Search results of triples

A total of 24 records found

#21614 high Confidence
Subject: TP53BP1 (DNA damage repair proteins)
is_involved_in
Object: DNA_damage_response (DNA Damage Response)
Original: 53BP1 protein#is involved in#DNA damage response (DDR)
🏥 not_specified 🧬 TP53BP1 📄 PMID: 25369346
#20411 high Confidence
Subject: PLK1 (Protein kinase)
is_involved_in
Object: cell_cycle_regulation (Cell cycle regulation)
Original: Polo-like kinases (Plk1-4)#are involved in#cell cycle regulation and DNA damage response
🏥 not_specified 🧬 PLK1/PLK2/PLK3/PLK4 📄 PMID: 20100802
#20405 high Confidence
Subject: FBL (Ribosome biogenesis protein)
regulates
Object: tumorigenesis (Tumor development process)
Original: FBL#regulates#tumorigenesis and DNA damage response
🏥 Tumorigenesis 🧬 FBL 📄 PMID: 37489617
#20356 high Confidence
Subject: Oxaliplatin (Chemotherapy drugs)
activates
Object: DNA_damage_response (Cellular Processes)
Original: oxaliplatin#activated#DNA damage response
🏥 Treatment related 📄 PMID: 28478306
#19190 middle Confidence
Subject: p33ING1_CSIG_axis (Molecular complex)
functions_as
Object: pro-apoptotic_regulator (Molecular function)
Original: p33ING1-CSIG axis#functions as#a pro-apoptotic regulator in response to DNA damage
🏥 not_specified 🧬 ING1/CSIG 📄 PMID: 22419112
#17023 middle Confidence
Subject: E2F1 (Transcription Factors)
regulates
Object: apoptosis (Cellular Processes)
Original: Transcription factor E2F1#plays roles in#cell cycle arrest/ DNA repair/ or apoptosis in response to DNA damage
🏥 not_specified 🧬 E2F1 📄 PMID: 24675884
#17022 middle Confidence
Subject: E2F1 (Transcription Factors)
regulates
Object: DNA_repair (Cellular Processes)
Original: Transcription factor E2F1#plays roles in#cell cycle arrest/ DNA repair/ or apoptosis in response to DNA damage
🏥 not_specified 🧬 E2F1 📄 PMID: 24675884
#17021 middle Confidence
Subject: E2F1 (Transcription Factors)
regulates
Object: cell_cycle_arrest (Cellular Processes)
Original: Transcription factor E2F1#plays roles in#cell cycle arrest/ DNA repair/ or apoptosis in response to DNA damage
🏥 not_specified 🧬 E2F1 📄 PMID: 24675884
#16855 middle Confidence
Subject: PLK1 (Protein kinase)
is_involved_in
Object: DNA_damage_response (DNA Damage Response)
Original: Polo-like kinases (Plk1-4)#are involved in#cell cycle regulation and DNA damage response
🏥 not_specified 🧬 PLK1/PLK2/PLK3/PLK4 📄 PMID: 20100802
#16854 middle Confidence
Subject: PLK4 (Protein kinase)
is_involved_in
Object: cell_cycle_regulation (Cell cycle regulation)
Original: Polo-like kinases (Plk1-4)#are involved in#cell cycle regulation and DNA damage response
🏥 not_specified 🧬 PLK1/PLK2/PLK3/PLK4 📄 PMID: 20100802
#16853 middle Confidence
Subject: PLK3 (Protein kinase)
is_involved_in
Object: cell_cycle_regulation (Cell cycle regulation)
Original: Polo-like kinases (Plk1-4)#are involved in#cell cycle regulation and DNA damage response
🏥 not_specified 🧬 PLK1/PLK2/PLK3/PLK4 📄 PMID: 20100802
#16852 middle Confidence
Subject: PLK2 (Protein kinase)
is_involved_in
Object: cell_cycle_regulation (Cell cycle regulation)
Original: Polo-like kinases (Plk1-4)#are involved in#cell cycle regulation and DNA damage response
🏥 not_specified 🧬 PLK1/PLK2/PLK3/PLK4 📄 PMID: 20100802
#16838 middle Confidence
Subject: FBL (Ribosome biogenesis protein)
regulates
Object: DNA_damage_response (DNA Damage Response)
Original: FBL#regulates#tumorigenesis and DNA damage response
🏥 not_specified 🧬 FBL 📄 PMID: 37489617
#12355 middle Confidence
Subject: NuMA (Cytoskeletal proteins)
is_involved_in
Object: p53-mediated_growth_arrest (Cell cycle arrest)
Original: NuMA#is involved in#DNA damage response/ apoptosis/ and p53-mediated growth arrest under nucleolar stress
🏥 not_specified 🧬 NUMA1 📄 PMID: 28981686
#12354 middle Confidence
Subject: NuMA (Cytoskeletal proteins)
is_involved_in
Object: apoptosis (Apoptosis)
Original: NuMA#is involved in#DNA damage response/ apoptosis/ and p53-mediated growth arrest under nucleolar stress
🏥 not_specified 🧬 NUMA1 📄 PMID: 28981686
#12353 middle Confidence
Subject: NuMA (Cytoskeletal proteins)
is_involved_in
Object: DNA_damage_response (Cellular stress response)
Original: NuMA#is involved in#DNA damage response/ apoptosis/ and p53-mediated growth arrest under nucleolar stress
🏥 not_specified 🧬 NUMA1 📄 PMID: 28981686
#12232 middle Confidence
Subject: PLK4 (Protein kinase)
is_involved_in
Object: DNA_damage_response (DNA Damage Response)
Original: Polo-like kinases (Plk1-4)#are involved in#cell cycle regulation and DNA damage response
🏥 not_specified 🧬 PLK1/PLK2/PLK3/PLK4 📄 PMID: 20100802
#12231 middle Confidence
Subject: PLK3 (Protein kinase)
is_involved_in
Object: DNA_damage_response (DNA Damage Response)
Original: Polo-like kinases (Plk1-4)#are involved in#cell cycle regulation and DNA damage response
🏥 not_specified 🧬 PLK1/PLK2/PLK3/PLK4 📄 PMID: 20100802
#12230 middle Confidence
Subject: PLK2 (Protein kinase)
is_involved_in
Object: DNA_damage_response (DNA Damage Response)
Original: Polo-like kinases (Plk1-4)#are involved in#cell cycle regulation and DNA damage response
🏥 not_specified 🧬 PLK1/PLK2/PLK3/PLK4 📄 PMID: 20100802
#12186 middle Confidence
Subject: nucleolus (Organelles)
acts_as
Object: stress_sensor (Functional Mechanism)
Original: Nucleolus#acts as#a stress sensor contributing to DNA damage response
🏥 DNA Damage Response 📄 PMID: 30165463
#12000 middle Confidence
Subject: DNA_damage_response (Cellular Processes)
triggers
Object: nucleolar_and_ribosomal_stress (Molecular stress response)
Original: DNA damage response#triggered#nucleolar and ribosomal stress
🏥 not_specified 📄 PMID: 28478306
#10736 middle Confidence
Subject: p53-independent_pathway (signaling pathway)
regulates
Object: antigen_translocation (Subcellular structure process)
Original: p53-independent pathway#regulates#nucleolar segregation and antigen translocation in response to DNA damage
🏥 not_specified 🧬 TP53 📄 PMID: 14720517
#10735 middle Confidence
Subject: p53-independent_pathway (signaling pathway)
regulates
Object: nucleolar_segregation (Subcellular structure process)
Original: p53-independent pathway#regulates#nucleolar segregation and antigen translocation in response to DNA damage
🏥 not_specified 🧬 TP53 📄 PMID: 14720517
#6596 middle Confidence
Subject: transformed_keratinocytes (Cell Type)
exhibit
Object: inflammation (Inflammatory response)
Original: Transformed keratinocytes#exhibited#increased DNA damage and inflammation
🏥 Inflammatory response 📄 PMID: 34434485