List of serched triples

A total of 22252 records found

#20072 high Confidence
Subject: NPM1 (Protein coding genes)
is_overexpressed_in
Object: tumor (Tumor phenotype)
Original: Nucleophosmin (NPM)#is found overexpressed in#many types of tumors
🏥 Tumor markers 🧬 NPM1 📄 PMID: 22665062
#20071 high Confidence
Subject: MYC (Protein coding genes)
activates
Object: RNA_polymerase_I_transcription (Transcription process)
Original: c-Myc#activates#RNA polymerase I-mediated transcription of ribosomal RNA genes
🏥 Ribosome biogenesis 🧬 MYC 📄 PMID: 22665062
#20070 high Confidence
Subject: TIF-IA (Transcription Factors)
is_inactivated_by
Object: homologous_recombination (Gene Editing Technology)
Original: TIF-IA gene#was inactivated by#homologous recombination in mice and MEFs
🏥 not_specified 🧬 TIF-IA 📄 PMID: 15989966
#20069 high Confidence
Subject: translation_machinery_misregulation (Protein synthesis mechanism)
is_associated_with
Object: cancer (Disease phenotype)
Original: Mis-regulation of nucleolar functions and translation machinery#has been associated with#many types of cancer
🏥 Carcinogenic mechanism 📄 PMID: 28846478
#20068 high Confidence
Subject: nucleolar_function_misregulation (Function of cellular substructures)
is_associated_with
Object: cancer (Disease phenotype)
Original: Mis-regulation of nucleolar functions and translation machinery#has been associated with#many types of cancer
🏥 Carcinogenic mechanism 📄 PMID: 28846478
#20067 high Confidence
Subject: Ribosome methylation profiles (Molecular Modification Omics)
is_altered_in
Object: cancer (Disease phenotype)
Original: snoRNA expression and ribosome methylation profiles#are altered in#cancer
🏥 Tumorigenesis 📄 PMID: 34775914
#20066 high Confidence
Subject: snoRNA expression (Noncoding RNA expression)
is_altered_in
Object: cancer (Disease phenotype)
Original: snoRNA expression and ribosome methylation profiles#are altered in#cancer
🏥 Tumorigenesis 📄 PMID: 34775914
#20065 high Confidence
Subject: DKC1 (Ribosome modifying enzymes)
catalysts
Object: pseudo-uridylation_of_rRNA (RNA modification)
Original: Dyskerin#carries out#pseudo-uridylation of rRNA and stabilization of telomerase RNA
🏥 not_specified 🧬 DKC1 📄 PMID: 16841302
#20064 high Confidence
Subject: ZGar (Virus)
leads_to
Object: nucleolar_structural_disruption (Changes in nucleolar structure)
Original: ZIKV infection#leads to#ribosomal stress and nucleolar structural disruption
🏥 not_specified 🧬 ZGar 📄 PMID: 29192272
#20063 high Confidence
Subject: ZGar (Virus)
leads_to
Object: ribosomal_stress (Stress response)
Original: ZIKV infection#leads to#ribosomal stress and nucleolar structural disruption
🏥 not_specified 🧬 ZGar 📄 PMID: 29192272
#20062 high Confidence
Subject: NOLC1 (Nucleolus-associated protein)
interacts_with
Object: fibrillarin (RNA methyltransferase)
Original: NOLC1#interacts with#fibrillarin in the nucleolus
🏥 not_specified 🧬 NOLC1/FBL 📄 PMID: 35365782
#20061 high Confidence
Subject: nucleolus_organizer_regions (Chromosome structural region)
are_used_in
Object: pathomorphologic_tumor_diagnosis (Tumor pathology diagnosis)
Original: Nucleolus organizer regions#are used in#pathomorphologic tumor diagnosis
🏥 Tumor Diagnosis 📄 PMID: 1413987
#20060 high Confidence
Subject: apoptosis_execution_phase (Cellular Processes)
is_characterized_by
Object: membrane_blebbing (Cell morphology changes)
Original: Apoptosis execution phase#is characterized by#membrane blebbing
🏥 not_specified 📄 PMID: 19630753
#20059 high Confidence
Subject: SGO2 (Protein coding genes)
promotes
Object: EMT (Cellular Processes)
Original: SGO2#promoted#cell proliferation/ cell migration/ invasion/ and EMT of A549 cells
🏥 Transfer related 🧬 SGO2 📄 PMID: 39344317
#20058 high Confidence
Subject: SGO2 (Protein coding genes)
promotes
Object: cell_invasion (Cellular Processes)
Original: SGO2#promoted#cell proliferation/ cell migration/ invasion/ and EMT of A549 cells
🏥 Transfer related 🧬 SGO2 📄 PMID: 39344317
#20057 high Confidence
Subject: SGO2 (Protein coding genes)
promotes
Object: cell_migration (Cellular Processes)
Original: SGO2#promoted#cell proliferation/ cell migration/ invasion/ and EMT of A549 cells
🏥 Transfer related 🧬 SGO2 📄 PMID: 39344317
#20056 high Confidence
Subject: SGO2 (Protein coding genes)
promotes
Object: cell_proliferation (Cellular Processes)
Original: SGO2#promoted#cell proliferation/ cell migration/ invasion/ and EMT of A549 cells
🏥 Cell proliferation regulation 🧬 SGO2 📄 PMID: 39344317
#20055 high Confidence
Subject: SGO2 (Protein coding genes)
facilitates
Object: cell_proliferation (Cellular Processes)
Original: SGO2#facilitated#cell proliferation and regulated cell cycle through upregulating E2F1
🏥 Cell proliferation regulation 🧬 SGO2/E2F1 📄 PMID: 39344317
#20054 high Confidence
Subject: SGO2 (Protein coding genes)
upregulates
Object: E2F1 (Transcription Factors)
Original: SGO2#facilitated#cell proliferation and regulated cell cycle through upregulating E2F1
🏥 Cell cycle regulation 🧬 SGO2/E2F1 📄 PMID: 39344317
#20053 high Confidence
Subject: SGO2 (Protein coding genes)
reduces
Object: cell_apoptosis (Cellular Processes)
Original: SGO2#contributed to#cell cycle progression and reduced cell apoptosis
🏥 Apoptosis regulation 🧬 SGO2 📄 PMID: 39344317