List of serched triples

A total of 22252 records found

#20472 high Confidence
Subject: nucleolin (Ribosomal proteins)
is_highly_expressed_in
Object: rapidly_dividing_cells (Cell Type)
Original: Nucleolin#is highly expressed in#rapidly dividing cells and cancer cell lines
🏥 not_specified 📄 PMID: 18637790
#20471 high Confidence
Subject: guanine_nucleotide (Small molecule metabolites)
depletion_by
Object: AVN-944 (Chemotherapy drugs)
Original: Depletion of guanine nucleotides by MPA and AVN-944#causes#translocation of nucleolar proteins to the nucleoplasm
🏥 Treatment related 📄 PMID: 17462731
#20470 high Confidence
Subject: guanine_nucleotide (Small molecule metabolites)
depletion_by
Object: MPA (Chemotherapy drugs)
Original: Depletion of guanine nucleotides by MPA and AVN-944#causes#translocation of nucleolar proteins to the nucleoplasm
🏥 Treatment related 📄 PMID: 17462731
#20469 high Confidence
Subject: guanine_nucleotide (Small molecule metabolites)
depletion_by
Object: AVN-944 (Chemotherapy drugs)
Original: Depletion of guanine nucleotides by MPA and AVN-944#causes#a reduction in levels of 45S precursor rRNA synthesis
🏥 Treatment related 📄 PMID: 17462731
#20468 high Confidence
Subject: guanine_nucleotide (Small molecule metabolites)
depletion_by
Object: MPA (Chemotherapy drugs)
Original: Depletion of guanine nucleotides by MPA and AVN-944#causes#a reduction in levels of 45S precursor rRNA synthesis
🏥 Treatment related 📄 PMID: 17462731
#20467 high Confidence
Subject: BLM (DNA helicase)
mutation_causes
Object: cancer-prone_syndromes (Disease phenotype)
Original: Mutations in WRN and BLM#cause#cancer-prone syndromes
🏥 Tumor susceptibility 🧬 WRN/BLM 📄 PMID: 17996922
#20466 high Confidence
Subject: WRN (DNA helicase)
mutation_causes
Object: cancer-prone_syndromes (Disease phenotype)
Original: Mutations in WRN and BLM#cause#cancer-prone syndromes
🏥 Tumor susceptibility 🧬 WRN/BLM 📄 PMID: 17996922
#20465 high Confidence
Subject: ZDS1 (Protein coding genes)
promotes
Object: PPP2CB (Protein coding genes)
Original: Separase together with Zds1p#promotes#downregulation of PP2A(Cdc55) in early anaphase
🏥 not_specified 🧬 ESPL1/ZDS1/PPP2CB 📄 PMID: 22427694
#20464 high Confidence
Subject: ESPL1 (Protein coding genes)
promotes
Object: PPP2CB (Protein coding genes)
Original: Separase together with Zds1p#promotes#downregulation of PP2A(Cdc55) in early anaphase
🏥 not_specified 🧬 ESPL1/ZDS1/PPP2CB 📄 PMID: 22427694
#20463 high Confidence
Subject: ZDS1 (Protein coding genes)
regulates
Object: CDC14 (Protein coding genes)
Original: Zds1#regulates#PP2A(Cdc55) activity and Cdc14 activation during mitotic exit
🏥 not_specified 🧬 ZDS1/PPP2CB/CDC14 📄 PMID: 22427694
#20462 high Confidence
Subject: ZDS1 (Protein coding genes)
regulates
Object: PPP2CB (Protein coding genes)
Original: Zds1#regulates#PP2A(Cdc55) activity and Cdc14 activation during mitotic exit
🏥 not_specified 🧬 ZDS1/PPP2CB/CDC14 📄 PMID: 22427694
#20461 high Confidence
Subject: human_genome (Genome)
contains
Object: APOBEC_cytidine_deaminases (Deaminase family)
Original: The human genome#contains#11 APOBEC cytidine deaminases classified into four families
🏥 not_specified 🧬 APOBEC 📄 PMID: 34528388
#20460 high Confidence
Subject: ALLN (Proteasome inhibitors)
inhibits
Object: Survivin-deltaEx3_degradation (Protein degradation process)
Original: Proteasome inhibitors MG132 or ALLN#inhibit#degradation of Survivin-deltaEx3
🏥 Therapeutic significance 🧬 BIRC5 📄 PMID: 15735764
#20459 high Confidence
Subject: MG132 (Proteasome inhibitors)
inhibits
Object: Survivin-deltaEx3_degradation (Protein degradation process)
Original: Proteasome inhibitors MG132 or ALLN#inhibit#degradation of Survivin-deltaEx3
🏥 Therapeutic significance 🧬 BIRC5 📄 PMID: 15735764
#20458 high Confidence
Subject: ATR (Protein kinase)
phosphorylates
Object: PML (Tumor suppressor proteins)
Original: ATR#phosphorylates#PML
🏥 not_specified 🧬 ATR/PML 📄 PMID: 15195100
#20457 high Confidence
Subject: PML (Tumor suppressor proteins)
enhances
Object: p53_stability (Protein stability)
Original: PML#enhances#p53 stability
🏥 not_specified 🧬 PML/TP53 📄 PMID: 15195100
#20456 high Confidence
Subject: PML (Tumor suppressor proteins)
potentiates
Object: p53_function (Protein function)
Original: PML tumour-suppressor protein#potentiates#p53 function
🏥 not_specified 🧬 PML/TP53 📄 PMID: 15195100
#20455 high Confidence
Subject: NPM1 (Protein coding genes)
is_critical_in
Object: ribosome_biogenesis (Ribosome biogenesis)
Original: Nucleophosmin (NPM)#is critical in#ribosome biogenesis
🏥 Ribosome production mechanism 🧬 NPM1 📄 PMID: 22665062
#20454 high Confidence
Subject: TP53 (Protein coding genes)
is_localized_to
Object: nucleus (Cellular substructure)
Original: p53#is localized to#the nucleus of human fibroblasts treated with UV light/ DRB/ or MG132
🏥 not_specified 🧬 TP53 📄 PMID: 11329373
#20453 high Confidence
Subject: TP53 (Transcription Factors)
accumulates_in
Object: nucleus (Cell structure)
Original: p53#accumulates in#the nucleus of cells exposed to various cellular stresses
🏥 not_specified 🧬 TP53 📄 PMID: 11329373