List of serched triples
A total of 22252 records found
#20092
high Confidence
Subject:
Nucleophosmin_1
(Nucleolar proteins)
→
regulates
→
Object:
ribosome_biogenesis
(Cellular Processes)
Original: Nucleophosmin 1 (NPM1)#regulates#centrosome duplication/ ribosome biogenesis and export/ histone assembly/ genomic stability/ and nucleolar stress response
#20091
high Confidence
Subject:
Nucleophosmin_1
(Nucleolar proteins)
→
regulates
→
Object:
centrosome_duplication
(Cellular Processes)
Original: Nucleophosmin 1 (NPM1)#regulates#centrosome duplication/ ribosome biogenesis and export/ histone assembly/ genomic stability/ and nucleolar stress response
#20090
high Confidence
Subject:
cAMP
(Small molecules)
→
activates
→
Object:
cAMP-dependent_protein_kinase
(Protein kinase)
Original: Cyclic AMP (cAMP)#activates#cyclic AMP-dependent protein kinase
#20089
high Confidence
Subject:
Cajal_bodies
(Subcellular structure)
→
contain
→
Object:
RNA_processing_components
(Molecular complex)
Original: Cajal bodies (CBs)#contain#components of RNA transcription and RNA processing pathways
#20088
high Confidence
Subject:
Cajal_bodies
(Subcellular structure)
→
contain
→
Object:
RNA_transcription_components
(Molecular complex)
Original: Cajal bodies (CBs)#contain#components of RNA transcription and RNA processing pathways
#20087
high Confidence
Subject:
targeted_therapeutics
(Targeted therapy drugs)
→
interrupt
→
Object:
bone_degradation
(Bone degradation process)
Original: targeted therapeutics#interrupt#cycle of tumor development and bone degradation
#20086
high Confidence
Subject:
targeted_therapeutics
(Targeted therapy drugs)
→
interrupt
→
Object:
tumor_development
(Tumor development process)
Original: targeted therapeutics#interrupt#cycle of tumor development and bone degradation
#20085
high Confidence
Subject:
NPM1
(Protein coding genes)
→
is_associated_with
→
Object:
cytoplasmic_localization_in_AML
(Abnormal molecular localization)
Original: One-third of acute myeloid leukemias (AMLs)#are associated with#aberrant localization of NPM1 to the cytoplasm (NPM1c+)
#20084
high Confidence
Subject:
p14ARF
(Tumor suppressor proteins)
→
increases
→
Object:
p21_expression
(Protein expression)
Original: p14ARF#increases#transcription and expression of p21
#20083
high Confidence
Subject:
p14ARF
(Tumor suppressor proteins)
→
inhibits
→
Object:
HDM2
(Ubiquitin ligase)
Original: p14ARF#activates#p53 by binding and inhibiting HDM2
#20082
high Confidence
Subject:
p14ARF
(Tumor suppressor proteins)
→
binds_to
→
Object:
HDM2
(Ubiquitin ligase)
Original: p14ARF#activates#p53 by binding and inhibiting HDM2
#20081
high Confidence
Subject:
p14ARF
(Tumor suppressor proteins)
→
activates
→
Object:
p53
(Transcription Factors)
Original: p14ARF#activates#p53 by binding and inhibiting HDM2
#20080
high Confidence
Subject:
p53_expression
(Protein expression)
→
is_useful_as
→
Object:
prognostic_indicator
(Clinical outcome measures)
Original: DNA ploidy and p53 expression#are useful as#prognostic indicators in HCC
#20079
high Confidence
Subject:
DNA_ploidy
(Genomic features)
→
is_useful_as
→
Object:
prognostic_indicator
(Clinical outcome measures)
Original: DNA ploidy and p53 expression#are useful as#prognostic indicators in HCC
#20078
high Confidence
Subject:
Dyskeratosis_congenita
(Genetic disorders)
→
is_associated_with
→
Object:
increased_cancer_susceptibility
(Disease phenotype)
Original: Dyskeratosis congenita#is associated with#increased susceptibility to cancer
#20077
high Confidence
Subject:
Hepatitis_delta_virus_protein
(Viral Protein)
→
localizes_to
→
Object:
nucleolus
(Subcellular structure)
Original: Hepatitis delta virus proteins#localize#to the nucleolus in the absence of viral RNA replication
#20076
high Confidence
Subject:
guanine_nucleotide_depletion
(Metabolic status)
→
causes
→
Object:
nucleolar_protein_translocation
(Subcellular structural changes)
Original: Depletion of guanine nucleotides by MPA and AVN-944#causes#translocation of nucleolar proteins to the nucleoplasm
#20075
high Confidence
Subject:
guanine_nucleotide
(Small molecule metabolites)
→
depletion
→
Object:
45S_precursor_rRNA_synthesis
(rRNA transcription synthesis)
Original: Depletion of guanine nucleotides by MPA and AVN-944#causes#a reduction in levels of 45S precursor rRNA synthesis
#20074
high Confidence
Subject:
PPP2CB
(Protein coding genes)
→
enables
→
Object:
CDC14
(Protein coding genes)
Original: Downregulation of PP2A(Cdc55)#enables#release of Cdc14p from the nucleolus
#20073
high Confidence
Subject:
E
(Molecular complex)
→
suppresses
→
Object:
rRNA_transcription
(rRNA transcription process)
Original: eNoSC#suppresses#rRNA transcription in response to glucose starvation