List of serched triples
A total of 22252 records found
#17032
middle Confidence
Subject:
EAPB0503
(Small molecule drugs)
→
induces
→
Object:
proteasome-mediated_degradation_of_NPM1c
(Protein degradation phenotype)
Original: EAPB0503#induces#proteasome-mediated degradation of NPM1c
#17031
middle Confidence
Subject:
NS1
(Viral Protein)
→
induces
→
Object:
nucleolar_stress
(Cellular stress process)
Original: NS1 protein of H3N2#induces#nucleolar stress based on epigenetic alteration of rRNA gene promoter
#17030
middle Confidence
Subject:
MDM2
(E3 ubiquitin ligase)
→
upregulates
→
Object:
p53
(Tumor suppressor proteins)
Original: NS1 expressed cells#showed#significant association of ribosomal proteins with MDM2 and p53 accumulation
#17029
middle Confidence
Subject:
ribosomal_proteins
(Ribosomal proteins)
→
associate_with
→
Object:
p53
(Tumor suppressor proteins)
Original: NS1 expressed cells#showed#significant association of ribosomal proteins with MDM2 and p53 accumulation
#17028
middle Confidence
Subject:
ribosomal_proteins
(Ribosomal proteins)
→
associate_with
→
Object:
MDM2
(E3 ubiquitin ligase)
Original: NS1 expressed cells#showed#significant association of ribosomal proteins with MDM2 and p53 accumulation
#17027
middle Confidence
Subject:
NS1
(Viral Protein)
→
induces
→
Object:
nucleolar_stress
(Cellular stress process)
Original: Non-structural protein 1 of H3N2 influenza A virus#induces#nucleolar stress via interaction with nucleolin
#17026
middle Confidence
Subject:
NS1
(Viral Protein)
→
interacts_with
→
Object:
NCL
(Ribosome-associated proteins)
Original: Non-structural protein 1 of H3N2 influenza A virus#induces#nucleolar stress via interaction with nucleolin
#17025
middle Confidence
Subject:
Olomoucine
(Small molecule drugs)
→
induces
→
Object:
nuclear_accumulation_of_wt_p53
(Protein localization phenotype)
Original: Roscovitine and olomoucine#induce#nuclear accumulation of wt p53 and nucleolar unravelling
#17024
middle Confidence
Subject:
Roscovitine
(Small molecule drugs)
→
induces
→
Object:
nuclear_accumulation_of_wt_p53
(Protein localization phenotype)
Original: Roscovitine and olomoucine#induce#nuclear accumulation of wt p53 and nucleolar unravelling
#17023
middle Confidence
Subject:
E2F1
(Transcription Factors)
→
regulates
→
Object:
apoptosis
(Cellular Processes)
Original: Transcription factor E2F1#plays roles in#cell cycle arrest/ DNA repair/ or apoptosis in response to DNA damage
#17022
middle Confidence
Subject:
E2F1
(Transcription Factors)
→
regulates
→
Object:
DNA_repair
(Cellular Processes)
Original: Transcription factor E2F1#plays roles in#cell cycle arrest/ DNA repair/ or apoptosis in response to DNA damage
#17021
middle Confidence
Subject:
E2F1
(Transcription Factors)
→
regulates
→
Object:
cell_cycle_arrest
(Cellular Processes)
Original: Transcription factor E2F1#plays roles in#cell cycle arrest/ DNA repair/ or apoptosis in response to DNA damage
#17020
middle Confidence
Subject:
POLR1A
(RNA polymerase I subunit)
→
downregulation_inactivates
→
Object:
MDM2-mediated_p53_degradation
(Protein degradation process)
Original: Downregulation of rRNA synthesis#inactivates#MDM2-mediated p53 degradation
#17019
middle Confidence
Subject:
POLR1A
(RNA polymerase I subunit)
→
downregulation_stabilises
→
Object:
TP53
(Transcription Factors)
Original: Downregulation of rRNA synthesis#stabilises#p53
#17018
middle Confidence
Subject:
PARP1
(poly ADP-ribose polymerase)
→
promotes
→
Object:
genomic_integrity
(Genome stability)
Original: PARP-1#promotes#genomic integrity through DNA repair and signaling pathways
#17017
middle Confidence
Subject:
TERF2
(Telomere binding protein)
→
binds_to
→
Object:
rDNA
(RNA)
Original: Nucleolar TRF2#binds#rDNA and promotes rRNA transcription
#17016
middle Confidence
Subject:
TERF2
(Telomere binding protein)
→
localizes_in
→
Object:
nucleolus
(Cellular substructure)
Original: TRF2#localizes in#the nucleolus in a cell-cycle-dependent manner
#17015
middle Confidence
Subject:
NPM1
(Nucleolar proteins)
→
blocks
→
Object:
increases_in_Arf(-/-)_osteoclast_activity
(Cellular Processes)
Original: Knockdown of NPM#blocks#increases in Arf(-/-) ribosome output and osteoclast activity
#17014
middle Confidence
Subject:
NPM1
(Nucleolar proteins)
→
blocks
→
Object:
increases_in_Arf(-/-)_ribosome_output
(Molecular Process)
Original: Knockdown of NPM#blocks#increases in Arf(-/-) ribosome output and osteoclast activity
#17013
middle Confidence
Subject:
Nucleostemin
(Nucleoside protein)
→
is_involved_in
→
Object:
regulation_of_cell_proliferation
(Cellular Processes)
Original: Nucleostemin (NS)#is involved in#regulation of cell proliferation