临床相关性：Transcriptional regulation
A total of 9 records found
#19206
middle Confidence
Subject:
DEPDC1B
(Protein coding genes)
→
is_direct_target_of
→
Object:
B-Myb
(Transcription Factors)
Original: DEPDC1B#is a direct target of#B-Myb
#19196
middle Confidence
Subject:
histone_deacetylase
(Enzymes)
→
silences
→
Object:
nucleolar_gene_transcription
(Transcription process)
Original: MTG16a protein#interacts with#histone deacetylases (HDACs) to silence nucleolar gene transcription
#19187
middle Confidence
Subject:
MDM2
(protein)
→
is_necessary_for
→
Object:
transcription_inhibition
(Transcriptional regulation)
Original: Interaction with p53 and transcription inhibition#are necessary for#MDM2 function
#17196
middle Confidence
Subject:
MTG16a_protein
(Transcriptional regulatory proteins)
→
interacts_with
→
Object:
histone_deacetylase
(Enzymes)
Original: MTG16a protein#interacts with#histone deacetylases (HDACs) to silence nucleolar gene transcription
#17124
middle Confidence
Subject:
SLERT
(Long noncoding RNA)
→
regulates
→
Object:
Pol_I_transcription
(Transcription process)
Original: SLERT#regulates#DDX21 rings associated with Pol I transcription
#17075
middle Confidence
Subject:
DHX33_K94R_mutant
(DEAD/DEAH-box helicase mutants)
→
inhibits
→
Object:
endogenous_rRNA_synthesis
(rRNA synthesis)
Original: NTPase-defective DHX33 mutant (K94R)#inhibited#endogenous rRNA synthesis
#17074
middle Confidence
Subject:
DHX33
(DEAD/DEAH-box helicase)
→
overexpression_enhances
→
Object:
47S_rRNA_synthesis
(rRNA synthesis)
Original: Wild-type DHX33 overexpression#enhanced#47S rRNA synthesis
#17073
middle Confidence
Subject:
DHX33
(DEAD/DEAH-box helicase)
→
knockdown_decreases
→
Object:
rRNA_synthesis
(rRNA synthesis)
Original: DHX33 knockdown#decreased#association of Pol I with rDNA and rRNA synthesis
#17072
middle Confidence
Subject:
DHX33
(DEAD/DEAH-box helicase)
→
knockdown_decreases
→
Object:
Pol_I_association_with_rDNA
(Molecular complex)
Original: DHX33 knockdown#decreased#association of Pol I with rDNA and rRNA synthesis