Search results of triples
A total of 151 records found
#22086
high Confidence
Subject:
small_cell_carcinoma
(Small cell carcinoma)
→
was_characterized_by
→
Object:
cohesive_clusters
(Adhesive clumps)
Original: Small cell carcinoma#was characterized by#cohesive clusters of small round cells with round to oval nuclei and scant cytoplasm
#21858
high Confidence
Subject:
Literature
(literature)
→
has_been
→
Object:
relatively_small_for_Tubulocystic_renal_cell_carcinoma
(Study sample size)
Original: Literature#has been#relatively small for tubulocystic renal cell carcinoma
#21794
high Confidence
Subject:
SCNEC
(Tumor)
→
has_high_propensity_for
→
Object:
distant_metastasis
(Metastatic phenotype)
Original: Small cell neuroendocrine carcinoma (SCNEC)#has#a high propensity for distant metastases
#21793
high Confidence
Subject:
SCNEC
(Tumor)
→
is_associated_with
→
Object:
poor_prognosis
(Prognosis)
Original: Small cell neuroendocrine carcinoma (SCNEC)#is#a rare/ highly aggressive tumor with poor prognosis
#21792
high Confidence
Subject:
SCNEC
(Tumor)
→
is
→
Object:
rare_highly_aggressive_tumor
(Tumor phenotype)
Original: Small cell neuroendocrine carcinoma (SCNEC)#is#a rare/ highly aggressive tumor with poor prognosis
#21377
high Confidence
Subject:
Neuroendocrine tumors
(Tumor type)
→
showed
→
Object:
Ki-67_index_80%
(Proliferation markers)
Original: Neuroendocrine tumors#showed#cells arranged in cords or nests with Ki-67 index of 5% (G2 neuroendocrine tumor) and 80% (small-cell neuroendocrine carcinoma)
#21336
high Confidence
Subject:
atypical_adenomatous_hyperplasia
(Benign lesions)
→
is_distinguished_from
→
Object:
well-differentiated_prostatic_adenocarcinoma
(Tumor type)
Original: Diagnosis of atypical adenomatous hyperplasia (AAH)#is distinguished from#well-differentiated prostatic adenocarcinoma with small acinar pattern (PACsmac)
#21283
high Confidence
Subject:
cytological_criteria_for_SCLC
(Diagnostic criteria)
→
include
→
Object:
necrotic_debris
(Cytological characteristics)
Original: cytological criteria for diagnosis of SCLC#include#high cellularity/ small cell size/ scant cytoplasm/ coarsely granulated chromatin/ inconspicuous nucleoli/ Azzopardi crush effect/ and necrotic debris
#21282
high Confidence
Subject:
cytological_criteria_for_SCLC
(Diagnostic criteria)
→
include
→
Object:
Azzopardi_crush_effect
(Cytological characteristics)
Original: cytological criteria for diagnosis of SCLC#include#high cellularity/ small cell size/ scant cytoplasm/ coarsely granulated chromatin/ inconspicuous nucleoli/ Azzopardi crush effect/ and necrotic debris
#21281
high Confidence
Subject:
cytological_criteria_for_SCLC
(Diagnostic criteria)
→
include
→
Object:
inconspicuous_nucleoli
(Cytological characteristics)
Original: cytological criteria for diagnosis of SCLC#include#high cellularity/ small cell size/ scant cytoplasm/ coarsely granulated chromatin/ inconspicuous nucleoli/ Azzopardi crush effect/ and necrotic debris
#21280
high Confidence
Subject:
cytological_criteria_for_SCLC
(Diagnostic criteria)
→
include
→
Object:
coarsely_granulated_chromatin
(Cytological characteristics)
Original: cytological criteria for diagnosis of SCLC#include#high cellularity/ small cell size/ scant cytoplasm/ coarsely granulated chromatin/ inconspicuous nucleoli/ Azzopardi crush effect/ and necrotic debris
#21279
high Confidence
Subject:
cytological_criteria_for_SCLC
(Diagnostic criteria)
→
include
→
Object:
scant_cytoplasm
(Cytological characteristics)
Original: cytological criteria for diagnosis of SCLC#include#high cellularity/ small cell size/ scant cytoplasm/ coarsely granulated chromatin/ inconspicuous nucleoli/ Azzopardi crush effect/ and necrotic debris
#21278
high Confidence
Subject:
cytological_criteria_for_SCLC
(Diagnostic criteria)
→
include
→
Object:
small_cell_size
(Cytological characteristics)
Original: cytological criteria for diagnosis of SCLC#include#high cellularity/ small cell size/ scant cytoplasm/ coarsely granulated chromatin/ inconspicuous nucleoli/ Azzopardi crush effect/ and necrotic debris
#21277
high Confidence
Subject:
cytological_criteria_for_SCLC
(Diagnostic criteria)
→
include
→
Object:
high_cellularity
(Cytological characteristics)
Original: cytological criteria for diagnosis of SCLC#include#high cellularity/ small cell size/ scant cytoplasm/ coarsely granulated chromatin/ inconspicuous nucleoli/ Azzopardi crush effect/ and necrotic debris
#21276
high Confidence
Subject:
small-cell_lung_carcinoma
(Tumor type)
→
belongs_to
→
Object:
neuroendocrine_group_of_lung_tumors
(Tumor classification)
Original: Small-cell lung carcinoma (SCLC)#belongs to#neuroendocrine group of lung tumors
#21200
high Confidence
Subject:
ductal_carcinoma_in_situ
(Tumor type)
→
is_characterized_by
→
Object:
cribriform_pattern
(Organizational Structure)
Original: Ductal carcinoma in situ#is characterized by#small and uniform tumor cells growing in a cribriform pattern without comedo necrosis
#21199
high Confidence
Subject:
ductal_carcinoma_in_situ
(Tumor type)
→
is_characterized_by
→
Object:
small_uniform_tumor_cells
(Cell morphology)
Original: Ductal carcinoma in situ#is characterized by#small and uniform tumor cells growing in a cribriform pattern without comedo necrosis
#21132
high Confidence
Subject:
intranuclear_inclusions
(Nuclear inclusions)
→
is_associated_with
→
Object:
papillary_carcinoma
(Tumor type)
Original: Intranuclear inclusions/ papillary and/or sheet arrangements/ nuclear grooves/ powdery chromatin/ nuclear molding/ high cellularity/ and small nucleoli#were significantly associated with#papillary carcinoma
#21131
high Confidence
Subject:
SMARCA4_deficiency
(Loss of gene function)
→
is_associated_with
→
Object:
esophageal_carcinoma
(Tumor type)
Original: Esophageal carcinoma#is associated with#SMARCA4 deficiency or dysfunction
#20284
high Confidence
Subject:
Neuroendocrine tumors
(Tumor type)
→
showed
→
Object:
Ki-67_index_5%
(Proliferation markers)
Original: Neuroendocrine tumors#showed#cells arranged in cords or nests with Ki-67 index of 5% (G2 neuroendocrine tumor) and 80% (small-cell neuroendocrine carcinoma)
#19977
middle Confidence
Subject:
nuclear_molding
(Cell morphology)
→
shows
→
Object:
SCC_cases
(Tumor)
Original: Salt and pepper chromatin/ small cell size/ and nuclear molding#showed#90% sensitivity and 70% specificity for SCC cases
#19976
middle Confidence
Subject:
small_cell_size
(Cell morphology)
→
shows
→
Object:
SCC_cases
(Tumor)
Original: Salt and pepper chromatin/ small cell size/ and nuclear molding#showed#90% sensitivity and 70% specificity for SCC cases
#19975
middle Confidence
Subject:
salt_and_pepper_chromatin
(Cell morphology)
→
shows
→
Object:
SCC_cases
(Tumor)
Original: Salt and pepper chromatin/ small cell size/ and nuclear molding#showed#90% sensitivity and 70% specificity for SCC cases
#19651
middle Confidence
Subject:
Small_cell_carcinoma
(Tumor)
→
was_diagnosed_from
→
Object:
clinical_course
(Clinical course)
Original: Small cell carcinoma#was diagnosed from#histological features and clinical course
#19650
middle Confidence
Subject:
Small_cell_carcinoma
(Tumor)
→
was_diagnosed_from
→
Object:
histological_features
(Pathological characteristics)
Original: Small cell carcinoma#was diagnosed from#histological features and clinical course
#19515
middle Confidence
Subject:
small_medium_cell_clusters
(Cell clusters)
→
improves
→
Object:
diagnostic_specificity_for_adenocarcinoma
(Diagnostic specificity)
Original: Presence of nucleoli and small/medium cell clusters#improves#diagnostic sensitivity and specificity for adenocarcinoma
#19514
middle Confidence
Subject:
presence_of_nucleoli
(Nucleolus)
→
improves
→
Object:
diagnostic_sensitivity_for_adenocarcinoma
(Diagnostic sensitivity)
Original: Presence of nucleoli and small/medium cell clusters#improves#diagnostic sensitivity and specificity for adenocarcinoma
#19465
middle Confidence
Subject:
esophageal_tumor_biopsy
(Tumor samples)
→
showed
→
Object:
small_cell_carcinoma_with_hyperchromatic_nuclei
(Tumor type)
Original: esophageal tumor biopsy#showed#a small cell carcinoma with hyperchromatic nuclei
#18396
middle Confidence
Subject:
one_cell_type
(Tumor cell type)
→
showed_features_of
→
Object:
conventional_small_cell_neuroendocrine_carcinoma
(Tumor type)
Original: One cell type#showed features of#conventional small cell neuroendocrine carcinoma with granular chromatin/ immunohistochemical reactivity/ and electron-dense granules
#18099
middle Confidence
Subject:
123C3
(Monoclonal antibody markers)
→
is_useful_marker_for
→
Object:
gastric_small_cell_carcinoma
(Tumor)
Original: Leu-7 and 123C3 monoclonal antibodies#are useful markers for#gastric small cell carcinoma
#18098
middle Confidence
Subject:
Leu-7
(Monoclonal antibody markers)
→
is_useful_marker_for
→
Object:
gastric_small_cell_carcinoma
(Tumor)
Original: Leu-7 and 123C3 monoclonal antibodies#are useful markers for#gastric small cell carcinoma
#17901
middle Confidence
Subject:
liver_cells
(Hepatocytes)
→
in_hepatocellular_carcinoma
→
Object:
small_cytoplasmic_vacuoles
(Cell phenotype)
Original: Liver cells in hepatocellular carcinoma#are characterized by#a high nucleus/cytoplasm ratio/ large cell diameters/ increased nucleoli/ and small cytoplasmic vacuoles
#17900
middle Confidence
Subject:
liver_cells
(Hepatocytes)
→
in_hepatocellular_carcinoma
→
Object:
increased_nucleoli
(Cell phenotype)
Original: Liver cells in hepatocellular carcinoma#are characterized by#a high nucleus/cytoplasm ratio/ large cell diameters/ increased nucleoli/ and small cytoplasmic vacuoles
#17899
middle Confidence
Subject:
liver_cells
(Hepatocytes)
→
in_hepatocellular_carcinoma
→
Object:
large_cell_diameters
(Cell phenotype)
Original: Liver cells in hepatocellular carcinoma#are characterized by#a high nucleus/cytoplasm ratio/ large cell diameters/ increased nucleoli/ and small cytoplasmic vacuoles
#17898
middle Confidence
Subject:
liver_cells
(Hepatocytes)
→
in_hepatocellular_carcinoma
→
Object:
high_nucleus_cytoplasm_ratio
(Cell phenotype)
Original: Liver cells in hepatocellular carcinoma#are characterized by#a high nucleus/cytoplasm ratio/ large cell diameters/ increased nucleoli/ and small cytoplasmic vacuoles
#17862
middle Confidence
Subject:
small_cell_mesothelioma
(Tumor diseases)
→
is_mistaken_for
→
Object:
small_cell_lung_carcinoma
(Tumor diseases)
Original: small cell mesothelioma (SCM)#is mistaken for#small cell lung carcinoma (SCLC)
#17511
middle Confidence
Subject:
SMCC
(Tumor cell type)
→
shows
→
Object:
inconspicuous_nucleoli
(Cell morphology)
Original: SMCC#showed#nuclear molding/ salt and pepper chromatin/ and inconspicuous nucleoli
#17510
middle Confidence
Subject:
SMCC
(Tumor cell type)
→
shows
→
Object:
salt_and_pepper_chromatin
(Cell morphology)
Original: SMCC#showed#nuclear molding/ salt and pepper chromatin/ and inconspicuous nucleoli
#17509
middle Confidence
Subject:
SMCC
(Tumor cell type)
→
shows
→
Object:
nuclear_molding
(Cell morphology)
Original: SMCC#showed#nuclear molding/ salt and pepper chromatin/ and inconspicuous nucleoli
#17348
middle Confidence
Subject:
Small_cell_component
(Tumor cells)
→
stains_for
→
Object:
keratin
(protein)
Original: Small cell component#stains for#keratin
#16381
middle Confidence
Subject:
nucleolar_organizer_region
(Nucleolar organizing region)
→
is_present_in
→
Object:
small_cell_carcinoma
(Small cell carcinoma)
Original: Argyrophil technique#demonstrates#nucleolar organizer regions in small cell carcinoma
#16380
middle Confidence
Subject:
argyrophil_technique
(Dyeing technology)
→
demonstrates
→
Object:
nucleolar_organizer_region
(Nucleolar organizing region)
Original: Argyrophil technique#demonstrates#nucleolar organizer regions in small cell carcinoma
#16360
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
are_sensitive_and_specific_for
→
Object:
distinguishing_NSCC
(Tumor)
Original: Cytologic features#are sensitive and specific for#distinguishing SCC from NSCC
#16359
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
are_sensitive_and_specific_for
→
Object:
distinguishing_SCC
(Tumor)
Original: Cytologic features#are sensitive and specific for#distinguishing SCC from NSCC
#16358
middle Confidence
Subject:
cytopathologic_differential_diagnosis
(Diagnostic Methods)
→
conducted_for
→
Object:
poorly_differentiated_non_small_cell_carcinoma
(Tumor)
Original: Cytopathologic differential diagnosis#was conducted for#small cell carcinoma and poorly differentiated non-small cell carcinoma
#16357
middle Confidence
Subject:
cytopathologic_differential_diagnosis
(Diagnostic Methods)
→
conducted_for
→
Object:
small_cell_carcinoma
(Tumor)
Original: Cytopathologic differential diagnosis#was conducted for#small cell carcinoma and poorly differentiated non-small cell carcinoma
#16241
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
melanoma
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16240
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
non-Hodgkin_lymphoma_leukemia
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16239
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
small_round_cell_tumors
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16238
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
undifferentiated_tumors
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16237
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
SMARCA4-deficient_thoracic_sarcoma
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16236
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
thymic_carcinoma
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16235
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
small_cell_carcinoma
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16234
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
basaloid_carcinoma_of_the_lung
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#15031
middle Confidence
Subject:
Case
(Case)
→
was_misdiagnosed_as
→
Object:
Small-cell_lung_carcinoma
(Neoplastic diseases)
Original: Remaining two cases#were misdiagnosed as#small-cell lung carcinoma
#14900
middle Confidence
Subject:
carcinoma_cells
(Tumor cells)
→
show
→
Object:
scant_compact_chromatin_arranged_in_small_masses
(Cell morphology)
Original: Carcinoma cells#showed#scant compact chromatin arranged in small masses
#14775
middle Confidence
Subject:
presence_of_single_cells
(Single Cell)
→
improves
→
Object:
diagnostic_accuracy_for_small_cell_carcinoma
(Diagnostic Accuracy)
Original: Moderate necrosis (<50%) and presence of single cells#improves#diagnostic accuracy for small cell carcinoma
#14774
middle Confidence
Subject:
moderate_necrosis_<50%
(Moderate necrosis <50%)
→
improves
→
Object:
diagnostic_accuracy_for_small_cell_carcinoma
(Diagnostic Accuracy)
Original: Moderate necrosis (<50%) and presence of single cells#improves#diagnostic accuracy for small cell carcinoma
#14224
middle Confidence
Subject:
neuroendocrine_carcinoma_cells
(Tumor cell type)
→
are_characterized_by
→
Object:
absence_of_nucleoli
(Nucleolar morphology)
Original: Neuroendocrine carcinoma cells#were characterized by#dense packing/ small size/ scant cytoplasm/ finely granular nuclear chromatin/ and absence of nucleoli
#14223
middle Confidence
Subject:
neuroendocrine_carcinoma_cells
(Tumor cell type)
→
are_characterized_by
→
Object:
finely_granular_nuclear_chromatin
(Chromatin morphology characteristics)
Original: Neuroendocrine carcinoma cells#were characterized by#dense packing/ small size/ scant cytoplasm/ finely granular nuclear chromatin/ and absence of nucleoli
#14222
middle Confidence
Subject:
neuroendocrine_carcinoma_cells
(Tumor cell type)
→
are_characterized_by
→
Object:
scant_cytoplasm
(Cytoplasmic morphology)
Original: Neuroendocrine carcinoma cells#were characterized by#dense packing/ small size/ scant cytoplasm/ finely granular nuclear chromatin/ and absence of nucleoli
#14221
middle Confidence
Subject:
neuroendocrine_carcinoma_cells
(Tumor cell type)
→
are_characterized_by
→
Object:
small_size
(Cell volume characteristics)
Original: Neuroendocrine carcinoma cells#were characterized by#dense packing/ small size/ scant cytoplasm/ finely granular nuclear chromatin/ and absence of nucleoli
#14220
middle Confidence
Subject:
neuroendocrine_carcinoma_cells
(Tumor cell type)
→
are_characterized_by
→
Object:
dense_packing
(Cell arrangement characteristics)
Original: Neuroendocrine carcinoma cells#were characterized by#dense packing/ small size/ scant cytoplasm/ finely granular nuclear chromatin/ and absence of nucleoli
#14203
middle Confidence
Subject:
cells
(cell)
→
display
→
Object:
irregular_mitochondria
(Organelles)
Original: Cells#display#small and irregular mitochondria
#14202
middle Confidence
Subject:
cells
(cell)
→
display
→
Object:
small_mitochondria
(Organelles)
Original: Cells#display#small and irregular mitochondria
#14099
middle Confidence
Subject:
small_cell_carcinoma
(Tumor type)
→
metastasized_to
→
Object:
right_inguinal_lymph_node
(Anatomy)
Original: A 51-year-old male#presented with#metastasis of a small cell carcinoma of unknown origin in a right inguinal lymph node
#13855
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_composed_of
→
Object:
central_nucleolus
(Cell morphology)
Original: NUT carcinoma#is composed of#poorly differentiated sheets of small cells with scant cytoplasm/ round nucleus/ and central nucleolus
#13854
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_composed_of
→
Object:
round_nucleus
(Cell morphology)
Original: NUT carcinoma#is composed of#poorly differentiated sheets of small cells with scant cytoplasm/ round nucleus/ and central nucleolus
#13853
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_composed_of
→
Object:
scant_cytoplasm
(Cell morphology)
Original: NUT carcinoma#is composed of#poorly differentiated sheets of small cells with scant cytoplasm/ round nucleus/ and central nucleolus
#13852
middle Confidence
Subject:
NUT_carcinoma
(Tumor type)
→
is_composed_of
→
Object:
poorly_differentiated_small_cells
(Cell morphology)
Original: NUT carcinoma#is composed of#poorly differentiated sheets of small cells with scant cytoplasm/ round nucleus/ and central nucleolus
#13457
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are
→
Object:
smaller_than_adenocarcinoma_cells
(Cell morphology)
Original: epithelial cells#are#round to oval/ more uniform and smaller than adenocarcinoma cells
#13456
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are
→
Object:
more_uniform_and_smaller_than_adenocarcinoma_cells
(Cell morphology)
Original: epithelial cells#are#round to oval/ more uniform and smaller than adenocarcinoma cells
#13455
middle Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are
→
Object:
round_to_oval
(Cell morphology)
Original: epithelial cells#are#round to oval/ more uniform and smaller than adenocarcinoma cells
#13365
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic techniques)
→
diagnoses
→
Object:
small_cell_neuroendocrine_carcinoma_of_the_breast
(Disease name)
Original: fine-needle aspiration cytology#diagnoses#small cell neuroendocrine carcinoma of the breast
#13361
middle Confidence
Subject:
histological_findings
(Pathological findings)
→
led_to
→
Object:
diagnosis_of_combined_small_cell_carcinoma_with_renal_graft_involvement
(Disease diagnosis)
Original: histological findings#led to#conclusion about combined small cell carcinoma with renal graft involvement
#13052
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
identified_as
→
Object:
poorly_differentiated_small_cells
(Cell morphology)
Original: 10 cases#were identified as#poorly differentiated small cells
#13010
middle Confidence
Subject:
neoplasm
(Tumor)
→
resembles
→
Object:
small_cell_carcinoma_of_hypercalcemic_type
(Tumor subtype)
Original: neoplasm#is associated with#hypercalcemia and resembles small cell carcinoma of hypercalcemic type
#13009
middle Confidence
Subject:
neoplasm
(Tumor)
→
is_associated_with
→
Object:
hypercalcemia
(Metabolic abnormalities)
Original: neoplasm#is associated with#hypercalcemia and resembles small cell carcinoma of hypercalcemic type
#12990
middle Confidence
Subject:
Small_cell_component
(Histiocyte subtype)
→
stains_for
→
Object:
Leu_7
(Cell surface molecules)
Original: Small cell component#stains for#Leu-7
#12989
middle Confidence
Subject:
Small_cell_component
(Histiocyte subtype)
→
stains_for
→
Object:
Chromogranin
(Secretory granule protein)
Original: Small cell component#stains for#chromogranin
#12988
middle Confidence
Subject:
Small_cell_component
(Histiocyte subtype)
→
stains_for
→
Object:
neuron_specific_enolase
(Enzyme Protein)
Original: Small cell component#stains for#neuron-specific enolase
#12987
middle Confidence
Subject:
Small_cell_component
(Histiocyte subtype)
→
stains_for
→
Object:
epithelial_membrane_antigen
(Membrane Protein)
Original: Small cell component#stains for#epithelial membrane antigen
#12653
middle Confidence
Subject:
TOP1
(DNA topoisomerase)
→
expression_is_assessed_in
→
Object:
NSCLC_tumor_samples
(Tumor tissue)
Original: Expression of topoisomerase genes#is assessed in#non-small cell lung carcinoma tumor samples
#11815
middle Confidence
Subject:
cellular_proliferation_ratio_in_papillomas
(Cellular Processes)
→
is_smaller_than
→
Object:
carcinomas
(Disease phenotype)
Original: Cellular proliferation ratio in papillomas#is greater than#hyperplasias and smaller than carcinomas
#11814
middle Confidence
Subject:
cellular_proliferation_ratio_in_papillomas
(Cellular Processes)
→
is_greater_than
→
Object:
hyperplasia
(Disease phenotype)
Original: Cellular proliferation ratio in papillomas#is greater than#hyperplasias and smaller than carcinomas
#11419
middle Confidence
Subject:
Parameters
(Diagnostic parameters)
→
distinguish
→
Object:
small_cell_carcinoma_of_pulmonary_origin
(Disease Type)
Original: Parameters#distinguish#small cell malignancies from small cell carcinoma of pulmonary origin
#11418
middle Confidence
Subject:
Parameters
(Diagnostic parameters)
→
distinguish
→
Object:
small_cell_malignancies
(Disease Type)
Original: Parameters#distinguish#small cell malignancies from small cell carcinoma of pulmonary origin
#11368
middle Confidence
Subject:
one_cell_type
(Tumor cell type)
→
showed_features_of
→
Object:
electron-dense_granules
(Cell structure characteristics)
Original: One cell type#showed features of#conventional small cell neuroendocrine carcinoma with granular chromatin/ immunohistochemical reactivity/ and electron-dense granules
#11367
middle Confidence
Subject:
one_cell_type
(Tumor cell type)
→
showed_features_of
→
Object:
granular_chromatin
(Cell structure characteristics)
Original: One cell type#showed features of#conventional small cell neuroendocrine carcinoma with granular chromatin/ immunohistochemical reactivity/ and electron-dense granules
#11260
middle Confidence
Subject:
mixed_tumor
(Tumor type)
→
is_composed_of
→
Object:
transitional_carcinoma
(Tumor type)
Original: mixed tumor#is composed of#undifferentiated small cells and transitional carcinoma
#11259
middle Confidence
Subject:
mixed_tumor
(Tumor type)
→
is_composed_of
→
Object:
undifferentiated_small_cells
(Tumor cells)
Original: mixed tumor#is composed of#undifferentiated small cells and transitional carcinoma
#10528
middle Confidence
Subject:
pleural_neoplasm
(Tumor tissue)
→
is_composed_of
→
Object:
small_cell_carcinoma
(Tumor diseases)
Original: pleural neoplasm#is composed of#malignant epithelial mesothelioma/ small- to medium-sized cells/ and small cell carcinoma
#10527
middle Confidence
Subject:
pleural_neoplasm
(Tumor tissue)
→
is_composed_of
→
Object:
small_to_medium_sized_cells
(Cell Type)
Original: pleural neoplasm#is composed of#malignant epithelial mesothelioma/ small- to medium-sized cells/ and small cell carcinoma
#10526
middle Confidence
Subject:
pleural_neoplasm
(Tumor tissue)
→
is_composed_of
→
Object:
malignant_epithelial_mesothelioma
(Tumor diseases)
Original: pleural neoplasm#is composed of#malignant epithelial mesothelioma/ small- to medium-sized cells/ and small cell carcinoma
#10525
middle Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic techniques)
→
is_compared_for
→
Object:
small_cell_carcinoma
(Tumor diseases)
Original: fine-needle aspiration cytology#is compared for#basaloid squamous cell carcinoma and small cell carcinoma
#10524
middle Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic techniques)
→
is_compared_for
→
Object:
basaloid_squamous_cell_carcinoma
(Tumor diseases)
Original: fine-needle aspiration cytology#is compared for#basaloid squamous cell carcinoma and small cell carcinoma
#10352
middle Confidence
Subject:
Extrapulmonary_small_cell_carcinoma
(Tumor type)
→
shares_features_with
→
Object:
pulmonary_small_cell_carcinoma
(Tumor type)
Original: Extrapulmonary small cell carcinoma#shares#features with pulmonary small cell carcinoma
#9702
middle Confidence
Subject:
Neuroendocrine tumors
(Tumor type)
→
showed
→
Object:
cells_arranged_in_cords_or_nests
(Histological structure)
Original: Neuroendocrine tumors#showed#cells arranged in cords or nests with Ki-67 index of 5% (G2 neuroendocrine tumor) and 80% (small-cell neuroendocrine carcinoma)
#9293
middle Confidence
Subject:
adenocarcinoma_cells
(Tumor cells)
→
have
→
Object:
abundant_eosinophilic_cytoplasm
(Cytoplasmic characteristics)
Original: Poorly differentiated adenocarcinoma cells#have#a pleomorphic nucleus/ small eosinophilic nucleolus/ and abundant eosinophilic cytoplasm
#9292
middle Confidence
Subject:
adenocarcinoma_cells
(Tumor cells)
→
have
→
Object:
small_eosinophilic_nucleolus
(Cell nucleolus characteristics)
Original: Poorly differentiated adenocarcinoma cells#have#a pleomorphic nucleus/ small eosinophilic nucleolus/ and abundant eosinophilic cytoplasm
#9291
middle Confidence
Subject:
adenocarcinoma_cells
(Tumor cells)
→
have
→
Object:
pleomorphic_nucleus
(Nuclear morphology)
Original: Poorly differentiated adenocarcinoma cells#have#a pleomorphic nucleus/ small eosinophilic nucleolus/ and abundant eosinophilic cytoplasm
#9068
middle Confidence
Subject:
KIT
(Receptor tyrosine kinases)
→
shows_strong_immunoreaction_in
→
Object:
Extrapulmonary_small_cell_carcinoma
(Tumor diseases)
Original: Strong immunoreactions#were seen for#CD56 and c-kit
#9067
middle Confidence
Subject:
CD56
(Cell surface molecules)
→
shows_strong_immunoreaction_in
→
Object:
Extrapulmonary_small_cell_carcinoma
(Tumor diseases)
Original: Strong immunoreactions#were seen for#CD56 and c-kit
#9044
middle Confidence
Subject:
small cell carcinoma
(Tumor type)
→
is_distinguished_from
→
Object:
poorly differentiated prostate carcinoma
(Tumor type)
Original: small-cell carcinoma#is distinguished from#poorly differentiated prostate carcinoma by cell size/ finely stippled chromatin/ inconspicuous nucleoli
#7424
middle Confidence
Subject:
small_sized_tumor_cell
(Tumor cells)
→
exhibits
→
Object:
absence_of_nucleolus
(Nuclear structure)
Original: Small-sized tumor cells#exhibit#absence of nucleoli
#7233
middle Confidence
Subject:
Primary_small_cell_carcinomas
(Tumor)
→
are_rare_in
→
Object:
domestic_animals
(animal)
Original: Primary small cell carcinomas#are rare in#domestic animals
#7084
middle Confidence
Subject:
Cytologic_features
(Cell morphology)
→
includes
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Cytologic features#included#small to moderate-sized loose groups with numerous single cells/ prominent acinar formation/ little anisonucleosis/ and prominent nucleoli
#7083
middle Confidence
Subject:
Cytologic_features
(Cell morphology)
→
includes
→
Object:
little_anisonucleosis
(Cell morphology)
Original: Cytologic features#included#small to moderate-sized loose groups with numerous single cells/ prominent acinar formation/ little anisonucleosis/ and prominent nucleoli
#7082
middle Confidence
Subject:
Cytologic_features
(Cell morphology)
→
includes
→
Object:
prominent_acinar_formation
(Cell morphology)
Original: Cytologic features#included#small to moderate-sized loose groups with numerous single cells/ prominent acinar formation/ little anisonucleosis/ and prominent nucleoli
#7081
middle Confidence
Subject:
Cytologic_features
(Cell morphology)
→
includes
→
Object:
numerous_single_cells
(Cell morphology)
Original: Cytologic features#included#small to moderate-sized loose groups with numerous single cells/ prominent acinar formation/ little anisonucleosis/ and prominent nucleoli
#7080
middle Confidence
Subject:
Cytologic_features
(Cell morphology)
→
includes
→
Object:
small_to_moderate_sized_loose_groups
(Cell morphology)
Original: Cytologic features#included#small to moderate-sized loose groups with numerous single cells/ prominent acinar formation/ little anisonucleosis/ and prominent nucleoli
#6164
middle Confidence
Subject:
small_cell_carcinoma
(Tumor pathology type)
→
misdiagnosed_as
→
Object:
nonprostatic_origin
(Disease phenotype)
Original: carcinoid-like lesions and small cell carcinomas#were misdiagnosed as#nonprostatic origin based on immunoreactivity
#6163
middle Confidence
Subject:
carcinoid-like_lesion
(Tumor pathology type)
→
misdiagnosed_as
→
Object:
nonprostatic_origin
(Disease phenotype)
Original: carcinoid-like lesions and small cell carcinomas#were misdiagnosed as#nonprostatic origin based on immunoreactivity
#6006
middle Confidence
Subject:
AgNOR_size
(Nucleolar organizer region-associated)
→
decreases_with
→
Object:
carcinoma_grade
(Disease classification)
Original: AgNOR size#became smaller with#increasing grade of carcinoma
#5828
middle Confidence
Subject:
bronchial_lavage_specimens
(Sample Type)
→
examined_from
→
Object:
NSCC_cases
(Tumor)
Original: Bronchial lavage specimens#were examined from#35 SCC cases and 63 NSCC cases
#5827
middle Confidence
Subject:
bronchial_lavage_specimens
(Sample Type)
→
examined_from
→
Object:
SCC_cases
(Tumor)
Original: Bronchial lavage specimens#were examined from#35 SCC cases and 63 NSCC cases
#5820
middle Confidence
Subject:
Pathological_findings
(Pathological examination)
→
showed
→
Object:
nests_of_small_round_cells_with_fine_granular_chromatin
(Cell morphology)
Original: Pathological findings#showed#nests of small round cells with fine granular chromatin
#5367
middle Confidence
Subject:
smears
(Cytology specimens)
→
reveal
→
Object:
nuclear_moulding
(Nuclear characteristics)
Original: Smears#revealed#small round cells with scant cytoplasm and nuclear moulding
#5366
middle Confidence
Subject:
smears
(Cytology specimens)
→
reveal
→
Object:
small_round_cells_with_scant_cytoplasm
(Cell morphology)
Original: Smears#revealed#small round cells with scant cytoplasm and nuclear moulding
#4924
middle Confidence
Subject:
large_cells
(Tumor cells)
→
showed
→
Object:
abundant_cytoplasm_and_irregular_nucleus
(Cell morphology)
Original: large cells#showed#abundant cytoplasm/ irregular nucleus with nucleolus/ initially diagnosed as non-small cell carcinoma of the lung
#4894
middle Confidence
Subject:
Synaptophysin
(Synaptic vesicle protein)
→
shows_sparse_immunoreaction_in
→
Object:
Extrapulmonary_small_cell_carcinoma
(Tumor diseases)
Original: Sparse immunoreaction#was seen for#synaptophysin
#4749
middle Confidence
Subject:
cytokeratin_AE1/AE3
(Cytokeratin)
→
shows
→
Object:
partial_dot-like_distribution
(Protein localization characteristics)
Original: Cytokeratin AE1/AE3 staining#was#predominantly membranous with partial dot-like distribution
#4748
middle Confidence
Subject:
cytokeratin_AE1/AE3
(Cytokeratin)
→
shows
→
Object:
predominantly_membranous_staining
(Protein localization characteristics)
Original: Cytokeratin AE1/AE3 staining#was#predominantly membranous with partial dot-like distribution
#4717
middle Confidence
Subject:
Standard_treatment
(Treatment options)
→
has_not_been_established
→
Object:
Primary_small_cell_carcinoma_of_the_vagina
(disease)
Original: Standard treatment#has not been#established
#4716
middle Confidence
Subject:
Primary_small_cell_carcinoma_of_the_vagina
(disease)
→
is
→
Object:
extremely_rare
(Disease characteristics)
Original: Primary small cell carcinoma of the vagina#is#extremely rare
#4571
middle Confidence
Subject:
appearance_of_nucleoli
(Cell nucleolus morphology)
→
helps_in
→
Object:
diagnosis_of_small_cell_carcinoma
(Tumor type diagnosis)
Original: Appearance of nucleoli#helps in#diagnosis of lymphoma or small cell carcinoma by LM
#4570
middle Confidence
Subject:
appearance_of_nucleoli
(Cell nucleolus morphology)
→
helps_in
→
Object:
diagnosis_of_lymphoma
(Tumor type diagnosis)
Original: Appearance of nucleoli#helps in#diagnosis of lymphoma or small cell carcinoma by LM
#4569
middle Confidence
Subject:
nuclear_structure_of_tumor_cells
(Nuclear structure)
→
differentiations
→
Object:
small_cell_carcinoma
(Tumor type)
Original: Nuclear structure of tumor cells#differentiates#lymphoma from small cell carcinoma
#4568
middle Confidence
Subject:
nuclear_structure_of_tumor_cells
(Nuclear structure)
→
differentiations
→
Object:
lymphoma
(Tumor type)
Original: Nuclear structure of tumor cells#differentiates#lymphoma from small cell carcinoma
#3422
low Confidence
Subject:
small cell anaplastic carcinoma of the prostate
(Tumor type)
→
was_diagnosed_in
→
Object:
patient
(patient)
Original: Small cell anaplastic carcinoma of the prostate#was diagnosed in#a patient
#3269
low Confidence
Subject:
small_clusters
(Cell structure)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: adenocarcinoma cells#were observed as#small clusters with eccentric nuclei and prominent nucleoli
#3268
low Confidence
Subject:
small_clusters
(Cell structure)
→
are_characterized_by
→
Object:
eccentric_nuclei
(Nuclear characteristics)
Original: adenocarcinoma cells#were observed as#small clusters with eccentric nuclei and prominent nucleoli
#3267
low Confidence
Subject:
adenocarcinoma_cells
(cancer cell)
→
are_observed_as
→
Object:
small_clusters
(Cell structure)
Original: adenocarcinoma cells#were observed as#small clusters with eccentric nuclei and prominent nucleoli
#3105
low Confidence
Subject:
light_and_ultrastructural_features
(Morphological characteristics)
→
characterize
→
Object:
lymphoma
(Tumor type)
Original: EM specimens#were reviewed for#light and ultrastructural features of small cell carcinoma and lymphoma
#3104
low Confidence
Subject:
light_and_ultrastructural_features
(Morphological characteristics)
→
characterize
→
Object:
small_cell_carcinoma
(Tumor type)
Original: EM specimens#were reviewed for#light and ultrastructural features of small cell carcinoma and lymphoma
#2749
low Confidence
Subject:
NOR_in_small_cell_carcinoma_cells
(Nuclear structure)
→
showed
→
Object:
dots_slightly_variable_in_size_and_shape
(Cell morphology)
Original: NOR in small cell carcinoma cells#showed#dots slightly variable in size and shape
#2211
low Confidence
Subject:
EM_specimens
(Tissue samples)
→
were_reviewed_for
→
Object:
light_and_ultrastructural_features
(Morphological characteristics)
Original: EM specimens#were reviewed for#light and ultrastructural features of small cell carcinoma and lymphoma
#2016
low Confidence
Subject:
case
(Case)
→
was_misdiagnosed_as
→
Object:
anaplastic_carcinoma
(Tumor)
Original: Three cases#were misdiagnosed as#anaplastic carcinoma of the small-cell type
#1610
low Confidence
Subject:
lesion
(Tumor lesions)
→
represented
→
Object:
desmoplastic_small_round_cell_tumor
(Tumor diseases)
Original: lesions#represented#leiomyosarcoma/ gastric carcinoma/ epithelioid sarcoma/ Merkel cell carcinoma/ and desmoplastic small round cell tumor
#1609
low Confidence
Subject:
lesion
(Tumor lesions)
→
represented
→
Object:
Merkel_cell_carcinoma
(Tumor diseases)
Original: lesions#represented#leiomyosarcoma/ gastric carcinoma/ epithelioid sarcoma/ Merkel cell carcinoma/ and desmoplastic small round cell tumor
#1608
low Confidence
Subject:
lesion
(Tumor lesions)
→
represented
→
Object:
epithelioid_sarcoma
(Tumor diseases)
Original: lesions#represented#leiomyosarcoma/ gastric carcinoma/ epithelioid sarcoma/ Merkel cell carcinoma/ and desmoplastic small round cell tumor
#1607
low Confidence
Subject:
lesion
(Tumor lesions)
→
represented
→
Object:
gastric_carcinoma
(Tumor diseases)
Original: lesions#represented#leiomyosarcoma/ gastric carcinoma/ epithelioid sarcoma/ Merkel cell carcinoma/ and desmoplastic small round cell tumor
#1606
low Confidence
Subject:
lesion
(Tumor lesions)
→
represented
→
Object:
leiomyosarcoma
(Tumor diseases)
Original: lesions#represented#leiomyosarcoma/ gastric carcinoma/ epithelioid sarcoma/ Merkel cell carcinoma/ and desmoplastic small round cell tumor
#1220
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
granulocytic_sarcoma
(Disease phenotype)
Original: Differential diagnoses#included#inflammatory lesions/ small cell carcinoma/ endometrial stromal sarcoma/ granulocytic sarcoma
#1219
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
endometrial_stromal_sarcoma
(Disease phenotype)
Original: Differential diagnoses#included#inflammatory lesions/ small cell carcinoma/ endometrial stromal sarcoma/ granulocytic sarcoma
#1218
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
small_cell_carcinoma
(Disease phenotype)
Original: Differential diagnoses#included#inflammatory lesions/ small cell carcinoma/ endometrial stromal sarcoma/ granulocytic sarcoma
#1217
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
inflammatory_lesions
(Disease phenotype)
Original: Differential diagnoses#included#inflammatory lesions/ small cell carcinoma/ endometrial stromal sarcoma/ granulocytic sarcoma
#298
low Confidence
Subject:
tumors
(Tumor tissue)
→
did_not_show
→
Object:
haematoxyphilic_blood_vessels
(Organizational form)
Original: tumors#did not show#streams/ ribbons/ rosettes/ or haematoxyphilic blood vessels typical of small cell carcinoma
#297
low Confidence
Subject:
tumors
(Tumor tissue)
→
did_not_show
→
Object:
rosettes
(Organizational form)
Original: tumors#did not show#streams/ ribbons/ rosettes/ or haematoxyphilic blood vessels typical of small cell carcinoma
#296
low Confidence
Subject:
tumors
(Tumor tissue)
→
did_not_show
→
Object:
ribbons
(Organizational form)
Original: tumors#did not show#streams/ ribbons/ rosettes/ or haematoxyphilic blood vessels typical of small cell carcinoma
#295
low Confidence
Subject:
tumors
(Tumor tissue)
→
did_not_show
→
Object:
streams
(Organizational form)
Original: tumors#did not show#streams/ ribbons/ rosettes/ or haematoxyphilic blood vessels typical of small cell carcinoma