List of serched triples

A total of 22252 records found

#19112 middle Confidence
Subject: nucleolus (Cellular substructure)
functions_as
Object: center_of_metabolic_control (Metabolic Regulation Center)
Original: The nucleolus#is deemed#the center of metabolic control
🏥 not_specified 📄 PMID: 29725012
#19111 middle Confidence
Subject: nucleolar_disruption (Organelle dysfunction)
induces
Object: accumulation_of_p53 (Protein stability regulation)
Original: Nucleolar disruption#induces#acetylation and accumulation of p53
🏥 not_specified 🧬 TP53 📄 PMID: 21297583
#19110 middle Confidence
Subject: nucleolar_disruption (Organelle dysfunction)
induces
Object: acetylation_of_p53 (Protein modification events)
Original: Nucleolar disruption#induces#acetylation and accumulation of p53
🏥 not_specified 🧬 TP53 📄 PMID: 21297583
#19109 middle Confidence
Subject: pKi-67 (Phosphorylated proteins)
functions_in
Object: ribosomal_RNA_synthesis_initiation (Initiation of rRNA synthesis)
Original: pKi-67#functions in#early steps of ribosomal RNA synthesis
🏥 not_specified 🧬 MKI67 📄 PMID: 17531085
#19108 middle Confidence
Subject: nucleoli (Nuclear structure)
orchestrate
Object: cell_response_to_stress_signals (Cellular stress response)
Original: Nucleoli#orchestrate#cell response to stress signals
🏥 not_specified 📄 PMID: 16205120
#19107 middle Confidence
Subject: MYBBP1A (Nucleoprotein)
induces
Object: p53_accumulation (Protein accumulation)
Original: Translocated MYBBP1A#induces#acetylation and accumulation of p53
🏥 not_specified 🧬 MYBBP1A/TP53 📄 PMID: 21471221
#19106 middle Confidence
Subject: MYBBP1A (Nucleoprotein)
induces
Object: p53_acetylation (Protein modification)
Original: Translocated MYBBP1A#induces#acetylation and accumulation of p53
🏥 not_specified 🧬 MYBBP1A/TP53 📄 PMID: 21471221
#19105 middle Confidence
Subject: CDKN2A (Cell cycle inhibitors)
plays_role_in
Object: oncogenic_surveillance (Tumor surveillance)
Original: ARF#plays a role in#surveillance of oncogenic insults
🏥 Tumor suppressor mechanisms 🧬 CDKN2A 📄 PMID: 14636574
#19104 middle Confidence
Subject: PML (protein)
plays_role_in
Object: nucleolar_network_for_tumor_suppression (Molecular complex)
Original: PML#plays a role in#nucleolar network for tumour suppression
🏥 Tumor suppressor mechanisms 🧬 PML 📄 PMID: 15195100
#19103 middle Confidence
Subject: PML_nucleolar_localization (Protein localization)
is_dependent_on
Object: ATR_activation (Protein kinase activation)
Original: Nucleolar localization of PML#is dependent on#ATR activation
🏥 not_specified 🧬 PML/ATR 📄 PMID: 15195100
#19102 middle Confidence
Subject: GSK3B (Protein kinase)
inhibition_upregulates
Object: 28S_rRNA_synthesis (Ribosomal RNA synthesis)
Original: GSK3beta inhibition#upregulated#45S/ 18S and 28S rRNA synthesis
🏥 not_specified 🧬 GSK3B 📄 PMID: 18490923
#19101 middle Confidence
Subject: GSK3B (Protein kinase)
inhibition_upregulates
Object: 18S_rRNA_synthesis (Ribosomal RNA synthesis)
Original: GSK3beta inhibition#upregulated#45S/ 18S and 28S rRNA synthesis
🏥 not_specified 🧬 GSK3B 📄 PMID: 18490923
#19100 middle Confidence
Subject: GSK3B (Protein kinase)
inhibition_upregulates
Object: 45S_rRNA_synthesis (Ribosomal RNA synthesis)
Original: GSK3beta inhibition#upregulated#45S/ 18S and 28S rRNA synthesis
🏥 not_specified 🧬 GSK3B 📄 PMID: 18490923
#19099 middle Confidence
Subject: GLTSCR2 (Protein coding genes)
regulates
Object: TP53 (Protein coding genes)
Original: GLTSCR2#regulates#two major tumor suppressor proteins/ PTEN and p53
🏥 not_specified 🧬 GLTSCR2/PTEN/TP53 📄 PMID: 22292050
#19098 middle Confidence
Subject: GLTSCR2 (Protein coding genes)
regulates
Object: PTEN (Protein coding genes)
Original: GLTSCR2#regulates#two major tumor suppressor proteins/ PTEN and p53
🏥 not_specified 🧬 GLTSCR2/PTEN/TP53 📄 PMID: 22292050
#19097 middle Confidence
Subject: nucleoli_number (Nuclear structure)
is_used_as
Object: prognostic_tool_for_tumor_proliferation (Clinical Tools)
Original: Increased number of nucleoli#is used as#prognostic tools to evaluate tumor proliferation levels
🏥 Prognosis 📄 PMID: 15811115
#19096 middle Confidence
Subject: MMP2 (Protease)
reduces
Object: cell_proliferation (Cellular Processes)
Original: Knocking down/out matrix metalloproteinase-2#reduces#cell proliferation
🏥 not_specified 🧬 MMP2 📄 PMID: 34101354
#19095 middle Confidence
Subject: MMP2 (Protease)
reduces
Object: ribosomal_RNA_transcription (Transcription process)
Original: Knocking down/out matrix metalloproteinase-2#reduces#ribosomal RNA transcription
🏥 not_specified 🧬 MMP2 📄 PMID: 34101354
#19094 middle Confidence
Subject: MMP2 (Protease)
prevents
Object: histone_H3_cleavage (Protein modification events)
Original: Knocking down/out matrix metalloproteinase-2#prevents#histone H3 cleavage
🏥 not_specified 🧬 MMP2 📄 PMID: 34101354
#19093 middle Confidence
Subject: Hernandonine (Small molecule compounds)
induces
Object: cellular_apoptosis (Apoptosis)
Original: Hernandonine#induces#cellular apoptosis in solid tumor cell lines
🏥 Therapeutic significance 📄 PMID: 31409627