Search results of triples

A total of 5 records found

#21567 high Confidence
Subject: CX5461 (Small molecule inhibitors)
→ targets →
Object: RNAPOL1 (RNA polymerase)
Original: CX5461#disrupts#nucleolar integrity by targeting RNAPOL1
🏥 Treatment Mechanism 🧬 POLR1 📄 PMID: 35673898
Details
#20379 high Confidence
Subject: CX5461 (Small molecule inhibitors)
→ disrupts →
Object: nucleolar_integrity (Subcellular structure)
Original: CX5461#disrupts#nucleolar integrity by targeting RNAPOL1
🏥 Treatment Mechanism 🧬 POLR1 📄 PMID: 35673898
Details
#20002 high Confidence
Subject: c-Myc (Transcription Factors)
→ induces →
Object: changes_in_nucleolar_structural_integrity (Changes in cell structure)
Original: c-Myc#induces#changes in nucleolar structural integrity
🏥 not_specified 🧬 MYC 📄 PMID: 20305389
Details
#6487 middle Confidence
Subject: Acr (Chemical drugs)
→ disrupts →
Object: nucleolar_integrity (Cell structure)
Original: Acr#disrupts#nucleolar integrity
🏥 not_specified 📄 PMID: 27741518
Details
#6280 middle Confidence
Subject: hNopp140 (Nucleolus-associated protein)
→ affects →
Object: nucleolar_integrity (Nucleolar structural integrity)
Original: hNopp140 overexpression#affects#nucleolar integrity
🏥 not_specified 🧬 Nopp140 📄 PMID: 10567578
Details