List of serched triples

A total of 22252 records found

#17052 middle Confidence
Subject: RPL22 (Ribosomal proteins)
→ triggers →
Object: heterochromatin_decompaction (Chromatin structural changes)
Original: RPL22 accumulation#triggers#heterochromatin decompaction and degradation of HP1α and KAP1
🏥 not_specified 🧬 RPL22/HP1α/KAP1 📄 PMID: 39258545
Details
#17051 middle Confidence
Subject: TIF-IA (Transcription Factors)
→ increases →
Object: oxidative_stress (Oxidative stress)
Original: Loss of TIF-IA#increases#oxidative stress
🏥 not_specified 🧬 TIF-IA 📄 PMID: 28360124
Details
#17050 middle Confidence
Subject: B23 (Ribosomal proteins)
→ depletion_induces →
Object: CENP-W_mislocalization (Abnormal protein localization)
Original: B23 depletion#induces#a decrease of CENP-W stability and mislocalization during prophase
🏥 not_specified 🧬 CENPW 📄 PMID: 22002061
Details
#17049 middle Confidence
Subject: B23 (Ribosomal proteins)
→ depletion_induces →
Object: CENP-W_stability (Protein stability)
Original: B23 depletion#induces#a decrease of CENP-W stability and mislocalization during prophase
🏥 not_specified 🧬 CENPW 📄 PMID: 22002061
Details
#17048 middle Confidence
Subject: CENP-W (Centromere protein)
→ interacts_with →
Object: CENP-T (Centromere protein)
Original: CENP-W#interacts with#CENP-T
🏥 not_specified 🧬 CENPW/CENPT 📄 PMID: 22002061
Details
#17047 middle Confidence
Subject: KRAS4B (Small GTPases)
→ localization_is_downregulated_by →
Object: Nucleolin (Ribosomal proteins)
Original: Nucleolin knockdown#eliminates#nucleolar localization of K-Ras4B
🏥 not_specified 🧬 NCL/KRAS 📄 PMID: 16889753
Details
#17046 middle Confidence
Subject: Nucleolin (Ribosomal proteins)
→ knockdown_eliminates →
Object: nucleolar_localization_of_KRAS4B (Protein localization process)
Original: Nucleolin knockdown#eliminates#nucleolar localization of K-Ras4B
🏥 not_specified 🧬 NCL/KRAS 📄 PMID: 16889753
Details
#17045 middle Confidence
Subject: KRAS4B (Small GTPases)
→ is_expressed_in →
Object: majority_of_human_cell_types (Cell Type)
Original: K-Ras4B#is expressed in#majority of human cell types
🏥 not_specified 🧬 KRAS 📄 PMID: 16889753
Details
#17044 middle Confidence
Subject: PtdIns(3/4/5)P3 (Phospholipid molecules)
→ regulates →
Object: nucleolar_processes (Nuclear function process)
Original: p110�?and PtdIns(3/4/5)P3#regulate#nucleolar processes via EBP1
🏥 not_specified 🧬 PIK3CA 📄 PMID: 27118868
Details
#17043 middle Confidence
Subject: p110α (PI3K catalytic subunit)
→ regulates →
Object: nucleolar_processes (Nuclear function process)
Original: p110�?and PtdIns(3/4/5)P3#regulate#nucleolar processes via EBP1
🏥 not_specified 🧬 PIK3CA 📄 PMID: 27118868
Details
#17042 middle Confidence
Subject: K372N_mutation (Point mutation)
→ alters →
Object: nucleolar_targeting_of_EBP1 (Protein localization process)
Original: K372N mutation#alters#nucleolar targeting of EBP1
🏥 not_specified 🧬 EBP1 📄 PMID: 27118868
Details
#17041 middle Confidence
Subject: EBP1 (Ribosome-associated proteins)
→ is_located_in →
Object: nucleolus (Cellular substructure)
Original: EBP1#is located in#cytoplasm and nucleolus
🏥 not_specified 🧬 EBP1 📄 PMID: 27118868
Details
#17040 middle Confidence
Subject: EBP1 (Ribosome-associated proteins)
→ is_located_in →
Object: Cytoplasm (Cellular substructure)
Original: EBP1#is located in#cytoplasm and nucleolus
🏥 not_specified 🧬 EBP1 📄 PMID: 27118868
Details
#17039 middle Confidence
Subject: polyphosphoinositides (Small molecules/metabolites)
→ participate_in →
Object: mRNA_processing (Molecular Biology Process)
Original: Polyphosphoinositides (PPIns)#participate in#chromatin remodeling/ transcription/ and mRNA processing
🏥 not_specified 📄 PMID: 27118868
Details
#17038 middle Confidence
Subject: polyphosphoinositides (Small molecules/metabolites)
→ participate_in →
Object: transcription (Molecular Biology Process)
Original: Polyphosphoinositides (PPIns)#participate in#chromatin remodeling/ transcription/ and mRNA processing
🏥 not_specified 📄 PMID: 27118868
Details
#17037 middle Confidence
Subject: polyphosphoinositides (Small molecules/metabolites)
→ participate_in →
Object: chromatin_remodeling (Molecular Biology Process)
Original: Polyphosphoinositides (PPIns)#participate in#chromatin remodeling/ transcription/ and mRNA processing
🏥 not_specified 📄 PMID: 27118868
Details
#17036 middle Confidence
Subject: DJ1 (Protein coding genes)
→ alters →
Object: rRNA_biogenesis (Molecular Biology Process)
Original: Mutant DJ-1 L166P#alters#rRNA biogenesis
🏥 not_specified 🧬 DJ1 📄 PMID: 22532838
Details
#17035 middle Confidence
Subject: large_gene_deletion (Genetic variation)
→ is_linked_to →
Object: loss_of_function_phenotype (Molecular functional phenotype)
Original: Large gene deletions#are linked to#a loss-of-function phenotype
🏥 not_specified 📄 PMID: 22532838
Details
#17034 middle Confidence
Subject: p14_ARF (Tumor suppressor proteins)
→ enhances →
Object: p53-mediated_apoptosis (Cellular Processes)
Original: p14 ARF#enhances#p53-mediated apoptosis after DNA damage and oncogene activation
🏥 Apoptosis regulation 🧬 CDKN2A/TP53 📄 PMID: 16267006
Details
#17033 middle Confidence
Subject: EAPB0503 (Small molecule drugs)
→ restores →
Object: wt-NPM1_nucleolar_localization (Protein localization phenotype)
Original: EAPB0503#restores#wt-NPM1 nucleolar localization in NPM1c AML cells
🏥 Treatment related 🧬 NPM1 📄 PMID: 28055106
Details