List of serched triples

A total of 22252 records found

#21432 high Confidence
Subject: Adenomatoid_tumor (Tumor type)
is
Object: benign_neoplasm (Benign or malignant tumor)
Original: adenomatoid tumor#is#benign neoplasm
🏥 Diagnostic significance 📄 PMID: 14707867
#21431 high Confidence
Subject: fibroepithelial_lesions_of_breast (Fibroepithelial lesions of the breast)
were_classified_into
Object: malignant_phyllodes_tumour (Malignant phyllodes tumor)
Original: Fibroepithelial lesions of the breast#were classified into#fibroadenoma (FA)/ benign phyllodes tumours (PTLGM)/ borderline (PTBM)/ and malignant (PTHGM)
🏥 Diagnostic typing 📄 PMID: 15039920
#21430 high Confidence
Subject: fibroepithelial_lesions_of_breast (Fibroepithelial lesions of the breast)
were_classified_into
Object: borderline_phyllodes_tumour (Borderline phyllodes tumor)
Original: Fibroepithelial lesions of the breast#were classified into#fibroadenoma (FA)/ benign phyllodes tumours (PTLGM)/ borderline (PTBM)/ and malignant (PTHGM)
🏥 Diagnostic typing 📄 PMID: 15039920
#21429 high Confidence
Subject: fibroepithelial_lesions_of_breast (Fibroepithelial lesions of the breast)
were_classified_into
Object: benign_phyllodes_tumour (Benign phyllodes tumor)
Original: Fibroepithelial lesions of the breast#were classified into#fibroadenoma (FA)/ benign phyllodes tumours (PTLGM)/ borderline (PTBM)/ and malignant (PTHGM)
🏥 Diagnostic typing 📄 PMID: 15039920
#21428 high Confidence
Subject: fibroepithelial_lesions_of_breast (Fibroepithelial lesions of the breast)
were_classified_into
Object: fibroadenoma (Breast fibroadenoma)
Original: Fibroepithelial lesions of the breast#were classified into#fibroadenoma (FA)/ benign phyllodes tumours (PTLGM)/ borderline (PTBM)/ and malignant (PTHGM)
🏥 Diagnostic typing 📄 PMID: 15039920
#21427 high Confidence
Subject: Bortezomib (Proteasome inhibitors)
interferes_with
Object: protein_biosynthesis_at_nucleolar_ribosome_biogenesis_stage (Molecular Process)
Original: bortezomib#interferes with#protein biosynthesis at nucleolar ribosome biogenesis stage
🏥 Treatment Mechanism 📄 PMID: 27567537
#21426 high Confidence
Subject: NRG1 (Ligand protein)
activates
Object: ERBB_receptor_tyrosine_kinases (Receptor tyrosine kinases)
Original: Neuregulin 1 (NRG1)#activates#ErbB receptor tyrosine kinases
🏥 Signaling pathway regulation 🧬 NRG1/ERBB 📄 PMID: 34747541
#21425 high Confidence
Subject: EGFR (Receptor tyrosine kinases)
is_overexpressed_in
Object: FLC_tumors (Tumor tissue)
Original: EFGR overexpression#is evident in#FLC tumors
🏥 Diagnosis/treatment related 🧬 EGFR 📄 PMID: 37429175
#21424 high Confidence
Subject: mTOR_pathway (signaling pathway)
plays_critical_role_in
Object: FLC (Tumor type)
Original: mTOR pathway activation#plays#a critical role in 47% of FLC tumors
🏥 Therapeutic significance 🧬 MTOR 📄 PMID: 37429175
#21423 high Confidence
Subject: ribosomal_protein_genes_haploinsufficiency (Gene dosage abnormalities)
is_implicated_in
Object: 5q-syndrome (Genetic disorders)
Original: Haploinsufficiency of ribosomal protein genes#is implicated in#Diamond-Blackfan anemia and 5q-syndrome
🏥 Diagnostic significance 📄 PMID: 21068437
#21422 high Confidence
Subject: ribosomal_protein_genes_haploinsufficiency (Gene dosage abnormalities)
is_implicated_in
Object: Diamond-Blackfan_anemia (Genetic disorders)
Original: Haploinsufficiency of ribosomal protein genes#is implicated in#Diamond-Blackfan anemia and 5q-syndrome
🏥 Diagnostic significance 📄 PMID: 21068437
#21421 high Confidence
Subject: GRK5 (G protein-coupled receptor kinase)
is_localized_within
Object: nucleus (Cellular substructure)
Original: GRK5#is localized within#the nucleus and moderates DNA transcription
🏥 not_specified 🧬 GRK5 📄 PMID: 33507833
#21420 high Confidence
Subject: RS-OXA_conjugate (Small molecule drug conjugates)
localizes_to
Object: cell_nucleoli (Cellular substructure)
Original: RS-OXA conjugate#localizes to#cell nucleoli of HCC/ NSCLC/ breast/ colon and cervical cancer cells
🏥 not_specified 📄 PMID: 36049426
#21419 high Confidence
Subject: Peptide_RS (Peptides)
enables
Object: delineation_from_noncancerous_tissues (Tissue typing)
Original: Peptide RS#enables#improved HCC micrometastasis discrimination and delineation from noncancerous tissues
🏥 Diagnostic significance 📄 PMID: 36049426
#21418 high Confidence
Subject: Peptide_RS (Peptides)
enables
Object: HCC_micrometastasis_discrimination (Disease phenotype)
Original: Peptide RS#enables#improved HCC micrometastasis discrimination and delineation from noncancerous tissues
🏥 Diagnostic significance 📄 PMID: 36049426
#21417 high Confidence
Subject: Androgen (hormone)
activates
Object: androgen_receptor (Receptor protein)
Original: Androgen and androgen receptor (AR) pathways#have been associated with#prostate growth
🏥 not_specified 🧬 AR 📄 PMID: 27814623
#21416 high Confidence
Subject: p19(ARF) (Tumor suppressor proteins)
activates
Object: p53 (Transcription Factors)
Original: p19(ARF)#activates#p53 without affecting Mdm2 localization
🏥 not_specified 🧬 CDKN2A/TP53/MDM2 📄 PMID: 11309506
#21415 high Confidence
Subject: Hippo_pathway (signaling pathway)
restricts
Object: YAP_nuclear_entry (Transcription factor localization)
Original: activation of Hippo pathway#restricts#YAP nuclear entry via phosphorylation by Lats kinases
🏥 not_specified 🧬 YAP/LATS1/LATS2 📄 PMID: 25658431
#21414 high Confidence
Subject: WDR75 (Ribosomal histones)
is
Object: nucleolar_protein (Nucleolar proteins)
Original: endogenous human WDR75#is#a nucleolar protein
🏥 not_specified 🧬 WDR75 📄 PMID: 34611297
#21413 high Confidence
Subject: ribosomal_proteins_L11 (Ribosomal proteins)
binds_to
Object: MDM2 (Ubiquitin ligase)
Original: elevated levels of p53 after TIF-IA depletion#are due to#increased binding of ribosomal proteins (e.g./ L11) to MDM2 and decreased interaction of MDM2 with p53 and p19(ARF)
🏥 not_specified 🧬 TP53/RPL11/MDM2/CDKN2A 📄 PMID: 15989966