List of serched triples
A total of 22252 records found
#21632
high Confidence
Subject:
DICER1
(Protein coding genes)
→
mutated_in
→
Object:
chromatin_remodeling_pathway
(signaling pathway)
Original: Mutations in ATM/ BRCA1/ BRCA2/ ARID1A/ DICER1/ SMAD4/ NOTCH1/ and MYC amplification#were identified in#DNA damage repair and chromatin remodeling pathways in CCAs
#21631
high Confidence
Subject:
ARID1A
(Protein coding genes)
→
mutated_in
→
Object:
chromatin_remodeling_pathway
(signaling pathway)
Original: Mutations in ATM/ BRCA1/ BRCA2/ ARID1A/ DICER1/ SMAD4/ NOTCH1/ and MYC amplification#were identified in#DNA damage repair and chromatin remodeling pathways in CCAs
#21630
high Confidence
Subject:
BRCA2
(Protein coding genes)
→
mutated_in
→
Object:
DNA_damage_repair_pathway
(signaling pathway)
Original: Mutations in ATM/ BRCA1/ BRCA2/ ARID1A/ DICER1/ SMAD4/ NOTCH1/ and MYC amplification#were identified in#DNA damage repair and chromatin remodeling pathways in CCAs
#21629
high Confidence
Subject:
BRCA1
(Protein coding genes)
→
mutated_in
→
Object:
DNA_damage_repair_pathway
(signaling pathway)
Original: Mutations in ATM/ BRCA1/ BRCA2/ ARID1A/ DICER1/ SMAD4/ NOTCH1/ and MYC amplification#were identified in#DNA damage repair and chromatin remodeling pathways in CCAs
#21628
high Confidence
Subject:
ATM
(Protein coding genes)
→
mutated_in
→
Object:
DNA_damage_repair_pathway
(signaling pathway)
Original: Mutations in ATM/ BRCA1/ BRCA2/ ARID1A/ DICER1/ SMAD4/ NOTCH1/ and MYC amplification#were identified in#DNA damage repair and chromatin remodeling pathways in CCAs
#21627
high Confidence
Subject:
TFE3
(Transcription Factors)
→
rearrangement_associates_with
→
Object:
melanotic_Xp11_neoplasms
(Tumor type)
Original: TFE3 rearrangement-associated tumors#include#PEComas/ melanotic Xp11 translocation renal cancers/ melanotic Xp11 neoplasms
#21626
high Confidence
Subject:
TFE3
(Transcription Factors)
→
rearrangement_associates_with
→
Object:
melanotic_Xp11_translocation_renal_cancers
(Tumor type)
Original: TFE3 rearrangement-associated tumors#include#PEComas/ melanotic Xp11 translocation renal cancers/ melanotic Xp11 neoplasms
#21625
high Confidence
Subject:
TFE3
(Transcription Factors)
→
rearrangement_associates_with
→
Object:
PEComas
(Tumor type)
Original: TFE3 rearrangement-associated tumors#include#PEComas/ melanotic Xp11 translocation renal cancers/ melanotic Xp11 neoplasms
#21624
high Confidence
Subject:
fusion_analysis
(Molecular detection methods)
→
is_important_for
→
Object:
ALK-based_targeted_therapy
(Targeted therapy)
Original: Fusion analysis#is important for#RET-and ALK-based targeted therapies
#21623
high Confidence
Subject:
fusion_analysis
(Molecular detection methods)
→
is_important_for
→
Object:
RET-based_targeted_therapy
(Targeted therapy)
Original: Fusion analysis#is important for#RET-and ALK-based targeted therapies
#21622
high Confidence
Subject:
targeted_next_generation_sequencing_panel
(Molecular detection technology)
→
analyzes
→
Object:
cancer-related_genes
(Gene)
Original: 1425 cancer-related genes#were analyzed using#targeted next generation sequencing panel
#21621
high Confidence
Subject:
SWI/SNF_chromatin_remodeling_complex
(Protein complex)
→
acts_as
→
Object:
tumor_suppressor
(Functional phenotype)
Original: SWI/SNF chromatin remodeling complex#has#tumor suppressor roles in human cancers
#21620
high Confidence
Subject:
Fibrillarin
(Methyltransferase)
→
involved_in
→
Object:
ribosome_assembly
(Molecular complex assembly)
Original: Fibrillarin#is involved in#pre-rRNA processing/ methylation/ and ribosome assembly
#21619
high Confidence
Subject:
Fibrillarin
(Methyltransferase)
→
involved_in
→
Object:
rRNA_methylation
(Molecular modification)
Original: Fibrillarin#is involved in#pre-rRNA processing/ methylation/ and ribosome assembly
#21618
high Confidence
Subject:
Fibrillarin
(Methyltransferase)
→
involved_in
→
Object:
pre-rRNA_processing
(Molecular Process)
Original: Fibrillarin#is involved in#pre-rRNA processing/ methylation/ and ribosome assembly
#21617
high Confidence
Subject:
cellular_senescence
(Cellular Processes)
→
reduces
→
Object:
nucleolar_rRNA_synthesis
(Molecular Process)
Original: Cellular senescence#reduces#nucleolar rRNA synthesis and maturation
#21616
high Confidence
Subject:
silver_staining
(Molecular analysis technology)
→
was_applied_to
→
Object:
paraffin_blocked_tissue
(Tissue samples)
Original: Silver staining#was applied to#paraffin-blocked tissues from rectal cancer patients
#21615
high Confidence
Subject:
GCN2
(Protein kinase)
→
is_activated_by
→
Object:
uncharged_tRNA_accumulation
(Molecular accumulation)
Original: GCN2#is activated by#uncharged tRNA accumulation during amino acid shortage
#21614
high Confidence
Subject:
TP53BP1
(DNA damage repair proteins)
→
is_involved_in
→
Object:
DNA_damage_response
(DNA Damage Response)
Original: 53BP1 protein#is involved in#DNA damage response (DDR)
#21613
high Confidence
Subject:
TP53BP1
(DNA damage repair proteins)
→
is_upregulated_in
→
Object:
irradiated_genome
(Damaged genome)
Original: Increased levels of H2AX and 53BP1 proteins#were confirmed in#irradiated genome