List of serched triples

A total of 22252 records found

#17232 middle Confidence
Subject: DEPDC1B (Protein coding genes)
→ downregulates →
Object: FN1 (Protein coding genes)
Original: Knockdown of DEPDC1B#downregulates#NID1/ FN1/ and EGFR
🏥 Signaling pathway regulation 🧬 DEPDC1B/NID1/FN1/EGFR 📄 PMID: 38940035
Details
#17231 middle Confidence
Subject: DEPDC1B (Protein coding genes)
→ downregulates →
Object: NID1 (Protein coding genes)
Original: Knockdown of DEPDC1B#downregulates#NID1/ FN1/ and EGFR
🏥 Signaling pathway regulation 🧬 DEPDC1B/NID1/FN1/EGFR 📄 PMID: 38940035
Details
#17230 middle Confidence
Subject: CircRNAs (Circular RNA)
→ regulate →
Object: metastasis (Transfer process)
Original: CircRNAs#regulate#tumorigenesis and metastasis
🏥 Transfer Mechanism 📄 PMID: 30844715
Details
#17229 middle Confidence
Subject: CircRNAs (Circular RNA)
→ regulate →
Object: tumorigenesis (Tumor development process)
Original: CircRNAs#regulate#tumorigenesis and metastasis
🏥 Carcinogenic mechanism 📄 PMID: 30844715
Details
#17228 middle Confidence
Subject: SPC25 (Protein coding genes)
→ regulates →
Object: immune_cell_infiltration (Immune cell infiltration)
Original: SPC25#regulates#immune cell infiltration levels in the tumor microenvironment
🏥 Immunomodulation 🧬 SPC25 📄 PMID: 38420826
Details
#17227 middle Confidence
Subject: SPC25 (Protein coding genes)
→ promotes →
Object: cell_proliferation (Cellular Processes)
Original: SPC25#encouraged#tumor cell proliferation and growth
🏥 Tumorigenesis 🧬 SPC25 📄 PMID: 38420826
Details
#17226 middle Confidence
Subject: CD146 (Cell adhesion molecules)
→ suppresses →
Object: cell_invasion (Cellular Processes)
Original: Knocking down CD146#suppresses#cell migration and invasion in NSCLC
🏥 Metastasis suppression 📄 PMID: 38682195
Details
#17225 middle Confidence
Subject: CD146 (Cell adhesion molecules)
→ suppresses →
Object: cell_migration (Cellular Processes)
Original: Knocking down CD146#suppresses#cell migration and invasion in NSCLC
🏥 Metastasis suppression 📄 PMID: 38682195
Details
#17224 middle Confidence
Subject: CD146 (Cell adhesion molecules)
→ is_upregulated_in →
Object: NSCLC_tissues (Tumor tissue)
Original: CD146 expression levels#are assessed in#NSCLC cell lines and tissues
🏥 Tumor Diagnosis 📄 PMID: 38682195
Details
#17223 middle Confidence
Subject: CD146 (Cell adhesion molecules)
→ is_upregulated_in →
Object: NSCLC_cells (Tumor cells)
Original: CD146 expression levels#are assessed in#NSCLC cell lines and tissues
🏥 Tumor Diagnosis 📄 PMID: 38682195
Details
#17222 middle Confidence
Subject: Dipyridamole (Small molecule drugs)
→ increases →
Object: intracellular_Doxorubicin (Small molecule drugs)
Original: DPM#increases#cellular DOX by inhibiting drug efflux from cells
🏥 Drug influx regulation 📄 PMID: 1917161
Details
#17221 middle Confidence
Subject: Dipyridamole (Small molecule drugs)
→ inhibits →
Object: drug_efflux (Cellular Processes)
Original: DPM#increases#cellular DOX by inhibiting drug efflux from cells
🏥 Drug influx regulation 📄 PMID: 1917161
Details
#17220 middle Confidence
Subject: Doxorubicin (Chemotherapy drugs)
→ inhibits →
Object: cell_growth (Cell proliferation)
Original: DOX#induces#nucleophosmin translocation from the nucleolus to nucleoplasm and inhibits cell growth in a time- and dose-dependent manner
🏥 treat 🧬 NPM1 📄 PMID: 1917161
Details
#17219 middle Confidence
Subject: Doxorubicin (Chemotherapy drugs)
→ induces →
Object: nucleophosmin_translocation (Subcellular transport)
Original: DOX#induces#nucleophosmin translocation from the nucleolus to nucleoplasm and inhibits cell growth in a time- and dose-dependent manner
🏥 not_specified 🧬 NPM1 📄 PMID: 1917161
Details
#17218 middle Confidence
Subject: Dipyridamole (Chemotherapy drugs)
→ enhances →
Object: doxorubicin_sensitivity (Drug sensitivity)
Original: Dipyridamole (DPM)#enhanced#sensitivity to doxorubicin (DOX) in a human leukemia cell line
🏥 treat 📄 PMID: 1917161
Details
#17217 middle Confidence
Subject: TERC (Noncoding RNA)
→ is_found_in →
Object: nucleolus (Cellular substructure)
Original: hTR#is found in#the nucleolus
🏥 not_specified 🧬 TERC 📄 PMID: 11956201
Details
#17216 middle Confidence
Subject: TOP1 (DNA topoisomerase)
→ expression_correlates_with →
Object: in_vitro_chemosensitivity (Drug sensitivity)
Original: Expression of topoisomerase genes#is correlated with#in vitro chemosensitivity
🏥 Prediction of drug sensitivity 🧬 TOP1/ TOP2A/ TOP2B 📄 PMID: 8547322
Details
#17215 middle Confidence
Subject: NCL (Ribosomal proteins)
→ acts_as_receptor_for →
Object: Tipalpha (Bacterial toxin protein)
Original: Nucleolin#acts as#a receptor for Tipalpha in mouse gastric cancer cells
🏥 Infection-related mechanisms 🧬 NCL 📄 PMID: 20460757
Details
#17214 middle Confidence
Subject: p27BBP (Ribosomal proteins)
→ shows_increased_nucleolar_component_in →
Object: dysplastic_adenomas (Disease phenotype)
Original: p27BBP#displays#a large increase of its nucleolar component in dysplastic adenomas and carcinomas
🏥 Tumorigenesis 🧬 p27BBP 📄 PMID: 10676626
Details
#17213 middle Confidence
Subject: p27BBP (Ribosomal proteins)
→ is_decreased_in →
Object: apoptotic_villous_cells (Cellular Processes)
Original: p53 gene alterations#are associated with#malignant activity of tumor cells
🏥 Mechanism of apoptosis 🧬 TP53 📄 PMID: 9852302
Details