List of serched triples
A total of 22252 records found
#22132
high Confidence
Subject:
FBL_gene
(Protein coding genes)
→
is_crucial_for
→
Object:
eukaryotic_cells
(Eukaryotic cells)
Original: FBL gene#is crucial for#eukaryotic cells
#22131
high Confidence
Subject:
rDNA
(DNA sequence)
→
encodes
→
Object:
ribosomal_RNA
(rRNA)
Original: NORs (rDNA)#encode#ribosomal RNA
#22130
high Confidence
Subject:
p53
(Transcription Factors)
→
interacts_with
→
Object:
MDM2
(protein)
Original: Interaction with p53 and transcription inhibition#are necessary for#MDM2 function
#22129
high Confidence
Subject:
MDM2
(protein)
→
binds_to
→
Object:
p53
(Transcription Factors)
Original: MDM2 oncoprotein#binds to#p53
#22128
high Confidence
Subject:
NPM1_mutation
(Gene mutation)
→
is_regarded_as
→
Object:
distinct_genetic_entity_in_WHO_classification
(Molecular typing)
Original: NPM1 mutation#is regarded as#a distinct genetic entity in the WHO classification of hematopoietic malignancies
#22127
high Confidence
Subject:
5_fluorouracil
(Small molecule drugs)
→
activates
→
Object:
p53
(Transcription Factors)
Original: 5-fluorouracil#activates#p53 by inducing ribosomal stress
#22126
high Confidence
Subject:
NRG1
(Protein coding genes)
→
is_oncogenic_driver_in
→
Object:
solid_tumors
(Tumor)
Original: NRG1 gene fusions#are#emerging oncogenic drivers in solid tumors
#22125
high Confidence
Subject:
CTLA-4_inhibitor
(Immune checkpoint inhibitors)
→
produces
→
Object:
significant_clinical_response
(Clinical response)
Original: Immunotherapy with PD-1/PD-L1/CTLA-4 inhibitors#produced#significant clinical responses
#22124
high Confidence
Subject:
PD-L1_inhibitor
(Immune checkpoint inhibitors)
→
produces
→
Object:
significant_clinical_response
(Clinical response)
Original: Immunotherapy with PD-1/PD-L1/CTLA-4 inhibitors#produced#significant clinical responses
#22123
high Confidence
Subject:
PD-1_inhibitor
(Immune checkpoint inhibitors)
→
produces
→
Object:
significant_clinical_response
(Clinical response)
Original: Immunotherapy with PD-1/PD-L1/CTLA-4 inhibitors#produced#significant clinical responses
#22122
high Confidence
Subject:
PSF-TFE3_fusion_gene
(Gene fusion products)
→
confirmed_by
→
Object:
reverse_transcription_PCR
(Detection Methods)
Original: PSF-TFE3 fusion genes#were confirmed by#reverse transcription polymerase chain reaction
#22121
high Confidence
Subject:
FH
(Protein coding genes)
→
mutated_in
→
Object:
HLRCC_syndrome
(Rare genetic diseases)
Original: Mutations in FH gene#underlie#HLRCC syndrome
#22120
high Confidence
Subject:
UBF1
(Transcription Factors)
→
interacts_with
→
Object:
rDNA_promoter
(DNA sequence)
Original: UBF1#interacts with#the promoter of rRNA genes (rDNA)
#22119
high Confidence
Subject:
UBF
(Transcription Factors)
→
initiates
→
Object:
rRNA_transcription
(Molecular Process)
Original: Upstream binding factor (UBF)#recognizes#ribosomal RNA gene promoter and initiates transcription
#22118
high Confidence
Subject:
UBF
(Transcription Factors)
→
recognizes
→
Object:
rRNA_gene_promoter
(DNA sequence)
Original: Upstream binding factor (UBF)#recognizes#ribosomal RNA gene promoter and initiates transcription
#22117
high Confidence
Subject:
RPS14
(Ribosomal proteins)
→
inhibits
→
Object:
CDK6
(Kinase)
Original: RPS14#acts as#a CDK4/6 inhibitor linking ribosome biogenesis defects to cell cycle progression
#22116
high Confidence
Subject:
RPS14
(Ribosomal proteins)
→
inhibits
→
Object:
CDK4
(Kinase)
Original: RPS14#acts as#a CDK4/6 inhibitor linking ribosome biogenesis defects to cell cycle progression
#22115
high Confidence
Subject:
Nutlin-3
(Small molecule drugs)
→
activates
→
Object:
p53
(Tumor suppressor proteins)
Original: Nutlin-3#impairs#erythropoiesis by activating p53
#22114
high Confidence
Subject:
TP53
(Tumor suppressor genes)
→
is_involved_in
→
Object:
tumor_suppression
(Tumor suppressor function)
Original: GLTSCR2#is involved in#tumor suppression with p53/ NPM/ and MYC
#22113
high Confidence
Subject:
TP53
(Tumor suppressor genes)
→
acts_as
→
Object:
tumor_suppressor
(Tumor suppressor function)
Original: p14ARF/ARF#acts as#a tumor suppressor through a p53/MDM2-dependent pathway