell
(Tumor cells)
→
shows
→
Object:
prominent_nucleolus
(Nucleolus)
Original: all tumors#show#diffuse sheets of mildly dyscohesive/ relatively monotonous/ and undifferentiated epithelioid cells with prominent nucleoli
#11077
middle Confidence
Subject:
eosinophilic_cell
(Tumor cells)
→
contains
→
Object:
prominent_nucleolus
(Nucleolus)
Original: tumor cells#contain#large eosinophilic cells with vesicular nuclei containing prominent nucleoli
#11076
middle Confidence
Subject:
eosinophilic_cell
(Tumor cells)
→
contains
→
Object:
vesicular_nucleus
(Nucleus)
Original: tumor cells#contain#large eosinophilic cells with vesicular nuclei containing prominent nucleoli
#11075
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
is_characterized_by
→
Object:
inapparent_cytoplasm
(Cytoplasm)
Original: tumor cells#are characterized by#small size/ fine chromatin/ inconspicuous nucleoli/ and inapparent cytoplasm
#11074
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
is_characterized_by
→
Object:
inconspicuous_nucleolus
(Nucleolus)
Original: tumor cells#are characterized by#small size/ fine chromatin/ inconspicuous nucleoli/ and inapparent cytoplasm
#11073
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
is_characterized_by
→
Object:
fine_chromatin
(Chromatin structure)
Original: tumor cells#are characterized by#small size/ fine chromatin/ inconspicuous nucleoli/ and inapparent cytoplasm
#11072
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
is_characterized_by
→
Object:
small_size
(Cell morphology)
Original: tumor cells#are characterized by#small size/ fine chromatin/ inconspicuous nucleoli/ and inapparent cytoplasm
#11071
middle Confidence
Subject:
large_cell
(Tumor cells)
→
contains
→
Object:
voluminous_nucleolus
(Nucleolus)
Original: medulloblastoma#contains#hypercellular sheets with sparse large cells with eosinophilic cytoplasm and round nuclei containing voluminous nucleoli
#11070
middle Confidence
Subject:
large_cell
(Tumor cells)
→
is_characterized_by
→
Object:
round_nucleus
(Nucleus)
Original: medulloblastoma#contains#hypercellular sheets with sparse large cells with eosinophilic cytoplasm and round nuclei containing voluminous nucleoli
#11069
middle Confidence
Subject:
large_cell
(Tumor cells)
→
is_characterized_by
→
Object:
eosinophilic_cytoplasm
(Cytoplasm)
Original: medulloblastoma#contains#hypercellular sheets with sparse large cells with eosinophilic cytoplasm and round nuclei containing voluminous nucleoli
#11068
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
contains
→
Object:
prominent_nucleolus
(Nucleolus)
Original: tumor cells#contain#round and vesicular nuclei with prominent nucleoli
#11067
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
contains
→
Object:
round_vesicular_nucleus
(Nucleus)
Original: tumor cells#contain#round and vesicular nuclei with prominent nucleoli
#11066
middle Confidence
Subject:
nucleus
(Nucleus)
→
exhibits
→
Object:
inconspicuous_nucleolus
(Nucleolus)
Original: nuclei#exhibit#a finely granular chromatin pattern with or without inconspicuous nucleoli
#11065
middle Confidence
Subject:
nucleus
(Nucleus)
→
exhibits
→
Object:
finely_granular_chromatin_pattern
(Chromatin structure)
Original: nuclei#exhibit#a finely granular chromatin pattern with or without inconspicuous nucleoli
#11064
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
contains
→
Object:
ill-defined_filmy_cytoplasm
(Cytoplasm)
Original: tumor cells#contain#round/ oval/ or spindle-shaped nuclei with variable and ill-defined filmy cytoplasm
#11063
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
contains
→
Object:
spindle-shaped_nucleus
(Nucleus)
Original: tumor cells#contain#round/ oval/ or spindle-shaped nuclei with variable and ill-defined filmy cytoplasm
#11062
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
contains
→
Object:
oval_nucleus
(Nucleus)
Original: tumor cells#contain#round/ oval/ or spindle-shaped nuclei with variable and ill-defined filmy cytoplasm
#11061
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
contains
→
Object:
round_nucleus
(Nucleus)
Original: tumor cells#contain#round/ oval/ or spindle-shaped nuclei with variable and ill-defined filmy cytoplasm
#11060
middle Confidence
Subject:
polygonal_cell
(Tumor cells)
→
contains
→
Object:
eosinophilic_inclusion
(Intracellular inclusion bodies)
Original: Malignant rhabdoid tumors#are characterized by#sheets of large polygonal cells with abundant cytoplasm containing eosinophilic inclusions
#11059
middle Confidence
Subject:
polygonal_cell
(Tumor cells)
→
is_characterized_by
→
Object:
abundant_cytoplasm
(Cytoplasm)
Original: Malignant rhabdoid tumors#are characterized by#sheets of large polygonal cells with abundant cytoplasm containing eosinophilic inclusions
#11058
middle Confidence
Subject:
rhabdoid_cell
(Tumor cells)
→
is_characterized_by
→
Object:
abundant_hyaline_cytoplasm
(Cytoplasm)
Original: Rhabdoid cells#are characterized by#plump shape with abundant eosinophilic fibrillary to hyaline cytoplasm
#11057
middle Confidence
Subject:
rhabdoid_cell
(Tumor cells)
→
is_characterized_by
→
Object:
abundant_eosinophilic_fibrillary_cytoplasm
(Cytoplasm)
Original: Rhabdoid cells#are characterized by#plump shape with abundant eosinophilic fibrillary to hyaline cytoplasm
#11056
middle Confidence
Subject:
rhabdoid_cell
(Tumor cells)
→
is_characterized_by
→
Object:
plump_shape
(Cell morphology)
Original: Rhabdoid cells#are characterized by#plump shape with abundant eosinophilic fibrillary to hyaline cytoplasm
#11055
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
contains
→
Object:
conspicuous_nucleolus
(Nucleolus)
Original: tumor cells#contain#large irregular-shaped nuclei with conspicuous nucleoli
#11054
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
contains
→
Object:
large_irregular-shaped_nucleus
(Nucleus)
Original: tumor cells#contain#large irregular-shaped nuclei with conspicuous nucleoli
#11053
middle Confidence
Subject:
Von_Hippel-Lindau_syndrome
(Genetic disorders)
→
was_found_to_have
→
Object:
renal_cyst
(Cyst)
Original: 47-year-old woman with VHL#was found to have#a mass in the pancreatic tail and two masses in the right kidney with two cysts
#11052
middle Confidence
Subject:
Von_Hippel-Lindau_syndrome
(Genetic disorders)
→
was_found_to_have
→
Object:
renal_mass
(Tumor)
Original: 47-year-old woman with VHL#was found to have#a mass in the pancreatic tail and two masses in the right kidney with two cysts
#11051
middle Confidence
Subject:
Von_Hippel-Lindau_syndrome
(Genetic disorders)
→
was_found_to_have
→
Object:
pancreatic_mass
(Tumor)
Original: 47-year-old woman with VHL#was found to have#a mass in the pancreatic tail and two masses in the right kidney with two cysts
#11038
middle Confidence
Subject:
neoplasms
(Tumor)
→
are_characterized_by
→
Object:
spindle_cells
(Cell Type)
Original: Neoplasms#are characterized by#pleomorphic giant or spindle cells with multilobulated nuclei
#11037
middle Confidence
Subject:
neoplasms
(Tumor)
→
are_characterized_by
→
Object:
pleomorphic_giant_cells
(Cell Type)
Original: Neoplasms#are characterized by#pleomorphic giant or spindle cells with multilobulated nuclei
#11036
middle Confidence
Subject:
pilomatrixoma
(Benign tumors)
→
is_a
→
Object:
pitfall_in_aspiration_cytology
(Diagnostic Pitfalls)
Original: Pilomatrixoma#is a#pitfall in the aspiration cytology of skin tumors
#11014
middle Confidence
Subject:
histological_diagnosis
(Diagnostic Process)
→
revealed
→
Object:
mastopathy
(Benign breast lesions)
Original: Histological diagnosis#revealed#gynaecomastia in 13 cases and mastopathy in 1 case
#11013
middle Confidence
Subject:
histological_diagnosis
(Diagnostic Process)
→
revealed
→
Object:
gynaecomastia
(Benign breast lesions)
Original: Histological diagnosis#revealed#gynaecomastia in 13 cases and mastopathy in 1 case
#11012
middle Confidence
Subject:
cytologic_differential_diagnosis
(Diagnostic Process)
→
gives
→
Object:
tubal_metaplasia
(Non-neoplastic lesions)
Original: Cytologic differential diagnosis#gives#clear cell carcinoma/ microglandular hyperplasia/ diffuse laminar glandular hyperplasia/ tubal metaplasia/ and adenocarcinoma
#11011
middle Confidence
Subject:
cytologic_differential_diagnosis
(Diagnostic Process)
→
gives
→
Object:
diffuse_laminar_glandular_hyperplasia
(Non-neoplastic lesions)
Original: Cytologic differential diagnosis#gives#clear cell carcinoma/ microglandular hyperplasia/ diffuse laminar glandular hyperplasia/ tubal metaplasia/ and adenocarcinoma
#11010
middle Confidence
Subject:
cytologic_differential_diagnosis
(Diagnostic Process)
→
gives
→
Object:
microglandular_hyperplasia
(Non-neoplastic lesions)
Original: Cytologic differential diagnosis#gives#clear cell carcinoma/ microglandular hyperplasia/ diffuse laminar glandular hyperplasia/ tubal metaplasia/ and adenocarcinoma
#11002
middle Confidence
Subject:
atypical_apocrine_adenosis
(Abnormal gland structure)
→
is_defined_as
→
Object:
nuclear_area_variation
(Nuclear morphology)
Original: atypical apocrine adenosis#is defined as#enlarged nucleoli and nuclear area variation
#11001
middle Confidence
Subject:
atypical_apocrine_adenosis
(Abnormal gland structure)
→
is_defined_as
→
Object:
enlarged_nucleoli
(Nuclear morphology)
Original: atypical apocrine adenosis#is defined as#enlarged nucleoli and nuclear area variation
#11000
middle Confidence
Subject:
study
(Research)
→
investigated
→
Object:
clinicopathologic_features_of_EMFS
(Disease phenotype)
Original: study#investigated#clinicopathologic features of epitheioid myxofibrosarcoma
#10998
middle Confidence
Subject:
clear_cell_adenocarcinoma
(Tumor type)
→
is_associated_with
→
Object:
large_nucleoli_in_atypical_cells
(Nucleolar characteristics)
Original: clear cell adenocarcinoma#is associated with#large nucleoli in atypical cells
#10995
middle Confidence
Subject:
cytologic_diagnosis
(Cytological diagnosis)
→
achieved_in
→
Object:
ambulatory_patient
(patient)
Original: cytologic diagnosis#is achieved in#92% of screened ambulatory patients with no complications observed
#10984
middle Confidence
Subject:
SPC_cytological_features
(Cytological characteristics)
→
coexist_with
→
Object:
benign_features
(Cytological characteristics)
Original: SPC cytological features#coexist with#malignant and benign features
#10983
middle Confidence
Subject:
SPC_cytological_features
(Cytological characteristics)
→
coexist_with
→
Object:
malignant_features
(Cytological characteristics)
Original: SPC cytological features#coexist with#malignant and benign features
#10982
middle Confidence
Subject:
Malignant_cytological_features
(Cytological characteristics)
→
are_characterized_by
→
Object:
severe_overcrowding_cells
(Cytological characteristics)
Original: Malignant cytological features#are characterized by#hypercellularity and severe overcrowding cells
#10981
middle Confidence
Subject:
Malignant_cytological_features
(Cytological characteristics)
→
are_characterized_by
→
Object:
hypercellularity
(Cytological characteristics)
Original: Malignant cytological features#are characterized by#hypercellularity and severe overcrowding cells
#10979
middle Confidence
Subject:
Nuclear_pseudostratification
(Nuclear structure)
→
Occupies
→
Object:
basal_half_of_cryptal_cells
(Cell structure)
Original: Nuclear pseudostratification#occupies#more than the basal half of the cryptal cells in high-grade dysplasia
#10978
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
contain
→
Object:
prominent_nucleoli
(Nuclear components)
Original: Neoplastic cells#contain#prominent nucleoli
#10977
middle Confidence
Subject:
cells_of_hepatosplenic_T-cell_lymphoma
(Tumor cells)
→
were
→
Object:
homogeneous_medium_size_with_pale_cytoplasm
(Cell morphology)
Original: Cells of hepatosplenic T-cell lymphoma#were#homogeneous/ medium in size with pale cytoplasm
#10976
middle Confidence
Subject:
cytological_features
(Cytological characteristics)
→
differentiation
→
Object:
low-grade_urothelial_carcinoma_cells
(Tumor cells)
Original: Cytological features#differentiate#reactive renal tubular cells from low-grade urothelial carcinoma cells
#10975
middle Confidence
Subject:
cytological_features
(Cytological characteristics)
→
differentiation
→
Object:
reactive_renal_tubular_cells
(Cell Type)
Original: Cytological features#differentiate#reactive renal tubular cells from low-grade urothelial carcinoma cells
#10974
middle Confidence
Subject:
ICC
(Immunocytochemistry)
→
shows
→
Object:
CK20_positive
(Protein expression)
Original: ICC#showed#LCA negative/ Cytokeratin positive/ CD56 positive/ CK20 positive
#10973
middle Confidence
Subject:
ICC
(Immunocytochemistry)
→
shows
→
Object:
CD56_positive
(Protein expression)
Original: ICC#showed#LCA negative/ Cytokeratin positive/ CD56 positive/ CK20 positive
#10972
middle Confidence
Subject:
ICC
(Immunocytochemistry)
→
shows
→
Object:
Cytokeratin_positive
(Protein expression)
Original: ICC#showed#LCA negative/ Cytokeratin positive/ CD56 positive/ CK20 positive
#10971
middle Confidence
Subject:
ICC
(Immunocytochemistry)
→
shows
→
Object:
LCA_negative
(Protein expression)
Original: ICC#showed#LCA negative/ Cytokeratin positive/ CD56 positive/ CK20 positive
#10967
middle Confidence
Subject:
SDH-deficient_RCC_cytology
(Cytology test results)
→
shows
→
Object:
inconspicuous_nucleoli
(Inconspicuous nucleolus)
Original: SDH-deficient RCC cytology#shows#polygonal cells with vacuolated eosinophilic cytoplasm/ fine chromatin/ inconspicuous nucleoli
#10966
middle Confidence
Subject:
SDH-deficient_RCC_cytology
(Cytology test results)
→
shows
→
Object:
fine_chromatin
(Fine chromatin)
Original: SDH-deficient RCC cytology#shows#polygonal cells with vacuolated eosinophilic cytoplasm/ fine chromatin/ inconspicuous nucleoli
#10965
middle Confidence
Subject:
SDH-deficient_RCC_cytology
(Cytology test results)
→
shows
→
Object:
polygonal_cells_with_vacuolated_eosinophilic_cytoplasm
(Polygonal cells with vacuolated eosinophilic cytoplasm)
Original: SDH-deficient RCC cytology#shows#polygonal cells with vacuolated eosinophilic cytoplasm/ fine chromatin/ inconspicuous nucleoli
#10964
middle Confidence
Subject:
FNA_findings_of_ASPS
(Cytology test results)
→
include
→
Object:
cytoplasmic_zonation
(Cytoplasmic partitioning)
Original: FNA findings of ASPS#include#alveolar aggregates/ capillary networks/ eccentric nuclei with prominent nucleoli/ intranuclear vacuoles/ cytoplasmic zonation
#10963
middle Confidence
Subject:
FNA_findings_of_ASPS
(Cytology test results)
→
include
→
Object:
intranuclear_vacuoles
(Intranuclear vacuoles)
Original: FNA findings of ASPS#include#alveolar aggregates/ capillary networks/ eccentric nuclei with prominent nucleoli/ intranuclear vacuoles/ cytoplasmic zonation
#10962
middle Confidence
Subject:
FNA_findings_of_ASPS
(Cytology test results)
→
include
→
Object:
eccentric_nuclei_with_prominent_nucleoli
(Eccentric nucleus with prominent nucleolus)
Original: FNA findings of ASPS#include#alveolar aggregates/ capillary networks/ eccentric nuclei with prominent nucleoli/ intranuclear vacuoles/ cytoplasmic zonation
#10961
middle Confidence
Subject:
FNA_findings_of_ASPS
(Cytology test results)
→
include
→
Object:
capillary_networks
(Capillary network)
Original: FNA findings of ASPS#include#alveolar aggregates/ capillary networks/ eccentric nuclei with prominent nucleoli/ intranuclear vacuoles/ cytoplasmic zonation
#10960
middle Confidence
Subject:
FNA_findings_of_ASPS
(Cytology test results)
→
include
→
Object:
alveolar_aggregates
(Alveolar cell aggregates)
Original: FNA findings of ASPS#include#alveolar aggregates/ capillary networks/ eccentric nuclei with prominent nucleoli/ intranuclear vacuoles/ cytoplasmic zonation
#10924
middle Confidence
Subject:
AAH
(Pathological changes)
→
possesses
→
Object:
oval_to_irregular_nuclei_with_large_nucleoli
(Nuclear morphology)
Original: AAH#possessed#oval to irregular nuclei with large nucleoli
#10923
middle Confidence
Subject:
primary_oncocytic_thyroid_tumor
(Tumor type)
→
exhibits
→
Object:
large_cherry_red_nucleoli
(Nuclear morphology)
Original: Primary oncocytic thyroid tumors#exhibit#large cherry red nucleoli
#10911
middle Confidence
Subject:
psammoma_bodies
(Calcified bodies)
→
is_contained_in
→
Object:
tumor_cells
(Tumor cells)
Original: tumor cells#contain#psammoma bodies
#10910
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed_expression_of
→
Object:
CD34
(CD34antigen)
Original: Tumor cells#showed#a polyphenotypic expression including positivity for epithelial and mesenchymal markers
#10909
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed_expression_of
→
Object:
vimentin
(Vimentin)
Original: Tumor cells#showed#a polyphenotypic expression including positivity for epithelial and mesenchymal markers
#10908
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed_expression_of
→
Object:
EMA
(Epithelial membrane antigen)
Original: Tumor cells#showed#a polyphenotypic expression including positivity for epithelial and mesenchymal markers
#10907
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed_expression_of
→
Object:
CK7
(Cytokeratin)
Original: Tumor cells#showed#a polyphenotypic expression including positivity for epithelial and mesenchymal markers
#10906
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed_expression_of
→
Object:
cytokeratin_(CK)
(Cytokeratin)
Original: Tumor cells#showed#a polyphenotypic expression including positivity for epithelial and mesenchymal markers
#10860
middle Confidence
Subject:
small_round_cell_neoplasm
(Tumor type)
→
was_diagnosed_as
→
Object:
neuroendocrine_differentiation
(Differentiation characteristics)
Original: Tumor#was diagnosed as#a small round cell neoplasm with neuroendocrine differentiation
#10854
middle Confidence
Subject:
needle_biopsy
(Histological techniques)
→
showed
→
Object:
normal_respiratory_epithelium
(Epithelial cells)
Original: needle biopsy#showed#normal respiratory epithelium
#10840
middle Confidence
Subject:
fibrous_stroma_including_CAFs
(Tissue matrix)
→
was_investigated_in
→
Object:
benign_cases
(Benign cases)
Original: prevalence of fibrous stroma including CAFs#was investigated in#PDAC cases and benign cases
#10839
middle Confidence
Subject:
fibrous_stroma_including_CAFs
(Tissue matrix)
→
was_investigated_in
→
Object:
PDAC_cases
(Disease Cases)
Original: prevalence of fibrous stroma including CAFs#was investigated in#PDAC cases and benign cases
#10835
middle Confidence
Subject:
SpCCs
(Tumor cell subtype)
→
contain
→
Object:
neoplastic_glands_similar_to_adenocarcinoma
(Cell structure)
Original: SpCCs#contain#neoplastic glands similar to adenocarcinoma
#10826
middle Confidence
Subject:
patients
(patient)
→
are_identified_with
→
Object:
high_grade_carcinoma_in_urinary_cytology
(Disease phenotype)
Original: 250 patients#are identified with#high-grade carcinoma in urinary cytology
#10815
middle Confidence
Subject:
recognition of histologic variants
(Identification of histological variants)
→
is_important_in
→
Object:
diagnostic assessment of tumors
(Tumor diagnostic evaluation)
Original: recognition of histologic variants#is important in#diagnostic assessment of tumors
#10802
middle Confidence
Subject:
tumors
(Tumor tissue)
→
were_characterized_by
→
Object:
cellular_proliferation_of_small_cells_with_round_nuclei_and_inconspicuous_nucleoli
(Cell morphology)
Original: tumors#were characterized by#a cellular proliferation of small cells with round nuclei and inconspicuous nucleoli
#10801
middle Confidence
Subject:
cytologic_examination
(Cytology)
→
showed
→
Object:
single_cells_of_spindle_morphology
(Cell morphology)
Original: cytologic examination#showed#a population of single cells of predominantly spindle morphology
#10798
middle Confidence
Subject:
WDPM
(Tumor type)
→
has
→
Object:
distinct_pathological_features
(Pathological characteristics)
Original: WDPM#has#distinct pathological features
#10796
middle Confidence
Subject:
MRI
(Medical imaging technology)
→
is_primary_modality_for
→
Object:
diagnosis_of_FLC
(Disease diagnosis)
Original: ultrasound/ CT/ and MRI#are the primary modalities for#diagnosis of FLC
#10795
middle Confidence
Subject:
CT
(Medical imaging technology)
→
is_primary_modality_for
→
Object:
diagnosis_of_FLC
(Disease diagnosis)
Original: ultrasound/ CT/ and MRI#are the primary modalities for#diagnosis of FLC
#10794
middle Confidence
Subject:
ultrasound
(Medical imaging technology)
→
is_primary_modality_for
→
Object:
diagnosis_of_FLC
(Disease diagnosis)
Original: ultrasound/ CT/ and MRI#are the primary modalities for#diagnosis of FLC
#10779
middle Confidence
Subject:
AgNOR_counts
(Nucleolus-associated organic silver stain count)
→
were_lower_in
→
Object:
dentigerous_cyst
(Disease phenotype)
Original: AgNOR counts#were higher in#KCOT and ameloblastoma than dentigerous cyst
#10766
middle Confidence
Subject:
CD5
(Immune differentiation antigens)
→
is_expressed_in
→
Object:
B-cell_tumors
(Tumor cells)
Original: All tumors#demonstrated#a consistent immunophenotype of B-cell lineage/ surface immunoglobulin positivity/ and CD5 antigen expression
#10765
middle Confidence
Subject:
CD5
(Immune differentiation antigens)
→
is_expressed_in
→
Object:
Immature/blastic_B-lineage_lymphoid_cells
(Immune cells)
Original: Six patients#had#blood and bone marrow manifestations of morphologically immature or blastic B-lineage lymphoid cells expressing CD5 antigen
#10764
middle Confidence
Subject:
CD5
(Immune differentiation antigens)
→
is_expressed_in
→
Object:
B-lineage_lymphoid_cells
(Immune cells)
Original: Six patients#had#blood and bone marrow manifestations of morphologically immature or blastic B-lineage lymphoid cells expressing CD5 antigen
#10668
middle Confidence
Subject:
nucleolar_morphology
(Cell structure)
→
is_marker_of
→
Object:
differentiation_process
(Cellular Processes)
Original: Nucleolar RNA concentration and morphology#are sensitive markers of#differentiation process
#10667
middle Confidence
Subject:
nucleolar_RNA_concentration
(Cell components)
→
is_marker_of
→
Object:
differentiation_process
(Cellular Processes)
Original: Nucleolar RNA concentration and morphology#are sensitive markers of#differentiation process
#10662
middle Confidence
Subject:
Brush_cytology
(Brush Cytology)
→
helps_in
→
Object:
early_mouth_cancer_detection
(Oral Cancer Early Detection)
Original: Brush cytology#helps in#early mouth cancer detection by counting AgNORs
#10660
middle Confidence
Subject:
34Beta12
(Cytoskeletal proteins)
→
is_expressed_at
→
Object:
foamy_gland_carcinoma
(Tumor type)
Original: Immunohistochemical markers in foamy gland carcinoma#are expressed at#90.1% for p63/ 90.6% for 34Beta12/ and 90.6% for AMACR
#10659
middle Confidence
Subject:
AMACR
(Enzymes)
→
is_expressed_at
→
Object:
foamy_gland_carcinoma
(Tumor type)
Original: Immunohistochemical markers in foamy gland carcinoma#are expressed at#90.1% for p63/ 90.6% for 34Beta12/ and 90.6% for AMACR
#10658
middle Confidence
Subject:
p63
(Transcription Factors)
→
is_expressed_at
→
Object:
foamy_gland_carcinoma
(Tumor type)
Original: Immunohistochemical markers in foamy gland carcinoma#are expressed at#90.1% for p63/ 90.6% for 34Beta12/ and 90.6% for AMACR
#10650
middle Confidence
Subject:
NORs_activity
(Molecular function)
→
helps_in
→
Object:
differential_diagnosis_of_in_situ_adenocarcinomas
(Diagnostic Process)
Original: NORs activity#helps in#differential diagnosis of adenomas and in situ adenocarcinomas
#10649
middle Confidence
Subject:
NORs_activity
(Molecular function)
→
helps_in
→
Object:
differential_diagnosis_of_adenomas
(Diagnostic Process)
Original: NORs activity#helps in#differential diagnosis of adenomas and in situ adenocarcinomas
#10645
middle Confidence
Subject:
MIB1
(Proliferation Nuclear Antigen)
→
is_downregulated_in
→
Object:
proliferative_activity
(Cellular Processes)
Original: sections stained for mib-1#expressed#very low proliferative activity
#10568
middle Confidence
Subject:
urothelial_carcinoma
(Tumor type)
→
shows
→
Object:
invasive_carcinoma
(Tumor phenotype)
Original: urothelial carcinoma#showed#both DCIS and invasive carcinoma in 6 of 21 cases
#10567
middle Confidence
Subject:
urothelial_carcinoma
(Tumor type)
→
shows
→
Object:
DCIS
(Tumor phenotype)
Original: urothelial carcinoma#showed#both DCIS and invasive carcinoma in 6 of 21 cases
#10540
middle Confidence
Subject:
Epithelial_cells
(Epithelial cells)
→
display
→
Object:
diagnostic_cytologic_features
(Cell morphology)
Original: Low grade papillary adenocarcinomas of minor salivary gland origin (LPA)#are described as#diagnostic cytologic features
#10485
middle Confidence
Subject:
Diagnosis
(Clinical course)
→
was_of
→
Object:
Leukemia
(Disease phenotype)
Original: Diagnosis#was of#NHML in 6 cases and secondary involvement of hematopoietic malignancy in 2 cases
#10484
middle Confidence
Subject:
Diagnosis
(Clinical course)
→
was_of
→
Object:
myeloid_sarcoma
(Disease phenotype)
Original: Diagnosis#was of#NHML in 6 cases and secondary involvement of hematopoietic malignancy in 2 cases
#10483
middle Confidence
Subject:
Diagnosis
(Clinical course)
→
was_of
→
Object:
NHML
(Disease phenotype)
Original: Diagnosis#was of#NHML in 6 cases and secondary involvement of hematopoietic malignancy in 2 cases
#10482
middle Confidence
Subject:
Histologic_examination
(Technical Process)
→
revealed
→
Object:
grade_2_conventional_chondrosarcoma
(Disease phenotype)
Original: Histologic examination#revealed#grade 2 conventional chondrosarcomas with multiple foci resembling clear cell chondrosarcoma
#10479
middle Confidence
Subject:
cytologic_analysis
(Cytology)
→
detected
→
Object:
eosinophilic_nucleoli
(Nuclear structure)
Original: cytologic analysis#detected#tumor cells with increased euchromatin and stretched nuclear membranes
#10478
middle Confidence
Subject:
cytologic_analysis
(Cytology)
→
detected
→
Object:
stretched_nuclear_membranes
(Nuclear structure)
Original: cytologic analysis#detected#tumor cells with increased euchromatin and stretched nuclear membranes
#10477
middle Confidence
Subject:
cytologic_analysis
(Cytology)
→
detected
→
Object:
increased_euchromatin
(Nuclear structure)
Original: cytologic analysis#detected#tumor cells with increased euchromatin and stretched nuclear membranes
#10476
middle Confidence
Subject:
Transvaginal_ultrasound
(Ultrasonography)
→
shows
→
Object:
multiple_cervical_cysts
(Tissue abnormalities)
Original: Transvaginal ultrasound#showed#multiple cervical cysts
#10475
middle Confidence
Subject:
adenoma_malignum
(Tumor type)
→
was_diagnosed_by
→
Object:
Cytology
(Cytology)
Original: a case of adenoma malignum#was diagnosed#cytologically
#10474
middle Confidence
Subject:
3D_reconstruction
(3D reconstruction technology)
→
is_used_for
→
Object:
adenoma_malignum
(Tumor type)
Original: adenoma malignum#is studied using#cytology/ immunohistochemistry/ and 3D reconstruction
#10473
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
is_used_for
→
Object:
adenoma_malignum
(Tumor type)
Original: adenoma malignum#is studied using#cytology/ immunohistochemistry/ and 3D reconstruction
#10472
middle Confidence
Subject:
Cytology
(Cytology)
→
is_used_for
→
Object:
adenoma_malignum
(Tumor type)
Original: adenoma malignum#is studied using#cytology/ immunohistochemistry/ and 3D reconstruction
#10451
middle Confidence
Subject:
FNAC_findings
(Fine needle aspiration cytology)
→
described
→
Object:
spermatocytic_seminoma
(Tumor)
Original: FNAC findings#described#a case of spermatocytic seminoma in a 52-year-old male
#10450
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
broaden the spectrum of
→
Object:
lymphoid_malignancies
(Tumor)
Original: Cytologic findings#broaden the spectrum of#lymphoid malignancies
#10447
middle Confidence
Subject:
poorly_differentiated_SCC
(Tumor diseases)
→
overlaps_with
→
Object:
urothelial_carcinoma
(Tumor diseases)
Original: poorly differentiated SCC#overlaps with#reactive mesothelial cells/ mesothelioma/ metastatic adenocarcinoma/ urothelial carcinoma
#10446
middle Confidence
Subject:
poorly_differentiated_SCC
(Tumor diseases)
→
overlaps_with
→
Object:
metastatic_adenocarcinoma
(Tumor diseases)
Original: poorly differentiated SCC#overlaps with#reactive mesothelial cells/ mesothelioma/ metastatic adenocarcinoma/ urothelial carcinoma
#10445
middle Confidence
Subject:
poorly_differentiated_SCC
(Tumor diseases)
→
overlaps_with
→
Object:
mesothelioma
(Tumor diseases)
Original: poorly differentiated SCC#overlaps with#reactive mesothelial cells/ mesothelioma/ metastatic adenocarcinoma/ urothelial carcinoma
#10444
middle Confidence
Subject:
poorly_differentiated_SCC
(Tumor diseases)
→
overlaps_with
→
Object:
reactive_mesothelial_cells
(Cell Type)
Original: poorly differentiated SCC#overlaps with#reactive mesothelial cells/ mesothelioma/ metastatic adenocarcinoma/ urothelial carcinoma
#10422
middle Confidence
Subject:
malignant_neoplastic_cells
(Tumor cells)
→
identified_in
→
Object:
specimens
(sample)
Original: Malignant neoplastic cells#were identified in#57% of specimens from 60% of patients
#10361
middle Confidence
Subject:
signet_ring_cell
(Cell Type)
→
present_in
→
Object:
pulmonary_adenocarcinoma
(Lung adenocarcinoma)
Original: 11 cases#showed#presence of signet ring cells out of 218 pulmonary adenocarcinomas
#10359
middle Confidence
Subject:
malignant_cell
(Cell Type)
→
were_observed_in
→
Object:
patient_with_breast_carcinoma
(patient)
Original: Malignant cells#were observed in#2 of 38 patients with breast carcinoma
#10351
middle Confidence
Subject:
Small_cell_morphology
(Cell morphology)
→
is_associated_with
→
Object:
neoplastic_cells_on_exfoliative_respiratory_cytology
(Tumor cells)
Original: Small cell morphology#is associated with#neoplastic cells on exfoliative respiratory cytology
#10346
middle Confidence
Subject:
adenoma
(Neoplastic lesions)
→
shows
→
Object:
high-grade_dysplasia
(Pathological characteristics)
Original: 4 adenomas#showed#high-grade dysplasia
#10345
middle Confidence
Subject:
cytologic_diagnosis
(Diagnosis)
→
was_correlated_with
→
Object:
histology_report
(Pathology report)
Original: cytologic diagnoses#were correlated with#histology report on 100 cases
#10343
middle Confidence
Subject:
Merkel_cell_carcinoma
(Tumor Entities)
→
is_distinguished_by
→
Object:
immunophenotypical_features
(Immunophenotypic characteristics)
Original: Merkel cell carcinoma#is distinguished by#morphologic and immunophenotypical features
#10342
middle Confidence
Subject:
Merkel_cell_carcinoma
(Tumor Entities)
→
is_distinguished_by
→
Object:
morphologic_features
(Morphological characteristics)
Original: Merkel cell carcinoma#is distinguished by#morphologic and immunophenotypical features
#10327
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
expresses
→
Object:
lambda_chains
(Immunoglobulin light chain)
Original: tumor cells#express#CD45/ CD20/ HLA-DR/ and monoclonal IgM-lambda and lambda chains
#10326
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
expresses
→
Object:
monoclonal_IgM-lambda
(Monoclonal immunoglobulin)
Original: tumor cells#express#CD45/ CD20/ HLA-DR/ and monoclonal IgM-lambda and lambda chains
#10325
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
expresses
→
Object:
HLA-DR
(major histocompatibility complex protein)
Original: tumor cells#express#CD45/ CD20/ HLA-DR/ and monoclonal IgM-lambda and lambda chains
#10324
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
expresses
→
Object:
CD20
(Cell membrane proteins)
Original: tumor cells#express#CD45/ CD20/ HLA-DR/ and monoclonal IgM-lambda and lambda chains
#10323
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
expresses
→
Object:
CD45
(Cell membrane proteins)
Original: tumor cells#express#CD45/ CD20/ HLA-DR/ and monoclonal IgM-lambda and lambda chains
#10319
middle Confidence
Subject:
CT
(Computed tomography)
→
showed
→
Object:
bone_destruction
(Imaging findings)
Original: CT#showed#osteolytic lesion with bone destruction in mandible
#10318
middle Confidence
Subject:
CT
(Computed tomography)
→
showed
→
Object:
osteolytic_lesion_in_mandible
(Imaging findings)
Original: CT#showed#osteolytic lesion with bone destruction in mandible
#10314
middle Confidence
Subject:
atypical_cells
(Abnormal cells)
→
characterized_by
→
Object:
multiple_nucleoli
(Nuclear structure)
Original: Cerebrospinal fluid analysis#found#atypical cells with hyperchromatic nuclei and multiple nucleoli
#10313
middle Confidence
Subject:
atypical_cells
(Abnormal cells)
→
characterized_by
→
Object:
hyperchromatic_nuclei
(Nuclear morphology)
Original: Cerebrospinal fluid analysis#found#atypical cells with hyperchromatic nuclei and multiple nucleoli
#10312
middle Confidence
Subject:
cerebrospinal_fluid_analysis
(Cerebrospinal fluid analysis)
→
found
→
Object:
atypical_cells
(Cell Type)
Original: Cerebrospinal fluid analysis#found#atypical cells with hyperchromatic nuclei and multiple nucleoli
#10311
middle Confidence
Subject:
MRI
(Magnetic resonance imaging)
→
showed
→
Object:
meninges_involvement
(Imaging findings)
Original: MRI#showed#a progressively enlarged nodule in the prepontine cistern with meninges involvement
#10310
middle Confidence
Subject:
MRI
(Magnetic resonance imaging)
→
showed
→
Object:
progressively_enlarged_nodule_in_prepontine_cistern
(Imaging findings)
Original: MRI#showed#a progressively enlarged nodule in the prepontine cistern with meninges involvement
#10309
middle Confidence
Subject:
autopsy
(Autopsy)
→
revealed
→
Object:
no_metastatic_lesions_in_lymph_nodes
(Disease phenotype)
Original: Autopsy#revealed#no metastatic lesions in organs or lymph nodes
#10308
middle Confidence
Subject:
autopsy
(Autopsy)
→
revealed
→
Object:
no_metastatic_lesions_in_organs
(Disease phenotype)
Original: Autopsy#revealed#no metastatic lesions in organs or lymph nodes
#10296
middle Confidence
Subject:
large_cells
(Tumor cells)
→
shows
→
Object:
prominent_nucleoli
(Nucleolus)
Original: apocrine carcinomas#are characterized by#large cells with eosinophilic granular cytoplasm/ round nuclei/ and prominent nucleoli
#10295
middle Confidence
Subject:
large_cells
(Tumor cells)
→
shows
→
Object:
round_nuclei
(Nuclear morphology)
Original: apocrine carcinomas#are characterized by#large cells with eosinophilic granular cytoplasm/ round nuclei/ and prominent nucleoli
#10294
middle Confidence
Subject:
large_cells
(Tumor cells)
→
shows
→
Object:
eosinophilic_granular_cytoplasm
(Cytoplasmic characteristics)
Original: apocrine carcinomas#are characterized by#large cells with eosinophilic granular cytoplasm/ round nuclei/ and prominent nucleoli
#10293
middle Confidence
Subject:
epithelioid_cells
(Epithelioid cells)
→
shows
→
Object:
prominent_nucleoli
(Nucleolus)
Original: lesion#consists of#epithelioid cells with high-grade nuclei and prominent nucleoli
#10292
middle Confidence
Subject:
epithelioid_cells
(Epithelioid cells)
→
shows
→
Object:
high-grade_nuclei
(Nuclear fractionation)
Original: lesion#consists of#epithelioid cells with high-grade nuclei and prominent nucleoli
#10291
middle Confidence
Subject:
lesion
(Diseased tissue)
→
consists_of
→
Object:
epithelioid_cells
(Cell Type)
Original: lesion#consists of#epithelioid cells with high-grade nuclei and prominent nucleoli
#10284
middle Confidence
Subject:
neoplasm
(Tumor)
→
is_composed_of
→
Object:
polygonal_cells_with_prominent_nucleoli
(Cell morphology)
Original: neoplasm#was composed of#polygonal cells with prominent nucleoli
#10267
middle Confidence
Subject:
primary_pancreatic_lymphomas
(Tumor Entities)
→
includes
→
Object:
diarrhea
(Clinical symptoms)
Original: Common clinical manifestations#include#abdominal pain/ jaundice/ acute pancreatitis/ small bowel obstruction/ and diarrhea
#10266
middle Confidence
Subject:
primary_pancreatic_lymphomas
(Tumor Entities)
→
includes
→
Object:
small_bowel_obstruction
(Clinical symptoms)
Original: Common clinical manifestations#include#abdominal pain/ jaundice/ acute pancreatitis/ small bowel obstruction/ and diarrhea
#10265
middle Confidence
Subject:
primary_pancreatic_lymphomas
(Tumor Entities)
→
includes
→
Object:
acute_pancreatitis
(Clinical symptoms)
Original: Common clinical manifestations#include#abdominal pain/ jaundice/ acute pancreatitis/ small bowel obstruction/ and diarrhea
#10264
middle Confidence
Subject:
primary_pancreatic_lymphomas
(Tumor Entities)
→
includes
→
Object:
jaundice
(Clinical symptoms)
Original: Common clinical manifestations#include#abdominal pain/ jaundice/ acute pancreatitis/ small bowel obstruction/ and diarrhea
#10263
middle Confidence
Subject:
primary_pancreatic_lymphomas
(Tumor Entities)
→
includes
→
Object:
abdominal_pain
(Clinical symptoms)
Original: Common clinical manifestations#include#abdominal pain/ jaundice/ acute pancreatitis/ small bowel obstruction/ and diarrhea
#10262
middle Confidence
Subject:
primary_pancreatic_lymphomas
(Tumor Entities)
→
present_with
→
Object:
symptoms_of_pancreatic_head_carcinoma
(Clinical symptoms)
Original: Primary pancreatic lymphomas#present with#symptoms of carcinoma of the pancreatic head
#10261
middle Confidence
Subject:
vulvar_cutaneous_myxomas
(Tumor Entities)
→
pose
→
Object:
diagnostic_challenge
(Difficulties in diagnosis)
Original: Vulvar cutaneous myxomas#pose#a significant diagnostic challenge
#10256
middle Confidence
Subject:
Amelanotic_melanoma
(Tumor type)
→
shares_morphology_with
→
Object:
non-epithelial_malignant_tumors
(Tumor type)
Original: Amelanotic melanoma#has#similar morphology to a wide variety of epithelial and non-epithelial malignant tumors
#10255
middle Confidence
Subject:
Amelanotic_melanoma
(Tumor type)
→
shares_morphology_with
→
Object:
epithelial_malignant_tumors
(Tumor type)
Original: Amelanotic melanoma#has#similar morphology to a wide variety of epithelial and non-epithelial malignant tumors
#10246
middle Confidence
Subject:
metastases
(Disease phenotype)
→
were_detected_in
→
Object:
Sorry, I have no idea what this means.
(organ)
Original: multiple metastases#were detected in#the spleen
#10243
middle Confidence
Subject:
metastatic_carcinoma
(Malignant tumors)
→
was_diagnosed
→
Object:
urothelial_origin
(Organ Source)
Original: A metastatic carcinoma#was diagnosed#with presumed prostatic or urothelial origin
#10242
middle Confidence
Subject:
metastatic_carcinoma
(Malignant tumors)
→
was_diagnosed
→
Object:
prostatic_origin
(Organ Source)
Original: A metastatic carcinoma#was diagnosed#with presumed prostatic or urothelial origin
#10241
middle Confidence
Subject:
epithelioid_angiosarcoma
(Tumor tissue)
→
is_characterized_by
→
Object:
prominent_nucleoli
(Nuclear components)
Original: epithelioid angiosarcomas#are characterized by#neoplastic cellular proliferation with round to oval nuclei and prominent nucleoli
#10240
middle Confidence
Subject:
epithelioid_angiosarcoma
(Tumor tissue)
→
is_characterized_by
→
Object:
round_to_oval_nuclei
(Nuclear components)
Original: epithelioid angiosarcomas#are characterized by#neoplastic cellular proliferation with round to oval nuclei and prominent nucleoli
#10215
middle Confidence
Subject:
histiocytes
(Cell Type)
→
present_in
→
Object:
nodular_lesions
(Organizational Structure)
Original: Nodular lesions#contain#lymphocytic cells and histiocytes
#10214
middle Confidence
Subject:
lymphocytic_cells
(Cell Type)
→
present_in
→
Object:
nodular_lesions
(Organizational Structure)
Original: Nodular lesions#contain#lymphocytic cells and histiocytes
#10212
middle Confidence
Subject:
bland_cells_with_pale_granular_cytoplasm_and_inconspicuous_nucleoli
(Cell morphology)
→
observed_in
→
Object:
aspirate_smears
(Cytology specimens)
Original: Aspirate smears#showed#bland cells with pale granular cytoplasm and inconspicuous nucleoli
#10146
middle Confidence
Subject:
primary_malignant_melanoma
(Malignant melanoma)
→
arose_in
→
Object:
ovarian_dermoid_cyst
(Ovarian teratoma)
Original: Primary malignant melanoma#arose in#an ovarian dermoid cyst
#10117
middle Confidence
Subject:
AgNOR
(Nucleolar silver staining marker)
→
was_labeled_in
→
Object:
serial_sections
(Tissue sections)
Original: serial sections#were labeled for#Ki-67 (MIB1) and argyrophilic nucleolar organizer regions (AgNORs)
#10116
middle Confidence
Subject:
Ki-67
(Cell proliferation markers)
→
was_labeled_in
→
Object:
serial_sections
(Tissue sections)
Original: serial sections#were labeled for#Ki-67 (MIB1) and argyrophilic nucleolar organizer regions (AgNORs)
#10115
middle Confidence
Subject:
estrogen_receptor_detection_technique
(Molecular detection technology)
→
is_applied_to
→
Object:
endometrial_cystic_hyperplasia
(Benign lesions)
Original: AgNOR staining technique and estrogen receptor (ER) detective technique#are applied to#endometrial adenocarcinoma and endometrial cystic hyperplasia
#10114
middle Confidence
Subject:
estrogen_receptor_detection_technique
(Molecular detection technology)
→
is_applied_to
→
Object:
endometrial_adenocarcinoma
(Tumor type)
Original: AgNOR staining technique and estrogen receptor (ER) detective technique#are applied to#endometrial adenocarcinoma and endometrial cystic hyperplasia
#10113
middle Confidence
Subject:
AgNOR_staining_technique
(Dyeing technology)
→
is_applied_to
→
Object:
endometrial_cystic_hyperplasia
(Benign lesions)
Original: AgNOR staining technique and estrogen receptor (ER) detective technique#are applied to#endometrial adenocarcinoma and endometrial cystic hyperplasia
#10112
middle Confidence
Subject:
AgNOR_staining_technique
(Dyeing technology)
→
is_applied_to
→
Object:
endometrial_adenocarcinoma
(Tumor type)
Original: AgNOR staining technique and estrogen receptor (ER) detective technique#are applied to#endometrial adenocarcinoma and endometrial cystic hyperplasia
#10073
middle Confidence
Subject:
Tumor cells
(Tumor cells)
→
were_positive_for
→
Object:
chromogranin A
(protein)
Original: Tumor cells#were positive for#cytokeratin 20 (CK20)/ neuron-specific enolase/ pancytokeratin/ epithelial membrane antigen/ chromogranin A expression
#10072
middle Confidence
Subject:
Tumor cells
(Tumor cells)
→
were_positive_for
→
Object:
epithelial membrane antigen
(protein)
Original: Tumor cells#were positive for#cytokeratin 20 (CK20)/ neuron-specific enolase/ pancytokeratin/ epithelial membrane antigen/ chromogranin A expression
#10071
middle Confidence
Subject:
Tumor cells
(Tumor cells)
→
were_positive_for
→
Object:
pancytokeratin
(protein)
Original: Tumor cells#were positive for#cytokeratin 20 (CK20)/ neuron-specific enolase/ pancytokeratin/ epithelial membrane antigen/ chromogranin A expression
#10070
middle Confidence
Subject:
Tumor cells
(Tumor cells)
→
were_positive_for
→
Object:
neuron-specific enolase
(protein)
Original: Tumor cells#were positive for#cytokeratin 20 (CK20)/ neuron-specific enolase/ pancytokeratin/ epithelial membrane antigen/ chromogranin A expression
#10069
middle Confidence
Subject:
Tumor cells
(Tumor cells)
→
were_positive_for
→
Object:
Cytokeratin 20 (CK20)
(protein)
Original: Tumor cells#were positive for#cytokeratin 20 (CK20)/ neuron-specific enolase/ pancytokeratin/ epithelial membrane antigen/ chromogranin A expression
#10068
middle Confidence
Subject:
Xenotransplanted tumor
(Transplanted tumor tissue)
→
showed
→
Object:
positive immunoreactivity for chromogranin A
(protein)
Original: Xenotransplanted tumor#showed#positive immunoreactivity for calcitonin/ CGRP/ and chromogranin A
#10067
middle Confidence
Subject:
Xenotransplanted tumor
(Transplanted tumor tissue)
→
showed
→
Object:
positive immunoreactivity for CGRP
(protein)
Original: Xenotransplanted tumor#showed#positive immunoreactivity for calcitonin/ CGRP/ and chromogranin A
#10066
middle Confidence
Subject:
Xenotransplanted tumor
(Transplanted tumor tissue)
→
showed
→
Object:
positive immunoreactivity for calcitonin
(protein)
Original: Xenotransplanted tumor#showed#positive immunoreactivity for calcitonin/ CGRP/ and chromogranin A
#10062
middle Confidence
Subject:
white_cell_count
(Clinical indicators)
→
is
→
Object:
26.2x10^9/L_with_95%_abnormal_lymphoid_cells
(Clinical measurements)
Original: White cell count#was#26.2x10(9)/L with 95% abnormal lymphoid cells
#9957
middle Confidence
Subject:
Primary_carcinomas_of_ileum
(Tumor)
→
are_identified_with
→
Object:
sarcomatoid_histology
(Tumor morphological characteristics)
Original: Primary carcinomas of jejunum or ileum#are identified with#anaplastic and sarcomatoid histology
#9956
middle Confidence
Subject:
Primary_carcinomas_of_jejunum
(Tumor)
→
are_identified_with
→
Object:
anaplastic_histology
(Tumor morphological characteristics)
Original: Primary carcinomas of jejunum or ileum#are identified with#anaplastic and sarcomatoid histology
#9955
middle Confidence
Subject:
Adenocarcinoma_of_the_apocrine_gland
(Glandular adenocarcinoma)
→
is_included_in
→
Object:
cytologic_differential_diagnosis_of_anal_sac_masses_in_dogs
(Diagnostic Process)
Original: Adenocarcinoma of the apocrine gland#is included in#cytologic differential diagnosis of anal sac masses in dogs
#9888
middle Confidence
Subject:
AgNOR_technique
(Dyeing technology)
→
evaluates
→
Object:
Nucleolar_organizer_regions_in_breast_lumps
(Molecular markers)
Original: AgNOR technique#evaluates#nucleolar organizer regions in breast lumps
#9887
middle Confidence
Subject:
Sequential_cytologic_examinations
(Cytology)
→
detect
→
Object:
Individual_cell_changes
(Cell phenotype changes)
Original: Sequential cytologic examinations#detect#individual cell changes
#9886
middle Confidence
Subject:
Smears
(Cytosmear)
→
is_studied_in
→
Object:
Malignant_cases
(Malignant cases)
Original: Correlation between smears and sections#is studied in#benign and malignant cases
#9885
middle Confidence
Subject:
Smears
(Cytosmear)
→
is_studied_in
→
Object:
Benign_cases
(Benign cases)
Original: Correlation between smears and sections#is studied in#benign and malignant cases
#9884
middle Confidence
Subject:
Silver_staining_method
(Dyeing technology)
→
is_used_to_determine
→
Object:
AgNORs_per_cell
(Molecular markers)
Original: Silver staining method#is used to determine#AgNORs per cell
#9874
middle Confidence
Subject:
AgNOR_protein_quantity
(Protein expression)
→
was_determined_in
→
Object:
colposcopic-directed_biopsies_of_CIN_lesions
(Histological samples)
Original: AgNOR protein quantity#was determined in#colposcopic-directed biopsies of CIN lesions
#9873
middle Confidence
Subject:
AgNOR_protein_distribution
(Protein distribution characteristics)
→
was_determined_in
→
Object:
cervical_smears_from_CIN_grades_I-III
(Cytology samples)
Original: AgNOR protein distribution#was determined in#cervical smears from normal cervix and CIN grades I-III
#9872
middle Confidence
Subject:
AgNOR_protein_distribution
(Protein distribution characteristics)
→
was_determined_in
→
Object:
cervical_smears_from_normal_cervix
(Cytology samples)
Original: AgNOR protein distribution#was determined in#cervical smears from normal cervix and CIN grades I-III
#9862
middle Confidence
Subject:
small_cell_type
(Small cell type)
→
is_important_for
→
Object:
differential_diagnosis
(Differential Diagnosis)
Original: small cell types of the tumor#are important for#differential diagnosis
#9861
middle Confidence
Subject:
Non_Hodgkins_lymphoma
(Non-Hodgkin's lymphoma)
→
are_evaluated_with
→
Object:
mitotic_regimen
(Mitosis scheme)
Original: NHL of low and high grades#are evaluated with#Ag-NOR and mitotic regimen
#9855
middle Confidence
Subject:
Ag-NOR_expression
(Nucleolar organizer region expression)
→
is_tested_on
→
Object:
carcinoma_ex_PA
(Malignant tumors)
Original: Ag-NOR expression#is tested on#cases of recurrent and non-recurrent PA and carcinoma ex PA
#9854
middle Confidence
Subject:
Ag-NOR_expression
(Nucleolar organizer region expression)
→
is_tested_on
→
Object:
non_recurrent_PA
(Tumor)
Original: Ag-NOR expression#is tested on#cases of recurrent and non-recurrent PA and carcinoma ex PA
#9853
middle Confidence
Subject:
Ag-NOR_expression
(Nucleolar organizer region expression)
→
is_tested_on
→
Object:
recurrent_PA
(Tumor recurrence)
Original: Ag-NOR expression#is tested on#cases of recurrent and non-recurrent PA and carcinoma ex PA
#9774
middle Confidence
Subject:
AgNOR_counts
(Molecular markers)
→
was_performed_on
→
Object:
exfoliative_cytology_specimens
(Cytology samples)
Original: Quantitative analysis of AgNOR counts#was performed on#exfoliative cytology specimens of oral mucosa
#9771
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
were_studied_in
→
Object:
melanocytic_skin_tumors
(Tumor)
Original: Silver staining AgNORs#were studied in#melanocytic skin tumors
#9757
middle Confidence
Subject:
silver_stainable_NORs
(Silver-stainable nucleolar organizer region)
→
may_help_characterize
→
Object:
dysplasia
(Abnormal growth)
Original: Silver stainable nucleolar organizer regions#may have a place in#characterizing dysplasia in tissue specimens
#9754
middle Confidence
Subject:
PCNA
(protein)
→
detected_in
→
Object:
colorectal_adenomas_with_invasive_carcinoma
(Invasive colorectal adenoma)
Original: AgNOR staining/ Ki67/ DNA polymerase alpha/ and PCNA detection#were carried out on#colorectal adenomas containing invasive carcinoma
#9753
middle Confidence
Subject:
POLA1
(DNA polymerase)
→
detected_in
→
Object:
colorectal_adenomas_with_invasive_carcinoma
(Invasive colorectal adenoma)
Original: AgNOR staining/ Ki67/ DNA polymerase alpha/ and PCNA detection#were carried out on#colorectal adenomas containing invasive carcinoma
#9752
middle Confidence
Subject:
KI67
(protein)
→
detected_in
→
Object:
colorectal_adenomas_with_invasive_carcinoma
(Invasive colorectal adenoma)
Original: AgNOR staining/ Ki67/ DNA polymerase alpha/ and PCNA detection#were carried out on#colorectal adenomas containing invasive carcinoma
#9751
middle Confidence
Subject:
AgNOR_staining
(Dyeing technology)
→
carried_out_on
→
Object:
colorectal_adenomas_with_invasive_carcinoma
(Invasive colorectal adenoma)
Original: AgNOR staining/ Ki67/ DNA polymerase alpha/ and PCNA detection#were carried out on#colorectal adenomas containing invasive carcinoma
#9750
middle Confidence
Subject:
AgNOR_staining_technique
(Dyeing technology)
→
used_in
→
Object:
giant_cell_lesions_of_the_jaws
(Giant cell jaw disease)
Original: Giant cell lesions of the jaws#were studied using#AgNOR staining technique
#9741
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
measured_in
→
Object:
Hashimoto_thyroiditis
(Hashimoto's thyroiditis)
Original: AgNOR counts#were evaluated in#smears of 70 thyroid lesions
#9740
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
measured_in
→
Object:
nodular_goiter
(Nodular goiter)
Original: AgNOR counts#were evaluated in#smears of 70 thyroid lesions
#9739
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
measured_in
→
Object:
papillary_carcinoma
(Papillary carcinoma)
Original: AgNOR counts#were evaluated in#smears of 70 thyroid lesions
#9738
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
measured_in
→
Object:
follicular_carcinoma
(Follicular carcinoma)
Original: AgNOR counts#were evaluated in#smears of 70 thyroid lesions
#9737
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
measured_in
→
Object:
follicular_adenoma
(Follicular adenoma)
Original: AgNOR counts#were evaluated in#smears of 70 thyroid lesions
#9736
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region count)
→
measured_in
→
Object:
thyroid_lesion_smears
(Thyroid lesion smear)
Original: AgNOR counts#were evaluated in#smears of 70 thyroid lesions
#9735
middle Confidence
Subject:
ITGCN
(Germ cell tumor in situ)
→
is_present_adjacent_to
→
Object:
invasive_germ_cell_tumor
(Aggressive germ cell tumor)
Original: ITGCN#is present#adjacent to most invasive germ cell tumors
#9719
middle Confidence
Subject:
Proliferative_activity
(Cell proliferation activity)
→
was_measured_using
→
Object:
AgNOR
(Nucleolar organizer region-associated protein)
Original: Proliferative activity#was measured using#silver-stained nucleolar organizing regions (AgNOR) in biopsies of AAH/ PIN/ and carcinomas
#9718
middle Confidence
Subject:
Proliferative_activity
(Cell proliferation activity)
→
was_measured_using
→
Object:
AgNOR
(Nucleolar organizer region-associated protein)
Original: Proliferative activity#was measured using#silver-stained nucleolar organizing regions (AgNOR) in biopsies of AAH/ PIN/ and carcinomas
#9717
middle Confidence
Subject:
Proliferative_activity
(Cell proliferation activity)
→
was_measured_using
→
Object:
AgNOR
(Nucleolar organizer region-associated protein)
Original: Proliferative activity#was measured using#silver-stained nucleolar organizing regions (AgNOR) in biopsies of AAH/ PIN/ and carcinomas
#9715
middle Confidence
Subject:
Proliferation_indices
(Cell proliferation index)
→
were_determined_using
→
Object:
AgNOR_stain
(Dyeing technology)
Original: Proliferation indices#were determined for#liver metastatic tumors using AgNOR stain
#9714
middle Confidence
Subject:
Proliferation_indices
(Cell proliferation index)
→
were_determined_using
→
Object:
AgNOR_stain
(Dyeing technology)
Original: Proliferation indices#were determined for#liver metastatic tumors using AgNOR stain
#9711
middle Confidence
Subject:
borderline_tumors
(Tumor type)
→
showed
→
Object:
DNA_diploidy
(Genome ploidy)
Original: borderline tumors#showed#elevated AgNOR numbers despite low proliferative indices and DNA diploidy
#9710
middle Confidence
Subject:
borderline_tumors
(Tumor type)
→
showed
→
Object:
low_proliferative_indices
(Cell proliferation index)
Original: borderline tumors#showed#elevated AgNOR numbers despite low proliferative indices and DNA diploidy
#9709
middle Confidence
Subject:
borderline_tumors
(Tumor type)
→
showed
→
Object:
elevated_AgNOR_numbers
(Cell proliferation markers)
Original: borderline tumors#showed#elevated AgNOR numbers despite low proliferative indices and DNA diploidy
#9702
middle Confidence
Subject:
Neuroendocrine tumors
(Tumor type)
→
showed
→
Object:
cells_arranged_in_cords_or_nests
(Histological structure)
Original: Neuroendocrine tumors#showed#cells arranged in cords or nests with Ki-67 index of 5% (G2 neuroendocrine tumor) and 80% (small-cell neuroendocrine carcinoma)
#9697
middle Confidence
Subject:
AgNOR_silver_staining
(Molecular markers)
→
is_studied_in
→
Object:
malignant_gastric_stromal_tumors
(Tumor type)
Original: Silver staining of AgNOR#was studied in#primary benign and malignant gastric stromal tumors
#9696
middle Confidence
Subject:
AgNOR_silver_staining
(Molecular markers)
→
is_studied_in
→
Object:
benign_gastric_stromal_tumors
(Tumor type)
Original: Silver staining of AgNOR#was studied in#primary benign and malignant gastric stromal tumors
#9694
middle Confidence
Subject:
AgNOR_numbers
(Molecular markers)
→
is_compared_in
→
Object:
colorectal_cancer
(Tumor type)
Original: Immunoreactive p53 and AgNOR numbers#were compared in#colorectal cancers with and without hepatic metastasis
#9692
middle Confidence
Subject:
immunoreactive_p53
(protein)
→
is_compared_in
→
Object:
colorectal_cancer
(Tumor type)
Original: Immunoreactive p53 and AgNOR numbers#were compared in#colorectal cancers with and without hepatic metastasis
#9682
middle Confidence
Subject:
NPM_expression
(Protein expression)
→
was_investigated_in
→
Object:
renal_oncocytomas
(Tumor type)
Original: NPM expression#was investigated#in RCCs and renal oncocytomas
#9681
middle Confidence
Subject:
NPM_expression
(Protein expression)
→
was_investigated_in
→
Object:
renal_cell_carcinoma
(Tumor type)
Original: NPM expression#was investigated#in RCCs and renal oncocytomas
#9679
middle Confidence
Subject:
PCNA_expression
(Protein expression)
→
is_compared_with
→
Object:
AgNOR_numbers
(Molecular markers)
Original: PCNA expression#is compared with#tumor grade/ mitotic index/ and AgNOR numbers
#9678
middle Confidence
Subject:
PCNA_expression
(Protein expression)
→
is_compared_with
→
Object:
mitotic_index
(Cell division index)
Original: PCNA expression#is compared with#tumor grade/ mitotic index/ and AgNOR numbers
#9677
middle Confidence
Subject:
PCNA_expression
(Protein expression)
→
is_compared_with
→
Object:
tumor_grade
(Pathological grading)
Original: PCNA expression#is compared with#tumor grade/ mitotic index/ and AgNOR numbers
#9675
middle Confidence
Subject:
Cytological_anomaly
(Abnormal cell morphology)
→
is_observed_in
→
Object:
periphery_of_tubules
(Organizational Structure Area)
Original: Cytological anomaly#is observed in#periphery of the tubules
#9674
middle Confidence
Subject:
Histobiological_factors
(Histobiological characteristics)
→
are_assessed_at
→
Object:
invasive_tumor_front_of_OSCC
(Tumor tissue area)
Original: Histobiological factors#are assessed at#the invasive tumor front of oral squamous cell carcinomas
#9673
middle Confidence
Subject:
Cell_structures
(Cell structure)
→
are_correlated_with
→
Object:
histologic_types_of_lung_tumors
(Disease phenotype)
Original: Cell structures#are correlated with#histologic types of lung tumors
#9667
middle Confidence
Subject:
Nucleoli of cancer cells
(Nucleolus)
→
were_assessed_in
→
Object:
uveal_melanoma_tissue_specimens
(Tumor tissue specimens)
Original: Nucleoli of cancer cells#were assessed in#164 uveal melanoma tissue specimens
#9650
middle Confidence
Subject:
Prominent_nucleoli
(Cytological characteristics)
→
absent_in
→
Object:
SMILE_case
(Disease phenotype)
Original: Feathering and prominent nucleoli#were absent in#SMILE cases
#9649
middle Confidence
Subject:
Feathering
(Cytological characteristics)
→
absent_in
→
Object:
SMILE_case
(Disease phenotype)
Original: Feathering and prominent nucleoli#were absent in#SMILE cases
#9647
middle Confidence
Subject:
punch_biopsy
(Tissue biopsy)
→
suggested
→
Object:
lymphoepithelioma-like_carcinoma
(Tumor diseases)
Original: punch biopsy#suggested#a lymphoepithelioma-like carcinoma
#9637
middle Confidence
Subject:
Papillary_structures
(Pathological morphological entity)
→
were_observed
→
Object:
PcqI
(Disease classification)
Original: Papillary structures#were observed#more commonly in pUSC
#9635
middle Confidence
Subject:
Findings
(Pathological morphological entity)
→
included
→
Object:
supraspinatus_myonecrosis
(Disease phenotype)
Original: Findings#included#suppurative pancreatitis with peritonitis and supraspinatus myonecrosis
#9634
middle Confidence
Subject:
Findings
(Pathological morphological entity)
→
included
→
Object:
peritonitis
(Disease phenotype)
Original: Findings#included#suppurative pancreatitis with peritonitis and supraspinatus myonecrosis
#9633
middle Confidence
Subject:
Findings
(Pathological morphological entity)
→
included
→
Object:
suppurative_pancreatitis
(Disease phenotype)
Original: Findings#included#suppurative pancreatitis with peritonitis and supraspinatus myonecrosis
#9632
middle Confidence
Subject:
Autopsy_changes
(Pathological morphological entity)
→
consisted_of
→
Object:
yellow_fluid
(Pathological morphological entity)
Original: Autopsy changes#consisted of#hemorrhagic plaque/ chalky white nodules/ and yellow fluid
#9631
middle Confidence
Subject:
Autopsy_changes
(Pathological morphological entity)
→
consisted_of
→
Object:
chalky_white_nodules
(Pathological morphological entity)
Original: Autopsy changes#consisted of#hemorrhagic plaque/ chalky white nodules/ and yellow fluid
#9630
middle Confidence
Subject:
Autopsy_changes
(Pathological morphological entity)
→
consisted_of
→
Object:
hemorrhagic_plaque
(Pathological morphological entity)
Original: Autopsy changes#consisted of#hemorrhagic plaque/ chalky white nodules/ and yellow fluid
#9610
middle Confidence
Subject:
SS18 gene rearrangement
(Gene rearrangement)
→
is_detected_in
→
Object:
nuclei of tumor cells
(Tumor cell nucleus)
Original: SS18 gene rearrangement#is detected in#nuclei of tumor cells
#9609
middle Confidence
Subject:
DCIS
(Tumor diseases)
→
is
→
Object:
morphologically_diverse
(Disease phenotype)
Original: DCIS#is#morphologically diverse and cytologic features of individual cells on FNAB may distinguish C-DCIS from NC-DCIS
#9608
middle Confidence
Subject:
NC-DCIS
(Tumor diseases)
→
is
→
Object:
nonpalpable_lesion
(Disease phenotype)
Original: 60% of C-DCIS and 7 (88%) of NC-DCIS#were#nonpalpable lesions biopsied under conventional mammographic guidance
#9607
middle Confidence
Subject:
C-DCIS
(Tumor diseases)
→
is
→
Object:
nonpalpable_lesion
(Disease phenotype)
Original: 60% of C-DCIS and 7 (88%) of NC-DCIS#were#nonpalpable lesions biopsied under conventional mammographic guidance
#9583
middle Confidence
Subject:
Basophilic_and_prominent_nucleoli
(Nuclear morphology)
→
distinguish
→
Object:
lymphoplasmacytic_lymphoma
(Types of Lymphoma)
Original: Basophilic and prominent nucleoli#distinguish#immunoblastic lymphomas from lymphoplasmacytic lymphomas
#9582
middle Confidence
Subject:
Basophilic_and_prominent_nucleoli
(Nuclear morphology)
→
distinguish
→
Object:
immunoblastic_lymphoma
(Types of Lymphoma)
Original: Basophilic and prominent nucleoli#distinguish#immunoblastic lymphomas from lymphoplasmacytic lymphomas
#9572
middle Confidence
Subject:
clues_to_diagnosis
(Diagnostic clues)
→
include
→
Object:
mast_cells
(Cell Type)
Original: Clues to diagnosis#include#mature fat/ bland spindle cells/ myxoid background/ and mast cells
#9571
middle Confidence
Subject:
clues_to_diagnosis
(Diagnostic clues)
→
include
→
Object:
spindle_cells
(Cell Type)
Original: Clues to diagnosis#include#mature fat/ bland spindle cells/ myxoid background/ and mast cells
#9570
middle Confidence
Subject:
clues_to_diagnosis
(Diagnostic clues)
→
include
→
Object:
mature_fat
(Tissue composition)
Original: Clues to diagnosis#include#mature fat/ bland spindle cells/ myxoid background/ and mast cells
#9560
middle Confidence
Subject:
spontaneous_infarction_of_intraductal_papilloma
(Disease process)
→
is_considered_as
→
Object:
suspicious_for_malignancy
(Malignant tumor risk)
Original: Spontaneous infarction of intraductal papilloma#was considered as#suspicious for malignancy
#9559
middle Confidence
Subject:
spontaneous_infarction_of_intraductal_papilloma
(Disease process)
→
is_presented_as
→
Object:
cytological_presentation_on_fine_needle_aspiration
(Cytological manifestations)
Original: Spontaneous infarction of an intraductal papilloma of the breast#is presented as#a cytological presentation on fine needle aspiration
#9558
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological examination method)
→
showed
→
Object:
perivascular_pseudorosette_pattern
(Organizational Structure)
Original: Fine-needle aspiration biopsy#showed#enlarged uniform nuclei/ prominent nucleoli/ few mitotic figures/ karyolysis/ anuclear cells/ hyalinized nonepithelial cell clusters with hemosiderin deposits/ and a perivascular pseudorosette pattern
#9557
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological examination method)
→
showed
→
Object:
hyalinized_nonepithelial_cell_clusters_with_hemosiderin_deposits
(Cell clusters)
Original: Fine-needle aspiration biopsy#showed#enlarged uniform nuclei/ prominent nucleoli/ few mitotic figures/ karyolysis/ anuclear cells/ hyalinized nonepithelial cell clusters with hemosiderin deposits/ and a perivascular pseudorosette pattern
#9556
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological examination method)
→
showed
→
Object:
anuclear_cells
(Anucleated cells)
Original: Fine-needle aspiration biopsy#showed#enlarged uniform nuclei/ prominent nucleoli/ few mitotic figures/ karyolysis/ anuclear cells/ hyalinized nonepithelial cell clusters with hemosiderin deposits/ and a perivascular pseudorosette pattern
#9555
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological examination method)
→
showed
→
Object:
Karyolysis
(Nuclear lysis)
Original: Fine-needle aspiration biopsy#showed#enlarged uniform nuclei/ prominent nucleoli/ few mitotic figures/ karyolysis/ anuclear cells/ hyalinized nonepithelial cell clusters with hemosiderin deposits/ and a perivascular pseudorosette pattern
#9554
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological examination method)
→
showed
→
Object:
few_mitotic_figures
(Cell division)
Original: Fine-needle aspiration biopsy#showed#enlarged uniform nuclei/ prominent nucleoli/ few mitotic figures/ karyolysis/ anuclear cells/ hyalinized nonepithelial cell clusters with hemosiderin deposits/ and a perivascular pseudorosette pattern
#9553
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological examination method)
→
showed
→
Object:
prominent_nucleoli
(Nucleolus)
Original: Fine-needle aspiration biopsy#showed#enlarged uniform nuclei/ prominent nucleoli/ few mitotic figures/ karyolysis/ anuclear cells/ hyalinized nonepithelial cell clusters with hemosiderin deposits/ and a perivascular pseudorosette pattern
#9552
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological examination method)
→
showed
→
Object:
enlarged_uniform_nuclei
(Nucleus)
Original: Fine-needle aspiration biopsy#showed#enlarged uniform nuclei/ prominent nucleoli/ few mitotic figures/ karyolysis/ anuclear cells/ hyalinized nonepithelial cell clusters with hemosiderin deposits/ and a perivascular pseudorosette pattern
#9530
middle Confidence
Subject:
abdominal_mass
(Tumor)
→
is_detected_by
→
Object:
CT_scan
(Imaging Technology)
Original: CT scan#showed#swollen lymph nodes and a huge abdominal mass
#9529
middle Confidence
Subject:
undifferentiated_neoplasm
(Tumor tissue)
→
lacks
→
Object:
squamous_differentiation
(Histological characteristics)
Original: A biopsy#revealed#an undifferentiated neoplasm without squamous differentiation
#9511
middle Confidence
Subject:
Clinicopathologic_features_and_biomarker_expression
(Disease phenotype)
→
were_compared_between
→
Object:
ILC
(Tumor subtype)
Original: Clinicopathologic features and biomarker expression#were compared between#PLC and ILC
#9510
middle Confidence
Subject:
Clinicopathologic_features_and_biomarker_expression
(Disease phenotype)
→
were_compared_between
→
Object:
PLC
(Tumor subtype)
Original: Clinicopathologic features and biomarker expression#were compared between#PLC and ILC
#9455
middle Confidence
Subject:
tibial_biopsy
(Tissue specimens)
→
diagnosed_as
→
Object:
poorly_differentiated_adenocarcinoma
(Tumor type)
Original: Tibial biopsy#diagnosed as#poorly differentiated adenocarcinoma
#9442
middle Confidence
Subject:
TFCP2_rearrangement
(Genome rearrangement)
→
may_lead_to
→
Object:
misdiagnosis_as_other_spindle_cell_tumors
(Diagnostic Error)
Original: RMS with TFCP2 rearrangement#is#rare and may be misdiagnosed as other spindle cell tumors
#9441
middle Confidence
Subject:
TFCP2_rearrangement
(Genome rearrangement)
→
is_rare_in
→
Object:
RMS
(Tumor Entities)
Original: RMS with TFCP2 rearrangement#is#rare and may be misdiagnosed as other spindle cell tumors
#9440
middle Confidence
Subject:
cytospin_preparations
(Histological samples)
→
were_reviewed_with
→
Object:
biopsy_follow-up
(Diagnostic Process)
Original: Cytospin preparations from 331 cases#were reviewed with#biopsy follow-up
#9407
middle Confidence
Subject:
SCLC
(Tumor type)
→
is_characterized_by
→
Object:
rosette_like_structures
(Cell structure)
Original: SCLC#is characterized by#indistinct nucleoli and rosette-like structures
#9406
middle Confidence
Subject:
SCLC
(Tumor type)
→
is_characterized_by
→
Object:
indistinct_nucleoli
(Nuclear characteristics)
Original: SCLC#is characterized by#indistinct nucleoli and rosette-like structures
#9398
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological operation)
→
was_performed_for
→
Object:
bilateral_palpable_mammary_masses
(Tumor manifestations)
Original: Fine needle aspiration biopsy#was performed#for bilateral palpable mammary masses
#9376
middle Confidence
Subject:
CK20_positive_large_cell_neuroendocrine_carcinoma_of_colon
(Tumor type)
→
is_located_in
→
Object:
Ascending_colon
(organ)
Original: CK20-positive large cell neuroendocrine carcinoma of the colon#is located in#ascending colon
#9359
middle Confidence
Subject:
lung cells
(Lung cells)
→
was_biopsied_by
→
Object:
Tru-cut biopsy
(Diagnostic techniques)
Original: Tru-cut biopsy from the lung lesion#was performed#and histopathology was compatible with LCLC
#9302
middle Confidence
Subject:
multinucleate_giant_cell
(Cell Type)
→
is_present_in
→
Object:
Spitz_nevus
(disease)
Original: Both cases#contained#scattered multinucleate giant cells similar to those observed in classical form of Spitz nevi
#9269
middle Confidence
Subject:
Tumors
(Tumor type)
→
characterized_by
→
Object:
vesicular_nuclei
(Histological characteristics)
Original: Tumors#characterized by#epithelioid arrangement/ clear cytoplasm/ vesicular nuclei/ etc.
#9268
middle Confidence
Subject:
Tumors
(Tumor type)
→
characterized_by
→
Object:
clear_cytoplasm
(Histological characteristics)
Original: Tumors#characterized by#epithelioid arrangement/ clear cytoplasm/ vesicular nuclei/ etc.
#9267
middle Confidence
Subject:
Tumors
(Tumor type)
→
characterized_by
→
Object:
epithelioid_arrangement
(Histological characteristics)
Original: Tumors#characterized by#epithelioid arrangement/ clear cytoplasm/ vesicular nuclei/ etc.
#9266
middle Confidence
Subject:
Cytologic_findings_of_SCTATs
(Cytological characteristics)
→
are_distinct_from
→
Object:
rosette_like_structures_of_granulosa_cell_tumors
(Histological characteristics)
Original: Cytologic findings of SCTATs#are distinct from#rosette-like structures of granulosa-cell tumors
#9231
middle Confidence
Subject:
neuronal_cells
(Neuron-like cells)
→
show
→
Object:
positive_reactivity_to_met_enkephalin
(Immunophenotypic markers)
Original: Immunohistochemical studies#showed#cells reacting positively with antisera against neurone-specific enolase/ epithelial membrane antigen/ and met-enkephalin
#9230
middle Confidence
Subject:
neuronal_cells
(Neuron-like cells)
→
show
→
Object:
positive_reactivity_to_epithelial_membrane_antigen
(Immunophenotypic markers)
Original: Immunohistochemical studies#showed#cells reacting positively with antisera against neurone-specific enolase/ epithelial membrane antigen/ and met-enkephalin
#9229
middle Confidence
Subject:
neuronal_cells
(Neuron-like cells)
→
show
→
Object:
positive_reactivity_to_neuron_specific_enolase
(Immunophenotypic markers)
Original: Immunohistochemical studies#showed#cells reacting positively with antisera against neurone-specific enolase/ epithelial membrane antigen/ and met-enkephalin
#9223
middle Confidence
Subject:
AgNOR_count
(molecular staining signal)
→
increases_to
→
Object:
anaplastic_carcinoma
(Tumor tissue)
Original: A stepwise increase in nuclear size and AgNOR counts#from#normal thyroid tissue to follicular adenoma and anaplastic carcinoma
#9222
middle Confidence
Subject:
AgNOR_count
(molecular staining signal)
→
increases_to
→
Object:
follicular_adenoma
(Tumor tissue)
Original: A stepwise increase in nuclear size and AgNOR counts#from#normal thyroid tissue to follicular adenoma and anaplastic carcinoma
#9221
middle Confidence
Subject:
AgNOR_count
(molecular staining signal)
→
increases_from
→
Object:
normal_thyroid_tissue
(Normal tissue)
Original: A stepwise increase in nuclear size and AgNOR counts#from#normal thyroid tissue to follicular adenoma and anaplastic carcinoma
#9220
middle Confidence
Subject:
nuclear_size
(Nuclear morphology)
→
increases_to
→
Object:
anaplastic_carcinoma
(Tumor tissue)
Original: A stepwise increase in nuclear size and AgNOR counts#from#normal thyroid tissue to follicular adenoma and anaplastic carcinoma
#9219
middle Confidence
Subject:
nuclear_size
(Nuclear morphology)
→
increases_to
→
Object:
follicular_adenoma
(Tumor tissue)
Original: A stepwise increase in nuclear size and AgNOR counts#from#normal thyroid tissue to follicular adenoma and anaplastic carcinoma
#9218
middle Confidence
Subject:
nuclear_size
(Nuclear morphology)
→
increases_from
→
Object:
normal_thyroid_tissue
(Normal tissue)
Original: A stepwise increase in nuclear size and AgNOR counts#from#normal thyroid tissue to follicular adenoma and anaplastic carcinoma
#9217
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
nonmelanocytic_lesion_with_plexiform_growth_pattern
(Histopathological features)
Original: The differential diagnosis#includes#melanocytic and nonmelanocytic lesions exhibiting a plexiform pattern of growth
#9216
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
melanocytic_lesion_with_plexiform_growth_pattern
(Histopathological features)
Original: The differential diagnosis#includes#melanocytic and nonmelanocytic lesions exhibiting a plexiform pattern of growth
#9215
middle Confidence
Subject:
FNA_biopsy_specimens
(Fine needle aspiration biopsy specimen)
→
were_analyzed_to_identify
→
Object:
criteria_for_diagnosing_mucoepidermoid_carcinoma
(Diagnostic criteria)
Original: FNA biopsy specimens#were analyzed to identify#criteria for diagnosing mucoepidermoid carcinoma
#9214
middle Confidence
Subject:
Percutaneous_needle_biopsy
(Percutaneous needle biopsy)
→
showed
→
Object:
malignant_tumor_with_small_ovoid_cell_phenotype
(Malignant tumor phenotype)
Original: Percutaneous needle biopsy#showed#malignant tumor with "small ovoid cell" phenotype
#9213
middle Confidence
Subject:
Incisional_biopsy
(Incisional biopsy)
→
diagnosed
→
Object:
metastatic_ASPS
(Metastatic ASPS)
Original: Incisional biopsy#diagnosed#metastatic ASPS
#9212
middle Confidence
Subject:
Non-observance_of_preserved_cellular_samples
(Improper specimen storage)
→
leads_to
→
Object:
pitfalls_in_diagnosing_bronchogenic_carcinoma
(Diagnostic Error)
Original: Non-observance of preserved cellular samples#leads to#pitfalls in diagnosing bronchogenic carcinoma
#9211
middle Confidence
Subject:
Brush_cytopathologic_diagnoses
(Cytological diagnostic methods)
→
were_compared_with
→
Object:
biopsy_or_lobectomy_results
(Histopathological results)
Original: Brush cytopathologic diagnoses#were compared with#biopsy or lobectomy results
#9210
middle Confidence
Subject:
Morphologic_studies
(Morphological analysis methods)
→
analyzes
→
Object:
prostate_cancers
(disease)
Original: Morphologic studies#analyze#prostate cancers
#9209
middle Confidence
Subject:
nucleolar_grade
(Nuclear fractionation)
→
is_lower_in
→
Object:
NOCA_cases
(Atypical prostate cases)
Original: nucleolar grade#is higher in#PCA cases than NOCA cases
#9208
middle Confidence
Subject:
nucleolar_grade
(Nuclear fractionation)
→
is_higher_in
→
Object:
PCA_cases
(Prostate cancer cases)
Original: nucleolar grade#is higher in#PCA cases than NOCA cases
#9164
middle Confidence
Subject:
abnormal_cells
(Cell phenotype)
→
positive_for
→
Object:
holzer_stain
(Staining method)
Original: Abnormal cells#are positive for#glial fibrillary acidic protein (GFAP)/ Nissl/ and Holzer's stains
#9163
middle Confidence
Subject:
abnormal_cells
(Cell phenotype)
→
positive_for
→
Object:
nissl_stain
(Staining method)
Original: Abnormal cells#are positive for#glial fibrillary acidic protein (GFAP)/ Nissl/ and Holzer's stains
#9162
middle Confidence
Subject:
Immunohistochemistry
(Molecular analysis technology)
→
employed_for
→
Object:
CNS_studies
(Organizational Research)
Original: Histochemistry and immunohistochemistry#are employed for#CNS studies
#9161
middle Confidence
Subject:
histochemistry
(Molecular analysis technology)
→
employed_for
→
Object:
CNS_studies
(Organizational Research)
Original: Histochemistry and immunohistochemistry#are employed for#CNS studies
#9160
middle Confidence
Subject:
Cytopathology
(Cytological analysis)
→
described_by
→
Object:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
Original: Cytopathology#is described by#fine needle aspiration biopsy (FNAB)
#9147
middle Confidence
Subject:
retrospective_analysis
(Retrospective analysis)
→
was_performed_to_identify
→
Object:
helpful_feature_for_avoiding_misdiagnosis
(Diagnostic features)
Original: retrospective analysis#was performed to identify#features helpful for avoiding misdiagnosis
#9146
middle Confidence
Subject:
finding
(Diagnostic Findings)
→
is_diagnostic_of
→
Object:
plasmablastic_lymphoma
(Tumor diseases)
Original: findings#are diagnostic of#plasmablastic lymphoma
#9131
middle Confidence
Subject:
cervical_smears
(Cytology samples)
→
form
→
Object:
materials_for_VGA_study
(Research Materials)
Original: cervical smears#form#materials for VGA study
#9128
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Rhabdomyosarcoma
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9127
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Angiosarcoma
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9126
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Malignant_fibrous_histiocytoma
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9125
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Epithelioid_sarcoma
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9124
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Trophoblastic_tumor
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9123
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Large_cell_anaplastic_lymphoma
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9122
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Hodgkin's_disease
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9121
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Malignant_melanoma
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9120
middle Confidence
Subject:
Differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Metastatic_carcinoma
(Tumor diseases)
Original: Differential diagnosis#includes#metastatic carcinoma/ malignant melanoma/ Hodgkin's disease/ large cell anaplastic lymphoma/ trophoblastic tumor/ epithelioid sarcoma/ malignant fibrous histiocytoma/ angiosarcoma/ rhabdomyosarcoma
#9104
middle Confidence
Subject:
Pleomorphic_hyalinizing_angiectatic_tumor
(Tumor type)
→
is_characterized_by
→
Object:
pleomorphic_cells
(Cell Type)
Original: Pleomorphic hyalinizing angiectatic tumor (PHAT)#is characterized by#bland spindle cells and pleomorphic cells
#9103
middle Confidence
Subject:
Pleomorphic_hyalinizing_angiectatic_tumor
(Tumor type)
→
is_characterized_by
→
Object:
bland_spindle_cells
(Cell Type)
Original: Pleomorphic hyalinizing angiectatic tumor (PHAT)#is characterized by#bland spindle cells and pleomorphic cells
#9094
middle Confidence
Subject:
pseudo-smooth_muscle_actin
(Protein markers)
→
indicates
→
Object:
myogenic_differentiation
(Cell differentiation type)
Original: �?smooth muscle actin#indicates#myogenic differentiation
#9081
middle Confidence
Subject:
Thyroid_carcinoma
(Tumor)
→
underwent
→
Object:
preoperative_fine_needle_aspiration_cytology
(Technical methods)
Original: Four cases of poorly differentiated thyroid carcinoma#underwent#preoperative fine needle aspiration cytology
#9080
middle Confidence
Subject:
Dendritic_melanocytes
(Melanocytes)
→
are_identified_by
→
Object:
HMB-45
(Cell markers)
Original: Dendritic melanocytes#were identified by#S-100 protein and HMB-45 immunohistochemically
#9079
middle Confidence
Subject:
Dendritic_melanocytes
(Melanocytes)
→
are_identified_by
→
Object:
S-100_protein
(Cell markers)
Original: Dendritic melanocytes#were identified by#S-100 protein and HMB-45 immunohistochemically
#9078
middle Confidence
Subject:
Pigmented_carcinoma_cells
(Tumor cells)
→
are_positive_for
→
Object:
CAM5.2
(Cell markers)
Original: Pigmented carcinoma cells#were#low molecular weight cytokeratin (CAM5.2) positive
#9060
middle Confidence
Subject:
tumors
(Tumor tissue)
→
were_located_in
→
Object:
suprasellar_region
(Anatomical location)
Original: Tumors#were located in#hypophysis and suprasellar region
#9059
middle Confidence
Subject:
tumors
(Tumor tissue)
→
were_located_in
→
Object:
hypophysis
(organ)
Original: Tumors#were located in#hypophysis and suprasellar region
#9050
middle Confidence
Subject:
patient
(Patient characteristics)
→
was_diagnosed_with
→
Object:
pulmonary_consolidation
(Clinical symptoms)
Original: The patient#was diagnosed to have#right-sided pulmonary consolidation
#9025
middle Confidence
Subject:
tests
(Diagnostic Methods)
→
revealed
→
Object:
bare_nuclei
(Cell morphology)
Original: Tests#revealed#relatively frequent single malignant cells and bare nuclei
#9024
middle Confidence
Subject:
tests
(Diagnostic Methods)
→
revealed
→
Object:
frequent_single_malignant_cells
(Cell morphology)
Original: Tests#revealed#relatively frequent single malignant cells and bare nuclei
#9023
middle Confidence
Subject:
nine_smears
(sample)
→
were_diagnosed_as
→
Object:
positive_for_malignancy
(Diagnosis conclusion)
Original: Nine smears#were diagnosed as#positive for malignancy
#9014
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
revealed
→
Object:
large_electron-lucent_nuclei
(Cell structure)
Original: tumor cells#revealed#large electron-lucent nuclei with irregular outlines
#9013
middle Confidence
Subject:
cytologic_features
(Cell morphology)
→
showed
→
Object:
thymoma_with_intermediate_cytology
(Tumor subtype)
Original: cytologic features#showed#thymoma with intermediate cytology between ordinary thymoma and thymic carcinoma
#9012
middle Confidence
Subject:
atypical_cytologic_features
(Cell morphology)
→
causes
→
Object:
diagnostic_confusion_with_thymic_carcinoma
(Diagnostic difficulties)
Original: atypical cytologic features#caused#diagnostic confusion with thymic carcinoma
#9001
middle Confidence
Subject:
case
(Case)
→
consisted_of
→
Object:
AHCs
(Cell Type)
Original: 7 cases#consisted of#only AHCs in metastatic PTC in LNs
#9000
middle Confidence
Subject:
case
(Case)
→
showed
→
Object:
classic_PTC
(Cell Type)
Original: 31 cases#showed#mixed AHCs and classic PTC
#8999
middle Confidence
Subject:
case
(Case)
→
showed
→
Object:
AHCs
(Cell Type)
Original: 31 cases#showed#mixed AHCs and classic PTC
#8998
middle Confidence
Subject:
VGA
(Cell Type)
→
shares_morphologic_similarity_with
→
Object:
reactive_endocervical_cells
(Cell Type)
Original: VGA#shares#morphologic similarities with adenocarcinoma in situ/ squamous cell carcinoma in situ/ endometrial cells/ and reactive endocervical cells
#8997
middle Confidence
Subject:
VGA
(Cell Type)
→
shares_morphologic_similarity_with
→
Object:
endometrial_cells
(Cell Type)
Original: VGA#shares#morphologic similarities with adenocarcinoma in situ/ squamous cell carcinoma in situ/ endometrial cells/ and reactive endocervical cells
#8996
middle Confidence
Subject:
VGA
(Cell Type)
→
shares_morphologic_similarity_with
→
Object:
squamous_cell_carcinoma_in_situ
(Cell Type)
Original: VGA#shares#morphologic similarities with adenocarcinoma in situ/ squamous cell carcinoma in situ/ endometrial cells/ and reactive endocervical cells
#8995
middle Confidence
Subject:
VGA
(Cell Type)
→
shares_morphologic_similarity_with
→
Object:
adenocarcinoma_in_situ
(Cell Type)
Original: VGA#shares#morphologic similarities with adenocarcinoma in situ/ squamous cell carcinoma in situ/ endometrial cells/ and reactive endocervical cells
#8975
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
lymphoma
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8974
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
malignant_neuroepithelial_tumor
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8973
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
rhabdomyosarcoma
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8972
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
oncocytoma
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8971
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
collecting_duct_carcinoma
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8970
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
transitional_cell_carcinoma
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8969
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
renal_cell_carcinoma
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8968
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
congenital_mesoblastic_nephroma
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8967
middle Confidence
Subject:
diverse_group_of_neoplasms
(Tumor)
→
includes
→
Object:
anaplastic_Wilms_tumor
(Tumor)
Original: Diverse group of neoplasms#included#anaplastic Wilms' tumor/ congenital mesoblastic nephroma/ renal cell carcinoma/ transitional cell carcinoma/ collecting-duct carcinoma/ oncocytoma/ rhabdomyosarcoma/ malignant neuroepithelial tumors/ and lymphoma
#8966
middle Confidence
Subject:
renal_lesion
(Kidney disease)
→
consists_of
→
Object:
diverse_group_of_neoplasms
(Tumor)
Original: Other 40 renal lesions mimicking rhabdoid tumor of kidney#consisted of#clinically and histogenetically diverse group of neoplasms
#8965
middle Confidence
Subject:
PAS_stain
(Dyeing technology)
→
shows
→
Object:
coarse_granular_positive_or_negative
(Staining reaction)
Original: Periodic acid-Schiff (PAS) stain#was#negative or positive with a form of coarse granules
#8964
middle Confidence
Subject:
eccrine_glandular_or_ductal_structures
(Glandular structure)
→
are_lacking_in
→
Object:
carcinoma_cells
(Tumor cells)
Original: Structures#characteristical for#eccrine glandular or ductal differentiation were lacking
#8929
middle Confidence
Subject:
4-stain_immunopanel
(Immunohistochemistry)
→
assists_in_subclassifying
→
Object:
LCC
(disease)
Original: The 4-stain immunopanel#might help subclassify#LCC even in small biopsy material
#8926
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed
→
Object:
rhabdoid_features
(Cell morphology phenotype)
Original: Tumor cells#showed#rhabdoid features
#8916
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrated
→
Object:
clusters_of_monomorphic_plasmacytoid_cells
(Cell morphology phenotype)
Original: Cellular smears#demonstrated#clusters and single monomorphic plasmacytoid tumor cells
#8915
middle Confidence
Subject:
mass
(Tumor Entities)
→
shows
→
Object:
well-demarcated_tan_white_tumor
(Tumor morphology phenotype)
Original: Gross examination of the mass#showed#a well-demarcated/ tan/ white tumor
#8907
middle Confidence
Subject:
peritoneal_fluid_cytology
(Cytological analysis)
→
differs_from
→
Object:
endometrial_cytology
(Cytological analysis)
Original: Features of cervical smears and peritoneal fluid cytology#differed from#those of endometrial cytology
#8906
middle Confidence
Subject:
cervical_smear_cytology
(Cytological analysis)
→
differs_from
→
Object:
endometrial_cytology
(Cytological analysis)
Original: Features of cervical smears and peritoneal fluid cytology#differed from#those of endometrial cytology
#8846
middle Confidence
Subject:
Histologic_material
(Histological materials)
→
reveals
→
Object:
elements_identified_on_aspiration_smears
(Cytological elements)
Original: Histologic material#reveals#elements identified cytologically on aspiration smears
#8844
middle Confidence
Subject:
Cribriform_pattern_of_tumor
(Tumor tissue morphology)
→
prompts
→
Object:
search_for_metastasis
(Diagnostic behavior)
Original: Cribriform pattern of the tumor#prompted#search for metastasis from other sites
#8828
middle Confidence
Subject:
large_loosely_cohesive_cells
(Cell population)
→
are_characterized_by
→
Object:
prominent_central_nucleoli
(Nuclear structure)
Original: large/ loosely cohesive cells#are characterized by#prominent central nucleoli
#8827
middle Confidence
Subject:
nucleoli
(Nuclear structure)
→
are_characterized_by
→
Object:
increased_nuclear_cytoplasmic_ratio
(Cell morphology)
Original: nucleoli#are characterized by#increased nuclear/cytoplasmic ratio
#8826
middle Confidence
Subject:
TP53
(Tumor suppressor proteins)
→
exhibits
→
Object:
overexpression_in_some_cases
(Overexpression)
Original: p53#exhibits#either absence or overexpression in virus-negative cases
#8825
middle Confidence
Subject:
TP53
(Tumor suppressor proteins)
→
exhibits
→
Object:
absence_in_some_cases
(Loss of expression)
Original: p53#exhibits#either absence or overexpression in virus-negative cases
#8823
middle Confidence
Subject:
Laboratory_tests
(Laboratory testing)
→
revealed
→
Object:
abnormal_beta-2_microglobulin_level
(Biochemical indicators)
Original: Laboratory tests#revealed#abnormal levels of alanine aminotransferase/ lactate dehydrogenase/ and beta-2 microglobulin
#8822
middle Confidence
Subject:
Laboratory_tests
(Laboratory testing)
→
revealed
→
Object:
abnormal_lactate_dehydrogenase_level
(Biochemical indicators)
Original: Laboratory tests#revealed#abnormal levels of alanine aminotransferase/ lactate dehydrogenase/ and beta-2 microglobulin
#8821
middle Confidence
Subject:
Laboratory_tests
(Laboratory testing)
→
revealed
→
Object:
abnormal_alanine_aminotransferase_level
(Biochemical indicators)
Original: Laboratory tests#revealed#abnormal levels of alanine aminotransferase/ lactate dehydrogenase/ and beta-2 microglobulin
#8820
middle Confidence
Subject:
Neoplasm
(Tumor)
→
lacks
→
Object:
lateral_intramucosal_spread
(Pathological characteristics)
Original: Neoplasm#extended#directly down into the submucosa without lateral intramucosal spread
#8819
middle Confidence
Subject:
Neoplasm
(Tumor)
→
extends_into
→
Object:
submucosa
(Organizational Structure)
Original: Neoplasm#extended#directly down into the submucosa without lateral intramucosal spread
#8802
middle Confidence
Subject:
clinicopathologic_features
(Clinicopathological characteristics)
→
described_in
→
Object:
SMARCA4_mutation_case
(Gene mutation cases)
Original: Clinicopathologic features of esophageal carcinoma#were described in#four cases with SMARCA4 mutation
#8776
middle Confidence
Subject:
medical_carcinoma_of_thyroid
(Tumor)
→
was_reviewed_for
→
Object:
atypical_cytologic_features
(Cytological characteristics)
Original: Medullary carcinoma of the thyroid#was reviewed for#atypical cytologic features
#8775
middle Confidence
Subject:
smooth_muscle_cells
(Smooth muscle cells)
→
are_component_of
→
Object:
poorly_circumscribed_tumor
(Tumor)
Original: Smooth muscle cells with bizarre and pleomorphic nuclei#were composed of#a poorly circumscribed tumor
#8774
middle Confidence
Subject:
smooth_muscle_cells
(Smooth muscle cells)
→
display
→
Object:
pleomorphic_nuclei
(Nuclear morphology)
Original: Smooth muscle cells with bizarre and pleomorphic nuclei#were composed of#a poorly circumscribed tumor
#8715
middle Confidence
Subject:
High-grade_tumor_cases
(Tumor Cases)
→
showed
→
Object:
median_21_mitoses_per_10_HPFs
(Proliferation activity)
Original: All cases#were high-grade showing#necrosis/ prominent nucleoli/ and median 21 mitoses/10 HPFs
#8714
middle Confidence
Subject:
High-grade_tumor_cases
(Tumor Cases)
→
showed
→
Object:
prominent_nucleoli
(Cell morphology)
Original: All cases#were high-grade showing#necrosis/ prominent nucleoli/ and median 21 mitoses/10 HPFs
#8713
middle Confidence
Subject:
High-grade_tumor_cases
(Tumor Cases)
→
showed
→
Object:
Necrosis
(Histopathological characteristics)
Original: All cases#were high-grade showing#necrosis/ prominent nucleoli/ and median 21 mitoses/10 HPFs
#8700
middle Confidence
Subject:
MRI
(Imaging Technology)
→
showed
→
Object:
ring_enhancement_on_clear_margin_mass
(Imaging features)
Original: CT and MRI studies#showed#ring enhancement on a clear margin mass in the right parieto-occipital lobe
#8699
middle Confidence
Subject:
CT
(Imaging Technology)
→
showed
→
Object:
ring_enhancement_on_clear_margin_mass
(Imaging features)
Original: CT and MRI studies#showed#ring enhancement on a clear margin mass in the right parieto-occipital lobe
#8690
middle Confidence
Subject:
Immunohistochemistry
(Detection Technology)
→
compared_with
→
Object:
primary_CNS_malignant_rhabdoid_tumors
(Tumor)
Original: Immunohistochemical/ light/ and electron microscopic features#are compared with#primary CNS malignant rhabdoid tumors reported in literature
#8657
middle Confidence
Subject:
endoscopic_examination
(Endoscopy)
→
suggests
→
Object:
malignancy
(Malignant tumors)
Original: Endoscopic examination#revealed#a tumorous lesion suspicious of malignancy
#8656
middle Confidence
Subject:
endoscopic_examination
(Endoscopy)
→
reveals
→
Object:
tumorous_lesion
(Tumor lesions)
Original: Endoscopic examination#revealed#a tumorous lesion suspicious of malignancy
#8655
middle Confidence
Subject:
fine-needle_aspiration_smear
(Cytology)
→
reveals
→
Object:
prominent_nucleoli
(Nuclear morphology)
Original: Fine-needle aspiration smears#revealed#round to polygonal cells with vesicular nuclei and prominent nucleoli
#8654
middle Confidence
Subject:
fine-needle_aspiration_smear
(Cytology)
→
reveals
→
Object:
vesicular_nuclei
(Nuclear morphology)
Original: Fine-needle aspiration smears#revealed#round to polygonal cells with vesicular nuclei and prominent nucleoli
#8653
middle Confidence
Subject:
fine-needle_aspiration_smear
(Cytology)
→
reveals
→
Object:
round_to_polygonal_cells
(Cell morphology)
Original: Fine-needle aspiration smears#revealed#round to polygonal cells with vesicular nuclei and prominent nucleoli
#8645
middle Confidence
Subject:
spindle_cells
(Cell Type)
→
have
→
Object:
abundant_cytoplasm
(Cytoplasm)
Original: The neoplasm#was composed of#spindle cells with elongated or round nuclei/ prominent nucleoli and abundant cytoplasm
#8644
middle Confidence
Subject:
spindle_cells
(Cell Type)
→
have
→
Object:
prominent_nucleoli
(Nuclear components)
Original: The neoplasm#was composed of#spindle cells with elongated or round nuclei/ prominent nucleoli and abundant cytoplasm
#8643
middle Confidence
Subject:
spindle_cells
(Cell Type)
→
have
→
Object:
round_nuclei
(Nuclear morphology)
Original: The neoplasm#was composed of#spindle cells with elongated or round nuclei/ prominent nucleoli and abundant cytoplasm
#8642
middle Confidence
Subject:
spindle_cells
(Cell Type)
→
have
→
Object:
elongated_nuclei
(Nuclear morphology)
Original: The neoplasm#was composed of#spindle cells with elongated or round nuclei/ prominent nucleoli and abundant cytoplasm
#8641
middle Confidence
Subject:
neoplasm
(Tumor type)
→
is_composed_of
→
Object:
spindle_cells
(Cell Type)
Original: The neoplasm#was composed of#spindle cells with elongated or round nuclei/ prominent nucleoli and abundant cytoplasm
#8621
middle Confidence
Subject:
AgNOR_number_per_cell
(Cytological indicators)
→
reveals
→
Object:
overlap_between_FA_and_PTLGM
(Disease phenotype)
Original: AgNOR number per cell#revealed#overlap between FA and PTLGM
#8603
middle Confidence
Subject:
small_tissue_fragment
(Tissue specimens)
→
showed
→
Object:
well-cohesive_clusters_of_uniform_tumor_cells
(Cell morphology)
Original: small tissue fragment#showed#medium- to large-sized/ well-cohesive clusters or sheets of uniform tumor cells
#8602
middle Confidence
Subject:
monoclonal_antibody_against_epithelial_membrane_antigen_EMA
(Monoclonal antibodies)
→
is_included_in
→
Object:
epithelial_derivation_antibodies
(Antibody Class)
Original: Epithelial derivation antibodies#include#anti-keratin monoclonal antibody AE1/AE3/ polyclonal anti-keratin/ monoclonal anti-cytokeratin cocktail (MAK-6)/ and monoclonal antibody against epithelial membrane antigen (EMA)
#8601
middle Confidence
Subject:
monoclonal_anti-cytokeratin_cocktail_MAK-6
(Monoclonal antibodies)
→
is_included_in
→
Object:
epithelial_derivation_antibodies
(Antibody Class)
Original: Epithelial derivation antibodies#include#anti-keratin monoclonal antibody AE1/AE3/ polyclonal anti-keratin/ monoclonal anti-cytokeratin cocktail (MAK-6)/ and monoclonal antibody against epithelial membrane antigen (EMA)
#8600
middle Confidence
Subject:
polyclonal_anti-keratin
(Polyclonal antibodies)
→
is_included_in
→
Object:
epithelial_derivation_antibodies
(Antibody Class)
Original: Epithelial derivation antibodies#include#anti-keratin monoclonal antibody AE1/AE3/ polyclonal anti-keratin/ monoclonal anti-cytokeratin cocktail (MAK-6)/ and monoclonal antibody against epithelial membrane antigen (EMA)
#8599
middle Confidence
Subject:
anti-keratin_monoclonal_antibody_AE1/AE3
(Monoclonal antibodies)
→
is_included_in
→
Object:
epithelial_derivation_antibodies
(Antibody Class)
Original: Epithelial derivation antibodies#include#anti-keratin monoclonal antibody AE1/AE3/ polyclonal anti-keratin/ monoclonal anti-cytokeratin cocktail (MAK-6)/ and monoclonal antibody against epithelial membrane antigen (EMA)
#8594
middle Confidence
Subject:
multiloculated_thymic_cysts
(Cystic lesions)
→
can_be
→
Object:
associated_with_malignancies
(Malignant tumor related)
Original: Multiloculated thymic cysts#can be#either acquired or associated with malignancies
#8590
middle Confidence
Subject:
HMB-45
(Protein markers)
→
is_evaluated_by
→
Object:
Immunostaining
(Detection Technology)
Original: immunostaining with S-100 or HMB-45#was evaluated#in 6 of 11 cases
#8589
middle Confidence
Subject:
S-100
(Protein markers)
→
is_evaluated_by
→
Object:
Immunostaining
(Detection Technology)
Original: immunostaining with S-100 or HMB-45#was evaluated#in 6 of 11 cases
#8578
middle Confidence
Subject:
physical_examination
(Clinical examination)
→
revealed
→
Object:
lymphadenopathy
(Clinical symptoms)
Original: Physical examination#revealed#marked hepatosplenomegaly with ascites and lymphadenopathy
#8577
middle Confidence
Subject:
physical_examination
(Clinical examination)
→
revealed
→
Object:
ascites
(Clinical symptoms)
Original: Physical examination#revealed#marked hepatosplenomegaly with ascites and lymphadenopathy
#8576
middle Confidence
Subject:
physical_examination
(Clinical examination)
→
revealed
→
Object:
marked_hepatosplenomegaly
(Clinical symptoms)
Original: Physical examination#revealed#marked hepatosplenomegaly with ascites and lymphadenopathy
#8575
middle Confidence
Subject:
patient_with_ALCL
(Patient characteristics)
→
demonstrates
→
Object:
circulating_lymphoma_cells
(Tumor cell type)
Original: Patient with ALCL#demonstrates#circulating lymphoma cells
#8574
middle Confidence
Subject:
Lesions
(Histopathological structure)
→
characterized_by
→
Object:
noncohesive_aggregates_of_large_neoplastic_cells_with_abundant_eosinophilic_cytoplasm_and_conspicuous_nucleoli
(Histopathological characteristics)
Original: Lesions#were characterized by#noncohesive aggregates of large neoplastic cells with abundant eosinophilic cytoplasm and conspicuous nucleoli
#8573
middle Confidence
Subject:
Acantholytic_cells_(Tzanck_cells)
(Cell Type)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: Acantholytic cells (Tzanck cells)#are characterized by#amoeboid-like cytoplasmic projections/ eosinophils/ basophils/ lymphocytes with irregular nuclear borders/ cerebriform nuclei/ and prominent nucleoli
#8572
middle Confidence
Subject:
Acantholytic_cells_(Tzanck_cells)
(Cell Type)
→
are_characterized_by
→
Object:
cerebriform_nuclei
(Nuclear characteristics)
Original: Acantholytic cells (Tzanck cells)#are characterized by#amoeboid-like cytoplasmic projections/ eosinophils/ basophils/ lymphocytes with irregular nuclear borders/ cerebriform nuclei/ and prominent nucleoli
#8571
middle Confidence
Subject:
Acantholytic_cells_(Tzanck_cells)
(Cell Type)
→
are_characterized_by
→
Object:
lymphocytes_with_irregular_nuclear_borders
(Nuclear characteristics)
Original: Acantholytic cells (Tzanck cells)#are characterized by#amoeboid-like cytoplasmic projections/ eosinophils/ basophils/ lymphocytes with irregular nuclear borders/ cerebriform nuclei/ and prominent nucleoli
#8570
middle Confidence
Subject:
Acantholytic_cells_(Tzanck_cells)
(Cell Type)
→
are_characterized_by
→
Object:
basophils
(Cell infiltration)
Original: Acantholytic cells (Tzanck cells)#are characterized by#amoeboid-like cytoplasmic projections/ eosinophils/ basophils/ lymphocytes with irregular nuclear borders/ cerebriform nuclei/ and prominent nucleoli
#8569
middle Confidence
Subject:
Acantholytic_cells_(Tzanck_cells)
(Cell Type)
→
are_characterized_by
→
Object:
Eosinophils
(Cell infiltration)
Original: Acantholytic cells (Tzanck cells)#are characterized by#amoeboid-like cytoplasmic projections/ eosinophils/ basophils/ lymphocytes with irregular nuclear borders/ cerebriform nuclei/ and prominent nucleoli
#8568
middle Confidence
Subject:
Acantholytic_cells_(Tzanck_cells)
(Cell Type)
→
are_characterized_by
→
Object:
amoeboid-like_cytoplasmic_projections
(Cell morphology)
Original: Acantholytic cells (Tzanck cells)#are characterized by#amoeboid-like cytoplasmic projections/ eosinophils/ basophils/ lymphocytes with irregular nuclear borders/ cerebriform nuclei/ and prominent nucleoli
#8567
middle Confidence
Subject:
Patients_with_skin_bullous_disease
(Patient population)
→
are_suspected_of_having
→
Object:
Pemphigus_vulgaris
(disease)
Original: Patients with skin bullous disease#are suspected of having#Pemphigus vulgaris
#8566
middle Confidence
Subject:
Skin_cells
(Skin cells)
→
are_associated_with
→
Object:
pitfalls
(Diagnostic Pitfalls)
Original: Pemphigus vulgaris of skin#is associated with#cytological findings and pitfalls
#8565
middle Confidence
Subject:
Skin_cells
(Skin cells)
→
are_associated_with
→
Object:
cytological_findings
(Cytological manifestations)
Original: Pemphigus vulgaris of skin#is associated with#cytological findings and pitfalls
#8564
middle Confidence
Subject:
Blasts
(Hematopoietic cells)
→
lack_expression_of
→
Object:
myeloperoxidase
(Enzymes)
Original: Blasts#exhibit#strong staining for hemoglobin and lack expression of Factor VIII and myeloperoxidase
#8563
middle Confidence
Subject:
Blasts
(Hematopoietic cells)
→
lack_expression_of
→
Object:
Factor_VIII
(Intracellular proteins)
Original: Blasts#exhibit#strong staining for hemoglobin and lack expression of Factor VIII and myeloperoxidase
#8562
middle Confidence
Subject:
Blasts
(Hematopoietic cells)
→
exhibit
→
Object:
strong_staining_for_hemoglobin
(Intracellular proteins)
Original: Blasts#exhibit#strong staining for hemoglobin and lack expression of Factor VIII and myeloperoxidase
#8561
middle Confidence
Subject:
Blast forms
(Cell Type)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: Blast forms#are characterized by#large round nuclei with finely dispersed chromatin and prominent nucleoli
#8560
middle Confidence
Subject:
Blast forms
(Cell Type)
→
are_characterized_by
→
Object:
finely_dispersed_chromatin
(Chromatin characteristics)
Original: Blast forms#are characterized by#large round nuclei with finely dispersed chromatin and prominent nucleoli
#8559
middle Confidence
Subject:
Blast forms
(Cell Type)
→
are_characterized_by
→
Object:
large_round_nuclei
(Nuclear characteristics)
Original: Blast forms#are characterized by#large round nuclei with finely dispersed chromatin and prominent nucleoli
#8558
middle Confidence
Subject:
Epithelioid-like cells
(Cell Type)
→
are_characterized_by
→
Object:
vesicular_nuclei
(Nuclear characteristics)
Original: Epithelioid-like cells#are characterized by#eosinophilic cytoplasm/ prominent nucleoli/ and vesicular nuclei
#8557
middle Confidence
Subject:
Epithelioid-like cells
(Cell Type)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: Epithelioid-like cells#are characterized by#eosinophilic cytoplasm/ prominent nucleoli/ and vesicular nuclei
#8556
middle Confidence
Subject:
Epithelioid-like cells
(Cell Type)
→
are_characterized_by
→
Object:
eosinophilic_cytoplasm
(Cell morphology)
Original: Epithelioid-like cells#are characterized by#eosinophilic cytoplasm/ prominent nucleoli/ and vesicular nuclei
#8555
middle Confidence
Subject:
Benign monocytoid B cells
(B cell subtypes)
→
are_associated_with
→
Object:
lymphadenitis
(Lymph node inflammation)
Original: Benign monocytoid B cells#are seen in#lymph nodes in different types of lymphadenitis
#8554
middle Confidence
Subject:
Benign monocytoid B cells
(B cell subtypes)
→
are_seen_in
→
Object:
lymph_nodes
(Lymph node tissue)
Original: Benign monocytoid B cells#are seen in#lymph nodes in different types of lymphadenitis
#8544
middle Confidence
Subject:
neoplasms
(Tumor)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Cell nucleolus morphology)
Original: Neoplasms#were characterized by#large/ oval/ polygonal/ or spindled melanocytes with prominent nucleoli
#8543
middle Confidence
Subject:
neoplasms
(Tumor)
→
are_characterized_by
→
Object:
spindled_melanocytes
(Cell morphology)
Original: Neoplasms#were characterized by#large/ oval/ polygonal/ or spindled melanocytes with prominent nucleoli
#8542
middle Confidence
Subject:
neoplasms
(Tumor)
→
are_characterized_by
→
Object:
polygonal_melanocytes
(Cell morphology)
Original: Neoplasms#were characterized by#large/ oval/ polygonal/ or spindled melanocytes with prominent nucleoli
#8541
middle Confidence
Subject:
neoplasms
(Tumor)
→
are_characterized_by
→
Object:
oval_melanocytes
(Cell morphology)
Original: Neoplasms#were characterized by#large/ oval/ polygonal/ or spindled melanocytes with prominent nucleoli
#8540
middle Confidence
Subject:
neoplasms
(Tumor)
→
are_characterized_by
→
Object:
large_melanocytes
(Cell size)
Original: Neoplasms#were characterized by#large/ oval/ polygonal/ or spindled melanocytes with prominent nucleoli
#8538
middle Confidence
Subject:
malignant_neoplasm
(Malignant tumors)
→
is_characterized_by
→
Object:
prominent_nucleoli
(Cell nucleolus morphology)
Original: Biopsy#revealed#malignant neoplasm with large/ pleomorphic cells and prominent nucleoli
#8537
middle Confidence
Subject:
malignant_neoplasm
(Malignant tumors)
→
is_characterized_by
→
Object:
pleomorphic_cells
(Cellular atypia)
Original: Biopsy#revealed#malignant neoplasm with large/ pleomorphic cells and prominent nucleoli
#8536
middle Confidence
Subject:
malignant_neoplasm
(Malignant tumors)
→
is_characterized_by
→
Object:
large_cells
(Cell size)
Original: Biopsy#revealed#malignant neoplasm with large/ pleomorphic cells and prominent nucleoli
#8535
middle Confidence
Subject:
Biopsy
(Clinical operation)
→
revealed
→
Object:
malignant_neoplasm
(Malignant tumors)
Original: Biopsy#revealed#malignant neoplasm with large/ pleomorphic cells and prominent nucleoli
#8534
middle Confidence
Subject:
14-year-old_boy
(Patient characteristics)
→
presented_with
→
Object:
raised_serum_beta-HCG_level
(Abnormal biochemical indexes)
Original: 14-year-old boy#presented with#right inguinal mass and raised serum beta-HCG level
#8533
middle Confidence
Subject:
14-year-old_boy
(Patient characteristics)
→
presented_with
→
Object:
right_inguinal_mass
(Clinical symptoms)
Original: 14-year-old boy#presented with#right inguinal mass and raised serum beta-HCG level
#8532
middle Confidence
Subject:
Lymphoma
(Tumor diseases)
→
is_characterized_by
→
Object:
atypical_lymphoid_cells
(Abnormal lymphocytes)
Original: Lymphoma#was characterized by#hypercellular specimens with atypical lymphoid cells
#8531
middle Confidence
Subject:
Lymphoma
(Tumor diseases)
→
is_characterized_by
→
Object:
hypercellular_specimens
(Histopathological phenotype)
Original: Lymphoma#was characterized by#hypercellular specimens with atypical lymphoid cells
#8488
middle Confidence
Subject:
Imaging_studies
(Medical Imaging)
→
revealed
→
Object:
mass_in_right_sphenoid_sinus
(Tumor morphology)
Original: Imaging studies#revealed#a mass filling the right sphenoid sinus and eroding into adjacent sinuses and temporal bone
#8475
middle Confidence
Subject:
NECs
(Neuroendocrine tumor cells)
→
show
→
Object:
discrete_round_to_oval_cells_with_moderate_cytoplasm
(Cell morphology)
Original: NECs predominantly#show#discrete round to oval cells with moderate cytoplasm
#8444
middle Confidence
Subject:
Histopathological_examination
(Diagnostic techniques)
→
showed
→
Object:
medium_to_large_cells_with_vesicular_nuclei
(Cell morphology)
Original: Histopathological examination#showed#medium to large cells with vesicular nuclei
#8441
middle Confidence
Subject:
Differentiated_dysplasia
(Histopathological phenotype)
→
shows
→
Object:
increased_nucleoli_size
(Nucleolus enlargement)
Original: Differentiated dysplasia#showed#abnormal variation in nuclear size and shape/ increased nucleoli size
#8440
middle Confidence
Subject:
Differentiated_dysplasia
(Histopathological phenotype)
→
shows
→
Object:
abnormal_variation_in_nuclear_size_and_shape
(Abnormal nuclear morphology)
Original: Differentiated dysplasia#showed#abnormal variation in nuclear size and shape/ increased nucleoli size
#8422
middle Confidence
Subject:
tumor
(Tumor tissue)
→
exhibits
→
Object:
light_microscopic_features_of_typical_rhabdoid_tumor
(Histological phenotype)
Original: Tumor#exhibits#light microscopic features of a typical rhabdoid tumor
#8421
middle Confidence
Subject:
Cytomorphology
(Cell morphology)
→
presents
→
Object:
difficult_differential_diagnosis
(Diagnostic Process)
Original: Cytomorphology#presents#a difficult differential diagnosis with pleomorphic adenoma
#8410
middle Confidence
Subject:
pregnant_women
(Patient characteristics)
→
underwent
→
Object:
fine-needle_aspiration_biopsy
(Diagnostic techniques)
Original: pregnant women#underwent#fine-needle aspiration biopsies
#8409
middle Confidence
Subject:
histologic_findings
(Histological findings)
→
found_in
→
Object:
benign_melanocytic_nevi
(disease)
Original: histologic findings#also found in#lichen planus and regressing benign melanocytic nevi
#8408
middle Confidence
Subject:
histologic_findings
(Histological findings)
→
found_in
→
Object:
lichen_planus
(disease)
Original: histologic findings#also found in#lichen planus and regressing benign melanocytic nevi
#8357
middle Confidence
Subject:
type_A_thymoma
(Tumor tissue)
→
has
→
Object:
cytologic_differential_diagnosis
(Diagnostic Process)
Original: type A thymoma#has#cytologic differential diagnosis and prognostic aspects
#8332
middle Confidence
Subject:
Acral_myxoinflammatory_fibroblastic_sarcoma
(Tumor type)
→
exhibits
→
Object:
inflammatory_infiltrate
(Organizational structure characteristics)
Original: Tumors#exhibited#a multinodular configuration with infiltrative margins/ myxoid and fibrotic zones/ pleomorphic cells/ and inflammatory infiltrate
#8331
middle Confidence
Subject:
Acral_myxoinflammatory_fibroblastic_sarcoma
(Tumor type)
→
exhibits
→
Object:
pleomorphic_cells
(Cell morphology)
Original: Tumors#exhibited#a multinodular configuration with infiltrative margins/ myxoid and fibrotic zones/ pleomorphic cells/ and inflammatory infiltrate
#8330
middle Confidence
Subject:
Acral_myxoinflammatory_fibroblastic_sarcoma
(Tumor type)
→
exhibits
→
Object:
fibrotic_zones
(Organizational structure characteristics)
Original: Tumors#exhibited#a multinodular configuration with infiltrative margins/ myxoid and fibrotic zones/ pleomorphic cells/ and inflammatory infiltrate
#8329
middle Confidence
Subject:
Acral_myxoinflammatory_fibroblastic_sarcoma
(Tumor type)
→
exhibits
→
Object:
myxoid_zones
(Organizational structure characteristics)
Original: Tumors#exhibited#a multinodular configuration with infiltrative margins/ myxoid and fibrotic zones/ pleomorphic cells/ and inflammatory infiltrate
#8328
middle Confidence
Subject:
Acral_myxoinflammatory_fibroblastic_sarcoma
(Tumor type)
→
exhibits
→
Object:
infiltrative_margins
(Organizational structure characteristics)
Original: Tumors#exhibited#a multinodular configuration with infiltrative margins/ myxoid and fibrotic zones/ pleomorphic cells/ and inflammatory infiltrate
#8327
middle Confidence
Subject:
Acral_myxoinflammatory_fibroblastic_sarcoma
(Tumor type)
→
exhibits
→
Object:
multinodular_configuration
(Organizational structure characteristics)
Original: Tumors#exhibited#a multinodular configuration with infiltrative margins/ myxoid and fibrotic zones/ pleomorphic cells/ and inflammatory infiltrate
#8325
middle Confidence
Subject:
Large_discohesive_cells
(Tumor cells)
→
contain
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Large discohesive cells#contained#abundant cytoplasm with eosinophilic inclusions/ eccentric vesicular nucleus/ and prominent nucleoli
#8324
middle Confidence
Subject:
Large_discohesive_cells
(Tumor cells)
→
contain
→
Object:
eccentric_vesicular_nucleus
(Cell morphology)
Original: Large discohesive cells#contained#abundant cytoplasm with eosinophilic inclusions/ eccentric vesicular nucleus/ and prominent nucleoli
#8323
middle Confidence
Subject:
Large_discohesive_cells
(Tumor cells)
→
contain
→
Object:
abundant_cytoplasm_with_eosinophilic_inclusions
(Cell morphology)
Original: Large discohesive cells#contained#abundant cytoplasm with eosinophilic inclusions/ eccentric vesicular nucleus/ and prominent nucleoli
#8322
middle Confidence
Subject:
Low_grade_epithelial_atypia_in_papillary_cell_groups
(Cell morphology)
→
accompanied_by
→
Object:
psammoma_bodies
(Organizational structure)
Original: Low grade epithelial atypia in papillary cell groups#accompanied#numerous psammoma bodies
#8321
middle Confidence
Subject:
Peritoneal_washings
(Biological samples)
→
contain
→
Object:
papillary_serous_cell_groups
(Cell Type)
Original: Peritoneal washings#contained#many papillary serous cell groups
#8256
middle Confidence
Subject:
Gross_and_histologic_findings
(Pathological examination)
→
support
→
Object:
diagnosis_of_uterine_leiomyoma
(Diagnosis conclusion)
Original: Gross and histologic findings#support#a diagnosis of uterine leiomyoma
#8254
middle Confidence
Subject:
Adenosarcoma
(Tumor type)
→
should_be_considered_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Adenosarcomas#should be considered#in the differential diagnosis when spindled cells are noted in a pap smear
#8166
middle Confidence
Subject:
cytologic_smears
(Cytology samples)
→
were_reviewed_with
→
Object:
histopathologic_sections
(Histopathology samples)
Original: Cytologic smears from equivocal cases#were reviewed with#histopathologic sections from patients who underwent biopsy or mastectomy
#8159
middle Confidence
Subject:
infiltrative_mass
(Tumor)
→
consisted_of
→
Object:
cuboidal_cells_arranged_in_irregular_follicles
(Tumor cell morphology)
Original: infiltrative mass#consisted of#cuboidal cells arranged in solid sheets and irregular follicles
#8158
middle Confidence
Subject:
infiltrative_mass
(Tumor)
→
consisted_of
→
Object:
cuboidal_cells_arranged_in_solid_sheets
(Tumor cell morphology)
Original: infiltrative mass#consisted of#cuboidal cells arranged in solid sheets and irregular follicles
#8155
middle Confidence
Subject:
ALK-negative_tumors
(Tumor classification)
→
are_associated_with
→
Object:
less_common_cytomorphologic_patterns
(Cell morphology)
Original: ALK-negative tumors#are associated with#less common cytomorphologic patterns
#8154
middle Confidence
Subject:
ALK-positive_group
(Molecular typing)
→
showed
→
Object:
cribriform_pattern_with_prominent_nucleoli
(Organizational structure phenotype)
Original: ALK-positive group#showed#cribriform pattern with prominent nucleoli
#8150
middle Confidence
Subject:
macronucleoli
(Cell morphology)
→
is_present_in
→
Object:
FNAs_from_TMC
(Sample Type)
Original: FNAs from TMC#showed#severe nuclear atypia and macronucleoli
#8149
middle Confidence
Subject:
nuclear_atypia
(Cell morphology)
→
is_present_in
→
Object:
FNAs_from_TMC
(Sample Type)
Original: FNAs from TMC#showed#severe nuclear atypia and macronucleoli
#8128
middle Confidence
Subject:
tumor
(Tumor tissue)
→
consists_of
→
Object:
atypical_spindle_cells_with_hyperchromatic_nuclei_and_nucleoli
(Tumor cell morphology)
Original: tumor#consists of#atypical spindle cells with hyperchromatic nuclei and nucleoli
#8127
middle Confidence
Subject:
Ultrasonographic_evaluation
(Medical imaging technology)
→
reveals
→
Object:
well-defined_mass_with_hypoechoic_nodules
(Imaging findings)
Original: Ultrasonographic evaluation#reveals#effusion and a well-defined mass with hypoechoic nodules
#8126
middle Confidence
Subject:
Ultrasonographic_evaluation
(Medical imaging technology)
→
reveals
→
Object:
effusion
(Imaging findings)
Original: Ultrasonographic evaluation#reveals#effusion and a well-defined mass with hypoechoic nodules
#8125
middle Confidence
Subject:
tumor
(Tumor tissue)
→
is_composed_of
→
Object:
epithelioid_cells_with_abundant_eosinophilic_cytoplasm_and_prominent_nucleoli
(Tumor cell morphology)
Original: tumor#is composed of#epithelioid cells with abundant eosinophilic cytoplasm and prominent nucleoli
#8087
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
round_to_oval_nuclei
(Cell morphology)
Original: Tumor cells#exhibit#epithelioid/ glomoid/ and spindle cells with eosinophilic and vacuolated cytoplasm and round to oval nuclei
#8086
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
vacuolated_cytoplasm
(Cell morphology)
Original: Tumor cells#exhibit#epithelioid/ glomoid/ and spindle cells with eosinophilic and vacuolated cytoplasm and round to oval nuclei
#8085
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
eosinophilic_cytoplasm
(Cell morphology)
Original: Tumor cells#exhibit#epithelioid/ glomoid/ and spindle cells with eosinophilic and vacuolated cytoplasm and round to oval nuclei
#8084
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
spindle_cells
(Cell morphology)
Original: Tumor cells#exhibit#epithelioid/ glomoid/ and spindle cells with eosinophilic and vacuolated cytoplasm and round to oval nuclei
#8083
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
glomoid_cells
(Cell morphology)
Original: Tumor cells#exhibit#epithelioid/ glomoid/ and spindle cells with eosinophilic and vacuolated cytoplasm and round to oval nuclei
#8082
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
epithelioid_cells
(Cell morphology)
Original: Tumor cells#exhibit#epithelioid/ glomoid/ and spindle cells with eosinophilic and vacuolated cytoplasm and round to oval nuclei
#8060
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
TP53
(Transcription Factors)
Original: Tumor cells#exhibited#positive immunoreactivity for AE1/AE3/ KRT19/ Pan-CK/ EMA/ P40/ P63/ CK34尾E12/ and P53
#8059
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
CK34E12
(Keratin)
Original: Tumor cells#exhibited#positive immunoreactivity for AE1/AE3/ KRT19/ Pan-CK/ EMA/ P40/ P63/ CK34尾E12/ and P53
#8058
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
P63
(Transcription Factors)
Original: Tumor cells#exhibited#positive immunoreactivity for AE1/AE3/ KRT19/ Pan-CK/ EMA/ P40/ P63/ CK34尾E12/ and P53
#8057
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
P40
(Transcription Factors)
Original: Tumor cells#exhibited#positive immunoreactivity for AE1/AE3/ KRT19/ Pan-CK/ EMA/ P40/ P63/ CK34尾E12/ and P53
#8056
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
EMA
(Epithelial membrane antigen)
Original: Tumor cells#exhibited#positive immunoreactivity for AE1/AE3/ KRT19/ Pan-CK/ EMA/ P40/ P63/ CK34尾E12/ and P53
#8055
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
Pan-CK
(Broad Spectrum Keratin)
Original: Tumor cells#exhibited#positive immunoreactivity for AE1/AE3/ KRT19/ Pan-CK/ EMA/ P40/ P63/ CK34尾E12/ and P53
#8054
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
KRT19
(Keratin)
Original: Tumor cells#exhibited#positive immunoreactivity for AE1/AE3/ KRT19/ Pan-CK/ EMA/ P40/ P63/ CK34尾E12/ and P53
#8053
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
AE1/AE3
(Cytokeratin complex)
Original: Tumor cells#exhibited#positive immunoreactivity for AE1/AE3/ KRT19/ Pan-CK/ EMA/ P40/ P63/ CK34尾E12/ and P53
#8044
middle Confidence
Subject:
nuclei_of_tumor_cells
(Nucleus)
→
are_vesicular_with
→
Object:
single_prominent_nucleolus
(Nucleolus)
Original: nuclei of tumor cells#are vesicular with#pale chromatin and single prominent nucleolus
#8043
middle Confidence
Subject:
nuclei_of_tumor_cells
(Nucleus)
→
are_vesicular_with
→
Object:
pale_chromatin
(Chromatin characteristics)
Original: nuclei of tumor cells#are vesicular with#pale chromatin and single prominent nucleolus
#8042
middle Confidence
Subject:
renal_EAML
(Tumor type)
→
presents
→
Object:
cherry-red_nucleoli_with_perinucleolar_halos
(Cell nucleolus characteristics)
Original: renal EAML#presents#tumor cells with abundant eosinophilic cytoplasm and cherry-red nucleoli with perinucleolar halos
#8041
middle Confidence
Subject:
renal_EAML
(Tumor type)
→
presents
→
Object:
tumor_cells_with_abundant_eosinophilic_cytoplasm
(Tumor cell morphology)
Original: renal EAML#presents#tumor cells with abundant eosinophilic cytoplasm and cherry-red nucleoli with perinucleolar halos
#8040
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
numerous_mitotic_figures
(Mitotic figures)
Original: tumor cells#are arranged in#organoid and trabecular patterns with extensive necrosis and numerous mitotic figures
#8039
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
associated_with
→
Object:
Necrosis
(Tissue necrosis)
Original: tumor cells#are arranged in#organoid and trabecular patterns with extensive necrosis and numerous mitotic figures
#8038
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_arranged_in
→
Object:
trabecular_pattern
(Organizational Structure)
Original: tumor cells#are arranged in#organoid and trabecular patterns with extensive necrosis and numerous mitotic figures
#8037
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_arranged_in
→
Object:
organoid_pattern
(Organizational Structure)
Original: tumor cells#are arranged in#organoid and trabecular patterns with extensive necrosis and numerous mitotic figures
#8036
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nucleolus)
Original: tumor cells#are characterized by#large cells with vesicular chromatin and prominent nucleoli
#8035
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_characterized_by
→
Object:
large_cells_with_vesicular_chromatin
(Nuclear characteristics)
Original: tumor cells#are characterized by#large cells with vesicular chromatin and prominent nucleoli
#8034
middle Confidence
Subject:
epithelioid_rhabdomyosarcoma
(Malignant tumors)
→
shows
→
Object:
proliferation_of_epithelioid_tumor_cells
(Tumor cell proliferation)
Original: Epithelioid rhabdomyosarcoma#shows#proliferation of epithelioid tumor cells with prominent nucleoli
#8033
middle Confidence
Subject:
carcinoma_cells
(Tumor cells)
→
associated_with
→
Object:
Necrosis
(Tissue necrosis)
Original: Carcinoma cells#frequently form#ductal structures with areas of necrosis
#8032
middle Confidence
Subject:
carcinoma_cells
(Tumor cells)
→
frequently_form
→
Object:
ductal_structures
(Organizational Structure)
Original: Carcinoma cells#frequently form#ductal structures with areas of necrosis
#8027
middle Confidence
Subject:
FNAC_of_lesion
(Diagnostic techniques)
→
revealed
→
Object:
vacuolated_cytoplasm
(Cytoplasmic structure)
Original: FNAC of the lesion#revealed#monomorphic plump cells with small single nucleolus and vacuolated cytoplasm
#8026
middle Confidence
Subject:
FNAC_of_lesion
(Diagnostic techniques)
→
revealed
→
Object:
monomorphic_plump_cells_with_small_single_nucleolus
(Cell Type)
Original: FNAC of the lesion#revealed#monomorphic plump cells with small single nucleolus and vacuolated cytoplasm
#7992
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
neuron-specific_enolase
(Molecular markers)
Original: neoplastic cells#are positive for#CEA/ epithelial membrane antigen/ Leu-7 (CD57)/ neuron-specific enolase
#7991
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
Leu-7
(Molecular markers)
Original: neoplastic cells#are positive for#CEA/ epithelial membrane antigen/ Leu-7 (CD57)/ neuron-specific enolase
#7990
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
epithelial_membrane_antigen
(Molecular markers)
Original: neoplastic cells#are positive for#CEA/ epithelial membrane antigen/ Leu-7 (CD57)/ neuron-specific enolase
#7989
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
CEA
(Molecular markers)
Original: neoplastic cells#are positive for#CEA/ epithelial membrane antigen/ Leu-7 (CD57)/ neuron-specific enolase
#7987
middle Confidence
Subject:
cytologic_findings
(Cytological characteristics)
→
are_described_in
→
Object:
juvenile_granulosa_cell_tumor
(disease)
Original: Study#describes#cytologic findings in adult and juvenile granulosa cell tumors
#7986
middle Confidence
Subject:
cytologic_findings
(Cytological characteristics)
→
are_described_in
→
Object:
adult_granulosa_cell_tumor
(disease)
Original: Study#describes#cytologic findings in adult and juvenile granulosa cell tumors
#7983
middle Confidence
Subject:
giant_cells_of_neoplasm
(Tumor cell type)
→
can_be_differentiated_from
→
Object:
epidermoid_carcinoma
(Tumor type)
Original: Giant cells of neoplasm#can be differentiated from#undifferentiated large cell carcinoma and epidermoid carcinoma
#7982
middle Confidence
Subject:
giant_cells_of_neoplasm
(Tumor cell type)
→
can_be_differentiated_from
→
Object:
undifferentiated_large_cell_carcinoma
(Tumor type)
Original: Giant cells of neoplasm#can be differentiated from#undifferentiated large cell carcinoma and epidermoid carcinoma
#7947
middle Confidence
Subject:
tumor
(Tumor)
→
consisted_entirely_of
→
Object:
clear_cells_with_prominent_nucleoli
(Tumor cells)
Original: tumor#consisted entirely of#clear cells with prominent nucleoli
#7946
middle Confidence
Subject:
tumors
(Tumor tissue)
→
showed
→
Object:
Leu-7
(Protein markers)
Original: Immunohistochemical positivity#was found in#11/13 for NSE/ 9/13 for cytokeratin/ 4/13 for Leu-7/ none for chromogranin A/ CEA/ or LCA
#7945
middle Confidence
Subject:
tumors
(Tumor tissue)
→
showed
→
Object:
cytokeratin
(Protein markers)
Original: Immunohistochemical positivity#was found in#11/13 for NSE/ 9/13 for cytokeratin/ 4/13 for Leu-7/ none for chromogranin A/ CEA/ or LCA
#7944
middle Confidence
Subject:
tumors
(Tumor tissue)
→
showed
→
Object:
NSE
(Protein markers)
Original: Immunohistochemical positivity#was found in#11/13 for NSE/ 9/13 for cytokeratin/ 4/13 for Leu-7/ none for chromogranin A/ CEA/ or LCA
#7905
middle Confidence
Subject:
NB_cells_with_large_and_vesicular_nuclei
(Neuroblastoma cells)
→
are_indicative_of
→
Object:
stem_cell-like_tumor_cells
(Cancer stem cells)
Original: NB cells with large and vesicular nuclei#are indicative of#stem cell-like tumor cells
#7890
middle Confidence
Subject:
tumor_sample
(Tissue samples)
→
diagnosed_as
→
Object:
IDA
(Pathological process)
Original: Tumor samples from 23 patients#were examined#cytologically for mucin-producing tumors
#7889
middle Confidence
Subject:
tumor_sample
(Tissue samples)
→
diagnosed_as
→
Object:
IPMC
(Tumor type)
Original: Tumor samples from 23 patients#were examined#cytologically for mucin-producing tumors
#7888
middle Confidence
Subject:
tumor_sample
(Tissue samples)
→
diagnosed_as
→
Object:
hyperplasia
(Pathological process)
Original: Tumor samples from 23 patients#were examined#cytologically for mucin-producing tumors
#7870
middle Confidence
Subject:
Cytopathology
(Cytopathology)
→
correctly_diagnoses
→
Object:
pilomatrixoma_cases
(Case)
Original: Cytopathology#correctly diagnoses#two cases of pilomatrixoma
#7869
middle Confidence
Subject:
aspirates
(Piercing fluid)
→
contain
→
Object:
basaloid_cells
(Cell Type)
Original: Aspirates#contain#basaloid cells with prominent nucleoli
#7868
middle Confidence
Subject:
immunohistochemical_study
(Immunohistochemistry studies)
→
reveals
→
Object:
differences_compared_to_apocrine_adenocarcinoma
(Histological differences)
Original: Immunohistochemical study#reveals#differences compared to apocrine adenocarcinoma
#7867
middle Confidence
Subject:
sAC_immunostaining
(Protein immunostaining)
→
is_related_to
→
Object:
nuclear_changes
(Nuclear changes)
Original: sAC immunostaining#is related to#cytological and nuclear changes in acral melanomas
#7866
middle Confidence
Subject:
sAC_immunostaining
(Protein immunostaining)
→
is_related_to
→
Object:
cytological_changes
(Cytological changes)
Original: sAC immunostaining#is related to#cytological and nuclear changes in acral melanomas
#7865
middle Confidence
Subject:
sAC_staining_patterns
(Molecular phenotype)
→
is_similar_to
→
Object:
acral_melanoma
(Tumor type)
Original: In vitro culture models#exhibit#sAC staining patterns similar to acral melanomas
#7864
middle Confidence
Subject:
diagnostic_consideration
(Diagnostic considerations)
→
includes
→
Object:
benign_glandular_lesion
(Benign lesions)
Original: Diagnostic considerations#include#metastatic adenocarcinomas/ nephrogenic adenomas/ and benign glandular lesions
#7863
middle Confidence
Subject:
diagnostic_consideration
(Diagnostic considerations)
→
includes
→
Object:
nephrogenic_adenoma
(Benign lesions)
Original: Diagnostic considerations#include#metastatic adenocarcinomas/ nephrogenic adenomas/ and benign glandular lesions
#7862
middle Confidence
Subject:
diagnostic_consideration
(Diagnostic considerations)
→
includes
→
Object:
metastatic_adenocarcinoma
(Tumor)
Original: Diagnostic considerations#include#metastatic adenocarcinomas/ nephrogenic adenomas/ and benign glandular lesions
#7859
middle Confidence
Subject:
clear_cell_adenocarcinomas
(Tumor)
→
may_present_in
→
Object:
urinary_cytology_specimens
(Test samples)
Original: Clear cell adenocarcinomas (CCAs)#may present in#urinary cytology specimens
#7838
middle Confidence
Subject:
Immunohistochemical analysis
(Immunohistochemistry)
→
was_negative_for
→
Object:
CD123
(Immune molecules)
Original: Immunohistochemical analysis#was negative for#CD123
#7837
middle Confidence
Subject:
Immunohistochemical analysis
(Immunohistochemistry)
→
was_positive_for
→
Object:
CD56
(Immune molecules)
Original: Immunohistochemical analysis#was positive for#CD4/ CD56
#7836
middle Confidence
Subject:
Immunohistochemical analysis
(Immunohistochemistry)
→
was_positive_for
→
Object:
CD4
(Immune molecules)
Original: Immunohistochemical analysis#was positive for#CD4/ CD56
#7787
middle Confidence
Subject:
histological_results
(Histological results)
→
revealed
→
Object:
benign_lesions
(Benign lesions)
Original: Histological results#revealed#intraepithelial or invasive neoplasia in 48% cases and benign lesions in 52% cases
#7786
middle Confidence
Subject:
histological_results
(Histological results)
→
revealed
→
Object:
invasive_neoplasia
(Tumor type)
Original: Histological results#revealed#intraepithelial or invasive neoplasia in 48% cases and benign lesions in 52% cases
#7785
middle Confidence
Subject:
histological_results
(Histological results)
→
revealed
→
Object:
intraepithelial_neoplasia
(Tumor type)
Original: Histological results#revealed#intraepithelial or invasive neoplasia in 48% cases and benign lesions in 52% cases
#7784
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
rhabdomyosarcoma
(Tumor type)
Original: Differential diagnoses#included#small round cell sarcomas like malignant lymphoma/ neuroblastoma/ Ewing's sarcoma/ and rhabdomyosarcoma
#7783
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
Ewing_sarcoma
(Tumor type)
Original: Differential diagnoses#included#small round cell sarcomas like malignant lymphoma/ neuroblastoma/ Ewing's sarcoma/ and rhabdomyosarcoma
#7782
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
neuroblastoma
(Tumor type)
Original: Differential diagnoses#included#small round cell sarcomas like malignant lymphoma/ neuroblastoma/ Ewing's sarcoma/ and rhabdomyosarcoma
#7781
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
malignant_lymphoma
(Tumor type)
Original: Differential diagnoses#included#small round cell sarcomas like malignant lymphoma/ neuroblastoma/ Ewing's sarcoma/ and rhabdomyosarcoma
#7780
middle Confidence
Subject:
nucleoli
(Nuclear structure)
→
associated_with
→
Object:
suspicion_of_coexisting_neoplasm
(Clinical phenotype)
Original: Nucleoli#are associated with#suspicion of a coexisting neoplasm
#7779
middle Confidence
Subject:
pre-operative_imaging
(Imaging tests)
→
demonstrates
→
Object:
non-enhancing_T2-hyperintense_multinodular_lesions
(Imaging phenotype)
Original: Pre-operative imaging#demonstrated#non-enhancing/ T2-hyperintense multinodular lesions in deep cortex and superficial white matter of frontal or temporal lobes
#7722
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
include
→
Object:
nuclear_atypia
(Nuclear atypia)
Original: Cytological criteria#included#cellularity/ cell pattern/ presence of necrosis/ nucleoli/ and nuclear atypia
#7721
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
include
→
Object:
nucleoli
(Nucleolus)
Original: Cytological criteria#included#cellularity/ cell pattern/ presence of necrosis/ nucleoli/ and nuclear atypia
#7720
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
include
→
Object:
presence_of_necrosis
(Necrotic characteristics)
Original: Cytological criteria#included#cellularity/ cell pattern/ presence of necrosis/ nucleoli/ and nuclear atypia
#7719
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
include
→
Object:
cell_pattern
(Cell arrangement characteristics)
Original: Cytological criteria#included#cellularity/ cell pattern/ presence of necrosis/ nucleoli/ and nuclear atypia
#7718
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
include
→
Object:
Cellularity
(Cell number characteristics)
Original: Cytological criteria#included#cellularity/ cell pattern/ presence of necrosis/ nucleoli/ and nuclear atypia
#7611
middle Confidence
Subject:
melanoma_in_situ
(disease)
→
lacks
→
Object:
subjacent_host_inflammatory_response
(Inflammatory response)
Original: melanoma in situ#lacks#lateral spread/ upward epidermal migration/ marked cytologic atypia/ finely granular "smoky" melanin pigment/ mitotic figures/ and a subjacent host inflammatory response
#7610
middle Confidence
Subject:
melanoma_in_situ
(disease)
→
lacks
→
Object:
mitotic_figures
(Cell division characteristics)
Original: melanoma in situ#lacks#lateral spread/ upward epidermal migration/ marked cytologic atypia/ finely granular "smoky" melanin pigment/ mitotic figures/ and a subjacent host inflammatory response
#7609
middle Confidence
Subject:
melanoma_in_situ
(disease)
→
lacks
→
Object:
finely_granular_smoky_melanin_pigment
(Pigment abnormalities)
Original: melanoma in situ#lacks#lateral spread/ upward epidermal migration/ marked cytologic atypia/ finely granular "smoky" melanin pigment/ mitotic figures/ and a subjacent host inflammatory response
#7608
middle Confidence
Subject:
melanoma_in_situ
(disease)
→
lacks
→
Object:
marked_cytologic_atypia
(Cytological abnormalities)
Original: melanoma in situ#lacks#lateral spread/ upward epidermal migration/ marked cytologic atypia/ finely granular "smoky" melanin pigment/ mitotic figures/ and a subjacent host inflammatory response
#7607
middle Confidence
Subject:
melanoma_in_situ
(disease)
→
lacks
→
Object:
upward_epidermal_migration
(Tumor Biological Characteristics)
Original: melanoma in situ#lacks#lateral spread/ upward epidermal migration/ marked cytologic atypia/ finely granular "smoky" melanin pigment/ mitotic figures/ and a subjacent host inflammatory response
#7606
middle Confidence
Subject:
melanoma_in_situ
(disease)
→
lacks
→
Object:
lateral_spread
(Tumor Biological Characteristics)
Original: melanoma in situ#lacks#lateral spread/ upward epidermal migration/ marked cytologic atypia/ finely granular "smoky" melanin pigment/ mitotic figures/ and a subjacent host inflammatory response
#7605
middle Confidence
Subject:
some_cells
(Tumor cells)
→
contain
→
Object:
intracytoplasmic_vacuoles
(Intracellular structure)
Original: Some cells#contain#intracytoplasmic vacuoles
#7604
middle Confidence
Subject:
nuclei
(Nucleus)
→
exhibit
→
Object:
prominent_nucleoli
(Nucleolus)
Original: Nuclei#exhibit#irregular contour with fine chromatin and prominent nucleoli
#7603
middle Confidence
Subject:
nuclei
(Nucleus)
→
exhibit
→
Object:
fine_chromatin
(Chromatin structure)
Original: Nuclei#exhibit#irregular contour with fine chromatin and prominent nucleoli
#7602
middle Confidence
Subject:
nuclei
(Nucleus)
→
exhibit
→
Object:
irregular_contour
(Nuclear structure)
Original: Nuclei#exhibit#irregular contour with fine chromatin and prominent nucleoli
#7601
middle Confidence
Subject:
intermediate-sized_cells
(Tumor cells)
→
densely_infiltrate
→
Object:
BPDCN
(disease)
Original: Morphological examination#shows#dense infiltration by intermediate-sized cells resembling blasts
#7600
middle Confidence
Subject:
BPDCN
(disease)
→
shows
→
Object:
immunophenotypic_features
(Immunophenotypic characteristics)
Original: BPDCN#is identified in#cerebrospinal fluid with cytomorphological and immunophenotypic features
#7599
middle Confidence
Subject:
BPDCN
(disease)
→
shows
→
Object:
cytomorphological_features
(Cell morphology)
Original: BPDCN#is identified in#cerebrospinal fluid with cytomorphological and immunophenotypic features
#7598
middle Confidence
Subject:
Nevomelanocytes
(Pigment cells)
→
exhibit
→
Object:
prominent_nucleoli
(Nucleolus)
Original: Nevomelanocytes#exhibit#nuclear enlargement/ pleomorphism/ hyperchromatism/ and prominent nucleoli
#7597
middle Confidence
Subject:
Nevomelanocytes
(Pigment cells)
→
exhibit
→
Object:
hyperchromatism
(Abnormal nuclear chromatin)
Original: Nevomelanocytes#exhibit#nuclear enlargement/ pleomorphism/ hyperchromatism/ and prominent nucleoli
#7596
middle Confidence
Subject:
Nevomelanocytes
(Pigment cells)
→
exhibit
→
Object:
Pleomorphism
(Cell polymorphism)
Original: Nevomelanocytes#exhibit#nuclear enlargement/ pleomorphism/ hyperchromatism/ and prominent nucleoli
#7595
middle Confidence
Subject:
Nevomelanocytes
(Pigment cells)
→
exhibit
→
Object:
nuclear_enlargement
(Nuclear abnormalities)
Original: Nevomelanocytes#exhibit#nuclear enlargement/ pleomorphism/ hyperchromatism/ and prominent nucleoli
#7594
middle Confidence
Subject:
pigmented_lesions
(Tissue lesions)
→
are_categorized_by
→
Object:
nuclear_atypicality
(Nuclear abnormalities)
Original: Pigmented lesions#are categorized by#type of nevus and nuclear atypicality
#7593
middle Confidence
Subject:
pigmented_lesions
(Tissue lesions)
→
are_categorized_by
→
Object:
type_of_nevus
(Organization Type)
Original: Pigmented lesions#are categorized by#type of nevus and nuclear atypicality
#7592
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
are_characteristic_of
→
Object:
low-grade_mucoepidermoid_carcinoma
(disease)
Original: Cytologic features#are characteristic of#low-grade mucoepidermoid carcinoma
#7591
middle Confidence
Subject:
polygonal_squamoid_cells
(Tumor cells)
→
forms_clusters_with
→
Object:
distinct_nucleoli
(Nuclear structure)
Original: FNAB#shows#clusters of polygonal squamoid cells with distinct nucleoli
#7557
middle Confidence
Subject:
cytologic_diagnosis
(Diagnostic Process)
→
diagnoses
→
Object:
Non-Hodgkin's_lymphoma
(disease)
Original: cytologic diagnosis of high-grade non-Hodgkin's (NHL)#was offered and confirmed by#histopathology
#7556
middle Confidence
Subject:
cytologic_diagnosis
(Diagnostic Process)
→
confirms
→
Object:
histopathology
(Diagnostic Methods)
Original: cytologic diagnosis of high-grade non-Hodgkin's (NHL)#was offered and confirmed by#histopathology
#7555
middle Confidence
Subject:
thyroid_cells
(Thyroid cells)
→
associated_with
→
Object:
medullary_carcinoma
(Tumor type)
Original: fine needle aspiration cytology#reviewed#medullary carcinomas of thyroid
#7554
middle Confidence
Subject:
large_cells
(Large cell tumor)
→
associated_with
→
Object:
non-Hodgkin's_lymphoma
(Tumor type)
Original: endometrial currettings#showed#malignant non-Hodgkin's lymphoma/ diffuse/ large cell type
#7553
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
expressed
→
Object:
CD3
(T cell markers)
Original: neoplastic cells#expressed#T-cell marker CD3
#7552
middle Confidence
Subject:
submandibular_lymph_node_biopsy
(Tissue samples)
→
revealed_no_evidence_of
→
Object:
neoplastic_invasion
(Tumor invasion)
Original: submandibular lymph node biopsy#revealed no evidence of#neoplastic invasion
#7551
middle Confidence
Subject:
cell_size
(Cytological characteristics)
→
is_statistically_significant_in
→
Object:
CLC
(Tumor type)
Original: cellularity and cell size#were statistically significant in comparison to#CLC
#7550
middle Confidence
Subject:
Cellularity
(Cytological characteristics)
→
is_statistically_significant_in
→
Object:
CLC
(Tumor type)
Original: cellularity and cell size#were statistically significant in comparison to#CLC
#7549
middle Confidence
Subject:
punch_biopsy
(Organization inspection)
→
shows
→
Object:
nodular_large_cell_lymphocytic_infiltrate
(Histological characteristics)
Original: punch biopsy#showed#diffuse and nodular large cell lymphocytic infiltrate with prominent eosinophilic nucleoli
#7548
middle Confidence
Subject:
punch_biopsy
(Organization inspection)
→
shows
→
Object:
diffuse_large_cell_lymphocytic_infiltrate
(Histological characteristics)
Original: punch biopsy#showed#diffuse and nodular large cell lymphocytic infiltrate with prominent eosinophilic nucleoli
#7531
middle Confidence
Subject:
cytologic_features
(Cell morphology)
→
were_found
→
Object:
helpful_in_typing_cases
(Diagnostic value)
Original: Cytologic features#were found#helpful in typing cases
#7530
middle Confidence
Subject:
Sorry, I have no idea what this means.
(organ)
→
showed
→
Object:
marked_sinusoidal_infiltration
(Histopathology)
Original: Liver and spleen#showed#marked sinusoidal infiltration
#7529
middle Confidence
Subject:
liver
(organ)
→
showed
→
Object:
marked_sinusoidal_infiltration
(Histopathology)
Original: Liver and spleen#showed#marked sinusoidal infiltration
#7528
middle Confidence
Subject:
clear_cell_adenomas
(Tumor tissue)
→
showed
→
Object:
large_lipid_vacuoles
(Cellular substructure)
Original: Clear cell adenomas#showed#large lipid vacuoles
#7527
middle Confidence
Subject:
diagnosis
(diagnosis)
→
is_based_on
→
Object:
bland_cytology
(Cytological characteristics)
Original: Diagnosis#is based on#preservation of nodular configuration and bland cytology
#7526
middle Confidence
Subject:
diagnosis
(diagnosis)
→
is_based_on
→
Object:
preservation_of_nodular_configuration
(Tissue morphology)
Original: Diagnosis#is based on#preservation of nodular configuration and bland cytology
#7518
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Histological examination)
→
showed
→
Object:
low_columnar_cells
(Cell Type)
Original: Fine needle aspiration biopsy#showed#cellular smears composed of cuboidal to low columnar cells
#7517
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Histological examination)
→
showed
→
Object:
cuboidal_cells
(Cell Type)
Original: Fine needle aspiration biopsy#showed#cellular smears composed of cuboidal to low columnar cells
#7488
middle Confidence
Subject:
adenoid_cystic_carcinoma
(Tumor type)
→
feature
→
Object:
small_nucleoli
(Nuclear structure)
Original: Features of adenoid cystic carcinoma#were#nuclear hyperchromasia and small nucleoli
#7487
middle Confidence
Subject:
adenoid_cystic_carcinoma
(Tumor type)
→
feature
→
Object:
nuclear_hyperchromasia
(Nuclear characteristics)
Original: Features of adenoid cystic carcinoma#were#nuclear hyperchromasia and small nucleoli
#7486
middle Confidence
Subject:
B_cells
(Cell Type)
→
show_monoclonal_expansion_confirmed_by
→
Object:
IgH_rearrangement_band
(Molecular markers)
Original: Monoclonal expansion of B cells#was confirmed by#IgH rearrangement band via Southern blot
#7485
middle Confidence
Subject:
B-cell_population_(CD20_positive)
(Cell Type)
→
has
→
Object:
CD20_positive
(Protein expression)
Original: Immunophenotypic analysis#revealed#a B-cell population (CD20 positive) with kappa-light-chain restriction
#7484
middle Confidence
Subject:
B-cell_population_(CD20_positive)
(Cell Type)
→
shows
→
Object:
kappa-light-chain_restriction
(Molecular markers)
Original: Immunophenotypic analysis#revealed#a B-cell population (CD20 positive) with kappa-light-chain restriction
#7474
middle Confidence
Subject:
Tissue_from_ASPS
(Tissue samples)
→
was_compared_using
→
Object:
electron_microscopy
(Electron microscopy)
Original: Tissue from ASPS#was compared using#light microscopy histology/ FNA cytology/ electron microscopy
#7473
middle Confidence
Subject:
Tissue_from_ASPS
(Tissue samples)
→
was_compared_using
→
Object:
FNA_cytology
(Cytological techniques)
Original: Tissue from ASPS#was compared using#light microscopy histology/ FNA cytology/ electron microscopy
#7472
middle Confidence
Subject:
Tissue_from_ASPS
(Tissue samples)
→
was_compared_using
→
Object:
light_microscopy_histology
(Histological techniques)
Original: Tissue from ASPS#was compared using#light microscopy histology/ FNA cytology/ electron microscopy
#7471
middle Confidence
Subject:
Fine_needle_aspiration
(Cytological detection technology)
→
correlates_with
→
Object:
ultrastructural_cytologic_features
(Ultrastructural cytological features)
Original: Fine needle aspiration#correlates with#ultrastructural cytologic features
#7439
middle Confidence
Subject:
needle_aspirations
(Clinical operation)
→
were_investigated_in
→
Object:
patients_with_thyroid_lesions
(patient)
Original: Needle aspirations#were investigated in#265 patients with thyroid lesions
#7438
middle Confidence
Subject:
special_staining
(Special dyeing)
→
facilitates
→
Object:
diagnosis_of_malignancy
(Disease diagnosis)
Original: Morphology/ immunohistochemistry/ and special staining#facilitate#diagnosis of malignancy
#7437
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
facilitates
→
Object:
diagnosis_of_malignancy
(Disease diagnosis)
Original: Morphology/ immunohistochemistry/ and special staining#facilitate#diagnosis of malignancy
#7436
middle Confidence
Subject:
morphology
(Morphological detection)
→
facilitates
→
Object:
diagnosis_of_malignancy
(Disease diagnosis)
Original: Morphology/ immunohistochemistry/ and special staining#facilitate#diagnosis of malignancy
#7426
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Detection Technology)
→
assessed_for
→
Object:
absence_of_cytologic_feature
(Cell morphology)
Original: Fine-needle aspiration biopsies#assessed for#the presence or absence of cytologic features
#7425
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Detection Technology)
→
assessed_for
→
Object:
presence_of_cytologic_feature
(Cell morphology)
Original: Fine-needle aspiration biopsies#assessed for#the presence or absence of cytologic features
#7323
middle Confidence
Subject:
S100
(protein)
→
helps_differentiate_from
→
Object:
Other_lesions
(Pathological entity)
Original: The immunohistochemical profile (S100 positive/ HMB-45 negative/ cytokeratin negative)#may help#differentiate it from other lesions
#7319
middle Confidence
Subject:
HPV-HNSCC
(Tumor type)
→
shows
→
Object:
well-developed_lymphoepithelial_features
(Histological characteristics)
Original: 22 cases of HPV-HNSCC#were identified with#well-developed lymphoepithelial features
#7312
middle Confidence
Subject:
Muscle_biopsy_specimens
(Tissue samples)
→
show
→
Object:
proliferation_of_small_round_cells
(Cell proliferation phenotype)
Original: Muscle biopsy specimens#show#proliferation of small round cells infiltrating striated muscle
#7310
middle Confidence
Subject:
cytomorphological_features
(Cell morphology)
→
were_compared_between
→
Object:
biopsied_samples
(Sample Type)
Original: Cytomorphological features#were compared between#ASC-H and biopsied samples
#7309
middle Confidence
Subject:
cytomorphological_features
(Cell morphology)
→
were_compared_between
→
Object:
ASC-H
(Pathological changes)
Original: Cytomorphological features#were compared between#ASC-H and biopsied samples
#7306
middle Confidence
Subject:
development_of_cytoplasmic_organelles
(Organelle development)
→
was_poorer_in
→
Object:
adenocarcinoma
(Tumor type)
Original: Development of cytoplasmic organelles#was poorer in#AAH than adenocarcinoma
#7305
middle Confidence
Subject:
development_of_cytoplasmic_organelles
(Organelle development)
→
was_poorer_in
→
Object:
AAH
(Pathological changes)
Original: Development of cytoplasmic organelles#was poorer in#AAH than adenocarcinoma
#7304
middle Confidence
Subject:
ultrastructure_of_AAH
(Cell ultrastructure)
→
was_compared_with
→
Object:
ultrastructure_of_adenocarcinoma
(Cell ultrastructure)
Original: Ultrastructure of AAH#was compared with#adenocarcinoma
#7282
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
shows
→
Object:
focal_staining_for_desmin
(Protein expression phenotype)
Original: neoplastic cells#show#focal staining for desmin
#7281
middle Confidence
Subject:
MSA
(Myosin)
→
shows_focal_staining
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#show#focal staining for MSA
#7280
middle Confidence
Subject:
alpha_SMA
(Actin)
→
shows_focal_staining
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#show#focal staining for alpha-SMA
#7278
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
high_nuclear_cytoplasmic_ratio
(Cell morphology)
Original: tumor cells#show#high nuclear/cytoplasmic ratio
#7277
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
resemble
→
Object:
rhabdomyoblastic_tumor_cells
(Tumor cells)
Original: tumor cells#resemble#rhabdomyoblastic tumor cells
#7276
middle Confidence
Subject:
chromogranin_A
(Secretory granule protein)
→
shows_positivity
→
Object:
cells
(cell)
Original: chromogranin A#shows#focal positivity
#7275
middle Confidence
Subject:
synaptophysin
(Synaptic vesicle protein)
→
shows_positivity
→
Object:
cells
(cell)
Original: synaptophysin#shows#focal positivity
#7274
middle Confidence
Subject:
neuron_specific_enolase
(Enzyme Protein)
→
shows_positivity
→
Object:
cells
(cell)
Original: neuron specific enolase#shows#focal positivity
#7273
middle Confidence
Subject:
MIC2(CD99)
(Cell membrane proteins)
→
shows_positivity
→
Object:
cells
(cell)
Original: MIC2 (CD99)#shows#positivity
#7272
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic techniques)
→
revealed
→
Object:
uniform_round_cell_proliferation
(Cytological characteristics)
Original: Fine needle aspiration cytology#revealed#uniform round cell proliferation
#7237
middle Confidence
Subject:
fine-needle_aspiration
(Check operation)
→
demonstrated
→
Object:
hypercells_with_discohesive_clusters
(Cytological characteristics)
Original: fine-needle aspiration#demonstrated#hypercells with discohesive clusters
#7235
middle Confidence
Subject:
tumors
(Tumor diseases)
→
showed
→
Object:
nests_of_spindle_cells
(Histological characteristics)
Original: Tumors#showed#sheets and nests of round to spindle cells
#7234
middle Confidence
Subject:
tumors
(Tumor diseases)
→
showed
→
Object:
sheets_of_round_cells
(Histological characteristics)
Original: Tumors#showed#sheets and nests of round to spindle cells
#7206
middle Confidence
Subject:
morphologic_features
(Morphological characteristics)
→
were_described_previously_in
→
Object:
paraganglioma-like_melanocytic_tumors
(Tumor type)
Original: morphologic features#were described previously in#primary dermal melanomas and paraganglioma-like melanocytic tumors
#7205
middle Confidence
Subject:
morphologic_features
(Morphological characteristics)
→
were_described_previously_in
→
Object:
primary_dermal_melanomas
(Tumor type)
Original: morphologic features#were described previously in#primary dermal melanomas and paraganglioma-like melanocytic tumors
#7204
middle Confidence
Subject:
array-comparative_genomic_hybridization
(Molecular detection technology)
→
displayed
→
Object:
whole_chromosome_7_gain
(Genomic variation)
Original: array-comparative genomic hybridization#displayed#whole chromosome 7 gain in 2 cases
#7203
middle Confidence
Subject:
cytopathologic_smears
(Cytology samples)
→
were_examined_in
→
Object:
adrenal_cortex_disorders
(Disease phenotype)
Original: cytopathologic smears and/or imprints#were examined in#human adrenal cortex and its disorders
#7202
middle Confidence
Subject:
cytopathologic_smears
(Cytology samples)
→
were_examined_in
→
Object:
human_adrenal_cortex
(Organ tissue)
Original: cytopathologic smears and/or imprints#were examined in#human adrenal cortex and its disorders
#7163
middle Confidence
Subject:
coexpression_of_markers
(Molecular markers)
→
aids_in
→
Object:
diagnosis_of_bronchial_biopsy
(diagnosis)
Original: Papillary pattern and coexpression of markers#aid in#diagnosis of bronchial biopsy
#7162
middle Confidence
Subject:
Papillary_pattern
(Histological characteristics)
→
aids_in
→
Object:
diagnosis_of_bronchial_biopsy
(diagnosis)
Original: Papillary pattern and coexpression of markers#aid in#diagnosis of bronchial biopsy
#7158
middle Confidence
Subject:
crystal-storing_histiocytes
(Histiocytes)
→
are_associated_with
→
Object:
lymphomas_of_mucosa-associated_lymphoid_tissue
(Tumor type)
Original: crystal-storing histiocytes#are associated with#lymphomas of mucosa-associated lymphoid tissue
#7156
middle Confidence
Subject:
Distinguishing_features
(Diagnostic features)
→
include
→
Object:
frequent_nucleoli
(Nuclear morphology)
Original: Distinguishing features#include#crowded glands/ nuclear enlargement/ and frequent nucleoli
#7155
middle Confidence
Subject:
Distinguishing_features
(Diagnostic features)
→
include
→
Object:
nuclear_enlargement
(Nuclear morphology)
Original: Distinguishing features#include#crowded glands/ nuclear enlargement/ and frequent nucleoli
#7154
middle Confidence
Subject:
Distinguishing_features
(Diagnostic features)
→
include
→
Object:
crowded_glands
(Organizational Structure)
Original: Distinguishing features#include#crowded glands/ nuclear enlargement/ and frequent nucleoli
#7144
middle Confidence
Subject:
alpha-1_antichemotrypsin_staining
(Molecular marker detection)
→
was_positive_in
→
Object:
tumor_samples
(Tumor samples)
Original: staining for vimentin and alpha-1 antichemotrypsin#was positive in#tumor samples
#7143
middle Confidence
Subject:
vimentin_staining
(Molecular marker detection)
→
was_positive_in
→
Object:
tumor_samples
(Tumor samples)
Original: staining for vimentin and alpha-1 antichemotrypsin#was positive in#tumor samples
#7141
middle Confidence
Subject:
metastatic_disease
(Disease phenotype)
→
is_diagnosed_in
→
Object:
Sorry, I have no idea what this means.
(organ)
Original: Metastatic disease#is diagnosed in#lung/ bone/ upper extremities/ pleura/ and spleen
#7140
middle Confidence
Subject:
metastatic_disease
(Disease phenotype)
→
is_diagnosed_in
→
Object:
pleura
(Organizational Structure)
Original: Metastatic disease#is diagnosed in#lung/ bone/ upper extremities/ pleura/ and spleen
#7139
middle Confidence
Subject:
metastatic_disease
(Disease phenotype)
→
is_diagnosed_in
→
Object:
upper_extremity
(Anatomical location)
Original: Metastatic disease#is diagnosed in#lung/ bone/ upper extremities/ pleura/ and spleen
#7138
middle Confidence
Subject:
metastatic_disease
(Disease phenotype)
→
is_diagnosed_in
→
Object:
bone
(organ)
Original: Metastatic disease#is diagnosed in#lung/ bone/ upper extremities/ pleura/ and spleen
#7137
middle Confidence
Subject:
metastatic_disease
(Disease phenotype)
→
is_diagnosed_in
→
Object:
lung
(organ)
Original: Metastatic disease#is diagnosed in#lung/ bone/ upper extremities/ pleura/ and spleen
#7134
middle Confidence
Subject:
average_nuclear_size_of_fibroblasts
(Nuclear morphology)
→
was_compared_between
→
Object:
benign_cases
(Benign cases)
Original: average nuclear size of fibroblasts#was compared between#PDAC and benign cases
#7133
middle Confidence
Subject:
average_nuclear_size_of_fibroblasts
(Nuclear morphology)
→
was_compared_between
→
Object:
PDAC_cases
(Disease Cases)
Original: average nuclear size of fibroblasts#was compared between#PDAC and benign cases
#7121
middle Confidence
Subject:
focus_of_atypical_single-cell_layer_lined_acini
(Pathological structure)
→
is_evaluated_by
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Focus of atypical single-cell layer lined acini#is evaluated by#3 minimal diagnostic criteria for cancer: infiltrative pattern/ nuclear enlargement and hyperchromasia/ and prominent nucleoli
#7120
middle Confidence
Subject:
focus_of_atypical_single-cell_layer_lined_acini
(Pathological structure)
→
is_evaluated_by
→
Object:
hyperchromasia
(Cell morphology)
Original: Focus of atypical single-cell layer lined acini#is evaluated by#3 minimal diagnostic criteria for cancer: infiltrative pattern/ nuclear enlargement and hyperchromasia/ and prominent nucleoli
#7119
middle Confidence
Subject:
focus_of_atypical_single-cell_layer_lined_acini
(Pathological structure)
→
is_evaluated_by
→
Object:
nuclear_enlargement
(Cell morphology)
Original: Focus of atypical single-cell layer lined acini#is evaluated by#3 minimal diagnostic criteria for cancer: infiltrative pattern/ nuclear enlargement and hyperchromasia/ and prominent nucleoli
#7118
middle Confidence
Subject:
focus_of_atypical_single-cell_layer_lined_acini
(Pathological structure)
→
is_evaluated_by
→
Object:
infiltrative_pattern
(Histological characteristics)
Original: Focus of atypical single-cell layer lined acini#is evaluated by#3 minimal diagnostic criteria for cancer: infiltrative pattern/ nuclear enlargement and hyperchromasia/ and prominent nucleoli
#7110
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
have
→
Object:
prominent_nucleoli_and_eosinophilic_cytoplasm
(Cellular substructure)
Original: Tumor cells#have#prominent nucleoli and eosinophilic cytoplasm
#7109
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
have
→
Object:
nuclear_enlargement_and_contour_irregularity
(Nuclear abnormalities)
Original: Tumor cells#have#nuclear enlargement and contour irregularity
#7108
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
cytological_atypia
(Cytological abnormalities)
Original: Tumor cells#exhibit#cytological atypia
#7078
middle Confidence
Subject:
papillary_tumor_cells
(Tumor cell subtype)
→
could_not_be_distinguished_in
→
Object:
effusion_specimens_unless_papillae_present
(Cytological diagnosis conditions)
Original: Cells from clear cell and papillary tumors#could not be distinguished in#effusion specimens unless papillae were present
#7077
middle Confidence
Subject:
clear_cell_tumor_cells
(Tumor cell subtype)
→
could_not_be_distinguished_in
→
Object:
effusion_specimens_unless_papillae_present
(Cytological diagnosis conditions)
Original: Cells from clear cell and papillary tumors#could not be distinguished in#effusion specimens unless papillae were present
#7072
middle Confidence
Subject:
tumors
(Tumor tissue)
→
show
→
Object:
interlacing_bundles_of_atypical_spindle_cells
(Cell morphological characteristics)
Original: tumors#show#interlacing bundles of atypical spindle cells
#7070
middle Confidence
Subject:
urine_cytology
(Urine cytology)
→
reveals
→
Object:
crowded_3-dimensional_clusters
(Cell morphology)
Original: urine cytology#reveals#crowded 3-dimensional clusters
#7069
middle Confidence
Subject:
cytological_preparations
(Cytological preparation)
→
display
→
Object:
large_polygonal_cells_with_prominent_nucleoli
(Cell morphology)
Original: cytological preparations#display#large polygonal cells with prominent nucleoli
#7068
middle Confidence
Subject:
cases
(Case)
→
have
→
Object:
cytomorphologic_features_of_large_cells_with_vesicular_nuclei
(Cell morphology)
Original: cases#have#cytomorphologic features of large cells with vesicular nuclei
#7055
middle Confidence
Subject:
tumors
(Tumor)
→
are_composed_of
→
Object:
small_central_eosinophilic_nucleoli
(Nucleolar morphology)
Original: Tumors#were composed of#slender spindle cells with eosinophilic cytoplasm/ fusiform/ tapering/ wavy nuclei/ vesicular nuclei/ and small central eosinophilic nucleoli
#7054
middle Confidence
Subject:
tumors
(Tumor)
→
are_composed_of
→
Object:
vesicular_nuclei
(Nuclear morphology)
Original: Tumors#were composed of#slender spindle cells with eosinophilic cytoplasm/ fusiform/ tapering/ wavy nuclei/ vesicular nuclei/ and small central eosinophilic nucleoli
#7053
middle Confidence
Subject:
tumors
(Tumor)
→
are_composed_of
→
Object:
wavy_nuclei
(Nuclear morphology)
Original: Tumors#were composed of#slender spindle cells with eosinophilic cytoplasm/ fusiform/ tapering/ wavy nuclei/ vesicular nuclei/ and small central eosinophilic nucleoli
#7052
middle Confidence
Subject:
tumors
(Tumor)
→
are_composed_of
→
Object:
tapering_nuclei
(Nuclear morphology)
Original: Tumors#were composed of#slender spindle cells with eosinophilic cytoplasm/ fusiform/ tapering/ wavy nuclei/ vesicular nuclei/ and small central eosinophilic nucleoli
#7051
middle Confidence
Subject:
tumors
(Tumor)
→
are_composed_of
→
Object:
fusiform_nuclei
(Nuclear morphology)
Original: Tumors#were composed of#slender spindle cells with eosinophilic cytoplasm/ fusiform/ tapering/ wavy nuclei/ vesicular nuclei/ and small central eosinophilic nucleoli
#7050
middle Confidence
Subject:
tumors
(Tumor)
→
are_composed_of
→
Object:
slender_spindle_cells_with_eosinophilic_cytoplasm
(Tumor cell morphology)
Original: Tumors#were composed of#slender spindle cells with eosinophilic cytoplasm/ fusiform/ tapering/ wavy nuclei/ vesicular nuclei/ and small central eosinophilic nucleoli
#7049
middle Confidence
Subject:
smears
(Cytology specimens)
→
showed
→
Object:
scanty_cytoplasm
(Cytoplasmic morphology)
Original: Smears#showed#discrete round to oval tumor cells with mild pleomorphism/ coarse chromatin/ inconspicuous nucleoli/ and scanty cytoplasm
#7048
middle Confidence
Subject:
smears
(Cytology specimens)
→
showed
→
Object:
inconspicuous_nucleoli
(Nucleolar morphology)
Original: Smears#showed#discrete round to oval tumor cells with mild pleomorphism/ coarse chromatin/ inconspicuous nucleoli/ and scanty cytoplasm
#7047
middle Confidence
Subject:
smears
(Cytology specimens)
→
showed
→
Object:
coarse_chromatin
(Chromatin morphology)
Original: Smears#showed#discrete round to oval tumor cells with mild pleomorphism/ coarse chromatin/ inconspicuous nucleoli/ and scanty cytoplasm
#7046
middle Confidence
Subject:
smears
(Cytology specimens)
→
showed
→
Object:
discrete_round_to_oval_tumor_cells_with_mild_pleomorphism
(Tumor cell morphology)
Original: Smears#showed#discrete round to oval tumor cells with mild pleomorphism/ coarse chromatin/ inconspicuous nucleoli/ and scanty cytoplasm
#7045
middle Confidence
Subject:
cells_lining_spaces_in_yolk_sac_tumor
(Tumor cells)
→
lacked
→
Object:
typical_prominent_nucleoli_of_seminoma_cells
(Nucleolar morphology)
Original: Cells lining spaces in yolk sac tumor#lacked#typical prominent nucleoli of seminoma cells
#7044
middle Confidence
Subject:
cells_lining_spaces_in_seminoma
(Tumor cells)
→
retained
→
Object:
typical_features_of_seminoma_cells
(Cell morphology)
Original: Cells lining spaces in seminoma#retained#typical features of seminoma cells
#7043
middle Confidence
Subject:
multiple_prominent_nucleoli
(Nucleolar morphology)
→
are_identified_as
→
Object:
important_features
(Diagnostic features)
Original: Large round nuclei with dispersed chromatin and multiple prominent nucleoli#were identified as#important features
#7042
middle Confidence
Subject:
dispersed_chromatin
(Chromatin morphology)
→
are_identified_as
→
Object:
important_features
(Diagnostic features)
Original: Large round nuclei with dispersed chromatin and multiple prominent nucleoli#were identified as#important features
#7041
middle Confidence
Subject:
large_round_nuclei
(Nuclear morphology)
→
are_identified_as
→
Object:
important_features
(Diagnostic features)
Original: Large round nuclei with dispersed chromatin and multiple prominent nucleoli#were identified as#important features
#7040
middle Confidence
Subject:
uninuclear_tumor_cells_with_high_nuclear-cytoplasmic_ratio
(Tumor cell morphology)
→
is_observed_in
→
Object:
Cellular_specimens
(Cytology specimens)
Original: Cellular specimens#consisted of#uninuclear tumor cells with high nuclear-cytoplasmic ratios
#7031
middle Confidence
Subject:
Lesion excision
(Surgical Procedure)
→
showed
→
Object:
features of cylindroma
(Disease phenotype)
Original: Lesion excision#showed#features of cylindroma
#7029
middle Confidence
Subject:
Cytology
(Cytology)
→
revealed
→
Object:
clusters of small round to oval cells with hyperchromatic nuclei
(Cell morphology)
Original: Cytology#revealed#clusters of small round to oval cells with hyperchromatic nuclei
#6959
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
pancreatoblastoma
(disease)
Original: Differential diagnosis#includes#chronic pancreatitis/ ductal adenocarcinoma/ solid pseudopapillary tumor/ acinar cell carcinoma/ and pancreatoblastoma
#6958
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
acinar_cell_carcinoma
(disease)
Original: Differential diagnosis#includes#chronic pancreatitis/ ductal adenocarcinoma/ solid pseudopapillary tumor/ acinar cell carcinoma/ and pancreatoblastoma
#6957
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
solid_pseudopapillary_tumor
(disease)
Original: Differential diagnosis#includes#chronic pancreatitis/ ductal adenocarcinoma/ solid pseudopapillary tumor/ acinar cell carcinoma/ and pancreatoblastoma
#6956
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
ductal_adenocarcinoma
(disease)
Original: Differential diagnosis#includes#chronic pancreatitis/ ductal adenocarcinoma/ solid pseudopapillary tumor/ acinar cell carcinoma/ and pancreatoblastoma
#6955
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
chronic_pancreatitis
(disease)
Original: Differential diagnosis#includes#chronic pancreatitis/ ductal adenocarcinoma/ solid pseudopapillary tumor/ acinar cell carcinoma/ and pancreatoblastoma
#6909
middle Confidence
Subject:
main_differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
parasellar_meningiomas
(Tumor)
Original: main differential diagnoses#included#pineal gland tumors/ pituitary adenomas/ craniopharyngiomas/ pilocytic astrocytomas/ and parasellar meningiomas
#6908
middle Confidence
Subject:
main_differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
pilocytic_astrocytomas
(Tumor)
Original: main differential diagnoses#included#pineal gland tumors/ pituitary adenomas/ craniopharyngiomas/ pilocytic astrocytomas/ and parasellar meningiomas
#6907
middle Confidence
Subject:
main_differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
craniopharyngiomas
(Tumor)
Original: main differential diagnoses#included#pineal gland tumors/ pituitary adenomas/ craniopharyngiomas/ pilocytic astrocytomas/ and parasellar meningiomas
#6906
middle Confidence
Subject:
main_differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
pituitary_adenomas
(Tumor)
Original: main differential diagnoses#included#pineal gland tumors/ pituitary adenomas/ craniopharyngiomas/ pilocytic astrocytomas/ and parasellar meningiomas
#6905
middle Confidence
Subject:
main_differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
pineal_gland_tumors
(Tumor)
Original: main differential diagnoses#included#pineal gland tumors/ pituitary adenomas/ craniopharyngiomas/ pilocytic astrocytomas/ and parasellar meningiomas
#6875
middle Confidence
Subject:
Histological_and_immunohistochemical_features
(Test results)
→
are_compatible_with
→
Object:
metanephric_adenoma
(Tumor type)
Original: Histological and immunohistochemical features#are compatible with#metanephric adenoma
#6874
middle Confidence
Subject:
Metanephric adenoma
(Tumor type)
→
must_be_distinguished_from
→
Object:
Nephroblastoma
(Tumor type)
Original: Metanephric adenoma#must be distinguished from#papillary renal cell carcinoma and nephroblastoma
#6873
middle Confidence
Subject:
Metanephric adenoma
(Tumor type)
→
must_be_distinguished_from
→
Object:
papillary_renal_cell_carcinoma
(Tumor type)
Original: Metanephric adenoma#must be distinguished from#papillary renal cell carcinoma and nephroblastoma
#6862
middle Confidence
Subject:
space-occupying_lesions
(Tissue phenotype)
→
should_be_included_in
→
Object:
differential_diagnosis_of_hepatic_neoplasm
(Clinical diagnostic criteria)
Original: Inflammatory conditions such as abscess/ cysts/ and tuberculoma#often present as#space-occupying lesions and should be included in the differential diagnosis of hepatic neoplasm
#6861
middle Confidence
Subject:
tuberculoma
(Inflammatory lesions)
→
presents_as
→
Object:
space-occupying_lesions
(Tissue phenotype)
Original: Inflammatory conditions such as abscess/ cysts/ and tuberculoma#often present as#space-occupying lesions and should be included in the differential diagnosis of hepatic neoplasm
#6860
middle Confidence
Subject:
cysts
(Inflammatory lesions)
→
presents_as
→
Object:
space-occupying_lesions
(Tissue phenotype)
Original: Inflammatory conditions such as abscess/ cysts/ and tuberculoma#often present as#space-occupying lesions and should be included in the differential diagnosis of hepatic neoplasm
#6859
middle Confidence
Subject:
Abscess
(Inflammatory lesions)
→
presents_as
→
Object:
space-occupying_lesions
(Tissue phenotype)
Original: Inflammatory conditions such as abscess/ cysts/ and tuberculoma#often present as#space-occupying lesions and should be included in the differential diagnosis of hepatic neoplasm
#6858
middle Confidence
Subject:
Cholangiocarcinoma
(Tumor type)
→
cannot_be_differentiated_from
→
Object:
metastatic_adenocarcinoma
(Tumor type)
Original: Cholangiocarcinoma#is characterized as#an adenocarcinoma and cannot be differentiated from metastatic adenocarcinoma on purely morphologic grounds
#6823
middle Confidence
Subject:
imaging
(Imaging tests)
→
demonstrated
→
Object:
multiple_masses_in_peritoneal_and_pelvic_cavities
(Imaging features)
Original: imaging#demonstrated#multiple masses in the peritoneal and pelvic cavities
#6822
middle Confidence
Subject:
pelvic_imaging
(Imaging tests)
→
showed
→
Object:
circumscribed_thickening_of_wall_of_small_intestinal_segment
(Imaging features)
Original: pelvic imaging#showed#a circumscribed thickening of the wall of a small intestinal segment
#6821
middle Confidence
Subject:
epidermis
(Organizational Structure)
→
shows
→
Object:
no_dysplasia
(Histological characteristics)
Original: epidermis#shows#no dysplasia
#6820
middle Confidence
Subject:
tumor
(Tumor tissue)
→
shows
→
Object:
no_glandular_differentiation
(Histological characteristics)
Original: tumors#show#no squamous or glandular differentiation
#6819
middle Confidence
Subject:
tumor
(Tumor tissue)
→
shows
→
Object:
no_squamous_differentiation
(Histological characteristics)
Original: tumors#show#no squamous or glandular differentiation
#6818
middle Confidence
Subject:
electron_microscopic_findings
(Electron microscope observation)
→
are_indicative_of
→
Object:
epithelial_differentiation
(Differentiation characteristics)
Original: Electron microscopic findings#are indicative of#epithelial differentiation
#6814
middle Confidence
Subject:
nuclei
(Nucleus)
→
were_characterized_by
→
Object:
small_and_monomorphic_shape_with_single_conspicuous_nucleolus
(Cell morphology)
Original: nuclei#were characterized by#small and monomorphic shape with a single conspicuous nucleolus
#6801
middle Confidence
Subject:
tumors
(Tumor)
→
retain
→
Object:
unique_cytomorphologic_features_in_CSF
(Cell morphology)
Original: tumors#retain#unique cytomorphologic features in CSF
#6800
middle Confidence
Subject:
case
(Case)
→
is
→
Object:
primary_pulmonary_malignant_meningioma
(Tumor diseases)
Original: case#is#primary pulmonary malignant meningioma
#6799
middle Confidence
Subject:
cases
(Case)
→
are
→
Object:
clinically_benign
(Disease phenotype)
Original: cases#are#histologically and clinically benign
#6798
middle Confidence
Subject:
cases
(Case)
→
are
→
Object:
histologically_benign
(Disease phenotype)
Original: cases#are#histologically and clinically benign
#6797
middle Confidence
Subject:
cells
(Tumor cells)
→
exhibit
→
Object:
three_mitoses_per_high_power_field
(Cell proliferation characteristics)
Original: Cells#exhibited#irregular vesicular nuclei/ conspicuous nucleolus/ and three mitoses per high power field
#6796
middle Confidence
Subject:
medium_to_large_cells
(Tumor cells)
→
proliferate
→
Object:
primary_cutaneous_diffuse_large_B-cell_lymphoma
(Tumor diseases)
Original: Histological study#showed#lymphocytic infiltration and diffuse proliferation of medium to large cells
#6795
middle Confidence
Subject:
lymphocytes
(Immune cells)
→
infiltrate
→
Object:
primary_cutaneous_diffuse_large_B-cell_lymphoma
(Tumor diseases)
Original: Histological study#showed#lymphocytic infiltration and diffuse proliferation of medium to large cells
#6783
middle Confidence
Subject:
nuclear_features_such_as_nucleoli_size
(Nuclear characteristics)
→
are_more_valuable_than
→
Object:
cytoplasmic_features
(Cytoplasmic characteristics)
Original: Nuclear features such as chromatin pattern and nucleoli size#are more valuable than#cytoplasmic features for distinguishing between two conditions
#6782
middle Confidence
Subject:
nuclear_features_such_as_chromatin_pattern
(Nuclear characteristics)
→
are_more_valuable_than
→
Object:
cytoplasmic_features
(Cytoplasmic characteristics)
Original: Nuclear features such as chromatin pattern and nucleoli size#are more valuable than#cytoplasmic features for distinguishing between two conditions
#6781
middle Confidence
Subject:
clear_cell_adenocarcinoma
(Tumor diseases)
→
is_characterized_by
→
Object:
macronucleolus
(Nucleolus)
Original: Clear cell adenocarcinoma#is characterized by#sheet-like cell arrangement/ polycrystal shape/ round nuclei/ granular chromatin/ and macronucleolus
#6780
middle Confidence
Subject:
clear_cell_adenocarcinoma
(Tumor diseases)
→
is_characterized_by
→
Object:
granular_chromatin
(Chromatin)
Original: Clear cell adenocarcinoma#is characterized by#sheet-like cell arrangement/ polycrystal shape/ round nuclei/ granular chromatin/ and macronucleolus
#6779
middle Confidence
Subject:
clear_cell_adenocarcinoma
(Tumor diseases)
→
is_characterized_by
→
Object:
round_nuclei
(Nucleus)
Original: Clear cell adenocarcinoma#is characterized by#sheet-like cell arrangement/ polycrystal shape/ round nuclei/ granular chromatin/ and macronucleolus
#6778
middle Confidence
Subject:
clear_cell_adenocarcinoma
(Tumor diseases)
→
is_characterized_by
→
Object:
polycrystal_shape
(Cell morphology)
Original: Clear cell adenocarcinoma#is characterized by#sheet-like cell arrangement/ polycrystal shape/ round nuclei/ granular chromatin/ and macronucleolus
#6777
middle Confidence
Subject:
clear_cell_adenocarcinoma
(Tumor diseases)
→
is_characterized_by
→
Object:
sheet-like_cell_arrangement
(Cell Arrangement)
Original: Clear cell adenocarcinoma#is characterized by#sheet-like cell arrangement/ polycrystal shape/ round nuclei/ granular chromatin/ and macronucleolus
#6776
middle Confidence
Subject:
papillary_cystadenocarcinomas_of_salivary_gland
(Tumor diseases)
→
exhibit
→
Object:
wider_morphologic_spectrum_than_WHO_classification
(Disease phenotype)
Original: Papillary cystadenocarcinomas of salivary gland#exhibit#wider morphologic spectrum than WHO classification indicates
#6775
middle Confidence
Subject:
Differential_diagnosis_of_lesion
(Diagnostic Process)
→
includes
→
Object:
metastases
(disease)
Original: Differential diagnosis of lesion#includes#cystadenoma/ salivary duct carcinoma/ and metastases
#6774
middle Confidence
Subject:
Differential_diagnosis_of_lesion
(Diagnostic Process)
→
includes
→
Object:
salivary_duct_carcinoma
(disease)
Original: Differential diagnosis of lesion#includes#cystadenoma/ salivary duct carcinoma/ and metastases
#6773
middle Confidence
Subject:
Differential_diagnosis_of_lesion
(Diagnostic Process)
→
includes
→
Object:
Cystadenoma
(disease)
Original: Differential diagnosis of lesion#includes#cystadenoma/ salivary duct carcinoma/ and metastases
#6756
middle Confidence
Subject:
cytologic_diagnosis
(Diagnostic techniques)
→
is_made_by
→
Object:
key_features_identified_by_logistic_regression
(Diagnostic features)
Original: Cytologic diagnosis#is made by#key features identified by logistic regression analysis
#6755
middle Confidence
Subject:
kappa_statistics_analysis
(Molecular analysis technology)
→
showed
→
Object:
agreement_between_cytologic_and_histologic_diagnoses
(Diagnostic consistency)
Original: Analysis using Kappa statistics#showed#excellent agreement between cytologic and histologic diagnoses
#6746
middle Confidence
Subject:
microbiopsies
(Material collection technology)
→
display
→
Object:
fibrolamellar_pattern
(Pathological morphology)
Original: Microbiopsies#display#fibrolamellar pattern in four cases
#6745
middle Confidence
Subject:
clinicopathological_findings
(Pathological characteristics)
→
are_reviewed_in
→
Object:
fibrolamellar_hepatocellular_carcinoma
(Tumor diseases)
Original: Cytologic and clinicopathological findings#are reviewed in#six fibrolamellar hepatocellular carcinomas
#6744
middle Confidence
Subject:
cytologic_findings
(Cytological characteristics)
→
are_reviewed_in
→
Object:
fibrolamellar_hepatocellular_carcinoma
(Tumor diseases)
Original: Cytologic and clinicopathological findings#are reviewed in#six fibrolamellar hepatocellular carcinomas
#6743
middle Confidence
Subject:
Anti-HMNA_antiserum
(Antibody)
→
reacts_with
→
Object:
nucleoli_in_neoplastic_lymphoma_cells
(Organelles/Tumor Cells)
Original: Anti-HMNA antiserum#reacts with#nucleoli in neoplastic lymphoma cells
#6742
middle Confidence
Subject:
low-grade_mucinous_adenocarcinoma_of_endometrium
(Malignant tumors)
→
compared_with
→
Object:
immunohistochemical_features
(Molecular markers)
Original: Comparison#was made between#morphologic and immunohistochemical features of cervical microglandular hyperplasia and low-grade mucinous adenocarcinoma of the endometrium
#6741
middle Confidence
Subject:
Cervical_microglandular_hyperplasia
(Benign lesions)
→
compared_with
→
Object:
immunohistochemical_features
(Molecular markers)
Original: Comparison#was made between#morphologic and immunohistochemical features of cervical microglandular hyperplasia and low-grade mucinous adenocarcinoma of the endometrium
#6740
middle Confidence
Subject:
Cervical_microglandular_hyperplasia
(Benign lesions)
→
compared_with
→
Object:
low-grade_mucinous_adenocarcinoma_of_endometrium
(Malignant tumors)
Original: Comparison#was made between#morphologic and immunohistochemical features of cervical microglandular hyperplasia and low-grade mucinous adenocarcinoma of the endometrium
#6738
middle Confidence
Subject:
Imaging
(Diagnostic techniques)
→
revealed
→
Object:
perforated_jejunal_mass
(Tumor morphological characteristics)
Original: Imaging#revealed#a perforated jejunal mass with disseminated metastases
#6723
middle Confidence
Subject:
criteria
(Diagnostic criteria)
→
distinguishes
→
Object:
benign_pleural_effusion
(disease)
Original: Stepwise logistic regression analysis#evaluated#criteria to distinguish adenocarcinoma in pleural effusion from benign effusion
#6722
middle Confidence
Subject:
criteria
(Diagnostic criteria)
→
distinguishes
→
Object:
adenocarcinoma
(disease)
Original: Stepwise logistic regression analysis#evaluated#criteria to distinguish adenocarcinoma in pleural effusion from benign effusion
#6665
middle Confidence
Subject:
Silver_staining_of_NORs
(Staining detection technology)
→
measures
→
Object:
ribosomal_gene_activity
(Gene expression activity)
Original: Silver staining of NORs#measures#ribosomal gene activity
#6611
middle Confidence
Subject:
putative_markers
(Candidate markers)
→
lack
→
Object:
specificity_for_CSCs
(Cancer stem cell specificity)
Original: putative markers#lack#specificity for CSCs
#6603
middle Confidence
Subject:
PD-L1
(Receptor protein)
→
is_expressed_in
→
Object:
Hodgkinoid_histiocytosis_histiocytes
(Histiocytes)
Original: Hodgkinoid histiocytosis#expresses#CD30/ S100/ and PD-L1 proteins
#6602
middle Confidence
Subject:
S100
(protein)
→
is_expressed_in
→
Object:
Hodgkinoid_histiocytosis_histiocytes
(Histiocytes)
Original: Hodgkinoid histiocytosis#expresses#CD30/ S100/ and PD-L1 proteins
#6601
middle Confidence
Subject:
CD30
(Receptor protein)
→
is_expressed_in
→
Object:
Hodgkinoid_histiocytosis_histiocytes
(Histiocytes)
Original: Hodgkinoid histiocytosis#expresses#CD30/ S100/ and PD-L1 proteins
#6592
middle Confidence
Subject:
CDH1
(Protein coding genes)
→
may_play_a_role_in
→
Object:
development_of_plasmacytoid_pattern
(Disease phenotype)
Original: Somatic CDH1 alterations#may play a role in#development of "plasmacytoid" pattern in prostatic adenocarcinoma
#6447
middle Confidence
Subject:
AgNOR_quantification
(Cell morphology detection method)
→
is_more_sensitive_than
→
Object:
CD25_expression
(Immune activation markers)
Original: AgNOR quantification#is more sensitive than#thymidine incorporation and CD25 expression for T cell activation detection
#6446
middle Confidence
Subject:
AgNOR_quantification
(Cell morphology detection method)
→
is_more_sensitive_than
→
Object:
thymidine_incorporation
(Cell proliferation assay)
Original: AgNOR quantification#is more sensitive than#thymidine incorporation and CD25 expression for T cell activation detection
#6329
middle Confidence
Subject:
methods
(Technical methods)
→
used_for
→
Object:
identification_of_prostatic_stem_cells
(Stem cell identification)
Original: Methods#were provided#for identifying prostatic stem cells/ including nuclear morphology and CD133 expression
#6318
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contain
→
Object:
abundant_RER
(Rich in rough endoplasmic reticulum)
Original: Tumor cells#contain#few mitochondria with dilated cristae and abundant RER
#6317
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contain
→
Object:
few_mitochondria_with_dilated_cristae
(Mitochondrial abnormalities)
Original: Tumor cells#contain#few mitochondria with dilated cristae and abundant RER
#6316
middle Confidence
Subject:
Proliferative_activity
(Cell proliferation activity)
→
studied_with
→
Object:
electron_microscopy
(Electron microscopy)
Original: Proliferative activity in oral carcinomas#studied with#Ag-NOR and electron microscopy
#6315
middle Confidence
Subject:
Proliferative_activity
(Cell proliferation activity)
→
studied_with
→
Object:
Ag-NOR
(Nucleolus-related structures)
Original: Proliferative activity in oral carcinomas#studied with#Ag-NOR and electron microscopy
#6314
middle Confidence
Subject:
Cytogenetic_analysis
(Cytogenetic analysis)
→
has_been_carried_out_in
→
Object:
cancer
(Tumor)
Original: Cytogenetic analysis#has been carried out in#many types of cancer
#6269
middle Confidence
Subject:
AgNORs
(Silver staining marker for the nucleolar organizer region)
→
compared_in
→
Object:
breast_lesions_in_fine_needle_aspiration_smears
(Breast lesion cytology)
Original: silver binding nucleolar organizer regions (AgNORs)#were compared in#breast lesions in histological sections and fine needle aspiration smears
#6268
middle Confidence
Subject:
AgNORs
(Silver staining marker for the nucleolar organizer region)
→
compared_in
→
Object:
breast_lesions_in_histological_sections
(Breast lesion tissue sections)
Original: silver binding nucleolar organizer regions (AgNORs)#were compared in#breast lesions in histological sections and fine needle aspiration smears
#6265
middle Confidence
Subject:
nucleolar_organizers
(Nucleolar organizing region)
→
are_quantified_for
→
Object:
benign_lymphoid_infiltrates
(Benign lymphocytic infiltration)
Original: nucleolar organizers#are quantified for#lymphomas and benign lymphoid infiltrates
#6264
middle Confidence
Subject:
nucleolar_organizers
(Nucleolar organizing region)
→
are_quantified_for
→
Object:
lymphoma
(Lymphoma)
Original: nucleolar organizers#are quantified for#lymphomas and benign lymphoid infiltrates
#6262
middle Confidence
Subject:
Ag-NORs
(Silver-stained nucleolar-associated granules)
→
were_analyzed_in
→
Object:
medulloblastoma
(Medulloblastoma)
Original: Argyrophilic Nucleolar Organizer Regions (Ag-NORs)#were analyzed in#medulloblastoma and cerebellar internal granular layer
#6256
middle Confidence
Subject:
Argyrophilic_nucleolar_organizer_regions
(Ag-affinity nucleolar organizing region)
→
assess
→
Object:
neoplastic_liver_tissue
(Tumorous liver tissue)
Original: Argyrophilic nucleolar organizer regions and associated proteins#assess#normal/ cirrhotic/ and neoplastic liver tissue
#6255
middle Confidence
Subject:
Argyrophilic_nucleolar_organizer_regions
(Ag-affinity nucleolar organizing region)
→
assess
→
Object:
cirrhotic_liver_tissue
(Cirrhosis of the liver)
Original: Argyrophilic nucleolar organizer regions and associated proteins#assess#normal/ cirrhotic/ and neoplastic liver tissue
#6254
middle Confidence
Subject:
Argyrophilic_nucleolar_organizer_regions
(Ag-affinity nucleolar organizing region)
→
assess
→
Object:
normal_liver_tissue
(Normal liver tissue)
Original: Argyrophilic nucleolar organizer regions and associated proteins#assess#normal/ cirrhotic/ and neoplastic liver tissue
#6253
middle Confidence
Subject:
Ag-NORs
(Nucleolus-associated protein)
→
were_studied_in
→
Object:
lymph_nodes
(Lymph nodes)
Original: nucleolar organizer region-associated proteins (Ag-NORs)#were studied in#non-Hodgkin's lymphomas and lymph nodes
#6252
middle Confidence
Subject:
Ag-NORs
(Nucleolus-associated protein)
→
were_studied_in
→
Object:
non-Hodgkin's_lymphoma
(Non-Hodgkin's lymphoma)
Original: nucleolar organizer region-associated proteins (Ag-NORs)#were studied in#non-Hodgkin's lymphomas and lymph nodes
#6247
middle Confidence
Subject:
nucleolar_organizer_regions
(Nuclear structure)
→
are_identified_in
→
Object:
colonic_dysplasia
(Disease phenotype)
Original: nucleolar organizer regions#were identified in#colonic dysplasia
#6240
middle Confidence
Subject:
specimens_stained_for_single_immunoglobulin_light_chain
(Tissue specimens)
→
indicate
→
Object:
monoclonal_B-cell_lymphoid_proliferation
(B cell proliferation)
Original: specimens stained for a single immunoglobulin light chain#indicated#monoclonal B-cell lymphoid proliferation
#6219
middle Confidence
Subject:
AgNORs
(Silver-stained nucleolar organizing region)
→
assess
→
Object:
multiple_myeloma
(Multiple Myeloma)
Original: silver-stainable nucleolar organizer regions (AgNORs)#assess#reactive plasmacytosis (RP) and multiple myeloma (MM)
#6218
middle Confidence
Subject:
AgNORs
(Silver-stained nucleolar organizing region)
→
assess
→
Object:
reactive_plasmacytosis
(Reactive plasmacytosis)
Original: silver-stainable nucleolar organizer regions (AgNORs)#assess#reactive plasmacytosis (RP) and multiple myeloma (MM)
#6195
middle Confidence
Subject:
nucleolar_organizer_regions_expression
(Molecular expression)
→
is_evaluated_for
→
Object:
male_breast_lesions
(Disease phenotype)
Original: Cytological criteria and expression of nuclear organizer regions#are evaluated for#diagnosing male breast lesions
#6193
middle Confidence
Subject:
histological_features
(Histological characteristics)
→
are_investigated_in
→
Object:
foamy_gland_carcinoma
(disease)
Original: Histological features and incidence#are investigated in#foamy gland carcinoma
#6181
middle Confidence
Subject:
AgNOR_technique
(Histochemical analysis techniques)
→
is_applied_to
→
Object:
touch_imprints
(Print Samples)
Original: AgNOR technique#is applied to#tissue sections and touch imprints from NHL
#6180
middle Confidence
Subject:
AgNOR_technique
(Histochemical analysis techniques)
→
is_applied_to
→
Object:
tissue_sections
(Tissue samples)
Original: AgNOR technique#is applied to#tissue sections and touch imprints from NHL
#6179
middle Confidence
Subject:
rRNA_content
(Ribosomal RNA content)
→
correlates_with
→
Object:
Ag-NOR_parameters
(Nucleolar Organizing Region Parameters)
Original: rRNA content#correlates with#quantitative Ag-NOR parameters in cells
#6150
middle Confidence
Subject:
immunohistochemical_method
(Detection Methods)
→
detects
→
Object:
synaptophysin
(Protein markers)
Original: Immunohistochemical method#detects#TTF1/ CKpan/ CK20/ S-100/ Ki-67/ CD56/ chromogranin A/ synaptophysin in MCC cases
#6149
middle Confidence
Subject:
immunohistochemical_method
(Detection Methods)
→
detects
→
Object:
chromogranin_A
(Protein markers)
Original: Immunohistochemical method#detects#TTF1/ CKpan/ CK20/ S-100/ Ki-67/ CD56/ chromogranin A/ synaptophysin in MCC cases
#6148
middle Confidence
Subject:
immunohistochemical_method
(Detection Methods)
→
detects
→
Object:
CD56
(Protein markers)
Original: Immunohistochemical method#detects#TTF1/ CKpan/ CK20/ S-100/ Ki-67/ CD56/ chromogranin A/ synaptophysin in MCC cases
#6147
middle Confidence
Subject:
immunohistochemical_method
(Detection Methods)
→
detects
→
Object:
Ki-67
(Protein markers)
Original: Immunohistochemical method#detects#TTF1/ CKpan/ CK20/ S-100/ Ki-67/ CD56/ chromogranin A/ synaptophysin in MCC cases
#6146
middle Confidence
Subject:
immunohistochemical_method
(Detection Methods)
→
detects
→
Object:
S-100
(Protein markers)
Original: Immunohistochemical method#detects#TTF1/ CKpan/ CK20/ S-100/ Ki-67/ CD56/ chromogranin A/ synaptophysin in MCC cases
#6145
middle Confidence
Subject:
immunohistochemical_method
(Detection Methods)
→
detects
→
Object:
CK20
(Protein markers)
Original: Immunohistochemical method#detects#TTF1/ CKpan/ CK20/ S-100/ Ki-67/ CD56/ chromogranin A/ synaptophysin in MCC cases
#6144
middle Confidence
Subject:
immunohistochemical_method
(Detection Methods)
→
detects
→
Object:
CKpan
(Protein markers)
Original: Immunohistochemical method#detects#TTF1/ CKpan/ CK20/ S-100/ Ki-67/ CD56/ chromogranin A/ synaptophysin in MCC cases
#6143
middle Confidence
Subject:
immunohistochemical_method
(Detection Methods)
→
detects
→
Object:
TTF1
(Protein markers)
Original: Immunohistochemical method#detects#TTF1/ CKpan/ CK20/ S-100/ Ki-67/ CD56/ chromogranin A/ synaptophysin in MCC cases
#6142
middle Confidence
Subject:
Statistical_methods
(Statistical methods)
→
analyzes
→
Object:
diagnostic_value_of_NORs
(Molecular analysis indicators)
Original: Statistical methods#are analyzed for#diagnostic value of NORs in colorectal neoplasms
#6126
middle Confidence
Subject:
AgNOR_frequency
(Nucleolar organizer region-related frequencies)
→
was_analyzed_in
→
Object:
lymphoma_in_cats
(Feline Lymphoma)
Original: AgNOR frequency#was analyzed in#lymphoma in cats
#6096
middle Confidence
Subject:
AgNOR_staining
(Molecular detection methods)
→
has_clinical_value_in
→
Object:
serous_effusion
(Clinical samples)
Original: Study#explored#clinical value of AgNOR staining in serous effusion
#6090
middle Confidence
Subject:
Atrophic_cancer
(Tumor type)
→
is_associated_with
→
Object:
collagenous_micronodules
(Tissue microenvironment components)
Original: Atrophic cancer#is associated with#collagenous micronodules
#6083
middle Confidence
Subject:
argyrophilic_NORs
(Nucleolar organizing region)
→
were_studied_in
→
Object:
adenocarcinoma
(disease)
Original: Specimens#were studied for#argyrophilic NORs in gall bladder lesions
#6082
middle Confidence
Subject:
argyrophilic_NORs
(Nucleolar organizing region)
→
were_studied_in
→
Object:
dysplasia
(disease)
Original: Specimens#were studied for#argyrophilic NORs in gall bladder lesions
#6081
middle Confidence
Subject:
argyrophilic_NORs
(Nucleolar organizing region)
→
were_studied_in
→
Object:
chronic_cholecystitis
(disease)
Original: Specimens#were studied for#argyrophilic NORs in gall bladder lesions
#6062
middle Confidence
Subject:
Silver_staining_technique
(Dyeing technology)
→
studies
→
Object:
nucleolar_organizer_regions_in_nasopharyngeal_carcinoma
(Subcellular structure)
Original: Silver staining technique#studies#nucleolar organizer regions (Ag-NORs) in nasopharyngeal carcinoma
#6044
middle Confidence
Subject:
silver_stained_nucleolar_organizer_regions
(Nucleolar organizer region)
→
were_evaluated_in
→
Object:
dysplastic_epithelium
(Epithelial tissue)
Original: Silver-stained nucleolar organizer regions#were evaluated in#normal and atypical/dysplastic epithelium of the urinary bladder
#6043
middle Confidence
Subject:
silver_stained_nucleolar_organizer_regions
(Nucleolar organizer region)
→
were_evaluated_in
→
Object:
atypical_epithelium
(Epithelial tissue)
Original: Silver-stained nucleolar organizer regions#were evaluated in#normal and atypical/dysplastic epithelium of the urinary bladder
#6042
middle Confidence
Subject:
silver_stained_nucleolar_organizer_regions
(Nucleolar organizer region)
→
were_evaluated_in
→
Object:
normal_epithelium
(Epithelial tissue)
Original: Silver-stained nucleolar organizer regions#were evaluated in#normal and atypical/dysplastic epithelium of the urinary bladder
#6040
middle Confidence
Subject:
LPN
(Number of large nucleolar particles)
→
are_helpful_in
→
Object:
differentiating_malignancy
(Malignant/benign differentiation)
Original: Particle numbers/ area/ and LPN#are helpful in#differentiating malignancy
#6039
middle Confidence
Subject:
particle_area
(Particle area)
→
are_helpful_in
→
Object:
differentiating_malignancy
(Malignant/benign differentiation)
Original: Particle numbers/ area/ and LPN#are helpful in#differentiating malignancy
#6038
middle Confidence
Subject:
particle_number
(Number of particles)
→
are_helpful_in
→
Object:
differentiating_malignancy
(Malignant/benign differentiation)
Original: Particle numbers/ area/ and LPN#are helpful in#differentiating malignancy
#6037
middle Confidence
Subject:
cytomorphometric_examination
(Cytomorphometric examination)
→
reveals
→
Object:
mean_AgNOR_count_per_nucleus
(Average number of nucleoli with silver staining in the nucleus)
Original: Cytomorphometric examination#reveals#a nuclear/cytoplasmic ratio of 0.14 and mean AgNOR count per nucleus of 2.86
#6036
middle Confidence
Subject:
cytomorphometric_examination
(Cytomorphometric examination)
→
reveals
→
Object:
nuclear_cytoplasmic_ratio
(NCR)
Original: Cytomorphometric examination#reveals#a nuclear/cytoplasmic ratio of 0.14 and mean AgNOR count per nucleus of 2.86
#6035
middle Confidence
Subject:
AgNOR_count
(Nucleoli with silver staining in the nucleus)
→
stepwise_application_increases
→
Object:
specificity_of_cytologic_diagnosis
(Diagnostic Accuracy)
Original: Stepwise application of morphology/ DNA content/ and AgNOR counts#increases#specificity of cytologic diagnosis
#6034
middle Confidence
Subject:
DNA_content
(DNA content)
→
stepwise_application_increases
→
Object:
specificity_of_cytologic_diagnosis
(Diagnostic Accuracy)
Original: Stepwise application of morphology/ DNA content/ and AgNOR counts#increases#specificity of cytologic diagnosis
#6033
middle Confidence
Subject:
morphology
(Cell/tissue morphology)
→
stepwise_application_increases
→
Object:
specificity_of_cytologic_diagnosis
(Diagnostic Accuracy)
Original: Stepwise application of morphology/ DNA content/ and AgNOR counts#increases#specificity of cytologic diagnosis
#6032
middle Confidence
Subject:
NORs
(Nucleolar organizer region)
→
is_analyzed_in
→
Object:
basal_cell_carcinoma
(Tumor)
Original: Morphometric analysis of NORs#is conducted in#ameloblastoma and basal cell carcinoma
#6031
middle Confidence
Subject:
NORs
(Nucleolar organizer region)
→
is_analyzed_in
→
Object:
ameloblastoma
(Tumor)
Original: Morphometric analysis of NORs#is conducted in#ameloblastoma and basal cell carcinoma
#6030
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
are_examined_in
→
Object:
malignant_breast_tissue
(Malignant tissue)
Original: AgNORs#are examined in#benign and malignant breast tissues
#6029
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
are_examined_in
→
Object:
benign_breast_tissue
(Benign tissue)
Original: AgNORs#are examined in#benign and malignant breast tissues
#6028
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
are_located_in
→
Object:
astrocytic_tumor_nuclei
(Tumor cell nucleus)
Original: AgNORs#are located in#astrocytic tumor nuclei
#6027
middle Confidence
Subject:
ERBB2_immunostaining
(Protein immunostaining)
→
is_performed_in
→
Object:
carcinoma_breast_cases
(Disease phenotype)
Original: AgNOR counts and c-erb B-2 immunostaining#are performed in#carcinoma breast cases
#6026
middle Confidence
Subject:
AgNOR_counts
(Molecular detection technology)
→
are_performed_in
→
Object:
carcinoma_breast_cases
(Disease phenotype)
Original: AgNOR counts and c-erb B-2 immunostaining#are performed in#carcinoma breast cases
#6023
middle Confidence
Subject:
AgNOR_counts
(Molecular detection technology)
→
are_evaluated_in
→
Object:
breast_carcinoma_cases
(Disease phenotype)
Original: AgNOR counts#are evaluated in#carcinoma breast cases
#6022
middle Confidence
Subject:
AgNOR_counting
(Molecular detection technology)
→
is_used_for
→
Object:
proliferation_characteristics_of_CTVT
(Cellular Processes)
Original: AgNOR counting#is used for#determining proliferation characteristics of CTVT
#6021
middle Confidence
Subject:
AgNORs_associated_proteins
(Nucleolus-associated protein)
→
are_compared_with
→
Object:
Ki-67_immunostaining
(Proliferation detection index)
Original: Silver-stained proteins associated with AgNORs#are compared with#BrdU incorporation and Ki-67 immunostaining in tumors
#6020
middle Confidence
Subject:
AgNORs_associated_proteins
(Nucleolus-associated protein)
→
are_compared_with
→
Object:
BrdU_incorporation
(Proliferation detection index)
Original: Silver-stained proteins associated with AgNORs#are compared with#BrdU incorporation and Ki-67 immunostaining in tumors
#6019
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
are_localized_with
→
Object:
PCNA
(Proliferation-related proteins)
Original: Silver-stained nucleolar organizer regions (AgNORs)#are localized with#ER/ PR/ and PCNA in breast cancer cells
#6018
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
are_localized_with
→
Object:
PR
(Receptor protein)
Original: Silver-stained nucleolar organizer regions (AgNORs)#are localized with#ER/ PR/ and PCNA in breast cancer cells
#6017
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region)
→
are_localized_with
→
Object:
ER
(Receptor protein)
Original: Silver-stained nucleolar organizer regions (AgNORs)#are localized with#ER/ PR/ and PCNA in breast cancer cells
#6005
middle Confidence
Subject:
interphase_NORs
(Nucleolar organizer region (interphase))
→
were_modified_in
→
Object:
breast_carcinomas
(Breast cancer)
Original: interphase NORs#were modified in#atypical lesions and breast carcinomas
#6004
middle Confidence
Subject:
interphase_NORs
(Nucleolar organizer region (interphase))
→
were_modified_in
→
Object:
atypical_lesions
(Atypical lesions)
Original: interphase NORs#were modified in#atypical lesions and breast carcinomas
#5997
middle Confidence
Subject:
cellular_proliferating_activity
(Cell proliferation activity)
→
was_analyzed_in
→
Object:
breast_cancer
(Breast cancer)
Original: AgNOR method#was used to analyze#cellular proliferating activity in breast cancer
#5996
middle Confidence
Subject:
AgNOR_method
(Molecular detection technology)
→
was_used_to_analyze
→
Object:
cellular_proliferating_activity
(Cell proliferation activity)
Original: AgNOR method#was used to analyze#cellular proliferating activity in breast cancer
#5959
middle Confidence
Subject:
silver_colloid_technique
(Silver gel staining technique)
→
was_applied_to
→
Object:
small_cell_tumors_of_childhood
(Small cell tumors in children)
Original: Silver colloid technique for AgNORs#was applied to#small cell tumors of childhood
#5954
middle Confidence
Subject:
AgNOR_silver_colloid_technique
(Staining method)
→
is_used_to_assess
→
Object:
invasive_squamous_cell_carcinoma
(Tumor)
Original: AgNOR silver colloid technique#is used to assess#actinic keratosis/ in situ SCC/ and invasive SCC
#5953
middle Confidence
Subject:
AgNOR_silver_colloid_technique
(Staining method)
→
is_used_to_assess
→
Object:
in_situ_squamous_cell_carcinoma
(Tumor)
Original: AgNOR silver colloid technique#is used to assess#actinic keratosis/ in situ SCC/ and invasive SCC
#5952
middle Confidence
Subject:
AgNOR_silver_colloid_technique
(Staining method)
→
is_used_to_assess
→
Object:
actinic_keratosis
(Benign tumors)
Original: AgNOR silver colloid technique#is used to assess#actinic keratosis/ in situ SCC/ and invasive SCC
#5945
middle Confidence
Subject:
AgNOR_staining
(Staining method)
→
is_used_to_examine
→
Object:
squamous_cell_carcinoma
(Tumor)
Original: AgNOR staining#is used to examine#epithelial neoplasms like SEB/ BCC/ SK/ BD/ and SCC
#5944
middle Confidence
Subject:
AgNOR_staining
(Staining method)
→
is_used_to_examine
→
Object:
Bowen's_disease
(Tumor)
Original: AgNOR staining#is used to examine#epithelial neoplasms like SEB/ BCC/ SK/ BD/ and SCC
#5943
middle Confidence
Subject:
AgNOR_staining
(Staining method)
→
is_used_to_examine
→
Object:
solar_keratosis
(Benign tumors)
Original: AgNOR staining#is used to examine#epithelial neoplasms like SEB/ BCC/ SK/ BD/ and SCC
#5942
middle Confidence
Subject:
AgNOR_staining
(Staining method)
→
is_used_to_examine
→
Object:
basal_cell_carcinoma
(Tumor)
Original: AgNOR staining#is used to examine#epithelial neoplasms like SEB/ BCC/ SK/ BD/ and SCC
#5941
middle Confidence
Subject:
AgNOR_staining
(Staining method)
→
is_used_to_examine
→
Object:
seborrheic_keratosis
(Benign tumors)
Original: AgNOR staining#is used to examine#epithelial neoplasms like SEB/ BCC/ SK/ BD/ and SCC
#5940
middle Confidence
Subject:
NORs
(Nucleolar organizing region)
→
are_counted_in
→
Object:
renal_adenoma
(Tumor)
Original: NORs#are counted in#renal cell carcinomas/ renal oncocytomas/ and renal adenomas
#5939
middle Confidence
Subject:
NORs
(Nucleolar organizing region)
→
are_counted_in
→
Object:
renal_oncocytoma
(Tumor)
Original: NORs#are counted in#renal cell carcinomas/ renal oncocytomas/ and renal adenomas
#5938
middle Confidence
Subject:
NORs
(Nucleolar organizing region)
→
are_counted_in
→
Object:
renal_cell_carcinoma
(Tumor)
Original: NORs#are counted in#renal cell carcinomas/ renal oncocytomas/ and renal adenomas
#5910
middle Confidence
Subject:
AgNORs
(Nucleolar Organizing Region-associated Protein)
→
were_measured_in
→
Object:
giant_cell_tumor_of_bones
(disease)
Original: AgNOR technique#measured#NORs in giant cell tumors of bones
#5909
middle Confidence
Subject:
AgNORs
(Nucleolar Organizing Region-associated Protein)
→
were_quantitatively_analyzed_in
→
Object:
giant_cell_lesions_of_jaws
(disease)
Original: Quantitative analysis#was performed on#argyrophilic nuclear organizer regions in jaw lesions
#5870
middle Confidence
Subject:
BRCA1_antibody_staining
(Antibody testing)
→
was_found_in
→
Object:
papilloma_tissue
(organize)
Original: BRCA1 antibody staining#was found in#tumor and papilloma tissues
#5869
middle Confidence
Subject:
BRCA1_antibody_staining
(Antibody testing)
→
was_found_in
→
Object:
tumor_tissue
(organize)
Original: BRCA1 antibody staining#was found in#tumor and papilloma tissues
#5832
middle Confidence
Subject:
cutaneous_epithelioid_angiomatous_nodule
(Tumor)
→
differentiated_from
→
Object:
vascular_proliferation_with_epithelioid_cytology
(Vascular tumors)
Original: Differential diagnosis of cutaneous epithelioid angiomatous nodules#is discussed with#other vascular proliferations that exhibit epithelioid cytology
#5824
middle Confidence
Subject:
signet_ring_cell_feature
(Cell morphology)
→
is_considered_as
→
Object:
cytologic_change
(Cytological changes)
Original: Signet ring cell feature in lung adenocarcinoma#is no longer considered#a distinct subtype but a cytologic change
#5823
middle Confidence
Subject:
fibroadenoma
(Benign tumors)
→
involved_by
→
Object:
LCIS
(Lobular carcinoma in situ)
Original: Three of the 11 cases#had#fibroadenomas with extensive involvement by LCIS
#5821
middle Confidence
Subject:
effusion_cytology
(Diagnostic techniques)
→
may_be_important_in
→
Object:
initial_assessment_of_hepatocellular_carcinoma
(Diagnostic Process)
Original: Effusion cytology#may be important in#the initial assessment of hepatocellular carcinoma
#5820
middle Confidence
Subject:
Pathological_findings
(Pathological examination)
→
showed
→
Object:
nests_of_small_round_cells_with_fine_granular_chromatin
(Cell morphology)
Original: Pathological findings#showed#nests of small round cells with fine granular chromatin
#5819
middle Confidence
Subject:
colonoscopic_crush_cytology
(Diagnostic techniques)
→
is
→
Object:
method_to_evaluate_colonic_neoplasms
(Diagnostic Methods)
Original: colonoscopic crush cytology#is#a method to evaluate colonic neoplasms
#5818
middle Confidence
Subject:
dysplastic_nevus
(Skin lesions)
→
has
→
Object:
histologic_abnormalities
(Histopathological characteristics)
Original: dysplastic nevi#have#varying histologic abnormalities
#5817
middle Confidence
Subject:
virus-negative_Merkel_cell_carcinoma
(Disease subtype)
→
is_characterized_by
→
Object:
distinct_morphological_features
(Pathological characteristics)
Original: virus-positive and virus-negative Merkel cell carcinoma#are characterized by#distinct morphological and immunohistochemical features
#5816
middle Confidence
Subject:
virus-positive_Merkel_cell_carcinoma
(Disease subtype)
→
is_characterized_by
→
Object:
distinct_morphological_features
(Pathological characteristics)
Original: virus-positive and virus-negative Merkel cell carcinoma#are characterized by#distinct morphological and immunohistochemical features
#5815
middle Confidence
Subject:
cytokeratin_7
(Cytoskeletal proteins)
→
exhibits
→
Object:
frequent_positivity_in_virus-negative_cases
(Immunohistochemical characteristics)
Original: cytokeratin 7#exhibits#frequent positivity in virus-negative cases
#5814
middle Confidence
Subject:
thyroid_transcription_factor_1
(Transcription Factors)
→
exhibits
→
Object:
frequent_positivity_in_virus-negative_cases
(Immunohistochemical characteristics)
Original: thyroid transcription factor 1#exhibits#frequent positivity in virus-negative cases
#5806
middle Confidence
Subject:
poorly_differentiated_carcinoma_component
(Tumor subtype)
→
displays
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: poorly differentiated carcinoma component#displayed#prominent nucleoli
#5801
middle Confidence
Subject:
awareness_of_nevus_cells
(Diagnostic Cognition)
→
helps
→
Object:
correct_diagnosis
(Diagnosis conclusion)
Original: awareness of nevus cells in nodal parenchyma#helps#pathologists establish correct diagnosis
#5789
middle Confidence
Subject:
Grade_2_endometrial_endometrioid_adenocarcinoma_cases
(disease)
→
were_reviewed_to_confirm
→
Object:
presence_of_atypia
(Cellular atypia)
Original: Grade 2 endometrial endometrioid adenocarcinoma cases#were reviewed#to confirm grade/ percent solid growth/ and presence of atypia
#5788
middle Confidence
Subject:
Grade_2_endometrial_endometrioid_adenocarcinoma_cases
(disease)
→
were_reviewed_to_confirm
→
Object:
percent_solid_growth
(Organization ratio)
Original: Grade 2 endometrial endometrioid adenocarcinoma cases#were reviewed#to confirm grade/ percent solid growth/ and presence of atypia
#5787
middle Confidence
Subject:
Grade_2_endometrial_endometrioid_adenocarcinoma_cases
(disease)
→
were_reviewed_to_confirm
→
Object:
grade
(Disease classification)
Original: Grade 2 endometrial endometrioid adenocarcinoma cases#were reviewed#to confirm grade/ percent solid growth/ and presence of atypia
#5764
middle Confidence
Subject:
Hepatocellular carcinoma (HCC)
(Hepatocellular carcinoma)
→
presented_with
→
Object:
headaches of increasing frequency and severity
(symptom)
Original: A 69-year-old male with HCV and post-hepatitic cirrhosis#presented with#headaches of increasing frequency and severity
#5756
middle Confidence
Subject:
Cytology
(Detection Technology)
→
is_compared_with
→
Object:
histology
(Detection Technology)
Original: Cytology#is compared with#histology for cyst differentiation
#5737
middle Confidence
Subject:
MAMs
(Tumor type)
→
is_characterized_by
→
Object:
prominent_nucleoli
(Prominent nucleoli)
Original: MAMs#characterized by#abundant dyshesive pleomorphic malignant cells containing prominent nucleoli
#5736
middle Confidence
Subject:
MAMs
(Tumor type)
→
is_characterized_by
→
Object:
abundant_dyshesive_pleomorphic_malignant_cells
(Tumor cell phenotype)
Original: MAMs#characterized by#abundant dyshesive pleomorphic malignant cells containing prominent nucleoli
#5735
middle Confidence
Subject:
Glomangiosarcoma
(Tumor type)
→
is_characterized_by
→
Object:
mitotic_activity
(Mitosis active)
Original: Glomangiosarcoma#is characterized by#marked cellular pleomorphism/ nuclear atypia/ and mitotic activity
#5734
middle Confidence
Subject:
Glomangiosarcoma
(Tumor type)
→
is_characterized_by
→
Object:
nuclear_atypia
(Nuclear atypia)
Original: Glomangiosarcoma#is characterized by#marked cellular pleomorphism/ nuclear atypia/ and mitotic activity
#5733
middle Confidence
Subject:
Glomangiosarcoma
(Tumor type)
→
is_characterized_by
→
Object:
cellular_pleomorphism
(Cell polymorphism)
Original: Glomangiosarcoma#is characterized by#marked cellular pleomorphism/ nuclear atypia/ and mitotic activity
#5732
middle Confidence
Subject:
AgNOR_counts
(Nucleolar organizer region count)
→
were_done_in
→
Object:
benign_glands
(Benign glands)
Original: AgNOR counts#were done in#adenocarcinoma nuclei and benign glands
#5731
middle Confidence
Subject:
AgNOR_counts
(Nucleolar organizer region count)
→
were_done_in
→
Object:
adenocarcinoma_nuclei
(Tumor cell nucleus)
Original: AgNOR counts#were done in#adenocarcinoma nuclei and benign glands
#5717
middle Confidence
Subject:
AgNOR_quantification
(Nucleolar organizer region quantification)
→
performed_in
→
Object:
transitional_cell_carcinoma_cells
(Transitional cell carcinoma cell)
Original: Quantification of AgNORs#was carried out in#urinary exfoliative cells from benign urological diseases and transitional cell carcinomas
#5716
middle Confidence
Subject:
AgNOR_quantification
(Nucleolar organizer region quantification)
→
performed_in
→
Object:
benign_urological_disease_cells
(Benign urological disease cells)
Original: Quantification of AgNORs#was carried out in#urinary exfoliative cells from benign urological diseases and transitional cell carcinomas
#5715
middle Confidence
Subject:
AgNOR_quantification
(Nucleolar organizer region quantification)
→
performed_in
→
Object:
urinary_exfoliative_cells
(Urine exfoliated cells)
Original: Quantification of AgNORs#was carried out in#urinary exfoliative cells from benign urological diseases and transitional cell carcinomas
#5675
middle Confidence
Subject:
Testicular_tumor
(Tumor)
→
was_identified_as
→
Object:
metastatic_hepatocellular_carcinoma
(Tumor)
Original: Testicular tumor#was identified as#a metastatic hepatocellular carcinoma
#5658
middle Confidence
Subject:
tumors
(Tumor tissue)
→
are_recognized_as
→
Object:
incidental_finding_at_autopsy
(Clinical diagnosis phenomenon)
Original: Many of these tumors#are recognized as#an incidental finding at autopsy
#5641
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_negative_for
→
Object:
CEA
(Tumor marker protein)
Original: Neoplastic cells#were negative for#cytokeratin 20 and CEA
#5640
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_negative_for
→
Object:
cytokeratin_20
(Structural proteins)
Original: Neoplastic cells#were negative for#cytokeratin 20 and CEA
#5639
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
EMA
(Tumor marker protein)
Original: Neoplastic cells#were positive for#high-molecular-weight cytokeratin/ cytokeratin 7/ and EMA
#5638
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
cytokeratin_7
(Structural proteins)
Original: Neoplastic cells#were positive for#high-molecular-weight cytokeratin/ cytokeratin 7/ and EMA
#5637
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
high-molecular-weight_cytokeratin
(Structural proteins)
Original: Neoplastic cells#were positive for#high-molecular-weight cytokeratin/ cytokeratin 7/ and EMA
#5619
middle Confidence
Subject:
clinical_examination
(Clinical examination)
→
revealed
→
Object:
neck_mass_suggestive_of_thyroid_lesion
(Clinical findings)
Original: Clinical examination and imaging studies#revealed#a neck mass suggestive of a thyroid lesion
#5618
middle Confidence
Subject:
histologic_features
(Histological characteristics)
→
are_well_characterized_in
→
Object:
LGFMS
(Tumor type)
Original: The spectrum of histologic features#is well characterized in#LGFMS
#5612
middle Confidence
Subject:
Basaloid_cells
(Tumor cells)
→
showed
→
Object:
mildly_pleomorphic_nuclei
(Nuclear morphology)
Original: Basaloid cells#showed#mildly pleomorphic nuclei/ small nucleoli and occasional mitotic figures
#5583
middle Confidence
Subject:
Wrights_stain
(Dyeing technology)
→
results_in
→
Object:
diagnostic_error_as_malignant_blast
(Diagnostic Error)
Original: Quality of Wright's stain#resulted in#diagnostic error as malignant blast
#5568
middle Confidence
Subject:
All_cases
(Case)
→
exhibit
→
Object:
cytologic_atypia
(Abnormal cell phenotype)
Original: All cases#exhibit#cytologic atypia
#5560
middle Confidence
Subject:
76_year_old_woman
(patient)
→
presented_with
→
Object:
mass_in_left_frontal_scalp
(Lump)
Original: 76-year-old woman#presented with#a mass in the left frontal region of the scalp
#5553
middle Confidence
Subject:
Postirradiation_biopsies
(Pathological samples)
→
underestimated
→
Object:
prostatectomy_Gleason_grade
(Pathological grading)
Original: Postirradiation biopsies#underestimated#prostatectomy Gleason grade in 35% of cases
#5531
middle Confidence
Subject:
PTLGM
(disease)
→
is_difficult_to_distinguish_from
→
Object:
FA_of_cellular_type
(disease)
Original: PTLGM#is difficult to distinguish from#FA of the cellular type using fine needle aspiration cytology
#5520
middle Confidence
Subject:
Reed-Sternberg_cells
(Tumor cell type)
→
identified_in
→
Object:
appropriate_cellular_background
(Tissue Microenvironment)
Original: Reed-Sternberg cells#were identified in#an appropriate cellular background
#5514
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
obvious_nucleoli
(Nucleolus)
Original: Tumor cells#show#large atypical nuclei and obvious nucleoli
#5513
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
large_atypical_nuclei
(Nuclear morphology)
Original: Tumor cells#show#large atypical nuclei and obvious nucleoli
#5510
middle Confidence
Subject:
Atypical_hematologic_cells
(Abnormal blood cells)
→
show
→
Object:
variably_prominent_nucleoli
(Nucleolar morphology)
Original: Atypical hematologic cells#show#irregular nuclear contours/ increased nuclear-to-cytoplasmic ratios/ and variably prominent nucleoli
#5509
middle Confidence
Subject:
Atypical_hematologic_cells
(Abnormal blood cells)
→
show
→
Object:
increased_nuclear-to-cytoplasmic_ratios
(Nuclear-cytoplasmic ratio)
Original: Atypical hematologic cells#show#irregular nuclear contours/ increased nuclear-to-cytoplasmic ratios/ and variably prominent nucleoli
#5508
middle Confidence
Subject:
Atypical_hematologic_cells
(Abnormal blood cells)
→
show
→
Object:
irregular_nuclear_contours
(Nuclear structure)
Original: Atypical hematologic cells#show#irregular nuclear contours/ increased nuclear-to-cytoplasmic ratios/ and variably prominent nucleoli
#5507
middle Confidence
Subject:
Langhans' giant cells
(Multinucleated macrophages)
→
are_found_in
→
Object:
6-week_post-treatment_biopsy
(Tissue specimens)
Original: Langhans' giant cells#are found in#6-week post-treatment biopsy
#5496
middle Confidence
Subject:
cells
(cell)
→
show_positive_immunoreactivity_for
→
Object:
leukocyte_common_antigen
(Differentiation markers)
Original: cells#show#positive immunoreactivity for leukocyte common antigen
#5472
middle Confidence
Subject:
CT_thorax
(Imaging tests)
→
revealed
→
Object:
SVC_obstruction
(Disease phenotype)
Original: CT thorax#revealed#SVC obstruction
#5459
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
prominent_nucleoli
(Nuclear morphology)
Original: tumor#shows#large vesicular nuclei with prominent nucleoli
#5458
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
large_vesicular_nuclei
(Nuclear morphology)
Original: tumor#shows#large vesicular nuclei with prominent nucleoli
#5439
middle Confidence
Subject:
additional_diagnostic_method
(Diagnostic Methods)
→
differentiations
→
Object:
malignant_follicular_neoplasms
(Malignant tumors)
Original: AgNOR study in thyroid lesions#can be used as#additional diagnostic method to differentiate benign and malignant follicular neoplasms
#5438
middle Confidence
Subject:
additional_diagnostic_method
(Diagnostic Methods)
→
differentiations
→
Object:
benign_follicular_neoplasms
(Benign tumors)
Original: AgNOR study in thyroid lesions#can be used as#additional diagnostic method to differentiate benign and malignant follicular neoplasms
#5433
middle Confidence
Subject:
pancreatic_lesion
(Tumor)
→
was
→
Object:
well-circumscribed_golden-yellow_solid_mass
(Tumor morphology)
Original: pancreatic lesion#was#a well-circumscribed/ golden-yellow solid mass lobulated by septal fibrosis
#5416
middle Confidence
Subject:
Histological_criteria
(Histological criteria)
→
includes
→
Object:
increase_in_nucleoli_size
(Cell morphology)
Original: Histological criteria#includes#increase in nucleoli size
#5415
middle Confidence
Subject:
ASC-H_category
(Cytological typing)
→
lacks
→
Object:
nucleoli
(Cell morphology)
Original: ASC-H category#lacks#nucleoli
#5410
middle Confidence
Subject:
Plasma_cells
(Plasma cells)
→
showed
→
Object:
focal_staining_for_EMA
(Molecular marker expression)
Original: Cells#showed#diffuse positivity for CD138 and focal staining for EMA
#5409
middle Confidence
Subject:
Plasma_cells
(Plasma cells)
→
showed
→
Object:
diffuse_positivity_for_CD138
(Molecular marker expression)
Original: Cells#showed#diffuse positivity for CD138 and focal staining for EMA
#5374
middle Confidence
Subject:
FNAC
(Cytology)
→
is_useful_for
→
Object:
rapid_diagnosis
(Diagnostic Process)
Original: FNAC#may be useful for#rapid diagnosis and management of extranodal NHL of the tongue
#5370
middle Confidence
Subject:
adenoid_basal_carcinoma
(Tumor type)
→
shows
→
Object:
higher_nuclear_cytoplasmic_ratio_than_reactive_atypia
(Cytological characteristics)
Original: adenoid basal carcinoma#shows#higher nuclear/cytoplasmic ratio than reactive atypia
#5369
middle Confidence
Subject:
Mitochondria
(Organelles)
→
showed
→
Object:
marked_pleomorphism
(Cell morphology changes)
Original: Mitochondria#showed#marked pleomorphism
#5368
middle Confidence
Subject:
nucleoli
(Nuclear components)
→
are_increased_in_size
→
Object:
enlarged_nucleoli
(Nuclear components)
Original: Nucleoli#are#increased in size
#5367
middle Confidence
Subject:
smears
(Cytology specimens)
→
reveal
→
Object:
nuclear_moulding
(Nuclear characteristics)
Original: Smears#revealed#small round cells with scant cytoplasm and nuclear moulding
#5366
middle Confidence
Subject:
smears
(Cytology specimens)
→
reveal
→
Object:
small_round_cells_with_scant_cytoplasm
(Cell morphology)
Original: Smears#revealed#small round cells with scant cytoplasm and nuclear moulding
#5361
middle Confidence
Subject:
prominent_nucleoli
(Nucleolar characteristics)
→
are_associated_with
→
Object:
pancreatic_adenocarcinoma
(Tumor diseases)
Original: Prominent nucleoli#are associated with#pancreatic adenocarcinoma
#5360
middle Confidence
Subject:
nuclear_enlargement
(Nuclear morphology)
→
is_associated_with
→
Object:
pancreatic_adenocarcinoma
(Tumor diseases)
Original: Nuclear enlargement#is associated with#pancreatic adenocarcinoma
#5359
middle Confidence
Subject:
nuclear_crowding
(Nuclear morphology)
→
is_associated_with
→
Object:
pancreatic_adenocarcinoma
(Tumor diseases)
Original: Nuclear crowding#is associated with#pancreatic adenocarcinoma
#5300
middle Confidence
Subject:
neoplasm_mass
(Tumor)
→
was_diagnosed_as
→
Object:
adenocarcinoma_of_seminal_vesicles
(Tumor type)
Original: neoplasm (mass)#was diagnosed as#adenocarcinoma of the seminal vesicles
#5295
middle Confidence
Subject:
LCNEC
(Tumor type)
→
was_diagnosed_in
→
Object:
palliative_transurethral_resection_specimen
(Specimen type)
Original: LCNEC#was diagnosed in#palliative transurethral resection specimens
#5294
middle Confidence
Subject:
MRI
(Imaging tests)
→
shows
→
Object:
irregular_shaped_nodule_in_right_breast
(Disease phenotype)
Original: MRI#showed#gynecomastia of bilateral breasts and irregular-shaped nodule in right breast
#5293
middle Confidence
Subject:
MRI
(Imaging tests)
→
shows
→
Object:
gynecomastia
(Disease phenotype)
Original: MRI#showed#gynecomastia of bilateral breasts and irregular-shaped nodule in right breast
#5242
middle Confidence
Subject:
EBER1_expression
(Molecular markers)
→
is_demonstrated_in
→
Object:
Adenocarcinoma
(Tumor)
Original: EBER1 expression#is demonstrated in#poorly differentiated squamous cell carcinoma and adenocarcinomas
#5241
middle Confidence
Subject:
EBER1_expression
(Molecular markers)
→
is_demonstrated_in
→
Object:
Squamous_cell_carcinoma
(Tumor)
Original: EBER1 expression#is demonstrated in#poorly differentiated squamous cell carcinoma and adenocarcinomas
#5240
middle Confidence
Subject:
EBV_presence
(Virus infection status)
→
is_evaluated_in
→
Object:
Lung_cancer
(Tumor)
Original: EBV presence#is evaluated in#lung cancers of Japanese patients
#5239
middle Confidence
Subject:
diagnostic_difficulty
(Difficulty in diagnosis)
→
is_associated_with
→
Object:
Rare_tumors
(Tumor)
Original: Cytological features of rare tumors#highlight#difficulty in making a definitive intraoperative diagnosis
#5238
middle Confidence
Subject:
Cytological_features
(Cytological characteristics)
→
highlight
→
Object:
diagnostic_difficulty
(Difficulty in diagnosis)
Original: Cytological features of rare tumors#highlight#difficulty in making a definitive intraoperative diagnosis
#5211
middle Confidence
Subject:
rhabdoid_tumor_of_kidney
(Tumor)
→
is_confused_with
→
Object:
renal_neoplasms
(Tumor)
Original: Renal neoplasms#resulted in#confusion with rhabdoid tumor of kidney
#5210
middle Confidence
Subject:
renal_neoplasms
(Tumor)
→
resulted_in
→
Object:
confusion_with_rhabdoid_tumor_of_kidney
(Diagnostic Confusion)
Original: Renal neoplasms#resulted in#confusion with rhabdoid tumor of kidney
#5209
middle Confidence
Subject:
endobronchial_tumor
(Tumor)
→
is_composed_of
→
Object:
occasional_conspicuous_nucleoli
(Nucleolar morphology)
Original: Endobronchial tumor#was composed of#nests of ovoid cells with eosinophilic cytoplasm/ cytoplasmic vacuoles/ round to oval nuclei with speckled chromatin/ and occasional conspicuous nucleoli
#5208
middle Confidence
Subject:
endobronchial_tumor
(Tumor)
→
is_composed_of
→
Object:
round_to_oval_nuclei_with_speckled_chromatin
(Nuclear morphology)
Original: Endobronchial tumor#was composed of#nests of ovoid cells with eosinophilic cytoplasm/ cytoplasmic vacuoles/ round to oval nuclei with speckled chromatin/ and occasional conspicuous nucleoli
#5207
middle Confidence
Subject:
endobronchial_tumor
(Tumor)
→
is_composed_of
→
Object:
cytoplasmic_vacuoles
(Cell structure)
Original: Endobronchial tumor#was composed of#nests of ovoid cells with eosinophilic cytoplasm/ cytoplasmic vacuoles/ round to oval nuclei with speckled chromatin/ and occasional conspicuous nucleoli
#5206
middle Confidence
Subject:
endobronchial_tumor
(Tumor)
→
is_composed_of
→
Object:
nests_of_ovoid_cells_with_eosinophilic_cytoplasm
(Cell structure)
Original: Endobronchial tumor#was composed of#nests of ovoid cells with eosinophilic cytoplasm/ cytoplasmic vacuoles/ round to oval nuclei with speckled chromatin/ and occasional conspicuous nucleoli
#5205
middle Confidence
Subject:
small_distinct_nucleoli
(Nucleolar morphology)
→
is_included_in
→
Object:
cytomorphological_spectrum
(Cytological spectrum)
Original: Cytomorphological spectrum#included#oval to elongate nuclei with finely granular chromatin and small distinct nucleoli
#5204
middle Confidence
Subject:
finely_granular_chromatin
(Chromatin morphology)
→
is_included_in
→
Object:
cytomorphological_spectrum
(Cytological spectrum)
Original: Cytomorphological spectrum#included#oval to elongate nuclei with finely granular chromatin and small distinct nucleoli
#5203
middle Confidence
Subject:
oval_to_elongate_nuclei
(Nuclear morphology)
→
is_included_in
→
Object:
cytomorphological_spectrum
(Cytological spectrum)
Original: Cytomorphological spectrum#included#oval to elongate nuclei with finely granular chromatin and small distinct nucleoli
#5148
middle Confidence
Subject:
core_FH-associated_tumoral_morphologic_features
(Tumor morphological characteristics)
→
included
→
Object:
prominent_nucleoli
(Nuclear morphology)
Original: core "FH-associated" tumoral morphologic features#included#staghorn vasculature/ bizarre nuclei/ and prominent nucleoli
#5147
middle Confidence
Subject:
core_FH-associated_tumoral_morphologic_features
(Tumor morphological characteristics)
→
included
→
Object:
bizarre_nuclei
(Nuclear morphology)
Original: core "FH-associated" tumoral morphologic features#included#staghorn vasculature/ bizarre nuclei/ and prominent nucleoli
#5146
middle Confidence
Subject:
core_FH-associated_tumoral_morphologic_features
(Tumor morphological characteristics)
→
included
→
Object:
staghorn_vasculature
(Vascular morphology)
Original: core "FH-associated" tumoral morphologic features#included#staghorn vasculature/ bizarre nuclei/ and prominent nucleoli
#5145
middle Confidence
Subject:
differential_diagnostic_list
(Differential Diagnosis)
→
includes
→
Object:
spindle_cell_lesions
(Histopathological features)
Original: differential diagnostic list#includes#spindle cell lesions/ especially of fibroblastic-myofibroblastic nature
#5141
middle Confidence
Subject:
primary_pulmonary_meningiomas
(Tumor diseases)
→
may_present_as
→
Object:
high-grade_malignant_lesions
(Disease phenotype)
Original: primary pulmonary meningiomas#may present as#high-grade malignant lesions
#5140
middle Confidence
Subject:
cells
(Tumor cells)
→
exhibit
→
Object:
rhabdoid_features
(Cell morphology)
Original: cells#exhibit#rhabdoid features
#5139
middle Confidence
Subject:
right_upper_lobe_mass
(Tumor lesions)
→
showed
→
Object:
loss_of_architectural_pattern
(Abnormal tissue structure)
Original: right upper lobe mass#showed#features of atypical meningioma with loss of architectural pattern
#5138
middle Confidence
Subject:
right_upper_lobe_mass
(Tumor lesions)
→
showed
→
Object:
features_of_atypical_meningioma
(Tumor tissue characteristics)
Original: right upper lobe mass#showed#features of atypical meningioma with loss of architectural pattern
#5137
middle Confidence
Subject:
cells
(Tumor cells)
→
exhibit
→
Object:
conspicuous_nucleolus
(Cell morphology)
Original: Cells#exhibited#irregular vesicular nuclei/ conspicuous nucleolus/ and three mitoses per high power field
#5136
middle Confidence
Subject:
cells
(Tumor cells)
→
exhibit
→
Object:
irregular_vesicular_nuclei
(Cell morphology)
Original: Cells#exhibited#irregular vesicular nuclei/ conspicuous nucleolus/ and three mitoses per high power field
#5110
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic techniques)
→
showed
→
Object:
malignant_cells_with_elongated_nuclei
(Cell phenotype)
Original: Fine needle aspiration cytology#showed#malignant cells with round-oval to focally elongated nuclei
#5109
middle Confidence
Subject:
cytologic_study
(Diagnostic techniques)
→
was_carried_out_on
→
Object:
ovarian_cyst_contents
(Clinical samples)
Original: A cytologic study#was carried out on#contents of 62 ovarian cysts
#5094
middle Confidence
Subject:
CD23
(Immune differentiation antigens)
→
is_downregulated_in
→
Object:
tumors
(Tumor cells)
Original: CD23 antigen#was either negative or weakly present in#tumors
#5093
middle Confidence
Subject:
TdT
(DNA polymerase)
→
is_not_expressed_in
→
Object:
progenitor_cells
(Hematopoietic progenitor cells)
Original: CD34 and TdT#were not expressed in#progenitor cells
#5092
middle Confidence
Subject:
CD34
(Hematopoietic stem cell markers)
→
is_not_expressed_in
→
Object:
progenitor_cells
(Hematopoietic progenitor cells)
Original: CD34 and TdT#were not expressed in#progenitor cells
#5069
middle Confidence
Subject:
B-PLL
(Tumor cells)
→
is_distinguishable_from
→
Object:
B-acute_lymphoblastic_leukaemia
(Tumor cells)
Original: B-PLL#is distinguishable from#other B-cell malignancies
#5068
middle Confidence
Subject:
B-PLL
(Tumor cells)
→
is_distinguishable_from
→
Object:
B-CLL
(Tumor cells)
Original: B-PLL#is distinguishable from#other B-cell malignancies
#5067
middle Confidence
Subject:
B-PLL
(Tumor cells)
→
is_distinguishable_from
→
Object:
follicular_lymphoma
(Tumor cells)
Original: B-PLL#is distinguishable from#other B-cell malignancies
#5054
middle Confidence
Subject:
Primary_histiocytic_lymphoma_of_bone
(disease)
→
is_indistinguishable_from
→
Object:
extranodal_lymphoma
(disease)
Original: Primary histiocytic lymphoma of bone#is indistinguishable from#nodular and diffuse large cell nodular and extranodal lymphomas
#5053
middle Confidence
Subject:
Primary_histiocytic_lymphoma_of_bone
(disease)
→
is_indistinguishable_from
→
Object:
diffuse_large_cell_lymphoma
(disease)
Original: Primary histiocytic lymphoma of bone#is indistinguishable from#nodular and diffuse large cell nodular and extranodal lymphomas
#5052
middle Confidence
Subject:
Primary_histiocytic_lymphoma_of_bone
(disease)
→
is_indistinguishable_from
→
Object:
nodular_large_cell_lymphoma
(disease)
Original: Primary histiocytic lymphoma of bone#is indistinguishable from#nodular and diffuse large cell nodular and extranodal lymphomas
#5023
middle Confidence
Subject:
Cg
(Chromogranin A)
→
shows_weak_staining_in
→
Object:
tumors
(Tumor)
Original: Immunostaining#reveals#positive NSE reactivity in 10/10 tumors and weak CgA staining in 4/10 tumors
#5019
middle Confidence
Subject:
malignant_tumor_cells
(Tumor cells)
→
tend_to_be
→
Object:
less_cohesive
(Morphological characteristics)
Original: Cells from benign tumors#tend to be#smaller and more cohesive than malignant ones
#5018
middle Confidence
Subject:
malignant_tumor_cells
(Tumor cells)
→
tend_to_be
→
Object:
larger
(Morphological characteristics)
Original: Cells from benign tumors#tend to be#smaller and more cohesive than malignant ones
#5017
middle Confidence
Subject:
benign_tumor_cells
(Tumor cells)
→
tend_to_be
→
Object:
more_cohesive
(Morphological characteristics)
Original: Cells from benign tumors#tend to be#smaller and more cohesive than malignant ones
#5016
middle Confidence
Subject:
benign_tumor_cells
(Tumor cells)
→
tend_to_be
→
Object:
smaller
(Morphological characteristics)
Original: Cells from benign tumors#tend to be#smaller and more cohesive than malignant ones
#5007
middle Confidence
Subject:
cytophotometric_DNA_content
(DNA content)
→
is_related_to
→
Object:
PCNA
(Proliferation-related proteins)
Original: Cytophotometric DNA content#is related to#AgNOR and PCNA in oesophageal cancer
#5006
middle Confidence
Subject:
cytophotometric_DNA_content
(DNA content)
→
is_related_to
→
Object:
AgNOR
(Morphological markers)
Original: Cytophotometric DNA content#is related to#AgNOR and PCNA in oesophageal cancer
#4989
middle Confidence
Subject:
Ag-NOR_frequency
(Nucleolar organizer region marker)
→
shows_no_variation_in
→
Object:
intestinal_cancer_patients
(Patient phenotype)
Original: Ag-NOR frequencies#show no variation in#intestinal cancer patients
#4974
middle Confidence
Subject:
cell
(cell)
→
expresses
→
Object:
NF
(Neurofilament protein)
Original: The cells#were#NSE- and NF-positive
#4973
middle Confidence
Subject:
cell
(cell)
→
expresses
→
Object:
NSE
(Neuron-specific enolase)
Original: The cells#were#NSE- and NF-positive
#4971
middle Confidence
Subject:
nevi
(Skin lesions)
→
were_diagnosed_as
→
Object:
NAD
(Skin lesion subtype)
Original: 6/275 nevi#were diagnosed as#NAD
#4968
middle Confidence
Subject:
tumor_shadow
(Imaging findings)
→
was_revealed_in
→
Object:
right_kidney
(organ)
Original: tumor shadow#was revealed in#the right kidney during ultrasonographic examination
#4928
middle Confidence
Subject:
papillary_thyroid_carcinoma
(Tumor type)
→
is_reported_in
→
Object:
thyroid
(organ)
Original: mammary analog secretory carcinoma (MASC)#arises in#thyroid
#4916
middle Confidence
Subject:
IG_DCIS
(Disease Type)
→
showed
→
Object:
intermediate_features_between_LG_and_HG_DCIS
(Disease phenotype)
Original: IG DCIS#showed#intermediate features between LG and HG DCIS/ including 3-dimensional sheets with punched-out spaces/ abundant single cells/ moderate pleomorphism/ and focal necrosis
#4889
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
were_arranged_in
→
Object:
nests
(Organizational Structure)
Original: Malignant cells#were arranged in#sheets and nests
#4888
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
were_arranged_in
→
Object:
sheets
(Organizational Structure)
Original: Malignant cells#were arranged in#sheets and nests
#4887
middle Confidence
Subject:
pseudopapillary_structures
(Histological morphology)
→
formed
→
Object:
dominant_pattern
(Histological characteristics)
Original: Pseudopapillary structures#formed#dominant pattern in squash preparations
#4884
middle Confidence
Subject:
Immunohistochemical_stains
(Detection Methods)
→
play_important_role_in
→
Object:
Thyroglobulin
(protein)
Original: immunohistochemical stains#play an important role in#difficult cases of calcitonin and thyroglobulin
#4883
middle Confidence
Subject:
Immunohistochemical_stains
(Detection Methods)
→
play_important_role_in
→
Object:
calcitonin
(hormone)
Original: immunohistochemical stains#play an important role in#difficult cases of calcitonin and thyroglobulin
#4882
middle Confidence
Subject:
renal_angiomyolipoma
(Tumor type)
→
is_characterized_by
→
Object:
thick-walled_blood_vessels
(Tissue composition)
Original: renal angiomyolipoma#is#a benign tumor histologically characterized by adipose tissue/ smooth muscle cells/ and thick-walled blood vessels
#4881
middle Confidence
Subject:
renal_angiomyolipoma
(Tumor type)
→
is_characterized_by
→
Object:
smooth_muscle_cells
(Tissue composition)
Original: renal angiomyolipoma#is#a benign tumor histologically characterized by adipose tissue/ smooth muscle cells/ and thick-walled blood vessels
#4880
middle Confidence
Subject:
renal_angiomyolipoma
(Tumor type)
→
is_characterized_by
→
Object:
adipose_tissue
(Tissue composition)
Original: renal angiomyolipoma#is#a benign tumor histologically characterized by adipose tissue/ smooth muscle cells/ and thick-walled blood vessels
#4866
middle Confidence
Subject:
protein_A-gold_immunocytochemistry
(Immunoassay technology)
→
is_used_to_investigate
→
Object:
expression_of_diagnostically_useful_antibodies
(Antibody expression)
Original: Postembedding protein A-gold immunocytochemistry#is used to investigate#expression and ultrastructural localization of diagnostically useful antibodies
#4865
middle Confidence
Subject:
Infiltrative_growth_pattern
(Organizational form)
→
was_present_in
→
Object:
prostate_foci
(Organizational Structure)
Original: Infiltrative growth pattern#was present in#27 foci (19%)
#4864
middle Confidence
Subject:
Crystalloids
(Intracellular structure)
→
were_present_in
→
Object:
prostate_foci
(Organizational Structure)
Original: Crystalloids#were present in#58 foci (40%)
#4852
middle Confidence
Subject:
low_molecular_weight_keratin_protein_K11
(Keratin)
→
shows_moderate_positivity_in
→
Object:
vesicular_nuclear_cell_carcinoma
(Tumor type)
Original: Immunocytochemical studies#proved#moderate positivity for low molecular weight keratin protein (K10/11)
#4851
middle Confidence
Subject:
low_molecular_weight_keratin_protein_K10
(Keratin)
→
shows_moderate_positivity_in
→
Object:
poorly_differentiated_squamous_cell_carcinoma
(Tumor type)
Original: Immunocytochemical studies#proved#moderate positivity for low molecular weight keratin protein (K10/11)
#4850
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_arranged_in
→
Object:
tubular_pattern
(Organizational Structure)
Original: Tumor cells#are arranged in#a trabecular or tubular pattern with eosinophilic cytoplasm
#4849
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_arranged_in
→
Object:
trabecular_pattern
(Organizational Structure)
Original: Tumor cells#are arranged in#a trabecular or tubular pattern with eosinophilic cytoplasm
#4847
middle Confidence
Subject:
pulmonary_alveolar_spaces
(Alveolar structure)
→
contain
→
Object:
anaplastic_cells
(Tumor cells)
Original: Pulmonary alveolar spaces#contained#clusters of large round anaplastic cells with prominent nucleoli
#4822
middle Confidence
Subject:
Trichomonas
(Parasitic protozoa)
→
is_identified_by
→
Object:
participants
(Study participants)
Original: Trichomonas#is identified by#some participants
#4820
middle Confidence
Subject:
glial_fibrillary_acidic_protein
(protein)
→
not_detected_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: glial fibrillary acidic protein#was not detected in#neoplastic cells
#4810
middle Confidence
Subject:
Cytologic_material
(Cytology samples)
→
was_analyzed_for
→
Object:
Sensitivity_and_specificity_of_criteria_for_papillary_carcinoma
(Diagnostic criteria)
Original: cytologic material#was analyzed for#sensitivity and specificity of criteria for papillary carcinoma
#4787
middle Confidence
Subject:
mucin_positivity
(Molecular markers)
→
was_identified_in
→
Object:
all_cases
(Case Collection)
Original: Mucin positivity#was identified in#all six cases
#4786
middle Confidence
Subject:
tumors
(Tumor tissue)
→
ranged_in_size_from
→
Object:
4_to_6_cm
(Tumor size characteristics)
Original: tumors#ranged in size from#4 to 6 cm and appeared white and solid; necrosis was apparent in two tumors
#4785
middle Confidence
Subject:
cells
(Tumor cells)
→
have
→
Object:
small_nucleolus
(Cell morphology)
Original: cells#have#vague boundaries/ circular nuclei/ fine chromatin/ and a small nucleolus
#4784
middle Confidence
Subject:
cells
(Tumor cells)
→
have
→
Object:
fine_chromatin
(Cell morphology)
Original: cells#have#vague boundaries/ circular nuclei/ fine chromatin/ and a small nucleolus
#4783
middle Confidence
Subject:
cells
(Tumor cells)
→
have
→
Object:
circular_nuclei
(Cell morphology)
Original: cells#have#vague boundaries/ circular nuclei/ fine chromatin/ and a small nucleolus
#4782
middle Confidence
Subject:
cells
(Tumor cells)
→
have
→
Object:
vague_boundaries
(Cell morphology)
Original: cells#have#vague boundaries/ circular nuclei/ fine chromatin/ and a small nucleolus
#4745
middle Confidence
Subject:
Computed tomography
(Imaging tests)
→
reveals
→
Object:
Calculation
(Imaging signs)
Original: Computed tomography#revealed#a giant tumor attached to the parietal pleura with calcification
#4744
middle Confidence
Subject:
Computed tomography
(Imaging tests)
→
reveals
→
Object:
giant tumor
(Tumor phenotype)
Original: Computed tomography#revealed#a giant tumor attached to the parietal pleura with calcification
#4727
middle Confidence
Subject:
Variants_of_epithelial-myoepithelial_carcinoma
(Disease phenotype)
→
raise
→
Object:
differential_diagnostic_considerations
(Clinical characteristics)
Original: Variants of epithelial-myoepithelial carcinoma#raise#a distinct set of differential diagnostic considerations
#4722
middle Confidence
Subject:
Smears
(Cytology)
→
revealed
→
Object:
small_mature_round_lymphocytes
(Lymphocytes)
Original: Smears#revealed#small mature round lymphocytes
#4721
middle Confidence
Subject:
CT_scan
(Imaging tests)
→
revealed
→
Object:
liver_lesions
(Tumor lesions)
Original: CT scan#revealed#multiple omental masses and liver lesions
#4720
middle Confidence
Subject:
CT_scan
(Imaging tests)
→
revealed
→
Object:
multiple_omental_masses
(Tumor lesions)
Original: CT scan#revealed#multiple omental masses and liver lesions
#4719
middle Confidence
Subject:
criteria
(Diagnostic criteria)
→
are_developed_for
→
Object:
grading_NAD
(Diagnostic classification)
Original: criteria#have been developed for#grading NAD into mild/ moderate/ and severe
#4715
middle Confidence
Subject:
spindle_cell_proliferations_of_the_thyroid
(Cellular Processes)
→
associated_with
→
Object:
reactive_processes
(Reactive pathological process)
Original: spindle cell proliferations of the thyroid#have been described in association with#reactive processes and aggressive malignant neoplasms
#4714
middle Confidence
Subject:
classic_cases_of_MC_of_the_breast
(Disease phenotype)
→
display
→
Object:
relatively_uniform_appearance
(Histological morphology)
Original: classic cases of MC of the breast#display#a relatively uniform appearance
#4711
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
have
→
Object:
protruding_nucleoli
(Nucleolar protrusion)
Original: tumor cells#have#irregular nuclei/ protruding nucleoli/ advanced stage at diagnosis/ and shorter clinical course
#4710
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
have
→
Object:
irregular_nuclei
(Abnormal nuclear morphology)
Original: tumor cells#have#irregular nuclei/ protruding nucleoli/ advanced stage at diagnosis/ and shorter clinical course
#4700
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
express
→
Object:
micropthalmia_transcription_factor
(Transcription Factors)
Original: neoplastic cells#express#NKI-C3/ CD10/ and micropthalmia transcription factor
#4699
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
express
→
Object:
CD10
(protein)
Original: neoplastic cells#express#NKI-C3/ CD10/ and micropthalmia transcription factor
#4698
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
express
→
Object:
NKI-C3
(protein)
Original: neoplastic cells#express#NKI-C3/ CD10/ and micropthalmia transcription factor
#4693
middle Confidence
Subject:
AgNOR_enumeration
(Molecular marker detection)
→
is_of_limited_use_in
→
Object:
grading_of_bladder_transitional_cell_tumor
(Tumor grade)
Original: Enumeration of Ag-NORs#is of limited use#in grading transitional cell tumors of the bladder
#4688
middle Confidence
Subject:
IPT-like_FDC_tumor
(Tumor Entities)
→
is_characterized_by
→
Object:
EBV-positive_FDC_proliferation
(Cellular Processes)
Original: IPT-like FDC tumor#is characterized by#proliferation of EBV-positive FDC
#4673
middle Confidence
Subject:
N/C_ratio
(Cell morphology parameters)
→
is_not_increased_in
→
Object:
tumor
(Tumor tissue)
Original: N/C ratio#is not increased in#tumor
#4669
middle Confidence
Subject:
IG_DCIS
(Disease Type)
→
included
→
Object:
focal_necrosis
(Necrotic characteristics)
Original: IG DCIS#showed#intermediate features between LG and HG DCIS/ including 3-dimensional sheets with punched-out spaces/ abundant single cells/ moderate pleomorphism/ and focal necrosis
#4668
middle Confidence
Subject:
IG_DCIS
(Disease Type)
→
included
→
Object:
moderate_pleomorphism
(Cytological characteristics)
Original: IG DCIS#showed#intermediate features between LG and HG DCIS/ including 3-dimensional sheets with punched-out spaces/ abundant single cells/ moderate pleomorphism/ and focal necrosis
#4667
middle Confidence
Subject:
IG_DCIS
(Disease Type)
→
included
→
Object:
abundant_single_cells
(Cytological characteristics)
Original: IG DCIS#showed#intermediate features between LG and HG DCIS/ including 3-dimensional sheets with punched-out spaces/ abundant single cells/ moderate pleomorphism/ and focal necrosis
#4666
middle Confidence
Subject:
IG_DCIS
(Disease Type)
→
included
→
Object:
3D_sheets_with_punched-out_spaces
(Cell structure characteristics)
Original: IG DCIS#showed#intermediate features between LG and HG DCIS/ including 3-dimensional sheets with punched-out spaces/ abundant single cells/ moderate pleomorphism/ and focal necrosis
#4665
middle Confidence
Subject:
Cytologic_findings_of_HG_DCIS
(Cell morphology)
→
included
→
Object:
Necrosis
(Necrotic characteristics)
Original: Cytologic findings of HG DCIS#included#high cellularity/ clusters of pleomorphic cells with large nuclei and increased nuclear/cytoplasmic ratios/ single cells/ prominent nucleoli/ and necrosis
#4664
middle Confidence
Subject:
Cytologic_findings_of_HG_DCIS
(Cell morphology)
→
included
→
Object:
prominent_nucleoli
(Cytological characteristics)
Original: Cytologic findings of HG DCIS#included#high cellularity/ clusters of pleomorphic cells with large nuclei and increased nuclear/cytoplasmic ratios/ single cells/ prominent nucleoli/ and necrosis
#4663
middle Confidence
Subject:
Cytologic_findings_of_HG_DCIS
(Cell morphology)
→
included
→
Object:
single_cells
(Cytological characteristics)
Original: Cytologic findings of HG DCIS#included#high cellularity/ clusters of pleomorphic cells with large nuclei and increased nuclear/cytoplasmic ratios/ single cells/ prominent nucleoli/ and necrosis
#4662
middle Confidence
Subject:
Cytologic_findings_of_HG_DCIS
(Cell morphology)
→
included
→
Object:
clusters_of_pleomorphic_cells_with_large_nuclei
(Cytological characteristics)
Original: Cytologic findings of HG DCIS#included#high cellularity/ clusters of pleomorphic cells with large nuclei and increased nuclear/cytoplasmic ratios/ single cells/ prominent nucleoli/ and necrosis
#4661
middle Confidence
Subject:
Cytologic_findings_of_HG_DCIS
(Cell morphology)
→
included
→
Object:
high_cellularity
(Cytological characteristics)
Original: Cytologic findings of HG DCIS#included#high cellularity/ clusters of pleomorphic cells with large nuclei and increased nuclear/cytoplasmic ratios/ single cells/ prominent nucleoli/ and necrosis
#4659
middle Confidence
Subject:
tall_cell_variant
(Tumor subtype)
→
needs_differentiation_from
→
Object:
Hürthle_cell_papillary_neoplasm_of_thyroid
(Tumor subtype)
Original: tall cell variant#needs differentiation from#Hürthle cell papillary neoplasm of thyroid
#4658
middle Confidence
Subject:
angiosarcoma
(Tumor type)
→
was_ruled_out_with
→
Object:
silver_impregnation_technique
(Pathological detection methods)
Original: angiosarcoma#was ruled out with#a silver impregnation technique
#4657
middle Confidence
Subject:
mucin
(Glycoprotein)
→
was_negative_in
→
Object:
tumor_cells
(Tumor cells)
Original: mucin#was#negative in tumor cells
#4625
middle Confidence
Subject:
protein_A-gold_immunocytochemistry
(Immunoassay technology)
→
is_used_to_investigate
→
Object:
ultrastructural_localization_of_diagnostically_useful_antibodies
(Subcellular localization)
Original: Postembedding protein A-gold immunocytochemistry#is used to investigate#expression and ultrastructural localization of diagnostically useful antibodies
#4622
middle Confidence
Subject:
Prominent_nucleoli
(Nuclear structure)
→
were_present_in
→
Object:
prostate_foci
(Organizational Structure)
Original: Prominent nucleoli#were present in#22 foci (15%)
#4620
middle Confidence
Subject:
coarse_chromatin
(Coarse granular chromatin)
→
are_less_useful_for
→
Object:
diagnosis
(diagnosis)
Original: Mitotic figures/ necrotic cells/ and coarse chromatin#are less useful for#diagnosis
#4619
middle Confidence
Subject:
necrotic_cells
(Necrotic cells)
→
are_less_useful_for
→
Object:
diagnosis
(diagnosis)
Original: Mitotic figures/ necrotic cells/ and coarse chromatin#are less useful for#diagnosis
#4618
middle Confidence
Subject:
Mitotic_figures
(Mitotic figures)
→
are_less_useful_for
→
Object:
diagnosis
(diagnosis)
Original: Mitotic figures/ necrotic cells/ and coarse chromatin#are less useful for#diagnosis
#4613
middle Confidence
Subject:
benign_entity
(Benign lesions)
→
is_recognized_by
→
Object:
inflammation
(Inflammatory response)
Original: benign entity#is recognized by#characteristic mixture of various architectural patterns
#4612
middle Confidence
Subject:
benign_entity
(Benign lesions)
→
is_recognized_by
→
Object:
stromal_edema
(Tissue Microenvironment)
Original: benign entity#is recognized by#characteristic mixture of various architectural patterns
#4611
middle Confidence
Subject:
benign_entity
(Benign lesions)
→
is_recognized_by
→
Object:
mixture_of_architectural_patterns
(Organizational Structure)
Original: benign entity#is recognized by#characteristic mixture of various architectural patterns
#4610
middle Confidence
Subject:
adrenal_foci
(Tumor lesions)
→
consist_of
→
Object:
scattered_cells_with_eosinophilic_granular_cytoplasm
(Cell Type)
Original: adrenal foci#consist of#clear cells and scattered cells with eosinophilic/ granular cytoplasm
#4609
middle Confidence
Subject:
adrenal_foci
(Tumor lesions)
→
consist_of
→
Object:
clear_cells
(Cell Type)
Original: adrenal foci#consist of#clear cells and scattered cells with eosinophilic/ granular cytoplasm
#4595
middle Confidence
Subject:
adenoid_basal_carcinoma
(Tumor type)
→
includes
→
Object:
three-dimensional_cell_groups_with_overlapping_nuclei
(Cytological characteristics)
Original: adenoid basal carcinoma#includes#three-dimensional groups of intact cells with overlapping nuclei
#4592
middle Confidence
Subject:
SDC
(disease)
→
has_feature
→
Object:
background_necrosis
(Characteristics of tissue necrosis)
Original: Cytomorphologic features of SDC#include#cellular smears/ nuclear atypia/ prominent nucleoli/ cribriform and papillary architecture/ and background necrosis
#4591
middle Confidence
Subject:
SDC
(disease)
→
has_feature
→
Object:
papillary_architecture
(Organizational structure characteristics)
Original: Cytomorphologic features of SDC#include#cellular smears/ nuclear atypia/ prominent nucleoli/ cribriform and papillary architecture/ and background necrosis
#4590
middle Confidence
Subject:
SDC
(disease)
→
has_feature
→
Object:
cribriform_architecture
(Organizational structure characteristics)
Original: Cytomorphologic features of SDC#include#cellular smears/ nuclear atypia/ prominent nucleoli/ cribriform and papillary architecture/ and background necrosis
#4589
middle Confidence
Subject:
SDC
(disease)
→
has_feature
→
Object:
prominent_nucleolus
(Nucleolar characteristics)
Original: Cytomorphologic features of SDC#include#cellular smears/ nuclear atypia/ prominent nucleoli/ cribriform and papillary architecture/ and background necrosis
#4588
middle Confidence
Subject:
SDC
(disease)
→
has_feature
→
Object:
nuclear_atypia
(Nuclear abnormalities)
Original: Cytomorphologic features of SDC#include#cellular smears/ nuclear atypia/ prominent nucleoli/ cribriform and papillary architecture/ and background necrosis
#4587
middle Confidence
Subject:
SDC
(disease)
→
has_feature
→
Object:
cellular_smear
(Cell morphology)
Original: Cytomorphologic features of SDC#include#cellular smears/ nuclear atypia/ prominent nucleoli/ cribriform and papillary architecture/ and background necrosis
#4580
middle Confidence
Subject:
Bronchial_washing
(Cytology samples)
→
reveals
→
Object:
small_round_cells
(Cell morphology)
Original: Bronchial washing#reveals#small round cells with uniform nuclei and inconspicuous nucleoli
#4554
middle Confidence
Subject:
metastatic_intraocular_tumors
(Tumor type)
→
can_be_differentiated_in
→
Object:
cytologic_preparations
(Diagnostic sample type)
Original: Primary and metastatic intraocular tumors#can be differentiated in#cytologic preparations
#4553
middle Confidence
Subject:
primary_intraocular_tumors
(Tumor type)
→
can_be_differentiated_in
→
Object:
cytologic_preparations
(Diagnostic sample type)
Original: Primary and metastatic intraocular tumors#can be differentiated in#cytologic preparations
#4550
middle Confidence
Subject:
ocular_tumors
(Tumor type)
→
were_examined_for
→
Object:
histopathologic_correlates
(Histopathological features)
Original: ocular tumors#were examined for#cytologic and histopathologic correlates
#4549
middle Confidence
Subject:
ocular_tumors
(Tumor type)
→
were_examined_for
→
Object:
cytologic_correlates
(Cytological characteristics)
Original: ocular tumors#were examined for#cytologic and histopathologic correlates
#4544
middle Confidence
Subject:
cellular_pleomorphism
(Cellular heterogeneity)
→
was_not_marked_in
→
Object:
observed_tumors
(Tumor tissue)
Original: cellular pleomorphism#was not marked in#the observed tumors
#4543
middle Confidence
Subject:
Necrosis
(Necrosis)
→
was_apparent_in
→
Object:
two_tumors
(Tumor tissue)
Original: tumors#ranged in size from#4 to 6 cm and appeared white and solid; necrosis was apparent in two tumors
#4542
middle Confidence
Subject:
tumors
(Tumor tissue)
→
appeared
→
Object:
white_and_solid
(Tissue appearance characteristics)
Original: tumors#ranged in size from#4 to 6 cm and appeared white and solid; necrosis was apparent in two tumors
#4541
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
include
→
Object:
many_mitoses
(Cell proliferation characteristics)
Original: cytologic features#include#sparse cytoplasm/ dispersed chromatin/ inconspicuous nucleoli/ and many mitoses
#4540
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
include
→
Object:
inconspicuous_nucleoli
(Cell morphology)
Original: cytologic features#include#sparse cytoplasm/ dispersed chromatin/ inconspicuous nucleoli/ and many mitoses
#4539
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
include
→
Object:
dispersed_chromatin
(Cell morphology)
Original: cytologic features#include#sparse cytoplasm/ dispersed chromatin/ inconspicuous nucleoli/ and many mitoses
#4538
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
include
→
Object:
sparse_cytoplasm
(Cell morphology)
Original: cytologic features#include#sparse cytoplasm/ dispersed chromatin/ inconspicuous nucleoli/ and many mitoses
#4537
middle Confidence
Subject:
perinuclear_dense_round_cytoplasmic_condensation
(Cytoplasmic structure)
→
was_observed_in
→
Object:
some_cases_in_absence_of_intracytoplasmic_luminae
(Cell morphology)
Original: perinuclear dense round cytoplasmic condensation#was observed in#some cases in the absence of intracytoplasmic luminae
#4508
middle Confidence
Subject:
Isolated_observation
(Diagnostic Methods)
→
will_not_differentiate
→
Object:
Ewing's_sarcoma
(disease)
Original: Isolated observation#will not differentiate#histiocytic lymphoma from Ewing's sarcoma
#4507
middle Confidence
Subject:
Isolated_observation
(Diagnostic Methods)
→
will_not_differentiate
→
Object:
histiocytic_lymphoma
(disease)
Original: Isolated observation#will not differentiate#histiocytic lymphoma from Ewing's sarcoma
#4498
middle Confidence
Subject:
FRMs
(Myofiber-associated cells)
→
stained_for
→
Object:
muscle-specific_actin
(Myoactin)
Original: FRMs#typically stained for#myoglobin/ desmin/ and muscle-specific actin
#4497
middle Confidence
Subject:
FRMs
(Myofiber-associated cells)
→
stained_for
→
Object:
desmin
(Vimentin)
Original: FRMs#typically stained for#myoglobin/ desmin/ and muscle-specific actin
#4496
middle Confidence
Subject:
FRMs
(Myofiber-associated cells)
→
stained_for
→
Object:
myoglobin
(Myoglobin)
Original: FRMs#typically stained for#myoglobin/ desmin/ and muscle-specific actin
#4487
middle Confidence
Subject:
tumors
(Tumor)
→
consist_of
→
Object:
intraductal_proliferation
(Intraductal hyperplasia)
Original: Tumors#consist of#single to multiple dominant cysts with adjacent intraductal proliferation
#4486
middle Confidence
Subject:
tumors
(Tumor)
→
consist_of
→
Object:
dominant_cysts
(Cystic structure)
Original: Tumors#consist of#single to multiple dominant cysts with adjacent intraductal proliferation
#4466
low Confidence
Subject:
Tumor_cells
(Tumor cells)
→
form
→
Object:
cell_clusters
(Cell structure)
Original: Tumor cells#were in#clusters in scraping and fine needle aspiration smears
#4447
low Confidence
Subject:
62-year-old_man
(patient)
→
presented_with
→
Object:
multifocal_osteolytic_lesions
(Bone lesions)
Original: A 62-year-old man#presented with#multifocal osteolytic lesions in the extremities and the pelvis
#4436
low Confidence
Subject:
spindle cell thymoma
(Tumor type)
→
was_suggested_by
→
Object:
Cytology based on location
(Diagnostic techniques/conditions)
Original: The possibility of spindle cell thymoma#was suggested#on cytology based on location
#4332
low Confidence
Subject:
skin_infiltration_of_AML
(Cell infiltration)
→
may_precede
→
Object:
systemic_evidence
(Disease phenotype)
Original: Skin infiltration of AML#may precede#systemic evidence
#4299
middle Confidence
Subject:
adipocytes
(Fat cells)
→
are_encircled_by
→
Object:
neoplastic_lymphocytes
(Tumor cells)
Original: Adipocytes#were encircled by#neoplastic lymphocytes
#4242
low Confidence
Subject:
nodular_sclerosis_Hodgkin's_disease
(Tumor type)
→
shows
→
Object:
IDC_like_cell_type
(Cell phenotype)
Original: nodular sclerosis Hodgkin's disease#showed#another cell type resembling IDC
#4204
low Confidence
Subject:
preoperative_cytology
(Preoperative cytology)
→
was_reported_in
→
Object:
19_cases
(Case)
Original: preoperative cytology#was reported in#19 cases up to date
#4136
low Confidence
Subject:
physical_examination
(Physical examination)
→
revealed
→
Object:
low-grade_fever
(symptom)
Original: Physical examination#revealed#low-grade fever
#4038
low Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_detected_in
→
Object:
fine_needle_aspiration_smears
(Test sample type)
Original: Tumor cells#were in#clusters in scraping and fine needle aspiration smears
#4037
low Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_detected_in
→
Object:
scraping_smears
(Test sample type)
Original: Tumor cells#were in#clusters in scraping and fine needle aspiration smears
#4036
low Confidence
Subject:
Adenocarcinoma_of_Bartholin's_gland
(Tumor diseases)
→
is_characterized_by
→
Object:
histologic_findings
(Morphological characteristics)
Original: Adenocarcinoma of Bartholin's gland#was described in#cytologic and histologic findings
#4035
low Confidence
Subject:
Adenocarcinoma_of_Bartholin's_gland
(Tumor diseases)
→
is_characterized_by
→
Object:
cytologic_findings
(Morphological characteristics)
Original: Adenocarcinoma of Bartholin's gland#was described in#cytologic and histologic findings
#4018
low Confidence
Subject:
analyzed_parameter_4
(Cell morphological parameters)
→
cannot_alone_discriminate
→
Object:
neoplastic_cells
(Tumor cells)
Original: Four analyzed parameters#cannot alone discriminate#neoplastic from normal cells in pancreatic cancer
#4017
low Confidence
Subject:
analyzed_parameter_3
(Cell morphological parameters)
→
cannot_alone_discriminate
→
Object:
neoplastic_cells
(Tumor cells)
Original: Four analyzed parameters#cannot alone discriminate#neoplastic from normal cells in pancreatic cancer
#4016
low Confidence
Subject:
analyzed_parameter_2
(Cell morphological parameters)
→
cannot_alone_discriminate
→
Object:
neoplastic_cells
(Tumor cells)
Original: Four analyzed parameters#cannot alone discriminate#neoplastic from normal cells in pancreatic cancer
#4015
low Confidence
Subject:
analyzed_parameter_1
(Cell morphological parameters)
→
cannot_alone_discriminate
→
Object:
neoplastic_cells
(Tumor cells)
Original: Four analyzed parameters#cannot alone discriminate#neoplastic from normal cells in pancreatic cancer
#4002
low Confidence
Subject:
NOR_protein_proteolysis
(Protein degradation process)
→
may_identify
→
Object:
early_apoptosis_stage
(Apoptosis stage)
Original: Differential proteolysis of NOR proteins#may identify#early stages of apoptosis
#3989
low Confidence
Subject:
AgNOR_count
(Nuclear Organism Markers)
→
shows_significant_difference_in
→
Object:
cytological_sample_2
(Cytology samples)
Original: AgNOR counts#showed#a significant difference in two cytological samples
#3988
low Confidence
Subject:
AgNOR_count
(Nuclear Organism Markers)
→
shows_significant_difference_in
→
Object:
cytological_sample_1
(Cytology samples)
Original: AgNOR counts#showed#a significant difference in two cytological samples
#3947
low Confidence
Subject:
Atypical_type_HAPCA_case
(Case Type)
→
had
→
Object:
scattered_proliferation_of_nest-like_nodules
(Abnormal cell structure)
Original: Atypical type HAPCA case#had#extensive islet hyperplasia and scattered proliferation of nest-like nodules
#3946
low Confidence
Subject:
Atypical_type_HAPCA_case
(Case Type)
→
had
→
Object:
islet_hyperplasia
(Cell proliferation)
Original: Atypical type HAPCA case#had#extensive islet hyperplasia and scattered proliferation of nest-like nodules
#3926
low Confidence
Subject:
malignant_mesothelioma
(Malignant tumors)
→
can_present_in
→
Object:
patients_with_nonrespiratory_complaints
(Patient characteristics)
Original: Malignant mesothelioma#can present in#unusual sites and patients with nonrespiratory complaints
#3925
low Confidence
Subject:
malignant_mesothelioma
(Malignant tumors)
→
can_present_in
→
Object:
unusual_sites
(Anatomical location)
Original: Malignant mesothelioma#can present in#unusual sites and patients with nonrespiratory complaints
#3924
low Confidence
Subject:
male_patient_51_years
(Patient characteristics)
→
presented_with
→
Object:
knee_mass_5cm
(Clinical symptoms)
Original: A 51-year-old male#presented with#a 5 cm left knee mass
#3886
low Confidence
Subject:
Clinical_and_pathological_features
(Disease phenotype)
→
overlap_with
→
Object:
soft_tissue_sarcomas
(Tumor)
Original: Clinical and pathological features#overlap with#Ewing sarcoma family and other soft tissue sarcomas
#3885
low Confidence
Subject:
Clinical_and_pathological_features
(Disease phenotype)
→
overlap_with
→
Object:
Ewing_sarcoma_family
(Tumor)
Original: Clinical and pathological features#overlap with#Ewing sarcoma family and other soft tissue sarcomas
#3867
low Confidence
Subject:
adenocarcinoma_cells
(Tumor cells)
→
have
→
Object:
slightly_larger_nuclei_than_borderline_cells
(Nuclear characteristics)
Original: Adenocarcinoma cells#have#slightly larger nuclei than borderline cells
#3865
low Confidence
Subject:
ossifying_fibroma
(Osteofibroma)
→
was_initially_diagnosed_as
→
Object:
entity_in_mandible
(Tumor Entities)
Original: A case of this entity#was reported in#the mandible/ initially diagnosed as ossifying fibroma
#3857
low Confidence
Subject:
Tumor_areas
(Tumor tissue)
→
show_differentiation_toward
→
Object:
Squamous_cell_carcinoma
(Tumor type)
Original: No areas#show differentiation toward#adenocarcinoma or squamous cell carcinoma
#3856
low Confidence
Subject:
Tumor_areas
(Tumor tissue)
→
show_differentiation_toward
→
Object:
Adenocarcinoma
(Tumor type)
Original: No areas#show differentiation toward#adenocarcinoma or squamous cell carcinoma
#3820
low Confidence
Subject:
male_patient_72_years
(Patient characteristics)
→
presented_with
→
Object:
large_temporal_cystic_mass
(Tumor phenotype)
Original: 72-year-old male#presented with#large/ right/ temporal/ cystic mass
#3808
low Confidence
Subject:
one_case
(Case)
→
is_reclassified_as
→
Object:
carcinoma
(cancer)
Original: one case#is reclassified as#carcinoma
#3756
low Confidence
Subject:
patients
(crowd)
→
presented_with
→
Object:
polyuria
(symptom)
Original: Three patients#presented with#symptoms of diabetes insipidus
#3755
low Confidence
Subject:
patients
(crowd)
→
presented_with
→
Object:
polydipsia
(symptom)
Original: Three patients#presented with#symptoms of diabetes insipidus
#3754
low Confidence
Subject:
59_year_old_male_patient
(Patient characteristics)
→
presented_with
→
Object:
Bronchorrhea
(Clinical symptoms)
Original: A 59-year-old man#presented with#cough/ breathlessness/ and bronchorrhea
#3753
low Confidence
Subject:
59_year_old_male_patient
(Patient characteristics)
→
presented_with
→
Object:
breathlessness
(Clinical symptoms)
Original: A 59-year-old man#presented with#cough/ breathlessness/ and bronchorrhea
#3752
low Confidence
Subject:
59_year_old_male_patient
(Patient characteristics)
→
presented_with
→
Object:
cough
(Clinical symptoms)
Original: A 59-year-old man#presented with#cough/ breathlessness/ and bronchorrhea
#3654
low Confidence
Subject:
anterior_uveitis
(Disease phenotype)
→
is_present_in
→
Object:
right_eye
(Organ structure)
Original: A 22-year-old Australian stockhorse gelding#was presented with#anterior uveitis in the right eye
#3653
low Confidence
Subject:
micronuclei
(Cell morphology)
→
are_present_in
→
Object:
aspirates
(Sample Type)
Original: Binucleated cells and micronuclei#were noted in#the aspirates
#3652
low Confidence
Subject:
binucleated_cells
(Cell morphology)
→
are_present_in
→
Object:
aspirates
(Sample Type)
Original: Binucleated cells and micronuclei#were noted in#the aspirates
#3651
low Confidence
Subject:
well-demarcated_tumor
(Tumor pathological entities)
→
extends_into
→
Object:
perithyroidal_soft_tissues
(Organizational Structure)
Original: A 60-year-old Japanese female#had#a well-demarcated tumor extending from the right thyroid lobe into perithyroidal soft tissues
#3645
low Confidence
Subject:
spindle-shaped_cells
(Cell Type)
→
were_noticed_in
→
Object:
YST
(disease)
Original: Spindle-shaped cells#were noticed in#YST
#3616
low Confidence
Subject:
morphological_features
(Morphological characteristics)
→
suggest
→
Object:
biological_relationship_of_tumors
(Tumor Biology Relevance)
Original: Morphological grounds#can suspect#a close biological relationship of these tumors
#3594
low Confidence
Subject:
diagnostic_approach
(Diagnostic strategy)
→
is_discussed_for
→
Object:
primary_Hodgkin_lymphoma
(Malignant tumors)
Original: Diagnostic approach#is discussed for#primary Hodgkin lymphoma in an extremely rare location
#3574
low Confidence
Subject:
cytology_of_microcystic_meningioma
(Cytological characteristics)
→
was_similar_to
→
Object:
cytology_of_metastatic_adenocarcinoma
(Cytological characteristics)
Original: cytology of microcystic meningioma#was similar to#that of metastatic adenocarcinoma
#3523
low Confidence
Subject:
patient
(patient)
→
presented_with
→
Object:
tumor_in_lymph_nodes
(Disease phenotype)
Original: patient#presented with#tumor in lymph nodes
#3514
low Confidence
Subject:
patient
(patient)
→
presented_with
→
Object:
purple_mass_on_scalp
(Clinical symptoms)
Original: the patient#presented with#a purple mass on her scalp
#3498
low Confidence
Subject:
Laminated_psammomatous_calcifications
(Organizational structure)
→
are_abundant_in
→
Object:
psammocarcinoma_case
(Case)
Original: Laminated psammomatous calcifications#were abundant in#3 cases
#3461
low Confidence
Subject:
Ovarian_neoplasm
(Neoplastic diseases)
→
is_reported_as
→
Object:
first_rare_ovarian_neoplasm_on_fluid_cytology
(Diagnostic Events)
Original: This case#is reported as#the first rare ovarian neoplasm present on fluid cytology
#3432
low Confidence
Subject:
Leiomyoblastoma
(Tumor)
→
has
→
Object:
fine_needle_aspiration_cytologic_features
(Cytological characteristics)
Original: The authors#describe#the fine-needle aspiration cytologic features of leiomyoblastoma
#3430
low Confidence
Subject:
nuclei
(Nucleus)
→
contained
→
Object:
prominent_nucleoli
(Nucleolar morphology)
Original: Nuclei#were#globular containing open chromatin and prominent nucleoli
#3429
low Confidence
Subject:
nuclei
(Nucleus)
→
contained
→
Object:
open_chromatin
(Chromatin state)
Original: Nuclei#were#globular containing open chromatin and prominent nucleoli
#3428
low Confidence
Subject:
nuclei
(Nucleus)
→
were
→
Object:
globular_shape
(Nuclear morphology)
Original: Nuclei#were#globular containing open chromatin and prominent nucleoli
#3404
low Confidence
Subject:
nevi
(Benign skin moles)
→
interpreted_as
→
Object:
blue_nevus
(Subtypes of benign skin nevus)
Original: Nevi#were#darkly pigmented/ domed/ and small/ interpreted as blue nevi
#3350
low Confidence
Subject:
cases
(Case)
→
lacked
→
Object:
systemic_evidence_of_leukemia
(Disease phenotype)
Original: 4 cases#presented#typical cutaneous lesions without systemic evidence of leukemia
#3349
low Confidence
Subject:
cases
(Case)
→
presented
→
Object:
cutaneous_lesions
(symptom)
Original: 4 cases#presented#typical cutaneous lesions without systemic evidence of leukemia
#3296
low Confidence
Subject:
cranial_fasciitis
(disease)
→
may_mimic
→
Object:
sarcomatous_process
(Disease phenotype)
Original: CF#may mimic#a sarcomatous process
#3295
low Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
may_help_in
→
Object:
doubtful_cases
(Diagnostic Process)
Original: immunohistochemistry#may help in#doubtful cases
#3261
low Confidence
Subject:
Morphologic_clues
(Morphological clues)
→
correlate_with
→
Object:
data_of_mucinous_variant_of_follicular_neoplasm
(Disease typing data)
Original: Morphologic clues#correlate with#data of mucinous variant of follicular neoplasm
#3255
low Confidence
Subject:
splenomegaly
(symptom)
→
is_observed_in
→
Object:
the_patient
(Patient characteristics)
Original: patient#showed#high abnormal peripheral lymphocytes/ thrombocytopenia/ and splenomegaly
#3254
low Confidence
Subject:
thrombocytopenia
(symptom)
→
is_observed_in
→
Object:
the_patient
(Patient characteristics)
Original: patient#showed#high abnormal peripheral lymphocytes/ thrombocytopenia/ and splenomegaly
#3253
low Confidence
Subject:
abnormal_peripheral_lymphocytes
(Cell Type)
→
are_observed_in
→
Object:
the_patient
(Patient characteristics)
Original: patient#showed#high abnormal peripheral lymphocytes/ thrombocytopenia/ and splenomegaly
#3248
low Confidence
Subject:
splenomegaly
(symptom)
→
is_observed_in
→
Object:
the_patient
(Patient characteristics)
Original: splenomegaly#is observed in#the patient
#3191
low Confidence
Subject:
Benign_tumor_cells
(Tumor cells)
→
may_mimic
→
Object:
Certain_benign_or_malignant_neoplasms
(Tumor cells)
Original: The histologic features of this benign tumor#may mimic#those of certain benign or malignant neoplasms
#3185
low Confidence
Subject:
Myxoid_MM
(Disease name)
→
mimics
→
Object:
pseudomyxoma_peritonei
(Disease name)
Original: Myxoid MM#mimics#mucinous carcinomas or pseudomyxoma peritonei
#3184
low Confidence
Subject:
Myxoid_MM
(Disease name)
→
mimics
→
Object:
mucinous_carcinomas
(Disease name)
Original: Myxoid MM#mimics#mucinous carcinomas or pseudomyxoma peritonei
#3178
low Confidence
Subject:
hyperchromasia
(Nuclear morphology)
→
constitutes
→
Object:
nuclear_diagnostic_parameters
(Diagnostic parameters)
Original: Nucleomegaly/ prominent nucleoli/ and hyperchromasia#constitute#current nuclear diagnostic parameters
#3177
low Confidence
Subject:
prominent_nucleoli
(Nuclear morphology)
→
constitutes
→
Object:
nuclear_diagnostic_parameters
(Diagnostic parameters)
Original: Nucleomegaly/ prominent nucleoli/ and hyperchromasia#constitute#current nuclear diagnostic parameters
#3176
low Confidence
Subject:
nucleomegaly
(Nuclear morphology)
→
constitutes
→
Object:
nuclear_diagnostic_parameters
(Diagnostic parameters)
Original: Nucleomegaly/ prominent nucleoli/ and hyperchromasia#constitute#current nuclear diagnostic parameters
#3165
low Confidence
Subject:
fine-needle_aspiration_biopsy_findings
(Fine needle aspiration biopsy results)
→
are_reported_for
→
Object:
sclerosing_hemangioma_of_the_lung
(Tumor type)
Original: Fine-needle aspiration biopsy findings#were reported for#a sclerosing hemangioma of the lung
#3074
low Confidence
Subject:
cells
(cell)
→
display
→
Object:
well_defined_cell_border_and_enlarged_nuclei
(Cell morphology)
Original: cells#had#a well-defined cell border/ scant-to-moderate cytoplasm/ and enlarged vesicular nuclei with prominent nucleoli
#2929
low Confidence
Subject:
molecular_targets
(Molecular targets)
→
provide
→
Object:
diagnostic_strategies_for_thyroid_cancer
(Diagnostic Process)
Original: Molecular targets#could provide#opportunities for diagnostic/ prognostic/ and treatment strategies for thyroid cancer
#2927
low Confidence
Subject:
preoperative_diagnosis
(Diagnosis conclusion)
→
was
→
Object:
pancreatic_carcinoma
(Tumor type)
Original: Preoperative diagnosis#was gastrointestinal carcinoma in#3 cases and pancreatic carcinoma in 1 case
#2926
low Confidence
Subject:
preoperative_diagnosis
(Diagnosis conclusion)
→
was
→
Object:
gastrointestinal_carcinoma
(Tumor type)
Original: Preoperative diagnosis#was gastrointestinal carcinoma in#3 cases and pancreatic carcinoma in 1 case
#2827
low Confidence
Subject:
tumors
(organize)
→
show
→
Object:
clear_cells_endoblastic_pattern
(Organizational Structure)
Original: Tumors#showed#Schiller-Duval body/ endodermal sinus structure/ and clear-cells endoblastic pattern
#2826
low Confidence
Subject:
tumors
(organize)
→
show
→
Object:
endodermal_sinus_structure
(Organizational Structure)
Original: Tumors#showed#Schiller-Duval body/ endodermal sinus structure/ and clear-cells endoblastic pattern
#2825
low Confidence
Subject:
tumors
(organize)
→
show
→
Object:
Schiller_Duval_body
(Organizational Structure)
Original: Tumors#showed#Schiller-Duval body/ endodermal sinus structure/ and clear-cells endoblastic pattern
#2807
low Confidence
Subject:
perinucleolar_region
(Cellular substructure)
→
was_studied_in
→
Object:
lymphocytes
(Immune cells)
Original: Perinucleolar region#was studied in#lymphocytes of chronic B lymphocytic leukemia patients
#2804
low Confidence
Subject:
micronucleoli
(Cell structure)
→
indicate
→
Object:
premature_differentiation_state
(Cellular Processes)
Original: Ring-shaped nucleoli and micronucleoli#indicate#premature differentiation state
#2803
low Confidence
Subject:
ring-shaped_nucleoli
(Cell structure)
→
indicate
→
Object:
premature_differentiation_state
(Cellular Processes)
Original: Ring-shaped nucleoli and micronucleoli#indicate#premature differentiation state
#2765
low Confidence
Subject:
atypical_epithelium
(Histological phenotype)
→
was_observed_in
→
Object:
gastric_biopsies
(Tissue samples)
Original: atypical epithelium#was observed in#gastric biopsies but no diagnosis was confirmed
#2755
low Confidence
Subject:
tumors
(Tumor specimens)
→
were_identified_as
→
Object:
squamous_cell_cancer
(Disease phenotype)
Original: Tumors#were#squamous cell cancer
#2714
low Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizing region)
→
are_examined_in
→
Object:
ameloblastoma
(Disease phenotype)
Original: Nucleolar organizer regions#are examined in#odontogenic cysts and ameloblastomas
#2713
low Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizing region)
→
are_examined_in
→
Object:
odontogenic_cysts
(Disease phenotype)
Original: Nucleolar organizer regions#are examined in#odontogenic cysts and ameloblastomas
#2712
low Confidence
Subject:
nucleolar_size_of_bone_marrow_plasma_cells
(Nucleolus size)
→
has_been_studied_in
→
Object:
bone_marrow_without_M_component
(Disease phenotype)
Original: Nucleolar and nuclear size of bone marrow plasma cells#has been studied in#26 cases of myeloma/ 19 of benign essential monoclonal gammapathy (BEMG)/ and 9 without an M-component
#2711
low Confidence
Subject:
nucleolar_size_of_bone_marrow_plasma_cells
(Nucleolus size)
→
has_been_studied_in
→
Object:
benign_essential_monoclonal_gammapathy
(Disease phenotype)
Original: Nucleolar and nuclear size of bone marrow plasma cells#has been studied in#26 cases of myeloma/ 19 of benign essential monoclonal gammapathy (BEMG)/ and 9 without an M-component
#2710
low Confidence
Subject:
nucleolar_size_of_bone_marrow_plasma_cells
(Nucleolus size)
→
has_been_studied_in
→
Object:
Myeloma
(Disease phenotype)
Original: Nucleolar and nuclear size of bone marrow plasma cells#has been studied in#26 cases of myeloma/ 19 of benign essential monoclonal gammapathy (BEMG)/ and 9 without an M-component
#2637
low Confidence
Subject:
vesicular_nuclei
(Nuclear structure)
→
shows
→
Object:
prominent_nucleoli
(Nucleolus)
Original: cells#contain#vesicular nuclei with 1 to 3 prominent nucleoli
#2636
low Confidence
Subject:
cells
(Cell population)
→
contain
→
Object:
vesicular_nuclei
(Nuclear structure)
Original: cells#contain#vesicular nuclei with 1 to 3 prominent nucleoli
#2634
low Confidence
Subject:
cells
(Cell population)
→
exhibit
→
Object:
multiple_nucleoli
(Nucleolus)
Original: cells#exhibit#multiple nucleoli
#2633
low Confidence
Subject:
nucleoli
(Nucleolus)
→
appear
→
Object:
prominent
(Morphological characteristics)
Original: nucleoli#appear#prominent
#2609
low Confidence
Subject:
Case 3
(patient)
→
had
→
Object:
intermittent episodes of vomiting
(symptom)
Original: case 3#had#intermittent episodes of vomiting
#2608
low Confidence
Subject:
Case 1
(patient)
→
presented_with
→
Object:
falling to the right
(symptom)
Original: case 1#presented with#ataxia/ lethargy/ vomiting/ leaning and falling to the right
#2607
low Confidence
Subject:
Case 1
(patient)
→
presented_with
→
Object:
leaning to the right
(symptom)
Original: case 1#presented with#ataxia/ lethargy/ vomiting/ leaning and falling to the right
#2606
low Confidence
Subject:
Case 1
(patient)
→
presented_with
→
Object:
vomiting
(symptom)
Original: case 1#presented with#ataxia/ lethargy/ vomiting/ leaning and falling to the right
#2605
low Confidence
Subject:
Case 1
(patient)
→
presented_with
→
Object:
lethargy
(symptom)
Original: case 1#presented with#ataxia/ lethargy/ vomiting/ leaning and falling to the right
#2604
low Confidence
Subject:
Case 1
(patient)
→
presented_with
→
Object:
ataxia
(symptom)
Original: case 1#presented with#ataxia/ lethargy/ vomiting/ leaning and falling to the right
#2590
low Confidence
Subject:
AgNOR_technique
(Dyeing technology)
→
was_used_to_study
→
Object:
infiltrating_ductal_breast_carcinoma
(Ductal carcinoma)
Original: AgNOR technique#was used to study#proliferative activity in infiltrating ductal breast carcinoma
#2589
low Confidence
Subject:
AgNOR_technique
(Dyeing technology)
→
was_used_to_study
→
Object:
proliferative_activity
(Cell proliferation)
Original: AgNOR technique#was used to study#proliferative activity in infiltrating ductal breast carcinoma
#2530
low Confidence
Subject:
multicentric_epithelioid_angiosarcoma_of_bone
(Tumor type)
→
is_a_pitfall_in
→
Object:
pathological_diagnosis
(Pathological diagnosis)
Original: Multicentric epithelioid angiosarcoma of the bone#is a pitfall in#pathological diagnoses
#2461
low Confidence
Subject:
fine_needle_aspiration_biopsy_cytology
(Detection Methods)
→
analyzed
→
Object:
renal_oncocytoma
(Tumor type)
Original: fine needle aspiration biopsy cytology#analyzed#renal oncocytoma
#2436
low Confidence
Subject:
Cytologic atypia
(Abnormal cell phenotype)
→
includes
→
Object:
vesicular_chromatin
(Chromatin structure)
Original: Cytologic atypia#includes#nuclear enlargement/ hyperchromasia/ prominent nucleoli/ and vesicular chromatin
#2435
low Confidence
Subject:
Cytologic atypia
(Abnormal cell phenotype)
→
includes
→
Object:
prominent_nucleoli
(Nucleolar morphology)
Original: Cytologic atypia#includes#nuclear enlargement/ hyperchromasia/ prominent nucleoli/ and vesicular chromatin
#2434
low Confidence
Subject:
Cytologic atypia
(Abnormal cell phenotype)
→
includes
→
Object:
hyperchromasia
(Nuclear staining characteristics)
Original: Cytologic atypia#includes#nuclear enlargement/ hyperchromasia/ prominent nucleoli/ and vesicular chromatin
#2433
low Confidence
Subject:
Cytologic atypia
(Abnormal cell phenotype)
→
includes
→
Object:
nuclear_enlargement
(Nuclear morphology)
Original: Cytologic atypia#includes#nuclear enlargement/ hyperchromasia/ prominent nucleoli/ and vesicular chromatin
#2363
low Confidence
Subject:
FNAC_of_extranodal_NHL_of_tongue
(Clinical operation)
→
has_been
→
Object:
rarely_described
(Literature report phenomenon)
Original: FNAC of extranodal NHL of tongue#has rarely been#described
#2340
low Confidence
Subject:
equivocal_diagnoses
(Diagnosis conclusion)
→
were_divided_into
→
Object:
overlap_of_benign_and_malignant_features
(Overlapping benign and malignant features)
Original: Causes of equivocal diagnoses#were divided into#three categories (technical/ inexperience/ overlap of benign and malignant features)
#2339
low Confidence
Subject:
equivocal_diagnoses
(Diagnosis conclusion)
→
were_divided_into
→
Object:
inexperience_category
(Inexperience)
Original: Causes of equivocal diagnoses#were divided into#three categories (technical/ inexperience/ overlap of benign and malignant features)
#2338
low Confidence
Subject:
equivocal_diagnoses
(Diagnosis conclusion)
→
were_divided_into
→
Object:
technical_category
(Technical reasons)
Original: Causes of equivocal diagnoses#were divided into#three categories (technical/ inexperience/ overlap of benign and malignant features)
#2337
low Confidence
Subject:
cells
(cell)
→
were_characterized_by
→
Object:
high_mitotic_rate
(Cell division activity)
Original: cells#were characterized by#prominent nucleoli and high mitotic rate
#2336
low Confidence
Subject:
cells
(cell)
→
were_characterized_by
→
Object:
prominent_nucleoli
(Nucleolar morphology)
Original: cells#were characterized by#prominent nucleoli and high mitotic rate
#2321
low Confidence
Subject:
diffuse_large_B-cell_lymphoma
(Tumor type)
→
imitates
→
Object:
Crohn's_disease
(Inflammatory diseases)
Original: diffuse large B-cell lymphoma#imitates#Crohn's disease
#2298
low Confidence
Subject:
FNA_biopsy
(Fine needle aspiration biopsy)
→
studies
→
Object:
pilomatrixoma_cases
(Case)
Original: Four cases of pilomatrixoma#are studied by#FNA biopsy
#2297
low Confidence
Subject:
patient
(patient)
→
complains_of
→
Object:
nodule
(symptom)
Original: Patient#complains of#a nodule
#2224
low Confidence
Subject:
cytohistologic_findings
(Pathological findings)
→
were_described_in
→
Object:
case_of_metastatic_EP
(Case)
Original: cytohistologic findings#were described in#case of metastatic EP
#2196
low Confidence
Subject:
histological_picture
(Histological characteristics)
→
differs_from
→
Object:
primary_neoplasm
(Primary tumor)
Original: histological picture#differs from#primary neoplasm
#2111
low Confidence
Subject:
tumor_cells
(Tumor cells)
→
ultrastructure_studied_in
→
Object:
AOT_cases
(Clinical Cases)
Original: Ultrastructure of tumour cells and tumour droplets#was studied in#AOT cases
#2090
low Confidence
Subject:
AgNORs
(Silver-stained nucleolar organizing region)
→
are_studied_in
→
Object:
intraepithelial_neoplasia_of_uterine_cervix
(Cervical intraepithelial neoplasia)
Original: nucleolar organizer regions (AgNORs)#are studied in#intraepithelial neoplasia of the uterine cervix
#2089
low Confidence
Subject:
NORs
(Nucleolar organizing region)
→
are_analyzed_in
→
Object:
cervical_intraepithelial_neoplasia
(Cervical intraepithelial neoplasia)
Original: Morphometric study of NORs#was conducted in#cervical intraepithelial neoplasia
#2088
low Confidence
Subject:
NOR-associated_proteins
(Nucleolus-associated protein)
→
are_evaluated_in
→
Object:
malignant_melanoma
(Malignant melanoma)
Original: NOR-associated proteins#were evaluated on#benign and malignant melanocytic skin lesions
#2087
low Confidence
Subject:
NOR-associated_proteins
(Nucleolus-associated protein)
→
are_evaluated_in
→
Object:
benign_melanocytic_lesions
(Benign melanocytic lesions)
Original: NOR-associated proteins#were evaluated on#benign and malignant melanocytic skin lesions
#2079
low Confidence
Subject:
ACA_patterns
(Distribution of nuclear antigens)
→
is_investigated_in
→
Object:
peripheral_blood_cells
(Cell Type)
Original: Silver staining and ACA patterns#are investigated in#bone marrow cells and peripheral blood cells from leukemia patients
#2078
low Confidence
Subject:
ACA_patterns
(Distribution of nuclear antigens)
→
is_investigated_in
→
Object:
bone_marrow_cells
(Cell Type)
Original: Silver staining and ACA patterns#are investigated in#bone marrow cells and peripheral blood cells from leukemia patients
#2077
low Confidence
Subject:
silver_staining
(Analytical techniques)
→
is_investigated_in
→
Object:
peripheral_blood_cells
(Cell Type)
Original: Silver staining and ACA patterns#are investigated in#bone marrow cells and peripheral blood cells from leukemia patients
#2076
low Confidence
Subject:
silver_staining
(Analytical techniques)
→
is_investigated_in
→
Object:
bone_marrow_cells
(Cell Type)
Original: Silver staining and ACA patterns#are investigated in#bone marrow cells and peripheral blood cells from leukemia patients
#2068
low Confidence
Subject:
specimens_from_four_patients
(Clinical samples)
→
were_compared_with
→
Object:
squamous_cell_carcinoma
(Squamous cell carcinoma)
Original: specimens from four patients#were compared with#basal cell carcinoma and squamous cell carcinoma
#2067
low Confidence
Subject:
specimens_from_four_patients
(Clinical samples)
→
were_compared_with
→
Object:
basal_cell_carcinoma
(Basal cell carcinoma)
Original: specimens from four patients#were compared with#basal cell carcinoma and squamous cell carcinoma
#2066
low Confidence
Subject:
Argyrophil_staining
(Silver staining technique)
→
may_be_useful_for
→
Object:
diagnosis_in_cytological_samples
(Cytology sample diagnosis)
Original: Argyrophil staining#may be useful for#diagnosis in small biopsies or cytological samples
#2065
low Confidence
Subject:
Argyrophil_staining
(Silver staining technique)
→
may_be_useful_for
→
Object:
diagnosis_in_small_biopsies
(Small biopsy diagnosis)
Original: Argyrophil staining#may be useful for#diagnosis in small biopsies or cytological samples
#2045
low Confidence
Subject:
cytologic_study_of_cysts
(Cytological analysis)
→
is_valuable_in
→
Object:
diagnosis_of_malignant_processes
(Diagnosis of malignant lesions)
Original: cytologic study of cysts#is valuable in#diagnosis of benign and malignant processes
#2044
low Confidence
Subject:
cytologic_study_of_cysts
(Cytological analysis)
→
is_valuable_in
→
Object:
diagnosis_of_benign_processes
(Diagnosis of benign lesions)
Original: cytologic study of cysts#is valuable in#diagnosis of benign and malignant processes
#1879
low Confidence
Subject:
27-year-old_man
(Patient characteristics)
→
presents_with
→
Object:
instability
(Clinical symptoms)
Original: A 27-year-old man#presented with#nausea/ headaches/ and instability over the last 2 months
#1878
low Confidence
Subject:
27-year-old_man
(Patient characteristics)
→
presents_with
→
Object:
headaches
(Clinical symptoms)
Original: A 27-year-old man#presented with#nausea/ headaches/ and instability over the last 2 months
#1877
low Confidence
Subject:
27-year-old_man
(Patient characteristics)
→
presents_with
→
Object:
nausea
(Clinical symptoms)
Original: A 27-year-old man#presented with#nausea/ headaches/ and instability over the last 2 months
#1871
low Confidence
Subject:
SCNEC_cytologic_features
(Cytological characteristics)
→
include
→
Object:
high_mitotic_karyorrhectic_index
(Cell characteristics)
Original: SCNEC cytologic features#include#hypercellularity/ naked hyperchromatic nuclei/ finely granular nuclear chromatin/ rare nucleoli/ high mitotic karyorrhectic index
#1870
low Confidence
Subject:
SCNEC_cytologic_features
(Cytological characteristics)
→
include
→
Object:
rare_nucleoli
(Cell characteristics)
Original: SCNEC cytologic features#include#hypercellularity/ naked hyperchromatic nuclei/ finely granular nuclear chromatin/ rare nucleoli/ high mitotic karyorrhectic index
#1869
low Confidence
Subject:
SCNEC_cytologic_features
(Cytological characteristics)
→
include
→
Object:
finely_granular_nuclear_chromatin
(Cell characteristics)
Original: SCNEC cytologic features#include#hypercellularity/ naked hyperchromatic nuclei/ finely granular nuclear chromatin/ rare nucleoli/ high mitotic karyorrhectic index
#1868
low Confidence
Subject:
SCNEC_cytologic_features
(Cytological characteristics)
→
include
→
Object:
naked_hyperchromatic_nuclei
(Cell characteristics)
Original: SCNEC cytologic features#include#hypercellularity/ naked hyperchromatic nuclei/ finely granular nuclear chromatin/ rare nucleoli/ high mitotic karyorrhectic index
#1867
low Confidence
Subject:
SCNEC_cytologic_features
(Cytological characteristics)
→
include
→
Object:
hypercellularity
(Cell characteristics)
Original: SCNEC cytologic features#include#hypercellularity/ naked hyperchromatic nuclei/ finely granular nuclear chromatin/ rare nucleoli/ high mitotic karyorrhectic index
#1865
low Confidence
Subject:
morphologic_features
(Morphological characteristics)
→
showed_more_overlap_with
→
Object:
sPRCC
(disease)
Original: morphologic and immunophenotyping features#showed#more overlap between MTSC and sPRCC
#1864
low Confidence
Subject:
morphologic_features
(Morphological characteristics)
→
showed_more_overlap_with
→
Object:
MTSC
(disease)
Original: morphologic and immunophenotyping features#showed#more overlap between MTSC and sPRCC
#1863
low Confidence
Subject:
SCC
(Tumor diseases)
→
was_reviewed_for
→
Object:
cytological_features
(Cytological characteristics)
Original: SCC#was reviewed for#various cytological features
#1853
low Confidence
Subject:
17-year-old_female
(Patient characteristics)
→
was_diagnosed_with
→
Object:
sarcoma_botryoides_of_uterine_cervix
(Tumor diseases)
Original: 17-year-old female#was diagnosed with#sarcoma botryoides of uterine cervix
#1845
low Confidence
Subject:
cytologic_examination
(Cytology)
→
reveals
→
Object:
spindle-shaped_neoplastic_cells
(Tumor cells)
Original: Cytologic examination#reveals#spindle-shaped neoplastic cells with hyperchromatic nuclei and prominent nucleoli
#1706
low Confidence
Subject:
Mean_maximal_nuclear_diameter
(Nuclear morphology parameters)
→
could_not_verify
→
Object:
malignant_follicular_lesion
(Disease phenotype)
Original: Mean maximal nuclear diameter bigger than 7 nm#could not verify#malignant follicular lesion in 8 tumors
#1705
low Confidence
Subject:
histologic_distinction
(Histological features)
→
is_equivocal_between
→
Object:
epidermoid
(Tumor type)
Original: Histologic distinction#is equivocal between#craniopharyngioma and epidermoid
#1704
low Confidence
Subject:
histologic_distinction
(Histological features)
→
is_equivocal_between
→
Object:
craniopharyngioma
(Tumor type)
Original: Histologic distinction#is equivocal between#craniopharyngioma and epidermoid
#1687
low Confidence
Subject:
CT
(Imaging tests)
→
showed
→
Object:
multiple_occupancy
(Structural abnormalities of the spleen)
Original: CT#showed#splenomegaly with multiple occupancy
#1686
low Confidence
Subject:
CT
(Imaging tests)
→
showed
→
Object:
splenomegaly
(Splenic disease phenotype)
Original: CT#showed#splenomegaly with multiple occupancy
#1652
low Confidence
Subject:
cutaneous_mass
(Tumor volume)
→
is_present_in
→
Object:
basal_region_of_auricle
(Anatomical location)
Original: A cutaneous mass#was present in#the basal region of the auricle of a Bichon-Frise dog
#1547
low Confidence
Subject:
physical_examination
(Clinical examination)
→
revealed
→
Object:
absence_of_mass_lesions
(Clinical manifestations)
Original: physical and roentgenographic examinations#revealed#neither lymphadenopathy/ hepatosplenomegaly nor mass lesions
#1546
low Confidence
Subject:
physical_examination
(Clinical examination)
→
revealed
→
Object:
absence_of_hepatosplenomegaly
(Clinical manifestations)
Original: physical and roentgenographic examinations#revealed#neither lymphadenopathy/ hepatosplenomegaly nor mass lesions
#1545
low Confidence
Subject:
physical_examination
(Clinical examination)
→
revealed
→
Object:
absence_of_lymphadenopathy
(Clinical manifestations)
Original: physical and roentgenographic examinations#revealed#neither lymphadenopathy/ hepatosplenomegaly nor mass lesions
#1544
low Confidence
Subject:
nucleoli
(Cell structure)
→
was_not_identified
→
Object:
not_specified
(not_specified)
Original: no cellular atypia/ nuclear inclusions/ mitotic figures/ nor nucleoli#were identified#
#1543
low Confidence
Subject:
mitotic_figures
(Cell division characteristics)
→
was_not_identified
→
Object:
not_specified
(not_specified)
Original: no cellular atypia/ nuclear inclusions/ mitotic figures/ nor nucleoli#were identified#
#1542
low Confidence
Subject:
nuclear_inclusions
(Cell structure)
→
was_not_identified
→
Object:
not_specified
(not_specified)
Original: no cellular atypia/ nuclear inclusions/ mitotic figures/ nor nucleoli#were identified#
#1541
low Confidence
Subject:
cellular_atypia
(Cell morphology)
→
was_not_identified
→
Object:
not_specified
(not_specified)
Original: no cellular atypia/ nuclear inclusions/ mitotic figures/ nor nucleoli#were identified#
#1538
low Confidence
Subject:
case_2
(Case)
→
revealed
→
Object:
peripherally_located_homogeneous_contrast_enhancing_intracranial_mass
(Imaging findings)
Original: case 1 and 2#revealed#peripherally located homogeneous contrast-enhancing intracranial masses
#1537
low Confidence
Subject:
case_1
(Case)
→
revealed
→
Object:
peripherally_located_homogeneous_contrast_enhancing_intracranial_mass
(Imaging findings)
Original: case 1 and 2#revealed#peripherally located homogeneous contrast-enhancing intracranial masses
#1531
low Confidence
Subject:
bulky_pale_gray_vacuolated_cytoplasm
(Cell morphology)
→
distinguishes
→
Object:
latter_from_former
(Organization Type)
Original: bulky pale gray vacuolated cytoplasm#distinguishes#latter from former
#1513
low Confidence
Subject:
tumors
(Tumor tissue)
→
caused
→
Object:
raised_intracranial_pressure
(symptom)
Original: Tumors#caused#absence seizures/ meaningless speech/ hemiparesia/ weight loss/ insufficient breast development/ amenorrhoea/ and raised intracranial pressure
#1512
low Confidence
Subject:
tumors
(Tumor tissue)
→
caused
→
Object:
amenorrhoea
(symptom)
Original: Tumors#caused#absence seizures/ meaningless speech/ hemiparesia/ weight loss/ insufficient breast development/ amenorrhoea/ and raised intracranial pressure
#1511
low Confidence
Subject:
tumors
(Tumor tissue)
→
caused
→
Object:
insufficient_breast_development
(symptom)
Original: Tumors#caused#absence seizures/ meaningless speech/ hemiparesia/ weight loss/ insufficient breast development/ amenorrhoea/ and raised intracranial pressure
#1510
low Confidence
Subject:
tumors
(Tumor tissue)
→
caused
→
Object:
weight_loss
(symptom)
Original: Tumors#caused#absence seizures/ meaningless speech/ hemiparesia/ weight loss/ insufficient breast development/ amenorrhoea/ and raised intracranial pressure
#1509
low Confidence
Subject:
tumors
(Tumor tissue)
→
caused
→
Object:
hemiparesia
(symptom)
Original: Tumors#caused#absence seizures/ meaningless speech/ hemiparesia/ weight loss/ insufficient breast development/ amenorrhoea/ and raised intracranial pressure
#1508
low Confidence
Subject:
tumors
(Tumor tissue)
→
caused
→
Object:
meaningless_speech
(symptom)
Original: Tumors#caused#absence seizures/ meaningless speech/ hemiparesia/ weight loss/ insufficient breast development/ amenorrhoea/ and raised intracranial pressure
#1507
low Confidence
Subject:
tumors
(Tumor tissue)
→
caused
→
Object:
absence_seizures
(symptom)
Original: Tumors#caused#absence seizures/ meaningless speech/ hemiparesia/ weight loss/ insufficient breast development/ amenorrhoea/ and raised intracranial pressure
#1465
low Confidence
Subject:
alkaline_phosphatase_activity
(Enzyme activity)
→
is_weakly_positive_in
→
Object:
Cytoplasm
(Cellular substructure)
Original: alkaline phosphatase activity#is weakly positive in#cytoplasm
#1426
low Confidence
Subject:
histological_features
(Histological characteristics)
→
encompass
→
Object:
atypical_Spitz_tumor
(Tumor phenotype)
Original: histological features#encompass#a range from Spitz nevus to atypical Spitz tumor
#1425
low Confidence
Subject:
histological_features
(Histological characteristics)
→
encompass
→
Object:
Spitz_nevus
(Benign tumors)
Original: histological features#encompass#a range from Spitz nevus to atypical Spitz tumor
#1291
low Confidence
Subject:
Tumor_cells
(Tumor cells)
→
showed
→
Object:
abortive_biliary_differentiation
(Differentiation phenotype)
Original: Tumor cells#showed#absent nucleoli and abortive biliary differentiation
#1290
low Confidence
Subject:
Tumor_cells
(Tumor cells)
→
showed
→
Object:
absent_nucleoli
(Cell morphology)
Original: Tumor cells#showed#absent nucleoli and abortive biliary differentiation
#1251
low Confidence
Subject:
polyclonal_antibody_directed_against_neuron-specific_enolase
(Polyclonal antibodies)
→
shows
→
Object:
equivocal_staining
(Immunostaining results)
Original: Polyclonal antibody directed against neuron-specific enolase#shows#equivocal staining
#1117
low Confidence
Subject:
mitotic_figures
(Cell division figures)
→
were_found_in
→
Object:
high-power_fields
(Pathological observation conditions)
Original: mitotic figures#were found in#high-power fields
#1116
low Confidence
Subject:
4-year-old_boy
(Patient characteristics)
→
presented_with
→
Object:
tracheal_obstruction_symptoms
(Clinical symptoms)
Original: 4-year-old boy#presented with#symptoms of tracheal obstruction
#1115
low Confidence
Subject:
malignancy
(Disease phenotype)
→
was_suspected_in
→
Object:
patient
(patient)
Original: Malignancy#was suspected in#the patient
#1085
low Confidence
Subject:
pleural_needle_biopsy
(Histological procedures)
→
demonstrated
→
Object:
solid_uniform_tumor_cells
(Cytological characteristics)
Original: pleural needle biopsy#demonstrated#solid uniform tumor cells
#1084
low Confidence
Subject:
hypoechoic_right_breast_mass
(Tumor imaging findings)
→
revealed
→
Object:
solid_nests_of_small_monotonous_tumor_cells
(Histological characteristics)
Original: hypoechoic right breast mass#revealed#solid nests of small monotonous tumor cells
#859
low Confidence
Subject:
fine-needle_aspiration_cytology
(Cytology)
→
was_performed_for
→
Object:
metastatic_eccrine_porocarcinoma
(Tumor diseases)
Original: fine-needle aspiration cytology#was performed for#metastatic eccrine porocarcinoma
#662
low Confidence
Subject:
single-core_localization
(Cellular substructure)
→
is_present_in
→
Object:
foamy_gland_carcinoma
(Tumor type)
Original: Single-core localization#is present in#7 of 14 pure foamy gland carcinomas
#633
low Confidence
Subject:
mean_AgNOR_counts
(AgNOR Count)
→
indicate
→
Object:
diagnostic_value
(Diagnostic value)
Original: mean AgNOR counts for odontogenic cysts and ameloblastomas#indicate#neither diagnostic nor prognostic value
#620
low Confidence
Subject:
69_year_old_male_patient
(Patient characteristics)
→
presents_with
→
Object:
weight_loss
(Clinical symptoms)
Original: 69-year-old male patient#presented with#abdominal mass/ intestinal transit disorder/ and weight loss
#619
low Confidence
Subject:
69_year_old_male_patient
(Patient characteristics)
→
presents_with
→
Object:
intestinal_transit_disorder
(Clinical symptoms)
Original: 69-year-old male patient#presented with#abdominal mass/ intestinal transit disorder/ and weight loss
#618
low Confidence
Subject:
69_year_old_male_patient
(Patient characteristics)
→
presents_with
→
Object:
abdominal_mass
(Clinical symptoms)
Original: 69-year-old male patient#presented with#abdominal mass/ intestinal transit disorder/ and weight loss
#603
low Confidence
Subject:
fine_needle_aspiration_diagnosis
(Clinical diagnostic technology)
→
has_not_been_reported_for
→
Object:
adenoid_cystic_carcinoma_of_external_auditory_canal
(Tumor)
Original: fine needle aspiration diagnosis#has not been reported#for adenoid cystic carcinoma of the external auditory canal in English-language literature
#558
low Confidence
Subject:
preoperative_diagnosis
(Diagnostic Process)
→
is_difficult_for
→
Object:
papillary_renal_cell_carcinoma
(disease)
Original: Preoperative diagnosis#is difficult for#renal calculus complicated with papillary renal cell carcinoma (RCC)
#557
low Confidence
Subject:
preoperative_diagnosis
(Diagnostic Process)
→
is_difficult_for
→
Object:
renal_calculus
(disease)
Original: Preoperative diagnosis#is difficult for#renal calculus complicated with papillary renal cell carcinoma (RCC)
#537
low Confidence
Subject:
AgNOR_staining_technique
(Dyeing technology)
→
was_studied_in
→
Object:
malignant_salivary_gland_lesions
(Malignant glandular lesions)
Original: Ag-NOR staining technique#was studied in#benign and malignant salivary gland lesions
#536
low Confidence
Subject:
AgNOR_staining_technique
(Dyeing technology)
→
was_studied_in
→
Object:
benign_salivary_gland_lesions
(Benign glandular lesions)
Original: Ag-NOR staining technique#was studied in#benign and malignant salivary gland lesions
#528
low Confidence
Subject:
inguinal_sentinel_node
(Lymph nodes)
→
biopsy_was_performed
→
Object:
not_specified
(not_specified)
Original: Knee and perianal lesions#were resected and#inguinal sentinel node biopsy was performed
#517
low Confidence
Subject:
lymph_node
(organize)
→
exhibits
→
Object:
swelling
(Organizational characteristics)
Original: CT scan#showed#swollen lymph nodes and a huge abdominal mass
#504
low Confidence
Subject:
metastatic_lesions
(Tumor metastasis)
→
are_not_found
→
Object:
current_time_point
(Time conditions)
Original: metastatic lesions#are not found#now
#483
low Confidence
Subject:
67_year_old_man
(Patient characteristics)
→
presents_with
→
Object:
melaena
(Clinical symptoms)
Original: 67-year-old man#presents with#weight loss/ intermittent severe abdominal pain/ and melaena
#482
low Confidence
Subject:
67_year_old_man
(Patient characteristics)
→
presents_with
→
Object:
severe_abdominal_pain
(Clinical symptoms)
Original: 67-year-old man#presents with#weight loss/ intermittent severe abdominal pain/ and melaena
#481
low Confidence
Subject:
67_year_old_man
(Patient characteristics)
→
presents_with
→
Object:
weight_loss
(Clinical symptoms)
Original: 67-year-old man#presents with#weight loss/ intermittent severe abdominal pain/ and melaena
#461
low Confidence
Subject:
tumor
(Tumor type)
→
presents_as
→
Object:
pelvic_mass
(Clinical symptoms)
Original: tumors#presented as#a pelvic mass posthysterectomy in 1 case
#401
low Confidence
Subject:
cytological_features
(Cytological characteristics)
→
were_evaluated_for
→
Object:
nucleoli
(Nucleolar characteristics)
Original: Cytological features#were evaluated for#cellularity/ pleomorphism/ N/C ratio/ chromatin pattern/ nucleoli/ macrophages/ multinucleated giant cells/ and mitosis
#400
low Confidence
Subject:
cytological_features
(Cytological characteristics)
→
were_evaluated_for
→
Object:
Pleomorphism
(Cell morphology)
Original: Cytological features#were evaluated for#cellularity/ pleomorphism/ N/C ratio/ chromatin pattern/ nucleoli/ macrophages/ multinucleated giant cells/ and mitosis
#393
low Confidence
Subject:
Fine-needle_aspirates
(Collection method)
→
revealed
→
Object:
dispersed_cell_population
(Cell population)
Original: Fine-needle aspirates#revealed#a dispersed cell population with occasional clustering
#312
low Confidence
Subject:
painless_lump
(Clinical phenotype)
→
was_gradually_enlarging
→
Object:
not_specified
(not_specified)
Original: 24-year-old woman#presented with#a gradually enlarging/ painless lump in the left side of the face
#311
low Confidence
Subject:
24-year-old_woman
(patient)
→
presented_with
→
Object:
left_facial_location
(Anatomical location)
Original: 24-year-old woman#presented with#a gradually enlarging/ painless lump in the left side of the face
#310
low Confidence
Subject:
24-year-old_woman
(patient)
→
presented_with
→
Object:
painless_lump
(Clinical phenotype)
Original: 24-year-old woman#presented with#a gradually enlarging/ painless lump in the left side of the face
#303
low Confidence
Subject:
chromogranin_A
(Protein markers)
→
may_be_helpful_in
→
Object:
small_biopsy_specimens
(Sample Type)
Original: immunohistochemistry for CEA/ LCA/ and chromogranin A#may be helpful in#small biopsy specimens
#302
low Confidence
Subject:
LCA
(Protein markers)
→
may_be_helpful_in
→
Object:
small_biopsy_specimens
(Sample Type)
Original: immunohistochemistry for CEA/ LCA/ and chromogranin A#may be helpful in#small biopsy specimens
#301
low Confidence
Subject:
CEA
(Protein markers)
→
may_be_helpful_in
→
Object:
small_biopsy_specimens
(Sample Type)
Original: immunohistochemistry for CEA/ LCA/ and chromogranin A#may be helpful in#small biopsy specimens
#300
low Confidence
Subject:
tumor
(Tumor tissue)
→
did_not_produce
→
Object:
neutral_mucin
(Secretions)
Original: no tumor#produced#neutral mucin
#299
low Confidence
Subject:
nuclei
(Nucleus)
→
had
→
Object:
open_appearance_with_prominent_nucleoli_and_delicate_chromatin
(Nuclear structural characteristics)
Original: nuclei#had#a particularly characteristic open appearance with prominent nucleoli and delicate chromatin
#298
low Confidence
Subject:
tumors
(Tumor tissue)
→
did_not_show
→
Object:
haematoxyphilic_blood_vessels
(Organizational form)
Original: tumors#did not show#streams/ ribbons/ rosettes/ or haematoxyphilic blood vessels typical of small cell carcinoma
#297
low Confidence
Subject:
tumors
(Tumor tissue)
→
did_not_show
→
Object:
rosettes
(Organizational form)
Original: tumors#did not show#streams/ ribbons/ rosettes/ or haematoxyphilic blood vessels typical of small cell carcinoma
#296
low Confidence
Subject:
tumors
(Tumor tissue)
→
did_not_show
→
Object:
ribbons
(Organizational form)
Original: tumors#did not show#streams/ ribbons/ rosettes/ or haematoxyphilic blood vessels typical of small cell carcinoma
#295
low Confidence
Subject:
tumors
(Tumor tissue)
→
did_not_show
→
Object:
streams
(Organizational form)
Original: tumors#did not show#streams/ ribbons/ rosettes/ or haematoxyphilic blood vessels typical of small cell carcinoma
#292
low Confidence
Subject:
72-year-old_man
(patient)
→
presented_with
→
Object:
high_right_heart_load
(Clinical phenotype)
Original: 72-year-old man#presented with#chronic atrial fibrillation and high right heart load
#291
low Confidence
Subject:
72-year-old_man
(patient)
→
presented_with
→
Object:
chronic_atrial_fibrillation
(disease)
Original: 72-year-old man#presented with#chronic atrial fibrillation and high right heart load
#237
low Confidence
Subject:
intestinal_metaplasia_type
(Intestinal metaplasia type)
→
is_compared_in
→
Object:
gastric_carcinoma
(disease)
Original: Gastric carcinoma biopsy specimens#compared for#abnormal histologic features/ type of intestinal metaplasia/ and presence of CEA
#236
low Confidence
Subject:
histologic_feature
(Histological characteristics)
→
is_compared_in
→
Object:
gastric_carcinoma
(disease)
Original: Gastric carcinoma biopsy specimens#compared for#abnormal histologic features/ type of intestinal metaplasia/ and presence of CEA
#204
low Confidence
Subject:
case
(Case)
→
might_be_mistaken_with
→
Object:
Hodgkin's_lymphoma
(Tumor type)
Original: case#might be mistaken with#a Hodgkin's lymphoma
#128
low Confidence
Subject:
no_diagnosis
(Diagnosis conclusion)
→
was_confirmed
→
Object:
gastric_biopsies
(Tissue samples)
Original: atypical epithelium#was observed in#gastric biopsies but no diagnosis was confirmed
#110
low Confidence
Subject:
fine_needle_aspiration_cytology
(Clinical diagnostic technology)
→
was_performed
→
Object:
not_specified
(not_specified)
Original: fine needle aspiration cytology#was performed#
#106
low Confidence
Subject:
Cytological_literature
(Documentary evidence)
→
is_scarce_on
→
Object:
sarcomatoid_carcinoma_in_voided_urine
(Disease phenotype)
Original: Cytological literature#is scarce on#sarcomatoid carcinoma in voided urine
#81
low Confidence
Subject:
ovarian_granulosa_cell_tumor
(Tumor type)
→
are_discussed
→
Object:
differential_aspects
(Diagnostic features)
Original: testicular and ovarian granulosa cell tumors#are discussed#differential aspects
#80
low Confidence
Subject:
testicular_granulosa_cell_tumor
(Tumor type)
→
are_discussed
→
Object:
differential_aspects
(Diagnostic features)
Original: testicular and ovarian granulosa cell tumors#are discussed#differential aspects
#79
low Confidence
Subject:
AgNOR_counting
(Molecular detection methods)
→
cannot_reliably_differentiate
→
Object:
carcinoma
(Malignant tumors)
Original: AgNOR counting#cannot reliably differentiate#adenoma from carcinoma on an individual case basis
#78
low Confidence
Subject:
AgNOR_counting
(Molecular detection methods)
→
cannot_reliably_differentiate
→
Object:
adenoma
(Benign tumors)
Original: AgNOR counting#cannot reliably differentiate#adenoma from carcinoma on an individual case basis
#17
low Confidence
Subject:
tumor
(Tumor)
→
is_considered_as
→
Object:
benign_lesion
(Benign lesions)
Original: Tumors#are considered as#a benign lesion