List of serched triples

A total of 22252 records found

#16832 middle Confidence
Subject: active_GSK3B_mutant (Protein kinase mutants)
abolishes
Object: nucleolar_BrUTP_incorporation (Nucleolar RNA synthesis markers)
Original: Active GSK3beta mutant#abolished#nucleolar BrUTP incorporation
🏥 not_specified 🧬 GSK3B 📄 PMID: 18490923
#16831 middle Confidence
Subject: tumor_suppressors (Tumor suppressor proteins)
interfere_with
Object: rRNA_synthesis (rRNA synthesis)
Original: Oncogenic proteins and tumor suppressors#target#RNA polymerase I and interfere with rRNA synthesis
🏥 Tumorigenesis 📄 PMID: 18490923
#16830 middle Confidence
Subject: oncogenic_proteins (Oncogenic proteins)
interfere_with
Object: rRNA_synthesis (rRNA synthesis)
Original: Oncogenic proteins and tumor suppressors#target#RNA polymerase I and interfere with rRNA synthesis
🏥 Tumorigenesis 📄 PMID: 18490923
#16829 middle Confidence
Subject: tumor_suppressors (Tumor suppressor proteins)
target
Object: RNA_polymerase_I (Transcriptase)
Original: Oncogenic proteins and tumor suppressors#target#RNA polymerase I and interfere with rRNA synthesis
🏥 Tumorigenesis 📄 PMID: 18490923
#16828 middle Confidence
Subject: oncogenic_proteins (Oncogenic proteins)
target
Object: RNA_polymerase_I (Transcriptase)
Original: Oncogenic proteins and tumor suppressors#target#RNA polymerase I and interfere with rRNA synthesis
🏥 Tumorigenesis 📄 PMID: 18490923
#16827 middle Confidence
Subject: non-coding_RNA_Pol_II_transcripts (Noncoding RNA)
regulate
Object: nucleolus_assembly (Subcellular structure assembly)
Original: Non-coding RNA polymerase II transcripts#regulate#nucleolus assembly
🏥 not_specified 📄 PMID: 27416361
#16826 middle Confidence
Subject: cytochrome_C (protein)
cytoplasmic_accumulation
Object: caspase-9_activation (Protein activation events)
Original: Cytoplasmic accumulation of cytochrome C#was accompanied by#activation of caspase-9
🏥 Apoptosis 🧬 CYCS/CASP9 📄 PMID: 14642557
#16825 middle Confidence
Subject: MAGEB2_protein (protein)
promotes
Object: tumor_cell_proliferation (Tumor cell proliferation)
Original: MageB2 protein#promotes#tumor cell proliferation in a p53-independent fashion
🏥 Tumor proliferation 🧬 MAGEB2 📄 PMID: 26468294
#16824 middle Confidence
Subject: PNAs (Artificial nucleic acid)
contribute_to
Object: faithful_repair_of_rDNA_repeats (DNA repair events)
Original: PNAs#contribute to#sequestration and faithful repair of ribosomal DNA repeats
🏥 not_specified 📄 PMID: 31493766
#16823 middle Confidence
Subject: PNAs (Artificial nucleic acid)
contribute_to
Object: sequestration_of_rDNA_repeats (DNA structural events)
Original: PNAs#contribute to#sequestration and faithful repair of ribosomal DNA repeats
🏥 not_specified 📄 PMID: 31493766
#16822 middle Confidence
Subject: PML-nucleolar_interaction (Subcellular structure interactions)
is_associated_with
Object: reactivation_of_RNAP_I_transcription (Transcriptional activation events)
Original: PML-nucleolar interaction#is associated with#inactivation and reactivation of RNAP I transcription
🏥 not_specified 🧬 PML 📄 PMID: 31493766
#16821 middle Confidence
Subject: PML-nucleolar_interaction (Subcellular structure interactions)
is_associated_with
Object: inactivation_of_RNAP_I_transcription (Transcriptional repression events)
Original: PML-nucleolar interaction#is associated with#inactivation and reactivation of RNAP I transcription
🏥 not_specified 🧬 PML 📄 PMID: 31493766
#16820 middle Confidence
Subject: PTEN (Protein coding genes)
Dephosphorylates
Object: nucleolin (protein)
Original: PTEN�?localizes in#the nucleolus and dephosphorylates nucleolin
🏥 Signal regulation mechanism 🧬 PTEN/NCL 📄 PMID: 28332494
#16819 middle Confidence
Subject: NPM1 (Protein coding genes)
loss
Object: Stabilization_of_c-Myc (Protein stability)
Original: NPM1 loss#stabilizes#c-Myc
🏥 Tumorigenesis 🧬 NPM1/MYC 📄 PMID: 18625840
#16818 middle Confidence
Subject: nucleoli (Organelles)
become
Object: homogeneous_dense_structures (Cellular substructure)
Original: High dosages of cisplatin#transform#nucleoli into homogeneous dense structures
🏥 not_specified 📄 PMID: 1737358
#16817 middle Confidence
Subject: cisplatin (Chemotherapy drugs)
at_high_dosage_transforms
Object: nucleoli (Organelles)
Original: High dosages of cisplatin#transform#nucleoli into homogeneous dense structures
🏥 not_specified 📄 PMID: 1737358
#16816 middle Confidence
Subject: Surf-6_protein (Ribosome-associated proteins)
is_localized_in
Object: nucleolar_granular_component (Subcellular structure)
Original: Surf-6 protein#is localized in#nucleolar granular component
🏥 not_specified 📄 PMID: 8639267
#16815 middle Confidence
Subject: aminonucleoside (Small molecule drugs)
inhibits
Object: ribosomal_synthesis (Ribosome synthesis)
Original: Aminonucleoside#inhibits#ribosomal synthesis partially by reducing transcription rate
🏥 not_specified 📄 PMID: 457784
#16814 middle Confidence
Subject: aminonucleoside_pretreatment (Small molecule drug processing)
reduces_synthesis_of
Object: preribosomal_45S_RNA (pre-rRNA)
Original: Aminonucleoside pretreatment#reduces synthesis of#preribosomal 45S RNA
🏥 not_specified 📄 PMID: 457784
#16813 middle Confidence
Subject: aminonucleoside (Small molecule drugs)
does_not_impair
Object: nucleolar_chromatin_template_function (Nucleolar chromatin template function)
Original: Aminonucleoside#does not impair#template function of nucleolar chromatin
🏥 not_specified 📄 PMID: 457784