Search results of triples

A total of 33 records found

#21652 high Confidence
Subject: NPM1 (Nucleolar proteins)
facilitates
Object: ribosome_biogenesis (Molecular complex synthesis)
Original: NPM1#facilitates#ribosome biogenesis and nucleolar stress responses
🏥 not_specified 🧬 NPM1 📄 PMID: 39528457
#21520 high Confidence
Subject: chemotherapeutic_effects (Chemotherapy effect)
were_assessed_using
Object: nucleolar_presence (Nucleolus exists)
Original: Recurrent neoplasm and chemotherapeutic effects#were assessed using#nucleolar presence and other criteria
🏥 Evaluation of treatment response 📄 PMID: 10485547
#21519 high Confidence
Subject: recurrent_neoplasm (Recurrent tumors)
were_assessed_using
Object: nucleolar_presence (Nucleolus exists)
Original: Recurrent neoplasm and chemotherapeutic effects#were assessed using#nucleolar presence and other criteria
🏥 Evaluation of treatment response 📄 PMID: 10485547
#20092 high Confidence
Subject: Nucleophosmin_1 (Nucleolar proteins)
regulates
Object: ribosome_biogenesis (Cellular Processes)
Original: Nucleophosmin 1 (NPM1)#regulates#centrosome duplication/ ribosome biogenesis and export/ histone assembly/ genomic stability/ and nucleolar stress response
🏥 not_specified 🧬 NPM1 📄 PMID: 36008542
#20091 high Confidence
Subject: Nucleophosmin_1 (Nucleolar proteins)
regulates
Object: centrosome_duplication (Cellular Processes)
Original: Nucleophosmin 1 (NPM1)#regulates#centrosome duplication/ ribosome biogenesis and export/ histone assembly/ genomic stability/ and nucleolar stress response
🏥 not_specified 🧬 NPM1 📄 PMID: 36008542
#20000 high Confidence
Subject: Nucleophosmin_1 (Nucleolar proteins)
regulates
Object: nucleolar_stress_response (Cellular Processes)
Original: Nucleophosmin 1 (NPM1)#regulates#centrosome duplication/ ribosome biogenesis and export/ histone assembly/ genomic stability/ and nucleolar stress response
🏥 not_specified 🧬 NPM1 📄 PMID: 36008542
#19918 middle Confidence
Subject: NPM1 (Nucleolar proteins)
facilitates
Object: nucleolar_stress_response (Cellular stress response)
Original: NPM1#facilitates#ribosome biogenesis and nucleolar stress responses
🏥 not_specified 🧬 NPM1 📄 PMID: 39528457
#19882 middle Confidence
Subject: ribosomal_proteins (Ribosomal proteins)
play_important_role_in
Object: p53_activation_in_response_to_nucleolar_stress (Stress response)
Original: Ribosomal proteins#play an important role in#p53 activation in response to nucleolar stress
🏥 not_specified 🧬 TP53 📄 PMID: 20554519
#18983 middle Confidence
Subject: cytostatics (Chemotherapy drugs)
induce
Object: nucleolar_phenotype_changes (Cell phenotype changes)
Original: Cytostatics-induced changes of nucleolar phenotype#point to#a potential role of nucleolar components in the execution of active cell death
🏥 Cellular stress response 📄 PMID: 12485873
#17079 middle Confidence
Subject: ribosomal_proteins (Ribosomal proteins)
control
Object: tumor_suppressor_pathways (signaling pathway)
Original: Ribosomal proteins#control#tumor suppressor pathways in response to nucleolar stress
🏥 not_specified 📄 PMID: 30706966
#16976 middle Confidence
Subject: nucleolar_morphology (Cell structure characteristics)
is_linked_to
Object: stress_responses (Cellular stress response)
Original: Alterations in nucleolar morphology and protein content#are linked to#control of cell proliferation and stress responses
🏥 not_specified 📄 PMID: 30988155
#16975 middle Confidence
Subject: nucleolar_morphology (Cell structure characteristics)
is_linked_to
Object: control_of_cell_proliferation (Cellular Processes)
Original: Alterations in nucleolar morphology and protein content#are linked to#control of cell proliferation and stress responses
🏥 not_specified 📄 PMID: 30988155
#16900 middle Confidence
Subject: p14 (protein)
regulates
Object: p53_stabilization (Protein stability)
Original: p14#regulates#nucleolar stress response/ ribosome biogenesis/ and p53 stabilization
🏥 not_specified 🧬 TP53 📄 PMID: 36366533
#16899 middle Confidence
Subject: p14 (protein)
regulates
Object: ribosome_biogenesis (Ribosome biogenesis)
Original: p14#regulates#nucleolar stress response/ ribosome biogenesis/ and p53 stabilization
🏥 not_specified 🧬 TP53 📄 PMID: 36366533
#16898 middle Confidence
Subject: p14 (protein)
regulates
Object: nucleolar_stress_response (Cellular stress process)
Original: p14#regulates#nucleolar stress response/ ribosome biogenesis/ and p53 stabilization
🏥 not_specified 🧬 TP53 📄 PMID: 36366533
#16851 middle Confidence
Subject: ribosomal_proteins (Ribosomal proteins)
mediate
Object: p53_activation (Transcription factor activation)
Original: Ribosomal proteins#mediate#p53 activation in response to nucleolar disruption
🏥 not_specified 🧬 TP53 📄 PMID: 19713960
#16711 middle Confidence
Subject: berberine (Small molecule drugs)
causes
Object: nucleolar_stress_response (Molecular stress response)
Original: berberine#caused#nucleolar stress response
🏥 not_specified 🧬 TP53 📄 PMID: 32475643
#16553 middle Confidence
Subject: first_fraction_of_radiotherapy (Treatment Process)
induces_changes_in
Object: AgNORs (Molecular modification)
Original: First fraction of radiotherapy protocol#induces changes in#silver-stained nucleolar organizer regions (AgNORs)
🏥 Response to treatment 📄 PMID: 11917578
#12493 middle Confidence
Subject: nucleolar_stress (Cellular stress)
activates
Object: JNK (Mitogen-activated protein kinase)
Original: Nucleolar stress#activated#Jun N-terminal kinase (JNK) in Nopp140-depleted larvae
🏥 Stress response 🧬 MAPK8 📄 PMID: 23412656
#12399 middle Confidence
Subject: subnucleolar_compartment (Subcellular structure)
changes_in_morphology_in_response_to
Object: transcription_level (Molecular modification regulation)
Original: Protein composition and morphology of subnucleolar compartments#change in response to#transcription and phosphorylation levels and during mitosis
🏥 not_specified 📄 PMID: 12839096
#12357 middle Confidence
Subject: NuMA (Cytoskeletal proteins)
supports
Object: central_role_in_rDNA_transcription (rDNA transcription regulation)
Original: NuMA#supports#a central role in rDNA transcription and p53-independent nucleolar stress response
🏥 not_specified 🧬 NUMA1 📄 PMID: 28981686
#12355 middle Confidence
Subject: NuMA (Cytoskeletal proteins)
is_involved_in
Object: p53-mediated_growth_arrest (Cell cycle arrest)
Original: NuMA#is involved in#DNA damage response/ apoptosis/ and p53-mediated growth arrest under nucleolar stress
🏥 not_specified 🧬 NUMA1 📄 PMID: 28981686
#12354 middle Confidence
Subject: NuMA (Cytoskeletal proteins)
is_involved_in
Object: apoptosis (Apoptosis)
Original: NuMA#is involved in#DNA damage response/ apoptosis/ and p53-mediated growth arrest under nucleolar stress
🏥 not_specified 🧬 NUMA1 📄 PMID: 28981686
#12353 middle Confidence
Subject: NuMA (Cytoskeletal proteins)
is_involved_in
Object: DNA_damage_response (Cellular stress response)
Original: NuMA#is involved in#DNA damage response/ apoptosis/ and p53-mediated growth arrest under nucleolar stress
🏥 not_specified 🧬 NUMA1 📄 PMID: 28981686
#12199 middle Confidence
Subject: PPAN (Ribosome biogenesis regulatory protein)
defines
Object: p53_independent_nucleolar_stress_response_pathway (Stress Pathway)
Original: Wnt Target Protein Peter Pan#defines#a novel p53-independent nucleolar stress-response pathway
🏥 Stress response 📄 PMID: 25759387
#12000 middle Confidence
Subject: DNA_damage_response (Cellular Processes)
triggers
Object: nucleolar_and_ribosomal_stress (Molecular stress response)
Original: DNA damage response#triggered#nucleolar and ribosomal stress
🏥 not_specified 📄 PMID: 28478306
#11729 middle Confidence
Subject: first_fraction_of_radiotherapy (Treatment Process)
induces_changes_in
Object: gynecologic_cancer (Tumor type)
Original: First fraction of radiotherapy protocol#induces changes in#silver-stained nucleolar organizer regions (AgNORs)
🏥 Response to treatment 📄 PMID: 11917578
#10743 middle Confidence
Subject: subnucleolar_compartment (Subcellular structure)
changes_in_morphology_during
Object: Mitosis (Cellular Processes)
Original: Protein composition and morphology of subnucleolar compartments#change in response to#transcription and phosphorylation levels and during mitosis
🏥 not_specified 📄 PMID: 12839096
#10742 middle Confidence
Subject: subnucleolar_compartment (Subcellular structure)
changes_in_morphology_in_response_to
Object: phosphorylation_level (Molecular modification regulation)
Original: Protein composition and morphology of subnucleolar compartments#change in response to#transcription and phosphorylation levels and during mitosis
🏥 not_specified 📄 PMID: 12839096
#10736 middle Confidence
Subject: p53-independent_pathway (signaling pathway)
regulates
Object: antigen_translocation (Subcellular structure process)
Original: p53-independent pathway#regulates#nucleolar segregation and antigen translocation in response to DNA damage
🏥 not_specified 🧬 TP53 📄 PMID: 14720517
#10735 middle Confidence
Subject: p53-independent_pathway (signaling pathway)
regulates
Object: nucleolar_segregation (Subcellular structure process)
Original: p53-independent pathway#regulates#nucleolar segregation and antigen translocation in response to DNA damage
🏥 not_specified 🧬 TP53 📄 PMID: 14720517
#6484 middle Confidence
Subject: NuMA (Cytoskeletal proteins)
supports
Object: p53-independent_nucleolar_stress_response (Cellular stress response)
Original: NuMA#supports#a central role in rDNA transcription and p53-independent nucleolar stress response
🏥 not_specified 🧬 NUMA1 📄 PMID: 28981686
#105 low Confidence
Subject: PPAN (Ribosome biogenesis-associated protein)
function_unknown
Object: nucleolar_stress_response (Cellular stress response)
Original: The role of PPAN in nucleolar stress response#has remained#elusive
🏥 not_specified 🧬 PPAN 📄 PMID: 25759387